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Journal articles on the topic 'Corticosteroid overuse Prescription Compliance'

Author: Grafiati

Published: 2 June 2025

Last updated: 31 July 2025

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1

Prajval, Tidke* Dr. Asawali Pawar Swati Deshmukh. "Topical Steroid: A Study on Awareness, Misuse and Perceptions Among Patients and Pharmacists." International Journal of Pharmaceutical Sciences 3, no. 5 (2025): 3312–24. https://doi.org/10.5281/zenodo.15469268.

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Topical corticosteroids (TCs) are commonly prescribed for inflammatory skin conditions such as eczema, psoriasis, and dermatitis due to their anti-inflammatory and immunosuppressive properties. Despite their effectiveness, prolonged or improper use can lead to adverse effects like skin thinning, steroid-induced dermatitis, and systemic complications such as adrenal suppression. A study was conducted to assess awareness, misuse, and perceptions of TCs among 114 participants, including patients, pharmacists, and doctors. The results revealed significant gaps in knowledge and usage patterns. Whil

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Cárdenas Contreras, Remedios, Alicia Habernau Mena, Elisa Haroun Díaz, et al. "Corticosteroid prescription in children with respiratory symptoms." Allergologia et Immunopathologia 52, no. 3 (2025): 115–21. https://doi.org/10.15586/aei.v53i3.1277.

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Asthma is one of the most common childhood diseases. Most children respond to low doses of corticosteroids and/or anti-leukotrienes. However, a small percentage remain symptomatic. They require high doses of inhaled corticosteroids (ICS) and anti-leukotrienes, sometimes with long-acting bronchodilators (LABA) and occasionally systemic corticosteroids (SC). However, we frequently observe that the only treatment they receive for exacerbations is short-acting beta-agonists (SABA) and oral corticosteroids (OC) without adding ICS as a maintenance treatment to prevent new episodes. This leads to fre

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Bibi, Gulzaib, Huzaima Shahzadi, Ayesha Nadeem, et al. "Patterns of Corticosteroid Prescriptions among Patients at Community Pharmacies in Lahore, Pakistan." Journal of Pharmaceutical Research International 36, no. 10 (2024): 55–68. http://dx.doi.org/10.9734/jpri/2024/v36i107589.

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Background: Corticosteroids are a class of steroid hormones produced by the adrenal gland and are used to treat many diseases, including autoimmune diseases and inflammatory diseases. Besides their role in many diseases, long-term use, misuse, and overuse cause side effects including hypertension, diabetes mellitus, and osteoporosis. Objective: The aim of current study is to evaluate the prescription pattern of corticosteroids in different community pharmacies, among patients, in Lahore. Methods: The cross-sectional stratified convenient study performed using a validated questionnaire to analy

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Christo, Paul J. "Urine Drug Testing In Chronic Pain." Pain Physician 3;14, no. 2;3 (2011): 123–43. http://dx.doi.org/10.36076/ppj.2011/14/123.

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Therapeutic use, overuse, abuse, and diversion of controlled substances in managing chronic non-cancer pain continue to be an issue for physicians and patients. The challenge is to eliminate or significantly curtail abuse of controlled prescription drugs while still assuring the proper treatment of those patients. Some physicians are apprehensive regarding the use of chronic opioid therapy in chronic non-cancer pain due to a perceived lack of proven evidence, the misuse of opioids, tolerance, dependence, and hyperalgesia. However, others have criticized the underuse of opioids, resulting in th

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Rose, Samman, Sundus Sardar, Sreethish Sasi, Dabia Hamad S. H. Al Mohanadi, Ahmed Ali A. A. Al-Mohammed, and Muhammad Zahid. "Time for change in practice of in-patient oxygen therapy: a period-limited, multidimensional approach to improve oxygen prescription compliance: quality improvement project at Hamad General Hospital, Qatar." BMJ Open Quality 10, no. 4 (2021): e001574. http://dx.doi.org/10.1136/bmjoq-2021-001574.

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Prescription of oxygen therapy has traditionally poor compliance across the globe and mostly given to patients on verbal orders leading to under or overuse. The British Thoracic Society (BTS) guidelines (2017) recommend that oxygen therapy must be prescribed. Our study aimed to assess the prescription practice of oxygen therapy for patients admitted to acute medical assessment unit and general medical wards at Hamad General Hospital, Qatar and to achieve 80% compliance of valid oxygen therapy prescription implementing the quality improvement model against the BTS guidelines.The prescription pr

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Thein, Onn Shaun, Cathleen Man Ting Chan, Eleanor McCance, Maria Mullins, and Davinder Dosanjh. "Oxygen prescription: improving compliance using methods from BMJ Open Quality journal." BMJ Open Quality 7, no. 2 (2018): e000288. http://dx.doi.org/10.1136/bmjoq-2017-000288.

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Oxygen is an important drug frequently used in the management of acutely unwell hospital patients. However, oxygen overuse can have fatal side effects particularly for those patients at risk of iatrogenic hypercapnia. British Thoracic Society Guidelines state that oxygen must be prescribed for all patients, with target saturations stipulated on the prescription for patient safety. A quality improvement project was undertaken with the aim to improve the oxygen prescription rate across the respiratory ward at a district general hospital, over a period of 3 months. Quality improvement methods wer

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Elhassan, Moawia M. A., Arwa A. S. A. Ali, and Mohamed O. M. Elmustafa. "Adherence to guidelines on prophylaxis of chemotherapy-induced nausea and vomiting in the National Cancer Institute, Sudan." South African Journal of Oncology 1 (February 28, 2017): 5. http://dx.doi.org/10.4102/sajo.v1i0.9.

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<strong>Objective</strong>: To evaluate the adherence to American Society of Clinical Oncology (ASCO) guidelines for antiemetic prophylaxis of chemotherapy-induced nausea and vomiting and assess the outcomes of the prescribed antiemetic drugs.<br /> <strong>Methods</strong>: This prospective, observational study enrolled chemotherapy-naive cancer patients who were admitted to the National Cancer Institute between May and July 2015 for intravenous chemotherapy. Patient’s demographic data, chemotherapy protocols and types of antiemetic drugs were collected by review

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Hagedoorn, Nienke N., Josephine H. L. Wagenaar, Daan Nieboer, et al. "Impact of a clinical decision rule on antibiotic prescription for children with suspected lower respiratory tract infections presenting to European emergency departments: a simulation study based on routine data." Journal of Antimicrobial Chemotherapy 76, no. 5 (2021): 1349–57. http://dx.doi.org/10.1093/jac/dkab023.

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Abstract Background Discriminating viral from bacterial lower respiratory tract infections (LRTIs) in children is challenging thus commonly resulting in antibiotic overuse. The Feverkidstool, a validated clinical decision rule including clinical symptoms and C-reactive protein, safely reduced antibiotic use in children at low/intermediate risk for bacterial LRTIs in a multicentre trial at emergency departments (EDs) in the Netherlands. Objectives Using routine data from an observational study, we simulated the impact of the Feverkidstool on antibiotic prescriptions compared with observed antib

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Murtala, Hassan Adam, Sadiya Abdulqadir Abdulmajid, Aisha Adam Abdullahi, et al. "Prescription of Anti-Malarial Drugs to Patients with Negative Malarial Rapid Diagnostic Test (mRDT) Result by Health Care Workers in Kano, Nigeria." Dutse Journal of Pure and Applied Sciences 10, no. 2b (2024): 68–77. http://dx.doi.org/10.4314/dujopas.v10i2b.7.

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The World Health Organization and the National Malaria Treatment Guideline recommend parasitebased malaria diagnosis by light microscopy or Rapid Diagnostic Tests (RDTs). Positive result is the only indication for anti-malarial treatment whereas negative cases should be reassessed for other common causes of fever. However, contrary to this and for reasons not to be cleared, health workers (HWs) still prescribe antimalarial to patients with negative malarial rapid diagnostic test (mRDT) results of antimalarial drug resistance. To explore the possible reasons for this practice, we assessed compl

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Ulahannan, Thomas J., and Linda A. Lavelle. "Is systematic osteoporosis prevention and detection possible in a district hospital?" Journal of Clinical Effectiveness 2, no. 2 (1997): 43–46. http://dx.doi.org/10.1108/eb020863.

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Osteoporosis demands systematic management for optimum use of resources. Guidelines from the Primary Care Rheumatology Society (PCRS) aim to improve its diagnosis and treatment. We identified all admissions over three months to a district general hospital of patients with fracture of femur, vertebra, or distal forearm and of women who underwent oophorectomy or hysterectomy. We audited their care using the criteria that the diagnosis and risk of osteoporosis should be recorded; that management should follow PCRS guidelines; and that this information should be communicated to general practitione

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Chauhan, Puneet, Junaid Tantray, and Dr Sourabh Kosey. "A Critical Review on Prescribing Pattern Monitoring of Neurological Disorders in a Tertiary Care Teaching Hospital." International Journal of Science and Healthcare Research 7, no. 4 (2022): 35–43. http://dx.doi.org/10.52403/ijshr.20221006.

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Neurological diseases have a significant impact on global health. According to the most recent estimates, the neurological disorders included in the Global Burden of Disease (GBD) Study—and Alzheimer's other dementias, Parkinson's disease, multiple sclerosis, epilepsy, and headache disorders (migraine, tension-type headache [TTH], and medication-overuse headache [MOH]—represent 3% of the global disease burden. [1] Prescription pattern monitoring studies (PPMS) are drug use studies that concentrate on prescription prescribing, dispensing, and administration. They advocate for the proper use of

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Diwan, Vishal, Yogesh D. Sabde, Emma Byström, and Ayesha De Costa. "Treatment of pediatric diarrhea: a simulated client study at private pharmacies of Ujjain, Madhya Pradesh, India." Journal of Infection in Developing Countries 9, no. 05 (2015): 505–11. http://dx.doi.org/10.3855/jidc.5694.

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Introduction: In low- and middle-income countries such as India, private pharmacies play an important role in medical treatments, offering advice for common illnesses such as diarrhea and respiratory tract infections. There is a need to explore the details of the dispensing practices at the private pharmacies in low- and middle-income countries. Methodology: The present study used simulated client methodology to assess the actual dispensing practices for patients with pediatric diarrhea at private pharmacies in an urban setting of an Indian province. Results: This study identified 164 private

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Eibs, Tonka, Alena Koscalova, Mohit Nair, et al. "Qualitative study of antibiotic prescription patterns and associated drivers in Sudan, Guinea-Bissau, Central African Republic and Democratic Republic of Congo." BMJ Open 10, no. 9 (2020): e036530. http://dx.doi.org/10.1136/bmjopen-2019-036530.

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ObjectivesThe objective of this study was to address the knowledge gap regarding antibiotic use in Medecins Sans Frontiéres (MSF) projects located in Africa by exploring antibiotic prescription and consumption habits and their drivers at different healthcare levels.DesignThis study used an exploratory study design through thematic analysis of semistructured, in-depth interviews, focus group discussions (FGDs) and field observations in order to understand the main drivers influencing current antibiotics prescription habits and consumption habits of patients in different geographical settings.Se

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Katz, Pablo M., and Valeria Pegoraro. "The use of corticosteroids in patients with chronic obstructive pulmonary disease: epidemiological and economic aspects." Farmeconomia. Health economics and therapeutic pathways 10, no. 4 (2009): 139–48. http://dx.doi.org/10.7175/fe.v10i4.188.

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Objective: this study aimed at assessing the level of compliance to GOLD guidelines regarding the use of ICS containing drugs for the treatment of patients with COPD in the GPs setting in Italy and at evaluating the economic consequences that the use of corticosteroids may have, specifically in mild and moderate COPD patients where it is inappropriate. Methods: the retrospective GPs database study has analyzed patients with at least one diagnosis of COPD during the period January 2005 – December 2008 who had a report of VEMS and at least one prescription of a drug from ATC R03 class within two

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Grakh, Kushal, Dinesh Mittal, Tarun Kumar, et al. "Attitude, Opinions, and Working Preferences Survey among Pet Practitioners Relating to Antimicrobials in India." Antibiotics 11, no. 10 (2022): 1289. http://dx.doi.org/10.3390/antibiotics11101289.

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The indiscriminate usage and overuse of antimicrobials in pets or companion animals are underlying causes of antimicrobial resistance (AMR). Despite the multi-faceted global challenge presented by antimicrobial resistance, very few studies have appraised pet practitioners’ factors, such as written policy on antimicrobials, dose rate prescribed, use of critically important antimicrobials, and antimicrobial prescription in clean surgical procedures, which can contribute to AMR. In the present study, an online cross-sectional survey among randomly selected pet practitioners (n = 104) of various I

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Hitesh, Kangra, Ahuja Siddharth, Kumar Naveen, et al. "Study of Corticosteroids Utilization in the Department of General Medicine and Dermatology at a Tertiary Care Teaching Hospital, Nuh, Haryana." International Journal of Toxicological and Pharmacological Research 14, no. 11 (2024): 102–12. https://doi.org/10.5281/zenodo.14587965.

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<strong>Background: </strong>Corticosteroids are used consistently in healthcare for the management of several immunological and inflammatory diseases. To keep better regulation over the quality of drug utilization or prescribing in terms of appropriate/rational use of corticosteroids in any healthcare setting, it is necessary to estimate and evaluate its pattern of drug utilization by periodically conducting the DUE (drug utilization evaluation) studies. <strong>Aim and Objectives: </strong>Estimation and evaluation of the pattern of corticosteroid utilization to promote their

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ADDA, Danjuma Kamlen, Obed Tiwah JOHN, Prof Barnabas Toge, et al. "Antimicrobial Prescription Habits among Community Pharmacists and Patent and Proprietary Medicine Vendors in Nigeria: A Rational Use of Drugs Survey." International Journal of Research and Innovation in Applied Science VIII, no. XI (2023): 95–112. http://dx.doi.org/10.51584/ijrias.2023.81109.

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Introduction Antimicrobial Resistance (AMR) poses a global health threat, exacerbated by the misuse and overuse of antimicrobials. The need to investigate knowledge, attitudes, and practices among Community Pharmacists (CPs) and Patent and Proprietary Medicine Vendors (PPMVs) in Nigeria cannot be overemphasized. This study addresses the gaps in understanding antimicrobial dispensing practices among CPs and PPMVs in Nigeria. Materials/Methods A Community-based Antimicrobial Stewardship survey was conducted across five Nigerian states. A total of 384 PPMVs and 135 CPs were interviewed using a we

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Saleh, Hager Ali, Michael A. Borg, Cecilia Stålsby Lundborg, and Erika A. Saliba-Gustafsson. "General Practitioners’, Pharmacists’ and Parents’ Views on Antibiotic Use and Resistance in Malta: An Exploratory Qualitative Study." Antibiotics 11, no. 5 (2022): 661. http://dx.doi.org/10.3390/antibiotics11050661.

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Background: Antibiotic resistance (ABR) remains a global health threat that requires urgent action. Antibiotic use is a key driver of ABR and is particularly problematic in the outpatient setting. General practitioners (GPs), the public, and pharmacists therefore play an important role in safeguarding antibiotics. In this study, we aimed to gain a better understanding of the antibiotic prescribing-use-dispensation dynamic in Malta from the perspective of GPs, pharmacists, and parents; Methods: we conducted 8 focus groups with 8 GPs, 24 pharmacists, and 18 parents between 2014 and 2016. Data we

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Anthonisen, NR, K. Woodlrage, and J. Manfreda. "Use of Spirometry and Respiratory Drugs in Manitobans Over 35 Years of Age with Obstructive Lung Diseases." Canadian Respiratory Journal 12, no. 2 (2005): 69–74. http://dx.doi.org/10.1155/2005/974678.

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BACKGROUND: Previous data indicated that spirometry was underused in people with obstructive disease, especially those with chronic obstructive pulmonary disease (COPD).OBJECTIVE: To examine the use of respiratory drugs in patients with COPD and asthma, and to relate drug use to spirometry.METHODS: Manitoba Health maintains a database of physician services remunerated by fees that includes spirometry. The database contains the diagnosis and patient identifiers, as well as sex, date of birth and residential postal code. Similar identifiers are used in the provincial pharmacare program that reco

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Talaat, Maha, Sara Tolba, Enjy Abdou, Mohamed Sarhan, Mohamed Gomaa, and Yvan J.-F. Hutin. "Over-Prescription and Overuse of Antimicrobials in the Eastern Mediterranean Region: The Urgent Need for Antimicrobial Stewardship Programs with Access, Watch, and Reserve Adoption." Antibiotics 11, no. 12 (2022): 1773. http://dx.doi.org/10.3390/antibiotics11121773.

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Excessive antimicrobial use contributes to the development of antimicrobial resistance. In the Eastern Mediterranean region (EMR), there is dearth of information on the prevalence of antimicrobial use in patients hospitalized in acute healthcare settings, clinical indications, types of antimicrobials prescribed, and quality indicators for prescriptions. Between September and December 2019, seven countries in the EMR conducted a standardized point prevalence survey. All patients present in the hospital wards at 8 a.m. on the day of the survey constituted the sample population. We collected data

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Tebaa, H., H. Arabi, A. Mougui, and I. El Bouchti. "AB1711 EVALUATION OF KNOWLEDGE AND OBSERVANCE OF PRESCRIBED TREATMENTS FOR HOSPITALIZED PATIENTS IN A RHEUMATOLOGY DEPARTMENT." Annals of the Rheumatic Diseases 82, Suppl 1 (2023): 2092.2–2093. http://dx.doi.org/10.1136/annrheumdis-2023-eular.6010.

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BackgroundPatients’ knowledge of their treatment is part of therapeutic education programs.ObjectivesWe studied this knowledge in patients hospitalized in a rheumatology department and the impact on therapeutic compliance.MethodsWe conducted a monocentric prospective observational study. 104 Patients of the rheumatology department who were major and autonomous with their treatments had to answer a questionnaire in 2 parts: the first part concerned the global knowledge of their medication formalized in 4 criteria (name, indication, dosage, specificity), a global knowledge score on 4 points was

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Jenkins-Jones, Sara, Lotta Parviainen, John Porter, et al. "Poor compliance and increased mortality, depression and healthcare costs in patients with congenital adrenal hyperplasia." European Journal of Endocrinology 178, no. 4 (2018): 309–20. http://dx.doi.org/10.1530/eje-17-0895.

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Objectives To evaluate the risks of depression and all-cause mortality, healthcare utilisation costs and treatment adherence in congenital adrenal hyperplasia (CAH) in the United Kingdom. Design and methods A retrospective, matched-cohort study using UK primary-care data from the Clinical Practice Research Datalink linked to hospital and death certification data. Patients diagnosed with CAH and having ≥1 corticosteroid prescription were matched 1:10 to reference subjects. Risk of death and lifetime prevalence of depression were compared using Cox regression models. Direct financial costs were

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Jordaan, M., J. du Plessis, D. Rakumakoe, and L. Mostert. "Orthopaedic surgical antibiotic prophylaxis administration compliance with prescribing guidelines in a private hospital in North West province, South Africa." SA Orthopaedic Journal 22, no. 2 (2023): 86–90. http://dx.doi.org/10.17159/2309-8309/2023/v22n2a4.

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BACKGROUND: The correct use of surgical antibiotic prophylaxis (SAP), as stipulated in evidence-based guidelines, is essential to prevent surgical site infections (SSIs) following orthopaedic procedures and consequently the impact thereof on the patient and healthcare system. Orthopaedic SSIs are associated with devastating complications with a great burden of disease on patients. METHODS: A cross-sectional study was performed in a 186-bed private hospital, located in North West province, South Africa. Retrospective data of adult patients who underwent orthopaedic surgery from 1 January 2020 t

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Ayub, Fiza, Tahir Mehmood Khan, Muhammad Usman Amin, et al. "Comparison of General Use of Antibiotics between Medical and Nonmedical University Students of Lahore." BioMed Research International 2023 (April 24, 2023): 1–5. http://dx.doi.org/10.1155/2023/8534944.

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Objective. To compare the knowledge of antibiotic resistance between medical and nonmedical university students of Lahore. Methodology. An observational cross-sectional survey-based study was conducted among students of Lahore, Pakistan, from November 12, 2021, to December 13, 2021. The convenience sampling method was used to select students. Descriptive analysis and chi-square test were performed using Statistical Package for Social Sciences version 25.0. Results. 52.9% medical and 42.25% nonmedical students knew about antibiotics. 24.1% medical and 18.3% nonmedical students do not take antib

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Morin, Frances, and Neil Desai. "47 Clinical Approach to Febrile Urinary Tract Infections in Young Children Presenting to the Paediatric Emergency Department: A Retrospective Study of National Guideline Compliance." Paediatrics & Child Health 28, Supplement_1 (2023): e21-e21. http://dx.doi.org/10.1093/pch/pxad055.047.

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Abstract Background Antimicrobial resistance is one of the greatest threats to global health. Antibiotic overuse drives antimicrobial resistance. Suspected urinary tract infection (UTI) is a key area of over-prescribing in many clinical settings but has not been investigated in the paediatric emergency department (ED). Objectives Here, we explore compliance with national UTI management guidelines in a paediatric emergency department setting and characterize patient and provider factors associated with guideline non-compliance. Design/Methods We performed retrospective chart review of patients

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Kartic, Prasad Singh. "An Observational Assessment of Drug Utilization in Cardiovascular Disease at a Tertiary Care Facility." International Journal of Toxicological and Pharmacological Research 13, no. 10 (2023): 316–19. https://doi.org/10.5281/zenodo.11075883.

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<strong>Aim: </strong>The aim of the present study was to evaluate the drug utilization in cardiovascular disease at a teaching and referral hospital in Bihar region. <strong>Methods: </strong>The present study was conducted for the period of 6 months. A total of 200 prescriptions of the patients attending hospital OPD of the selected hospitals over a period of 6 months were randomly identified and included in this study. <strong>Results: </strong>Based on the results obtained it is found that male patients 61.5% had high frequency of cardiovascular incidences when com

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Park, J. J., H. Koo, Y. Park, et al. "DOP18 Impact of adherence to anti-tumour necrosis factor therapy on clinical outcomes in Crohn’s disease: A nationwide population-based study." Journal of Crohn's and Colitis 14, Supplement_1 (2020): S058. http://dx.doi.org/10.1093/ecco-jcc/jjz203.057.

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Abstract Background The impact of compliance with anti-tumour necrosis factor (TNF) on the clinical outcomes of Crohn’s disease (CD) is not well unknown. We performed a nationwide population-based study to investigate the impact of adherence to anti-TNF therapy on clinical outcomes in CD patients. Methods Using the National Health Insurance claims data, we collected data on newly diagnosed patients with CD between 2004 and 2015. Given that infliximab was listed in the National Health Insurance Service in 2006 and adalimumab in 2010, data only after the listing date were extracted. A total of 2

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Shireman, Theresa I., Pamela C. Heaton, Wendy E. Gay, Robert J. Cluxton, and Charles J. Moomaw. "Relationship between Asthma Drug Therapy Patterns and Healthcare Utilization." Annals of Pharmacotherapy 36, no. 4 (2002): 557–64. http://dx.doi.org/10.1345/aph.1a067.

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BACKGROUND AND OBJECTIVE: Asthma drug therapy problems contribute significantly to preventable hospitalizations and increased healthcare use in asthmatics. Since asthma patients often require >1 medication for control of symptoms, concurrent asthma drug therapies may be important in predicting excessive healthcare utilization. The purpose of this study was to link inappropriate asthma drug therapy patterns and selected patient demographics to healthcare utilization. METHODS: This study was a retrospective, cross-sectional analysis of Ohio Medicaid medical, institutional, and prescription cl

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Asogwa, I. C., I. Chiojioke-Nwauche, E. I. Otuku, and O. I. Ekwunife. "A Review of the use of Rational and Quality Antibiotics in a Nigerian Tertiary Institution." American Journal of Health, Medicine and Nursing Practice 7, no. 12 (2022): 12–21. http://dx.doi.org/10.47672/ajhmn.1282.

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Purpose: The study reviewed the use of rational and quality antibiotics at the Federal Medical Centre, Yenagoa, Bayelsa State. Three objectives and three research questions were drafted for the study, respectively. Methodology: The study used a retrospective descriptive survey that lasted four months. The study relied on secondary data, which was gathered from the folders of 583 patients. From January 1, 2019 to April 30, 2019, all patients with complete information admitted to medical, surgical, and paediatric wards, as well as obstetrics and gynaecology wards, had their folders reviewe

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Worth, Heinrich, Carl-Peter Criée, Claus F. Vogelmeier, et al. "Prevalence of overuse of short-acting beta-2 agonists (SABA) and associated factors among patients with asthma in Germany." Respiratory Research 22, no. 1 (2021). http://dx.doi.org/10.1186/s12931-021-01701-3.

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Abstract Background Overuse of short-acting beta-2 agonists (SABA), which do not treat the underlying inflammation of asthma, is linked to poor clinical outcomes such as increased exacerbation risk. This study, as part of the SABINA program, estimated the prevalence of SABA overuse and associated variables in outpatients in Germany. Methods This retrospective study used anonymized electronic healthcare data from the Disease Analyzer database (IQVIA). A total of 15,640 patients aged ≥ 12 years with asthma who received ≥ 1 SABA prescription(s) between July 2017 and June 2018 in 924 general physi

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Dubois, Sydney, Richard Layese, Nicolas Limal, et al. "When is the use of intravenous immunoglobulin appropriate in immune thrombocytopaenia?" British Journal of Haematology, October 10, 2024. http://dx.doi.org/10.1111/bjh.19817.

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SummaryIntravenous immunoglobulin (IVIg) is the gold standard treatment for severe cases of immune thrombocytopaenia (ITP). However, its cost, limited duration of efficacy and market supply tension have led French guidelines to reserve IVIg for ITP patients with formal contra‐indications to corticosteroids, with French bleeding score (‘Khellaf score’) > 8, and corticosteroid‐resistant patients either with Khellaf score ≤ 8 or in preparation for an invasive procedure or during pregnancy. We studied the prescribing practices of IVIg for ITP in real‐life conditions and assessed their complianc

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Sá-Sousa, Ana, Rute Almeida, Ricardo Vicente, et al. "High oral corticosteroid exposure and overuse of short-acting beta-2-agonists were associated with insufficient prescribing of controller medication: a nationwide electronic prescribing and dispensing database analysis." Clinical and Translational Allergy 9, no. 1 (2019). http://dx.doi.org/10.1186/s13601-019-0286-3.

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Abstract Background Recurrent use of oral corticosteroids (OCS) and over-use of short-acting beta-2-agonists (SABA) are factors associated with adverse side effects and asthma-related death. We aim to quantify high OCS exposure, SABA over-use and its association with prescription and adherence to maintenance treatment for respiratory disease, among patients with prescriptions for respiratory disease, from the Portuguese electronic prescription and dispensing database (BDNP). Methods This was a 1-year (2016) retrospective population-based analysis of a random sample of adult patients from the B

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Eger, Katrien, Marijke Amelink, Simone Hashimoto, Pieter-Paul Hekking, Cristina Longo, and Elisabeth H. Bel. "Overuse of Oral Corticosteroids, Underuse of Inhaled Corticosteroids, and Implications for Biologic Therapy in Asthma." Respiration, September 14, 2021, 1–6. http://dx.doi.org/10.1159/000518514.

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<b><i>Background:</i></b> Asthma patients using high cumulative doses of oral corticosteroids (OCSs) are at risk of serious adverse events and are increasingly being treated with steroid-sparing asthma biologics. However, it is unknown whether prescribing these expensive biologics is always justified. <b><i>Objectives:</i></b> This study aimed to (1) assess the prevalence of asthma patients using high cumulative doses of OCSs, (2) explore the role of suboptimal inhaler therapy, and (3) estimate the proportion of patients to whom asthma biologics

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Carter, H., and C. Wood. "683 A Quality Improvement Project (QIP) To Increase Compliance with Peri-Operative Antibiotic Guidelines in Colorectal Surgery (CS)." British Journal of Surgery 108, Supplement_2 (2021). http://dx.doi.org/10.1093/bjs/znab134.468.

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Abstract Introduction In CS, the correct use of antibiotics is important in order to reduce the risk of surgical site and intra-abdominal infections, whilst balancing risks from overuse of antibiotics. The Commissioning for Quality and Improvement (CQUIN) of 2019/20 identified that antibiotic prophylaxis guideline compliance could be enhanced in CS. This QIP aimed to improve local CS antibiotic prophylaxis and extension guideline compliance. Method In December 2019, an educational session was held to highlight the details of the local guideline and prescribing discrepancies. A3 posters of the

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Alzaabi, Ashraf, Nasser Al Busaidi, Rohit Pradhan та ін. "Over-prescription of short-acting β2-agonists and asthma management in the Gulf region: a multicountry observational study". Asthma Research and Practice 8, № 1 (2022). http://dx.doi.org/10.1186/s40733-022-00085-5.

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Abstract Background The overuse of short-acting β2-agonists (SABA) is associated with poor asthma control. However, data on SABA use in the Gulf region are limited. Herein, we describe SABA prescription practices and clinical outcomes in patients with asthma from the Gulf cohort of the SABA use IN Asthma (SABINA) III study. Methods In this cross-sectional study conducted at 16 sites across Kuwait, Oman, and the United Arab Emirates, eligible patients (aged ≥ 12 years) with asthma were classified based on investigator-defined disease severity guided by the 2017 Global Initiative for Asthma repo

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Fung, Lydia WY, Vincent KC Yan, Christine Kwan та ін. "SABINA + Hong Kong: a territory wide study of prescribing trends and outcomes associated with the use of short-acting β2 agonists in the Chinese population". BMC Pulmonary Medicine 24, № 1 (2024). http://dx.doi.org/10.1186/s12890-024-03038-1.

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Abstract Background Excessive use of short-acting β2 agonists (SABA) in patients with asthma continues to be a notable concern due to its link to higher mortality rates. Global relevance of SABA overuse in asthma management cannot be understated, it poses significant health risk to patients with asthma and imposes burden on healthcare systems. This study, as part of global SABINA progamme, aimed to describe the prescribing patterns and clinical outcomes associated with SABA use in the Chinese population. Methods Retrospective cohort study was conducted using anonymized electronic healthcare re

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Esfahani, Zeinab, Ramin Abrishami, Seyed Ruhollah Mousavinasab, and Nazafarin Hatami-Mazinani. "A Drug Utilization Evaluation Study of Intravenous Acetaminophen in a Large Teaching Hospital." Journal of Pharmaceutical Care, February 18, 2020. http://dx.doi.org/10.18502/jpc.v7i4.2376.

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Background: Intravenous (IV) acetaminophen has become the most commonly chosen analgesic medication in critical care settings. Overall, the cost of the drug is higher than oral and rectal acetaminophen. As a result, numerous studies have been performed to evaluate the appropriateness of IV acetaminophen use based on guidelines. A lot of studies have shown that there is poor quality in compliance with guideline in developing countries. Current study aims to evaluate prescribing behavior of IV acetaminophen regimens in hospitalized adults in Tehran, Iran.  Methods: We enrolled 277 patients

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Dash, Sampa, Mohammad Ali, Eva Sultana, et al. "Healthcare seeking behavior and antibiotic use for diarrhea among children in rural Bangladesh before seeking care at a healthcare facility." Scientific Reports 15, no. 1 (2025). https://doi.org/10.1038/s41598-025-09479-w.

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Abstract Appropriate healthcare utilization and compliance with the WHO treatment guidelines can significantly reduce diarrhea-related childhood mortality and morbidity, while overuse of antibiotics notably increases antibiotic resistance. We studied care-seeking behavior and antibiotic use for childhood diarrhea by analyzing data from 8294 diarrheal episodes of 1–59-month-old children visiting a tertiary-care hospital in rural Bangladesh. Overall, 55% of the study children received antibiotics, while only 6% had dysentery. Notably, 77% of the antibiotics were obtained from a local pharmacy wi

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Khanina, A., N. Singh, R. James, D. C. M. Kong, M. A. Slavin, and K. A. Thursky. "Assessing the appropriateness of antifungal prescribing: key results from the implementation of a novel audit tool in Australian hospitals." Journal of Antimicrobial Chemotherapy, February 13, 2025. https://doi.org/10.1093/jac/dkaf044.

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Abstract Objectives To utilize the Antifungal National Antimicrobial Prescribing Survey (Antifungal NAPS), a novel tool utilizing international consensus metrics for antifungal stewardship, to assess the quality of systemic antifungal prescribing in Australian hospitals, in order to identify quality improvement targets. Methods Participating hospitals were directed to audit all systemic antifungals or focus on a specific antifungal drug or class. Data entry into the Antifungal NAPS online portal occurred between October 2022 and June 2023. The data collection tool comprised patient details, re

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Ljungquist, Ditte, Magnus Andersson, Marlene Areskog, and Anna-Maria Andersson. "Antibiotic Use in Dental Care of Dogs, Cats, and Rabbits in Sweden." Journal of Veterinary Dentistry, September 7, 2023. http://dx.doi.org/10.1177/08987564231189655.

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Antimicrobial resistance is one of the largest threats to global health. In society as well as in healthcare facilities, antimicrobial resistance is rapidly increasing with the main reason being overuse and misuse of antibiotics combined with inadequate infection prevention. For humans, dental care accounts for about 10% of all antibiotic prescriptions, making it an important target for antibiotic stewardship interventions. Corresponding figures for veterinary care are currently lacking but dental disease is frequently diagnosed in small animals. An important first step in the work towards pru

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Alshehhi, Hessa Saleh, Areeg Anwer Ali, Duaa Salem Jawhar, et al. "Assessment of implementation of antibiotic stewardship program in surgical prophylaxis at a secondary care hospital in Ras Al Khaimah, United Arab Emirates." Scientific Reports 11, no. 1 (2021). http://dx.doi.org/10.1038/s41598-020-80219-y.

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AbstractAntibiotic overuse is a major factor for causing antibiotic resistance globally. However, only few studies reported the implementation and evaluation of antimicrobial stewardship programs in Gulf Cooperation Council. This study was conducted within 8-months periods to evaluate the effect of the newly implemented antibiotic stewardship program on improving the prescribing practice of surgical antibiotic prophylaxis in a secondary care hospital in the United Arab Emirates by releasing local hospital guidelines. The data of 493 in patients were documented in the predesigned patient profil

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Kamal Khan, Jahanzeb, Syed Hasan Danish, Muhammad Nauman Shaikh, Rizwan Mahmud, Saima Shafqat, and Muhammad Usama. "Omeprazole (Risek®) Use in Inpatient and Outpatient Departments: A Post-marketing Surveillance Investigation." Pakistan Journal of Health Sciences, April 30, 2023, 122–27. http://dx.doi.org/10.54393/pjhs.v4i04.684.

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Proton pump inhibitors (PPIs) are widely used for the treatment of acid-related gastrointestinal disorders. However, their overuse or inappropriate prescription can lead to adverse effects, increased healthcare costs, and development of antibiotic-resistant infections. Objectives: To ascertain whether the Omeprazole (Risek®)-PPIs prescription patterns by practitioners in the inpatient and outpatient departments of various healthcare facilities in Pakistan are in compliance with the therapeutic indications and to evaluate the safety profile associated with each therapeutic indication. Methods:

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Poutanen, Roope, Matti Korppi, Peter Csonka, Satu-Liisa Pauniaho, Marjo Renko, and Sauli Palmu. "Use of antibiotics contrary to guidelines for children’s lower respiratory tract infections in different health care settings." European Journal of Pediatrics, July 19, 2023. http://dx.doi.org/10.1007/s00431-023-05099-6.

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AbstractThis study aimed to evaluate antibiotic prescriptions for children with lower respiratory tract infection (LRTI) in public and private primary care clinics and in a hospital’s pediatric emergency department (PED) in 2012–2013 (pre-guideline) and in 2014–2015 (post-guideline). Special attention was paid to guideline compliance, especially regarding macrolide prescriptions, which the guidelines discourage. Retrospective data of 1431 children with LRTI in November–December 2012–2015 were collected from electronic registers and checked manually. Three diagnostic groups were analyzed: commu

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Limato, Ralalicia, Erni J. Nelwan, Manzilina Mudia, et al. "A multicentre point prevalence survey of patterns and quality of antibiotic prescribing in Indonesian hospitals." JAC-Antimicrobial Resistance 3, no. 2 (2021). http://dx.doi.org/10.1093/jacamr/dlab047.

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Abstract Background The global emergence of antimicrobial resistance is driven by antibiotic misuse and overuse. However, systematic data in Indonesian hospitals to adequately inform policy are scarce. Objectives To evaluate patterns and quality indicators of antibiotic prescribing in six general hospitals in Jakarta, Indonesia. Methods We conducted a hospital-wide point prevalence survey (PPS) between March and August 2019, using Global-PPS and WHO-PPS protocols. The analysis focused on antibacterials (antibiotics) for systemic use. Results Of 1602 inpatients, 993 (62.0%) received ≥1 antimicr

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Sana Iftikhar and Shahid Mahmood Sethi. "PENICILLIN: A JOURNEY FROM A MAGIC BULLET TO A RESISTANT DRUG." JAIMC: Journal of Allama Iqbal Medical College 20, no. 1 (2022). http://dx.doi.org/10.59058/jaimc.v20i1.16.

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The year 2022 marked the 81st anniversary of first systemic administration of Penicillin in humans. It was undoubtedly a biggest milestone and a game changer in practice of modern medicine. The discovery of Penicillin was a lucky mistake happened in 1928. Dr Alexander Fleming, an English bacterio- logist working in St.marry’s Hospital London left his laboratory for holidays leaving few of his petri dishes openly near window on a bench. Upon his return from holidays few days later, while sorting out these Petri dishes, he realized that in one of these dishes colony of staphylococci bacteria was

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