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Journal articles on the topic 'Coronary Elongation'

Author: Grafiati

Published: 3 June 2025

Last updated: 31 July 2025

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1

Novick, William M., Xiao F. Li, Darko Anic, et al. "Anomalous left coronary artery from the pulmonary artery: intermediate results of coronary elongation☆." Interactive CardioVascular and Thoracic Surgery 9, no. 5 (2009): 814–18. http://dx.doi.org/10.1510/icvts.2009.208215.

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2

Matsumura, A. "Impact of longitudinal stent elongation during percutaneous coronary intervention." European Heart Journal 34, suppl 1 (2013): P3030. http://dx.doi.org/10.1093/eurheartj/eht309.p3030.

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3

Matsumura, Akihiko. "Impact of Longitudinal Stent Elongation During Percutaneous Coronary Intervention." American Journal of Cardiology 111, no. 7 (2013): 25B. http://dx.doi.org/10.1016/j.amjcard.2013.01.067.

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4

Vogt, Pierre, Eric Eeckhout, Jean-Christophe Stauffer, Jean-Jacques Goy, and Lukas Kappenberger. "Stent shortening and elongation: Pitfalls with the wiktor coronary endoprosthesis." Catheterization and Cardiovascular Diagnosis 31, no. 3 (1994): 233–35. http://dx.doi.org/10.1002/ccd.1810310315.

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Baruah, Dibya Kumar, Anuradha Darimireddi, Ravikant Telikicherla, and Pedada Chakradhar. "Longitudinal Stent Elongation: A Rare Complication of Third-Generation Drug-eluting Stent Platform." Research in Cardiovascular Medicine 13, no. 1 (2024): 19–22. http://dx.doi.org/10.4103/rcm.rcm_72_23.

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Abstract Longitudinal stent deformation (LSD) is an infrequent complication of percutaneous coronary intervention. While the occurrence of gross LSD is a rare phenomenon, minor changes in length are common and have been recognized as accepted behavior of stents during implantation. Due to the proximity of the guide catheter, ostial or ostio-proximal lesions are prone to stent deformation either by the guide or other devices during navigation. Moreover, to satisfy the fractal geometry of coronary bifurcation, the proximal optimization technique is commonly performed during different bifurcation

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Matsumoto, Sen, Masayuki Sakakibara, and Nagahiro Nishikawa. "Longitudinal Stent Elongation of a Tapered Lesion during Percutaneous Coronary Intervention: A Case Report." International Journal of Angiology 28, no. 03 (2018): 200–201. http://dx.doi.org/10.1055/s-0038-1629919.

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AbstractThe therapeutic strategy for percutaneous coronary intervention (PCI) of a tapered lesion is still being developed. Herein, we describe a 67-year-old man with stable angina who underwent elective PCI of a tapered lesion. The coronary angiogram showed diffuse, severe stenosis in the tapered left anterior descending artery. A third-generation sirolimus-eluting stent (2.5 × 24-mm Ultimaster, Terumo, Tokyo, Japan) was deployed, and the distal side was selected as the reference. Postdilatation with a balloon diameter 2.0 mm larger than the stent was needed because of the tapered lesion. We

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Tarui, Suguru, Yoshinori Miyahara, Nobuo Oyama, Takanari Fujii, Kozo Ishino, and Hideshi Tomita. "Double-outlet extension for narrowed retroaortic space." Asian Cardiovascular and Thoracic Annals 28, no. 2 (2019): 123–25. http://dx.doi.org/10.1177/0218492319896497.

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In cyanotic congenital heart disease, an enlarged aorta often compresses the retroaortic space, resulting in pulmonary artery narrowing. We experienced a case of a 10-year-old boy with severe pulmonary artery stenosis resulting from a narrowed retroaortic space after a Rastelli operation. The right pulmonary artery was closely aligned with the left coronary artery, which made pulmonary artery stenting difficult. We performed surgical repair including aortic extension with an interposition graft and elongation of the right ventricular outflow tract (double-outlet extension). This procedure was

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8

Calafiore, A. "Left internal mammary elongation with inferior epigastric artery in minimally invasive coronary surgery." European Journal of Cardio-Thoracic Surgery 12, no. 3 (1997): 393–96. http://dx.doi.org/10.1016/s1010-7940(97)00182-6.

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9

Zheng, Wei, Lance P. Christensen, and Robert J. Tomanek. "Differential effects of cyclic and static stretch on coronary microvascular endothelial cell receptors and vasculogenic/angiogenic responses." American Journal of Physiology-Heart and Circulatory Physiology 295, no. 2 (2008): H794—H800. http://dx.doi.org/10.1152/ajpheart.00343.2008.

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Mechanical stretch, an important growth stimulus, results not only from pulsatile blood flow and diastolic stretch of the ventricles [cyclic stretch (CS)] but also from tissue expansion during growth [constant static stretch (SS)]. We compared growth factor receptor expression and vasculogenic/angiogenic responses of rat coronary microvascular endothelial cells (ECs) by exposing cells to CS (10% elongation at 30 cycles/min) and SS (constant 10% elongation). Both CS and SS increased VEGF receptor (VEGF-R)2 protein levels and the extent of tube formation and branching. Moreover, both CS and SS e

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10

Juzar, Dafsah Arifa, and Bayushi Eka Putra. "A Broken Heart Coexisting with Obstructive Coronary Artery Disease: Double Trouble." Indonesian Journal of Cardiology 43, no. 4 (2023): 168–73. http://dx.doi.org/10.30701/ijc.1368.

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Background. Takotsubo is a syndrome characterized by transient regional systolic dysfunction of the left ventricle (LV). The most common clinical presentation mimics acute myocardial infarction without angiographic evidence of obstructive coronary artery disease or acute plaque rupture.1-3 The diagnosis and management became a challenge when it presented as atypical symptoms and significant obstructive coronary artery. Thus, this case report highlights the diagnosis and management of Takotsubo Cardiomyopathy with obstructive coronary artery disease.Case illustration. A 71 years old woman came

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Yoshida, Hiroki, and Akihiko Matsumura. "TCTAP A-094 Assessment of Differences in Degree of Elongation Between Stents by Coronary CT Angiography." Journal of the American College of Cardiology 63, no. 12 (2014): S27. http://dx.doi.org/10.1016/j.jacc.2014.02.563.

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Yi, Xiu-Yu, Kathryn M. Gauthier, Lijie Cui, Kasem Nithipatikom, John R. Falck та William B. Campbell. "Metabolism of adrenic acid to vasodilatory 1α,1β-dihomo-epoxyeicosatrienoic acids by bovine coronary arteries". American Journal of Physiology-Heart and Circulatory Physiology 292, № 5 (2007): H2265—H2274. http://dx.doi.org/10.1152/ajpheart.00947.2006.

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Adrenic acid (docosatetraenoic acid), an abundant fatty acid in the vasculature, is produced by a two-carbon chain elongation of arachidonic acid. Despite its abundance and similarity to arachidonic acid, little is known about its role in the regulation of vascular tone. Gas chromatography/mass spectrometric analysis of bovine coronary artery and endothelial cell lysates revealed arachidonic acid concentrations of 2.06 ± 0.01 and 6.18 ± 0.60 μg/mg protein and adrenic acid concentrations of 0.29 ± 0.01 and 1.56 ± 0.16 μg/mg protein, respectively. In bovine coronary arterial rings preconstricted

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13

Sun, Fan, Thierry Gloriant, Philippe Vermaut, Pascal Jacques, and Frédéric Prima. "Beta Titanium Alloys with Very High Ductility Induced by Complex Deformation Mechanisms: a New Material Perspective for Coronary Stent Applications." Solid State Phenomena 172-174 (June 2011): 129–34. http://dx.doi.org/10.4028/www.scientific.net/ssp.172-174.129.

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The increased use of metallic biomaterials in contact with blood e.g. for application as coronary stents is steadily resulting in the development of new biomaterials. Conventional bare-metal stents made by stainless steel were reported on adverse reactions against human body and are gradually replaced by coated stainless steel. The new generation of stent requires fundamental improvements at the materials point of view. Although titanium and classical Ti-alloys display superior biocompatibility compared to other metallic materials (stainless steels, Co-Cr), the major drawback of their relative

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Zimmerman, Scott D., John Criscione, and James W. Covell. "Remodeling in myocardium adjacent to an infarction in the pig left ventricle." American Journal of Physiology-Heart and Circulatory Physiology 287, no. 6 (2004): H2697—H2704. http://dx.doi.org/10.1152/ajpheart.00160.2004.

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Changes in the structure of the “normal” ventricular wall adjacent to an infarcted area involve all components of the myocardium (myocytes, fibroblasts and the extracellular matrix, and the coronary vasculature) and their three-dimensional structural relationship. Assessing changes in these components requires tracking material markers in the remodeling tissue over long periods of time with a three-dimensional approach as well as a detailed histological evaluation of the remodeled structure. The purpose of the present study was to examine the hypotheses that changes in the tissue adjacent to a

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15

Kim, Oh, Su Lee, and Won An. "Impact of Blood or Erythrocyte Membrane Fatty Acids for Disease Risk Prediction: Focusing on Cardiovascular Disease and Chronic Kidney Disease." Nutrients 10, no. 10 (2018): 1454. http://dx.doi.org/10.3390/nu10101454.

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Fatty acids (FAs) are essential nutrients and main constituents of cell membranes that are involved in the signaling pathway and associated with health conditions. We investigated if blood or erythrocyte membrane FAs can predict the risk of cardiovascular disease (CVD), chronic kidney disease (CKD), and related complications. Omega-3 (n-3) FAs are important predictors for metabolic syndrome, diabetes, CVD, and CKD risks, and the n-3 index is also a good biomarker for sudden cardiac death in coronary artery disease. Linoleic acid, which is one of the major n-6 FAs reflecting recent dietary FA i

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16

Pramanik, Sudipta, Dennis Milaege, Maxwell Hein, Kay-Peter Hoyer, and Mirko Schaper. "Additive Manufacturing and Mechanical Properties of Auxetic and Non-Auxetic Ti24Nb4Zr8Sn Biomedical Stents: A Combined Experimental and Computational Modelling Approach." Crystals 13, no. 11 (2023): 1592. http://dx.doi.org/10.3390/cryst13111592.

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The effect of plaque deposition (atherosclerosis) on blood flow behaviour is investigated via computational fluid dynamics and structural mechanics simulations. To mitigate the narrowing of coronary artery atherosclerosis (stenosis), the computational modelling of auxetic and non-auxetic stents was performed in this study to minimise or even avoid these deposition agents in the future. Computational modelling was performed in unrestricted (open) conditions and restricted (in an artery) conditions. Finally, stent designs were produced by additive manufacturing, and mechanical testing of the ste

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17

Vivekanantham, Hari, Stéphane Cook, and Jean-Christophe Stauffer. "An incidental finding of a bicuspid aortic valve and pseudocoarctation of the descending aorta in a patient presenting with an acute coronary syndrome: a case report." European Heart Journal - Case Reports 4, no. 3 (2020): 1–5. http://dx.doi.org/10.1093/ehjcr/ytaa105.

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Abstract Background Aortic pseudocoarctation (PsCoA) is an elongation of the supra-isthmic aorta with kinking and low-grade narrowing. Consequently, no collateral circulation is found. It is frequently associated with other congenital heart anomalies, such as bicuspid aortic valve (BAV). Case summary We report the case of 60-year-old patient who presented to the ED with acute chest pain. Physical examination was remarkable for an elevated blood pressure (BP) and the presence of a systolic murmur on the left lower sternal border. An acute coronary syndrome was suspected and the patient underwen

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18

Hrabak Paar, Maja, Miroslav Muršić, Jens Bremerich, and Tobias Heye. "Cardiovascular Aging and Risk Assessment: How Multimodality Imaging Can Help." Diagnostics 14, no. 17 (2024): 1947. http://dx.doi.org/10.3390/diagnostics14171947.

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Aging affects the cardiovascular system, and this process may be accelerated in individuals with cardiovascular risk factors. The main vascular changes include arterial wall thickening, calcification, and stiffening, together with aortic dilatation and elongation. With aging, we can observe left ventricular hypertrophy with myocardial fibrosis and left atrial dilatation. These changes may lead to heart failure and atrial fibrillation. Using multimodality imaging, including ultrasound, computed tomography (CT), and magnetic resonance imaging, it is possible to detect these changes. Additionally

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19

Kanemaru, Yusuke, Yuichiro Arima, Koichi Kaikita, et al. "Elongation of the high right atrium to coronary sinus conduction time predicts the recurrence of atrial fibrillation after radiofrequency catheter ablation." International Journal of Cardiology 300 (February 2020): 147–53. http://dx.doi.org/10.1016/j.ijcard.2019.10.044.

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20

Jugdutt, B. I. "Effect of reperfusion on ventricular mass, topography, and function during healing of anterior infarction." American Journal of Physiology-Heart and Circulatory Physiology 272, no. 3 (1997): H1205—H1211. http://dx.doi.org/10.1152/ajpheart.1997.272.3.h1205.

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The effect of reperfusion performed 2 h after left anterior descending coronary artery occlusion on in vivo changes (echocardiograms) in ventricular mass, topography, and function during postinfarction healing over 6 wk and postmortem topography (planimetry) and collagen (hydroxyproline) content at 6 wk were measured in dogs randomized to reperfusion (n = 12) and no reperfusion (n = 12). Compared with no reperfusion over the 6 wk, reperfusion resulted in less increase in systolic and diastolic volumes, less increase in ventricular mass, less infarct wall thinning, and mild improvement in globa

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Carmona, Carlos A., Fatma Levent, Kelvin Lee, and Bhavya Trivedi. "Atrioventricular Conduction Abnormalities in Multisystem Inflammatory Syndrome in Children." Case Reports in Pediatrics 2021 (October 1, 2021): 1–7. http://dx.doi.org/10.1155/2021/6124898.

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Cardiac manifestations in multisystem inflammatory syndrome in children (MIS-C) can include coronary artery aneurysms, left ventricular systolic dysfunction, and electrocardiographic disturbances. We report the clinical course of three children with MIS-C while focusing on the unique considerations for managing atrioventricular conduction abnormalities. All initially had normal electrocardiograms but developed bradycardia followed by either PR prolongation or QTc elongation. Two had mild left ventricular ejection fraction dysfunction prior to developing third-degree heart block and/or a juncti

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22

Song, Zikai, Hongyan Cao, Ling Qin, and Yanfang Jiang. "A Case-Control Study between Gene Polymorphisms of Polyunsaturated Fatty Acid Metabolic Rate-Limiting Enzymes and Acute Coronary Syndrome in Chinese Han Population." BioMed Research International 2013 (2013): 1–7. http://dx.doi.org/10.1155/2013/928178.

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The purpose of this study is to analyze the relationship between the polymorphisms of fatty acid desaturase 1 (FADS1), fatty acid desaturase 2 (FADS2), and elongation of very long-chain fatty acids-like 2 (ELOVL2) and acute coronary syndrome (ACS) in Chinese Han population. Therefore, we selected three single nucleotide polymorphisms (SNPs) from these candidate genes and genotyped them using PCR-based restriction fragment length polymorphism analysis in 249 ACS patients and 240 non-ACS subjects, as were Han Chinese ancestry. The results showed that rs174556 in theFADS1 gene is found to be in a

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23

Levine, Jami C., Stephen P. Sanders, Steven D. Colan, Richard A. Jonas, and Philip J. Spevak. "The risk of having additional obstructive lesions in neonatal coarctation of the aorta." Cardiology in the Young 11, no. 1 (2001): 44–53. http://dx.doi.org/10.1017/s1047951100012415.

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AbstractInfants with coarctation of the aorta may have obstructions at other sites within the left heart which are not always apparent on the initial echocardiogram. The magnitude of the risk of having the additional obstructions is not well described, with few reliable quantitative criterions for identifying patients at the highest risk. We determined the frequency of additional, late appearing, stenotic lesions within the left heart, and the predictive morphologic features on the initial cross-sectional echocardiogram.We identified all patients with coarctation of the aorta diagnosed by 3 mo

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Mlachkova, Antoaneta, and Zdravka Pashova-Tasseva. "Treatment of Gingival Recessions Class II Miller in Lower Jaw with Coronary Advanced Flap and Connective Tissue Graft-Case Report." Balkan Journal of Dental Medicine 24, no. 3 (2020): 60–64. http://dx.doi.org/10.2478/bjdm-2020-0029.

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SummaryBackground/Aim: Gingival recession is defined as apical migration if the gingival margin associated with exposure of the cement - enamel junction. The gingival recessions are major esthetic concern in patients at any age. In cases with esthetic and functional considerations mucogingival surgery is indicated. The advantages of CAF with or without CTG are making this procedure highly recommended in the esthetic zone. The results are predictable about root coverage, widening if the gingival tissues and esthetics. The aim of the recent case report is to demonstrate the succesfull combinatio

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Kataoka, Tetsuro. "TCTAP C-262 Acute Coronary Syndrome Resulted in Longitudinal Stent Elongation During Post-dilatation with Semi-compliant Balloon and Subsequent Thrombus-shift Derived from Culprit Lesion." Journal of the American College of Cardiology 69, no. 16 (2017): S354—S356. http://dx.doi.org/10.1016/j.jacc.2017.03.501.

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Fuerst, Melissa, Carla G. Taylor, Brenda Wright, Leslee Tworek, and Peter Zahradka. "Inhibition of smooth muscle cell proliferation by adiponectin requires proteolytic conversion to its globular form." Journal of Endocrinology 215, no. 1 (2012): 107–17. http://dx.doi.org/10.1530/joe-12-0021.

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Accelerated atherosclerosis is the primary cardiovascular manifestation of diabetes and correlates inversely with levels of circulating adiponectin, an anti-atherosclerotic adipokine that declines in diabetes. We therefore initiated a study to examine the mechanisms by which adiponectin, a hormone released from adipose tissue, influences the proliferation of vascular smooth muscle cells (SMCs). Addition of adiponectin to quiescent porcine coronary artery SMCs increased both protein and DNA synthesis and concurrently activated ERK1/2 and Akt. By contrast, globular adiponectin, a truncated form

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27

Hachida, M., M. Endo, Y. Bonkohara, et al. "Surgical Treatment of Ischaemic Valve Disease." Cardiovascular Surgery 4, no. 2 (1996): 246–49. http://dx.doi.org/10.1177/096721099600400226.

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Mitral valve regurgitation secondary to ischaemic heart disease carries a significant mortality even after open-heart surgery. In this study, 21 patients with mitral regurgitation associated with ischaemic heart disease were evaluated with respect to valvular pathology. Pathological examination of the mitral valve revealed chorda elongation or rupture in seven patients (group 1), papillary muscle dysfunction in 10 (group 2), and papillary muscle rupture in four (group 3). Significant preoperative characteristics in each group were subacute haemodynamic deterioration in group 1, chronic severe

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Liu, Zixiang Leonardo, Christopher Bresette, Cyrus K. Aidun, and David N. Ku. "SIPA in 10 milliseconds: VWF tentacles agglomerate and capture platelets under high shear." Blood Advances 6, no. 8 (2022): 2453–65. http://dx.doi.org/10.1182/bloodadvances.2021005692.

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Abstract Shear-induced platelet aggregation (SIPA) occurs under elevated shear rates (10 000 s−1) found in stenotic coronary and carotid arteries. The pathologically high shear environment can lead to occlusive thrombosis by SIPA from the interaction of nonactivated platelets and von Willebrand factor (VWF) via glycoprotein Ib–A1 binding. This process under high shear rates is difficult to visualize experimentally with concurrent molecular- and cellular-resolutions. To understand this fast bonding, we employ a validated multiscale in silico model incorporating measured molecular kinetics and a

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29

Singh, Shweta. "A Study to Assess the Physio-Culinary Quality of Chia Seeds." International Journal of Health Sciences and Research 11, no. 7 (2021): 119–23. http://dx.doi.org/10.52403/ijhsr.20210717.

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Chia (Salvia hispania l.), constitutes a potential alternative raw material and ingredient in food industry applications. Chia seeds are an abundant source of the n-3 polyunsaturated fatty acid, α-linolenic acid. Alpha-linolenic acid is an essential fatty acid, which, through successive metabolic desaturation and elongation reactions gives rise to dha and epa. EPA and DHA are now widely recognised as having an important role in the prevention of coronary heart disease. Hence, to diversify the use of chia seeds, it was used to develop 4 products, a sweet, a savoury, a drink and a jam in both po

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Barbiero, Silvia, Alberto Aimo, Vincenzo Castiglione, et al. "Healthy hearts at hectic pace: From daily life stress to abnormal cardiomyocyte function and arrhythmias." European Journal of Preventive Cardiology 25, no. 13 (2018): 1419–30. http://dx.doi.org/10.1177/2047487318790614.

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The hectic pace of contemporary life is a major source of acute and chronic stress, which may have a deleterious impact on body health . In the field of cardiovascular disease, acute emotional stress has been associated with coronary spasm and Takotsubo cardiomyopathy, whereas the manifestations of chronic stress have been overlooked, and most underlying pathophysiology remains to be elucidated. Chronic stress affects the neuronal circuitry composed of cortico-limbic structures and the nuclei regulating autonomic function, eliciting a sympatho-vagal imbalance, characterised by adrenergic activ

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31

Akaishi, M., R. M. Schneider, R. J. Mercier, J. B. Agarwal, R. H. Helfant, and W. S. Weintraub. "Analysis of phases of contraction during graded acute myocardial ischemia." American Journal of Physiology-Heart and Circulatory Physiology 250, no. 5 (1986): H778—H785. http://dx.doi.org/10.1152/ajpheart.1986.250.5.h778.

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The quantitative effects of graded ischemia on the phases of contraction in ischemic and nonischemic myocardium were studied in 10 open-chest dogs. During progressive coronary stenosis, an index of the overall severity of ischemia, total myocardial blood flow deficit (TMFD), was measured using microspheres. Segment shortening (% delta L) during the isovolumic and ejection phases of systole in the ischemic and nonischemic zones was obtained with ultrasonic crystals. In the ischemic zone, total systolic and ejection phase % delta L decreased progressively as stenosis increased; isovolumic phase

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32

Ilyas, Kamal Kharrazi, Zainal Safri, Harris Hasan, Zulfikri Mukhtar, Nizam Zikri Akbar, and Andika Sitepu. "Terminal QRS Distortion on Admission ECG as a Predictor for Major Cardiovascular Adverse Events during Hospitalization in Patient with ST Segment Elevation Myocardial Infarction in Haji Adam Malik General Hospital." ACI (Acta Cardiologia Indonesiana) 6, no. 2 (2020): 121–26. http://dx.doi.org/10.22146/jaci.v6i2.628.

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Background: Mortality in patient with acute myocardial infarction has decreased due to evolution in management system in patient with acute coronary syndrome, but mortality rate during hospitalization remains high, especially STEMI. Electrocardiography (ECG) has a role for diagnosing and predict prognosis in acute myocardial infarction. Terminal QRS distortion defined as J point elevation more than 50% of R wave in lead with qR configuration and/or loss of S wave with RS configuration. Changes of terminal QRS segment believed to be caused by electrical conduction elongation in Purkinje fiber o

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Bocharov, A. V., and K. A. Savostyanov. "IS IT WORTH CHANGING THE TACTICAL APPROACHES TO IMPLANTATION OF AN ARTIFICIAL PACEMAKER IN PATIENTS WITH ACUTE MYOCARDIAL INFARCTION IN THE ANTERIOR DESCENDING ARTERY BASIN, DEPENDING ON THE TYPE OF ATRIOVENTRICULAR BLOCK?" Bulletin of Pirogov National Medical & Surgical Center 20, no. 1 (2025): 20–23. https://doi.org/10.25881/20728255_2025_20_1_20.

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Objective: to identify a promising subgroup of patients in the group of patients with acute myocardial infarction and atrioventricular block of II–III degree for implantation of a permanent pacemaker at the earliest possible time.Materials and methods: a retrospective non–randomized study was conducted, which included 124 patients with acute myocardial infarction in the anterior descending artery basin and atrioventricular block of II–III degree. All clinical cases meeting the criteria below were included from a continuous sample of 9687 patients with acute coronary syndrome treated in 2014–20

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Yu, Wen Yan, and Jian Guo Wang. "Finite Element Analysis of Free Expansion of Coronary Stent Based on ANSYS Workbench." Advanced Materials Research 662 (February 2013): 626–31. http://dx.doi.org/10.4028/www.scientific.net/amr.662.626.

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Undertaking the 316L stainless steel as a medical stent material and the coronary stent structure as the research object, ANSYS Workbench12.0 is used to simulate the free expansion process of coronary stent by two expansion methods. Finite element analysis is used to solve such problems as deformation behaviour of the stent, mechanical behaviour as well as nonlinear problems of the stent and balloon interaction during the free expansion process. The simulation results show that the stent and balloon interaction process will appear slip phenomenon, the stent shortening in the axial direction an

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35

Zhmurov, Artem, Andre E. X. Brown, Rustem I. Litvinov, Ruxandra I. Dima, John W. Weisel, and Valeri Barsegov. "Molecular Structural Origins of Clot and Thrombus Mechanical Properties." Blood 118, no. 21 (2011): 2257. http://dx.doi.org/10.1182/blood.v118.21.2257.2257.

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Abstract Abstract 2257 Although the mechanical function of blood clots to stem bleeding is obvious and higher clot stiffness has been associated with premature coronary thrombosis, we are only now beginning to understand the origins of these vital mechanical characteristics. Fibrinogen, the precursor of fibrin, provides building blocks for the fibrin polymer, the scaffold of blood clots and thrombi. The mechanical properties of fibrin molecules are essential for the ability of clots to accomplish hemostasis and are an important determinant of the pathological properties of thrombi, as they con

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Turpin, Chloé, Arwa Fraiwan, and Umut A. Gurkan. "Novel RBC Adhesion and Deformability Assays Reveal Deleterious Effect of Diabetes on RBC Health." Blood 142, Supplement 1 (2023): 1072. http://dx.doi.org/10.1182/blood-2023-182036.

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Diabetes is one of the most important health issues in the world. The number of people living with diabetes has quadrupled since 1980 1. Cardiovascular disease (CVD), mainly coronary and artery disease, remains the most common cause for morbidity and mortality in people living with diabetes 2,3. A better understanding of the effect of diabetes on the deformability and adhesiveness of red blood cells (RBCs) is essential in assessing disease status and evaluating the risk of CVD, as well as in investigating the effectiveness of potential therapies 4-6. In this work we investigate the deformabili

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Frank, Cichocki, Bin Zhang, Martin Felice, Bruce R. Blazar, and Jeffrey S. Miller. "mTORC1 Signaling and Metabolism Are Dynamically Regulated during Human NK Cell Maturation and in Adaptive NK Cell Responses to Viral Infection." Blood 126, no. 23 (2015): 209. http://dx.doi.org/10.1182/blood.v126.23.209.209.

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Abstract Relatively little is known with respect to the metabolic characteristics that define human NK cell maturation and adaptive subsets of NK cells that expand in response to viral infections. The mammalian target of rapamycin (mTOR) signaling pathway integrates many major cellular processes in response to environmental cues to regulate cell growth, proliferation and metabolic states. mTOR is a serine/threonine protein kinase that interacts with several proteins to assemble two distinct complexes named mTOR complex 1 (mTORC1) and 2 (mTORC2). The mTOR-containing complexes have different sen

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Vriz, O., S. Ivanov, M. Szulik, et al. "P1007Aortic root diameters and aortic regurgitation in hypertensive patients and normal subjectsP1008Ultrasonic assessment of backscatter signal intensity of the right ventricle in patients with arterial hypertension as a method of measuring alterations of myocardiumP1009Speckle strain echocardiography for the evaluation of left ventricular dyssynchrony in patients with severe lung diseases and pulmonary hypertensionP1010Impaired left ventricular ejection fraction in a cohort of systemic sclerosis patients: clinical and echocardiographic characteristicsP1011Prognostic role of subclinical left ventricular systolic dysfunction evaluated using strain imaging by speckle-tracking echocardiographyP1012Inferior vena cava diameter is a strong and practical marker of physical activity and fitnessP1013When the heart works for two: morphologic and functional adaptation during pregnancyP1014Extensive use of lung ultrasound in pediatric cardiac surgery: preliminary experienceP1015Asymptomatic delayed right ventricular perforation by cardiac implantable electronic devices lead, echocardiographic featuresP1016Novel echocardiographic prognostic markers for cardiac tamponade in patients with large malignant pericardial effusions. A paradigm shift from flow to tissue imagingP1017Doppler echocardiographic parameters as a marker of cardiac tamponadeP1018Sigmoid septum as a marker of elongation of thoracic aorta caused by progression of atherosclerosisP1019Carotid artery atherosclerosis and stiffness: comparison of different metabolic measuresP1020Feasibility of triple imaging vasodilator stress echo in patients with suspected coronary artery diseaseP1022The use of combined echo and cardio-pulmonary stress for discriminating cardiac problems from de-conditioning in patients with dyspneaP1023Long-term prognosis of a stress echocardiography in patients after successful primary percutaneous intervention and incomplete revascularization of non-culprit lesionsP1024Diastolic exercise stress echo can unmask diastolic dysfunction in type 2 diabetes, a five-year follow-up studyP1025Diabetes mellitus is the major limitation for diagnosis of coronary artery disease assessed by semisupine ergometer stress echocardiographyP1026Longitudinal changes of atherosclerotic features in the aorta on transcatheter aortic valve implantation using transesophageal echocardiographyP1027Severe aortic stenosis: comparison between effective and anatomical aortic?valvular area by two and three dimension transesophageal ecocardiographyP1028Region growing method provides better left ventricular volume and cardaic output measuringP10293 dimensional echocardiographic evaluation of mitral valve geometry in patients with secondary and primary mitral regurgitationP1030The impact of adjustable region of interest on ventricular strain measurements and arrhythmic risk assessment in patients with hypertrophic cardiomyopathyP1031Left ventricular strain at presentation predicts long-term outcome in ALCAPA patientsP1032Global atrial-ventricular strain as a new index of subclinical left heart dysfunction in hypertensive and diabetic patients." European Heart Journal – Cardiovascular Imaging 17, suppl 2 (2016): ii201—ii208. http://dx.doi.org/10.1093/ehjci/jew260.002.

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Matsuba, Tomoyuki, Yoshiya Shigehisa, Itsumi Imagama, and Yutaka Imoto. "A case of arterial switch operation with coronary elongation technique." Surgical Case Reports 2, no. 1 (2016). http://dx.doi.org/10.1186/s40792-016-0134-9.

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Algowhary, Magdy, and Mohammed Aboel-Kassem F. Abdelmegid. "Longitudinal stent elongation or shortening after deployment in the coronary arteries: which is dominant?" Egyptian Heart Journal 73, no. 1 (2021). http://dx.doi.org/10.1186/s43044-021-00170-9.

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Abstract Background Stent manufacturers always record stent shortening data while they do not record stent elongation data. The aim of this study is to identify both stent shortening and elongation occurring after deployment in the coronary arteries and know their percentage. Results The length of coronary stents was measured by intravascular ultrasound (IVUS) by (1) edge-to-edge (E-E) length, measured from the appearance of the first distal strut to the last proximal strut, and (2) area-to-area (A-A) length, measured from the first distal struts seen at more than one IVUS quadrant to the last

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Caimi, Gregorio, Rosalia Lo Presti, Egle Corrado, Maria Montana, and Melania Carlisi. "Red Cell Distribution Width and Elongation Index in a Cohort of Patients With Juvenile Acute Myocardial Infarction." Clinical and Applied Thrombosis/Hemostasis 29 (January 2023). http://dx.doi.org/10.1177/10760296231186148.

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In a cohort of patients with juvenile myocardial infarction, we considered the red cell distribution width (RDW), hematocrit, hemoglobin, and elongation index values at the initial phase and at 3 and 12 months from the acute event. In the initial phase, only the elongation index values turn out reduced if compared with those of the control group, and that only turn out to discriminate the infarcted ST-segment elevation myocardial infarction (STEMI) from non-STEMI. Dividing the patients according to the traditional risk factors and the extent of coronary heart disease, there are no significant

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Tang-Quan, Karis R., Yutao T. Xi, Camila T. Hochman-Mendez, Luiz C. Sampaio, and Doris A. Taylor. "Abstract 16799: Decellularized Cardiac Extracellular Matrix Increases Cardiomyocyte Elongation and Contractility." Circulation 138, Suppl_1 (2018). http://dx.doi.org/10.1161/circ.138.suppl_1.16799.

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Background: Cardiomyocyte elongation has been linked to enhanced myofilament organization, which contributes to overall cell contractility and functionality. While tissue scaffolds have been engineered to induce cell elongation using topographical cues, decellularized cardiac extracellular matrix (dECM) bioscaffolds are known to be bioactive and retain native cues for cell organization and regeneration, including the alignment of stem cells. However, the effects of the native extracellular matrix on cardiomyocyte elongation and contractility are still unknown. Hypothesis: We hypothesized that

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Amstutz, C., J. Behr, S. Krebs, et al. "Design of percutaneous transluminal coronary angioplasty balloon catheters." BioMedical Engineering OnLine 22, no. 1 (2023). http://dx.doi.org/10.1186/s12938-023-01155-2.

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Abstract Background Eight commercially available percutaneous transluminal coronary angioplasty (PTCA), including semi-compliant and non-compliant balloons, have been assessed in detail on their tip, balloon, shaft, RX-Port, and hypotube design. Important performance characteristics such as tip deformation, balloon elongation, and deflation rate have been quantified. Methods Five catheters of each model were evaluated during various tests. The robustness of the tips was evaluated through compression, measuring any occurrence of damage. The longitudinal growth of the balloons was recorded durin

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Hajjaji, S., R. Taktak, H. Hajjami, and A. Boughzella. "The Contribution of Pre-Prosthetic Periodontal Surgery in the Success of Anterior Fixed Prostheses." January 19, 2017. https://doi.org/10.19070/2377-8075-1700080.

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Pre-prosthetic periodontal surgery plays a major role in the aesthetic and functional integration of prosthetic restorations, especially in the anterior area. Indeed, any dento-gingival disharmony of volume or form must be corrected before hand, thus justifying the use of plastic periodontal surgery. Clinical report: A 20-year-old patient consulted our department primarily for an aesthetic reason: the restoration of the fractured 11. The clinical examination revealed the presence of a defective temporary prosthesis on the 11, an aesthetically disturbing composite resin on the 21, an asymmetry

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McChord, J., R. Gollwitzer, A. Seitz, U. Sechtem, R. Bekeredjian, and P. Ong. "Coronary tortuosity in patients with acetylcholine-induced coronary microvascular spasm." European Heart Journal 43, Supplement_2 (2022). http://dx.doi.org/10.1093/eurheartj/ehac544.1130.

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Abstract Background Angina pectoris in the absence of relevant epicardial stenoses (ANOCA) is frequently caused by coronary microvascular spasm. It has been speculated that the morphology of epicardial coronary arteries is associated with microvascular spasm. One hypothesis is that the vasoconstriction of microvessels leads to intraluminal pressure increase in the vascular segments proximal to the spasm, which may shift the balance of vessel forces toward vessel elongation resulting in coronary tortuosity. Purpose We assessed the relationship between epicardial coronary tortuosity and coronary

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Rezvova, Maria A., Evgeny A. Ovcharenko, Kirill Yu Klyshnikov, et al. "Electrospun bioresorbable polymer membranes for coronary artery stents." Frontiers in Bioengineering and Biotechnology 12 (August 21, 2024). http://dx.doi.org/10.3389/fbioe.2024.1440181.

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Percutaneous coronary intervention, a common treatment for atherosclerotic coronary artery lesions, occasionally results in perforations associated with increased mortality rates. Stents coated with a bioresorbable polymer membrane may offer an effective solution for sealing coronary artery perforations. Additionally, such coatings could be effective in mitigating neointimal hyperplasia within the vascular lumen and correcting symptomatic aneurysms. This study examines polymer membranes fabricated by electrospinning of polycaprolactone, polydioxanone, polylactide-co-caprolactone, and polylacti

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Hynek, Chlup, Horny Lukas, Zitny Rudolf, Konvickova Svatava, and Adamek Tomas. "Constitutive Equations for Human Saphenous Vein Coronary Artery Bypass Graft." August 26, 2008. https://doi.org/10.5281/zenodo.1061338.

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Coronary artery bypass grafts (CABG) are widely studied with respect to hemodynamic conditions which play important role in presence of a restenosis. However, papers which concern with constitutive modeling of CABG are lacking in the literature. The purpose of this study is to find a constitutive model for CABG tissue. A sample of the CABG obtained within an autopsy underwent an inflation–extension test. Displacements were recoredered by CCD cameras and subsequently evaluated by digital image correlation. Pressure – radius and axial force – elongation data were used to fit material model. The

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Cavallero, Susana, Hua Shen, Christopher Yi, Ram Kumar Subramanyan, and Henry Sucov. "CXCL12 And Vascular Maturation Of The Coronary System During Heart Development." FASEB Journal 30, S1 (2016). http://dx.doi.org/10.1096/fasebj.30.1_supplement.554.5.

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Elucidating the mechanisms involved in the patterning of coronary blood vessels in the embryo will help to improve therapies for coronary perfusion in the injured heart. In the past few years, there have been significant efforts and advances in the understanding of coronary vessel development. The major endothelial cell sources that provide coronary endothelial progenitors to the heart are the sinus venosus (the vein that delivers the venous return) and the endocardium, although the respective contribution from each source is debated. Angiogenic sprouts from the sinus venosus reach the ventric

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Meza, Daphne, Louie Abejar, David A. Rubenstein, and Wei Yin. "A Shearing-Stretching Device That Can Apply Physiological Fluid Shear Stress and Cyclic Stretch Concurrently to Endothelial Cells." Journal of Biomechanical Engineering 138, no. 3 (2016). http://dx.doi.org/10.1115/1.4032550.

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Endothelial cell (EC) morphology and functions can be highly impacted by the mechanical stresses that the cells experience in vivo. In most areas in the vasculature, ECs are continuously exposed to unsteady blood flow-induced shear stress and vasodilation-contraction-induced tensile stress/strain simultaneously. Investigations on how ECs respond to combined shear stress and tensile strain will help us to better understand how an altered mechanical environment affects EC mechanotransduction, dysfunction, and associated cardiovascular disease development. In the present study, a programmable she

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Di Spigno, Francesco, Andrea Caraffini, Eleonora Canu, Nicola De Santis, and Daniela Aschier. "Myocardial Crypts and Ventricular Fibrillation: Two Case Reports." EMJ Cardiology, September 18, 2024. http://dx.doi.org/10.33590/emjcardiol/xkft3789.

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Background Left ventricular myocardial crypts are defined as invaginations traversing >50% of the myocardial wall, with an incidence of 9.1% in the general population. Several studies have suggested that these morphological findings could be a marker of myocardial disease. The authors present two cases of cardiac arrest (CA) due to ventricular fibrillation (VF) and incidental findings on cardiac magnetic resonance (CMR) of myocardial crypts, discuss the diagnosis, the possible correlation with hypertrophic cardiomyopathy, and hypothesise the significance of this entity. Case Presentation Ca

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