Log in

Relevant bibliographies by topics / CoTC / Journal articles

To see the other types of publications on this topic, follow the link: CoTC.

Journal articles on the topic 'CoTC'

Author: Grafiati

Published: 4 June 2021

Last updated: 25 April 2022

Create a spot-on reference in APA, MLA, Chicago, Harvard, and other styles

Select a source type:

Consult the top 50 journal articles for your research on the topic 'CoTC.'

Next to every source in the list of references, there is an 'Add to bibliography' button. Press on it, and we will generate automatically the bibliographic reference to the chosen work in the citation style you need: APA, MLA, Harvard, Chicago, Vancouver, etc.

You can also download the full text of the academic publication as pdf and read online its abstract whenever available in the metadata.

Browse journal articles on a wide variety of disciplines and organise your bibliography correctly.

1

Imamura, Daisuke, Ritsuko Kuwana, Hiromu Takamatsu, and Kazuhito Watabe. "Localization of Proteins to Different Layers and Regions of Bacillus subtilis Spore Coats." Journal of Bacteriology 192, no. 2 (2009): 518–24. http://dx.doi.org/10.1128/jb.01103-09.

Full text

Abstract:

ABSTRACT Bacterial spores are encased in a multilayered proteinaceous shell known as the coat. In Bacillus subtilis, over 50 proteins are involved in spore coat assembly but the locations of these proteins in the spore coat are poorly understood. Here, we describe methods to estimate the positions of protein fusions to fluorescent proteins in the spore coat by using fluorescence microscopy. Our investigation suggested that CotD, CotF, CotT, GerQ, YaaH, YeeK, YmaG, YsnD, and YxeE are present in the inner coat and that CotA, CotB, CotC, and YtxO reside in the outer coat. In addition, CotZ and Cg

APA, Harvard, Vancouver, ISO, and other styles

2

Isticato, Rachele, Assunta Pelosi, Rita Zilhão, et al. "CotC-CotU Heterodimerization during Assembly of the Bacillus subtilis Spore Coat." Journal of Bacteriology 190, no. 4 (2007): 1267–75. http://dx.doi.org/10.1128/jb.01425-07.

Full text

Abstract:

ABSTRACT We report evidence that CotC and CotU, two previously identified components of the Bacillus subtilis spore coat, are produced concurrently in the mother cell chamber of the sporulating cell under the control of σK and GerE and immediately assembled around the forming spore. In the coat, the two proteins interact to form a coat component of 23 kDa. The CotU-CotC interaction was not detected in two heterologous hosts, suggesting that it occurs only in B. subtilis. Monomeric forms of both CotU and CotC failed to be assembled at the surface of the developing spore and accumulated in the m

APA, Harvard, Vancouver, ISO, and other styles

3

Cangiano, Giuseppina, Antonio Mazzone, Loredana Baccigalupi, et al. "Direct and Indirect Control of Late Sporulation Genes by GerR of Bacillus subtilis." Journal of Bacteriology 192, no. 13 (2010): 3406–13. http://dx.doi.org/10.1128/jb.00329-10.

Full text

Abstract:

ABSTRACT GerR is a sporulation-specific transcriptional factor of Bacillus subtilis that has been identified as a negative regulator of genes transcribed by σE-containing RNA polymerase and as a positive effector of the expression of three late sporulation genes. Here we confirmed that gerR transcription is dependent on σE-containing RNA polymerase but also observed that it requires the transcriptional regulator SpoIIID. The study of the role of GerR in regulating the expression of several late sporulation genes allowed us to observe that its effect is strongly positive on spoVIF, cotC, and co

APA, Harvard, Vancouver, ISO, and other styles

4

Isticato, Rachele, Assunta Pelosi, Maurilio De Felice, and Ezio Ricca. "CotE Binds to CotC and CotU and Mediates Their Interaction during Spore Coat Formation in Bacillus subtilis." Journal of Bacteriology 192, no. 4 (2009): 949–54. http://dx.doi.org/10.1128/jb.01408-09.

Full text

Abstract:

ABSTRACT CotE is a morphogenic protein that controls the assembly of the coat, the proteinaceous structure that surrounds and protects the spore of Bacillus subtilis. CotE has long been thought to interact with several outer coat components, but such interactions were hypothesized from genetic experiment results and have never been directly demonstrated. To study the interaction of CotE with other coat components, we focused our attention on CotC and CotU, two outer coat proteins known to be under CotE control and to form a heterodimer. We report here the results of pull-down experiments that

APA, Harvard, Vancouver, ISO, and other styles

5

Isticato, Rachele, Giovanni Esposito, Rita Zilhão, et al. "Assembly of Multiple CotC Forms into the Bacillus subtilis Spore Coat." Journal of Bacteriology 186, no. 4 (2004): 1129–35. http://dx.doi.org/10.1128/jb.186.4.1129-1135.2004.

Full text

Abstract:

ABSTRACT We report evidence that the CotC polypeptide, a previously identified component of the Bacillus subtilis spore coat, is assembled into at least four distinct forms. Two of these, having molecular masses of 12 and 21 kDa, appeared 8 h after the onset of sporulation and were probably assembled on the forming spore immediately after their synthesis, since no accumulation of either of them was detected in the mother cell compartment, where their synthesis occurs. The other two components, 12.5 and 30 kDa, were generated 2 h later and were probably the products of posttranslational modific

APA, Harvard, Vancouver, ISO, and other styles

6

Coste, Marine, Mikhail Tretiakov, Neil V. Shah, et al. "Does Percutaneous Achilles Tenotomy Yield Comparable Short-Term Outcomes to Combined Open Achilles Tenotomy with Posterior Capsulotomy in Pediatric Patients with Clubfoot?" Foot & Ankle Orthopaedics 4, no. 4 (2019): 2473011419S0015. http://dx.doi.org/10.1177/2473011419s00152.

Full text

Abstract:

Category: Hindfoot, Midfoot/Forefoot, Congenital Introduction/Purpose: As the most common musculoskeletal congenital anomaly, clubfoot (congenital talipes equinovarus) represents a commonly-encountered entity for pediatric orthopaedic and foot/ankle surgeons. As we have observed a shift towards more conservative, cost-conscious approaches to management, this study sought to compare short-term (30-day) perioperative and postoperative outcomes (complications and reoperations) in clubfoot patients who underwent either percutaneous Achilles tenotomy (PT) or combined open Achilles tenotomy with pos

APA, Harvard, Vancouver, ISO, and other styles

7

Zilhão, Rita, Mónica Serrano, Rachele Isticato, Ezio Ricca, Charles P. Moran, and Adriano O. Henriques. "Interactions among CotB, CotG, and CotH during Assembly of the Bacillus subtilis Spore Coat." Journal of Bacteriology 186, no. 4 (2004): 1110–19. http://dx.doi.org/10.1128/jb.186.4.1110-1119.2004.

Full text

Abstract:

ABSTRACT Spores formed by wild-type Bacillus subtilis are encased in a multilayered protein structure (called the coat) formed by the ordered assembly of over 30 polypeptides. One polypeptide (CotB) is a surface-exposed coat component that has been used as a vehicle for the display of heterologous antigens at the spore surface. The cotB gene was initially identified by reverse genetics as encoding an abundant coat component. cotB is predicted to code for a 43-kDa polypeptide, but the form that prevails in the spore coat has a molecular mass of about 66 kDa (herein designated CotB-66). Here we

APA, Harvard, Vancouver, ISO, and other styles

8

Negri, Alessandro, Wojciech Potocki, Adam Iwanicki, Michał Obuchowski, and Krzysztof Hinc. "Expression and display of Clostridium difficile protein FliD on the surface of Bacillus subtilis spores." Journal of Medical Microbiology 62, no. 9 (2013): 1379–85. http://dx.doi.org/10.1099/jmm.0.057372-0.

Full text

Abstract:

The endospores of Bacillus subtilis can serve as a tool for surface presentation of heterologous proteins. The unique properties of the spore protective layers make them perfect vehicles for orally administered vaccines. In this study, we successfully displayed a fragment of Clostridium difficile FliD protein on the surface of B. subtilis spores using the CotB, CotC, CotG and CotZ spore coat proteins. The presence of the fusion proteins in the spore coat was verified by Western blotting and immunofluorescence microscopy. The amount of recombinant proteins was assessed by a dot-blot technique.

APA, Harvard, Vancouver, ISO, and other styles

9

Powell-Coffman, J. A., and R. A. Firtel. "Characterization of a novel Dictyostelium discoideum prespore-specific gene, PspB, reveals conserved regulatory sequences." Development 120, no. 6 (1994): 1601–11. http://dx.doi.org/10.1242/dev.120.6.1601.

Full text

Abstract:

While Dictyostelium discoideum has been studied as a developmental system for decades, and many regulatory proteins have been cloned, the molecular mechanisms of cell-type-specific gene expression are poorly understood. In this paper we characterize a novel prespore gene, PspB, and undertake a comparative analysis of the regulatory regions in prespore-specific D. discoideum promoters. Sequence alignment of the PSPB gene product with other prespore-specific proteins identifies a conserved, repeated 12 amino acid cysteine-containing motif that may be involved in spore coat function or assembly.

APA, Harvard, Vancouver, ISO, and other styles

10

Giannakeas, Ilias N., Zahra Sharif Khodaei, and M. H. Ferri Aliabadi. "Structural Health Monitoring Cost Estimation of a Piezosensorized Aircraft Fuselage." Sensors 22, no. 5 (2022): 1771. http://dx.doi.org/10.3390/s22051771.

Full text

Abstract:

Guided waves-based SHM systems are of interest in the aeronautic sector due to their lightweight, long interrogation distances, and low power consumption. In this study, a bottom-up framework for the estimation of the initial investment cost (COTC) and the added weight (WAW) associated with the integration of a SHM system to an aircraft is presented. The framework provides a detailed breakdown of the activities and their costs for the sensorization of a structure using a fully wired approach or the adoption of the printed diagnostic film. Additionally, the framework considers the difference be

APA, Harvard, Vancouver, ISO, and other styles

11

Wang, Lijuan, John Perpich, Adam Driks, and Lee Kroos. "One Perturbation of the Mother Cell Gene Regulatory Network Suppresses the Effects of Another during Sporulation of Bacillus subtilis." Journal of Bacteriology 189, no. 23 (2007): 8467–73. http://dx.doi.org/10.1128/jb.01285-07.

Full text

Abstract:

ABSTRACT In the mother cell of sporulating Bacillus subtilis, a regulatory network functions to control gene expression. Four transcription factors act sequentially in the order σE, SpoIIID, σK, GerE. σE and σK direct RNA polymerase to transcribe different regulons. SpoIIID and GerE are DNA-binding proteins that activate or repress transcription of many genes. Several negative regulatory loops add complexity to the network. First, transcriptionally active σK RNA polymerase inhibits early sporulation gene expression, resulting in reduced accumulation of σE and SpoIIID late during sporulation. S

APA, Harvard, Vancouver, ISO, and other styles

12

Issa, Yousry M., Ahmed F. A. Youssef, and Mohamed A. Awady. "Colorimetric and Atomic Absorption Spectrometric Methods for the Determination of Hyoscine N-Butylbromide in Pharmaceutical Formulations Using Cobalt (II) and Chromium (III) Thiocyanate Complexes." Scientia Pharmaceutica 73, no. 4 (2005): 217–37. http://dx.doi.org/10.3797/scipharm.aut-05-16.

Full text

Abstract:

Two simple and sensitive colorimetric and atomic absorption spectrometric procedures have been established for determination of hyoscine N-butylbromide (Hyo.Br) in pure form and in pharmaceutical formulation. The methods are based on formation of an insoluble coloured ion-associate between the examined drug and tetrathiocyanatocobaltate (CoTC) or hexathiocyanatochromate (CrTC). The first method involves extraction of Hyo-CoTC and Hyo-CrTC ion-associates with methylene chloride and isobutyl alcohol, followed by measuring the absorbance at 630 and 557 nm, respectively. Optimization of the extrac

APA, Harvard, Vancouver, ISO, and other styles

13

Powell-Coffman, J. A., G. R. Schnitzler, and R. A. Firtel. "A GBF-binding site and a novel AT element define the minimal sequences sufficient to direct prespore-specific expression in Dictyostelium discoideum." Molecular and Cellular Biology 14, no. 9 (1994): 5840–49. http://dx.doi.org/10.1128/mcb.14.9.5840.

Full text

Abstract:

In order to better understand the molecular mechanisms of cellular differentiation in Dictyostelium discoideum, we have identified the minimum regulatory sequences of the prespore-specific gene SP60/cotC that are sufficient to confer cell-type-specific expression on a heterologous promoter. This region includes at least two essential cis-acting elements: a novel AT-rich element (or elements) and CAE3. The essential function of the AT element is confirmed through point mutations that decrease expression below the level of detection. CAE3 is one of three CA-rich elements (CAEs) required for the

APA, Harvard, Vancouver, ISO, and other styles

14

Powell-Coffman, J. A., G. R. Schnitzler, and R. A. Firtel. "A GBF-binding site and a novel AT element define the minimal sequences sufficient to direct prespore-specific expression in Dictyostelium discoideum." Molecular and Cellular Biology 14, no. 9 (1994): 5840–49. http://dx.doi.org/10.1128/mcb.14.9.5840-5849.1994.

Full text

Abstract:

In order to better understand the molecular mechanisms of cellular differentiation in Dictyostelium discoideum, we have identified the minimum regulatory sequences of the prespore-specific gene SP60/cotC that are sufficient to confer cell-type-specific expression on a heterologous promoter. This region includes at least two essential cis-acting elements: a novel AT-rich element (or elements) and CAE3. The essential function of the AT element is confirmed through point mutations that decrease expression below the level of detection. CAE3 is one of three CA-rich elements (CAEs) required for the

APA, Harvard, Vancouver, ISO, and other styles

15

Lin, Zhipeng, Hengchang Sun, Yan Ma, et al. "Evaluation of immune response to Bacillus subtilis spores expressing Clonorchis sinensis serpin3." Parasitology 147, no. 10 (2020): 1080–87. http://dx.doi.org/10.1017/s0031182020000797.

Full text

Abstract:

AbstractClonorchis sinensis (C. sinensis) is one of the most serious food-borne parasites, which can lead to liver fibrosis or cholangiocarcinoma. Effective measures for clonorchiasis prevention are still urgently needed. Bacillus subtilis (B. subtilis) is an effective antigen delivery platform for oral vaccines. Chonorchis sinensis serpin (CsSerpin) was proved to be potential vaccine candidates. In this study, CsSerpin3 was displayed on the surface of B. subtilis spore and recombinant spores were orally administrated to BALB/C mice. CsSerpin3-specific IgA levels in faecal, bile and intestinal

APA, Harvard, Vancouver, ISO, and other styles

16

Nguyen, Kim B., Anju Sreelatha, Eric S. Durrant, et al. "Phosphorylation of spore coat proteins by a family of atypical protein kinases." Proceedings of the National Academy of Sciences 113, no. 25 (2016): E3482—E3491. http://dx.doi.org/10.1073/pnas.1605917113.

Full text

Abstract:

The modification of proteins by phosphorylation occurs in all life forms and is catalyzed by a large superfamily of enzymes known as protein kinases. We recently discovered a family of secretory pathway kinases that phosphorylate extracellular proteins. One member, family with sequence similarity 20C (Fam20C), is the physiological Golgi casein kinase. While examining distantly related protein sequences, we observed low levels of identity between the spore coat protein H (CotH), and the Fam20C-related secretory pathway kinases. CotH is a component of the spore in many bacterial and eukaryotic s

APA, Harvard, Vancouver, ISO, and other styles

17

Crater, Dinene L., and Charles P. Moran. "Two Regions of GerE Required for Promoter Activation in Bacillus subtilis." Journal of Bacteriology 184, no. 1 (2002): 241–49. http://dx.doi.org/10.1128/jb.184.1.241-249.2002.

Full text

Abstract:

ABSTRACT GerE from Bacillus subtilis is the smallest member of the LuxR-FixJ family of transcription activators. Its 74-amino-acid sequence is similar over its entire length to the DNA binding domain of this protein family, including a putative helix-turn-helix (HTH) motif. In this report, we sought to define regions of GerE involved in promoter activation. We examined the effects of single alanine substitutions at 19 positions that were predicted by the crystal structure of GerE to be located on its surface. A single substitution of alanine for the phenylalanine at position 6 of GerE (F6A) re

APA, Harvard, Vancouver, ISO, and other styles

18

Sengupta, Nabonita, Syed Imteyaz Alam, Bhoj Kumar, et al. "Comparative Proteomic Analysis of Extracellular Proteins of Clostridium perfringens Type A and Type C Strains." Infection and Immunity 78, no. 9 (2010): 3957–68. http://dx.doi.org/10.1128/iai.00374-10.

Full text

Abstract:

ABSTRACTClostridium perfringensis a medically important clostridial pathogen and an etiological agent causing several diseases in humans and animals.C. perfringensand its toxins have been listed as potential biological and toxin warfare (BTW) agents; thus, efforts to develop strategies for detection and protection are warranted. Forty-eight extracellular proteins ofC. perfringenstype A and type C strains have been identified here using a 2-dimensional gel electrophoresis-mass spectrometry (2-DE-MS) technique. The SagA protein, the DnaK-type molecular chaperone hsp70, endo-beta-N-acetylglucosam

APA, Harvard, Vancouver, ISO, and other styles

19

Onukwugha, Ebere, Madhu Nagarajan, Husam Albarmawi, et al. "Treatment patterns among elderly follicular lymphoma patients diagnosed between 2000 and 2011: An analysis of linked SEER-Medicare data." Journal of Clinical Oncology 35, no. 15_suppl (2017): 7563. http://dx.doi.org/10.1200/jco.2017.35.15_suppl.7563.

Full text

Abstract:

7563 Background: There are multiple treatment regimens approved for the management of follicular lymphoma (FL). However, there is limited information available to describe the course of therapy (COT) that patients receive following FL diagnosis. Methods: Using the linked Surveillance, Epidemiology, and End Results (SEER) registry & Medicare claims dataset, we analyzed patients 66 years and older diagnosed with FL from 2000 to 2011. In order to characterize FL treatments, we identified first, second and subsequent-lines of therapy listed in the National Comprehensive Cancer Network guidelin

APA, Harvard, Vancouver, ISO, and other styles

20

Nomoto, Hiroki. "On indefinite subjects of pivot verbs in Malay." International Journal of Corpus Linguistics 14, no. 2 (2009): 221–54. http://dx.doi.org/10.1075/ijcl.14.2.04nom.

Full text

Abstract:

Indefinite subjects of so-called pivot verbs in Malay can appear on either side of the verb. This paper discusses the following two tendencies concerning their behaviour: (i) the longer the subject is, the more likely it is to occur after the verb; (ii) in adverbial clauses the preferred word order is VS rather than SV. Both of these points are supported by quantitative evidence from a corpus of front-page articles of the daily newspaper Utusan Malaysia. The paper also proposes an explanation for these tendencies by using the functional notion of ‘topic’ and the mechanism of competition. Speci

APA, Harvard, Vancouver, ISO, and other styles

21

Huntley, C. Frederick M., Harold B. Wood, and Bruce Ganem. "A new synthesis of the glyoxalase-I inhibitor COTC." Tetrahedron Letters 41, no. 13 (2000): 2031–34. http://dx.doi.org/10.1016/s0040-4039(00)00103-9.

Full text

APA, Harvard, Vancouver, ISO, and other styles

22

Baccigalupi, L. "GerE-independent expression of cotH leads to CotC accumulation in the mother cell compartment during Bacillus subtilis sporulation." Microbiology 150, no. 10 (2004): 3441–49. http://dx.doi.org/10.1099/mic.0.27356-0.

Full text

APA, Harvard, Vancouver, ISO, and other styles

23

Huntley, C. Frederick M., Harold B. Wood, and Bruce Ganem. "ChemInform Abstract: A New Synthesis of the Glyoxalase-I Inhibitor COTC." ChemInform 31, no. 25 (2010): no. http://dx.doi.org/10.1002/chin.200025200.

Full text

APA, Harvard, Vancouver, ISO, and other styles

24

Sun, Rui, Miao Zhang, Hui Chen, Yao Wei, and Degang Ning. "Germination-Arrest Bacillus subtilis Spores as An Oral Delivery Vehicle of Grass Carp Reovirus (GCRV) Vp7 Antigen Augment Protective Immunity in Grass Carp (Ctenopharyngodon idella)." Genes 11, no. 11 (2020): 1351. http://dx.doi.org/10.3390/genes11111351.

Full text

Abstract:

Oral vaccination is a practical method for the active immunization of farmed fish in the matter of animal welfare and handling costs. However, it always shows insufficient protective immunity, mainly due to antigen degradation in the gastrointestinal tract (GIT). Bacillus subtilis spores have been shown to be able to protect surface-display heterologous antigens against degradation. Neverthless, the spores can germinate in GIT, which causes loss of the antigens with spore coat disassembly. Here, we developed a novel surface display system using the B. subtilis spore coat proteins CotB and CotC

APA, Harvard, Vancouver, ISO, and other styles

25

Freitas, Geyson César de Oliveira, Gabriel Salathé Brandão Pereira, and Luiz Fernando Leite. "Prospecção tecnológica de processos crude oil to chemicals (COTC) e panorama de implantação mundial / Technological prospecting of crude oil to chemicals (COTC) processes and worldwide implementation overview." Brazilian Journal of Development 8, no. 2 (2022): 14526–44. http://dx.doi.org/10.34117/bjdv8n2-398.

Full text

APA, Harvard, Vancouver, ISO, and other styles

26

Crater, Dinene L., Kathryn H. Wade, Orna Resnekov, et al. "A mutation in GerE that affects cotC promoter activation in Bacillus subtilis." Biochimica et Biophysica Acta (BBA) - Gene Structure and Expression 1576, no. 1-2 (2002): 30–38. http://dx.doi.org/10.1016/s0167-4781(02)00294-4.

Full text

APA, Harvard, Vancouver, ISO, and other styles

27

Huntley, C. Frederick M., Diana S. Hamilton, Donald J. Creighton, and Bruce Ganem. "Reaction of COTC with Glutathione: Structure of the Putative Glyoxalase I Inhibitor." Organic Letters 2, no. 20 (2000): 3143–44. http://dx.doi.org/10.1021/ol006341z.

Full text

APA, Harvard, Vancouver, ISO, and other styles

28

Nojima, Takayuki, Martin Dienstbier, Shona Murphy, Nicholas J. Proudfoot, and Michael J. Dye. "Definition of RNA Polymerase II CoTC Terminator Elements in the Human Genome." Cell Reports 3, no. 4 (2013): 1080–92. http://dx.doi.org/10.1016/j.celrep.2013.03.012.

Full text

APA, Harvard, Vancouver, ISO, and other styles

29

Babu, D. Chanti, Ch Bhujanga Rao, K. Venkatesham, J. Jon Paul Selvam, and Y. Venkateswarlu. "Toward synthesis of carbasugars (+)-gabosine C, (+)-COTC, (+)-pericosine B, and (+)-pericosine C." Carbohydrate Research 388 (March 2014): 130–37. http://dx.doi.org/10.1016/j.carres.2013.08.008.

Full text

APA, Harvard, Vancouver, ISO, and other styles

30

Bauer, Tamara, Shawn Little, Axel G. Stöver, and Adam Driks. "Functional Regions of the Bacillus subtilis Spore Coat Morphogenetic Protein CotE." Journal of Bacteriology 181, no. 22 (1999): 7043–51. http://dx.doi.org/10.1128/jb.181.22.7043-7051.1999.

Full text

Abstract:

ABSTRACT The Bacillus subtilis spore is encased in a resilient, multilayered proteinaceous shell, called the coat, that protects it from the environment. A 181-amino-acid coat protein called CotE assembles into the coat early in spore formation and plays a morphogenetic role in the assembly of the coat’s outer layer. We have used a series of mutant alleles of cotE to identify regions involved in outer coat protein assembly. We found that the insertion of a 10-amino-acid epitope, between amino acids 178 and 179 of CotE, reduced or prevented the assembly of several spore coat proteins, including

APA, Harvard, Vancouver, ISO, and other styles

31

Wang, Lijuan, John Perpich, Adam Driks, and Lee Kroos. "Maintaining the Transcription Factor SpoIIID Level Late during Sporulation Causes Spore Defects in Bacillus subtilis." Journal of Bacteriology 189, no. 20 (2007): 7302–9. http://dx.doi.org/10.1128/jb.00839-07.

Full text

Abstract:

ABSTRACT During sporulation of Bacillus subtilis, four regulatory proteins act in the order σE, SpoIIID, σK, and GerE to temporally control gene expression in the mother cell. σE and σK work sequentially with core RNA polymerase to transcribe different sets of genes. SpoIIID and GerE are small, sequence-specific DNA-binding proteins that activate or repress transcription of many genes. Previous studies showed that transcriptionally active σK RNA polymerase inhibits early mother cell gene expression, reducing accumulation of SpoIIID late in sporulation. Here, the effects of perturbing the mothe

APA, Harvard, Vancouver, ISO, and other styles

32

Kamiya, Daisuke, Yuki Uchihata, Eiko Ichikawa, Kuniki Kato, and Kazuo Umezawa. "Reversal of anticancer drug resistance by COTC based on intracellular glutathione and glyoxalase I." Bioorganic & Medicinal Chemistry Letters 15, no. 4 (2005): 1111–14. http://dx.doi.org/10.1016/j.bmcl.2004.12.031.

Full text

APA, Harvard, Vancouver, ISO, and other styles

33

Chada, Venkata G. R., Erik A. Sanstad, Rong Wang, and Adam Driks. "Morphogenesis of Bacillus Spore Surfaces." Journal of Bacteriology 185, no. 21 (2003): 6255–61. http://dx.doi.org/10.1128/jb.185.21.6255-6261.2003.

Full text

Abstract:

ABSTRACT Spores produced by bacilli are encased in a proteinaceous multilayered coat and, in some species (including Bacillus anthracis), further surrounded by a glycoprotein-containing exosporium. To characterize bacillus spore surface morphology and to identify proteins that direct formation of coat surface features, we used atomic-force microscopy (AFM) to image the surfaces of wild-type and mutant spores of Bacillus subtilis, as well as the spore surfaces of Bacillus cereus 569 and the Sterne strain of Bacillus anthracis. This analysis revealed that the coat surfaces in these strains are p

APA, Harvard, Vancouver, ISO, and other styles

34

Mauriello, Emilia M. F., Le H. Duc, Rachele Isticato, et al. "Display of heterologous antigens on the Bacillus subtilis spore coat using CotC as a fusion partner." Vaccine 22, no. 9-10 (2004): 1177–87. http://dx.doi.org/10.1016/j.vaccine.2003.09.031.

Full text

APA, Harvard, Vancouver, ISO, and other styles

35

Shing, Tony K. M., and Ying Tang. "Enantiospecific synthesis of 2-crotonyloxy-(4R,5R,6R)-4,5,6-trihydroxycyclohex-2-enone (COTC) from quinic acid." Journal of the Chemical Society, Chemical Communications, no. 4 (1990): 312. http://dx.doi.org/10.1039/c39900000312.

Full text

APA, Harvard, Vancouver, ISO, and other styles

36

Arthurs, Claire L., Natasha S. Wind, Roger C. Whitehead, and Ian J. Stratford. "Analogues of 2-crotonyloxymethyl-(4R,5R,6R)-4,5,6-trihydroxycyclohex-2-enone (COTC) with anti-tumor properties." Bioorganic & Medicinal Chemistry Letters 17, no. 2 (2007): 553–57. http://dx.doi.org/10.1016/j.bmcl.2006.09.072.

Full text

APA, Harvard, Vancouver, ISO, and other styles

37

Alaya, Zeineb. "Sacral osteoid osteoma: a rare cause of back pain in childhood." Clinical Orthopaedics and Trauma Care 2, no. 1 (2020): 01–04. http://dx.doi.org/10.31579/cotc/2020/011.

Full text

Abstract:

Involvement of the sacrum is extremely rare, and it has also been reported that the diagnosis of osteoid osteoma in the sacrum can be delayed compared to other skeletal locations. We report the case of a six-year-old girl student who complained of chronic back pain for several months and with some relief with non-steroid anti-inflammatory drugs (NSAID). Further investigations, which included bone and CT scan, revealed the presence of an osteoid osteoma at the second sacral vertebra (S2 vertebra). The patient made an excellent recovery after surgical excision.

APA, Harvard, Vancouver, ISO, and other styles

38

Isticato, Rachele, Donatella Scotto Di Mase, Emilia M. F. Mauriello, Maurilio De Felice, and Ezio Ricca. "Amino terminal fusion of heterologous proteins to CotC increases display efficiencies in the Bacillus subtilis spore system." BioTechniques 42, no. 2 (2007): 151–56. http://dx.doi.org/10.2144/000112329.

Full text

APA, Harvard, Vancouver, ISO, and other styles

39

Adamiak, Mateusz, Malwina Suszynska, Ahmed Abdel-Latif, et al. "Novel Evidence That the Mannan-Binding Lectin (MBL) Pathway of Complement Activation Plays a Pivotal Role in Triggering Mobilization of Hematopoietic Stem/Progenitor Cells By Activation of Both the Complement and Coagulation Cascades." Blood 128, no. 22 (2016): 3371. http://dx.doi.org/10.1182/blood.v128.22.3371.3371.

Full text

Abstract:

Abstract Background . The complement cascade (ComC), which is part of the innate immune system, exerts several pleiotropic effects, and, as we have demonstrated, it is required for mobilization of hematopoietic stem/progenitor cells (HSPCs) during infection or tissue/organ injury as well as in response to administration of pharmacological mobilizing agents, such as G-CSF or AMD3100 (Blood 2004, 103, 2071-2078). The ComC is activated by three pathways: the classical, mannan-binding lectin (MBL), and alternative pathways. Activation of the ComC and generation of cleavage fragments of the fifth c

APA, Harvard, Vancouver, ISO, and other styles

40

Borkowska, Sylwia, Malwina Suszynska, Katarzyna Mierzejewska, et al. "Novel Evidence That Crosstalk Between Three Evolutionarily Ancient Proteolytic Enzyme Cascades (coagulation, fibrinolysis, and complement) Plays An Important Role In Mobilization Of Hematopoietic Stem/Progenitor Cells (HSPCs)." Blood 122, no. 21 (2013): 903. http://dx.doi.org/10.1182/blood.v122.21.903.903.

Full text

Abstract:

Abstract Background Hematopoietic stem/progenitor cells (HSPCs) residing in BM are released from their niches and circulate under steady-state conditions at detectable levels in the peripheral blood (PB), and their number increases in response to i) systemic or local inflammation, ii) strenuous exercise, iii) stress, iv) tissue/organ injury, and v) pharmacological agents. All these processes involve activation of the complement cascade (ComC), and while mice deficient in the complement protein C3, which is an upstream component of the ComC, are easy mobilizers (Blood 2004; 103:2071), mice defi

APA, Harvard, Vancouver, ISO, and other styles

41

Zilhão, R., G. Naclerio, A. O. Henriques, L. Baccigalupi, C. P. Moran, and E. Ricca. "Assembly Requirements and Role of CotH during Spore Coat Formation in Bacillus subtilis." Journal of Bacteriology 181, no. 8 (1999): 2631–33. http://dx.doi.org/10.1128/jb.181.8.2631-2633.1999.

Full text

Abstract:

ABSTRACT We report Western blot data showing that the 42.8-kDa product of the previously characterized cotH locus (8) is a structural component of the Bacillus subtilis spore coat. We show that the assembly of CotH requires both CotE and GerE. In agreement with these observations, the ultrastructural analysis of purified spores suggests that CotH is needed for proper formation of both inner and outer layers of the coat.

APA, Harvard, Vancouver, ISO, and other styles

42

Adamiak, Mateusz, Andrzej Ciechanowicz, Monika Cymer, Marta Skoda, and Mariusz Z. Ratajczak. "Nlrp3 Inflammasome Activation in Bone Marrow-Residing Innate Immunity Cells Governs Circadian Changes in the Number of Circulating Hematopoietic Stem/Progenitor Cells in Peripheral Blood." Blood 134, Supplement_1 (2019): 1033. http://dx.doi.org/10.1182/blood-2019-125853.

Full text

Abstract:

Background. The number of hematopoietic stem/progenitor cells (HSPCs) in peripheral blood (PB) undergoes a circadian oscillation, with the peak occurring in the early morning hours and the nadir at night, and, as nicely demonstrated, this peak has been attributed to the enhanced tonus of the vegetative nervous system in the early morning hours (Nature 2008, 452, 442-447). Moreover, our group has demonstrated that release of HSPCs from bone marrow (BM) into PB is regulated during stress- or pharmacology-induced mobilization by activation of three ancient serum proteolytic cascades, the compleme

APA, Harvard, Vancouver, ISO, and other styles

43

Valdez, A., G. Yepiz-Plascencia, E. Ricca, and J. Olmos. "First Litopenaeus vannamei WSSV 100% oral vaccination protection using CotC::Vp26 fusion protein displayed on Bacillus subtilis spores surface." Journal of Applied Microbiology 117, no. 2 (2014): 347–57. http://dx.doi.org/10.1111/jam.12550.

Full text

APA, Harvard, Vancouver, ISO, and other styles

44

Saggese, Anella, Rachele Isticato, Giuseppina Cangiano, Ezio Ricca, and Loredana Baccigalupi. "CotG-Like Modular Proteins Are Common among Spore-Forming Bacilli." Journal of Bacteriology 198, no. 10 (2016): 1513–20. http://dx.doi.org/10.1128/jb.00023-16.

Full text

Abstract:

ABSTRACTCotG is an abundant protein initially identified as an outer component of theBacillus subtilisspore coat. It has an unusual structure characterized by several repeats of positively charged amino acids that are probably the outcome of multiple rounds of gene elongation events in an ancestral minigene. CotG is not highly conserved, and its orthologues are present in only twoBacillusand twoGeobacillusspecies. InB. subtilis, CotG is the target of extensive phosphorylation by a still unidentified enzyme and has a role in the assembly of some outer coat proteins. We report now that most spor

APA, Harvard, Vancouver, ISO, and other styles

45

Borkowska, Sylwia, Malwina Suszynska, Janina Ratajczak, and Mariusz Z. Ratajczak. "Mice Deficient in the Fifth Complement Cascade Protein (C5) Do Not Display Circadian Changes in the Number of Circulating Hematopoietic Stem/Progenitor Cells (HSPCs) in Peripheral Blood (PB)—evidence for the Pivotal Role of the Distal Part of the Complement Cascade in Inducing the Circadian Release of HSPCs into PB." Blood 124, no. 21 (2014): 1122. http://dx.doi.org/10.1182/blood.v124.21.1122.1122.

Full text

Abstract:

Abstract Introduction. Activation of three ancient serum proteolytic cascades, the complement cascade (ComC), the coagulation cascade (CoaC), and the fibrynolytic cascade (FibC), is essential for release of hematopoietic stem progenitor cells (HSPCs) from bone marrow (BM) into peripheral blood (PB) during stress- or pharmacology-induced mobilization (Leukemia 2014,doi:10.1038/leu.2014.115). On the other hand, it has been convincingly demonstrated that there is a circadian oscillation in the number of circulating HSPCs in PB, with the peak occurring in the early morning hours and the nadir at n

APA, Harvard, Vancouver, ISO, and other styles

46

Huang, Wei, Jianfeng Huang, and Chengliang Yin. "Optimal Design and Control of a Two-Speed Planetary Gear Automatic Transmission for Electric Vehicle." Applied Sciences 10, no. 18 (2020): 6612. http://dx.doi.org/10.3390/app10186612.

Full text

Abstract:

Multispeed transmissions are helpful for improvement of the economy and drivability of electric vehicles (EVs). In this paper, we propose a two-speed transmission based on dual planetary gear mechanism, in which shifts are realized by torque transfer between two brakes located on ring gears. To synthesize the dynamic and economic performances of the vehicle, a multiobjective optimization problem is constructed for gear ratio optimization and Pareto-optimal solutions of gear ratio combinations are obtained by Nondominated sorting genetic algorithm-II (NSGA-II). In particular, the minimum electr

APA, Harvard, Vancouver, ISO, and other styles

47

Louis, S. A., G. B. Spiegelman, and G. Weeks. "Expression of an activated rasD gene changes cell fate decisions during Dictyostelium development." Molecular Biology of the Cell 8, no. 2 (1997): 303–12. http://dx.doi.org/10.1091/mbc.8.2.303.

Full text

Abstract:

It has been previously demonstrated that the expression of an activated rasD gene in wild-type Dictyostelium cells results in formation of aggregates with multitips, instead of the normal single tips, and a block in further development. In an attempt to better understand the role of activated RasD development, we examined cell-type-specific gene expression in a strain stably expressing high levels of RasD[G12T]. We found that the expression of prestalk cell-specific genes ecmA and tagB was markedly enhanced, whereas the expression of the prespore cell-specific gene cotC was reduced to very low

APA, Harvard, Vancouver, ISO, and other styles

48

Takahashi, Tamiko, Yoko Yamakoshi, Kazuya Okayama, Junko Yamada, Wei-Ying Ge, and Toru Koizumi. "High-Pressure Mediated Asymmetric Diels-Alder Reaction of Chiral Sulfinylacrylate Derivatives and Its Application to Chiral Synthesis of (-)-COTC and (-)-Gabosine C." HETEROCYCLES 56, no. 1-2 (2002): 209. http://dx.doi.org/10.3987/com-01-s(k)18.

Full text

APA, Harvard, Vancouver, ISO, and other styles

49

Arthurs, Claire L., Gareth A. Morris, Michela Piacenti, et al. "The synthesis of 2-oxyalkyl-cyclohex-2-enones, related to the bioactive natural products COTC and antheminone A, which possess anti-tumour properties." Tetrahedron 66, no. 46 (2010): 9049–60. http://dx.doi.org/10.1016/j.tet.2010.08.072.

Full text

APA, Harvard, Vancouver, ISO, and other styles

50

Gao, Yang, Xingchen Huo, Zhensheng Wang, et al. "Oral Administration of Bacillus subtilis Subunit Vaccine Significantly Enhances the Immune Protection of Grass Carp against GCRV-II Infection." Viruses 14, no. 1 (2021): 30. http://dx.doi.org/10.3390/v14010030.

Full text

Abstract:

Grass carp reovirus (GCRV) is a severe virus that causes great losses to grass carp culture every year, and GCRV-II is the current popular and fatal strain. VP56, fibrin on the outer surface of GCRV-II, mediates cell attachment. In this study, we firstly divided the VP56 gene into four fragments to screen the optimal antigen by enzyme-linked immunosorbent assay and neutralizing antibody methods. The second fragment VP56-2 demonstrates the optimal efficiency and was employed as an antigen in the following experiments. Bacillus subtilis were used as a carrier, and VP56-2 was expressed on the sur

APA, Harvard, Vancouver, ISO, and other styles

We offer discounts on all premium plans for authors whose works are included in thematic literature selections. Contact us to get a unique promo code!