Relevant bibliographies by topics / COX1

Contents

  1. Journal articles
  2. Dissertations / Theses
  3. Books
  4. Book chapters
  5. Conference papers
  6. Reports

Academic literature on the topic 'COX1'

Author: Grafiati
Published: 4 June 2021
Last updated: 25 July 2025

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Journal articles on the topic "COX1"

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Khalimonchuk, Oleh, Megan Bestwick, Brigitte Meunier, Talina C. Watts, and Dennis R. Winge. "Formation of the Redox Cofactor Centers during Cox1 Maturation in Yeast Cytochrome Oxidase." Molecular and Cellular Biology 30, no. 4 (2009): 1004–17. http://dx.doi.org/10.1128/mcb.00640-09.

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ABSTRACT The biogenesis of cytochrome c oxidase initiates with synthesis and maturation of the mitochondrion-encoded Cox1 subunit prior to the addition of other subunits. Cox1 contains redox cofactors, including the low-spin heme a center and the heterobimetallic heme a 3:CuB center. We sought to identify the step in the maturation of Cox1 in which the redox cofactor centers are assembled. Newly synthesized Cox1 is incorporated within one early assembly intermediate containing Mss51 in Saccharomyces cerevisiae. Subsequent Cox1 maturation involves the progression to downstream assembly intermed
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Mick, David U., Milena Vukotic, Heike Piechura, et al. "Coa3 and Cox14 are essential for negative feedback regulation of COX1 translation in mitochondria." Journal of Cell Biology 191, no. 1 (2010): 141–54. http://dx.doi.org/10.1083/jcb.201007026.

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Regulation of eukaryotic cytochrome oxidase assembly occurs at the level of Cox1 translation, its central mitochondria-encoded subunit. Translation of COX1 messenger RNA is coupled to complex assembly in a negative feedback loop: the translational activator Mss51 is thought to be sequestered to assembly intermediates, rendering it incompetent to promote translation. In this study, we identify Coa3 (cytochrome oxidase assembly factor 3; Yjl062w-A), a novel regulator of mitochondrial COX1 translation and cytochrome oxidase assembly. We show that Coa3 and Cox14 form assembly intermediates with ne
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Mohammad Fathul Qorib. "Dinamika Ekspresi Cox1 dan Cox2 Sebagai Landasan Tatalaksana Nyeri dan Inflamasi." Unram Medical Journal 11, no. 4 (2022): 1233–39. http://dx.doi.org/10.29303/jku.v11i4.868.

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Siklooksigenase (COX) merupakan enzim yang sangat penting dalam menjaga homeostasis organ tubuh manusia. Enzim ini berperan pada kondisi fisiologis dan patologis khususnya saat terjadi inflamasi. Enzim ini memiliki 3 isoform yaitu Cox1, Cox2, dan Cox3. Isoform yang banyak diteliti dan terbukti sangat berperan dalam tubuh manusia adalah Cox1 dan Cox2, sedangkan Cox3 masih banyak perbedaan pendapat. Ekpresi Cox1 dan Cox2 dapat ditemukan pada berbagai organ dalam tubuh manusia, akan tetapi dalam naskah ini akan dibatasi pembahasannya pada lambung, ginjal, saraf, kardiovaskular, dan platelet. Hal
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Pierrel, Fabien, Oleh Khalimonchuk, Paul A. Cobine, Megan Bestwick, and Dennis R. Winge. "Coa2 Is an Assembly Factor for Yeast Cytochrome c Oxidase Biogenesis That Facilitates the Maturation of Cox1." Molecular and Cellular Biology 28, no. 16 (2008): 4927–39. http://dx.doi.org/10.1128/mcb.00057-08.

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ABSTRACT The assembly of cytochrome c oxidase (CcO) in yeast mitochondria is dependent on a new assembly factor designated Coa2. Coa2 was identified from its ability to suppress the respiratory deficiency of coa1Δ and shy1Δ cells. Coa1 and Shy1 function at an early step in maturation of the Cox1 subunit of CcO. Coa2 functions downstream of the Mss51-Coa1 step in Cox1 maturation and likely concurrent with the Shy1-related heme a 3 insertion into Cox1. Coa2 interacts with Shy1. Cells lacking Coa2 show a rapid degradation of newly synthesized Cox1. Rapid Cox1 proteolysis also occurs in shy1Δ cell
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Zambrano, Andrea, Flavia Fontanesi, Asun Solans, et al. "Aberrant Translation of CytochromecOxidase Subunit 1 mRNA Species in the Absence of Mss51p in the YeastSaccharomyces cerevisiae." Molecular Biology of the Cell 18, no. 2 (2007): 523–35. http://dx.doi.org/10.1091/mbc.e06-09-0803.

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Expression of yeast mitochondrial genes depends on specific translational activators acting on the 5′-untranslated region of their target mRNAs. Mss51p is a translational factor for cytochrome c oxidase subunit 1 (COX1) mRNA and a key player in down-regulating Cox1p expression when subunits with which it normally interacts are not available. Mss51p probably acts on the 5′-untranslated region of COX1 mRNA to initiate translation and on the coding sequence itself to facilitate elongation. Mss51p binds newly synthesized Cox1p, an interaction that could be necessary for translation. To gain insigh
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Roloff, Gabrielle A., and Michael F. Henry. "Mam33 promotes cytochromecoxidase subunit I translation inSaccharomyces cerevisiaemitochondria." Molecular Biology of the Cell 26, no. 16 (2015): 2885–94. http://dx.doi.org/10.1091/mbc.e15-04-0222.

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Three mitochondrial DNA–encoded proteins, Cox1, Cox2, and Cox3, comprise the core of the cytochrome c oxidase complex. Gene-specific translational activators ensure that these respiratory chain subunits are synthesized at the correct location and in stoichiometric ratios to prevent unassembled protein products from generating free oxygen radicals. In the yeast Saccharomyces cerevisiae, the nuclear-encoded proteins Mss51 and Pet309 specifically activate mitochondrial translation of the largest subunit, Cox1. Here we report that Mam33 is a third COX1 translational activator in yeast mitochondria
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Bestwick, Megan, Oleh Khalimonchuk, Fabien Pierrel, and Dennis R. Winge. "The Role of Coa2 in Hemylation of Yeast Cox1 Revealed by Its Genetic Interaction with Cox10." Molecular and Cellular Biology 30, no. 1 (2009): 172–85. http://dx.doi.org/10.1128/mcb.00869-09.

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ABSTRACT Saccharomyces cerevisiae cells lacking the cytochrome c oxidase (CcO) assembly factor Coa2 are impaired in Cox1 maturation and exhibit a rapid degradation of newly synthesized Cox1. The respiratory deficiency of coa2Δ cells is suppressed either by the presence of a mutant allele of the Cox10 farnesyl transferase involved in heme a biosynthesis or through impaired proteolysis by the disruption of the mitochondrial Oma1 protease. Cox10 with an N196K substitution functions as a robust gain-of-function suppressor of the respiratory deficiency of coa2Δ cells but lacks suppressor activity f
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Mitchell, Jane A., Fisnik Shala, Youssef Elghazouli, et al. "Cell-Specific Gene Deletion Reveals the Antithrombotic Function of COX1 and Explains the Vascular COX1/Prostacyclin Paradox." Circulation Research 125, no. 9 (2019): 847–54. http://dx.doi.org/10.1161/circresaha.119.314927.

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Rationale: Endothelial cells (ECs) and platelets, which respectively produce antithrombotic prostacyclin and prothrombotic thromboxane A 2 , both express COX1 (cyclooxygenase1). Consequently, there has been no way to delineate any antithrombotic role for COX1-derived prostacyclin from the prothrombotic effects of platelet COX1. By contrast, an antithrombotic role for COX2, which is absent in platelets, is straightforward to demonstrate. This has resulted in an incomplete understanding of the relative importance of COX1 versus COX2 in prostacyclin production and antithrombotic protection in viv
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Perez-Martinez, Xochitl, Christine A. Butler, Miguel Shingu-Vazquez, and Thomas D. Fox. "Dual Functions of Mss51 Couple Synthesis of Cox1 to Assembly of Cytochrome c Oxidase in Saccharomyces cerevisiae Mitochondria." Molecular Biology of the Cell 20, no. 20 (2009): 4371–80. http://dx.doi.org/10.1091/mbc.e09-06-0522.

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Functional interactions of the translational activator Mss51 with both the mitochondrially encoded COX1 mRNA 5′-untranslated region and with newly synthesized unassembled Cox1 protein suggest that it has a key role in coupling Cox1 synthesis with assembly of cytochrome c oxidase. Mss51 is present at levels that are near rate limiting for expression of a reporter gene inserted at COX1 in mitochondrial DNA, and a substantial fraction of Mss51 is associated with Cox1 protein in assembly intermediates. Thus, sequestration of Mss51 in assembly intermediates could limit Cox1 synthesis in wild type,
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Vanišová, M., D. Burská, J. Křížová, et al. "Stable COX17 Downregulation Leads to Alterations in Mitochondrial Ultrastructure, Decreased Copper Content and Impaired Cytochrome c Oxidase Biogenesis in HEK293 Cells." Folia Biologica 65, no. 4 (2019): 181–87. http://dx.doi.org/10.14712/fb2019065040181.

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Cox17 is an assembly factor that participates in early cytochrome c oxidase (COX, CcO) assembly stages. Cox17 shuttles copper ions from the cytosol to the mitochondria and, together with Sco1 and Sco2, provides copper ions to the Cox1 and Cox2 mitochondrially encoded subunits. In Saccharomyces cerevisiae, Cox17 also modulates mitochondrial membrane architecture due to the interaction of Cox17 with proteins of the MICOS complex (mitochondrial contact site and cristae organizing system). There is currently no data regarding the impact of long-term Cox17 deficiency in human cells. Here, we presen
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Dissertations / Theses on the topic "COX1"

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Silva, Fabio Nauer da. "Filogenia molecular e diversidade do gênero Hypnea (Gigartinales, Rhodophyta) na costa brasileira." Universidade de São Paulo, 2013. http://www.teses.usp.br/teses/disponiveis/41/41132/tde-25032014-180135/.

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O presente trabalho utiliza marcadores moleculares para auxiliar na caracterização e filogenia das espécies de macroalgas vermelhas do gênero Hypnea na costa do Brasil. O gênero Hypnea Lamouroux (1813) apresenta cerca de 67 espécies descritas e possui distribuição geográfica em águas quentes ao redor do mundo. Além disso, o gênero possui grande importância econômica e ecológica, como fonte de alimento e produção industrial de carragenana. Porém, a identificação das espécies de Hypnea com base exclusivamente em dados morfológicos é dificultada em virtude da plasticidade fenotípica presente no g
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Morais, Sirlei Antunes de. "Relações morfométricas e genética populacional de Culex quinquefasciatus (Diptera: Culicidae)." Universidade de São Paulo, 2011. http://www.teses.usp.br/teses/disponiveis/6/6132/tde-04032011-164328/.

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Objetivo. Culex (Culex) quinquefasciatus Say 1823 tem distribuição expansiva em aglomerados humanos e é vetor em ciclos de transmissão de agentes patogênicos, como filarídeos e arbovírus. Taxonomicamente, essa espécie está dentro do subgrupo pipiens, cuja principal característica é a similaridade morfológica dos seus integrantes. Este estudo objetivou caracterizar genética e morfologicamente espécies Cx. quinquefasciatus de dez localidades brasileiras e da região da bacia do Prata, na Argentina. Métodos. Para análises morfológicas foram utilizados valores morfométricos das veias alares de fême
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Guimarães, Natália Rodrigues. "Diversidade do gênero Hypnea (Gigartinales, Rhodophyta) do estado de São Paulo baseada em marcadores moleculares e morfologia." Universidade de São Paulo, 2011. http://www.teses.usp.br/teses/disponiveis/41/41132/tde-19012012-151152/.

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O gênero Hypnea J.V. Lamouroux (1813) (Cystocloniaceae, Gigartinales), com cerca de 67 espécies descritas, apresenta ampla distribuição geográfica pelas costas marinhas de águas quentes ao redor do mundo. Algumas espécies de Hypnea são usadas para a produção de carragenanas, hidrocolóides de grande importância na indústria atual. A taxonomia do gênero é bastante problemática e a identificação das espécies é complicada devido a uma morfologia relativamente simples que muitas vezes é influenciada pelas condições do habitat onde se encontram. Apesar das revisões regionais já realizadas, o número
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Soto, Iliana C. "Insights into the Roles of Mss51 in the Biogenesis of Mitochondrial Cox1." Scholarly Repository, 2012. http://scholarlyrepository.miami.edu/oa_dissertations/707.

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In eukaryotic cells, energy is produced by the coordinated action of the mitochondrial respiratory chain (MRC) and the oxidative phosphorylation system (OXPHOS). Cytochrome c oxidase (COX) is the fourth enzyme of the MRC. COX catalytic activity is mediated by prosthetic groups located in subunits 1 (Cox1) and 2. More than twenty nuclear encoded factors are required for the assembly of the functional enzyme. Cox1 is the center of a regulatory mechanism in which its protein levels depend on the availability of its assembly partners. A key element in the regulatory pathway is the nuclear encoded
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Agostinho, Douglas de Castro [UNESP]. "Revisão da seção Virescentia do gênero Batrachospermum (Rhodophyta, Batrachospermales)." Universidade Estadual Paulista (UNESP), 2017. http://hdl.handle.net/11449/148969.

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Submitted by DOUGLAS DE CASTRO AGOSTINHO null (douglas_c_agostinho@hotmail.com) on 2017-03-07T20:51:41Z No. of bitstreams: 1 tese (final).pdf: 2822739 bytes, checksum: 990e18e900efd974bfd4b2cd1d404619 (MD5)<br>Approved for entry into archive by Juliano Benedito Ferreira (julianoferreira@reitoria.unesp.br) on 2017-03-10T19:08:02Z (GMT) No. of bitstreams: 1 agostinho_dc_dr_sjrp.pdf: 2822739 bytes, checksum: 990e18e900efd974bfd4b2cd1d404619 (MD5)<br>Made available in DSpace on 2017-03-10T19:08:02Z (GMT). No. of bitstreams: 1 agostinho_dc_dr_sjrp.pdf: 2822739 bytes, checksum: 990e18e900efd974b
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Medeiros, Amanda da Silva. "Diversidade de macroalgas da Baía do Almirantado, ilha Rei George, Península Antártica, baseada em 'DNA barcoding' e outros marcadores moleculares." Universidade de São Paulo, 2013. http://www.teses.usp.br/teses/disponiveis/41/41132/tde-24032014-090801/.

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Baseado em estudos morfológicos, as macroalgas marinhas da Baía do Almirantado (Ilha Rei George, Península Antártica) estão representadas por 55 táxons, sendo 30 Rhodophyta, 16 Phaeophyceae e 9 Chlorophyta. Recentemente foi proposta a utilização de &#39;DNA barcode&#39; para uma rápida e acurada identificação de espécies de macroalgas. Sendo a região 5\' do gene mitocondrial cox 1utilizado para identificação de algas vermelhas e pardas; o gene plastidial tufA utilizado na identificação de algas verdes; e o domínio V do gene 23S rRNA - UPA, universal plastid amplicon, utilizado na identificação
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Santos, Tânia Raquel Martins dos. "Genetic characterization of Portuguese Fasciola hepatica isolates." Master's thesis, Faculdade de Ciências e Tecnologia, 2012. http://hdl.handle.net/10362/8689.

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Dissertation presented to obtain the Master Degree in Molecular, Genetics and Biomedicine<br>Part of the results discussed in this dissertation was presented in the following communications: R. Santos, M. Calado, J. Sampaio, C. Ferreira, A. Afonso and S. Belo. Contribution to the genetic characterization of Fasciola hepatica populations in Portugal. XXXVII Portuguese Genetic Conference, Lisbon, Portugal, May 28th-30th 2012 [poster communication] R. Santos, M. Calado, J. Sampaio, C. Ferreira, A. Afonso and S. Belo. Contribution to the genetic characterization of Fasciola hepatica populations
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Johnston, Anne. "Evolutionary Relationships Among Duiker Antelope (Bovidae: Cephalophinae)." ScholarWorks@UNO, 2011. http://scholarworks.uno.edu/td/1401.

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Duikers are a species rich subfamily of threatened African antelope whose recent origin poses a challenge to the molecular identification of taxa and estimation of their phylogeny. I test the ability of DNA barcodes to identify all taxa within this group. I then use mitochondrial and nuclear genes to estimate a multi-locus species tree and to date divergence times. DNA barcodes are unable to distinguish many sister taxa, calling into question the utility of barcodes for the regulation of duiker trade or in identification of field-collected feces. The multi-locus phylogeny provides support for
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Saeb, Amr. "Phylogenetic and population genetic studies on some insect and plant associated nematodes." The Ohio State University, 2006. http://rave.ohiolink.edu/etdc/view?acc_num=osu1158348092.

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Kowalewski, Mariusz Paweł. "Untersuchungen zur Rolle des Prostaglandin Systems in der Regulation der Corpus Luteum Funktion der Hündin durch Erfassung der Expression von Cyclooxygenase 1 und -2 (Cox1,-2), Prostaglandin F2alpha Synthase (PGFS), Prostaglandin E2 Synthase (PGES) und Prostaglandin F2alpha Rezeptor (PGFR)." Lollar : Rosenbaum, 2007. http://geb.uni-giessen.de/geb/volltexte/2007/4476/index.html.

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Books on the topic "COX1"

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Lace, Kate. Cox. CArrow, 2012.

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Cox, Avis E. From the banks of the Dan: A Cox family genealogy. A.E. Cox, 1994.

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(Firm), Cox &. Power. Cox & Power. Cox & Power, 1995.

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Franck, Mallet, ed. Paul Cox. Pyramyd, 2003.

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Copyright Paperback Collection (Library of Congress), ed. Elaine Cox. Blue Moon, 2001.

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Gallery, Tate, ed. Stephen Cox. Tate Gallery Publications, 1986.

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Chetwin, Grace. Box and Cox. Bradbury Press, 1990.

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Pairet, Michel, and Joanne van Ryn, eds. COX-2 Inhibitors. Birkhäuser Basel, 2004. http://dx.doi.org/10.1007/978-3-0348-7879-1.

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Warner, Yvonne Story. The family Cox. Y.S. Warner, 1987.

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Stephen, Cox. Stephen Cox: Scultura. Galleria Carini, 1987.

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Book chapters on the topic "COX1"

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Tu, My, Karina Gritsenko, Boleslav Kosharskyy, and Naum Shaparin. "Antipyretics: Acetaminophen, Arachidonic Acid Agents, and COX1 and COX2 Inhibitors." In Essentials of Pharmacology for Anesthesia, Pain Medicine, and Critical Care. Springer New York, 2014. http://dx.doi.org/10.1007/978-1-4614-8948-1_27.

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Beyhan, Yunus Emre. "Cystic Echinococcosis and Molecular Diagnosis." In Molecular Approaches in Medicine. Nobel Tip Kitabevleri, 2024. http://dx.doi.org/10.69860/nobel.9786053359524.1.

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Cystic echinococcosis (CE) is a parasitic disease caused by the larval form of Echinococcus granulosus. It predominantly affects the liver but can also impact the lungs, kidneys, spleen, brain, bones, and heart. CE is prevalent in regions with low socio-economic status and is associated with significant health and economic burdens due to medical costs and reduced livestock productivity. Diagnosis typically involves radiological and serological methods, and treatment primarily consists of surgery, though drug therapy and less invasive procedures like PAIR are also used. Prevention focuses on co
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Gabrys, Beata, John L. Capinera, Jesusa C. Legaspi, et al. "Coxa." In Encyclopedia of Entomology. Springer Netherlands, 2008. http://dx.doi.org/10.1007/978-1-4020-6359-6_10063.

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Dixon, D. A. "Regulation of COX-2 Expression in Human Cancers." In COX-2. KARGER, 2003. http://dx.doi.org/10.1159/000071363.

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Baron, J. A. "Epidemiology of Non-Steroidal Anti-Inflammatory Drugs and Cancer." In COX-2. KARGER, 2003. http://dx.doi.org/10.1159/000071364.

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Isakson, P. C. "Pharmacology of COX-2 Inhibitors." In COX-2. KARGER, 2003. http://dx.doi.org/10.1159/000071366.

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F�rstenberger, G., F. Marks, and K. M�ller-Decker. "Cyclooxygenase-2 and Skin Carcinogenesis." In COX-2. KARGER, 2003. http://dx.doi.org/10.1159/000071367.

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Dannenberg, A. J., and L. R. Howe. "The Role of COX-2 in Breast and Cervical Cancer." In COX-2. KARGER, 2003. http://dx.doi.org/10.1159/000071368.

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Altorki, N. K., K. Subbaramaiah, and A. J. Dannenberg. "Cyclooxygenase-2: A Target for the Prevention and Treatment of Cancers of the Upper Digestive Tract." In COX-2. KARGER, 2003. http://dx.doi.org/10.1159/000071369.

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DuBois, R. N. "Cyclooxygenase-2 and Colorectal Cancer." In COX-2. KARGER, 2003. http://dx.doi.org/10.1159/000071370.

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Conference papers on the topic "COX1"

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Maderankova, Denisa, and Ivo Provaznik. "Motive representation in nucleotide densities of bird's mitochondrial gene COX1." In the 4th International Symposium. ACM Press, 2011. http://dx.doi.org/10.1145/2093698.2093739.

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Lobanova, V. V., B. E. Efimenko, and K. Yu Popadin. "USING BARCODING DATA TO ANALYZE THE MUTAGENESIS OF NEMATODE MITOCHONDRIAL DNA." In OpenBio-2023. ИПЦ НГУ, 2023. http://dx.doi.org/10.25205/978-5-4437-1526-1-25.

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The Nematoda phylum is a promising group for studying the relationship between ecological and genetic characteristics, but the number of high-quality sequences, including mtDNA, is small. In this work, the possibility of increasing the database for these aims by using barcoding data (COX1) was considered, possible problems and their significance for mtDNA mutagenesis analyses were identified.
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Koshel, A. A., G. G. Osadchiy, A. A. Mikhailova, et al. "DIFFERENCES IN THE MTDNA MUTATION SPECTRUM OF TERMITE AND NON-TERMITE COCKROACHES ARE ASSOCIATED WITH LIFE EXPECTANCY." In OpenBio-2023. ИПЦ НГУ, 2023. http://dx.doi.org/10.25205/978-5-4437-1526-1-23.

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We analyzed the mutational spectra of the COX1 gene for 16 species of termite cockroaches and 7 species of non-termite cockroaches using phylogenetic methods and found that social termites have more frequent Ah &gt; Gh substitutions compared to less social termites and cockroaches, which may indicate the influence of life expectancy on the mutational spectrum of mtDNA.
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Ziołkowska, Kaja, Paweł Grychnik, Krzysztof Kowal, Angelika Tkaczyk-Wlizło, and Brygida Ślaska. "Mutations and polymorphisms in COX1 gene and D-loop region in dogs with solid mammary carcinoma." In 3rd International PhD Student’s Conference at the University of Life Sciences in Lublin, Poland: ENVIRONMENT – PLANT – ANIMAL – PRODUCT. Publishing House of The University of Life Sciences in Lublin, 2024. http://dx.doi.org/10.24326/icdsupl3.a031.

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Zhang, Tianshun, Qiushi Wang, Wei-Ya Ma, et al. "Abstract 2593: Inhibition of COX1/2-driven thromboxane A2 pathway suppresses Barrett's esophagus and esophageal adenocarcinoma development." In Proceedings: AACR Annual Meeting 2020; April 27-28, 2020 and June 22-24, 2020; Philadelphia, PA. American Association for Cancer Research, 2020. http://dx.doi.org/10.1158/1538-7445.am2020-2593.

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G. V., Izotova, Vlasenko P. G., Kashinskaya E. N., and Solovyev M. M. "IDENTIFICATION OF DIPLOSTOMOSIS PATHOGENS OF PREDOMINATING FISH SPECIES OF SIBERIA USING DNA-BARCODING APPROACH." In II INTERNATIONAL SCIENTIFIC AND PRACTICAL CONFERENCE "DEVELOPMENT AND MODERN PROBLEMS OF AQUACULTURE" ("AQUACULTURE 2022" CONFERENCE). DSTU-Print, 2022. http://dx.doi.org/10.23947/aquaculture.2022.53-55.

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Metacercariae of the genus Diplostomum are localized in the eyes and the brain of freshwater fish and cyclostomata species causing different types of diplostomosis. Hyperinvasion by these parasites lead to spatial disorientation, changing in feeding activity, lowering the growth rate, etc. Species identification of Diplostomum spp. based on the morphological features is difficult due to the lack and severity of them. In present study, species diversity of the genus Diplostomum metacercariae parasitizing in fishes of Chany, Baunt and Teletskoye lakes is defined according to the DNA-barcoding ap
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Keta, Otilija, Jelena Bošković, Vladana Petković, et al. "Synthesis and cytotoxic activity of selected dual COX-2 and 5-LOX inhibitors in HeLa and MIA PaCa-2 human cancer cell lines." In 2nd International Conference on Chemo and Bioinformatics. Institute for Information Technologies, University of Kragujevac, 2023. http://dx.doi.org/10.46793/iccbi23.503k.

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Among novel cancer chemotherapy approaches, the use of cyclooxygenases (COXs) and lipoxygenases (LOXs) inhibitors represents a promising mean for cancer treatment showing lesser toxicity comparing to the currently used cytotoxic drugs. This study detailed the synthesis of three novel compounds: 1ME, BHTK-AA, and IBU-Ac, each with the capability to concurrently inhibit both COX-2 and 5-LOX. Subsequently, we assessed their effectiveness in inhibiting the proliferation of HeLa cervical and MIA PaCa-2 pancreatic cancer cells. The IC50 values for both examined cell lines were approximately 40 μM, i
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Giordano, Antonio, Miquel Urpí, Gherzon Casanova, et al. "COMPARACION DE LA CÁPSULA ENDOSCÓPICA CON INTELIGENCIA ARTIFICAL NAVICAM CON LA CÁPSULA ENDOSCÓPICA CONVENCIONAL PILLCAM SB3 EN LA EXPLORACION DE INTESTINO DELGADO: ESTUDIO PILOTO NAVIPILL." In 44 Congreso de la Sociedad Española de Endoscopia Digestiva. Grupo Pacífico, 2022. http://dx.doi.org/10.48158/seed2022.co31.

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Espinet, Eduardo, Andrés J. del Pozo, Román Turró, et al. "Estudio multicéntrico de seguridad del balón intragástrico en todas sus modalidades. Encuesta Nacional de Balón Intragástrico (Gettemo-SEED’22)." In 44 Congreso de la Sociedad Española de Endoscopia Digestiva. Grupo Pacífico, 2022. http://dx.doi.org/10.48158/seed2022.co21.

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Albéniz, Eduardo, Alberto Herreros de Tejada, Felipe Ramos-Zabala, et al. "Validación del score coreano de hemorragia diferida tras DSE y creación de un nuevo modelo predictivo del GSEED-RE." In 44 Congreso de la Sociedad Española de Endoscopia Digestiva. Grupo Pacífico, 2022. http://dx.doi.org/10.48158/seed2022.co11.

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Reports on the topic "COX1"

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Santi, Peter Angelo. COE1 Calorimeter Operations Manual. Office of Scientific and Technical Information (OSTI), 2015. http://dx.doi.org/10.2172/1233249.

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Levine, Alice C. COX-2 and Prostate Cancer Angiogenesis. Defense Technical Information Center, 2002. http://dx.doi.org/10.21236/ada405593.

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Levine, Alice C. COX-2 and Prostate Cancer Angiogenesis. Defense Technical Information Center, 2003. http://dx.doi.org/10.21236/ada420162.

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Reddy, E. P. Novel COX-2 Inhibitor for Breast Cancer Therapy. Defense Technical Information Center, 2005. http://dx.doi.org/10.21236/ada444637.

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Reddy, E. P. Novel Cox-2 Inhibitor for Breast Cancer Therapy. Defense Technical Information Center, 2004. http://dx.doi.org/10.21236/ada431390.

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Reddy, E. P. Novel COX-2 Inhibitor for Breast Cancer Therapy. Defense Technical Information Center, 2003. http://dx.doi.org/10.21236/ada420352.

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Fields, Michael J., Mordechai Shemesh, and Anna-Riitta Fuchs. Significance of Oxytocin and Oxytocin Receptors in Bovine Pregnancy. United States Department of Agriculture, 1994. http://dx.doi.org/10.32747/1994.7568790.bard.

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Oxytocin has multiple actions in bovine reproductive tract and it was our purpose to determine the nature of these actions and their significance for the physiology of bovine reproduction. The bovine oxytocin receptors (OTR) gene was cloned and its expression studied during the cycle and pregnancy. OTR mRNA changed in parallel with OTR with control occurring mainly at the transcriptional level. However, the endocrine regulation of OTR were found in endometrium and cervical mucosa at estrus and at parturition. In both tissues OTR were suppressed in the luteal phase and early pregnancy. Whereas
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Martín Sanz, Paloma. Papel dual de Cox-2 en la fisiopatología hepática. Sociedad Española de Bioquímica y Biología Molecular, 2016. http://dx.doi.org/10.18567/sebbmdiv_anc.2016.04.1.

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Burr, Deborah. A Study of Bootstrap Confidence Intervals in a Cox Model. Defense Technical Information Center, 1992. http://dx.doi.org/10.21236/ada254598.

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Karr, Alan F. State Estimation for Cox Processes with Unknown Law: Parametric Models. Defense Technical Information Center, 1985. http://dx.doi.org/10.21236/ada166179.

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