Relevant bibliographies by topics / Coumarine

Contents

  1. Journal articles
  2. Dissertations / Theses
  3. Books
  4. Book chapters
  5. Conference papers
  6. Reports

Academic literature on the topic 'Coumarine'

Author: Grafiati
Published: 4 June 2021
Last updated: 25 July 2025

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Journal articles on the topic "Coumarine"

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Hafiz, I. S. Abdel, A. M. Hussein, and V. F. F. Mahmoud. "Nitriles in Heterocyclic Organic Synthesis: Synthesis of Pyrano[2,3-h]coumarines, Pyrano[3,2-c]coumarines, and their Derivatives." Zeitschrift für Naturforschung B 54, no. 12 (1999): 1568–72. http://dx.doi.org/10.1515/znb-1999-1215.

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Several new 4H-pyrano[2,3-h]coumarines 5a-e were prepared by the reaction of 7-hydroxycoumarine with cinnamonitriles 1. Also, the reaction of 7-hydroxycoumarine with a mixture of aliphatic aldehydes and malononitrile afforded compounds 5f,g. Similarly, 4-hydroxycoumarine was reacted with the same reagents to give compounds 9a-g. The reaction of 9 g with different nucleophilic reagents afforded the pyrimido[4′,5′:6,5]pyrano[3,2-c]coumarin-4-one derivatives 10-12, 4-methyl-2-(ethoxymethylenamino)4H-pyrano[3,2-c]coumarine-3-carbonitrile (13) and pyrazolo[3′,4′;6,5]pyrano[3,2-c]coumarine (14) resp
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P., Aravinda Reddy Ramya Sri. S. "SYNTHESIS, CHARACTERISATION OF COUMARIN DERIVATIVES AND THEIR ANTI CANCER ACTIVITIES." Journal of Pharma Research 05, no. 12 (2016): 282–88. https://doi.org/10.5281/zenodo.7701497.

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<strong><em>ABSTRACT</em></strong> <strong><em>T</em></strong><em>wo sets of coumarines were synthesised, and their IR, 1H, and 13C NMR and mass spectra were all very well characterised. Eight a and eight c, which contain coumarine with an amide-extended chromophore, have shown promise as anti-cancer agents. Our research may lead to more widespread use of coumarines for their potential cancer-fighting properties.</em> <strong>Keywords:</strong> Coumarine, Synthesis, Characterisation and anti-cancer.
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Mulia, Melindra. "ISOLASI KUMARIN DARI KULIT BUAH LIMAU SUNDAI (Citrus nobilis Lour)." EKSAKTA: Berkala Ilmiah Bidang MIPA 18, no. 02 (2017): 137–45. http://dx.doi.org/10.24036/eksakta/vol18-iss02/70.

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Coumarin has been isolated and characteritated from rind of Citrus nobilis Lour by maseration methode with methanol. After fractionation by n-hexane and ethyl acetate, collected the phase ethyl acetate which positive of coumarin. From ethyl acetate extract coumarin have been isolated by column chromatography. The isolation results was obtain 2,159 g of pure white needle-shape crystalline with the melting point of 126,2-127,60C. Structure of the isolated coumarine was elucidated by spectroscopic methodes, UV-Vis,13C-NMR, 1H-NMR, 2D-NMR (DEPT/HSQC, COSY, NOESY, HMBC) and IR spectra. Based on the
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Mohtat, Bita, Semiramis Nahavandian, Maryam Razaghi, Saeedeh Farsijani, and Hoorieh Djahaniani. "Triphenylphosphine Mediated Synthesis of Functionalized Benzo-Fused Coumarins from Some OH Acids and Dialkyl Acetylene Dicarboxylate." Journal of Chemistry 2013 (2013): 1–5. http://dx.doi.org/10.1155/2013/289636.

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Benzo-fused coumarins are prepared from 4-quinolinol by treatment with PPh3and dialkyl acetylenedicarboxylate. Angular coumarins are prepared from 3-isoquinolinol and 7-hydroxyl coumarine with PPh3and dialkyl acetylenedicarboxylate.
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Rastija, Vesna. "Computer-Aided Design of Novel Active Components in Plant Protection." MOLECULAR SCIENCES AND APPLICATIONS 4 (May 9, 2024): 1–6. http://dx.doi.org/10.37394/232023.2024.4.1.

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The production demands highly specific environmentally and toxicologically acceptable plant protection products are increasing. Computer-aided molecular design of new active components has a great deal in developing plant protection products to avoid that long-lasting and expensive process. Computational design of future compounds and their synthesis, evaluation of their effectiveness on harmful and beneficial organisms in the soil, as well as detailed research mechanism of action at the molecular level, represents an initial stage in the long-lasting and expensive process of plant protection
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Kishkentayeva, Anarkul S., Mohammad Saleh Hamad, Mikhail A. Pokrovsky, et al. "Synthesis and Biological Evaluation of Some Coumarin–Triazole Conjugates as Potential Anticancer Agents." Scientia Pharmaceutica 93, no. 2 (2025): 16. https://doi.org/10.3390/scipharm93020016.

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Despite the discovery of many chemotherapeutic drugs that prevent uncontrolled cell division processes, the development of compounds with higher anticancer efficacy and a lower level of side effects is an important task in modern pharmaceutical chemistry. Herein, a mild and convenient method for the preparation of N1-substituted 3-(1,2,3-triazolyl-methoxycarbonyl)coumarins or bis(coumarine-3-carboxylate)bis(triazole)alkandiyl by the copper(I)-catalyzed Huisgen cycloaddition reaction of readily available coumarin-3-carboxylic acid propynyl ester with azides or diazides has been presented. The s
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Gurlui, Silviu, Ion Sandu, Nicanor Cimpoesu, Valentin Pohoata, Ioan Gabriel Sandu, and Mitachi Strat. "Nanoaggregates and Selforganization Phenomena in Polyurethane Coumarine Film." Materiale Plastice 54, no. 3 (2017): 589–92. http://dx.doi.org/10.37358/mp.17.3.4903.

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The spectroscopic and photochemical properties of polyurethane coumarine (PUC) in solid state were investigated at room temperature under once-photon excitation. One photon induced photocycloaddition of PUC was investigated and the AFM and spectroscopic FTIR analysis confirmed dimer formation. The AFM analysis shows that the fotodimerization process occurs at the surface of polymer films. The polyurethane coumarine film on CaF2 unirradiated and irradiated underline both the fotodimerization of the polymer films as well as the photoclevage of the polyurethane coumarin.
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González-Pérez, M., S. Y. Ooi, S. Martins, João P. Prates Ramalho, A. Pereira, and A. T. Caldeira. "Gaining insight into the photophysical properties of a coumarin STP ester with potential for bioconjugation." New Journal of Chemistry 42, no. 20 (2018): 16635–45. http://dx.doi.org/10.1039/c8nj03548b.

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The photophysical properties of a coumarin 392 4-sulfotetrafluorophenyl ester, C392STP (sodium (E/Z)-4-(4-(2-(6,7-dimethoxycoumarin-3-yl)vinyl)-benzoyl)-2,3,5,6-tetrafluoro-benzenesulfonate), an amine reactive coumarine with potential for bioconjungation, have been studied in different solvents.
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Rabtti, El, Maja Natic, Dusanka Milojkovic-Opsenica, et al. "Quantitative structure-toxicity relationship study of some natural and synthetic coumarins using retention parameters." Journal of the Serbian Chemical Society 77, no. 10 (2012): 1443–56. http://dx.doi.org/10.2298/jsc120716091r.

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Four lipophilicity descriptors (RM0, b, C0, PC1) for twelve coumarine derivatives were determined by reversed-phase thin-layer chromatography in order to analyze which descriptor best describes the lipophilicity of coumarines investigated. Moreover, possible chemical toxicity of coumarins, expressed as the probability of a compound to cause organ-specific health effects, was calculated using ACD/Tox Suite program. The quantitative relationships between toxicity and molecular descriptors, including experimentally determined lipophilicity descriptors obtained in current study, were investigated
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Ibrahim, Sanusi, Muhamad Iqbal, and Bustanul Arifin. "ISOLASI KUMARIN DARI BIJI PINANG (Areca catechu L.)." Jurnal Riset Kimia 1, no. 1 (2015): 50. http://dx.doi.org/10.25077/jrk.v1i1.71.

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ABSTRACT Coumarin has been isolated from seed of Areca catechu L. an ethyl acetate fraction which needle crystal products at 184 –185°C. Based on thin layer chromatography analysis using n-hexane : acetone (4 : 6) as eluent got Rf 0.6. From elemental analysis, mass spectra, ultraviolet spectra, infra red spectra, nuclear magnetic resonance spectra ( H and C NMR) ,concluded this compound was 7-hidroksi-4-metil coumarine. Keywords : Areca catechu, 7-hidroksi-4-metil kumarin.
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Dissertations / Theses on the topic "Coumarine"

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Biju-Duval, Marie. "Sécoiridoi͏̈des et coumarines du genre Fraxinus." Paris 5, 1997. http://www.theses.fr/1997PA05P220.

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Dridi, Delel. "Synthèse de dérivés coumariniques d’intérêts biologiques et antioxydants." Thesis, Université de Lorraine, 2015. http://www.theses.fr/2015LORR0335/document.

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Dans le cadre des travaux développés sur les coumarines et autres flavonoïdes au laboratoire (aurones inhibitrices de NFkB, polycycles chromaniques inhibiteurs de CDC25), le travail de la thèse a consisté à poursuivre dans ce domaine en construisant de nouvelles chalcones à partir de dérivés acétylés de coumarines par condensation avec des aldéhydes cinnamiques préparées suivant différentes méthodes. Les chalcones ainsi préparées ont été étudiées pour les effets antioxydants en utilisant la spectrophotométrie ainsi que pour l’inhibition des phosphatases CDC25<br>As part of the work developed o
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Udrea, Isabelle. "Dosage des coumarines dans les milieux biologiques." Paris 5, 1997. http://www.theses.fr/1997PA05P236.

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Korchia, Laetitia. "Auto-assemblage de copolymères amphiphiles photo-stimulables à base de polyoxazoline." Thesis, Montpellier, Ecole nationale supérieure de chimie, 2016. http://www.theses.fr/2016ENCM0005/document.

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Trois architectures de copolymères (dibloc, tribloc et hétérogreffé) amphiphiles photo-stimulables à base de polyoxazoline et de groupements photo-sensibles de type coumarine sont étudiées dans ce travail. Ces copolymères s’auto-assemblent en milieu aqueux sous forme de nanoparticules de morphologies sphériques, ovales mais également de nanofibres hélicoïdales de plusieurs micromètres de longueur. Selon les cas, les morphologies sont induites par de la cristallisation des motifs coumarine entre eux ou bien des interactions polyoxazoline-coumarine. Par ailleurs, la photo-réponse des nanoparticu
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Vialle, Émilie. "Réactivité des polyéthers ionophores et des coumarines : vers des systèmes moléculaires efficaces pour la santé animale." Phd thesis, Université Claude Bernard - Lyon I, 2011. http://tel.archives-ouvertes.fr/tel-00867741.

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L'objectif de cette thèse, réalisée en collaboration avec la société Mérial, concerne la santé animale et s'oriente vers la synthèse de molécules actives à visée préventive ou thérapeutique. Deux sujets distincts sont abordés. Dans un premier temps, le but recherché est la synthèse d'une série de molécules présentant une activité anti-coccidienne pour le traitement préventif des poulets. Quarante-trois composés originaux, issus d'une synthèse courte à deux ou trois étapes, ont été préparés par hémi-synthèse de la monensine. Quinze molécules ont été testées in vitro et trois d'entre elles montr
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Dondon, Régine. "Etude spectroscopique de complexes d'inclusion de coumarines modèles dans les cyclodextrines en vue de la vectorisation d'une coumarine naturelle extraite de Thiphasia trifolia." Toulouse 3, 2001. http://www.theses.fr/2001TOU30062.

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Klausen, Maxime. "Nouvelles sondes moléculaires photo-activées pour la délivrance de principes actifs : de la conception aux applications biologiques." Thesis, Bordeaux, 2018. http://www.theses.fr/2018BORD0077.

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La photolibération d'agents biologiques cagés par des groupements protecteurs photolabiles (PPGs) a récemment attiré un intérêt croissant en thérapie et physiologie. La combinaison de cet outil avec les avantages de l'absorption à deux photons (2PA) dans le proche IR est cependant un défi. Dans ces travaux, nous présentons deux voies différentes vers de nouveaux décageurs efficaces en 2PA.Nous élaborons d’abord une série de systèmes tandem basés sur le FRET, combinant des antennes quadrupolaires 2PA avec des modules PPGs appropriés. La modification des blocs constitutifs de ces composés nous a
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Agostinho, Daniel. "Investigation Phytochimique de plantes utilisées en médecine traditionnelle au Mozambique : Ptaeroxylon obliquum Radlk - Pyrenacantha kaurabassana Baill - Monadenium lugardae N.EBr." Thesis, Tours, 2013. http://www.theses.fr/2013TOUR3802/document.

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Les travaux menés dans cette thèse s’inscrivent dans une démarche ethno-pharmacologique visant à valoriser des plantes utilisées traditionnellement en médecine au Mozambique. Cette étude a comme but principal d’apporter des éléments chimio taxonomiques concernant des espèces végétales peu décrites et de préciser la composition métabolique de parties de plante utilisées en médecine traditionnelle, pour aboutir potentiellement à de nouvelles molécules utilisables en thérapeutique. Le travail est ainsi découpé en trois parties distinctes, chacune portant sur une plante différente.La Partie 1prése
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Diallo, Saer. "Spectrofluorimetrie des derives nitroses (nitrites et n-nitrosamines apres denitrosation alcaline) par diazotation de la coumarine 120* puis hydrolyse en 4-methylombelliferone : interet de son ionisation a l'etat excite) (doctorat : sciences pharmaceutiques)." Paris 11, 1999. http://www.theses.fr/1999PA114841.

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He, Jie. "Étude de nouveaux polymères photoactifs à base de la coumarine du nanogel aux nanoparticules." Thèse, Université de Sherbrooke, 2011. http://savoirs.usherbrooke.ca/handle/11143/5141.

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Coumarin and its derivates are one type of photoreactive chromophores which can undergo reversible dimerization and cleavage reactions at different wavelengths of light. By incorporating coumarin moieties into polymers and block copolymers (BCPs), the resulting materials become photoresponsive. They have attracted much attention due to their potential applications as shape-memory materials, photo-sensitizers for solar cells and drug delivery carriers. The research work presented in this thesis aimed at developing novel coumarin-containing polymers and BCPs, and investigating their potential ap
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Books on the topic "Coumarine"

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Melle, Josiane van. La résine de coumarone. Renaissance du Livre, 2012.

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P, Edardes Joseph, ed. Coumarin anticoagulant research progress. Nova Biomedical Books, 2008.

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Gábor, M. The pharmacology of benzopyrone derivatives and related compounds. Akadémiai Kiadó, 1986.

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United States International Trade Commission. Coumarin from the People's Republic of China. U.S. International Trade Commission, 1995.

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United States International Trade Commission. Coumarin from the People's Republic of China. U.S. International Trade Commission, 1995.

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Zeman, Marilyn Vera. evaluation of coumarin as an in vivo measure of CYP2A6 activity. National Library of Canada, 1998.

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Concannon, Shauna. A study of the isolation, synthesis, structural elucidation and biological properties of coumarin derivatives. The author], 2001.

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Ashley, Jason. Analysis of Coumarins and their detection in Galium triflorum using pyrolysis gas chromatography / mass spectrometry. Laurentian University, 1999.

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Kaipainen, Pekka. Purification and characterization of cytochrome P-450 associated with high coumarin 7-hydroxylation: An interspecies comparison. University of Kuopio, 1986.

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Casley-Smith, J. R. High-protein oedemas and the benzo-pyrones: The causes, effects, incidence and treatment of high-protein oedemas, including lymphoedema, and how these are improved by the benzo-pyrones, including the coumarins and the flavonoids. Lippincott, 1986.

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Book chapters on the topic "Coumarine"

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Gooch, Jan W. "Coumarone." In Encyclopedic Dictionary of Polymers. Springer New York, 2011. http://dx.doi.org/10.1007/978-1-4419-6247-8_2989.

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Seigler, David S. "Coumarins." In Plant Secondary Metabolism. Springer US, 1998. http://dx.doi.org/10.1007/978-1-4615-4913-0_9.

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Bährle-Rapp, Marina. "Coumarin." In Springer Lexikon Kosmetik und Körperpflege. Springer Berlin Heidelberg, 2007. http://dx.doi.org/10.1007/978-3-540-71095-0_2464.

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Gooch, Jan W. "Coumarin." In Encyclopedic Dictionary of Polymers. Springer New York, 2011. http://dx.doi.org/10.1007/978-1-4419-6247-8_2988.

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Gooch, Jan W. "Coumarone Resins." In Encyclopedic Dictionary of Polymers. Springer New York, 2011. http://dx.doi.org/10.1007/978-1-4419-6247-8_2992.

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Sarker, Satyajit D., and Lutfun Nahar. "Dietary Coumarins." In Handbook of Dietary Phytochemicals. Springer Singapore, 2019. http://dx.doi.org/10.1007/978-981-13-1745-3_37-1.

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Sarker, Satyajit D., and Lutfun Nahar. "Dietary Coumarins." In Handbook of Dietary Phytochemicals. Springer Singapore, 2021. http://dx.doi.org/10.1007/978-981-15-4148-3_37.

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Gooch, Jan W. "Coumarone-Indene Resin." In Encyclopedic Dictionary of Polymers. Springer New York, 2011. http://dx.doi.org/10.1007/978-1-4419-6247-8_2990.

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Gooch, Jan W. "Coumarone-Indene Resin." In Encyclopedic Dictionary of Polymers. Springer New York, 2011. http://dx.doi.org/10.1007/978-1-4419-6247-8_2991.

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Bährle-Rapp, Marina. "6-Methyl Coumarin." In Springer Lexikon Kosmetik und Körperpflege. Springer Berlin Heidelberg, 2007. http://dx.doi.org/10.1007/978-3-540-71095-0_6494.

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Conference papers on the topic "Coumarine"

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Rayss, Jan, Grzegorz Sudolski, Wieslaw M. Podkoscielny, et al. "The coumarine derivative as UV/VIS transducer in optical fiber UV sensor." In SPIE Proceedings, edited by Jan Wojcik and Waldemar Wojcik. SPIE, 2004. http://dx.doi.org/10.1117/12.581779.

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Kebaili, Asmaa, Fatima Belhadj, Zahira Kibou, Julio A. Seijas, M. Pilar Vazquez Tato, and Noureddine Choukchou-Braham. "A Straightforward and Efficient Approach to the Synthesis of 3-Cyano-Coumarine Derivatives." In ECSOC 2024. MDPI, 2024. https://doi.org/10.3390/ecsoc-28-20113.

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Oh, Chui-Han, and Young-Soo Choi. "Reduction of the laser threshold energy by a spectrum conversion dye." In OSA Annual Meeting. Optica Publishing Group, 1991. http://dx.doi.org/10.1364/oam.1991.thmm48.

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Due to the spectrum conversion in the mixed dye method, laser output energy was increased and laser threshold energy was reduced. Converter dye BBQ was added in two different laser dyes, LD490 and Coumarine 503 solutions. Optimum concentrations of laser dye LD490 and C503 were 4 × 10-4 M/liter and 8 × 10-4 M/liter; respectively, under Xe flashlamp pumping. Also those of converter dye BBQ were 5 × 10-6 M/liter for LD490 and 2 × 10-6 M/liter for C503. Experimental results showed that the slope efficiencies of laser output energies were increased 65% in LD490 and 61% in C503 + BBQ due to energy c
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Ali, Zaineb, Widad Alani, Suzan ALAMDAR, Muhamed Abbas, and Muntadher Alrabeeah. "Isolation of Esculetin and Umbelliferone from Viola Odorata Cultivated in Iraq." In 5th International Conference on Biomedical and Health Sciences. Cihan University-Erbil, 2024. http://dx.doi.org/10.24086/biohs2024/paper.1435.

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Abstract—Viola odorata is a species of the viola family, may be found naturally occurring over Europe and Asia. This little plant is tough and perennially herbaceous. It's also known as sweet violet and English violet. There are several medicinal uses for this flowering plant, including anticancer, antibacterial, inflammation., antioxidant activity and antipyretic activity. The phytochemical studies of Viola odorata different parts resulted in identification and isolation of different chemical constituents such as Coumarins, caffeic acid, methyl salicylate, flavonoids (Quercetin, kaempferol),
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BALEŽENTIENĖ, Ligita. "ALLELOPATHIC ACTIVITY OF INVASIVE SPECIES SOLIDAGO CANADENSIS L." In Rural Development 2015. Aleksandras Stulginskis University, 2015. http://dx.doi.org/10.15544/rd.2015.037.

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Solidago canadensis L. (Asteraceae) spread throughout the world and also is enlisted in the National list of invasive species (2012). Here the allelopathic activity of the species was assessed in terms of further understanding of their distributions over the range of native spread. The invasion success of S. Canadensis was tried to base on the estimation of the total phenolics content (TPC) in the plant aqueous leachates at different growth stages. Allelopathic impacts (total phenolics content, total concentration and dynamic, conventional coumarine units, CCU) of S. canadensis were examined d
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Radošević, Draginja, Kristina Stevanović, Vladimir Perović та Sanja Glišić. "Coumarins as promising PPARα agonists. Novel in silico insights". У 2nd International Conference on Chemo and Bioinformatics. Institute for Information Technologies, University of Kragujevac, 2023. http://dx.doi.org/10.46793/iccbi23.597r.

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The occurrence of metabolic syndrome, which includes several chronic severe diseases such as cardiovascular disease, dyslipidemia, hypertension, stroke, and type 2 diabetes mellitus, is becoming a serious public health concern on a global scale. Peroxisome proliferator-activated receptor alpha (PPARα) is a ligand-activated transcription factor that are members of the nuclear hormone receptor superfamily. PPARα plays a crucial function in regulating the expression of genes involved in fatty acid beta-oxidation and glucose homeostasis, making it a potential drug target for treating metabolic syn
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Antonijević, Marko, Žiko Milanović, Dušica Simijonović, Zoran Marković, and Snežana Marković S. Zoran. "ANTIOXIDATIVE POTENCY AND RADICAL SCAVENGING ACTIVITY OF SELECTED COUMARIN-HYBRIDS." In 1st INTERNATIONAL Conference on Chemo and BioInformatics. Institute for Information Technologies, University of Kragujevac,, 2021. http://dx.doi.org/10.46793/iccbi21.458a.

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In previous studies, it was found that coumarins with hydrazide moiety show good antioxidative potential, while similar coumarins with hydrazone moiety are good anticancer agents. In this paper, the antioxidative potency and radical scavenging activity of two coumarin hydrazone derivatives were investigated. For this purpose, density functional theory method M062X with 6-311G++(d,p) basis set was implemented. It was found that investigated compounds exhibit good antioxidative potency, with very similar BDE values regardless of the position involved. On the other hand, PA values show that a pre
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Inauen, W., T. Bombeli, H. R. Baumgartner, A. Haeberli, and P. W. Straub. "EFFECTS OF HEPARIN AND COUMARIN ON DEPOSITION OF FIBRIN, PLATELETS AND PLATELET THROMBI ON RABBIT AORTA SUBENDOTHELIUM EXPOSED TO FLOWING HUMAN BLOOD." In XIth International Congress on Thrombosis and Haemostasis. Schattauer GmbH, 1987. http://dx.doi.org/10.1055/s-0038-1643876.

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The effect of heparin and phenprocoumon on thrombogenesis induced by rabbit aorta subendothelium (SE) was investigated in 20 volunteers using an ex vivo perfusion system. Blood was drawn directly from an antecubital vein through an annular chamber with exposed SE at lOml/min flow rate (650sec−1 shear rate) for 5min. Following buffer perfusion for 15sec, the middle portion of SE was removed for plasmin digestion and adjacent segments were fixed and embedded for morphometric analysis. Perfusions were performed 20 min after i.v. injection of heparin 1000, 2500 and 5000 IU, respectively; and durin
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Broekmans, A. W., F. J. M. der Meer, and K. Briët. "TREATMENT OF CONGENITAL THROMBOTIC SYNDROMES." In XIth International Congress on Thrombosis and Haemostasis. Schattauer GmbH, 1987. http://dx.doi.org/10.1055/s-0038-1643718.

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Hereditary antithrombin III deficiency,protein C deficiency, and protein S deficiency predispose to the occurrence of venous thrombotic disease at a relatively youngage and often without an apparent cause. These disorders inherit as an autosomal dominant trait. Heterozygotes are at risk fosuperficial thrombophlebitis, thrombosis atnearly every venous site, and pulmonary embolism. Homozygous protein C deficiency may present itself with a purpura fulminans syndrome shortly after birth.In the acute phase of venous thromboembolism heparin is effective for preventing extension of the thrombotic pro
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Dimić, Dušan, Dejan Milenković, Edina Avdović, Goran Kaluđerović, and Jasmina Dimitrić Marković. "MOLECULAR DOCKING AND MOLECULAR DYNAMICS STUDIES OF THE INTERACTION BETWEEN COUMARIN-NEUROTRANSMITTER DERIVATIVES AND CARBONIC ANHYDRASE IX." In 1st INTERNATIONAL Conference on Chemo and BioInformatics. Institute for Information Technologies, University of Kragujevac,, 2021. http://dx.doi.org/10.46793/iccbi21.056d.

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Novel biologically active compounds can be obtained by the structural modification of coumarins. In this contribution, five new derivatives of 4-hydroxycoumarin with tyramine, octopamine, norepinephrine, 3-methoxytyramine, and dopamine were obtained. Their structures were optimized based on the previously obtained crystal structure of the 4-hydroxycoumarin-dopamine derivative. The special emphasis was put on the effect of various substituents on the structure of obtained compounds and intramolecular interactions governing the stability. To investigate their possible antitumor activity, molecul
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Reports on the topic "Coumarine"

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Yompakdee, Chulee, and Sittiruk Roytrakul. Molecular target of an anti-cancer compound from leaves of Clausena harmandiana (Pierre). Chulalongkorn University, 2016. https://doi.org/10.58837/chula.res.2016.32.

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Clausena harmandiana (Pierre) Guillaumin or Song faa dong (in Thai), is classified in Family Rutaceae. Previous study, a coumarin compound designated CHA-01 was isolated from leave extract of C. harmandiana with inhibitory activity against calcium signaling in a ZDS1 null mutant yeast Saccharomyces cerevisiae (delta zds1). However, not much has been known on biological activity of this coumarin. In the past, some other coumarins were reported to contain anti-cancer activity. The aim of this research was to study molecular mechanism on antiproliferation activity of CHA-01 in Jurkat T cells. The
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Wandlowski, T., and R. De Levie. The Kinetics of Formation and Dissolution of Condensed Coumarin Films. Defense Technical Information Center, 1995. http://dx.doi.org/10.21236/ada296115.

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หลุยเจริญ ชีพสุนทร, ชาลิสา, та พูลลาภ ชีพสุนทร. ผลของภาวะพร่องเอนไซม์ G6PD ต่อการเสื่อมของเซลล์ไตในโรคเบาหวาน. คณะแพทยศาสตร์ จุฬาลงกรณ์มหาวิทยาลัย, 2018. https://doi.org/10.58837/chula.res.2018.30.

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เอนไซม์ glucose 6-phosphate dehydrogenase (G6PD) เป็นเอนไซม์ที่พบได้ในทุกเซลล์ของร่างกาย มีหน้าที่สร้าง nicotinamide adenine dinucleotide (NADPH) จากวิถี pentose phosphate pathway (PPP) เพื่อช่วยป้องกันภาวะ oxidative stress ภายในเซลล์ด้วยการรักษาระดับ reduced glutathione (GSH) ความผิดปกติที่เกิดขึ้นกับเอนไซม์ G6PD ส่งผลกระทบต่อเซลล์จากภาวะ oxidative stress เช่น ภาวะพร่องเอนไซม์ G6PD สามารถเหนี่ยวนำให้เซลล์ไตเกิด apoptosis และ nephropathy นอกจากนี้ยังพบภาวะพร่องเอนไซม์ G6PD เพิ่มสูงขึ้นในผู้ป่วยเบาหวานเมื่อเทียบกับคนปกติ ด้วยเหตุนี้จึงเป็นที่มาของการศึกษาวิจัยบทบาทของภาวะพร่องเอนไซม์ G6PD ในเซล
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Galili, Gad, Harry J. Klee, and Asaph Aharoni. Elucidating the impact of enhanced conversion of primary to secondary metabolism on phenylpropanoids secondary metabolites associated with flavor, aroma and health in tomato fruits. United States Department of Agriculture, 2012. http://dx.doi.org/10.32747/2012.7597920.bard.

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• Targeted manipulating Phenylalanine (Phe) synthesis is one of the most powerful strategies to boost the biologically and economically important secondary metabolites, including phenylpropaniods, aromatic volatiles and specialized secondary metabolites. • Over-expression of the petunia MYB transcript factor, ODORANT1 (ODO1), results in significant alterations of the levels of specific phenylpropanoid compounds in plants. • Our previous studies indicated that ectopic expression of the feedback-insensitive AroG could break the bottleneck between primary and secondary metabolisms in tomato, ther
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Droby, Samir, Michael Wisniewski, Ron Porat, and Dumitru Macarisin. Role of Reactive Oxygen Species (ROS) in Tritrophic Interactions in Postharvest Biocontrol Systems. United States Department of Agriculture, 2012. http://dx.doi.org/10.32747/2012.7594390.bard.

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To elucidate the role of ROS in the tri-trophic interactions in postharvest biocontrol systems a detailed molecular and biochemical investigation was undertaken. The application of the yeast biocontrol agent Metschnikowia fructicola, microarray analysis was performed on grapefruit surface wounds using an Affymetrix Citrus GeneChip. the data indicated that 1007 putative unigenes showed significant expression changes following wounding and yeast application relative to wounded controls. The expression of the genes encoding Respiratory burst oxidase (Rbo), mitogen-activated protein kinase (MAPK)
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