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1

Forsberg, Tim, and Erik Karlsson. "Comparing Two Production Lines Using Simulation." Thesis, Umeå universitet, Institutionen för matematik och matematisk statistik, 2021. http://urn.kb.se/resolve?urn=urn:nbn:se:umu:diva-185237.

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In order to reduce material shortage of doors in production, the current production processes needs adjusting. Currently when the buffer between the Mainline and the Door area is full the production in the unit stops. This is a problem that should not happen.  To circumvent this a new concept was produced and tested with simulation in order to compare the current state with the new concept model. To achieve this, data has been gathered and analyzed to create a model that is a close approximation of reality. Using the same data input, an alternative solution was tested on two variations of the
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2

Walker, Claudio. "Numerical Methods for Two-Phase Flow with Contact Lines." Doctoral thesis, Norges teknisk-naturvitenskapelige universitet, Institutt for energi- og prosessteknikk, 2012. http://urn.kb.se/resolve?urn=urn:nbn:no:ntnu:diva-17462.

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This thesis focuses on numerical methods for two-phase ows, and especially ows with a moving contact line. Moving contact lines occur where the interface between two uids is in contact with a solid wall. At the location where both uids and the wall meet, the common continuum descriptions for uids are not longer valid, since the dynamics around such a contact line are governed by interactions at the molecular level. Therefore the standart numerical continuum models have to be adjusted to handle moving contact lines. In the main part of the thesis a method to manipulate the position and the velo
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3

Holmgren, Hanna. "Modelling of Moving Contact Lines in Two-Phase Flows." Doctoral thesis, Uppsala universitet, Avdelningen för beräkningsvetenskap, 2017. http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-329059.

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Moving contact line problems appear in many natural and industrial processes. A contact line is formed where the interface between two immiscible fluids meets a solid wall. Examples from everyday life include raindrops falling on a window and water bugs resting on water surfaces. In many cases the dynamics of the contact line affects the overall behavior of the system. Industrial applications where the contact line behavior is important include gas and oil recovery in porous media, lubrication, inkjet printing and microfluidics. Computer simulations are fundamental tools to understand and pred
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4

Deon, Jane. "The Lines We Crossed." FIU Digital Commons, 2014. http://digitalcommons.fiu.edu/etd/1150.

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THE LINES WE CROSSED is a historical novel set in Umbria, Italy from 1943-1944. One October morning, Emilia Testadura awakes to find the Nazis have arrived in her village. Major Christoph Strauss presses Emilia into service as housekeeper for the soldiers who now occupy an abandoned palazzo in the village. As the stakes and complications rise in the war throughout winter and spring, so they do for Emilia. Brutal reinforcements arrive and conditions become very dangerous. Emilia realizes she is falling in love with Major Strauss. She learns secrets that change her view of her deceased father an
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5

Bicknell, Gareth Ross. "Biochemical characteristics of apoptosis in two human leukaemic cell lines." Thesis, University of Leicester, 1996. http://hdl.handle.net/2381/34145.

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Apoptosis is a form of cell death in which the cell actively participates. Apoptosis was induced in two human leukaemic cell lines, U937 and HL-60, by incubation with a diverse array of chemical agents. Cell death was assessed by gel electrophoresis, light microscopy and flow cytometry. It was demonstrated that apoptosis involved the formation of large kilobase pair DNA fragments (20-50, 145-245 and 580 kilobase pairs) prior to, or accompanying, internucleosomal cleavage. Degradation of DNA to large kilobase pair sizes also occurred in some forms of necrosis. These fragments were similar, but
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6

Shi, Xuesong. "Synthesis and characterization of two azobenzene-containing ferroelectric liquid crystals and of their corresponding polysiloxanes." Thesis, National Library of Canada = Bibliothèque nationale du Canada, 2001. http://www.collectionscanada.ca/obj/s4/f2/dsk3/ftp05/MQ63365.pdf.

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7

Jordán, Vargas Kathia. "Feed conversion index in two populations and two lines of guinea pigs for meat production." BYU ScholarsArchive, 2005. https://scholarsarchive.byu.edu/etd/5381.

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The guinea pig (Cavia aperea porcellus) is an alternative to improve human nutrition because its meat is of excellent taste and quality. Thus, it is an important nutritional source. The feed conversion index was determined under the basic (forage) and mixed (forage and concentrate) diets during the growth phase. This was done with both sexes located in the Tamborada and MEJOCUY populations, using the AUQUI, and San Luis lines. This was done in order to quantify how many kilograms of feed an animal must eat to gain one kilogram of live weight. The animals were randomly distributed into individu
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8

Schnablegger, Gerald. "The anticancer activity of Cyathula prostrata on two malignant cell lines." Thesis, Nelson Mandela Metropolitan University, 2010. http://hdl.handle.net/10948/1563.

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Plants have always been a source of medicine and are still being used by traditional healers in the rural part of Africa, Asia and India to treat a range of illnesses including cancer. The in vitro anticancer activity of an 80 percent ethanol extract of Cyathula prostrata, an annual branching shrub used by traditional healers in Nigeria to treat cancer was investigated. No previous studies have outlined the possible pathways and mechanisms used by cancer cells when treated with C. prostrata. Dose response analysis was performed to determine the effective cytotoxic concentrations of C. prostrat
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9

Paisley, Derek John. "Characterisation of two mouse mutant lines generated by transgene insertional mutagenesis." Thesis, University of Bath, 2000. https://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.342073.

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10

Grabowsky, Monika Elvira. "Two-dimensional chromatographic characterisation of PS-b-PEO copolymers at the critical conditions of their corresponding homopolymers." Thesis, Stellenbosch : Stellenbosch University, 2011. http://hdl.handle.net/10019.1/17937.

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Thesis (MSc)--Stellenbosch University, 2011.<br>ENGLISH ABSTRACT: Block copolymers are very interesting materials but they are quite complex. During polymer synthesis only a certain amount of control can be enforced. As copolymers are made up of two or more different homopolymer segments, and therefore have different end group possibilities, varying block lengths and block sequences, they have complex structures and are therefore difficult to analyse. Different techniques exist by which polymers can be analysed to determine the aforementioned distributions. In order to achieve a complete
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11

Ruddy, Suzanne. "Mutation of the thymidine kinase gene in two mouse tumour cell lines." Thesis, Queen's University Belfast, 1988. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.336001.

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12

Jones, Felicity Anne. "Growth and voluntary feed intake of two diverse genetic lines of pigs." Thesis, University of Nottingham, 1997. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.284424.

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13

Solymosi, Bence. "A two-way approach to adapt small-scale laboratory experiments and corresponding numerical simulations of offshore seismic surveys." Thesis, Aix-Marseille, 2018. http://www.theses.fr/2018AIXM0630.

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Les méthodes numériques sont largement utilisées en exploration sismique pour simuler la propagation des ondes et pour le post-traitement des données sismiques avant l'interprétation géologique/géophysique. Les algorithmes sont basés sur différentes hypothèses pour réduire le coût de calcul au détriment de la simplification des modèles et/ou des phénomènes physiques. En raison de leur rôle essentiel en exploration géophysique, la précision des simulations numériques présente un fort intérêt, notamment dans le cas de configurations géologiques réalistes. La comparaison directe des résultats num
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14

Payette, Paul J. "Characterization of two Kaposi's sarcoma cell lines and their response to chemotherapeutic agents." Thesis, National Library of Canada = Bibliothèque nationale du Canada, 1998. http://www.collectionscanada.ca/obj/s4/f2/dsk2/tape17/PQDD_0010/MQ28453.pdf.

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15

Healy, Caroline Marie Therese. "Flow cytometric detection of chemically induced tandem repeat mutations in two murine cell lines." Thesis, University of Ottawa (Canada), 2005. http://hdl.handle.net/10393/26920.

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To facilitate detection of genotoxicity from environmental mutagen exposure we generated an in vitro green fluorescence protein (GFP) activation assay that quickly and effectively detects frameshift mutations in tandem repeat sequences (TRS). Two murine cell lines were stably transfected with GFP reporter plasmids in which the GFP constructs contain TRS that shift the GFP coding sequence out of frame. These included several 2-6bp repeat sequences, a control non-repetitive sequence and a human gene sequence with TRS. Transfected cultures were exposed to five model chemicals: hydrogen peroxide (
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16

Towey, Michael Paul. "Characterisation of the genetic defects in two novel MHC class II deficient cell lines." Thesis, King's College London (University of London), 2001. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.270493.

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17

GOMES, VITOR DE CASTRO. "GENETIC SELECTION OF TWO NEW RAT LINES DISPLAYING DIFFERENT LEVELS OF CONDITIONED FREEZING BEHAVIOR." PONTIFÍCIA UNIVERSIDADE CATÓLICA DO RIO DE JANEIRO, 2012. http://www.maxwell.vrac.puc-rio.br/Busca_etds.php?strSecao=resultado&nrSeq=28977@1.

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PONTIFÍCIA UNIVERSIDADE CATÓLICA DO RIO DE JANEIRO<br>CONSELHO NACIONAL DE DESENVOLVIMENTO CIENTÍFICO E TECNOLÓGICO<br>Criação seletiva bidirecional de uma resposta defensiva ou qualquer outra característica fenotípica é uma técnica na qual animais são criados com o objetivo de modificar a frequência dos genes que estão subjacentes a um fenótipo em particular. O acasalamento de animais de uma determinada população com base nos extremos opostos de uma característica observável vai propagar, após diversas gerações, este fenótipo particular em direções opostas, levando-se à criação de duas linhag
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18

Bütler, Timo Martin. "Analysis of phosphotyrosyl protein phosphatases in two human cell lines and in rat tissues." [S.l : s.n.], 1989. http://www.ub.unibe.ch/content/bibliotheken_sammlungen/sondersammlungen/dissen_bestellformular/index_ger.html.

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19

Mazzoni, Luca. "In vitro effects of Alba strawberry cultivars on two murine breast cancer cell lines." Doctoral thesis, Università Politecnica delle Marche, 2015. http://hdl.handle.net/11566/243006.

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L’obiettivo principale degli studi condotti durante il corso di dottorato è stato quello di valutare gli effetti del trattamento con estratti di fragola su 2 modelli murini in vitro di cancro al seno, cercando di verificare se nel meccanismo di azione tramite il quale le fragole sembrano svolgere un’azione antitumorale sia implicato l’AMPK. Nella prima parte degli studi sono state valutate le caratteristiche sensoriali (solidi solubili e acidità totale) e nutrizionali (contenuto totale di fenoli, di flavonoidi, di antociani, di vitamina C e di folati) e la capacità antiossidante di 5 diverse c
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20

Stylin, Nicole. "Mechanism specific effects of two organic pollutants in a single and co-cultured system using two cell lines from Rainbow trout." Thesis, Örebro universitet, Institutionen för naturvetenskap och teknik, 2020. http://urn.kb.se/resolve?urn=urn:nbn:se:oru:diva-86195.

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The present project aims at the investigation of the toxic effects of two organic environmental compounds and to determine whether the interactions of the compounds are different in a single and co-cultured system using two cell lines. The two compounds used for this purpose were PFBS (perfluorobutanesulfonic acid) and BaP (benzo[a]pyrene). For this study, two cell lines from rainbow trout, RTgill-W1 (gills) and RTL-W1 (liver) were used to test the toxic impacts of the selected compounds. The cell lines were cultured before performing the further tests using Neutral red cytotoxicity assay, qPC
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21

Abbott, Heather Elizabeth. "Comparisons of the factors influencing intrinsic radiosensitivity between two isogenic human ovarian carcinoma cell lines." Thesis, National Library of Canada = Bibliothèque nationale du Canada, 2000. http://www.collectionscanada.ca/obj/s4/f2/dsk1/tape2/PQDD_0021/MQ57080.pdf.

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22

Sondergaard, Jeffrey, Kyle Rice, Kira Weaver, Devin Josey, Taylor Gregory, and Christie Monahan. "Comparison Of Two Rat Somatotroph Cell Lines To Examine Tissue-Specific Transcription Of Growth Hormone." Digital Commons @ East Tennessee State University, 2018. https://dc.etsu.edu/asrf/2018/schedule/185.

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Growth Hormone (GH), also known as somatotrophin, is of cardinal importance in the regulation of somatic growth. Decreased GH expression results in short stature, whereas increased levels of GH lead to disorders such as gigantism or acromegaly. Mutations in the transcription factor Pit-1 have been shown to decrease GH, as well as prolactin (PRL; Parks et al., JCEM, 1999). However, understanding the regulation by selective GH transcription regulators, such as Zn16, a protein encoding 16 zinc fingers that binds to the GH promotor DNA (Wojtkiewicz et al., Endocrine, 2002), will require comparison
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23

Chen, Yiwen. "Genome-wide association studies on body weight and component traits in an intercross of two divergently selected chicken lines." Thesis, Uppsala universitet, Institutionen för biologisk grundutbildning, 1997. http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-453443.

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Here we present the genome-wide association study of body weight at 8 weeks of age based onthe advanced intercross pedigree of two chicken lines gone through bi-directional selection.With improved marker density (~3M SNPs) and larger sample size (2667 individuals from F2-F15), 34 loci with suggestive significance are detected, of which 18 loci are novel, and the rest17 loci are consistent with the results of previous quantitative trait locus mapping studies onthis trait with smaller number of genetic markers and fewer individuals. The component traits,referring to traits related to body weight
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24

Ong, Colin Heng Piew. "Biochemical properties of two bovine polynucleotide kinases and a homology-based polymerase chain reaction strategy for identification of the corresponding genes." Thesis, National Library of Canada = Bibliothèque nationale du Canada, 1998. http://www.collectionscanada.ca/obj/s4/f2/dsk1/tape10/PQDD_0004/MQ44237.pdf.

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25

Ong, Colin Heng Piew. "Biochemical properties of two bovine polynucleotide kinases and a homology-based polymerase chain reaction strategy for identification of the corresponding genes." Thesis, McGill University, 1997. http://digitool.Library.McGill.CA:80/R/?func=dbin-jump-full&object_id=20603.

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Four separate polynucleotide kinase activities were observed following Polymin P precipitation of crude extract of calf thymus tissue (Prinos et al., 1995). A single activity designated Polymin P-Precipitable Polynucleotide Kinase (PP-PNK) was detected in the pellet fraction. The other three separable activities, designated SNQl, SNQII and SNQIII, were found in the supernatant fraction after chromatography on a Q-Sepharose column.<br>The PP-PNK activity was purified 4,200 fold after 6 purification steps. The PP-PNK preparation preferentially used ATP as a gamma-phosphoryl donor compared with G
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26

Walker, Paul. "Cloning and characterisation of DNA flanking highly expressed integrated plasmids in two mouse myeloma cell lines." Thesis, University of Leicester, 1999. http://hdl.handle.net/2381/29640.

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Attempts to optimise plasmid vectors for the high level expression of heterologous proteins in the mouse myeloma cell line, J558L, led to the chance discovery of two highly expressing transfectants (C6 and D8). Both these transfectants resulted from plasmids containing a gpt selection marker, a lysozyme reporter gene and the IgH enhancer. Both expressed the lysozyme reporter at around 100 fold higher level than the normally obtained from transfection with the same plasmids, and approximately the same level as the endogenous immunoglobulin genes. This thesis describes the cloning and characteri
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Kelly, Janette Boyd. "Cellular mechanisms in the development of secondary cataract : characterisation of two mammalian lens epithelial cell lines." Thesis, University of the West of Scotland, 2005. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.427715.

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28

Harris, Stephen. "The characterisation of two enhancer trap lines expressed in the embryonic nervous system of Drosophila melanogaster." Thesis, University of Warwick, 1994. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.282431.

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29

Fukuyama, Keita. "Gene expression profiles of liver cancer cell lines reveal two hepatocyte-like and fibroblast-like clusters." Doctoral thesis, Kyoto University, 2021. http://hdl.handle.net/2433/265181.

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30

Kucukkoc, Ibrahim. "Modelling and solving mixed-model parallel two-sided assembly line problems." Thesis, University of Exeter, 2015. http://hdl.handle.net/10871/18917.

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The global competitive environment and the growing demand for personalised products have increased the interest of companies in producing similar product models on the same assembly line. Companies are forced to make significant structural changes to rapidly respond to diversified demands and convert their existing single-model lines into mixed-model lines in order to avoid unnecessary new line construction cost for each new product model. Mixed-model assembly lines play a key role in increasing productivity without compromising quality for manufacturing enterprises. The literature is extensiv
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31

Shukla, Shaleen. "Calculation of Nuclear Level Densities Near the Drip Lines." Ohio University / OhioLINK, 2008. http://rave.ohiolink.edu/etdc/view?acc_num=ohiou1209754262.

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32

Leggio, Loredana. "Functional analysis of two alternative transcripts from porin1 gene of Drosophila melanogaster and involvement of corresponding 5'UTR sequences in the translation control." Doctoral thesis, Università di Catania, 2017. http://hdl.handle.net/10761/3935.

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VDAC (Voltage Dependent Anion-selective channel) is a voltage-dependent anion selective channel, a pore forming protein located in the outer mitochondrial membrane (OMM) of all eukaryotic organisms. This protein allows the passage of nucleotides, ions and small metabolites between cytosol and mitochondria. VDAC has a beta-barrel structure with its N-terminal forming an a-helix inserted into the pore and involved in the gating process. VDAC takes a maximum open state at voltage around 0mV; while at voltages greater than 20mV, for positive and negative values, VDAC switches to a closed state.
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33

Filep, Renee. "In vitro milk protein secretion by explants of Holstein bull mammary tissue from two different genetic lines." Thesis, This resource online, 1990. http://scholar.lib.vt.edu/theses/available/etd-06102009-063451/.

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34

Valtink, Monika, Rita Gruschwitz, Richard H. W. Funk, and Katrin Engelmann. "Two Clonal Cell Lines of Immortalized Human Corneal Endothelial Cells Show either Differentiated or Precursor Cell Characteristics." Saechsische Landesbibliothek- Staats- und Universitaetsbibliothek Dresden, 2014. http://nbn-resolving.de/urn:nbn:de:bsz:14-qucosa-136199.

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Access to primary human corneal endothelial cells (HCEC) is limited and donor-derived differences between cultures exacerbate the issue of data reproducibility, whereas cell lines can provide sufficient numbers of homogenous cells for multiple experiments. An immortalized HCEC population was adapted to serum-free culture medium and repeated cloning was performed. Clonally grown cells were propagated under serum-free conditions and growth curves were recorded. Cells were characterized immunocytochemically for junctional proteins, collagens, Na,K-ATPase and HCEC-specific 9.3.E-antigen. Ultrastru
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35

Valtink, Monika, Rita Gruschwitz, Richard H. W. Funk, and Katrin Engelmann. "Two Clonal Cell Lines of Immortalized Human Corneal Endothelial Cells Show either Differentiated or Precursor Cell Characteristics." Karger, 2008. https://tud.qucosa.de/id/qucosa%3A27701.

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Access to primary human corneal endothelial cells (HCEC) is limited and donor-derived differences between cultures exacerbate the issue of data reproducibility, whereas cell lines can provide sufficient numbers of homogenous cells for multiple experiments. An immortalized HCEC population was adapted to serum-free culture medium and repeated cloning was performed. Clonally grown cells were propagated under serum-free conditions and growth curves were recorded. Cells were characterized immunocytochemically for junctional proteins, collagens, Na,K-ATPase and HCEC-specific 9.3.E-antigen. Ultrastru
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36

Ka, Sojeong. "Gene Expression in the Brains of Two Lines of Chicken Divergently Selected for High and Low Body Weight." Doctoral thesis, Uppsala : Acta Universitatis Upsaliensis : Univ.-bibl.[distributör], 2009. http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-108455.

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37

Mignolet, Alix. "Classification of polyphenolic compounds according to their differential effects on two breast cancer cell lines by FTIR spectroscopy." Doctoral thesis, Universite Libre de Bruxelles, 2017. http://hdl.handle.net/2013/ULB-DIPOT:oai:dipot.ulb.ac.be:2013/246922.

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The development of reliable and cost-saving methods to select pre-clinically new potential drugs with unknown and original mechanisms of action for cancer therapy has become crucial. Previous investigations demonstrated that infrared spectra of cancer cells exposed to well-known anticancer drugs used in the clinics provide a global fingerprint of all the metabolic modifications induced. Nowadays several natural products have been recognized for their medicinal values. Polyphenolic compounds constitute one of the largest groups of plant metabolites and many studies have demonstrated their antic
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38

Cui, Yuhai. "A structural and transcriptional comparative analysis of the S locus regions in two self-incompatible Brassica napus lines." Thesis, National Library of Canada = Bibliothèque nationale du Canada, 1999. http://www.collectionscanada.ca/obj/s4/f2/dsk2/ftp02/NQ43253.pdf.

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39

Gregory, Taylor, Devin Josey, Alexa Bancroft, et al. "RNA-Seq to analyze two related rat Growth Hormone-producing somatotroph cell lines for tissue-specific transcript expression." Digital Commons @ East Tennessee State University, 2019. https://dc.etsu.edu/asrf/2019/schedule/154.

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Growth Hormone (GH), also known as somatotropin, is a protein hormone secreted from the anterior pituitary gland. GH action results in longitudinal bone growth in children and adolescents and continues later to control a variety of metabolic reactions in adults. DNA polymorphisms leading to a decrease in GH expression result in persons of short stature, whereas those leading to overexpression of GH produce either acromegaly or gigantism. In order to diagnose and treat patients with altered GH production, understanding the control of GH expression is thus clinically relevant. In order to un
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40

Gilbert, Elizabeth R. "Dietary and Developmental Regulation of Nutrient Transporter Gene Expression in the Small Intestine of Two Lines of Broilers." Diss., Virginia Tech, 2008. http://hdl.handle.net/10919/28795.

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To better understand the digestive and absorptive capacities of the chick intestine so that we may feed diets that better meet the nutritional needs of the chick, it is important to understand how expression of nutrient transporter genes changes in response to various factors. A series of feeding trials were conducted to evaluate the dietary and developmental regulation of nutrient transporter mRNA abundance in the small intestine of two lines of broilers selected on corn-based (Line A) or wheat-based (Line B) diets. Abundance of mRNA was quantified in all experiments using real time PCR and t
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Smith, Kelsey. "Identifying Frogeye Leaf Spot Resistance in Two Elite Soybean Populations and Analysis of Agronomic Traits in Resistant Lines." OpenSIUC, 2021. https://opensiuc.lib.siu.edu/theses/2843.

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Soybeans (Glycine max L.) are an important crop globally for its food, feed, and oilpurposes. It is impacted by many diseases, including Cercospora sojina, the causal agent of Frogeye Leaf Spot (FLS). Chemical and cultural controls to this fungal pathogen are insufficient, so genetic resistance must be acquired for adequate control. To this end, two recombinant inbred populations were screened in a greenhouse setting for their relative resistance to FLS, and their genomes were analyzed for contributing quantitative trait loci (QTL). In the Essex ́ Forrest population, one QTL was discovered on
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42

Papageorgiou, Vassilios A. "Static two-dimensional calculation of the capacitance and impedance of open microstrip-like structures using variational methods." Thesis, This resource online, 1993. http://scholar.lib.vt.edu/theses/available/etd-08182009-040513/.

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43

Diédhiou, Calliste Jérémie. "Mechanisms of salt tolerance sodium, chloride and potassium homeostasis in two rice lines with different tolerance to salinity stress /." [S.l.] : [s.n.], 2006. http://deposit.ddb.de/cgi-bin/dokserv?idn=979864097.

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44

Tognatta, Reshmi [Verfasser]. "CNP-expressing progenitors display strikingly differential oligodendroglial or multipotent fates, as assessed by two Cre reporter lines / Reshmi Tognatta." Bonn : Universitäts- und Landesbibliothek Bonn, 2012. http://d-nb.info/1044867574/34.

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45

Yeoh, Sue-Ching. "Gene Expression Profiling Of Two Oral Squamous Cell Carcinoma Cell Lines Compared With Normal Oral Epithelium, Using Cdna Microarray." Thesis, Faculty of Dentistry, 2006. http://hdl.handle.net/2123/5040.

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46

Mahaye, Ntombikayise. "A central enrichment-based comparison of two alternative methods of generating transcription factor binding motifs from protein binding microarray data." Thesis, Rhodes University, 2013. http://hdl.handle.net/10962/d1003049.

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Characterising transcription factor binding sites (TFBS) is an important problem in bioinformatics, since predicting binding sites has many applications such as predicting gene regulation. ChIP-seq is a powerful in vivo method for generating genome-wide putative binding regions for transcription factors (TFs). CentriMo is an algorithm that measures central enrichment of a motif and has previously been used as motif enrichment analysis (MEA) tool. CentriMo uses the fact that ChIP-seq peak calling methods are likely to be biased towards the centre of the putative binding region, at least in case
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47

Alvi, Mohammed M. "Lysosomal Targeting of a Gelatin-Doxorubicin Conjugate and Its Evaluation for Cell Damage in Two Model Breast Cancer Cell Lines." Thesis, University of the Sciences in Philadelphia, 2021. http://pqdtopen.proquest.com/#viewpdf?dispub=28154563.

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Doxorubicin (DOX) is one of the most potent anthracycline antibiotics used for treatment of multiple tumor types including breast cancer treatment. However, its efficacy is limited by fatal toxicities associated with DOX therapy causing damage to healthy tissues and organs. In this project, a high molecular weight gelatin-doxorubicin (GDOX) conjugate was synthesized and purified. Gelatin was linked to DOX in this conjugation via glygly spacer and an acid labile hydrazone bond. GDOX was characterized for molecular weight distribution of gelatin by size exclusion chromatography. Drug load on the
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48

Sumners, Lindsay Hart. "Immunological Response to Clostridium perfringens in Two Genetically Divergent Lines of Chickens as Influenced by Major Histocompatibility Complex (MHC) Genotype." Thesis, Virginia Tech, 2011. http://hdl.handle.net/10919/43370.

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Chickens genetically selected for low (LA) or high (HA) antibody response to sheep red blood cells (SRBC) displayed a correlated change in major histocompatibility complex (MHC), so that LA chickens were 96% B13 and HA chickens were 96% B21. During a clinical outbreak of necrotic enteritis, B21B21 genotypes experienced significantly less mortality (6% vs. 13 %) compared to B13B13 genotypes. A study was carried out to assess immunological differences between LA and HA lines during exposure to Clostridium perfringens. In Experiment 1, chickens were orally gavaged with a low (10^7 CFU/mL) or high
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49

Kalghatgi, Roshan Satish. "Reconstruction techniques for fixed 3-D lines and fixed 3-D points using the relative pose of one or two cameras." Thesis, Georgia Institute of Technology, 2012. http://hdl.handle.net/1853/43590.

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In general, stereovision can be defined as a two part problem. The first is the correspondence problem. This involves determining the image point in each image of a set of images that correspond to the same physical point P. We will call this set of image points, N. The second problem is the reconstruction problem. Once a set of image points, N, that correspond to point P has been determined, N is then used to extract three dimensional information about point P. This master's thesis presents three novel solutions to the reconstruction problem. Two of the techniques presented are for detectin
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50

Heimann, Felix [Verfasser], and Peter [Akademischer Betreuer] Bastian. "An Unfitted Higher-Order Discontinuous Galerkin Method for Incompressible Two-Phase Flow with Moving Contact Lines / Felix Heimann ; Betreuer: Peter Bastian." Heidelberg : Universitätsbibliothek Heidelberg, 2013. http://d-nb.info/117738101X/34.

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