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1

Kala, Chandra, Syed Salman Ali, and Sudhir Chaudhary. "COMPARATIVE PHARMACOGNOSTICAL EVALUATION OF COSTUS SPECIOSUS (WILD GINGER) AND ZINGIBER OFFICINALE (GINGER) RHIZOME." International Journal of Current Pharmaceutical Research 8, no. 4 (2016): 19. http://dx.doi.org/10.22159/ijcpr.2016v8i4.15270.

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Objective: Costus speciosus Koen. (Ginger) is an Indian ornamental plant, belonging to family Costaceae. The present research work deals with the establishment of standardization parameter regarding comparative pharmacognostic study between Costus speciosus and Zingiber officinale rhizome.Methods: Macroscopic and microscopic evaluation, physicochemical parameters like ash values, moisture content, extractive value, fluorescence analysis and the preliminary phytochemical investigation was done.Results: The Macroscopic difference was found as an absence of odor and taste in Costus speciosus and
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2

Verma, Yogita, and Shubha Diwan. "HPLC analysis of costunolide from Costus speciosus (Koen ex. Retz.) Sm. plants of Chhattisgarh region." Research Journal of Chemistry and Environment 28, no. 10 (2024): 88–92. http://dx.doi.org/10.25303/2810rjce088092.

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Costus speciosus (Koen ex. Retz.) Sm. is a medicinal plant known for its therapeutic properties, prominently attributed to its bioactive constituents like costunolide, diosgenin, eremanthin etc. This study presents a detailed investigation on the quantitative analysis of costunolide in Costus speciosus plants collected from different geographical regions of Chhattisgarh, employing High-Performance Liquid Chromatography (HPLC) technique. The research methodology involved the crude extraction of metabolites from the rhizome using methanol as solvent followed by HPLC analysis. The results reveale
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3

Saraswathi Ilango, Saikumar P, Sembulingam K, and SaiKarthik Jayakumar. "Antistressor effect of Costus speciosus on noise induced immunological changes in rats." International Journal of Research in Pharmaceutical Sciences 11, no. 3 (2020): 2973–78. http://dx.doi.org/10.26452/ijrps.v11i3.2388.

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Costus speciosus is being widely used in Indian folk medicine for treating various disorders. Environmental noise pollution is supposed to be an important factor for many health problems and it causes immune abnormalities. In the present study immune-regulating potential of Costus speciosus extract was evaluated during acute and subacute noise stress conditions. Adult Wistar albino rats were exposed to acute noise stress and subacute noise stress and then the effect of ethanolic Costus speciosus rhizome extract on immunological parameters such as phagocytic index, avidity index, neutrophil adh
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4

Marzook, Ebtisam A., Fawzy A. Marzook, and Ahmed E. Abd El Moneim. "Radioprotective and anti-diabetic effects of Costus speciosus and carnosine." Tropical Journal of Pharmaceutical Research 19, no. 1 (2020): 121–27. http://dx.doi.org/10.4314/tjpr.v19i1.19.

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Purpose: To evaluate the possible radioprotective effect of Costus speciosus and carnosine as natural antioxidants in order to control the hyperglycemia developed in male albino rats exposed to acute oxidative stress induced by gamma radiation.
 Methods: Twenty-eight adult male albino rats were divided into four groups. The first group was taken as a control group, while the three other groups were exposed to Ɣ irradiation at a single 7.5 Gy dose. Furthermore, the rats in the second and third groups were i.p. injected with Costus speciosus root powder and carnosine, respectively. On the 3
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5

Delarosa, Athoya, Ryan Proxy Hendrawan, and Eli Halimah. "Screening of Costus speciosus and Determination of Antioxidant Potential Using DPPH Method: A Review." European Journal of Medicinal Plants 34, no. 7 (2023): 17–28. http://dx.doi.org/10.9734/ejmp/2023/v34i71146.

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Medicinal plants are garnering widespread interest in scientific circles due to their consistent pharmacological activities, which make them beneficial in the treatment of a variety of ailments. Costus speciosus, commonly known as crepe ginger, is an herbaceous plant native to Mexico that belongs to the family Costaceae (zingiberaceae). Creep Ginger is known to have many medicinal effects, such as antioxidant, anti-inflammatory, and potential antidiabetic activities. The aim of this review was to investigate the phytochemical compounds and potential antioxidant activity in Costus speciosus. Th
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6

Da Luz, Petterson Baptista, Severino De Paiva Sobrinho, and Armando Reis Tavares. "Plant spacing and phosphate fertilization on costus." Ornamental Horticulture 24, no. 3 (2018): 225–30. http://dx.doi.org/10.14295/oh.v24i3.1211.

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The Cheilocostus speciosus is a species with ornamental potential, but the lack of scientific and technical information for fertilization and management of cut flowers production, turns essential to research in this area on floriculture. The aim of this work was to evaluate the production of C. speciosus fertilized with different levels of phosphate and plant spacing. Four treatments were used in a factorial scheme, with two plant spacing (1.20 x 0.80 m and 1.20 x 1.60 m) and two levels of phosphate fertilization (35 and 70 g per plant). The variables analyzed were number of vegetative stems,
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7

AL-Douri, Asmaa S., Khawla Mohemad Salih, and Omer M. Sultan. "The effect of Indian Qost (Costus speciosus) on the healing of oral incision in rabbits." Romanian Journal of Stomatology 70, no. 2 (2025): 158–65. https://doi.org/10.37897/rjs.2025.2.3.

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Background. Costus speciosus is a medicinal and ornamental plant widely used in several indigenous systems of medicine to treat various ailments. Its bioactive components are believed to have antimicrobial properties and may accelerate wound healing. Methods. One concentration of Costus speciosus extract (8 g/100 ml distilled water) was used as a mouth rinse. Oral wounds were induced in all rabbits, which were then divided into two groups of 8 rabbits each. The first group was treated with the Costus speciosus mouth rinse three times daily, while the second group served as the control. After t
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8

AL-YAHYA, ABDULRAHMAN A. I., MOHAMMED ASAD, ABDULMONIEM SADABY, and KHALID ELFAKKI IBRAHIM. "Short Communication: Augmentation of cardioprotective effect of captopril by Costus speciosus against isoproterenol induced myocardial toxicity in rats." Nusantara Bioscience 9, no. 3 (2017): 295–99. http://dx.doi.org/10.13057/nusbiosci/n090309.

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Al-Yahya AAI, Asad M, Sadaby A, Ibrahim KE. 2017. Short Communication: Augmentation of cardioprotective effect of captopril by Costus speciosus against isoproterenol induced myocardial toxicity in rats. Nusantara Bioscience 9: 295-299. This study determined the pharmacodynamic interaction of captopril, a known cardioprotective effect with methanolic extract of Costus speciosus rhizomes (Costaceae) that is known for its powerful antioxidant action during isoproterenol induced cardiac toxicity in rats. A methanolic extract of the rhizomes was prepared by maceration. Rats were administered the me
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9

Susanti, Hari, Subagus Wahyuono, Ratna Asmah Susidarti, and Ika Puspita Sari. "PENETAPAN KADAR DIOSGENIN DALAM EKSTRAK AIR Costus speciosus SECARA HPLC." Majalah Obat Tradisional 22, no. 1 (2017): 1. http://dx.doi.org/10.22146/tradmedj.24171.

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Costus speciosus has been reported to have biological activity among antidiabetic, antihyperlipidemia, antioxidants. One of the chemical constituents that is responsible for some of the biological activity is diosgenin. This study aimed to determine diosgenin content of Costus speciosus water extract (CS). Water extract of CS was obtained with infundation method. The extract was dried using freeze dryer. The assay of diosgenin was performed by HPLC method. HPLC system used: LiChrospher® 100 RP-18 endcapped (5 µm) column length 25cm, colimn id 4 mm as stationary phase, acetonitrile-water (9: 1
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10

Agrawal, Sandip, Nitin Kochar, and Anil Chandewar. "Review on Costus speciosus a Medicinal Plant." Research Journal of Pharmacy and Technology 11, no. 4 (2018): 1697. http://dx.doi.org/10.5958/0974-360x.2018.00316.5.

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11

Al-Attas, Ahmed A. M., Nagwa S. El-Shaer, Gamal A. Mohamed, Sabrin R. M. Ibrahim, and Ahmed Esmat. "Anti-inflammatory sesquiterpenes from Costus speciosus rhizomes." Journal of Ethnopharmacology 176 (December 2015): 365–74. http://dx.doi.org/10.1016/j.jep.2015.11.026.

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12

Susanti, Hari, Subagus Wahyuono, Ratna Asmah Susidarti, and Ika Puspita Sari. "Antihypercholesterol activity of costus speciosus water extract." Thai Journal of Pharmaceutical Sciences 42, no. 2 (2018): 66–68. http://dx.doi.org/10.56808/3027-7922.2383.

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13

Khan, M. Ferose, and A. Ramu. "Spectral characterization of bioactive compounds from Costus pictus and Costus speciosus." International Journal of ChemTech Research 11, no. 9 (2018): 353–63. http://dx.doi.org/10.20902/ijctr.2018.110941.

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14

G M, RADHA DEVI. "EXTRACTION, Extraction, Isolation, Identification and Estimation of Diosgenin by TLC Profiling and UHPLC-LC-SRM Analysis in Three Costus Species." Journal of Drug Delivery and Therapeutics 14, no. 11 (2024): 120–27. http://dx.doi.org/10.22270/jddt.v14i11.6878.

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Medicinal plants are utilized for treating many ailments, since ancient times due to their tremendous therapeutic properties. The plant derivatives are used as a raw material for the synthesis of drugs either as a natural or artificial synthetic drug. Costaceae family members are known to possess many medicinal properties few of them are mainly consumed to reduce the blood glucose level and treat many disorders. The sapogenin contained in the rhizome of three Costus species was extracted, identified, and characterized. Young rhizomes were harvested surface sterilized, hydrolyzed; extracted thr
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15

Castro, Carlos Eduardo Ferreira de, Silvia Rocha Moreira, Cecília Ribeiro de Castro, et al. "Avaliação de espécies de Costaceae para uso ornamental." Revista Brasileira de Horticultura Ornamental 17, no. 1 (2011): 63. http://dx.doi.org/10.14295/rbho.v17i1.719.

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<p>Este trabalho teve como objetivos mensurar e avaliar características morfológicas e agronômicas de 12 espécies da família Costaceae do banco de germoplasma de Zingiberales ornamentais do Instituto Agronômico (IAC), visando à indicação de espécies de costáceas para uso ornamental, considerando as categorias para uso como flor de corte, hastes cortadas, plantas de vaso e paisagismo. Em condições de campo, foram avaliadas dez plantas de cada espécie, com idade de um ano. Para a caracterização morfológica, foram utilizados 28 caracteres e avaliou-se a longevidade pós-colheita das inflores
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16

El-Far, AliHafez, HazemM Shaheen, AbdelWahab Alsenosy, YasserS El-Sayed, SoadK Al Jaouni, and ShakerA Mousa. "Costus speciosus: Traditional uses, phytochemistry, and therapeutic potentials." Pharmacognosy Reviews 12, no. 23 (2018): 120. http://dx.doi.org/10.4103/phrev.phrev_29_17.

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17

Singh, Pradeep, Garima Mishra, RL Khosa, Shruti Srivastava, KK Jha, and Sourabh Srivastava. "Anthelmintic activity of aerial parts of Costus speciosus." International Journal of Green Pharmacy 5, no. 4 (2011): 325. http://dx.doi.org/10.4103/0973-8258.94356.

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18

Akhila, Anand, and Madan M. Gupta. "Biosynthesis and Translocation of Diosgenin in Costus speciosus." Journal of Plant Physiology 130, no. 2-3 (1987): 285–90. http://dx.doi.org/10.1016/s0176-1617(87)80233-x.

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19

Vijayalakshmi, M. A., and N. C. Sarada. "Screening of Costus speciosus extracts for antioxidant activity." Fitoterapia 79, no. 3 (2008): 197–98. http://dx.doi.org/10.1016/j.fitote.2007.11.014.

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20

Almeida, M. R., and S. M. Almeida. "A new Variety of Costus Speciosus (Retz.) Sm." Journal of the Bombay Natural History Society 96 (June 12, 1999): 355–56. https://doi.org/10.5281/zenodo.13412710.

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Almeida, M. R., and S. M. Almeida. "A new Variety of Costus Speciosus (Retz.) Sm." Journal of the Bombay Natural History Society 96 (June 7, 1999): 355–56. https://doi.org/10.5281/zenodo.13412710.

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22

Almeida, M. R., and S. M. Almeida. "A new Variety of Costus Speciosus (Retz.) Sm." Journal of the Bombay Natural History Society 96 (June 19, 1999): 355–56. https://doi.org/10.5281/zenodo.13412710.

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23

Almeida, M. R., and S. M. Almeida. "A new Variety of Costus Speciosus (Retz.) Sm." Journal of the Bombay Natural History Society 96 (July 3, 1999): 355–56. https://doi.org/10.5281/zenodo.13412710.

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24

Almeida, M. R., and S. M. Almeida. "A new Variety of Costus Speciosus (Retz.) Sm." Journal of the Bombay Natural History Society 96 (July 10, 1999): 355–56. https://doi.org/10.5281/zenodo.13412710.

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25

Almeida, M. R., and S. M. Almeida. "A new Variety of Costus Speciosus (Retz.) Sm." Journal of the Bombay Natural History Society 96 (July 17, 1999): 355–56. https://doi.org/10.5281/zenodo.13412710.

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26

Rukaya, Benazir Evita, Syuhada Syuhada, and Fajar Wahyu. "Studi Toksisitas Infusa Rimpang Pacing (Costus speciosus) dengan Metode Brine Shrimp Lethality Test (BSLT)." Journal Borneo 4, no. 3 (2025): 81–89. https://doi.org/10.57174/j.born.v4i3.155.

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Costus speciosus atau Pacing, merupakan tanaman herbal yang telah lama digunakan dalam pengobatan tradisional di berbagai negara Asia. Tanaman ini dilaporkan memiliki aktivitas biologis seperti antidiabetes, antiinflamasi, dan antikanker. Namun, informasi mengenai toksisitasnya masih terbatas. Penelitian ini bertujuan untuk mengetahui toksisitas infusa rimpang Costus speciosus menggunakan metode Brine Shrimp Lethality Test (BSLT). Metode ini memanfaatkan larva Artemia salina Leach sebagai organisme model untuk menilai potensi toksisitas. Rimpang pacing diketahui mengandung senyawa bioaktif sep
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27

R., Ghana Shyam* Ananda V. D. Visagaperumal Vineeth Chandy. "A REVIEW ON PHYTOCHEMICAL CONSTITUENTS AND MEDICINAL VALUES OF "Cheilocostus Speciosus"." International Journal in Pharmaceutical Sciences 2, no. 6 (2024): 389–95. https://doi.org/10.5281/zenodo.11517707.

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<em>Cheilocostus Speciosus</em> is a plant in the family Asteraceae It is widespread to Southeast Asia and adjacent regions, ranging from India to China to Queensland. It is particularly prevalent on Indonesia's Greater Sunda Islands. Puerto Rico, Mauritius, Reunion, Fiji, Hawaii, Costa Rica, Belize, Melanesia, Micronesia, and the West Indies are also said to have naturalised. This review includes the Plant profile, major constituents, Chemical test, and the pharmacological activities of <em>Cheilocostus Speciosus</em>. The main constituents of the plant were diosgenin, curcumin, and curcumino
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Siriwardhene, Malitha Aravinda, Sriaandhal Sabalingam, and Anil Goonetilleke. "Antidiabetic activity of methanol extract and fractions of Costus speciosus leaves in normal and alloxan induced diabetic rats." Journal of Drug Delivery and Therapeutics 13, no. 5 (2023): 5–12. http://dx.doi.org/10.22270/jddt.v13i5.6045.

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Introduction: Costus speciosus is a common plant used for the treatment of diabetes mellitus and various other ailments in traditional medicine in Sri Lanka. The present study was conducted to investigate the hypoglycemic effect of the leaves of C. speciosus in both normal and alloxan induced male Wistar diabetic rat models. Methods: A methanolic extract of the leaves was produced and used for the preliminary phytochemicals screening. Methanol extract was further partitioned with different solvents (n-hexane, chloroform, ethyl acetate and n-butanol) according to their polarity. Male Wistar rat
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Saraswathi Ilango, Saikumar P, Sembulingam Kandhaswamy, and SaiKarthik Jayakumar. "Neuroprotective potential of Costus speciosus on neurotransmitters levels in noise stress condition in rats." International Journal of Research in Pharmaceutical Sciences 11, no. 4 (2020): 5768–71. http://dx.doi.org/10.26452/ijrps.v11i4.3223.

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Exposure to overwhelming stress could lead to development of mental disorders and worsening of existing ones. The impact produced by exposure to stress might be affected by the seriousness of the stressor, the time amid which it is connected (acute vs. chronic). In traditional practice of medicine, C. speciosus extract exhibits antistress action so we aimed to test whether this extract plays a vital role in maintaining the brain's chemical transmitters levels during acute noise stress conditions. The levels of Dopamine (DA), Norepinephrine (NE) and Serotonin (5HT) were analysed by reverse phas
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Bakhshwin, Duaa, Khadija Abdul Jalil Faddladdeen, Soad Shaker Ali, Samar Mohammed Alsaggaf та Nasra Naeim Ayuob. "Nanoparticles of Costus speciosus Ameliorate Diabetes-Induced Structural Changes in Rat Prostate through Mediating the Pro-Inflammatory Cytokines IL 6, IL1β and TNF-α". Molecules 27, № 3 (2022): 1027. http://dx.doi.org/10.3390/molecules27031027.

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Diabetes mellitus is a common global health problem. Among the complications that are frequently associated with DM are the alternation of sexual function and fertility, especially in young men. This study aimed to assess the efficacy of nanoparticles of Costus speciosus (C. speciosus) in preserving the prostatic structure of diabetic rats and to explore the mechanism behind this effect. A model of DM was induced in male albino rats by a single intraperitoneally injection of streptozotocin (STZ, 60 mg/kg body weight). Five groups (n = 10 each) of rats were included in this study: the control,
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Mitra, Prasenjit, Tanaya Ghosh, and Prasanta Kumar Mitra. "Isolation of Anti Solar Compound from Costus Speciosus Leaves." Scholars Academic Journal of Pharmacy 09, no. 01 (2020): 18–22. http://dx.doi.org/10.36347/sajp.2020.v09i01.005.

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32

Chakraborty, Debpratim, Nisha Lama Yolmo, and Nisha Lama Yolmo. "COSTUS SPECIOSUS AND ITS ANTIPSORIATIC ARTHRITIS ACTIVITY: A REVIEW." Asian Journal of Pharmaceutical and Clinical Research 12, no. 1 (2019): 30. http://dx.doi.org/10.22159/ajpcr.2018.v12i1.20430.

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Objective: Psoriatic arthritis is an autoimmune disease. The marketed drugs cannot totally cure the disease state as well as they have severe side effects and for that reason researcher and scientists are going for traditional medicines. Costus speciosus is the plant of choice for its several positive activities against psoriatic arthritis.Methods: Wistar albino healthy rat was taken for 0.1 ml of Freund adjuvant-induced anti-arthritic and anti-inflammatory test, and diclofenac sodium (15 mg/kg) was taken as standard drug. The paw volume was measured at different time 1st, 7th, 14th, and 21st
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Chakraborty, Debpratim, Nisha Lama Yolmo, and Nisha Lama Yolmo. "COSTUS SPECIOSUS AND ITS ANTIPSORIATIC ARTHRITIS ACTIVITY: A REVIEW." Asian Journal of Pharmaceutical and Clinical Research 12, no. 1 (2019): 30. http://dx.doi.org/10.22159/ajpcr.2019.v12i1.20430.

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Objective: Psoriatic arthritis is an autoimmune disease. The marketed drugs cannot totally cure the disease state as well as they have severe side effects and for that reason researcher and scientists are going for traditional medicines. Costus speciosus is the plant of choice for its several positive activities against psoriatic arthritis.Methods: Wistar albino healthy rat was taken for 0.1 ml of Freund adjuvant-induced anti-arthritic and anti-inflammatory test, and diclofenac sodium (15 mg/kg) was taken as standard drug. The paw volume was measured at different time 1st, 7th, 14th, and 21st
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Dnyaneshwar, Sonwane* Grishma Bawankar* Aachal Dudhpachare* Vishakha Chindhalore Bharti Machhirke Mayur Deshmukh S. G. Pathan. "A Review on Antimicrobial Property of Costus Speciosus (Keukand)." International Journal of Pharmaceutical Sciences 3, no. 1 (2025): 2207–13. https://doi.org/10.5281/zenodo.14744439.

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Keukand, a traditional medicinal plant, has been used for centuries in various cultures. Its bioactive compounds exhibit promising pharmacological activities.&nbsp;&nbsp; Rhizomes are given in pneumonia, rheumatism, dropsy, urinary diseases, jaundice while leaves are given in mental disorders. Bruised leaves are applied in fever; decoction of stem is used in fever and dysentery. Various other activities are also reported like anti-inflammatory, antiarthritic effect and antifungal activities.&nbsp; The plant is also&nbsp; used&nbsp; in&nbsp; gout&nbsp; rheumatism and bronchial&nbsp; asthma.&nbs
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Verma, Yogita, Jyotsna Dewangan, and Shubha Diwan. "Costus speciosus (Koen. ex. Retz.) Sm.: An updated Review on Therapeutic Potential and Conservation through Biotechnology." NewBioWorld 6, no. 1 (2024): 42–53. https://doi.org/10.52228/nbw-jaab.2024-6-1-6.

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India is one of the mega biodiversity countries in the world with massive forests as a hub for indigenous medicinal plant resources. Costus speciosus (Koen. ex. Retz.) Sm. is a valuable medicinal herb of tropical and subtropical India, known for its anti-diabetic property. It is used for the treatment of various disorders in traditional systems of medicine such as Ayurveda and Siddha. Pharmaceutical industries are fundamentally dependent on the conventional supply of medicinal and aromatic plant-based substances. Overexploitation of plants for the manufacturing of herbal pharmaceuticals, and i
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Huda Ali Hadi and Rasheed H. Hasan. "Effect of plant extracts of Salvia officinalis L. and Costus speciosus L. in growth of some bacteria species isolated from urinary tract infections in Samarra city." Tikrit Journal of Pure Science 25, no. 1 (2020): 47–51. http://dx.doi.org/10.25130/tjps.v25i1.212.

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The present study aimed to investigate the inhibitory effect of alcoholic extract (methanol - ethanol) and flavonoids by diffusion methods of wells of Salvia officinalis L. and Costus speciosus L. plants on Escherichia . coli and Proteus spp. isolated from patients with urinary tract infection Samarra city, the samples were collected during the period from 15/7/2018 to 30/9/2018, It was found through the results that the extracts plant that used in this study showed various inhibitory effect against, The bacteria species study imitation , where on differ this effect by difference the concentra
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Khan, Abira, SM Mahbubur Rashid, and M. Aftab Uddin. "Phytochemical Analysis and In Vitro Antimicrobial Activity of Costus speciosus Extracts." Bangladesh Journal of Microbiology 39, no. 2 (2023): 46–52. http://dx.doi.org/10.3329/bjm.v39i2.66264.

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Costus speciosus (J. Koenig) Sm., commonly known as crepe ginger, is primarily used as an ornamental plant worldwide. The aim of this research was to study the phytoconstituents of locally collected C. speciosus plant samples and test their antimicrobial effect against selected bacterial strains. Phytochemical analysis showed the presence of alkaloids, flavonoids, steroids, phenolic compounds, tannins, glycosides, and cardiac glycosides in the extracts. The extracts displayed variable degrees of antibacterial activity against the microorganisms in a bioautography experiment based on thin-layer
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AlSaadi, Baiaan H., Shoaa H. AlHarbi, Sabrin R. M. Ibrahim, Amal A. El-Kholy, Dina S. El-Agamy, and Gamal A. Mohamed. "HEPATOPROTECTIVE ACTIVITY OF COSTUS SPECIOSUS (KOEN. EX. RETZ.) AGAINST PARACETAMOL-INDUCED LIVER INJURY IN MICE." African Journal of Traditional, Complementary and Alternative medicines 15, no. 2 (2018): 35. http://dx.doi.org/10.21010/ajtcamv15i2.5.

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Background: Liver diseases are a common cause of mortality and morbidity over the world. It is caused mainly by toxic chemicals and chemotherapeutic agents. Costus speciosus (Koen ex. Retz.) (Zingiberaceae) is widely employed in various traditional medicines for the prevention and treatment of different aliments. The purpose of this study is to assess the protective effect of C. speciosus rhizomes MeOH extract against the injury of the liver induced by paracetamol (PA) in mice.&#x0D; Material and Methods: The mice were pretreated for seven days with distilled H2O, silymarin 12 mg/kg or 100 and
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Chaudhary, Mridul Kant, Ankita Misra, Prabhat Kumar Srivastava, and Sharad Srivastava. "Influence of Seasonal Variation on Diosgenin Content in Costus speciosus (J. Koenig) Sm. Rhizome Quantified Through Validated RP-HPLC-PDA Method." Pharmacognosy Magazine 19, no. 1 (2023): 66–74. http://dx.doi.org/10.1177/09731296221137404.

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Background Costus speciosus (J. Koenig) Sm. (Syn. Cheilocostus speciosus) is an ethnic anti-diabetic plant, used for its high diosgenin content. Objectives This study aimed to evaluate the seasonal variation of diosgenin content in Costus speciosus rhizome, quantified through validated RP-HPLC method. Materials and Methods The rhizomes were collected in four different seasons, such as rainy (August), autumn (October), winter (February) and summer (May), from Lucknow, India. The HPLC method validation was done in terms of linearity, precision, repeatability, accuracy, sensitivity and robustness
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Karunaratne, Diyathi N., Samith B. Jayawardana, Harindu Rajapaksha, Yasas Sathyajith, and Dinesh R. Pandithavidana. "Comparative Computational Analysis of Antidiabetic Potential of Diosgenin, Costunolide and Eremanthin from Costus speciosus (Sri Lankan Thebu)." Asian Journal of Chemistry 37, no. 5 (2025): 1075–82. https://doi.org/10.14233/ajchem.2025.33519.

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Costus speciosus is a medicinal plant used in Eastern medicine (also known as Asian medicine) due to its phytochemical content, which has been shown to significantly lower blood sugar levels in diabetic patients. The primary objective of this study was to conduct a comparative analysis of the antidiabetic potential of diosgenin, costunolide and eremanthin from Costus speciosus, in comparison to the standard drug, acarbose. Molecular docking studies revealed that diosgenin exhibited the highest potential as a natural antidiabetic agent by inhibiting four diabetic-regulating enzymes with docking
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Tran, Thanh Men, Trong Tuan Nguyen, and Kim Yen Huynh. "Antioxidant Activity of Ethanolic Extracts of Artemisia Vulgaris, Pouzolzia zeylanica and Costus Speciosus." INTERNATIONAL JOURNAL OF AGRICULTURE AND BIOLOGICAL SCIENCES 5, July & Aug (2021): 01–07. https://doi.org/10.5281/zenodo.5515320.

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<em>This study aimed to evaluate the antioxidant and antibacterial activities of some plants collected in Kien Giang province, Vietnam. The antioxidant property was determined for their antioxidant activity by DPPH, ABTS●+, RP v&agrave; TAC methods in vitro. The results showed that the ethanolic extract of Artemisia vulgaris displayed in vitro antioxidant activities with its IC50 (half&nbsp;maximal&nbsp;inhibitory&nbsp;concentration) values of 734.323&nbsp;&micro;g/mL, 43.871&nbsp;&micro;g/mL, 185.32&nbsp;&micro;g/mL&nbsp;and 62.714&nbsp;&micro;g/mL, respectively. Antioxidant assay identified
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Hadi, Huda Ali, and Rasheed H. Hasan. "Effect of plant extracts of Salvia officinalis L. and Costus speciosus L. in growth of some bacteria species isolated from urinary tract infections in Samarra city." Tikrit Journal of Pure Science 25, no. 1 (2020): 47. http://dx.doi.org/10.25130/j.v25i1.933.

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The present study aimed to investigate the inhibitory effect of alcoholic extract (methanol - ethanol) and flavonoids by diffusion methods of wells of Salvia officinalis L. and Costus speciosus L. plants on Escherichia . coli and Proteus spp. isolated from patients with urinary tract infection Samarra city, the samples were collected during the period from 15/7/2018 to 30/9/2018, It was found through the results that the extracts plant that used in this study showed various inhibitory effect against, The bacteria species study imitation , where on differ this effect by difference the concentra
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Mitra, Prasenjit, Tanaya Ghosh, and Prasanta Kumar Mitra. "Anti Solar Activity of Costus Speciosus Leaves of Sikkim Himalayas." Scholars Academic Journal of Pharmacy 09, no. 01 (2020): 5–8. http://dx.doi.org/10.36347/sajp.2020.v09i01.002.

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PUNYARANI, Kshetrimayum, and Jitendra G. SHARMA. "Micropropagation of Costus speciosus (Koen.) Sm. Using Nodal Segment Culture." Notulae Scientia Biologicae 2, no. 1 (2010): 58–62. http://dx.doi.org/10.15835/nsb213552.

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Tyagi, B. R., and M. M. Gupta. "Ploidy status and diosgenin content in Costus speciosus (Koen.) Sm." CYTOLOGIA 52, no. 1 (1987): 41–46. http://dx.doi.org/10.1508/cytologia.52.41.

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Waisundara, V. Y., M. I. Watawana, and N. Jayawardena. "Costus speciosus and Coccinia grandis : Traditional medicinal remedies for diabetes." South African Journal of Botany 98 (May 2015): 1–5. http://dx.doi.org/10.1016/j.sajb.2015.01.012.

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Mohamad, Suriyati, Nur Najihah Ismail, Hasnah Osman, Habibah A Wahab, and Thaigarajan Parumasivam. "In Vitro Interactions of Costus speciosus (J. Koenig) Sm., Cymbopogon citratus (Dc. Ex Nees) Stapf. and Tabernaemontana coronaria (L.) Willd. with First-Line Anti-Tuberculosis Drugs Against Mycobacterium tuberculosis H37rv." Malaysian Journal of Pharmaceutical Sciences 19, no. 2 (2021): 171–78. http://dx.doi.org/10.21315/mjps2021.19.2.11.

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Global tuberculosis (TB) burden underscores the importance of developing new effective anti-TB drugs. This study was concerned with prospecting for potential anti-TB agents from Malaysian medicinal plants. In our previous study, we have reported that n-hexane fractions of Costus speciosus (C. speciosus) (J. Koening) Sm., Cymbopogon citratus (C. citratus ) (DC.) Stapf. and Tabernaemontana coronaria (T. coronaria) (Jacq.) posses promising anti-TB activity against Mycobacterium tuberculosis (M. tuberculosis) H37Rv with minimum inhibitory concentrations (MICs) of 200–100 µg/mL. This study aimed to
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Bawakid, Nahed O., Ahmed Abdel-Lateff, Fardous F. El-Senduny, and Walied M. Alarif. "Costus speciosus J Koenig (Costaceae) exerts anti-proliferative effect on breast cancer cells via induction of cell cycle arrest and inhibition of activity of metalloproteinase-2." Tropical Journal of Pharmaceutical Research 20, no. 7 (2022): 1365–72. http://dx.doi.org/10.4314/tjpr.v20i7.7.

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&#x0D; &#x0D; &#x0D; &#x0D; Purpose: To Investigate the antiproliferative effect of n-hexane-diethyl ether fraction of Costus speciosus (NP) on triple negative breast cancer (MDA-MB-231) cells, and the mechanism involved.&#x0D; Methods: Maceration with methanol (CH3OH) was used for extraction of Costus speciosus rhizomes. Chromatographic separation was used to obtain the non-polar fraction (NP) via elution with n-hexane:(C2H5)2O at a volume ratio of 9:1. The cytotoxic effect of NP was evaluated against two breast cancer cell lines i.e., triple negative (MDA-MB-231) and positive ER (MCF-7) empl
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Fatahalla, Ali Salim, Abubaker Diab Hussein, Kalil Hmedan Amna, Nor El-Din Dhidah Hanin, Elsidieg Baayo Remah, and Sarfaraj Hussain Md. "A study of Anti-bacterial, Anti-fungal Activities of Ethanolic and Aqueous Extracts of Costus speciosus." Pharmaceutical and Chemical Journal 6, no. 1 (2019): 11–18. https://doi.org/10.5281/zenodo.13926255.

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The <em>Costus speciosus </em>belonging to family Coastaceae, is a substantial medicinal and ornamental plant used traditionally to cure different diseases. <em>Aim: </em>The current studies were sought to determine the antimicrobial activities of ethanolic and aqueous extracts of <em>Costus speciosus </em>rhizome (CSEE and CSAE) against nine bacterial strains (<em>P. aeruginosa, S.&nbsp; epidermidis, S. pygenes, E. coli, K. pneumonia , S. Typhimurium, Proteus mirabillus, Bacillus species</em>)<em> </em>and three fungal strains (<em>Aspergillus fumigates, Penicillum species and Fusarium specie
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Huda Ali Hadi. "Studying the effect of plant extracts of Saliva officinalis L. and Costus speciosus L. on bacterial species causing urinary tract infection in Samarra." Tikrit Journal of Pure Science 26, no. 5 (2021): 16–21. http://dx.doi.org/10.25130/tjps.v26i5.171.

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The current study aimed at the possibility of benefiting from the plant extracts of the Costus speciosus and Salvia officinalis plants in the treatment of bacterial diseases through knowing the inhibitory effect of these extracts on the isolated bacterial species. The aqueous cold - hot and alcoholic extracts ethanol – methanol were tested with concentrations of 70,50,10 mg / ml and by the method of diffusion in pollen of Costus speciosus .L and Saliva officinalis L. on the bacterial genera Pseudomonas areuginosa, Klebsiella pneumonia, Enterobacter spp. that isolated from patients with urinary
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