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Relevant bibliographies by topics / Coumarin Hydrazides

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Academic literature on the topic 'Coumarin Hydrazides'

Author: Grafiati

Published: 4 June 2025

Last updated: 15 July 2025

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Journal articles on the topic "Coumarin Hydrazides"

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Nurhan G mr k o lu, Nurhan G. mr k. o. lu, and Muhammad Imran and Inam Iqbal Muhammad Imran and Inam Iqbal. "Synthesıs and Characterızatıon of New Trıazole and Coumarın-Derived Heterocyclıc Compounds Part I." Journal of the chemical society of pakistan 41, no. 6 (2019): 1097. http://dx.doi.org/10.52568/000830/jcsp/41.06.2019.

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Synthesis of ethyl ester of acetic acid containing 5-oxo-[1,2,4] triazole ring (2) was achieved by the condensation of 3-substituted-4-amino-1H-1,2,4-triazol-5(4H)-one (1) with ethyl bromoacetate in basic medium. Compound 2, was then further reacted with hydrazine hydrate to form acid hydrazide, which is 2-(4-amino-3-substituted-5-oxo-4,5-dihydro-1H-1,2,4-triazol-1-yl)acetohydrazide (3). Compound 3 was later treated with three different diverse coumarin aldehydes (6, 12, 18) resulted in the formation of arylidene hydrazides as cis–trans conformers (7, 8, 13, 14, 19, 20). In conclusion, we synt

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Nesterova, N. А., А. А. Shtro, and Е. F. Panarin. "SYNTHESIS AND ANTIVIRAL ACTIVITY OF COPOLYMERS OF OXYCINNAMIC ACID WITH N-VINYLAMIDES." Доклады Российской академии наук. Химия, науки о материалах 513, no. 1 (2023): 77–81. http://dx.doi.org/10.31857/s2686953523600320.

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Radical copolymerization of coumarin with N-vinylamides (N‑vinylpyrrolidone, N-methyl-N-vinylacetamide, N-vinylformamide) was used to prepare copolymers of various natures and varied molecular masses. After the subsequent reactions in polymer chains, water-soluble copolymers of salts of oxycinnamic acid and its hydrazides were obtained. The synthesized copolymers of salts and hydrazides of oxycinnamic acid with N-vinylamides have low cytotoxicity and demonstrate the pronounced antiviral activity against human respiratory syncytial virus (strain A2).

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Prateeptongkum, Saisuree, Nongnaphat Duangdee, and Wiratchanee Mahavorasirikul. "Evaluation of Cytotoxicity and Apoptosis Induced by Coumarin Hydrazide-Hydrazone Derivatives in Human Hepatocellular Carcinoma Cell Line." Trends in Sciences 21, no. 7 (2024): 7628. http://dx.doi.org/10.48048/tis.2024.7628.

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Coumarin and aryl hydrazide-hydrazone have attracted our attention due to their vast biological properties. Previous studies suggested that coumarin-tethered aryl hydrazide-hydrazone showed potent activities against HepG2. In the present study, we investigated the cytotoxic potency of the coumarin derivatives 1 - 3 to compare with coumarin hydrazine-hydrazone hybrids 4 and 5 against hepatocellular carcinoma HepG2 and LH86 cell lines. Among the tested coumarins, hybrids 4 and 5 showed highly potent activity against HepG2 with IC50 values of 17.82 ± 2.79 and 7.87 ± 0.88 𝜇g/mL, respectively. The

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Shaji, Neethu, Sandhya M J Nair, and Shaiju S Dharan. "Coumarin Hydrazide: Chemistry, Synthesis and Pharmacological Activities - A Review." International Journal of Research and Review 9, no. 12 (2022): 16–26. http://dx.doi.org/10.52403/ijrr.20221202.

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Coumarins are heterocyclic compound with a benzopyrone structure. Coumarins are a large group of organic compounds found in several plants even in bacteria and fungi. The biological activities of coumarins and its derivatives includes anticoagulant, anticancer, antiulcer, antifungal, anti-HIV, antimicrobial, antiosteoporosis, antioxidant and anti- inflammatory activity. Hydrazide-hydrazone derivatives act as structural sub units in many pharmacologically active compounds including coumarins to give biological activities like antimicrobial, anticancer, antifungal, anti-inflammatory, antiviral,

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Manvar, Atul, Alpeshkumar Malde, Jitender Verma, et al. "Synthesis, anti-tubercular activity and 3D-QSAR study of coumarin-4-acetic acid benzylidene hydrazides." European Journal of Medicinal Chemistry 43, no. 11 (2008): 2395–403. http://dx.doi.org/10.1016/j.ejmech.2008.01.016.

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Amer, Sara, Uri Miles, Michael Firer, and Flavio Grynszpan. "Turn-on Coumarin Precursor: From Hydrazine Sensor to Covalent Inhibition and Fluorescence Detection of Rabbit Muscle Aldolase." Molecules 29, no. 10 (2024): 2175. http://dx.doi.org/10.3390/molecules29102175.

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Hydrazine, a highly toxic compound, demands sensitive and selective detection methods. Building upon our previous studies with pre-coumarin OFF–ON sensors for fluoride anions, we extended our strategy to hydrazine sensing by adapting phenol protecting groups (propionate, levulinate, and γ-bromobutanoate) to our pre-coumarin scaffold. These probes reacted with hydrazine, yielding a fluorescent signal with low micromolar limits of detection. Mechanistic studies revealed that hydrazine deprotection may be outperformed by a retro-Knoevenagel reaction, where hydrazine acts as a nucleophile and a ba

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Journal, Baghdad Science. "Synthesis and Characterization of 3 - Substituted Coumarin." Baghdad Science Journal 13, no. 1 (2016): 89–96. http://dx.doi.org/10.21123/bsj.13.1.89-96.

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The reaction of(2-oxo-2H-chromen-3-Carbonyl chloride)(k1) with hydrazine in boiling ethanol gives the hydrazide(K2).When compound (k2) reacts with various aromatic aldehydes ,the corres ponding Schiff bases(k3–k4) achieve new series of thiazotidines (k5–k6) and azetidinones (k7–k8) obtained from the reactions of appropriate Schiff bases with mercapto acetic acid and chloro acetyl chloride respectively. All the compounds are characterized by FT-IR,1H-NMR and GC-Ms.

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Abdelmohsen, Shawkat A., and Talaat I. El Emary. "SYNTHESIS, CHARACTERIZATION AND ANTIMICROBIAL ACTIVITY OF NOVEL PYRAZOLO[3,4-b]PYRIDINES AND THEIR SPIRO-HETEROCYCLIC DERIVATIVES." JOURNAL OF ADVANCES IN CHEMISTRY 10, no. 7 (2014): 2901–15. http://dx.doi.org/10.24297/jac.v10i7.6802.

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The present work describes the synthesis of a novel series of heterocyclic moieties derived from 5-acetylpyrazolo[3,4-b]pyridine (1). The formation of chalcones (2a-d) was utilized to synthesize pyrazoline, isoxazoline and pyrimidine derivatives (3-10). Thiosemicarbazone and semicarbazone (11, 17) were utilized to synthesize other new triazolethiones, thiadiazole and selenadiazole derivatives (11-19). Some new spiro derivatives (22-25) were synthesized by the reaction of chalcone (21) of 1 and isatine with hydrazines, hydroxyl amines and thiourea. Also, The reaction of 1 with cyanoacetyl hydra

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Ibtehal K. Abdullah and Meaad K. Buniya. "Preparation and Identification of some heterocyclic compounds from cyano compounds." Tikrit Journal of Pure Science 20, no. 5 (2023): 96–105. http://dx.doi.org/10.25130/tjps.v20i5.1245.

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This article included prepared cyano acetic acid hydrazid from interaction cyano ethylacetate with hydrate hydrazen, and interaction with 2- acytel thiophene and 2- acytelpyridine it will formation of hydrazide- hydrazone derivative (I, II), and through the undergo the compounds (I,II) for chain of interactions with different chemical materials then enclosed cyclo formed derivative of (arylidene ,coumarin , aryl hydrazon , thiophene ) . Prepared compounds have been studied and Identification by physical and spectral means.

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Al-Hazmi, Ghaferah H. "Synthesis, spectroscopic characterizations and cytotoxic activities of some novel 1,2-bis-(tetrasubstituted-benzylidene) hydrazine analogues." Bulletin of the Chemical Society of Ethiopia 37, no. 6 (2023): 1503–20. http://dx.doi.org/10.4314/bcse.v37i6.16.

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ABSTRACT. The present work describes an efficient and convenient synthesis of a library of novel 1, 2-bis-(tetrasubstituted-benzylidene) hydrazine an analogue (3-7) 1,2-bis (3-methoxy-2-hydroxybenzlidene) hydrazine (3) and 1,2-bis (6-bromo-3-methoxy 2-hydroxybenzylidene) hydrazine (4), were obtained via opening of ester coumarin derivatives (1 and 2) with hydrazine hydrate under reflux. Diazotization of compound 4 with aryldiazonium chloride led to the formation of 1,2-bis (6-bromo-5-arylazo-3-methoxy-2-hydroxybenzylidene) hydrazine (6a,b). Acetylation of compounds 4 and 6a with acetic anhydri

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Dissertations / Theses on the topic "Coumarin Hydrazides"

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Benamour, Khalid. "Produits dérivés de la 2-iminoimidazolidine : synthèse, structure et résultats pharmacologiques." Université Joseph Fourier (Grenoble), 1993. http://www.theses.fr/1993GRE18013.

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Book chapters on the topic "Coumarin Hydrazides"

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Ghate, Manjunath, and Manohar V. Kulkarni. "Unusual reaction of 4-bromomethyl coumarin with hydrazine hydrate and phenyl hydrazine in ethanol and acetic acid medium: and New method of synthesis of 3-oxo- 4-benzopyridazine." In 19th International Congress on Heterocyclic Chemistry. Elsevier, 2003. http://dx.doi.org/10.1016/b978-0-08-044304-1.50151-9.

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Conference papers on the topic "Coumarin Hydrazides"

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Antonijević, Marko, Žiko Milanović, Dušica Simijonović, Zoran Marković, and Snežana Marković S. Zoran. "ANTIOXIDATIVE POTENCY AND RADICAL SCAVENGING ACTIVITY OF SELECTED COUMARIN-HYBRIDS." In 1st INTERNATIONAL Conference on Chemo and BioInformatics. Institute for Information Technologies, University of Kragujevac,, 2021. http://dx.doi.org/10.46793/iccbi21.458a.

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In previous studies, it was found that coumarins with hydrazide moiety show good antioxidative potential, while similar coumarins with hydrazone moiety are good anticancer agents. In this paper, the antioxidative potency and radical scavenging activity of two coumarin hydrazone derivatives were investigated. For this purpose, density functional theory method M062X with 6-311G++(d,p) basis set was implemented. It was found that investigated compounds exhibit good antioxidative potency, with very similar BDE values regardless of the position involved. On the other hand, PA values show that a pre

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