Academic literature on the topic 'Cosolvent Mixtures'

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Journal articles on the topic "Cosolvent Mixtures"

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Puentes-Lozada, Vanesa, Diego Ivan Caviedes-Rubio, Cristian Rincón-Guio, et al. "Thermodynamic Study of the Solubility of Triclocarban in Polyethylene Glycol 200 + Water Cosolvent Mixtures at Different Temperatures." Molecules 30, no. 12 (2025): 2631. https://doi.org/10.3390/molecules30122631.

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Background: Solubility is a fundamental physicochemical property in pharmaceutical, chemical and environmental industrial processes. Regarding Triclocarban (TCC), a broad-spectrum antimicrobial, solubility is particularly challenging due to its low aqueous solubility and hydrophobic nature; these challenges can be addressed by some effective techniques such as cosolvency, which allows one to increase the solubility of drugs by several orders of magnitude. This study aims to thermodynamically evaluate the solubility of TCC in cosolvent mixtures of PEG 200 + water at different temperatures. Meth
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Ortiz, Claudia Patricia, Rossember Edén Cardenas-Torres, Fleming Martínez, and Daniel Ricardo Delgado. "Solubility of Sulfamethazine in the Binary Mixture of Acetonitrile + Methanol from 278.15 to 318.15 K: Measurement, Dissolution Thermodynamics, Preferential Solvation, and Correlation." Molecules 26, no. 24 (2021): 7588. http://dx.doi.org/10.3390/molecules26247588.

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Solubility of sulfamethazine (SMT) in acetonitrile (MeCN) + methanol (MeOH) cosolvents was determined at nine temperatures between 278.15 and 318.15 K. From the solubility data expressed in molar fraction, the thermodynamic functions of solution, transfer and mixing were calculated using the Gibbs and van ’t Hoff equations; on the other hand, the solubility data were modeled according to the Wilson models and NRTL. The solubility of SMT is thermo-dependent and is influenced by the solubility parameter of the cosolvent mixtures. In this case, the maximum solubility was achieved in the cosolvent
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Jouyban, Abolghasem. "Review of the cosolvency models for predicting solubility of drugs in water-cosolvent mixtures." Journal of Pharmacy & Pharmaceutical Sciences 11, no. 1 (2008): 32. http://dx.doi.org/10.18433/j3pp4k.

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The cosolvency models presented from 1960 to 2007 were reviewed and their accuracies for correlating and/or predicting the solubility of drugs in water-cosolvent mixtures were discussed. The cosolvency models could be divided into theoretical, semi-empirical and empirical models, the first group of models provide basic information from the solution, while the last group of models are good suitable for solubility correlation studies. The simplest cosolvency model, i.e. the log-linear model of Yalkowsky, provides an estimate of drug solubility in water-cosolvent mixtures using aqueous solubility
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Zheng, Yan-Zhen, Hong Chen, Yu Zhou, Deng Geng, Hong-Yan He, and Li-Ming Wu. "The structure and hydrogen-bond properties of N-alkyl-N-methyl-pyrrolidinium bis(trifluoromethylsulfonyl)imide and DMSO mixtures." Physical Chemistry Chemical Physics 22, no. 48 (2020): 28021–31. http://dx.doi.org/10.1039/d0cp03640d.

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Mixing ionic liquids (ILs) with cosolvents can extend the practical applications of ILs and overcome the drawbacks of neat ILs. Studies on the structure and hydrogen-bond interaction properties of IL–cosolvent mixtures is essential for chemical applications.
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Tinjaca, Dario A., Maria M. Muñoz, Fleming Martinez, Abolghasem Jouyban, and William E. Acree Jr. "Apparent Specific Volumes of Sucrose in Different Aqueous Cosolvent Mixtures at 298.2 K." Pharmaceutical Sciences 24, no. 4 (2018): 324–31. http://dx.doi.org/10.15171/ps.2018.46.

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Background: Sucrose is the most widely used sweetener in foods and pharmaceuticals. Apparent specific volumes of this excipient in aqueous cosolvent mixtures are not available. Thus, the main objective of this research was to determine this property by measuring the density of several solutions of sucrose in {cosolvent + water} mixtures at 298.2 K. Methods: Sucrose dissolutions were prepared gravimetrically and a thermostatically controlled digital oscillatory method was used to measure the dissolutions density. Results: From density values of sucrose dissolutions and cosolvent mixtures the ap
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Trujillo-Trujillo, Carlos Francisco, Fredy Angarita-Reina, Mauricio Herrera, et al. "Thermodynamic Analysis of the Solubility of Sulfadiazine in (Acetonitrile 1-Propanol) Cosolvent Mixtures from 278.15 K to 318.15 K." Liquids 3, no. 1 (2022): 7–18. http://dx.doi.org/10.3390/liquids3010002.

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Drug solubility is one of the most significant physicochemical properties as it is related to drug design, formulation, quantification, recrystallization, and other processes, so understanding it is crucial for the pharmaceutical industry. In this context, this research presents the thermodynamic analysis of the solubility of sulfadiazine (SD) in cosolvent mixtures {acetonitrile + 1-propanol} at 9 temperatures (278.15 K–318.15 K), which is a widely used drug in veterinary therapy, and two solvents of high relevance in the pharmaceutical industry, respectively. The solubility of SD, in cosolven
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Martínez, Fleming, María Ángeles Peña, and Abolghasem Jouyban. "Dissolution Thermodynamics and Preferential Solvation of Phenothiazine in Some Aqueous Cosolvent Systems." Liquids 4, no. 2 (2024): 443–55. http://dx.doi.org/10.3390/liquids4020024.

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Published equilibrium mole fraction solubilities of phenothiazine in ethanol, propylene glycol and water as mono-solvents at several temperatures were investigated to find standard apparent thermodynamic quantities of dissolution mixing and solvation based on the van’t Hoff and Gibbs equations. Further, by processing the reported mole fraction solubility values of phenothiazine in some aqueous cosolvent mixtures at T/K = 298.2, the inverse Kirkwood–Buff integrals treatment demonstrated preferential hydration of phenothiazine in water-rich mixtures and preferential solvation of this agent by co
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Caviedes-Rubio, Diego Ivan, Claudia Patricia Ortiz, Fleming Martinez, and Daniel Ricardo Delgado. "Thermodynamic Assessment of Triclocarban Dissolution Process in N-Methyl-2-pyrrolidone + Water Cosolvent Mixtures." Molecules 28, no. 20 (2023): 7216. http://dx.doi.org/10.3390/molecules28207216.

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Solubility is one of the most important physicochemical properties due to its involvement in physiological (bioavailability), industrial (design) and environmental (biotoxicity) processes, and in this regard, cosolvency is one of the best strategies to increase the solubility of poorly soluble drugs in aqueous systems. Thus, the aim of this research is to thermodynamically evaluate the dissolution process of triclocarban (TCC) in cosolvent mixtures of {N-methyl-2-pyrrolidone (NMP) + water (W)} at seven temperatures (288.15, 293.15, 298.15, 303.15, 308.15, 313.15 and 318.15 K). Solubility is de
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Chalikian, Tigran V., and Soyoung Lee. "Solvation in Solvent-Cosolvent Mixtures." Biophysical Journal 96, no. 3 (2009): 602a. http://dx.doi.org/10.1016/j.bpj.2008.12.3180.

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Masegosa, R. M., I. Hernández-Fuentes, I. Fernández de Piérola, and A. Horta. "Polystyrene fluorescence in cosolvent mixtures." Polymer 28, no. 2 (1987): 231–35. http://dx.doi.org/10.1016/0032-3861(87)90409-5.

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Dissertations / Theses on the topic "Cosolvent Mixtures"

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Morris, Kenneth Robert 1951. "THE SOLUBILITY OF HYDROPHOBIC POLLUTANTS IN WATER-COSOLVENT MIXTURES." Thesis, The University of Arizona, 1986. http://hdl.handle.net/10150/276659.

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Zêzere, Bruno Miguel Martins. "Diffusivities of bioactive compounds in supercritical mixtures and expanded solvents." Master's thesis, Universidade de Aveiro, 2017. http://hdl.handle.net/10773/22524.

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Mestrado em Engenharia Química<br>Nas últimas décadas, os fluidos supercríticos têm ganho maior destaque no âmbito dos paradigmas de biorrefinaria e sustentabilidade de processos químicos, surgindo como alternativa verde a muitos solventes orgânicos. Em particular, sendo o dióxido de carbono supercrítico (SC-CO2) o solvente preferido, são necessários valores experimentais e modelos preditivos de difusividades de solutos tanto em SC-CO2 puro como modificado com cossolvente. Esta tese surge como resposta à falta de dados e modelos nesta área, tendo como principal objetivo a medição e posterior m
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Vyalov, Ivan. "Molecular dynamics simulation of dissolution of cellulose in supercritical fluids and mixtures of cosolvents/supercritical fluids." Thesis, Lille 1, 2011. http://www.theses.fr/2011LIL10178/document.

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La cellulose est le polymère naturel le plus abondant. Cependant son utilisation est limitée par sa faible dissolution due à des liaisons hydrogènes intra et inter moléculaires. Jusqu’à aujourd’hui des solvants toxiques sont utilisés dans les procédés de dissolutions de la cellulose. Par conséquent de nouveaux solvants pour la dissolution de la cellulose ont été intensivement étudiés comme solutions de rechange de ces procédés polluants. Une des solutions est d’utiliser la technologie des fluides supercritiques utilisant le dioxyde de carbone. Malheureusement, la cellulose reste insoluble dans
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Vyalov, Ivan. "Molecular dynamics simulation of dissolution of cellulose in supercritical fluids and mixtures of cosolvents/supercritical fluids." Electronic Thesis or Diss., Lille 1, 2011. http://www.theses.fr/2011LIL10178.

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La cellulose est le polymère naturel le plus abondant. Cependant son utilisation est limitée par sa faible dissolution due à des liaisons hydrogènes intra et inter moléculaires. Jusqu’à aujourd’hui des solvants toxiques sont utilisés dans les procédés de dissolutions de la cellulose. Par conséquent de nouveaux solvants pour la dissolution de la cellulose ont été intensivement étudiés comme solutions de rechange de ces procédés polluants. Une des solutions est d’utiliser la technologie des fluides supercritiques utilisant le dioxyde de carbone. Malheureusement, la cellulose reste insoluble dans
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Lee, Maeng Eun [Verfasser]. "Atomistic simulations of cosolvent-water mixtures : force field development and application to cosolvent effects on nonpolar solubility and hydrophobic interactions / Maeng Eun Lee." 2006. http://d-nb.info/982382456/34.

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LePree, Jason Michael. "Solubility of naphthalene in binary aqueous organic cosolvent mixtures an investigation of the phenomenological model /." 1993. http://catalog.hathitrust.org/api/volumes/oclc/32678209.html.

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Yu, Wen-Yueh, and 游文月. "Cosolvent Effects on the Spontaneous Formation of Vesicles from 1:1 Cationic and Anionic Surfactant Mixtures." Thesis, 2004. http://ndltd.ncl.edu.tw/handle/8u6ex6.

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碩士<br>國立成功大學<br>化學工程學系碩博士班<br>92<br>This work aims to provide a practical vesicle-boosting method by means of cosolvent addition in water and propose a theoretical explanation which can delineate the general trend of cosolvent effects and elucidate the possible role of cosolvent in the formation of catanionic vesicles. Effects of four homologous cosolvents (methanol, ethanol, 1-propanol, and 1-butanol) on the spontaneous formation of vesicles from eight 1:1 anionic-cationic mixed surfactant systems sodium alkyl sulfates�{alkyltrimethylammonium bromides (CnSO4Na�{CmN(CH3)3Br; n = 12, 14; m = 8,
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Book chapters on the topic "Cosolvent Mixtures"

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Annable, Michael D., James W. Jawitz, Randall K. Sillan, and P. Suresh Rao. "In-Situ Solubilization by Cosolvent and Surfactant—Cosolvent Mixtures." In ACS Symposium Series. American Chemical Society, 1999. http://dx.doi.org/10.1021/bk-1999-0725.ch007.

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Minnick, David L., Raul A. Flores, and Aaron M. Scurto. "Viscosity and Rheology of Ionic Liquid Mixtures Containing Cellulose and Cosolvents for Advanced Processing." In ACS Symposium Series. American Chemical Society, 2017. http://dx.doi.org/10.1021/bk-2017-1250.ch008.

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Hassan, A., K. L. Levien, and J. J. Morrell. "Phase Behavior of Binary and Ternary Mixtures of Wood Preservatives in Supercritical CO2with Cosolvents." In Innovations in Supercritical Fluids. American Chemical Society, 1995. http://dx.doi.org/10.1021/bk-1995-0608.ch027.

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Kiefer, Johannes. "Vibrational Spectroscopy for Studying Hydrogen Bonding in Imidazolium Ionic Liquids and their Mixtures with Cosolvents." In Hydrogen Bonding and Transfer in the Excited State. John Wiley & Sons, Ltd, 2010. http://dx.doi.org/10.1002/9780470669143.ch16.

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Hammou, Hassan O., Isabel M. Plaza del Pino, and Jose M. Sanchez-Ruiz. "Preferential hydration changes upon protein unfolding in water-cosolvent mixtures." In Progress in Biotechnology. Elsevier, 1998. http://dx.doi.org/10.1016/s0921-0423(98)80037-3.

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Abildskov, J., and J. P. O'Connell. "Prediction of solubilities of complex medium-sized chemicals. Solutes in pure solvents, mixed solvents and cosolvent mixtures." In Computer Aided Chemical Engineering. Elsevier, 2005. http://dx.doi.org/10.1016/s1570-7946(05)80158-0.

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Watanabe, Masaru, Masayoshi Wagatsuma, Keisuke Suzuki, et al. "Resource Upgrading in Advanced Supercritical Fluid (Supercritical Fluid with Catalyst and Cosolvent): Liquid Fuels from Biomass in Sub and Supercritical Water and Carbohydrate Up-Conversion in Ionic Liquid and Supercritical Fluids Mixtures." In Advanced Supercritical Fluids Technologies. IntechOpen, 2020. http://dx.doi.org/10.5772/intechopen.89793.

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Doraiswamy, L. K. "Bioorganic Synthesis Engineering." In Organic Synthesis Engineering. Oxford University Press, 2001. http://dx.doi.org/10.1093/oso/9780195096897.003.0029.

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Biological processes, from the simplest to the most complex, can broadly be classified as those caused by the catalytic action of living entities known as microorganisms or microbes, and those promoted and catalyzed by “lifeless substances” produced by microorganisms, known as enzymes. The two together are often referred to as biocatalysts. The microbial kingdom of living entities consists of all living things with a very simple biological organization. Both microbes and enzymes can be used to promote or selectively achieve a wide range of chemical transformations. Indeed, biocatalysts occupy
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Chernyak, Yury, and Florence Henon. "Coatings from Liquid and Supercritical Carbon Dioxide." In Green Chemistry Using Liquid and Supercritical Carbon Dioxide. Oxford University Press, 2004. http://dx.doi.org/10.1093/oso/9780195154832.003.0018.

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This chapter describes several aspects of the use of carbon dioxide as a solvent or cosolvent in coating applications. The primary impetus for using carbon dioxide for this purpose has been the alleviation of volatile emissions and liquid solvent wastes. However, the special physical properties of liquid and supercritical carbon dioxide may offer some processing advantages over conventional organic or aqueous solvents. Liquid carbon dioxide is quite compressible, and a reduction in temperature results not only in a reduction in the operating pressure, but also in a significant increase in the
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"put capacity and does not require premixing; it is fairly inexpensive and suitable for continuous operation. Major drawbacks to this equipment are its lack of availability, the need for special heating and cooling control systems, no available laboratory model, and the need for many trial-and-error runs in order to scale-up to production. 8. Static Mixers A true low-shear and low-energy requirement device for emulsifying immiscible liq-uid mixtures is the static mixer. Sometimes called a pipeline mixer, this device is ac-tually a series of specially designed baffles in a cylindrical pipe as shown in Fig. 42. These simple devices are used extensively for the preparation of unstable emulsions for liquid-liquid extraction purposes. Droplet sizes, obtainable using static mixers, have been studied extensively and vary with viscosity, interfacial tension, pressure drop, and static mixer design [45]. Size distributions obtainable range from 1000-100 |am. Hence, al-though there are very few emulsions stable in this region, the static mixer has seen application as an in-line premixer in continuous processes or in recirculation loops to batch-processing equipment. F. Nonmechanical Disperse Processing Recently a new processing technique became available for the production of stable and uniform liposomes. It uses the physico-chemical properties of the supercritical liquids rather than the mechanical forces of the pumps. One such a process technology is pre-sented in this section. 1. Critical Fluids Liposome Process Near-critical or supercritical fluid solvents with or without polar cosolvents (SuperFluids™) (Aphios, Corp., Woburn, MA) for the formation of uniform and stable liposomes having high encapsulation efficiencies has been used [46-48]. Supercritical or near-critical fluids as shown by the pressure-temperature diagram in Fig. 43, are gases such as carbon dioxide and propane that have been processed under ambient conditions. When compressed at conditions above their critical temperature and pres-sure, these substances become fluids with liquidlike density and the ability to dissolve other materials, and gaslike properties of low viscosity and high diffusivity. The gas-eous characteristics increase mass transfer rates, thereby significantly reducing process-ing time. Small added amounts of miscible polar cosolvents, such as alcohol, can be used to adjust polarity and to maximize the selectivity and capacity of the solvent. Fig. 42 Static mixer. (From Ref. 44.)." In Pharmaceutical Dosage Forms. CRC Press, 1998. http://dx.doi.org/10.1201/9781420000955-56.

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