Academic literature on the topic 'Cosmetic active ingredients'
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Journal articles on the topic "Cosmetic active ingredients"
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Siahaan, Evi Amelia, Agusman, Ratih Pangestuti, Kyung-Hoon Shin, and Se-Kwon Kim. "Potential Cosmetic Active Ingredients Derived from Marine By-Products." Marine Drugs 20, no. 12 (November 24, 2022): 734. http://dx.doi.org/10.3390/md20120734.
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The market demand for marine-based cosmetics has shown a tremendous growth rate in the last decade. Marine resources represent a promising source of novel bioactive compounds for new cosmetic ingredient development. However, concern about sustainability also becomes an issue that should be considered in developing cosmetic ingredients. The fisheries industry (e.g., fishing, farming, and processing) generates large amounts of leftovers containing valuable substances, which are potent sources of cosmeceutical ingredients. Several bioactive substances could be extracted from the marine by-product that can be utilized as a potent ingredient to develop cosmetics products. Those bioactive substances (e.g., collagen from fish waste and chitin from crustacean waste) could be utilized as anti-photoaging, anti-wrinkle, skin barrier, and hair care products. From this perspective, this review aims to approach the potential active ingredients derived from marine by-products for cosmetics and discuss the possible activity of those active ingredients in promoting human beauty. In addition, this review also covers the prospect and challenge of using marine by-products toward the emerging concept of sustainable blue cosmetics.
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Dwicesaria, Maheswari Alfira, Mega Safithri, Dimas Andrianto, and Ukhradiya Magharaniq Safira Purwanto. "Halal enzymatic cosmetic ingredients: The role of enzymes in ingredients selection." Halal Studies and Society 1, no. 1 (December 4, 2023): 16–19. http://dx.doi.org/10.29244/hass.1.1.16-19.
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The rising demand for halal products, especially within the cosmetics industry, has increased the need for cosmetic products to comply with Islamic laws. One of the challenges in achieving halal certification is the determination of the source of the active ingredients used in cosmetic products, such as enzymes. According to Islamic laws, enzymes derived from pigs or other animals that are not slaughtered are not considered halal. To ensure that the enzymes used in cosmetics are derived from halal sources, it is necessary to use enzymes generated from microorganisms through fermentation, provided that the raw materials and growth medium comply with Islamic laws. Additionally, halal cosmetics must meet regional and international standards, including the Indonesian Ulema Council’s Fatwa and the Malaysian Cosmetic and Personal Care Standards. This research provides a comprehensive review of the role of enzymes in selecting halal compliance cosmetic ingredients, focusing on the source of enzymes as a means of assessing the halalness of cosmetic products. It is essential to utilize halal enzymes such as those derived from plants to provide Muslim consumers with assurance when using cosmetic products.
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Dwicesaria, Maheswari Alfira, Mega Safithri, Dimas Andrianto, and Ukhradiya Magharaniq Safira Purwanto. "Halal enzymatic cosmetic ingredients: the role of enzymes in ingredients selection." Halal Studies and Society 1, no. 1 (December 9, 2023): 23–27. http://dx.doi.org/10.29244/hass.1.1.23-27.
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The large Muslim population in the world lead to an increasing demand for halal products. One of the halal products that is still difficult to determine is cosmetic products. The cosmetics industry is still dominated by non-halal products. One of the active ingredients that is currently popular is the use of enzymes. Many enzymes that isolated from living organisms come from pigs or halal animals that are not slaughtered according to the Islamic law. Ensuring that enzymes used in cosmetics are derived from halal sources is mandatory for achieving halal certification. Cosmetic enzymes generated from microorganisms through fermentation can be considered halal if the raw materials and growth medium are halal-compliant. Compliance with regional and international standards, such as the Indonesian Ulema Council's Fatwa and the Malaysian Cosmetic and Personal Care Standard, is crucial for halal cosmetics. This article aims to provide a comprehensive review of the role of enzymes in the selection of Halal-compliant cosmetic ingredients. The source of the enzymes employed is one approach to assess the halalness of cosmetic products. The utilization of halal enzymes is necessary to give Muslims assurance while using a cosmetic product. Enzymes that are considered halal are enzymes that sourced from plants.
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Roniawati, Irna, Norisca Aliza Putriana, Adinda Naswa Putri, and Yuniar Alfain Nur’aini. "Review: Saffron’s Activity as an Active Ingredient in Cosmetics." Indonesian Journal of Pharmaceutics 3, no. 2 (November 3, 2021): 74. http://dx.doi.org/10.24198/idjp.v3i2.34876.
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Saffron (Crocus sativus) is a plant that has been widely used in Asia, especially in the health sector. This can be related to other than that saffron is also known for its use as a cosmetic because Saffron has various kinds of pharmacological activities beneficial to human skin. Today's cosmetic users prefer cosmetics with herbal or natural ingredients, especially in Indonesia. This happens because it is considered that herbal cosmetics are safer and harmless in long-term use. Therefore, it is necessary to do related act ivities of saffron as a cosmetic ingredient. This is narrative research where the data is obtained from PubMed, Science Direct, and Google Scholar with keywords Saffron, Saffron for cosmetics, and others. There were eight references, with inclusion criteria being national and international journals and national websites published in 2011-2021, especially regarding the study of saffron activity as an ingredient for cosmetics. Then the data is analyzed narratively. It was found that Saffron (Crocus sativus) contains compounds that have a cosmetic activity such as safranal which can be used as a perfume, crocin as an antioxidant and as anti-dark spot, crocin, safranal, and crocetin as anti-UV, crocin, and crocetin as an anti-inflammatory and as coloring pigment in cosmetics, vitamin C, flavonoids and zinc as a face toner, kaempferol, crocin and crocetin as anti-wrinkle, zeaxanthin, lycopene, carotene, crocetin, picrocrocin, kaempferol, and crocin as anti-aging. Saffron (Crocus sativus) has various beneficial activities for the skin, so it can be used as an ingredient in making cosmetics.Keywords : Cosmetics, Herbal, Saffron, Herbal Cosmetics, Active Ingredient
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Pagels, Fernando, Cíntia Almeida, Vitor Vasconcelos, and A. Catarina Guedes. "Cosmetic Potential of Pigments Extracts from the Marine Cyanobacterium Cyanobium sp." Marine Drugs 20, no. 8 (July 27, 2022): 481. http://dx.doi.org/10.3390/md20080481.
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The current mindset in the cosmetics market about sustainable ingredients had increased the search for new sources of natural active ingredients. Cyanobacteria are a great source of functional ingredients for cosmetics, as a producer of pigments with described bioactive potential (carotenoids and phycobiliproteins). This work aimed to evaluate the cosmetic potential of marine cyanobacterium Cyanobium sp. pigment-targeted extracts (carotenoids and phycobiliproteins), evaluating their in vitro safety through cytotoxicity assays, cosmetic-related enzyme inhibition, ingredient stability, and putative product (serum formulation). Results showed no cytotoxicity from the extracts in skin-related cell lines. Carotenoid extract showed anti-hyaluronidase capacity (IC50 = 108.74 ± 5.74 mg mL−1) and phycobiliprotein extract showed anti-hyaluronidase and anti-collagenase capacity (IC50 = 67.25 ± 1.18 and 582.82 ± 56.99 mg mL−1, respectively). Regarding ingredient and serum stability, both ingredients showed higher stability at low-temperature conditions, and it was possible to maintain the pigment content and bioactive capacity stable during the tested period, although in higher temperatures the product was degraded in a week. As a major conclusion, both extracts can be potential natural and sustainable ingredients for cosmetic uses, with relatively simple formulation and storage, and can be promising natural anti-aging ingredients due to their bioactive capacity.
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Plainfossé, Hortense, Pauline Burger, Grégory Verger-Dubois, Stéphane Azoulay, and Xavier Fernandez. "Design Methodology for the Development of a New Cosmetic Active Based on Prunus domestica L. Leaves Extract." Cosmetics 6, no. 1 (January 29, 2019): 8. http://dx.doi.org/10.3390/cosmetics6010008.
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When it comes to the development of new active ingredients for cosmetics, biodiversity is a rich source for inspiration that must be tapped in a sustainable manner to cause no social nor ecological damage. Agri-food by-products are therefore more and more considered as available biomass that can be reused to extract their maximum value to produce new cosmetic ingredients before returning to the biosphere. The process to transform plant waste materials into powerful cosmetic actives is thoroughly described in the present paper via the example of the design of a liquid anti-aging ingredient based on a Prunus domestica L. extract obtained by maceration of plums’ dried leaves in propylene glycol. The subsequent development of an SPE (solid-phase extraction) methodology used to remove the propylene glycol to get access to the extracted molecules is thoroughly described as a means to follow the stability of the ingredient over time once formulated into a finished product.
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Morais, Tiago, João Cotas, Diana Pacheco, and Leonel Pereira. "Seaweeds Compounds: An Ecosustainable Source of Cosmetic Ingredients?" Cosmetics 8, no. 1 (January 15, 2021): 8. http://dx.doi.org/10.3390/cosmetics8010008.
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Seaweed-based cosmetics are being gradually used by consumers as a substitute of synthetic equivalent products. These seaweed-based products normally contain purified compounds or extracts with several compounds. Several seaweeds’ molecules already demonstrated a high potential as a cosmetic active ingredient (such as, mycosporine-like amino acids, fucoidan, pigments, phenolic compounds) or as a key element for the products consistency (agar, alginate, carrageenan). Moreover, seaweeds’ compounds present important qualities for cosmetic application, such as low cytotoxicity and low allergens content. However, seaweeds’ biochemical profile can be variable, and the extraction methods can cause the loss of some of the biomolecules. This review gives a general look at the seaweed cosmetics benefits and its current application in the cosmetic industry. Moreover, it focuses on the ecological and sustainable scope of seaweed exploitation to guarantee a safe source of ingredients for the cosmetic industry and consumers.
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Hamdy A, Shaaban. "Potential Use of Essential Oils and Their Individual Components in Cosmeceuticals: A Review." Annals of Biomedical Science and Engineering 7, no. 1 (September 7, 2023): 031–37. http://dx.doi.org/10.29328/journal.abse.1001023.
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The cosmetic industry is searching for new active ingredients from renewable natural sources to make more environmentally friendly and safe products. Botanical extract is a nearly limitless source of these new actives due to the current consumer demands as well as international regulations. Due to both their fragrant nature for the creation of fragrances and perfumes and the numerous advantageous properties of their individual components (EOCs), such as anti-inflammatory, antimicrobial, and antioxidant properties, essential oils (EOs) emerge as a very common natural ingredient in cosmetics and toiletries. Additionally, nowadays, the cosmetic industry includes EOs or different mixtures of their individual components (EOCs), either as active ingredients or as preservatives, in various product ranges (e.g., moisturizers, lotions, and cleansers in skin care cosmetics; conditioners, masks or anti-dandruff products in hair care products; lipsticks, or fragrances in perfumery). However, because each essential oil’s distinct chemical profile is linked to a different set of advantages, it is challenging to generalize about how they might be used in cosmetics and toiletries. Formulators frequently spend time looking for appropriate combinations of EOs or EOCs to achieve particular advantages in the finished products. The literature on the most recent developments in the use of EOs and EOCs in the production of cosmetic products is updated in this work’s review of the literature. Additionally, certain particular issues pertaining to the security of EOs and EOCs in cosmetics will be covered. It is expected that the information contained in this comprehensive review can be exploited by formulators in the design and optimization of cosmetic formulations containing EOs.
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Kabat, Małgorzata, Justyna Popiół, and Agnieszka Gunia-Krzyżak. "Cinnamic Acid Derivatives as Potential Multifunctional Agents in Cosmetic Formulations Used for Supporting the Treatment of Selected Dermatoses." Molecules 29, no. 23 (December 9, 2024): 5806. https://doi.org/10.3390/molecules29235806.
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Cinnamic acid and its natural derivatives were primarily used in cosmetics as fragrance materials as well as skin and hair conditioners. Nowadays, not only natural but also synthetic cinnamic acid derivatives are used as active ingredients of cosmetic formulations. They still serve as fragrance ingredients but also as active ingredients supporting the treatment of selected dermatoses such as acne vulgaris, atopic dermatitis, and hyperpigmentation. They are also commonly used in anti-aging cosmetic formulations. On the other hand, several cinnamic acid derivatives used as fragrances in cosmetic products are classified as potential allergens which can cause contact dermatitis. The main mechanisms of action proved for various cinnamic acid derivatives include antioxidant, antimicrobial, anti-inflammatory, and antimelanogenic properties. Most commonly used cinnamic acid derivatives in cosmetics products are hydroxy acids such as ferulic acid, caffeic acid, p-coumaric acid, and sinapic acid. Chemical synthesis led to several modified acids, esters, and amides, which also showed the potential to be used in cosmetic formulations.
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Kowalczyk, Sławomir, Mirosława Grymel, Janusz Bilik, Wiktoria Kula, Agata Wawoczny, Paulina Grymel, and Danuta Gillner. "Selected Plants as Sources of Natural and Active Ingredients for Cosmetics of the Future." Applied Sciences 14, no. 8 (April 20, 2024): 3487. http://dx.doi.org/10.3390/app14083487.
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A clear trend of replacing synthetic cosmetic ingredients with natural ones can be observed in modern cosmetology. This entails the need to search for bioactive ingredients in the natural environment, especially in plants. This paper presents a comprehensive overview of dermatological, cosmetic, and pharmacological properties of highly potent plants, namely Acmella oleracea (A. oleracea), Centella asiatica (C. asiatica), Psoralea corylifolia (P. corylifolia), Plantago lanceolata L. (P. lanceolata L.), and Solidago virgaurea L. (S. virgaurea L.). Biological activity and phytochemical constituents are presented for all plants, but special attention is paid to ingredients of particular value to the cosmetics industry. The advantages of spilanthol and bakuchiol as a replacement for the popular botulinum toxin and retinol are discussed. Natural habitats, ethnomedical importance, cultivation area, as well as extraction methods of active plant ingredients are presented in detail. A wide spectrum of biological activity indicates the enormous potential of the presented plants in formulating new cosmetic and dermatological preparations.
Dissertations / Theses on the topic "Cosmetic active ingredients"
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Mattiasson, Johanna. "Method development of an in vitro vertical Franz diffusion cell system to assess permeation of cosmetic active ingredients." Thesis, Uppsala universitet, Institutionen för kemi - Ångström, 2020. http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-414205.
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For evaluation of potential skincare ingredients, an in-house method using Static Franz diffusion cells and dialysis membranes was developed. Benzoic acid was chosen as a model substance along with L-ascorbic acid and α-Tocopherol. The cell conditions were tailored to encourage transmembrane diffusion. Benzoic acid was tested in acetate buffer (pH 4.6), which yielded a maximum flux of 0.91 ± 0.03 mg ∙ cm-2 ∙ h-1 and absorption of 103 ± 4 % out of the applied dose after 8 h. There were strong indications that benzoic acid ionization must be suppressed by lower pH to increase penetration rates. L-ascorbic acid yielded a flux of 0.29 ± 0.01 mg ∙ cm-2 ∙ h-1 in phosphate buffered saline (PBS, pH 7.4) and absorption of 87 ± 7 % of the applied dose after 8 h. Experiments with α-tocopherol showed no penetration in PBS with added bovine serum albumin (BSA), leading to the hypothesis that more hydrophobic membranes and/or receptor medium are needed for the study of lipophilic compounds. In addition, the release of benzoic acid from the amorphous mesoporous magnesium carbonate Upsalite® was investigated. The results showed significant release and penetration of benzoic acid from the solid matrix in both acetate buffer and PBS. The maximum flux was estimated to 6.61 ± 0.96 mg ∙ cm-2 ∙ h-1 in acetate buffer and 99 ± 9 % of the applied dose was absorbed after 3h. Tests of Upsalite with benzoic acid on hydrophobic silicone and Strat-M membranes showed no significant penetration, likely due to insufficient wetting of the sample. Pre-wetting of Strat-M membrane lead to penetration of benzoic acid into the membrane. Flux rates achieved on synthetic membranes are generally much higher compared to skin, which results in this thesis show. In conclusion, data for pure benzoic acid and L-ascorbic acid in the developed method using dialysis membranes showed reasonable agreement with literature. Penetration of benzoic acid is pH-dependent and may be either increased or decreased by choice of skin model or by using Upsalite as vehicle. Choosing a buffer pH below the pKa of the substance may enhance penetration. Introducing L-ascorbic acid in Upsalite could potentially increase the permeation, similar to that of benzoic acid.
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Sena, Luigi Michele. "Hairy root culture as source of novel plant-derived active compounds with applications in cosmetics." Doctoral thesis, Universita degli studi di Salerno, 2015. http://hdl.handle.net/10556/1954.
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2013 - 2014Hyperpigmentation is the process by which an excess of melanin is produced by the skin. Typically, hyperpigmentation occurs as a result of stress, damage or prolonged inflammation of the skin. The most common cause is sun damage, though hyperpigmentation is often a consequence of inflammation following acne, eczema, psoriasis, dermatitis etc. Hyperpigmentation may also occur in the skin due to hormonal changes in the body typically associated with pregnancy or the taking of oral contraception. Beside this medical aspects, the global skin depigmenting product market has been forecast to reach a value of $19.8 billion by 2018, driven by the growing desire for light-coloured skin among both men and women primarily from the Asian, African and Middle East regions. Although products do exist that can actually bleach the skin, these products contain dangerous or toxic ingredients (such as hydroquinone and mercury) and are banned in most countries. Blocking or reducing the accumulation of melanin in the skin can be obtained either by switching off one or more components of the pathway that go from the receptor activation to the enzymatic inhibition of melanin formation catalyzed by the tyrosinase. For this purpose, several antimelanogenic reagents have been developed and discovered nowadays. However, only a few of these inhibitors have been introduced and used due to their problems in cytotoxicity (affecting the cell growth and survival), selectivity, solubility and stability. The present project was aimed at identifying new total plant extracts exerting beneficial effects in skin care, with special emphasis on the development of novel plant-derived actives with hypopigmenting effects. Experimental activities were carried out in collaboration with Arterra Bioscience S.r.l, in the frame of the programme “Dottorato di Ricerca in Azienda”, funded by European Commission and Regione Campania (POR Campania FSE 2007-2013). Arterra is an Italian research-based Biotech company mostly involved in developing new plant-derived extracts to be used as active ingredients with cosmetic application. Hairy root cultures of three different plant species (Cichorium intybus, Brassica rapa subsp. pekinensis and Helianthus annuus) were generated. Hairy roots of Brassica rapa subsp. pekinensis were selected for further studies on the base of a preliminary screening for anti-oxidant activity of a total crude ethanol extract and a sugar/peptides mixture derived from cell walls, coupled to an active growth. Crude ethanol extract and a sugar/peptides mixture derived from cell wall of Brassica rapa subsp pekinensis hairy roots were tested in murine melanoma cells (B16-F1) and human epidermal melanocytes isolated from lightly pigmented adult skin (HEMa-LP), by using a panel of in vitro and in vivo biological assays to assess their role in modulating melanogenesis. Both extracts at different concentrations demonstrated to inhibit the cellular tyrosinase, a key enzyme in melanin production, and to reduce melanin content in murine melanoma cells. In addition, the sugar/peptides mixture of Brassica rapa susp. pekinensis hairy roots significantly inhibited the levels of cyclic adenosine monophosphate (cAMP), an important second messenger within melanogenesis signalling pathway. Furthermore, the same extract significantly decreased the expression of microphtalmia-associated transcription factor (MITF) and its promoter activity of about 30%, analyzed by in vitro reporter (luc+)-assay. Altogether these data indicates that the sugar/peptides mixture isolated from cell wall of Brassica rapa subsp. pekinensis hairy roots might exert its inhibitory effect on melanogenesis through the downregulation of MITF transcription. Furthermore, Brassica rapa subsp. pekinensis ethanol extract was able to enhance the expression levels of important genes encoding for proteins involved into extracellular matrix (ECM) assembly. Finally, a competitive industrial production hairy-root based platform was developed by Brassica rapa subsp. pekinensis hairy root biomass scaling-up and improved extraction procedures. Overall, these results, under pending patent application, will contribute to introduce product and process innovations at Arterra Bioscience s.r.l, for the identification of new and safer plant-derived melanogenesis inhibitors. In general, the developed industrial production platform will be also extended to the screening of actives from other plant species and to the release of novel plant-derived products in different segments of the cosmetic market. [edited by author]
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Silva, Diana Patrícia Pinto da. "Nanopartículas lipídicas: aplicações cosméticas." Master's thesis, [s.n.], 2013. http://hdl.handle.net/10284/4484.
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Projeto de Pós-Graduação/Dissertação apresentado à Universidade Fernando Pessoa como parte dos requisitos para obtenção do grau de Mestre em Ciências FarmacêuticasTendo em conta a sua composição e as vantagens que apresentam, as nanopartículas lipídicas têm sido amplamente aplicadas em cosmetologia, existindo atualmente vários produtos comercializados. Deste modo, a análise das potencialidades destes sistemas para novas aplicações cosméticas é essencial. Neste trabalho é efetuada uma revisão bibliográfica relativa aos diferentes produtos cosméticos contendo nanopartículas lipídicas, quer estes se encontrem em fase de estudo ou já disponíveis no mercado. Na primeira parte do trabalho é feita uma breve introdução acerca da estrutura da pele, da definição de produtos cosméticos e das suas principais caraterísticas e aplicações. Na segunda parte são descritos os sistemas de nanopartículas lipídicas, tendo em conta as suas caraterísticas estruturais, diferentes aplicações em cosmetologia e são dados exemplos dos produtos cosméticos existentes no mercado. According to their composition and advantages, lipid nanoparticles have been widely applied in cosmetology, and there are several products that can be found on the market nowadays. Therefore, the analysis of the potential of these new systems for cosmetic applications is essential. In this work is performed a literature review about the diverse cosmetic products containing lipid nanoparticles, whether they are in clinical trials or already in the market. In the first part, a brief introduction regarding the structure of the skin, the definition of cosmetic products, their main characteristics and applications are presented. In the second part are described the lipid nanoparticles systems, considering their structural characteristics, different applications in cosmetology and are given some examples of the cosmetic products that are already on the market.
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Vieytez, Maria. "Nouveaux actifs cosmétiques issus d'extraits végétaux : caractérisation phytochimique, propriétés physicochimiques et activités biologiques." Electronic Thesis or Diss., Université Côte d'Azur, 2024. http://www.theses.fr/2024COAZ5068.
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La demande croissante des consommateurs pour des produits naturels incite les fabricants de produits cosmétiques à prioriser le développement de nouveaux ingrédients actifs naturels. Ce projet, réalisé en collaboration avec le Centre d'Innovation Europe de Shiseido, l'Unité de Catalyse et Chimie du Solide (UCCS), et l'Institut de Chimie de Nice (ICN), se concentre sur le développement d'ingrédients actifs cosmétiques issus de plantes françaises. Une méthodologie de sélection des plantes a été établie, prenant en compte la conformité aux cadres réglementaires internationaux, l'approvisionnement local en France, ainsi que le potentiel d'innovation de chaque plante. Parmi une liste initiale de 1 614 plantes candidates, 19 ont été retenues pour des extractions et analyses de leurs profils phytochimiques et de leurs activités biologiques in vitro. Des tests chimiques, tels que le DPPH, et des tests enzymatiques, comme l'anti lipoxygénase, ont permis d'évaluer leur potentiel cosmétique. Deux plantes se sont révélées particulièrement différenciantes et innovantes, en raison de leurs activités biologiques peu explorées et/ou des composés non identifiés responsables de ces effets. L'effet des extraits sur l'expression génétique des kératinocytes épidermiques humains normaux a confirmé le potentiel d'application cosmétique. Par ailleurs, des techniques de caractérisation physicochimique, telles que la mesure de la tension de surface et l'évaluation du pouvoir antioxydant, ont enrichi cette étude. Une partie des composés bioactifs présents dans ces deux plantes ont été détectés et identifiés en recourant à diverses techniques analytiques et spectroscopiques telles HPLC, HPTLC, GC et HRMS. Au regard de son potentiel, la plante la plus prometteuse parmi les deux a fait l'objet d'une étude phytochimique approfondie via un fractionnement bioguidé, permettant d'isoler et identifier certains des composés actifs tels que des ellagitannins, flavonoïdes et saponines. Enfin, pour établir une méthode de production fiable et à grande échelle de l'extrait racinaire de cette plante, une étude de faisabilité a été réalisée en collaboration avec Futura Gaia, utilisant un système de géoponie rotative. Les conditions de culture ont été optimisées selon des principes de bioinspiration, ce qui a conduit à un protocole garantissant un approvisionnement local et répétable en racines. Cette étude a notamment permis d'obtenir un extrait avec un rendement d'extraction deux fois supérieur, tout en maintenant la qualité de la plante, avec un profil phytochimique et des activités biologiques inchangés par rapport à un témoin cultivé horizontalementThe trend towards natural products and the growing consumer demand for greater efficacy of skincare products have made developing new natural active ingredients a top priority for cosmetics manufacturers. This work, conducted in collaboration with Shiseido's Europe Innovation Center, the Unité de Catalyse et Chimie du Solide (UCCS) from Centrale Lille Institut, and the Institut de Chimie de Nice (ICN), focuses on the development of bioinspired active ingredients derived from French plants. A plant selection methodology was implemented taking into account compliance with international regulatory frameworks, local sourcing in France, and the innovation potential of each plant. From an initial list of 1,614 candidate plants, 19 were sourced and thoroughly studied, through extraction and analysis of their phytochemical profiles and in vitro biological activities. Chemical assays, such as DPPH, and enzymatic assays, such as anti-lipoxygenase, were used to assess the biological activities and accordingly the cosmetic potential of each extract. Two plants emerged as particularly distinctive and innovative due to their underexplored biological activities and/or unidentified compounds responsible for these effects. The impact of the extracts on the gene expression of normal human epidermal keratinocytes confirmed their cosmetic application potential. Additionally, physicochemical characterization techniques, such as surface tension measurement and antioxidant capacity assessment, enriched this study. Some of the bioactive compounds present in these two plants were detected and identified using various analytical and spectroscopic techniques, including HPLC, HPTLC, GC, and HRMS. Given its potential, the most promising plant among the two underwent an in-depth phytochemical study through guided fractionation, allowing for the isolation and identification of active compounds such as ellagitannins, flavonoids, and saponins. Finally, to establish a reliable and scalable production method for the root extract of this plant, a feasibility study was conducted in collaboration with Futura Gaia, utilizing a rotating geophonic system. The cultivation conditions were optimized based on bioinspiration principles, leading to a protocol that ensures local and repeatable sourcing of roots. This study notably resulted in an extract with an extraction yield twice as high, while maintaining the quality of the plant, with an unchanged phytochemical profile and biological activities compared to a horizontally cultivated control
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Santos, Cláudia Maria Pereira dos. "Nanoencapsulação de ingredientes activos em cosmetologia." Master's thesis, [s.n.], 2012. http://hdl.handle.net/10284/3737.
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Projeto de Pós-Graduação/Dissertação apresentado à Universidade Fernando Pessoa como parte dos requisitos para obtenção do grau de Mestre em Ciências FarmacêuticasA aplicação de produtos cosméticos na pele apresenta limitações, devido sobretudo à dificuldade dos ingredientes activos em atravessarem o estrato córneo. Por outro lado, é importante garantir que estes não atinjam a circulação geral. Neste sentido, várias estratégias têm sido desenvolvidas e investigadas para contornar o problema, designadamente, o uso de nanossistemas para encapsular e vectorizar os ingredientes activos. A nanoencapsulação de ingredientes activos em cosmetologia tem sido descrita como promissora, devido às vantagens que apresenta para as substâncias encapsuladas: (i) aumento da estabilidade; (ii) libertação controlada; (iii) direccionamento para locais específicos; (iv) promoção da penetração cutânea. Adicionalmente, o uso de nanossistemas por si só permite obter efeitos benéficos ao nível da pele: (i) manutenção da integridade da barreira cutânea; (ii) aumento da eficácia e tolerância dos filtros solares à superfície; (iii) obtenção de produtos mais atractivos do ponto de vista estético. Este trabalho tem como objectivo efectuar uma revisão bibliográfica relativa à nanoencapsulação de ingredientes activos em cosmetologia. Inicialmente é efectuada uma abordagem relativa à anatomia e histologia da pele. De seguida, são descritos os diversos nanossistemas com aplicações em cosmetologia, indicando-se as suas vantagens e limitações. Os resultados publicados nos últimos anos pela comunidade científica, bem como as preparações actualmente existentes no mercado e as perspectivas futuras desta aplicação são referidos. The application of cosmetics on the skin shows some drawbacks, mainly because of limitations of the active ingredients to cross the stratum corneum barrier. On the other hand, is important to assure that these substances do not reach systemic circulation. Therefore, several strategies have been developed in order to circumvent the problem, namely, the use of nanosystems for the encapsulation and target the active ingredients. The nanoencapsulation of cosmetic active ingredients have been described as very promising, because of the advantages that presents for the encapsulated substances: (i) improved stability; (ii) controlled release; (iii) local target; (iv) skin penetration enhancement. Moreover, the use of empty nanosystems exerts skin benefits: (i) improvement of barrier integrity; (ii) promotion of the efficacy and tolerability of sun filters; (iii) achievement of more esthetic attractive products.
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Westfall, Alexandra. "Evaluation of the Efficacy of Anthocyanins as Biologically Active Ingredients in Lipstick Formulations." The Ohio State University, 2015. http://rave.ohiolink.edu/etdc/view?acc_num=osu1429170218.
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Ruivo, Adriana Pessoa. "Envelhecimento cutâneo: fatores influentes, ingredientes ativos e estratégias de veiculação." Master's thesis, [s.n.], 2014. http://hdl.handle.net/10284/4413.
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Projeto de Pós-Graduação/Dissertação apresentado à Universidade Fernando Pessoa como parte dos requisitos para obtenção do grau de Mestre em Ciências FarmacêuticasO envelhecimento é um processo de degradação progressiva e diferencial que ocorre em todos os órgãos e desta forma a pele não lhe fica indiferente. O envelhecimento cutâneo pode ser intrínseco ou cronológico, aquele que surge com a idade influenciado por fatores genéticos, ou extrínseco ou actínico aquele que surge influenciado por fatores externos tal como o tabaco, poluição, hábitos de vida e predominantemente, a radiação solar (fotoenvelhecimento). Surgem, com a idade, alterações bioquímicas que conduzem a manifestações clínicas ao nível cutâneo, como rugas, aumento de espessura, pigmentações, entre outras. Algumas dessas alterações, encontram-se ao nível das funções do sistema imunitário, dos anexos cutâneos, da reparação do DNA e também do balanço de espécies oxidantes e antioxidantes surgindo geralmente stress oxidativo, estas por serem cumulativas agravam e antecipam o processo de envelhecimento. Existem, atualmente, alguns ingredientes e metodologias eficazes na melhoria de sinais de envelhecimento, designadamente, as vitaminas A, E e C, coenzima Q10, retinoides, compostos fitoterápicos como os alfa-hidroxi-ácidos (AHA), ou derivados da soja. No que respeita a metodologias, existem igualmente algumas com eficácia comprovada como os peeling’s químicos, o botox ou toxina botulínica, os fillers ou preenchimentos. Sendo esta uma área em constante investigação, existem analogamente, muitos estudos em desenvolvimento, havendo algumas novidades neste âmbito, principalmente ao nível de ingredientes ativos, destacando-se os péptidos. Relativamente a veículos, geralmente, são produtos em forma de emulsão (cremes, por exemplo), existindo já novidades nesse âmbito como, por exemplo, as nano e micropartículas, lipossomas, nano e microemulsões e as ciclodextrinas. O presente trabalho pretende elucidar e abordar todos os pontos supramencionados, de forma pormenorizada auxiliando a uma melhor compreensão do envelhecimento cutâneo. Aging is a process of gradual and differential degradation that occurs in all organs and the skin is not different. Skin aging can be intrinsic or chronological, one that comes with age influenced by genetics, or extrinsic or actinic that appears influenced by external factors such as tobacco, pollution, lifestyle and solar radiation (Photoaging), predominantly. Aging increases modified processes that lead to visual clinical changes in the skin such as wrinkles, increased thickness, and pigmentation among others. These changes occur in the immune system, skin appendages, DNA repair and also in the balance of oxidant and antioxidant species that generally causes oxidative stress. These processes are cumulative, and that worsens and anticipates the aging process. Currently, there are some ingredients and effective methodologies that improve signs of aging, notably, vitamins A, C and E, coenzyme Q10, retinoids, herbal compounds such as alpha hydroxy acids (AHA) and soy products. Regarding to methods, there are also some with proven efficacy such as: chemical peels, botulinum toxin and fillers. Aging cosmetics is an area of constant research, there are similarly many studies in development, with some news in this field, especially in terms of active ingredients, like peptides. Vehicles are usually in the form of emulsion products (creams, for example), and may include, for example, nano and microparticles, liposomes, nano and microemulsions and cyclodextrins. The present work aims to elucidate and review all the above in detail for a better understanding of aging cosmetic science.
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Janvier, Xavier. "Etude de l'effet d'un polluant atmosphérique (NO2) sur le microbiote cutané Dialog between skin and its microbiota : Emergence of "Cutaneous bacterial endocrinology" Deleterious effects of an air pollutant on a selection of commensal skin bacterial strains, potential contributor to dysbiosis Response of a commensal skin bacterium to nitrogen oxides (NOx), air pollutants : potential tools for testing anti-pollution active cosmetic ingredient effectiveness Draft genome sequence of the commensal strain Corynebacterium tuberculostearicum CIP 102622 isolated from human skin Draft genome sequences of four commensal strains of Staphylococcus and Pseudomonas isolated from healthy human skin." Thesis, Normandie, 2021. http://www.theses.fr/2021NORMR007.
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Le dioxyde d’azote (NO2), en tant que second polluant atmosphérique le plus meurtrier en Europe est un des plus préoccupants pour la santé humaine selon l’Agence Européenne de l’Environnement. Il est notamment connu pour être responsable de maladies cardiovasculaires, respiratoires ainsi que pour contribuer au vieillissement cutané et au développement de la dermatite atopique. Des facteurs endogènes à l’hôte tels que le microbiote cutané interviennent également dans cette pathologie. En effet, de nombreuses pathologies cutanées sont corrélées à un déséquilibre (dysbiose) du microbiote bactérien, un acteur essentiel du maintien de l’homéostasie de la peau. Or, il est fortement soupçonné que l’effet des polluants sur la peau implique des mécanismes d’action directe mais également un mécanisme d’action indirecte lié à l’altération du microbiote cutané par le polluant. En conséquence, il est pertinent d’aborder l’effet du NO2 gazeux (gNO2) sur le microbiote cutané bactérien. Cette thèse a donc pour objectif d’évaluer l’impact physiologique, morphologique et moléculaire du NO2 sur des souches bactériennes commensales d’espèces représentatives du microbiote cutané (Staphylococcus aureus, Staphylococcus epidermidis, Staphylococcus capitis, Pseudomonas fluorescens, Corynebacterium tuberculostearicum). Selon l’espèce, des réponses différentes au stress nitrosant généré par le gNO2 ont ainsi été mises en évidence ainsi qu’une tolérance plus importante au gNO2 pour certaines d’entre elles. Ces travaux suggèrent par conséquent que le NO2 pourrait contribuer à la formation d’un état dysbiotique du microbiote cutané et participer à l’action indirect du polluant sur la peauNitrogen dioxide (NO2), as the second most deadly air pollutant in Europe, is one of the most of concern for human health according to the European Environment Agency. It is notably known to be responsible for cardiovascular and respiratory diseases and also contributes to skin aging and atopic dermatitis. Host endogenous factors such as the cutaneous microbiota are also involved in this pathology, which is common in urban and suburban areas. Indeed, many skin pathologies are correlated to an imbalance (dysbiosis) of the bacterial microbiota, an essential player in the preservation of skin homeostasis. However, it is strongly presumed that the effect of pollutants on the skin involves direct mechanisms of action but also an indirect mechanism linked to the alteration of the cutaneous microbiota by the pollutant. Consequently, it is relevant to address the effect of gaseous NO2 (gNO2) on the cutaneous microbiota. This thesis aims to assess the physiological, morphological and molecular impact of gNO2 on commensal bacterial strains of representative species of the cutaneous microbiota (Staphylococcus aureus, Staphylococcus epidermidis, Staphylococcus capitis, Pseudomonas fluorescens, Corynebacterium tuberculostearicum). Depending on the species, different responses to gNO2-generated nitrosative stress were thus highlighted as well as a higher tolerance to gNO2 for some of them. This work therefore suggests that gNO2 could contribute to the formation of a dysbiotic state of the cutaneous microbiota and participate in the pollutant indirect action on the skin
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Hu, Keng-ming, and 胡耿銘. "The properties of carbon paste electrode used for transdermal absorption studies of active ingredient in cosmetics." Thesis, 2008. http://ndltd.ncl.edu.tw/handle/92024301255374218156.
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碩士嘉南藥理科技大學
化妝品科技研究所
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The ultimate purpose of this research is to develop a on-line electrochemical analysis system used for in-situ transdermal absorption studied for cosmetics. The manufacturing and performance analysis of electrode which is the key component in electrochemical analysis are the main scope in this study. Compared to platinum electrode, the cost of materials used for fabricating carbon electrode is much lower. Therefore, this study is focused on the manufacturing process and performance analysis of carbon electrode. The effect of conductive carbon content on the activity of electrode was studied. Electrochemical Impedance Spectroscopy(EIS) was used to characterize the electrode. Cyclic Voltammetry(CV) was used to analysis the response of the electrode to K3[Fe(CN)6] and vitamin C and its derivatives which are the common active ingredient of in cosmetics. The effect of supporting electrolyte’s concentration on response current was also studied. The polarization resistance and capacity of the carbon electrode obtained from electrochemical impedance analysis show good reproducibility. The response of self-made carbon electrode to K3[Fe(CN)6] shows well redox behavior and the responses to ascorbic acid, magnesium ascorbyl phosphate and ascorbyl glucoside show competent linear relation to the concentration of the analyte in the range of 5.0x10-2~1.0x10-4 M with correlation coefficient higher than 0.9988. Furthermore, the response of carbon electrode to ascorbic acid has the highest sensitivity than it to ascorbyl glucoside and the response to magnesium ascorbyl phosphate got the lowest sensitivity among these three vitamin C related substances. In summary, the self-made carbon electrode in this study shows good stability and competent reproducible response to analyte. The applicable concentration range for active ingredient in cosmetics can be established by analyzing the linear relation and sensitivity of the response to the analyte. It is promising that there are great potential for the utilization of this electrode in the developing of on-line electrochemical in-situ transdermal absorption analysis system. The test and research result found the carbon electrode of manufacture, make use of the Electrochemical Impedance Spectroscopy method to get characteristic parameters, such as...etc, representability the carbon electrode of manufacture have fairly good and stability. And analysis result of Cyclic Voltammetry method have rather consistent and stability at different contained respondence of redox.As for analyze the often used active ingredient - vitamin C and its derivatives, we found concentrations of within the scope of, its respond of value of line relationship factor,all reaches 0.9988 above, simultaneously at vitamin C, vitamin C phosphoric acid magnesium and the vitamin C glucose between the vitamin C have the highest sensitivity,vitamin C glucose secondly, the vitamin C phosphoric acid magnesium lowest. Summary above result, this research of the carbon electrode have an equal, moreover analysis respondence of redox with fairly good reproducibility and stability,to utilize the electrode analyze sensitivity of samples and line relation of samples respond that we can build up a scope of detected with electrode application in the active ingredient,therefore applies this electrode establishment electrochemical the on-line and in-situ absorbed system through the skin that should have a good development potential.
Books on the topic "Cosmetic active ingredients"
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Kozlowski, Angela C. Biologically active ingredients: Demonstrating their mechanisms and proof of efficacy. Carol Stream, IL: Allured Pub Corp, 2009.
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Delivery systems for cosmetic active ingredients. Southborough, Mass: Drug and Market Development Publications, 1999.
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Cosmetically active ingredients: Recent advances. Carol Stream, Ill: Allured Books, 2011.
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Cosmeceuticals: Active Skin Treatment (C&t Ingredient Resource). Allured Publishing Corporation, 2005.
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Kristmundsdóttir, Thórdís, and Skúli Skúlason. "Lipids as Active Ingredients in Pharmaceuticals, Cosmetics and Health Foods." In Lipids and Essential Oils as Antimicrobial Agents, 151–77. Chichester, UK: John Wiley & Sons, Ltd, 2010. http://dx.doi.org/10.1002/9780470976623.ch7.
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Stiger-Pouvreau, Valérie, and Fabienne Guerard. "Bio-Inspired Molecules Extracted from Marine Macroalgae: A New Generation of Active Ingredients for Cosmetics and Human Health." In Blue Biotechnology, 709–46. Weinheim, Germany: Wiley-VCH Verlag GmbH & Co. KGaA, 2018. http://dx.doi.org/10.1002/9783527801718.ch22.
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Metcalfe, C., and T. Causer. "The Inside Story – The Science Behind Active Ingredients." In Discovering Cosmetic Science, 225–61. The Royal Society of Chemistry, 2020. http://dx.doi.org/10.1039/bk9781782624721-00225.
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This chapter covers a wide range of active ingredients and product types, demonstrating how specific ingredients work in your products and why they are used. The chapter takes a look both at ingredients that are widely used in products to deliver ‘everyday’ functions, such as antioxidants and preservatives, and at some of the industry's ‘special’ palette of active ingredients, such as peptides and vitamins.
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Jain, Saloni, Dr Pankaj Sharma, Harish Sharma, and Himanshi Bhalerao. "TRANSDERMAL DELIVERY OF HERBAL MEDICINE BY NANO-FIBROUS LOADED COSMETIC FACE MASK: A PROMISING APPROACH FOR DELIVERY OF DRUGS." In Futuristic Trends in Pharmacy & Nursing Volume 2 Book 24, 80–90. Iterative International Publishers, Selfypage Developers Pvt Ltd, 2023. http://dx.doi.org/10.58532/v2bs24ch8.
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To get beyond the drawbacks of conventional preparation, nano-fibres technology has been successfully used to create drug delivery systems. Its use has been expanded to numerous pharmaceutical disciplines, including injection preparation, oral preparation, and external preparation, and it has recently made an appearance in the field of cosmetics for use in the enhancement of attractiveness. The fact that nano-fibres may successfully boost the percutaneous penetration and significantly increase skin retention of active components in functional cosmetics accounts for the extensive influence of nano-fibres in the cosmetics sector. Nano-fibres, meantime, can successfully increase the water dispersion of insoluble active cosmetic compounds, improve the stability of efficacy components, and achieve the codelivery of several cosmetic active ingredients
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Wiechers, Johann W. "Optimizing Skin Delivery of Active Ingredients From Emulsions." In Delivery System Handbook for Personal Care and Cosmetic Products, 409–36. Elsevier, 2005. http://dx.doi.org/10.1016/b978-081551504-3.50025-0.
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Boruah, Tridip, Barsha Devi, Nibedita Gogoi, and Chiranjib Mili. "Algal and Microalgal Compounds in Cosmeceuticals." In Bioprospecting of Natural Sources for Cosmeceuticals, 144–71. Royal Society of Chemistry, 2024. http://dx.doi.org/10.1039/9781837672288-00144.
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A significant focus during the 21st century has been avoiding synthetic products and replacing them with suitable natural products in our daily life. Many substances used in these synthetic products are absorbed through the skin by the body, making them hazardous to the environment, as well as to the human body. The cosmetics industry is a huge market for the exploration of natural product-based organizations, since there is scope to improve almost all the manufacturing methodologies of cosmeceutical production. Algae are photosynthetic thallus-like organisms that possess a wide range of bioactive compounds that contribute to products such as pharmaceuticals, cosmetics, and nutritious feeds, which are valuable for human health and wellness. They are wealthy resources of vital nutrients, such as amino acids, proteins, vitamins, pigments, minerals, and long-chain polyunsaturated fatty acids. These ingredients are employed in cosmetic formulations either as excipients, additives or active substances. Apart from that, these algae are very fast growing and there is always a sustainable approach to use it in the cosmetic industry as an alternative to many synthetic ingredients. This chapter will deal with algal-based cosmeceuticals in terms of their secondary metabolites, bioactive compounds and pharmacological potential, and the market products obtained from them.
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Iftekhar, Huma. "Mesoporous Materials for Cosmetics." In Materials Research Foundations, 441–69. Materials Research Forum LLC, 2025. https://doi.org/10.21741/9781644903452-17.
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Mesoporous materials are emerging as new carriers in cosmetic formulations due to their unique structural properties including high surface area, tunable pore size and controlled release capacity. These materials provide active ingredients such as antioxidants, vitamins and UV filters that are more stable, effective and skin penetrating. Their biocompatibility and ability to protect delicate materials from damage make them ideal for use in anti-aging, skin whitening and sun protection products Despite the many benefits, there are never complications so just like production scalability and regulatory approval. This chapter explores the synthesis, applications, and future potential of mesoporous materials in cosmetics.
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Nunes, Maria Antónia, Francisca Rodrigues, and Maria Beatriz P. P. Oliveira. "Grape Processing By-Products as Active Ingredients for Cosmetic Proposes." In Handbook of Grape Processing By-Products, 267–92. Elsevier, 2017. http://dx.doi.org/10.1016/b978-0-12-809870-7.00011-9.
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Orlans, F. Barbara, Tom L. Beauchamp, Rebecca Dresser, David B. Morton, and John P. Gluck. "Beauty Without the Beast." In The Human Use Of Animals, 121–36. Oxford University PressNew York, NY, 1998. http://dx.doi.org/10.1093/oso/9780195119077.003.0006.
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Abstract We have produced a range of products which are ‘cruelty-free,’ non-toxic and environmentally safe with ingredients which are not animal tested Homecare Technology Ltd Organic Product Company skin care products are based on traditional herbal remedies that have been tried and tested on people not animals’ The production of new cosmetics is now considered by many persons to be unjustified if animals suffer pain, distress, or death during premarketing safety testing. When the campaign against cosmetic testing reached significant dimensions in the 1970s and 1980s, animal tests commonly caused blindness, pain, and death to rabbits, rats, and other animals. Many improvements have been made to alleviate these problems, but animal welfare groups as well as some cosmetics manufacturers remain active in pressing for a ban on testing the safety of cosmetics that involves animals.
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Yosipovitch, Gil. "Active Ingredients in Cosmetic PreparationsCONTENTSOverviewNaturally occurring substances extracted from animal tissuesPlant extractsAromatic oilsVitaminsCommon foodstuffsSome additional comments." In Series in Cosmetic and Laser Therapy, 131–42. Informa Healthcare, 2009. http://dx.doi.org/10.3109/9781616310004.016.
Full textConference papers on the topic "Cosmetic active ingredients"
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Tsyganova, Irina Vladimirovna, Tatyana Vasilievna Ilyina, and Victoria Alexandrovna Ermolaeva. "DEVELOPMENT OF TECHNOLOGY FOR THE PRODUCTION OF COSMETIC BALM BASED ON NATURAL CARROT ROOT EXTRACT." In Themed collection of papers from Foreign International Scientific Conference «Trends in the development of science and Global challenges» Ьу НNRI «National development» in cooperation with AFP. December 2022. Crossref, 2023. http://dx.doi.org/10.37539/man5.2022.17.57.002.
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Today, cosmetic products containing natural ingredients and a minimum amount of excipients are in demand. Therefore, the development of new technologies and formulations of natural-based cosmetics is a promising area of scientific research in the production of extracts from plant materials, the search for optimal combinations of bases and active ingredients.
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Ruth, Feliadewi, Sjaikhurrizal El-Muttaqien, Gita Syahputra, Riyona Desvy Pratiwi, Nunik Gustini, Widji Soeratri, and A’liyatur Rosyidah. "The role of nanocarriers in delivering active cosmetic ingredients for skin care applications: A review." In THE 10TH INTERNATIONAL BASIC SCIENCE INTERNATIONAL CONFERENCE (BASIC) 2022. AIP Publishing, 2023. http://dx.doi.org/10.1063/5.0166497.
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Bedina Zavec, Apolonija. "Extracellular Vesicles for Cosmetic Applications." In Socratic Lectures 8. University of Lubljana Press, 2023. http://dx.doi.org/10.55295/psl.2023.ii16.
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Extracellular vesicles (EVs) are nanosized membrane vesicles that carry membrane and cargo molecules inherited from their parental cells. Excellent delivery capacity, biological origin, and nanosized dimensions support the great potential of EVs as medical and cosmetic active ingredients. Many studies have already reported improved skin conditions by using EVs for skin rejuvenation, scar removal, and anti-pigmentation treatments. In this review, EVs from mesenchymal stem cells, platelets, skin microbiota, and microalgae will be considered. The most promising results come from mesenchymal stem cell (MSC) derived EVs that have impressive antiaging and wound-healing effects on the skin, but their use for medical or cosmetic purposes is not yet allowed in Europe and the United States. Autologous platelet- and extracellular vesicle-rich plasma (PVRP) is well tolerated and capable of rejuvenating the face; intradermal injections and topical applications are currently being considered in clinical and cosmetic dermatology. Symbiotic microorganisms of the human skin have many beneficial effects on the skin, but the presence of bacteria in cosmetic products is restricted; therefore, the preparation of EVs from skin-beneficial microbes is particularly relevant, and there are already many cosmetic products containing lysates from different probiotics on the market. Microalgae can produce many valuable bioactive compounds, antioxidants such as carotenoids are particularly interesting; therefore, microalgae are promising producers of EVs that could be used in cosmetic products. Keywords: Extracellular vesicles; Skin health; Microbiota; Mesenchymal stem cells; Micro-algae
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Stojaković, Jelena D., Zorana Z. Đuraš, Tatjana M. Đurkić, and Antonije E. Onjia. "OPTIMIZATION OF SOLID-PHASE EXTRACTION FOR TRACE ANALISYS OF ORGANIC UV FILTERS IN WATER." In IX Regional Conference Industrial Energy and Environmental Protection in the Countries of Southeast Europe, 325–31. Society of Thermal Engineers of Serbia,, 2024. http://dx.doi.org/10.46793/ieep24.325s.
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Organic UV filters are substances widely used as active ingredients in cosmetic products for protection against solar radiation. The frequent application of sunscreens containing multiple UV filters has led to their extensive release into the aquatic environment, posing adverse effects on aquatic organisms. There is a reason for concern about their presence in the environment due to their persistence and potential bioaccumulation in organisms, as well as their negative impact on the endocrine systems of humans and animals. Low concentrations of UV filters in natural waters make their detection challenging, thus requiring the selection of appropriate sample preparation techniques for analysis. This work aims to optimize solid-phase extraction for the analysis of selected UV filters in water. Organic UV filters commonly used as active ingredients in sunscreens were selected for analysis. High-performance liquid chromatography coupled with tandem mass spectrometry was used to identify and quantify the analytes. Five factors that are most significant for the efficiency of solid-phase extraction (sample volume and pH-value, salt concentration in the sample, eluent type and volume) were optimized. The optimized sample preparation technique enabled the examination of fiveselected UV filters with high extraction yields (75%–112%) and an enrichment factor of 150, allowing for trace-level analysis of these chemicals in water.
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Boka, V.-I., S. Athanasopoulou, E. Spanidi, E. Beletsiotis, G. Lagiopoulos, and K. Gardikis. "Bee Products in Cosmetic Industry: Propolis Extract a Potent “microbiome friendly” Active Ingredient." In GA – 70th Annual Meeting 2022. Georg Thieme Verlag KG, 2022. http://dx.doi.org/10.1055/s-0042-1759145.
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Letsiou, Sophia, Apostolos Beloukas, Efstathios Rallis, and Vasiliki Kefala. "In vitro skin models. Challenges and Future Steps." In 1st Conference of the Hellenic Scientific Society of Aesthetics. PHARMAKON-Press, 2024. http://dx.doi.org/10.61873/fcxv3865.
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The in vitro models have great potential in skin-related research as well as in testing for active ingredients in cosmetics, dermocosmetics and pharmaceuticals. Human skin behavior can be simulated in vitro using a variety of methods ranging from cell monolayer models to complicated organotypic and bioengineered three-dimensional models. Moreover, skin in vitro models offer an excellent alternative to animal testing in cosmetics and some of them are validated to be used as preclinical as-says. However, the in vitro simulation of the whole skin together with its appendages is still in its early stages. In this article we discuss a short evolution of skin models with its challenges and its future.
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Antunes-Ricardo, Marilena, Benjamín Escandón Ródriguez, Renatta Yanire González Escalera, Daniel Alejandro Rodríguez Ramirez, Laura Romero Robles, and Sayra Serrano-Sandoval. "Transferosomes as a delivery system for bioselenized protein hydrolysates as an active ingredient with cosmetic activity." In 22nd LACCEI International Multi-Conference for Engineering, Education and Technology (LACCEI 2024): “Sustainable Engineering for a Diverse, Equitable, and Inclusive Future at the Service of Education, Research, and Industry for a Society 5.0.”. Latin American and Caribbean Consortium of Engineering Institutions, 2024. http://dx.doi.org/10.18687/laccei2024.1.1.300.
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Stella, A., F. Bonnier, L. Miloudi, A. Tfayli, F. Yvergnaux, E. Munnier, and C. Tauber. "Minimum volume Constrained non-negative matrix factorization applied to the monitoring of active cosmetic ingredient into the skin in Raman imaging." In 10th International Conference on Pattern Recognition Systems (ICPRS-2019). Institution of Engineering and Technology, 2019. http://dx.doi.org/10.1049/cp.2019.0245.
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Berechet, Mariana Daniela, Demetra Simion, Rodica Roxana Constantinescu, Maria Stanca, and Cosmin Andrei Alexe. "Active Principles in Basil Essential Oil – Ocimum basilicum L. Cotton Linings with Antibacterial Properties." In The 9th International Conference on Advanced Materials and Systems. INCDTP - Leather and Footwear Research Institute (ICPI), Bucharest, Romania, 2022. http://dx.doi.org/10.24264/icams-2022.ii.3.
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Ocimum basilicum L. is an aromatic plant in the family Lamiaceae with bioactive properties used since ancient times in traditional medicine. The active ingredients of basil essential oil can be used in perfumes, pharmaceuticals, medicine, cosmetics or spices. In this study, the essential oil of basil was obtained by hydrodistillation in the Clevenger continuous extractor. It was characterized by GC-MS and 53 constituent compounds were identified. The majority compounds were highlighted: linalool, 64,569%, p-allyl anisol, 5,163%, Eucalyptol, 3,745%, α-Cadinene, 3,510%. Kovats indices were calculated and FT-IR analysis was performed to confirm the specific constituent compounds. The essential oil of basil was microbiologically analyzed against Escherichia coli (ATCC 10536) Gram-negative bacteria and against Staphylococcus aureus (ATCC 6538) Gram-positive bacteria by diffusometric working method. Antibacterial activity was determined by measuring the diameter of the inhibition zone around the samples. Samples of filter paper and cotton fabric were used to simulate shoe lining and bandages. Basil essential oil has resistance against the tested strains, observing the increase of the inhibition zone with the increase of the amount of essential oil used in treatments (20 μL, 30 μL, 50 μL). The results showed that Ocimum basilicum L. may be a good candidate as a plant-derived antibacterial agent for medical footwear, wound dressings and other medical applications.
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Konrade, Daiga, and Kriss Spalvins. "Extraction of bioactives from pumpkin by-products and determination of their antioxidant activity." In Research for Rural Development 2022 : annual 28th international scientific conference proceedings. Latvia University of Life Sciences and Technologies, 2022. http://dx.doi.org/10.22616/rrd.28.2022.016.
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Agro-industrial and food processing from pumpkins (Cucurbitaceae) produces a large number of by-products: bark, pomace, seeds still rich in bioactive compounds, especially carotenoids and green pigments (proto chlorophyll (a and b) and proto pheophytin (a and b)), which exhibit a broad spectrum of health-promoting effects and can be used as ingredients in functional food and cosmetics. For extraction of bioactive compounds from dried pumpkin by-products different methods were used: supercritical CO2, Soxhlet extraction with n- hexane, ethanol. Vegetable oils (rapeseed, coconut, grapeseed and olive oil) were used as green solvent alternatives to conventional organic solvents for carotenoid extraction. Detection and analyses of chlorophylls and carotenoids was done with hexane/acetone, cyclohexane, ethanol as solvents. The aim of this study was to use pumpkin by-products for extraction of high-value bioactive compounds with different methods, to determine antioxidant´s content and profile – carotenoids (ß-carotene, lutein, lycopene, zeaxanthin), pigments (chlorophylls a, chlorophylls b) with different solvents and to find out what solvent can be used for detection of pigments and carotenoids; to determine antiradical scavenging activity of biologically active compounds in extracts from pumpkin by-products (peel and hulled seeds).