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1

Lebow, Matthew E., Michael DeSarno, Damon Eugene Houghton, et al. "Relative and Absolute Platelet Count Drops As a Risk Factor for Mortality, Bleeding, and Venous Thrombosis in Hospitalized Medical Patients." Blood 126, no. 23 (2015): 2258. http://dx.doi.org/10.1182/blood.v126.23.2258.2258.

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Abstract Introduction: There is little data on the incidence and consequences of hospital-acquired (HA) platelet count drops and no consensus on how to define HA-thrombocytopenia. We evaluated the incidence of relative and absolute HA-drops in platelet count among medical patients (general medicine, cardiology, and intensive care unit) to determine their association with mortality, HA-venous thromboembolism (VTE), and HA-bleeding. Methods: Data was abstracted from the electronic medical record at the University of Vermont Medical Center, a 540-bed tertiary care hospital in Burlington, VT for a
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2

Malark, J. A., L. C. Peyton, and M. J. Galvin. "Effects of blood contamination on equine peritoneal fluid analysis." Journal of the American Veterinary Medical Association 201, no. 10 (1992): 1545–48. http://dx.doi.org/10.2460/javma.1992.201.10.1545.

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Summary Peritoneal fluid and blood was collected from 8 healthy adult horses. Four 1-ml aliquots of peritoneal fluid from each horse were then contaminated with 0 ml (normal), 0.05 ml (1 drop), 0.10 ml (2 drops), and 0.20 ml (4 drops) of blood from the same horse. Samples were analyzed for rbc count, nucleated blood cell count, total protein concentration, and nucleated cell differential count. Statistical analysis revealed no significant changes in nucleated cell number, nucleated cell differential, or total protein concentration in peritoneal samples contaminated with blood. The rbc count si
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3

Tokay, Ali, Walter A. Petersen, Patrick Gatlin, and Matthew Wingo. "Comparison of Raindrop Size Distribution Measurements by Collocated Disdrometers." Journal of Atmospheric and Oceanic Technology 30, no. 8 (2013): 1672–90. http://dx.doi.org/10.1175/jtech-d-12-00163.1.

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Abstract An impact-type Joss–Waldvogel disdrometer (JWD), a two-dimensional video disdrometer (2DVD), and a laser optical OTT Particle Size and Velocity (PARSIVEL) disdrometer (PD) were used to measure the raindrop size distribution (DSD) over a 6-month period in Huntsville, Alabama. Comparisons indicate event rain totals for all three disdrometers that were in reasonable agreement with a reference rain gauge. In a relative sense, hourly composite DSDs revealed that the JWD was more sensitive to small drops (<1 mm), while the PD appeared to severely underestimate small drops less than 0
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Siti Nur Khasanah, Maisyaroh Maisyaroh, Ade Nugraha, and Mohamad Ulinnuha. "Pembuatan Alat Monitoring Infus Berbasis NodeMCU ESP8266." Jurnal Ilmiah Informatika 6, no. 2 (2021): 105–10. http://dx.doi.org/10.35316/jimi.v6i2.1472.

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The problem of late replacement of infusion mattresses for patients in a medical institution is still common today. It still helps him closely with the nurses' negligence in monitoring the patient's infusion condition. This condition is very dangerous for the patient's health. Therefore the making of infusion monitoring equipment based on NodeMCU esp8266. This tool works by relying on the results of sensor readings that are inserted into the microcontroller which will be processed by NodeMCU. The sensor used in making this system is the sensor module, the sensor reading sensor is the intended
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T., Priyanka, Lydia K., Pushpalatha M., and Nagasuresh V. "Study of the Safety and Efficacy of 2% Sodium Cromoglycate Ophthalmic Solution and 0.1% Lodoxamide Ophthalmic Solution in Patients with Spring Catarrh in a Tertiary Care Hospital." International Journal of Pharmaceutical and Clinical Research 15, no. 9 (2023): 1021–26. https://doi.org/10.5281/zenodo.11370441.

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<strong>Introduction:&nbsp;</strong>Vernal keratoconjunctivitis comprises 0.5% of allergic eye diseases. The study is made to collate the effectiveness of drugs by following the patient to observe the reduction in signs and symptoms.&nbsp;<strong>Objectives:&nbsp;</strong>The objective of the study is to compare the effectiveness and safety of 2%sodium cromoglycate ophthalmic solution and 0.1% lodoxamide ophthalmic solution in patients with vernal keratoconjunctivitis (VKC).&nbsp;<strong>Materials and Methods:</strong>&nbsp;A randomized, comparative study conducted in patients attending the OP
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Tran, T. NINH, Dong Vinh, Quang Loc Le, et al. "COVID-19 induced immunosuppression leading to secondary infection in a non-HIV patient." Minerva Respiratory Medicine, no. 2021 June;60(2) (June 1, 2021): 59–61. https://doi.org/10.23736/S2784-8477.21.01914-3.

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Lymphopenia and immune dysfunction in COVID-19 is increasingly recognized and studied. This case report details a secondary infection following lymphopenia with CD4+ count drop in a COVID-19 patient with no history of immunosuppression or infection with HIV. The mechanism of lymphopenia, both CD4+ and CD8+ T cell count drops, in COVID-19 needs further study.
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7

Buckle, Guy, Daniel Bandari, Jeffrey Greenstein, et al. "Effect of dimethyl fumarate on lymphocyte subsets in patients with relapsing multiple sclerosis." Multiple Sclerosis Journal - Experimental, Translational and Clinical 6, no. 2 (2020): 205521732091861. http://dx.doi.org/10.1177/2055217320918619.

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Background In patients treated with dimethyl fumarate, absolute lymphocyte count decline typically occurs during the first year and then plateaus; early drops have been associated with the development of severe prolonged lymphopenia. Objective We investigated the effect of dimethyl fumarate on absolute lymphocyte counts and CD4+/CD8+ T cells in patients with relapsing–remitting multiple sclerosis treated with dimethyl fumarate in routine practice. Methods Lymphocyte data were collected via medical chart abstraction. Primary endpoint: change from baseline in absolute lymphocyte count and CD4+/C
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8

NAPOLI, DENISE. "Rosacea Lesion Count Drops With Use of Green Tea Cream." Family Practice News 37, no. 8 (2007): 25. http://dx.doi.org/10.1016/s0300-7073(07)70488-7.

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9

Palanzo, David A., Debra L. Zarro, Norman J. Manley, et al. "Effect of Carmeda® BioActive Surface coating versus Trillium™ Biopassive Surface coating of the oxygenator on circulating platelet count drop during cardiopulmonary bypass." Perfusion 16, no. 4 (2001): 279–83. http://dx.doi.org/10.1177/026765910101600403.

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An investigation was conducted to evaluate the effect that surface coating of the hollow-fiber membrane oxygenator had on circulating platelet count drop during cardiopulmonary bypass (CPB). Sixty patients undergoing non-emergency myocardial revascularization for coronary artery disease were randomly divided into two groups. Group one ( n = 32) received the Carmeda®-coated Maxima- Plus PRF oxygenator while the patients in Group two ( n = 28) received the Trillium™-coated Affinity oxygenator during CPB. The net platelet count drops for the pump specimen (15-20 min after the initiation of bypass
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10

Tirsi, Andrew, Richard Adamovich-Zeitlin, Hanwen Yang, et al. "Pattern Electroretinogram in Glaucoma Suspects with Signs of Conversion: Diagnosis, Assessment, and Monitoring Treatment – Case Report." Case Reports in Ophthalmology 15, no. 1 (2024): 791–801. http://dx.doi.org/10.1159/000542199.

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Introduction: The purpose of this case report was to describe a case of a 61-year-old female glaucoma suspect with signs of conversion into early glaucoma. Treatment with prostaglandin analog drops was started. Case Presentation: A 61-year-old female presented with worsening vision in the left eye, elevated intraocular pressure (IOP) of 25 mm Hg in the right eye and 21 mm Hg in the left eye. Humphrey visual field tests showed borderline glaucomatous changes, but pattern electroretinogram (PERG) confirmed objective retinal ganglion cell (RGC) dysfunction in both eyes. Prostaglandin analog drops
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11

Abu Shaqra, Qasem M., Rania M. Al-Groom, and Aseel Q. Abu Shaqra. "Antimicrobial Effectiveness in Eye Drops: Limited Sterility versus Reduction in Microbial Count." PDA Journal of Pharmaceutical Science and Technology 74, no. 3 (2020): 309–17. http://dx.doi.org/10.5731/pdajpst.2019.009845.

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12

Ogren, Paul, Steve Nelson, and Ian Henry. "Using a Diode Laser Pointer to Count Drops and Automate Titration Systems." Journal of Chemical Education 78, no. 3 (2001): 353. http://dx.doi.org/10.1021/ed078p353.

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13

Akande, E.A., J.A. Adeyanju, O.A. Oladipo, and F.F. Oyetunji. "Effects of Different Packaging Materials on the Shelf Stability of Ginger Juice." Greener Journal of Science, Engineering and Technological Research 4, no. 2 (2014): 38–44. https://doi.org/10.15580/gjsetr.2014.2.031014139.

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Ginger (<em>Zingiber officialis rosoe)</em>&nbsp;is an important spice crop of the world and plays valuable roles as food additives (spices) in foods. &nbsp;Acceptable juice has been produced from ginger. However, there are dearths of information on its shelf life study using appropriate packaging materials. Hence, the aim of this research work is to study the effect of different packaging materials on the shelf stability of ginger juice. Ginger juice is produced from ginger rhizomes through sorting, washing, peeling, milling, juice extraction, sieving, application of additives (preservatives,
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14

Palanzo, David A., Debra L. Zarro, Ralph M. Montesano, and Norman J. Manley. "Albumin in the cardiopulmonary bypass prime: how little is enough?" Perfusion 14, no. 3 (1999): 167–72. http://dx.doi.org/10.1177/026765919901400303.

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Previous studies have demonstrated high transoxygenator pressures with noncoated hollow-fiber membrane oxygenators. These reports have been associated with dramatic platelet count drops during cardiopulmonary bypass (CPB). It has also been shown that adding human albumin to the prime of the bypass circuit reduces, if not eliminates, these problems. This study was conducted to determine what is the smallest amount of albumin added to the prime that will still display its protective effects. Eighty patients undergoing nonemergency open-heart surgery were randomly divided into four groups. Groups
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15

Burgar, C. G., G. J. Winter, and A. P. Shepherd. "Drop-counting flow computer." American Journal of Physiology-Heart and Circulatory Physiology 248, no. 2 (1985): H286—H290. http://dx.doi.org/10.1152/ajpheart.1985.248.2.h286.

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An inexpensive microcomputer (VIC-20) was adapted to count drops of fluid and calculate flow. To minimize both the expense and the bench space occupied by the flow computer, we eliminated the need for a video monitor by employing a liquid crystal alphanumeric display. Neither tape recorders nor disk drives are needed because the flow-computing program resides in a “game cartridge.” Furthermore, the power supply of the computer powers the interface and display. The computer's real-time clock is utilized to time intervals between drops falling through an infrared beam. The computed flow values a
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16

Günaydın, Ahmet Can, Mehmet Halkacı, Fatih Ateş, and Hüseyin Selçuk Halkacı. "Experimental Research of the Usability on Double Acting Intensifiers in Hydroforming." MATEC Web of Conferences 220 (2018): 04006. http://dx.doi.org/10.1051/matecconf/201822004006.

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The hydroforming method is especially used for forming lightweight materials like aluminum, magnesium alloys, high strength steels or materials that have limited formability. Intensifiers are the most important component of hydroforming presses. Nowadays single-acting intensifiers are used in hydroforming presses. Single-acting intensifiers provide pressurized liquid by forwarding movement of the piston through one direction and their volumes are limited. The mass of the intensifiers increases significantly depending on their liquid volume capacity and this causes high manufacturing costs. For
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17

Palanzo, David A., Debra L. Zarro, Norman J. Manley, Ralph M. Montesano, Michael Quinn, and Patricia A. Gustafson. "Effect of surface coating on platelet count drop during cardiopulmonary bypass." Perfusion 14, no. 3 (1999): 195–200. http://dx.doi.org/10.1177/026765919901400307.

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This study was designed to investigate the effect of surface coating on platelet count drop during cardiopulmonary bypass (CPB). Sixty patients undergoing open-heart surgery were randomly divided into three groups each receiving a different type of coated hollow-fiber membrane oxygenator. The patients were given either an uncoated oxygenator (noncoated group), an oxygenator coated with Carmeda® (Carmeda group) or an uncoated oxygenator with albumin in the priming solution (albumin group). Comparisons were made in platelet count pre-CPB, on bypass (15-25 min) and during the warming period. Calc
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18

Forthmann, Boris, and Philipp Doebler. "Reliability of researcher capacity estimates and count data dispersion: a comparison of Poisson, negative binomial, and Conway-Maxwell-Poisson models." Scientometrics 126, no. 4 (2021): 3337–54. http://dx.doi.org/10.1007/s11192-021-03864-8.

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AbstractItem-response models from the psychometric literature have been proposed for the estimation of researcher capacity. Canonical items that can be incorporated in such models to reflect researcher performance are count data (e.g., number of publications, number of citations). Count data can be modeled by Rasch’s Poisson counts model that assumes equidispersion (i.e., mean and variance must coincide). However, the mean can be larger as compared to the variance (i.e., underdispersion), or b) smaller as compared to the variance (i.e., overdispersion). Ignoring the presence of overdispersion
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19

Loubiere, Sandrine, Kamal Marhoum el Filal, Mustapha Sodqi, et al. "When to Initiate Highly Active Antiretroviral Therapy in Low-Resource Settings: The Moroccan Experience." Antiviral Therapy 13, no. 2 (2008): 241–52. http://dx.doi.org/10.1177/135965350801300209.

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Background The aim of this study was to assess the cost-effectiveness of HIV treatment alternatives – with and without highly active antiretroviral therapy (HAART) – within alternative strata based on the CD4+ T-cell count at the initiation of treatment in a low-resource setting. Methods A retrospective observational study was conducted following 286 HIV-positive individuals admitted to the principal teaching hospital in Casablanca, Morocco, between 1995 and 2002. Patients were stratified by CD4+ T-cell count and regression models were fitted to determine risk of opportunistic infection. Data
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20

Aphle, Parth, Snigdha Suman Dalua, Poorva Tiwari, and Ramachandran Valavan. "Evaluating the Efficacy and Safety Profile of Good Morning™ Constipation Drops in a Loperamide-Induced Rat Model." Advanvcements in Homeopathic Research 8, no. 4 (2024): 19–28. http://dx.doi.org/10.48165/ahr.2023.8.4.1.

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Introduction: Constipation is a prevalent gastrointestinal condition globally, often managed with conventional laxatives that may cause side effects and dependency. Homeopathy, offering a holistic approach through diluted natural substances, aims to stimulate the body's self-healing mechanism. This study evaluates Good Morning™ drops, an innovative homeopathic formulation designed to safely and effectively manage constipation. Using a rat model of Loperamide-induced constipation, we evaluated its safety and efficacy, unveiling promising results.Materials and Methods: A rat model of Loperamide
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21

Oscar, Jennifer, and Freddy Ciptono. "Comparison Between Platelet Count and Hematocrit Levels in Primary and Secondary Dengue Hemorrhagic Fever Infection." INDONESIAN JOURNAL OF HEALTH SCIENCES RESEARCH AND DEVELOPMENT (IJHSRD) 5, no. 1 (2023): 106–11. http://dx.doi.org/10.36566/ijhsrd/vol5.iss1/155.

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Background: Dengue hemorrhagic fever is an infectious ailment that exhibits a significantly elevated incidence rate in Indonesia. Dengue hemorrhagic fever can be classified into primary and secondary infection, where the secondary infection tends to cause more severe clinical manifestations. Hematocrit and platelet count are essential parameters observed in dengue hemorrhagic fever. This study aimed to analysed the existence of statistically significant differences in the level of hematocrit and platelet count between primary and secondary dengue hemorrhagic fever infections. Methods: This stu
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22

Nur, Mahira Aisyah Putri, Sudaryanto Sudaryanto, Endang Sri Lestari, and Erwin Kresnoadi. "The Effects of Green Betel Leaf (Piper betle) Extract Eye Drops on the Number of Staphylococcus aureus Colonies in Conjunctivitis Wistar Rats Model (Rattus novergicus)." Majalah Obat Tradisional 26, no. 2 (2021): 123. http://dx.doi.org/10.22146/mot.65242.

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Irrational use of antibiotics can cause resistance to some diseases such as bacterial conjunctivitis caused by Staphylococcus aureus. Previous research said that green betel leaf (Piper betle) contains antimicrobial compounds such as eugenol, cavalry, tannins, saponins, and flavonoids which also have antiseptic power as well as antibiotics. This study aims to prove the decrease in the number of Staphylococcus aureus colonies after giving green betel leaf eye drops (Piper betle) to conjunctivitis Wistar rats (Rattus norvegicus). This research was true experimental with a pretest-posttest contro
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23

Rogula, Basia, Greta Lozano-Ortega, and Karissa M. Johnston. "A Method for Reconstructing Individual Patient Data From Kaplan-Meier Survival Curves That Incorporate Marked Censoring Times." MDM Policy & Practice 7, no. 1 (2022): 238146832210776. http://dx.doi.org/10.1177/23814683221077643.

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Introduction. Access to individual patient data (IPD) can be advantageous when conducting cost-effectiveness analyses or indirect treatment comparisons. While exact times of censoring are often marked on published Kaplan-Meier (KM) curves, an algorithm for reconstructing IPD from such curves that allows for their incorporation is presently unavailable. Methods. An algorithm capable of incorporating marked censoring times was developed to reconstruct IPD from KM curves, taking as additional inputs the total patient count and coordinates of the drops in survival. The reliability of the algorithm
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24

Givens, M., M. Marley, P. Galik, K. Riddell, and D. Stringfellow. "211 LACTOFERRIN INHIBITS BOVINE HERPESVIRUS-1 IN CELL CULTURE AND ALLOWS NORMAL DEVELOPMENT OF IN VITRO-PRODUCED EMBRYOS." Reproduction, Fertility and Development 18, no. 2 (2006): 213. http://dx.doi.org/10.1071/rdv18n2ab211.

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Lactoferrin is an iron-binding glycoprotein found in milk, saliva, tears, and other exocrine secretions. It is known to have in vitro antiviral effects against human, feline, and canine herpesviruses. In addition, lactoferrin is known to be safe in cell culture. Bovine herpesvirus-1 (BHV-1) is a likely contaminant of in vitro embryo production. Further, trypsin treatment is not completely effective in removing the virus from these embryos. We hypothesized that a nontoxic concentration of lactoferrin might prevent replication of BHV-1 within in vitro embryo production systems. Thus, the specifi
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25

Ako, Andrew Ako, George Elambo Nkeng, and Gloria Eyong Eneke Takem. "Water quality and occurrence of water-borne diseases in the Douala 4th District, Cameroon." Water Science and Technology 59, no. 12 (2009): 2321–29. http://dx.doi.org/10.2166/wst.2009.268.

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The monthly occurrence and mean age distribution of water-borne diseases in the Douala 4th District, Cameroon (1995–2006) were studied and probable causes of diseases spread were established. Diseases of interest included gastroenteritis, amoebic dysentery, typhoid fever and cholera. Water-borne disease occurrence was observed to follow a seasonal pattern with peaks occurring between the months of January and May followed by drops between June and October and rose again from November. Children below 5 years were found to be more vulnerable to diarrhoea, gastroenteritis, amoebic dysentery while
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26

Papanikolaou, P., G. P. Swanson, S. Stathakis, M. Fakhreddine, and P. Mavroidis. "Estimation of Dose-Response Correlations Regarding Significant Blood Count Drops After Radiotherapy for Prostate Cancer." International Journal of Radiation Oncology*Biology*Physics 111, no. 3 (2021): e290. http://dx.doi.org/10.1016/j.ijrobp.2021.07.921.

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27

Berg, Maarten ten, Patricia Van den Bemt, Albert huisman, Fred Schobben, Toine Egberts, and Wouter Van Solinge. "Adherence to Guidelines for Monitoring for Heparin-Induced Thrombocytopenia in Patients Treated with Low Molecular Weight Heparin." Blood 112, no. 11 (2008): 1282. http://dx.doi.org/10.1182/blood.v112.11.1282.1282.

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Abstract Laboratory monitoring for early detection of adverse drug reactions is recommended for many drugs. For patients treated with low molecular weight heparin (LMWH), the Summary of Product Characteristics (SPC) and clinical guidelines recommend to monitor the platelet count for heparin-induced thrombocytopenia (HIT), a potentially life-threatening adverse event, characterised by a typical drop in platelet count. When the platelet count drops without obvious explanation in these patients, testing for heparin-platelet factor 4 antibodies (HPF4-Ab) and initiating alternative anticoagulation
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28

Alshehri, Omar Abdulaziz, Raed Eid Alsulami, Bader Saad Alqahtani, Osama Saeed Alamri, and Mosa Alharbi. "Corneal Endothelial Cell Loss Following Airbag Injury." Clinical Medicine Insights: Case Reports 15 (January 2022): 117954762211038. http://dx.doi.org/10.1177/11795476221103824.

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Purpose: To report a rare incidence of corneal endothelial cell loss following airbag injury. Observation: A 27-year-old female who sustained a motor vehicle accident with airbag deployment presented with hand motion vision in the left eye. Ocular examination demonstrated corneal abrasion, significant corneal stromal edema with descemet folds, and a central pachymetry of 999 µm. The patient was managed with topical steroids and antibiotic drops. One week later, specular microscopy revealed a central endothelial cell count of 2200/mm2 with pleomorphism, polymegathism, and a decreased central co
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29

Yadav, Neha, Sumit Sachdeva, Manisha Rathi, Sonia Chhabra, Shreay Vashisth, and Dinkar Yadav. "Comparison of efficacy of topical bepotastine besilate and alcaftadine in patients with vernal keratoconjunctivitis." Indian Journal of Clinical and Experimental Ophthalmology 10, no. 2 (2024): 319–24. http://dx.doi.org/10.18231/j.ijceo.2024.057.

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To compare efficacy of bepotastine besilate (1.5%) versus alcaftadine (0.25%) in patients with vernal keratoconjunctivitis.This comparative, randomized, single-blind and prospective study was conducted on 100 patients diagnosed with VKC, who were allocated to receive either of the two treatment groups. Group A received Alcaftdine eye drops once daily, while Group B received bepotastine besilate twice daily for 8 weeks. The efficacy assessment was done at baseline and then at 4 and 8 weeks post-treatment using following parameters - Primary endpoints included clinical symptoms score and clinica
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Reshika, N. N., and A. S. Vickram. "Comparative Studies on the Effect of Tris -Egg Yolk and Soya Milk Based Semen Extender on various Semen Parameters for Effective Long Term Cryopreservation." CARDIOMETRY, no. 25 (February 14, 2023): 1054–61. http://dx.doi.org/10.18137/cardiometry.2022.25.10541061.

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Aim: To analyze the most effective Novel semen extender for long time cryopreservation among Tris egg yolk extender and Soya milk extender. Materials and Methods: The sample size was calculated using clinCalc.com with an alpha error-threshold at 0.05, 95 % confidence interval, G power at 80 %, and enrolment ratio 1. The study was repeated 14 times (N=14) and was measured using statistical Independent Samples Test. The study contained a total sample size of 28 with 2 different groups. Tris egg yolk and soya milk based novel semen extenders were added to the collected semen samples and few drops
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Iftikhar, Mahnoor, Minah Nisar, Aqsa Zahoor, et al. "Automated IV Infusion Control System Design and Development for Medical Use." Pakistan Journal of Scientific Research 3, no. 1 (2023): 106–12. http://dx.doi.org/10.57041/pjosr.v3i1.969.

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For patients suffering from pathological conditions, Intravenous infusion serves to be the go-to treatment, it requires for a medical practitioner to set up the IV infusion device up as per the doctors’ instructions, followed by periodic supervision as abnormalities may occur. The objective of this paper is to demonstrate the construction of an automated intravenous infusion control system. Medical and laboratory fluid control has previously been achieved using pressure-based flow sensing, ultrasonic flow measurement, optical flow sensors, capacitive flow sensing, and thermal flow sensing. Due
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Akingbola, Titilola S., Chinedu Anthony Ezekekwu, Joseph Yaria, et al. "Assessment of Bone Marrow Function in Sickle Cell Anaemia Patients Using Corrected Reticulocyte Counts." Blood 126, no. 23 (2015): 4581. http://dx.doi.org/10.1182/blood.v126.23.4581.4581.

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Abstract Introduction: Chronic hemolysis occurs in sickle cell anemia as a result of recurrent sickling and other abnormalities of the red blood cells including eryptosis. Exuberant reticulocytosis is anticipated to partially compensate for the resultant anemia. Sickle cell anemia patients may also have aplastic crisis, bone marrow (BM) infarction and erythropoietin deficiency which could lead to reticulocytopenia despite the anemia. High degree of reticulocytosis among asymptomatic infants with sickle cell anemia has been associated with an increased risk of death or stroke during childhood.
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Wang, Qin, Jiayang Chen, Yuzhe Zhou, et al. "Contact-Distil: Boosting Low Homologous Protein Contact Map Prediction by Self-Supervised Distillation." Proceedings of the AAAI Conference on Artificial Intelligence 36, no. 4 (2022): 4620–27. http://dx.doi.org/10.1609/aaai.v36i4.20386.

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Accurate protein contact map prediction (PCMP) is essential for precise protein structure estimation and further biological studies. Recent works achieve significant performance on this task with high quality multiple sequence alignment (MSA). However, the PCMP accuracy drops dramatically while only poor MSA (e.g., absolute MSA count less than 10) is available. Therefore, in this paper, we propose the Contact-Distil to improve the low homologous PCMP accuracy through knowledge distillation on a self-supervised model. Particularly, two pre-trained transformers are exploited to learn the high qu
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Al-Kulabi, Ali, Louis Gooden, and Ijeoma F. Uchegbu. "Nanoparticulate Mycophenolic Acid Eye Drops - Analytical Validation of a High Performance Liquid Chromatography Assay and Stability Studies." Pharmaceutical Nanotechnology 9, no. 2 (2021): 101–10. http://dx.doi.org/10.2174/2211738509666210111161110.

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Background: Mycophenolic acid (MPA), an immunosuppressive agent, is used orally to reduce corneal graft rejection. However, its oral use is associated with gastrointestinal side effects. Objectives: This study aims to prepare: MPA nanoparticle eye drops and a validated analytical method. Methods: Aqueous MPA eye drops were prepared by nanoencapsulation of MPA using nanomerics MET (N-palamitoyl-N-monomethyl-N,N-dimethyl-N,N,N-trimethyl-6-O-glycolchitosan) at a MET and MPA ratio of 7.5: 1 g g-1 in the presence of glycerol (2.75% w/w). A validated MPA formulation drug substance assay was then con
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Libera, Kacper, Len Lipman, and Boyd R. Berends. "Small Contaminations on Broiler Carcasses Are More a Quality Matter than a Food Safety Issue." Foods 12, no. 3 (2023): 522. http://dx.doi.org/10.3390/foods12030522.

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Depending on the interpretation of the European Union (EU) regulations, even marginally visibly contaminated poultry carcasses could be rejected for human consumption due to food safety concerns. However, it is not clear if small contaminations actually increase the already present bacterial load of carcasses to such an extent that the risk for the consumers is seriously elevated. Therefore, the additional contribution to the total microbial load on carcasses by a small but still visible contamination with feces, grains from the crop, and drops of bile and grease from the slaughter line was de
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Malahat, Amatur R., Sudhakar Kodudula, and Vijaya L. Gali. "A prospective comparative study to evaluate the efficacy and safety of olopatadine eye drops and bepotastine eye drops in subjects of vernal kerato conjunctivitis." International Journal of Basic & Clinical Pharmacology 9, no. 5 (2020): 706. http://dx.doi.org/10.18203/2319-2003.ijbcp20201743.

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Background: Vernal keratoconjunctivitis (VKC) is an allergic eye disease that especially affects young boys. Both olopatadine and bepotestine are dual acting drugs that provide rapid symptomatic relief coupled with the long-term disease-modifying benefit. The present study is conducted to compare the efficacy and safety of olopatadine eye drops and bepotastine eye drops in patients of vernal keratoconjunctivitis.Methods: A prospective, randomized, parallel-group, comparative study is conducted over a period of 4 weeks on paediatric patients with VKC. 50 patients are recruited and randomized in
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Achfidawati, Hilda Nur, Ulfa Elfiah, and Elly Nurus Sakinah. "Analysis of Morphology and Erythrocyte Count in Rat after Electrical Exposure." Journal of Agromedicine and Medical Sciences 5, no. 1 (2019): 25. http://dx.doi.org/10.19184/ams.v5i1.6806.

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Electrical burns cause high mortality and morbidity and various complications, although the incidence is only 4% of all burns. Joule heating phenomenon occurs in electric burn patients which cause changes in erythrocyte morphology resulting hypercoagulability that contribute to the formation of thrombus. Changes in erythrocyte morphology may cause tissue oxygenation disorders and decrease in erythrocyte count leading to hypoxia. Until now there have been no reports of changes in erythrocyte morphology and reduction in the number of erythrocytes in burn patients due to electricity. This study a
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Liu, Fang, Xiaoxue Fan, Xilei Sun, et al. "Characterization of a Mass-Produced SiPM at Liquid Nitrogen Temperature for CsI Neutrino Coherent Detectors." Sensors 22, no. 3 (2022): 1099. http://dx.doi.org/10.3390/s22031099.

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Silicon Photomultiplier (SiPM) is a sensor that can detect low-light signals lower than the single-photon level. In order to study the properties of neutrinos at a low detection threshold and low radioactivity experimental background, a low-temperature CsI neutrino coherent scattering detector is designed to be read by the SiPM sensor. Less thermal noise of SiPM and more light yield of CsI crystals can be obtained at the working temperature of liquid nitrogen. The breakdown voltage (Vbd) and dark count rate (DCR) of SiPM at liquid nitrogen temperature are two key parameters for coherent scatte
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Braul, Larry, T. Viraraghavan, and Darrell Corkal. "Cold Water Effects on Enhanced Coagulation of High DOC, Low Turbidity Water." Water Quality Research Journal 36, no. 4 (2001): 701–17. http://dx.doi.org/10.2166/wqrj.2001.037.

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Abstract Prairie farm reservoirs are usually low in turbidity and contain high concentrations of dissolved organic carbon (DOC). Some are treated with aluminum sulfate in late fall when the water drops below 3°C, often with poor turbidity reduction results. Jar tests using aluminum sulfate were conducted to study the effect of water temperature on enhanced coagulation of a typical high DOC prairie water. Jar tests showed that temperature affects turbidity, particle counts and total residual aluminum but does not affect DOC, UV254 absorbance and colour reduction. Turbidity of the treated water
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Er, H., Y. Turkoz, I. H. Ozerol, and E. Uzmez. "Effect of Nitric Oxide Synthase Inhibition in Experimental Pseudomonas keratitis in Rabbits." European Journal of Ophthalmology 8, no. 3 (1998): 137–41. http://dx.doi.org/10.1177/112067219800800303.

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Purpose The aim of this study was to assess the efficacy of the nitric oxide synthase inhibitor L-NG-nitro-arginine-methyleser (L-NAME) in the treatment of experimental Pseudomonas keratitis. Methods Twelve young New Zealand white rabbits were given intrastromal injections of Pseudomonas aeruginosa strains. Twenty-four hours later, the rabbits were randomly divided into four groups: group 1 was treated with topical 0.3% ciprofloxacin drops and a single subconjunctival injection of L-NAME (150 mg/kg); group 2 received topical 0.3% ciprofloxacin drops alone; group 3 received a single subconjunct
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Irsyam, Muhammad. "PERANCANGAN SISTEM PENGATUR TETESAN INFUS KESEHATAN BERBASIS ARDUINO UNO." SIGMA TEKNIKA 5, no. 1 (2022): 089–99. http://dx.doi.org/10.33373/sigmateknika.v5i1.4126.

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AbstrakPerkembangan dalam dunia kesehatan yang semakin canggih menyebabkan tuntutan akan kemudahan dan ketepatan. Demikian halnya dengan perkembangan ilmu dan teknologi di bidang alat – alat dan obat-obat kesehatan. Salah satu obat yang yang digunakan adalah infus atau perawatan intravena. Dalam penggunaan infus secara manual, perawat harus menghitung tetesan infuse untuk menentukanjumlah tetesan yang sesuai selama beberapa menit. Hal ini memerlukan tingkat ketelitian yang rendah dan bahkan bisa saja mengakibatkan kesalahan jika perawat tidak teliti dalam mengatur jumlah tetesan yang sesuai. D
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Madden, L. V., L. L. Wilson, and N. Ntahimpera. "Calibration and Evaluation of an Electronic Sensor for Rainfall Kinetic Energy." Phytopathology® 88, no. 9 (1998): 950–59. http://dx.doi.org/10.1094/phyto.1998.88.9.950.

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A novel sensor for measuring the kinetic energy of impacting raindrops, developed based on a soil-mass erosion sensor, was tested in the laboratory, with a rain simulator, and in the field. Drop impactions on the sensor—consisting of a piezoelectric crystal and associated electronics—produce an electrical charge that equals a fixed amount of energy. Calibration of the sensor was done in the laboratory using water drops of known diameter impacting with known velocity, and thus, with known kinetic energy. The relationship between pulse-count output of the sensor minus the background pulse counts
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Morse, J. G., N. J. Sakovich, and M. P. Parrella. "Evaluation of Baits for Control of Brown Garden Snail in California, 1984." Insecticide and Acaricide Tests 10, no. 1 (1985): 54–55. http://dx.doi.org/10.1093/iat/10.1.54a.

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Abstract Various bait formulations of metaldehyde, methiocarb and larvin were tested for control of brown garden snails in an 11-year-old grapefruit grove (NS rows rowspacing 24 x 12 ft) in Buckhorn CA using 4 single-tree replicates per treatment. Trees were devoid of weeds, but some leaf litter had accumulated under each tree. The grove was irrigated on 22 May, 4 Jun, and 11 Jun using low volume sprinklers, 1 located between each tree in a row. Counts of live snails pretreatment and dead snails posttreatment were taken within 1-yard-square counting frames (positions marked by stakes) which we
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Dubay, Sareta K., Dorian Dwarika, Ronnie Bhola, and Balakrishna Vineeth Kumar. "Long-term outcome of pars plana Ahmed valve implant and vitrectomy in eyes with refractory glaucoma." Medical hypothesis discovery and innovation in ophthalmology 11, no. 1 (2022): 44–51. http://dx.doi.org/10.51329/mehdiophthal1445.

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Background: Pars plana vitrectomy with implantation of an Ahmed glaucoma valve in the vitreous cavity has been reported with a success rate in the management of refractory and neovascular glaucoma. This study aimed to present the outcomes of pars plana Ahmed glaucoma valve (PPAV) surgical implantation in cases with refractory glaucoma.&#x0D; Methods: In this single-center, retrospective, comparative study, 87 consecutive patients diagnosed with refractory glaucoma who underwent PPAV surgical implantation between October 2015 and October 2019 were evaluated. A successful post-op outcome was def
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Islam, MA, MHK Basunia, A. Rahman, et al. "Effect of coagulants on the chemical and microbial quality of fresh cheese." Bangladesh Journal of Animal Science 50, no. 2 (2022): 73–79. http://dx.doi.org/10.3329/bjas.v50i2.58024.

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This experiment was conducted to explore the effect of various types of coagulants on the chemical and microbiological quality of cheese made from fresh milk. Fresh cheese was manufactured using four different coagulants; microbial rennet (0.7%), lactic acid (1.5%), papaya latex (5 drops in 100 mL water) and calf rennet (100 g calf abomasum soaked overnight in 1000 mL mixture of water and milk in 3:1 ratio and then filtrate) under laboratory condition and analyzed for cheese yield, proximate composition, acidity, pH and coagulation time. In addition, standard plate count and coliform count was
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Elshoeibi, Amgad M., Khaled Ferih, Ahmed Adel Elsabagh, et al. "Applications of Artificial Intelligence in Thrombocytopenia." Diagnostics 13, no. 6 (2023): 1060. http://dx.doi.org/10.3390/diagnostics13061060.

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Thrombocytopenia is a medical condition where blood platelet count drops very low. This drop in platelet count can be attributed to many causes including medication, sepsis, viral infections, and autoimmunity. Clinically, the presence of thrombocytopenia might be very dangerous and is associated with poor outcomes of patients due to excessive bleeding if not addressed quickly enough. Hence, early detection and evaluation of thrombocytopenia is essential for rapid and appropriate intervention for these patients. Since artificial intelligence is able to combine and evaluate many linear and nonli
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Rak, Tibor, Evelin Patko, Edina Szabo, et al. "Combined Herbal Eye Drops Exhibit Neuroprotective and Intraocular Pressure-Reducing Effects in a Glaucoma Rat Model." Antioxidants 14, no. 5 (2025): 549. https://doi.org/10.3390/antiox14050549.

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(1) Background: Glaucoma is a multifactorial group of diseases characterized by progressive optic neuropathy. Intraocular pressure (IOP) is the only successfully modifiable risk factor for all forms of glaucoma. However, recent research has highlighted the reduction of oxidative stress and neuroinflammation as promising therapeutic targets. In this study, we evaluated the antiglaucomatous effects of a combined herbal extract applied as eye drops in a rat model of glaucoma. (2) Methods: Sprague Dawley rats were divided into four groups: healthy controls, glaucomatous animals treated with preser
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Southan, Christopher. "Last rolls of the yoyo: Assessing the human canonical protein count." F1000Research 6 (April 7, 2017): 448. http://dx.doi.org/10.12688/f1000research.11119.1.

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In 2004, when the protein estimate from the finished human genome was only 24,000, the surprise was compounded as reviewed estimates fell to 19,000 by 2014. However, variability in the total canonical protein counts (i.e. excluding alternative splice forms) of open reading frames (ORFs) in different annotation portals persists. This work assesses these differences and possible causes. A 16-year analysis of Ensembl and UniProtKB/Swiss-Prot shows convergence to a protein number of ~20,000. The former had shown some yo-yoing, but both have now plateaued. Nine major annotation portals, reviewed at
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Vahidy, Ahsan A., and Farzana A. Shafiq. "KARYOMORPHOLOGICAL STUDIES ON HIPPEASTRUM SPECIES." HortScience 27, no. 6 (1992): 586d—586. http://dx.doi.org/10.21273/hortsci.27.6.586d.

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Chromosome morphology of locally available cultivars of Hippeastrum (Basionym: Amaryllis) was studied from the root tips of 60 bulbs. Optimum contraction with good resolution of chromosomes was obtained when a mixture of 0.0lg colchicine, 0.005g 8-hydroxyquinoline and 5 drops of DMSO in 20ml of distilled water was used as pretreatment. A count of 2n=22 was confirmed in all the bulbs except ten in which the diploid chromosome number was 55. Chromosomes of 2n=22 cytotype were very long to medium, while those in 2n=55 cytotype were long to small. Very long chromosomes were submetacentric, long ch
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Ellis, Robert W., Lewis C. Strauss, Joseph M. Wiley, Thomas M. Killmond, and Robert W. Ellis. "A Simple Method of Estimating Cerebrospinal Fluid Pressure During Lumbar Puncture." Pediatrics 89, no. 5 (1992): 895–97. http://dx.doi.org/10.1542/peds.89.5.895.

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It is often difficult to measure cerebrospinal fluid (CSF) pressure in children. CSF flow through a spinal needle is described by the equation: Flow = pressure/(needle constant x relative viscosity). Thus, CSF flow rate during lumbar puncture can be used to estimate CSF pressure. Because the viscosity of CSF is approximately the same as that of normal saline, 0.9% NaCl was used to model CSF flow in vitro. Flow of saline through various spinal needles was measured as pressure and temperature were varied to determine needle constants and variation in viscosity with temperature. Counting periods
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