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Journal articles on the topic 'Coronary diseases'

Author: Grafiati

Published: 4 June 2021

Last updated: 30 January 2023

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1

Habib Afzal, Qari Hafiz Muhammad, Kamran Ruaf, Areej Umber Khan, Asma Ashfaq, Muhammad Bilal Basit, and Khalid Mahmood Anjum. "CORONARY ARTERY DISEASES;." Professional Medical Journal 24, no. 10 (October 6, 2017): 1471–75. http://dx.doi.org/10.29309/tpmj/2017.24.10.714.

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Introduction: Ischemic heart disease (IHD) is one of the leading causes ofdeath. Short sleep duration may increase the risk of coronary artery disease (CAD). The studywas designed to evaluate the association between CAD and sleep duration. Objectives: Todetermine the frequency of patients who have short sleep duration may suffer from CAD. Studydesign: Case series. Setting: Punjab Institute of Cardiology (PIC), Lahore. Period: It was carriedout in six months. Methods: 400 patients admitted who presented with IHD. Sleep durationwas categorized into three categories like <6 hours, 6-8 hours and >8 hours. Angiographywas performed for patients who have CAD. Results: Sleep duration was <6 hours, 6–8 hours,and >8 hours in 172 (43%), 124 (31%) and 104 (26%) patients respectively. Significant CADwas presented among 84 (21%) patients of sleep duration <6 hours, 16 (4%) patients of sleepduration 6–8 hours and 32 (8%) patients of >8 hours sleep duration. Conclusions: Significantnumber of patients has short sleep time and suffering from CAD.

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2

Chen, James T. T. "Coronary Artery Diseases." Radiology 162, no. 2 (February 1987): 376. http://dx.doi.org/10.1148/radiology.162.2.376.

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3

Paramjyothi, G. "Respiratory Diseases and Coronary Artery Diseases." Indian Journal of Cardiovascular Disease in Women WINCARS 02, no. 01 (March 2017): 056–67. http://dx.doi.org/10.1055/s-0038-1656461.

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4

Horák, David. "Nonatherosclerotic coronary artery diseases." Intervenční a akutní kardiologie 18, no. 1 (March 8, 2019): 23–27. http://dx.doi.org/10.36290/kar.2018.021.

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5

Shemesh, J. "MS10.02 Coronary Artery Diseases." Journal of Thoracic Oncology 14, no. 10 (October 2019): S172—S173. http://dx.doi.org/10.1016/j.jtho.2019.08.344.

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6

Talarico, Giovanni P., Maria L. Crosta, Maria B. Giannico, Francesco Summaria, Leonardo Calò, and Roberto Patrizi. "Cocaine and coronary artery diseases." Journal of Cardiovascular Medicine 18, no. 5 (May 2017): 291–94. http://dx.doi.org/10.2459/jcm.0000000000000511.

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7

Zhou, Z., L. Xu, N. Zhang, H. Wang, W. Liu, Z. Sun, and Z. Fan. "CT coronary angiography findings in non-atherosclerotic coronary artery diseases." Clinical Radiology 73, no. 2 (February 2018): 205–13. http://dx.doi.org/10.1016/j.crad.2017.07.007.

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8

Fuller, Stephanie, and Chitra Ravishankar. "Acquired and Congenital Coronary Artery Diseases." Pediatric Critical Care Medicine 17 (August 2016): S356—S361. http://dx.doi.org/10.1097/pcc.0000000000000816.

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9

Ikeda, Uichi, and Kazuyuki Shimada. "Matrix metalloproteinases and coronary artery diseases." Clinical Cardiology 26, no. 2 (February 2003): 55–59. http://dx.doi.org/10.1002/clc.4960260203.

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10

Rahman, Zaheedur, Md Fakhrul Alam, and Israt Jahan. "Association of Hypertension and Coronary Heart Diseases." KYAMC Journal 12, no. 1 (May 8, 2021): 44–47. http://dx.doi.org/10.3329/kyamcj.v12i1.53368.

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Background: Hypertension is one and the major non-transferable diseases in the world and contributing altogether to the burden of cardiovascular diseases, stroke, kidney failure, and premature death. The association of hypertension and coronary heart disease is a very frequent one. Just 11% of the total instances of hypertension have compelling control of circulatory strain. Objective: The main goal of this study is to assess the association between hypertension and coronary heart diseases. Materials and Methods:A prospective observational study was conducted in a total of 300 patients from January 2016 to July 2016 in a single institution (Private hospital) in Dhaka, Bangladesh. The incidence of hypertension, its control, and association with coronary heart diseases was analysed in the patients. Results: In our investigation, the outcomes demonstrated that hypertension is highly associated with cardiovascular diseases in patients above 50 years old (p=0.001). A total of 228 patients in the study had hypertension and 30 were recently recognized. 63% of the patients with hypertension have viable control of blood pressure with medications and systolic hypertension was revealed in 6% cases. Conclusion: Hypertension and its treatment are related to coronary heart diseases. Treatment should be meant to achieve optimal values of blood pressure, and all the methodologies to treat coronary heart diseases should be considered on an individual premise. KYAMC Journal.2021;12(1): 44-47

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Balouch, Iram Jehan, Iftikhar Ahmed, Faiza Farooq, Syed Ahsan Raza, Najia Aslam Soomro, Muhammd Nauman Khan, Jawaid Akbar Sial, and Musa Karim. "PATTERN OF CORONARY ARTERY DISEASES IN PATIENTS UNDER 40 YEARS OF AGE WITH ACUTE CORONARY SYNDROME." Pakistan Heart Journal 54, no. 2 (June 24, 2021): 144–47. http://dx.doi.org/10.47144/phj.v54i2.2089.

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Objectives: To determine the pattern of coronary artery diseases (CAD) in patients under 40 years of age with acute coronary syndrome (ACS) presenting at Hyderabad Satellite Center of National Institute of Cardiovascular Disease (NICVD), Pakistan. Methodology: This cross-sectional study was conducted at cardiology department of the NICVD, Hyderabad Satellite Center. Both male and female patients, between 18 to 40 years of age, diagnosed with acute coronary syndrome (ACS), and undergone coronary angiography were included in this study. Angiographic patterns in terms of extent of the disease (number of diseased vessels and localization of lesion) were assessed. Results: Total of 220 young patients included. Patients were predominantly male (91.8%) with the mean age of 35.3 ± 5 years. Smoking was observed 30.5% followed by hypertension (24.5%) and positive family history of CAD (19.1%). A majority of the patients (79.1%) were diagnosed as with ST-elevation myocardial infarction (STEMI) with anterior wall myocardial infarction (MI) as the most common (57.3%) type of MI. Most of the patients (70%) had single vessel diseases (SVD) with left anterior descending artery (LAD) as the most commonly diseases vessel (53.6%). Nine (4.1%) patients had significant left main disease and 6.4% had non-obstructive CAD. Conclusion: The common clinical presentation of ACS in younger patients is STEMI. Smoking is the commonest risk factor followed by hypertension and family history of CAD. More than 2/3rd of the young patients are expected to have single vessel diseases with LAD as the most commonly diseased vessel.

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12

Kromhout, Daan. "Epidemiology of cardiovascular diseases in Europe." Public Health Nutrition 4, no. 2b (April 2001): 441–57. http://dx.doi.org/10.1079/phn2001133.

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AbstractWithin Europe large differences exist in mortality from coronary heart disease and stroke. These diseases show a clear West-East gradient with high rates in Eastern Europe. In spite the decreasing trend in age-adjusted cardiovascular disease mortality in Western European countries an increase in the number of cardiovascular patients is expected because of the ageing of the population. Consequently the health care cost for these diseases will increase.Total and HDL cholesterol are major determinants of coronary heart disease. Saturated and trans fatty acids have a total and LDL cholesterol elevating effect and unsaturated fatty acids a lowering effect. N-3 polyunsaturated fatty acids seem to have a protective effect on coronary heart disease occurrence independent of their effect on cholesterol.Dietary antioxidants could be of importance because they may prevent oxidation of the atherogenic cholesterol rich LDL lipoproteins. There is however no convincing evidence that either vitamin E, carotenoids or vitamin C protect against coronary heart disease. Observational research has shown that flavonols, polyphenols with strong antioxidant properties present in plant foods, may protect against coronary heart disease.Blood pressure is a major determinant of coronary heart disease and stroke. Historically salt is viewed as the most important dietary determinant of blood pressure. Recent research shows that also a low-fat diet rich in potassium, calcium and magnesium lowers blood pressure substantially. This suggests a multifactorial influence of different nutrients on blood pressure.It can be concluded that a diet low in saturated and trans fatty acids and rich in plant foods in combination with regular fish consumption is associated with a low risk of cardiovascular mortality.

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13

Malaguarnera, Michele, Marco Vacante, Cristina Russo, Giulia Malaguarnera, Tijana Antic, Lucia Malaguarnera, Rita Bella, Giovanni Pennisi, Fabio Galvano, and Alessandro Frigiola. "Lipoprotein(a) in Cardiovascular Diseases." BioMed Research International 2013 (2013): 1–9. http://dx.doi.org/10.1155/2013/650989.

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Lipoprotein(a) (Lp(a)) is an LDL-like molecule consisting of an apolipoprotein B-100 (apo(B-100)) particle attached by a disulphide bridge to apo(a). Many observations have pointed out that Lp(a) levels may be a risk factor for cardiovascular diseases. Lp(a) inhibits the activation of transforming growth factor (TGF) and contributes to the growth of arterial atherosclerotic lesions by promoting the proliferation of vascular smooth muscle cells and the migration of smooth muscle cells to endothelial cells. Moreover Lp(a) inhibits plasminogen binding to the surfaces of endothelial cells and decreases the activity of fibrin-dependent tissue-type plasminogen activator. Lp(a) may act as a proinflammatory mediator that augments the lesion formation in atherosclerotic plaques. Elevated serum Lp(a) is an independent predictor of coronary artery disease and myocardial infarction. Furthermore, Lp(a) levels should be a marker of restenosis after percutaneous transluminal coronary angioplasty, saphenous vein bypass graft atherosclerosis, and accelerated coronary atherosclerosis of cardiac transplantation. Finally, the possibility that Lp(a) may be a risk factor for ischemic stroke has been assessed in several studies. Recent findings suggest that Lp(a)-lowering therapy might be beneficial in patients with high Lp(a) levels. A future therapeutic approach could include apheresis in high-risk patients in order to reduce major coronary events.

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Breddin, Hans Klaus. "Antiplatelet Agents in Cardiovascular and Cerebrovascular Diseases." Clinical and Applied Thrombosis/Hemostasis 4, no. 2 (April 1998): 87–95. http://dx.doi.org/10.1177/107602969800400203.

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Aspirin has become a widely accepted platelet function inhibitor and is used to prevent arterial occlusions in coronary cerebral and peripheral vascular disease. The results of clinical studies with aspirin in the area of peripheral arterial occlusive disease are critically reviewed. Two thienopyridine compounds, ticlopidine and clopidogrel, have been effectively used in the prevention of myocardial infarction and stroke in several clinical trials, especially in the recently published CAPRIE-trial. Potent new platelet function inhibitors recently were developed. Intravenous treatment with abciximab, a new platelet membrane glycoprotein IIb/IIIa-inhibitor, effectively prevented coronary reocclusions in patients with high-risk coronary events. A series of promising new oral IIb/IIIa- inhibitors have been developed and may become effective drugs in the prevention of reocclusions in patients with periph eral vascular disease and in coronary or cerebral vascular dis ease. Key Words: Antiplatelet agents—Aspirin—Peripheral arterial disease—Ticlopidine—Clopidogrel—GPIIb/IIIa inhibitor.

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15

Kazelian, Lucía. "Autoimmune Diseases Promoting Coronary Disease in Women." Revista Argentina de Cardiología 81, no. 4 (August 2013): 330–34. http://dx.doi.org/10.7775/rac.v81.i4.2890.

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16

Maskell, Perry, Shwe Oo, Andrew D. Muir, Ka Siu Fan, and Amer Harky. "Techniques and approaches for revascularisation of left heart coronary diseases." British Journal of Hospital Medicine 81, no. 8 (August 2, 2020): 1–11. http://dx.doi.org/10.12968/hmed.2020.0067.

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Coronary artery disease and its associated clinical sequelae are a significant medical burden to clinicians and patients. Severe coronary artery disease presenting in the context of acute myocardial ischaemia, or stable plaques causing chronic symptoms despite best conservative and pharmacological intervention, are often amenable to further intervention such as coronary artery bypass grafting. This procedure has been extensively compared to newer and less invasive techniques, such as percutaneous coronary intervention, and other minimally invasive procedures such as robotic or endoscopic techniques. This review summarises the current evidence on revascularisation of the left coronary artery system, with particular emphasis on key clinical endpoints of mortality, myocardial infarction, stroke and repeat revascularisation.

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17

Вардиков, D. Vardikov, Яковлева, and E. Yakovleva. "Diagnostic Possibilities of Multislice Spiral Computed Tomography Coronary Angiography in Diseases of Coronary Arteries." Journal of New Medical Technologies 21, no. 4 (October 8, 2014): 44–48. http://dx.doi.org/10.12737/7267.

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In the Russian Federation, the death rate from cardiovascular disease is more than 56%. The main reason is atherosclerotic coronary artery disease, which leads to the development of coronary heart disease, and myocardial infarction. In the past, the only way to accurately diagnose coronary heart disease was invasive coronary angiography. This technique is deservedly referred to as the "gold standard" due to its high information content. However, coronary angiography is associated with the necessity of hospitalization in a hospital, as well as possible complications inherent in any invasive procedure. Having been in clinical practice multislice computed tomography has opened opportunities for the study of minimally invasive coronary artery status in patients with suspected coronary heart disease. The purpose of this work is to determine the diagnostic possibilities and optimization techniques of multi-detector computed tomographic coronary angiography. The study involved 38 patients with atherosclerotic coronary arteries, anomalies of the coronary arteries, and patients after stenting. The study was performed on a 64-slice “Aquilion 64” and 320-slice “Aquilion One” Toshiba computed tomographic machines. Analysis of the results of multi detector computed tomographic coronary angiography showed high diagnostic information value of this method in the assessment of coronary disease, in determining the type of blood supply distributed by the heart, in the visualization of the peripheral regions of the coronary arteries, and in the assessment of stents. Multi detector com-puted tomographic coronary angiography with 320-slice computed tomographic machine with one volume scan, shows a significant reduction of radiation exposure on the patient.

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18

Godo, Shigeo, Jun Takahashi, Satoshi Yasuda, and Hiroaki Shimokawa. "Endothelium in Coronary Macrovascular and Microvascular Diseases." Journal of Cardiovascular Pharmacology 78, no. 6S (December 2021): S19—S29. http://dx.doi.org/10.1097/fjc.0000000000001089.

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19

Kwon, Hyuck Moon. "Adventitial Vasa Vasorum in Coronary Artery Diseases." Korean Circulation Journal 28, no. 2 (1998): 309. http://dx.doi.org/10.4070/kcj.1998.28.2.309.

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20

Tabatabaee, A., MR Asharin, MH Dehghan, MR Pourbehi, M. Nasiri-Ahmadabadi, and M. Assadi. "Retinal vessel abnormalities predict coronary artery diseases." Perfusion 28, no. 3 (January 15, 2013): 232–37. http://dx.doi.org/10.1177/0267659112473173.

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21

Balta, S., S. Demirkol, Z. Arslan, T. Celik, M. Unlu, and A. Iyisoy. "Retinal vessel abnormalities and coronary artery diseases." Perfusion 28, no. 5 (April 23, 2013): 465. http://dx.doi.org/10.1177/0267659113485874.

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22

Ghilain, J.-M., A. Parfonry, V. Kozyreff, and F. R. Heller. "LIPOPROTEIN(a), CHOLESTEROL, AND CORONARY HEART DISEASES." Lancet 332, no. 8617 (October 1988): 963. http://dx.doi.org/10.1016/s0140-6736(88)92630-x.

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23

Fan, Yong, Yong Li, Yan Chen, Yi-Jing Zhao, Li-Wei Liu, Jin Li, Shi-Lei Wang, et al. "Comprehensive Metabolomic Characterization of Coronary Artery Diseases." Journal of the American College of Cardiology 68, no. 12 (September 2016): 1281–93. http://dx.doi.org/10.1016/j.jacc.2016.06.044.

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24

Ogami, Masayuki, Yoshihiro Ikura, Masahiko Ohsawa, Toshihiko Matsuo, Soichiro Kayo, Noriko Yoshimi, Eishu Hai, et al. "Telomere Shortening in Human Coronary Artery Diseases." Arteriosclerosis, Thrombosis, and Vascular Biology 24, no. 3 (March 2004): 546–50. http://dx.doi.org/10.1161/01.atv.0000117200.46938.e7.

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25

Naumova, O. A., L. A. Efros, and O. F. Kalev. "Prevalence of digestive diseases in patients with acute coronary syndrome." Experimental and Clinical Gastroenterology, no. 6 (August 4, 2020): 88–94. http://dx.doi.org/10.31146/1682-8658-ecg-178-6-88-94.

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Purpose of the study. To study the prevalence of digestive diseases in patients with acute coronary syndrome.Materials and methods. A retrospective study included 1079 patients with acute coronary syndrome who were treated in the cardiology department No. 2 of the Chelyabinsk Regional Clinical Hospital in 2015. After further examination, the diagnosis of acute coronary syndrome was withdrawn in 40 patients (3.7%). In the future, this group was not studied due to the small number of patients. Of the group of patients with acute coronary syndrome (n = 1039 people), patients were distributed taking into account gender and age, of which 679 (65.4%) were men, 360 (34.6%) were women. The average age of all patients was (61.9 ± 11.9) years, men (58.9 ± 11.9) years, women (67.6 ± 12.0) years. Statistical analysis was performed using Microsoft Offi ce applications and SPSS Statistics programs (version 21.0).Results. Among all concomitant diseases in patients with acute coronary syndrome, digestive diseases take the third place. Among the risk factors in patients with acute coronary syndrome and digestive diseases, hypertension and hypercholesterolemia were most often recorded. Multivascular damage to the coronary arteries was more often observed in patients with myocardial infarction in the presence of digestive diseases. At the time of discharge from the hospital in patients with acute coronary syndrome in the presence of diseases of the gastroduodenal zone, monotherapy (clopidogrel / ticagrelor) was recommended three times more often in comparison with the group without digestive diseases. Inhibitors of the proton pump (omeprazole) in the presence of pathology of the digestive system are recommended in almost 100% of cases, regardless of the clinical form of acute coronary syndrome.

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Dimkovic, Nada. "Cardiovascular diseases in patients with chronic renal diseases." Srpski arhiv za celokupno lekarstvo 136, Suppl. 2 (2008): 135–41. http://dx.doi.org/10.2298/sarh08s2135d.

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The risk of cardiovascular disease in patients with chronic renal disease appears to be far greater than in the general population and the risk of cardiovascular death is much higher than the risk of eventually requiring renal replacement therapy. Heart failure is important finding and it is evident even before the initiation of dialysis; the frequency of heart failure is 10 to 30 times higher in patients on dialysis than in the general population. Left ventricular hypertrophy has incidence of nearly 75-80% and is closely related to heart failure, ventricular arrhythmias, fatal myocardial infarction, aortic root dilatation and cerebrovascular event. Ischaemic heart disease is usually the consequence of coronary artery disease, but 27% of haemodialysis patients may have symptoms without atherosclerotic changes in coronary arteries. Silent myocardial ischemia is more frequent in dialysis population. Hypertension is present in 80-85% of patients and its prevalence is linearly related to glomerular filtration rate. Patients with end-stage renal disease are more likely to have an increase in pulse pressure and isolated systolic hypertension and they may not demonstrate the normal nocturnal decline in blood pressure. Patients on dialysis are prone to calcification of media and intima due to disbalance of promoters and inhibitors of calcification process. Now, there are no valid data about the privilege of one dialysis method over another in cardiovascular morbidity and mortality. Numerous traditional and non-traditional risk factors urge for preventive measures for cardiovascular diseases in patients with chronic renal diseases.

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27

Pluta, Kinga, Kinga Porębska, Tomasz Urbanowicz, Aleksandra Gąsecka, Anna Olasińska-Wiśniewska, Radosław Targoński, Aleksandra Krasińska, Krzysztof J. Filipiak, Marek Jemielity, and Zbigniew Krasiński. "Platelet–Leucocyte Aggregates as Novel Biomarkers in Cardiovascular Diseases." Biology 11, no. 2 (January 30, 2022): 224. http://dx.doi.org/10.3390/biology11020224.

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Platelet–leucocyte aggregates (PLA) are a formation of leucocytes and platelets bound by specific receptors. They arise in the condition of sheer stress, thrombosis, immune reaction, vessel injury, and the activation of leukocytes or platelets. PLA participate in cardiovascular diseases (CVD). Increased levels of PLA were revealed in acute and chronic coronary syndromes, carotid stenosis cardiovascular risk factors. Due to accessible, available, replicable, quick, and low-cost quantifying using flow cytometry, PLA constitute an ideal biomarker for clinical practice. PLA are promising in early diagnosing and estimating prognosis in patients with acute or chronic coronary syndromes treated by percutaneous coronary intervention (PCI) and coronary artery bypass grafting (CABG). PLA were also a reliable marker of platelet activity for monitoring antiplatelet therapy. PLA consist also targets potential therapies in CVD. All of the above potential clinical applications require further studies to validate methods of assay and proof clinical benefits.

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Arnold, Csaba, Zoltán Englert, Csaba Szabadhegyi, and Csaba Farsang. "Digital risk analysis of cardiovascular diseases: new opportunities for the patients." Orvosi Hetilap 149, no. 15 (April 2008): 677–84. http://dx.doi.org/10.1556/oh.2008.28353.

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Authors constructed a software helping the prevention programme of coronary and vascular diseases as the classical risk factors are used for graphic presentation of coronary risk as compared to “normal” risk. By repeated estimation alterations in coronary risk status can be compared to previous ones and thereby help evaluating the changes. This programme is highlighted by the presentation of changes in coronary risk of a patient during a 4-year-long period of her medical history. It is also shown how graphic presentation of risk can support the more effective treatment and patient care.

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Choudhury, Arup Ratan, Kamrun Nahar Choudhury, and Sheikh Mohammed Shariful Islam. "Relationship of dental diseases with coronary artery diseases and diabetes in Bangladesh." Cardiovascular Diagnosis and Therapy 6, no. 2 (April 2016): 131–37. http://dx.doi.org/10.21037/cdt.2016.02.05.

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30

Panteghini, Mauro. "Biochemical markers of cardiac diseases." Jugoslovenska medicinska biohemija 23, no. 3 (2004): 201–11. http://dx.doi.org/10.2298/jmh0403201p.

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This article reviews the current contribution of the determination of biochemical markers to clinical cardiology and discusses some important developments in this field. Biochemical markers play a pivotal role in the diagnosis and management of patients with acute coronary syndrome (ACS), as witnessed by the incorporation of cardiac troponins into new international guidelines for patients with ACS and in the redefinition of myocardial infarction. Despite the success of cardiac troponins, there is still a need for development of early markers that can reliably rule out ACS from the emergency room at presentation and detect myocardial ischemia also in the absence of irreversible myocyte injury. Under investigation are two classes of indicators: markers of early injury/ischemia and markers of coronary plaque instability and disruption. Finally, with the characterization of the cardiac natriuretic peptides, Laboratory Medicine is also assuming part in the assessment of cardiac function.

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Мустафина, М. О., А. Телжанов, and З. Н. Лигай. "CARDIOVASCULAR DISEASES: PREVALENCE, RISK FACTORS (LITERATURE REVIEW)." Vestnik, no. 2 (June 25, 2021): 84–92. http://dx.doi.org/10.53065/kaznmu.2021.91.74.014.

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Мы провели поиск в PubMed статей, опубликованных с 1980 по 2020, используя термины «острый инфаркт миокарда», «молодой», «разрыв бляшки», эрозия бляшки, спонтанное расслоение коронарной артерии (SCAD), коронарный вазоспазм», «вариантная стенокардия или стенокардия Принцметала», «лекарственный инфаркт миокарда», «миокардит», «коронарная эмболия», «микрососудистая дисфункция», «MINOCA», а также обзор всех опубликованных исследований. Используя данные этого поиска, мы стремимся проинформировать читателей о распространенности, факторах риска, проявлениях и лечении острого инфаркта миокарда у молодых пациентов, а также подробно рассказать о специальных подгруппах с диагностическими и терапевтическими проблемами. We searched PubMed for articles published from 1980 to 2020 using the terms acute myocardial infarction, young, plaque rupture, plaque erosion, spontaneous coronary artery dissection (SCAD), coronary vasospasm, variant angina or angina pectoris. Prinzmetal, drug myocardial infarction, myocarditis, coronary embolism, microvascular dysfunction, MINOCA, and a review of all published studies. Using the data from this search, we aim to inform readers about the prevalence, risk factors, manifestations and treatment of acute myocardial infarction in young patients, as well as detail the special subgroups with diagnostic and therapeutic problems.

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Bergquist, Jonas, Gökhan Baykut, Maria Bergquist, Matthias Witt, Franz-Josef Mayer, and Doan Baykut. "Human Myocardial Protein Pattern Reveals Cardiac Diseases." International Journal of Proteomics 2012 (August 8, 2012): 1–17. http://dx.doi.org/10.1155/2012/342659.

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Proteomic profiles of myocardial tissue in two different etiologies of heart failure were investigated using high performance liquid chromatography (HPLC)/Fourier transform ion cyclotron resonance mass spectrometry (FT-ICR MS). Right atrial appendages from 10 patients with hemodynamically significant isolated aortic valve disease and from 10 patients with isolated symptomatic coronary heart disease were collected during elective cardiac surgery. As presented in an earlier study by our group (Baykut et al., 2006), both disease forms showed clearly different pattern distribution characteristics. Interesting enough, the classification patterns could be used for correctly sorting unknown test samples in their correct categories. However, in order to fully exploit and also validate these findings there is a definite need for unambiguous identification of the differences between different etiologies at molecular level. In this study, samples representative for the aortic valve disease and coronary heart disease were prepared, tryptically digested, and analyzed using an FT-ICR MS that allowed collision-induced dissociation (CID) of selected classifier masses. By using the fragment spectra, proteins were identified by database searches. For comparison and further validation, classifier masses were also fragmented and analyzed using HPLC-/Matrix-assisted laser desorption ionization (MALDI) time-of-flight/time-of-flight (TOF/TOF) mass spectrometry. Desmin and lumican precursor were examples of proteins found in aortic samples at higher abundances than in coronary samples. Similarly, adenylate kinase isoenzyme was found in coronary samples at a higher abundance. The described methodology could also be feasible in search for specific biomarkers in plasma or serum for diagnostic purposes.

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Ermakova, M. A., and A. Yu Pinigina. "Genetic studies in multifactorial diseases." Glavvrač (Chief Medical Officer), no. 12 (December 10, 2022): 36–40. http://dx.doi.org/10.33920/med-03-2212-06.

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This article is devoted to the role of gene mutations in the development of multifactorial diseases such as arterial hypertension, coronary heart disease, and cancer, as well as to genotyping in optimizing the prevention, early diagnosis, and treatment of various pathologies in children and young people.

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Haque, Nadira, Nazmul Hosain, AKM Monwarul Islam, Zakia Mamataz, Md Ibrahim, Shamim Ahmed, Md Anisuzzaman, and Shahena Akter. "Coronary Artery Diseases During Pregnancy: Minimizing Adverse Consequences and Improving Clinical Outcome." Cardiovascular Journal 14, no. 1 (September 15, 2021): 61–69. http://dx.doi.org/10.3329/cardio.v14i1.55376.

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Coronary artery disease in pregnancy is a catastrophic situation that may endanger the lives of both the mother and the fetus. Cardiac diseases may account for up to 15% of maternal mortality. Pregnancy may increase the risk of acute myocardial infarction up to 4-fold. Various hemodynamic derangements may occur during pregnancy including expansion of plasma and blood volume, compression of inferior vena cava and fall in both systemic and pulmonary vascular resistances. If pregnant women present with acute coronary artery disease, medical management should be attempted first and if any intervention or surgery is needed, efforts must be made to lower the risk. A multidisciplinary approach is essential involving obstetrician, cardiologist, cardiac surgeons, anesthesiologist and neonatologists or pediatrician. Pregnancy is considered to be a relative contraindication to thrombolytic therapy due to some complications. Revascularization may be considered in acute coronary syndrome in pregnant women like other nonpregnant patients. Primary per cutaneous coronary intervention or coronary artery bypass graft have been performed successfully during pregnancy and may be considered as therapeutic option in pregnancy in selective cases. Percutaneous coronary intervention (PCI) is considered to be relatively safe for maternal and fetal survival during pregnancy. Main worry in PCI is radiation exposure and need to dual antiplatelet therapy. Bare metal stent is preferred during pregnancy because of shorter duration of anticoagulation therapy. Early second trimester is the optimum surgical period to coronary artery bypass surgery (CABG) in pregnant women. Coronary artery bypass surgery can be safely done after 28 weeks of gestational age and immediately after cesarean section. Early detection, a multidisciplinary approach and timely interventions must be considered in coronary artery disease in pregnancy for better obstetric outcome. Cardiovasc j 2021; 14(1): 61-69

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35

Volger, E. "Rheological aspects of coronary artery and coronary small blood vessel diseases (Syndrome X)." Clinical Hemorheology and Microcirculation 4, no. 2-3 (December 9, 2016): 209–21. http://dx.doi.org/10.3233/ch-1984-42-312.

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Miretti, E. M., L. Lema, M. Haye Salinas, V. Quino, M. V. Barroso, C. Serra, F. Caeiro, A. Alvarellos, and V. Saurit. "AB1047 Autoimmune Diseases in Patients with Acute Coronary Syndrome Subject to Coronary Angiography." Annals of the Rheumatic Diseases 73, Suppl 2 (June 2014): 1146.2–1147. http://dx.doi.org/10.1136/annrheumdis-2014-eular.1437.

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Aoyama, Norio, Naho Kobayashi, Tomoya Hanatani, Norihiko Ashigaki, Asuka Yoshida, Yuka Shiheido, Hiroki Sato, et al. "Periodontal condition in Japanese coronary heart disease patients: A comparison between coronary and non‐coronary heart diseases." Journal of Periodontal Research 54, no. 3 (November 18, 2018): 259–65. http://dx.doi.org/10.1111/jre.12626.

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Karimzadeh Ghassab, Romina. "Review of Ten Biomarkers of Coronary Artery Diseases." Focus on Sciences 2, no. 1 (February 1, 2016): 1–10. http://dx.doi.org/10.20286/focsci-020112.

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Tuzcu, E. M., D. S. Moodie, J. L. Chambers, P. Keyser, and R. E. Hobbs. "Congenital heart diseases associated with coronary artery anomalies." Cleveland Clinic Journal of Medicine 57, no. 2 (March 1, 1990): 147–52. http://dx.doi.org/10.3949/ccjm.57.2.147.

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Ahmad, Jamil, AKM Mustafa Kamal Pasha, Md Ziaul Islam, and SM Humayan Kabir. "Association of Smokeless Tobacco with Coronary Heart Diseases." Journal of Armed Forces Medical College, Bangladesh 14, no. 2 (March 10, 2020): 106–8. http://dx.doi.org/10.3329/jafmc.v14i2.45885.

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Introduction: Coronary heart diseases (CHDs) are one of the leading killers in our country. Both smoking and smokeless tobacco (SLT) are major risk factors for CHDs. Bangladesh is one of the top-ranked countries in the world regarding SLT users. Objectives: To determine the relation between smokeless tobacco uses and CHDs. Materials and Methods: This case-control observational study was conducted at the outpatientdepartment of Combined Military Hospital, Dhaka and National Institute of Cardiovascular Diseases and Hospital from July 2017 to June 2018 among selected 62 adultcoronary heart diseasepatients (Cases) and 62 age and sex-matched non-CHDs patients (Controls). Results: In Cases; 61.3% of respondents were male and mean age was 51.56 + 11.46 years. In Controls; 56.5 % respondents were male and mean age was 48.15 ± 12.53 years. Among the CHDs cases 19 (30.6%) was SLT users but in non-CHD cases it was only 10(16.1%) and this difference was not statistically significant. All the SLT users in CHDs Controlswere longduration users and majority uses Gul or Jorda. Conclusion: Number of SLT users was more in CHDs Cases than non-CHD Controls but this difference was not statistically significant. Further studies with more sample size are recommended to find the relation between SLT users and CHDS. Journal of Armed Forces Medical College Bangladesh Vol.14 (2) 2018: 106-108

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41

Chibuzo Carole Nweze, Eneh Williams Nebechukwu, and Muhammad Yusuf Bawa. "Dietary fiber and risk of coronary heart diseases." GSC Advanced Research and Reviews 9, no. 3 (December 30, 2021): 001–9. http://dx.doi.org/10.30574/gscarr.2021.9.3.0280.

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Dietary fiber is the portion of plant-derived food that cannot be completely broken down by human digestive enzymes. Dietary fibers can be grouped generally by their solubility, viscosity, and fermentation, which affect how fibers are processed in the body. Dietary fiber has two main components: soluble fiber and insoluble fiber, which are components of plant foods, such as legumes, whole grains and cereals, vegetables, fruits, and nuts or seeds. Consumption of cereals, vegetable and fruit may lower the risk of coronary heart disease. Coronary heart disease involves the reduction of blood flow to the heart muscle due to build-up of plaque on the arteries of the heart. Dietary fiber makes three primary contributions: bulking, viscosity and fermentation. The bulking effect of some fibers reduces constipation and the risk of colon disease because they absorb water, which increases bulking and promotes regularity. Viscosity effects on fibers reduce the absorption of cholesterol and other nutrients because of the formation of gels that attenuate postprandial blood glucose and lipid rises. The formation of gels also slows gastric emptying, maintaining levels of satiety and contributing towards less weight gain. In the fermentation process, the bacteria GIT helps to digest fiber through a process of microbial fermentation to generate short chain fatty acids like acetate, propionate and butyrate. Butyrate binds to G-protein coupled receptors on the brush borders of intestinal lining and trigger a signal cascade that release GLP-1 and PYY. These peptides behave like hormones to trigger satiety. One of the reasons for eating fiber rich foods is because they promote satiety and prevent uncontrollable quest for food. People that eat food low in fiber experience over feeding issues. When people over eat they consume more calories leading to weight gain and that contributes to obesity. Obesity is the accumulation of fats in fat tissues. Excess fats are converted to cholesterol (LDL) which accumulates on the walls of the arteries and prevent the flow of blood to the heart. This is prevented when an individual consumes foods rich in fiber.

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Takahashi, Masato. "Inflammatory diseases of the coronary artery in children." Coronary Artery Disease 4, no. 2 (February 1993): 133–38. http://dx.doi.org/10.1097/00019501-199302000-00003.

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Faccini, Alessia, Juan Carlos Kaski, and Paolo G. Camici. "Coronary microvascular dysfunction in chronic inflammatory rheumatoid diseases." European Heart Journal 37, no. 23 (February 23, 2016): 1799–806. http://dx.doi.org/10.1093/eurheartj/ehw018.

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Llaurado, J. G. "Coronary Artery Diseases: Diagnostic and Therapeutic Imaging Approaches." Clinical Nuclear Medicine 11, no. 8 (August 1986): 603. http://dx.doi.org/10.1097/00003072-198608000-00025.

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45

Stansfeld, S. "Depression and coronary heart diseases – An epidemiological perspective." Journal of Affective Disorders 107 (March 2008): S24. http://dx.doi.org/10.1016/j.jad.2007.12.156.

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Mirza, Ayoub. "Myocardial infarction resulting from nonatherosclerotic coronary artery diseases." American Journal of Emergency Medicine 21, no. 7 (November 2003): 578–84. http://dx.doi.org/10.1016/s0735-6757(03)00104-9.

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Singh, Seema, Syed Tahseen Raza, Nitin Ranjan Gupta, and Janhvi Verma. "ROLE OF miRNAs IN CORONARY ARTERY DISEASE: A MINI REVIEW." Era's Journal of Medical Research 7, no. 2 (December 2020): 217–19. http://dx.doi.org/10.24041/ejmr2020.36.

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While coronary artery disease (CAD) has become a major threat worldwide, early diagnosis of CAD, based on timely biomarkers, remains a major unmet clinical challenge. Micro-RNAs (miRNAs) play a pivotal role in development of the cardiovascularsystem while they are associated with multiple cardiovascular diseases. Several cardiac miRNAs (circulating miRNAs) are observable in circulation and function as biomarkers for CVDs diagnosis and therapy. C-miRNAs display various critical features as biomarkers although their distribution is incredibly stable in circulation; their expression is tissue-/diseasespecific and can be easily identified using sequence-specific amplification methods. Such circulating-miRNAs features are useful in designing non-invasive assays to track the development of CVDs. Given substantial success in serum and plasma identification of c-miRNAs. There are several conflicting studies on the alterations of circulating miRNAs concentration in circulation system. Measurements of microRNA (miRNA, miR) in patients with coronary heart disease are impeded by the confoundingeffects of medication commonly used in cardiovascularpatients.

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Belyalov, Farid I. "The use of scales in clinical practice. Part 1. Coronary heart disease." Clinical Medicine (Russian Journal) 94, no. 11 (January 10, 2017): 861–64. http://dx.doi.org/10.18821/0023-2149-2016-94-11-861-864.

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Scores for diagnosis, prediction and treatment cardiovascular diseases are discussed in the article. Advantages and limitations of popular scores for stable coronary artery diseases, acute coronary syndroms and risk of cardiovascular diseases in clinical practice are discussed.

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Keijo Koski, Pekka Laippala, Sirkka. "Predictors of coronary heart diseases among children and adolescents in families with premature coronary heart diseases in central eastern Finland." Scandinavian Journal of Primary Health Care 18, no. 3 (January 2000): 170–76. http://dx.doi.org/10.1080/028134300453386.

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Gloria-Bottini, F., M. Banci, P. Saccucci, N. Lucarini, F. Ianniello, G. Paradisi, A. Magrini, and E. Bottini. "Coronary Artery Disease: A Study on the Joint Role of Birth Weight, Adenosine Deaminase, and Gender." Cardiology Research and Practice 2009 (2009): 1–6. http://dx.doi.org/10.4061/2009/860328.

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An inverse relationship between birth weight and coronary artery diseases is well documented but it remains unclear which exposure in early life might underlie such association. Recently it has been reported an association between adenosine deaminase genetic polymorphism and coronary artery diseases. Gender differences in the degree of this association have been also observed. These observations prompted us to study the possible joint effects of BW, ADA, and gender on the susceptibility to coronary artery diseases. 222 subjects admitted to hospital for nonfatal coronary artery diseases, and 762 healthy consecutive newborns were studied. ADA genotypes were determined by DNA analysis. A highly significant complex relationship has emerged among ADA, birth weight, and gender concerning their role on susceptibility to coronary artery diseases in adult life. Odds ratio analysis suggests that low birth weight is more important in females than in males. ADA∗2 allele appears protective in males, while in females such effect is obscured by birth weight.

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