Relevant bibliographies by topics / Coxib

Contents

  1. Journal articles
  2. Dissertations / Theses
  3. Books
  4. Book chapters
  5. Conference papers
  6. Reports

Academic literature on the topic 'Coxib'

Author: Grafiati
Published: 4 June 2021
Last updated: 25 July 2025

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Journal articles on the topic "Coxib"

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Vio, Carlos P., Mariana Quiroz-Munoz, Catherina A. Cuevas, Carlos Cespedes, and Nicholas R. Ferreri. "Prostaglandin E2 EP3 receptor regulates cyclooxygenase-2 expression in the kidney." American Journal of Physiology-Renal Physiology 303, no. 3 (2012): F449—F457. http://dx.doi.org/10.1152/ajprenal.00634.2011.

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Cyclooxygenase-2 (COX-2) is constitutively expressed and highly regulated in the thick ascending limb (TAL). As COX-2 inhibitors (Coxibs) increase COX-2 expression, we tested the hypothesis that a negative feedback mechanism involving PGE2 EP3 receptors regulates COX-2 expression in the TAL. Sprague-Dawley rats were treated with a Coxib [celecoxib (20 mg·kg−1·day−1) or rofecoxib (10 mg·kg−1·day−1)], with or without sulprostone (20 μg·kg−1·day−1). Sulprostone was given using two protocols, namely, previous to Coxib treatment (prevention effect; Sulp7-Coxib5 group) and 5 days after initiation of
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Gross, Manfred. "NSAR, Coxibe und Steroide: Wann und wie sollten Magen und Darm geschützt werden?" Aktuelle Rheumatologie 42, no. 06 (2017): 497–504. http://dx.doi.org/10.1055/s-0043-110009.

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ZusammenfassungNicht-steroidale Antirheumatika (NSAR) haben ein hohes Risiko für gastrointestinale Komplikationen wie Ulzera, Ulkusblutungen oder Perforationen. Zudem verspüren 25-30% der Patienten Oberbauchbeschwerden (Dyspepsie). Die PPI-Komedikation zu einem NSAR kann die Rate an Ulzera, Blutungen und sonstigen Komplikationen sowie die Dyspepsierate senken. Ein anderer Ansatz zur Erhöhung der Sicherheit der Therapie ist die Verschreibung eines Cox-2-spezifischen NSAR (Coxib). Unter Coxiben treten seltener gastrointestinale Komplikationen einer NSAR-Therapie auf.Die beiden präventiven Strate
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Hunt, Richard H., Alan N. Barkun, David Baron, et al. "Recommendations for the Appropriate Use of Anti-Inflammatory Drugs in the Era of the Coxibs: Defining the Role of Gastroprotective Agents." Canadian Journal of Gastroenterology 16, no. 4 (2002): 231–40. http://dx.doi.org/10.1155/2002/516092.

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Treatment with anti-inflammatory drugs and the analgesic efficacy of conventional nonsteroidal anti-inflammatory drugs (NSAIDs) are compromised by a two- to fourfold increased risk of gastrointestinal complications. This increased risk has resulted in an increasing use of the new selective cyclooxygenase-2 inhibitors or coxibs, which, in clinical trials and outcomes studies, reduced gastrointestinal adverse events by 50% to 65% compared with conventional NSAIDs. However, the coxibs are not available to all patients who need them, and NSAIDs are still widely used. Moreover, treatment with a cox
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Yan, Brian, Yvette Leung, Stefan J. Urbanski, and Robert P. Myers. "Rofecoxib-Induced Hepatotoxicity: A Forgotten Complication of the Coxibs." Canadian Journal of Gastroenterology 20, no. 5 (2006): 351–55. http://dx.doi.org/10.1155/2006/356434.

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Rofecoxib is a member of the coxib family of nonsteroidal anti-inflammatory drugs that selectively inhibit cyclooxygenase-2. Although the coxibs are generally well-tolerated, rofecoxib was recently withdrawn from the market due to concerns regarding cardiovascular safety. Rare cases of hepatic injury attributable to the coxibs have been reported. In the present study, two additional cases of severe hepatotoxicity are described in patients with cholestatic symptoms and abnormal liver biochemistry, shortly following the initiation of rofecoxib for arthritic complaints. In both cases, liver histo
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Ghosh, Mallika, Haibin Wang, Youxi Ai та ін. "COX-2 suppresses tissue factor expression via endocannabinoid-directed PPARδ activation". Journal of Experimental Medicine 204, № 9 (2007): 2053–61. http://dx.doi.org/10.1084/jem.20070828.

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Although cyclooxygenase (COX)-2 inhibitors (coxibs) are effective in controlling inflammation, pain, and tumorigenesis, their use is limited by the recent revelation of increased adverse cardiovascular events. The mechanistic basis of this side effect is not well understood. We show that the metabolism of endocannabinoids by the endothelial cell COX-2 coupled to the prostacyclin (PGI2) synthase (PGIS) activates the nuclear receptor peroxisomal proliferator–activated receptor (PPAR) δ, which negatively regulates the expression of tissue factor (TF), the primary initiator of blood coagulation. C
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Dembo, Gregory, Sang B. Park, and Evan D. Kharasch. "Central Nervous System Concentrations of Cyclooxygenase-2 Inhibitors in Humans." Anesthesiology 102, no. 2 (2005): 409–15. http://dx.doi.org/10.1097/00000542-200502000-00026.

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Background Cyclooxygenase-2 (COX-2)-selective inhibitors (coxibs) are under investigation for the potential therapy, attenuation, or prevention of neuroinflammatory and neurodegenerative disorders. Coxibs are also a significant advance in pain therapy and are traditionally considered to achieve analgesia via peripheral effects. However, in animals, central nervous system (CNS) COX-2 activity and prostanoid concentrations are increased by peripheral inflammation, central sensitization has been proposed to account for long-term pain-related phenomena, and coxibs achieve significant cerebrospinal
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Ribaldone, Davide Giuseppe. "Coxib Safety in Patients with Inflammatory Bowel Diseases: A Meta-analysis." Pain Physician 6;18, no. 6;11 (2015): 599–607. http://dx.doi.org/10.36076/ppj.2015/18/599.

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Background: Patients with inflammatory bowel diseases (IBD) frequently have extraintestinal manifestations including arthritis, sacroiliitis, and ankylosing spondylitis. While the treatment of these rheumatological conditions with traditional non-steroidal anti-inflammatory drugs (NSAIDs) has been reported to lead to frequent IBD exacerbation, the safety of cyclooxygenase-2 (COX-2) inhibitors (Coxibs) remains unclear. Objectives: Our aim is to carry out a meta-analysis to verify if Coxibs, employed to treat rheumatological manifestations, are associated with an increased risk of exacerbation o
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Whelton, Andrew. "The Coxib Conundrum." American Journal of Therapeutics 11, no. 6 (2004): 417–21. http://dx.doi.org/10.1097/01.mjt.0000149719.58535.b0.

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Schmutz, J. L., A. Barbaud, and P. Trechot. "Pseudoporphyrie et Coxib." Annales de Dermatologie et de Vénéréologie 133, no. 2 (2006): 213. http://dx.doi.org/10.1016/s0151-9638(06)70881-x.

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Seta, Francesca, Andrew D. Chung, Patricia V. Turner, Jeffrey D. Mewburn, Ying Yu, and Colin D. Funk. "Renal and cardiovascular characterization of COX-2 knockdown mice." American Journal of Physiology-Regulatory, Integrative and Comparative Physiology 296, no. 6 (2009): R1751—R1760. http://dx.doi.org/10.1152/ajpregu.90985.2008.

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Selective cyclooxygenase-2 (COX-2) inhibitors (coxibs) increase the incidence of cardiovascular and cerebrovascular events. Complete disruption of the murine gene encoding COX-2 ( Ptgs2) leads to renal developmental problems, as well as female reproductive anomalies and patent ductus arteriosus of variable penetrance in newborns, thus rendering this genetic approach difficult to compare with coxib administration. Here, we created hypomorphic Ptgs2 (COX-2Neo/Neo) mice in which COX-2 expression is suppressed to an extent similar to that achieved with coxibs, but not eliminated, in an attempt to
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Dissertations / Theses on the topic "Coxib"

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Persson, Jakob. "Which COX-inhibitor to which patient; an analysis of contemporary evidence including pharmacology and medicinal chemistry." Thesis, Linnéuniversitetet, Institutionen för kemi och biomedicin (KOB), 2018. http://urn.kb.se/resolve?urn=urn:nbn:se:lnu:diva-72226.

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NSAIDs are among the most used drugs in the world. It is estimated that 30 million people take NSAIDs daily world-wide, without including drugs sold over the counter. They are effective in alleviating pain and inflammation. Even though they are very common there does not appear to be any clear-cut guidelines to when which NSAID should be used. It has therefore been the purpose of this thesis to analyze if there is a need to differentiate between different NSAIDs according to contemporary evidence. Since the withdrawal of rofecoxib in 2004 there has been a general idea that coxibs as a group ar
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Tambuscio, Antonio. "Ruolo dei farmaci antinfiammatori e antileucotrienici nel prevenire la fibrosi capsulare periprotesica nella ricostruzione mammaria post oncologica." Doctoral thesis, Università degli studi di Padova, 2010. http://hdl.handle.net/11577/3421556.

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Capsular tissue around silicone breast implants is a normal inflammatory reaction versus a foreign body. Capsular hypertrophy and contraction is an abnormal scar reaction to the implant and it is actually the main factor causing a poor aesthetic results of mammary reconstruction after oncologic surgery. We evaluated the efficiency of new NSAD (cox2 ihnibitors - etoricoxib) and anti-leuckotriene drugs (zafirlukast) in preventing capsular contraction around silicone breast implants. A selection of women scheduled for mastectomy and immediate reconstruction with tissue expander has been raodnomi
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Hoxha, M. "THE POTENTIAL THERAPEUTIC ROLE OF MONTELUKAST AND NEW HYBRID AGENTS, TXA2 ANTAGONIST-COX-2 INHIBITORS IN CARDIOVASCULAR EVENTS." Doctoral thesis, Università degli Studi di Milano, 2016. http://hdl.handle.net/2434/347148.

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The main target of my PhD research project was to explore new alternatives to reduce the cardiovascular (CV) risk targeting the arachidonic acid metabolites. Hence, I have been part of two different projects, one studying multitarget compounds with balanced COXIB and TP receptor antagonist properties, and the other evaluating the potential role of a leukotriene (LT) antagonist drug such as montelukast in improving the CV outcome. In reference to the first project, new multitarget compounds were synthesized at the University of Turin, by substituting the carboxylic function of Lumiracoxib.
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Barbetti, Marcos Rogerio Sanches. "Estudo comparativo entre coxim hidraúlico e coxim elastomérico, aplicados ao sistema de apoio do motor automotivo." Universidade de São Paulo, 2005. http://www.teses.usp.br/teses/disponiveis/3/3149/tde-30122014-163747/.

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Devido a forte concorrência dentro do mercado automobilístico, aspectos como qualidade e custo tornam-se prioritários na busca de competitividade. Diversas empresas trabalham em propostas visando a redução de custo sem perda de qualidade. Diversos veículos dentro do mercado brasileiro usam o coxim hidráulico no sistema de apoio do motor. A proposta inicial visa substituição deste coxim por um coxim elastomérico. Seguindo esta proposta, tem-se esta pesquisa que visa apresentar comparativamente o comportamento entre o coxim hidráulico e o coxim elastomérico. Além da revisão bibliográfica, realiz
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Jones, Anna Louise. "The leading region of IncIl plasmid ColIb-P9." Thesis, University of Leicester, 1991. http://hdl.handle.net/2381/34430.

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The IncIl conjugative plasmid ColIb-P9 carries a psiB gene that prevents induction of the SOS response in host bacteria. This locus was found to be located 2.5 kb downstream of the ssb (single-stranded DNA- binding protein) gene in the leading region of ColIb. This portion of the plasmid is transferred first to the recipient cell during conjugation and is strikingly similar to part of the leading region of the otherwise distinct F plasmid. Determination of the nucleotide sequence of ColIb psiB demonstrated that the gene has 84% identity with the psiB gene of F. Promoterless lacZ fusions on Col
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Боледзюк, В. Б., та Р. Л. Поцілуйко. "Дослідження магнітних властивостей сполук CoxSb[2]Te[3]". Thesis, Сумський державний університет, 2017. http://essuir.sumdu.edu.ua/handle/123456789/64406.

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Інтеркальовані кобальтом при накладанні магнітного поля шаруваті кристали Sb2Te3 характеризуються магнітними властивостями – залежності питомого магнітного моменту отриманих інтеркалатів Co0.15Sb2Te3 мають форму петель гістерезису. Припускається, що даний факт обумовлений формуванням нановключень інтеркалянта в місцях вакансій халькогену та впливом магнітного поля на процеси обмінної взаємодії між даними нановключеннями.
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Reinauer, Christina [Verfasser], Karsten [Akademischer Betreuer] Schrör, and Peter [Akademischer Betreuer] Brenneisen. "Expression und Translation des COX1b-Gens in humanen Zellen - kein Hinweis auf die Bildung eines COX1b-Proteins / Christina Reinauer. Gutachter: Karsten Schrör ; Peter Brenneisen." Düsseldorf : Universitäts- und Landesbibliothek der Heinrich-Heine-Universität Düsseldorf, 2014. http://d-nb.info/104617424X/34.

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Roscoe, Richard Alan. "Regulation of leading region genes on IncI1 plasmid ColIb-P9." Thesis, University of Leicester, 1996. http://hdl.handle.net/2381/34468.

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The psiB and ssb genes of IncI1 plasmid ColIb-P9 reside in the leading region, which is the first portion of the plasmid to be transferred during conjugation. These genes are expressed in a transient burst in newly-formed transconjugants via a process known as zygotic induction, and are thought to promote establishment of the immigrant plasmid. One hypothesis for the regulation of zygotic induction is that the genes are activated as part of a conjugation-induced heat-shock response. Both ssb and psiB are damage-inducible and have putative sigma 32-dependent promoter sequences. Data are present
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Read, Timothy Damian. "Evasion of restriction systems by plasmid ColIb-P9 during bacterial conjugation." Thesis, University of Leicester, 1993. http://hdl.handle.net/2381/34463.

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Conjugative transmission of enterobacterial plasmid ColIb was found to be relatively resistant to type I and type II restriction systems specified by the recipient cell. One process contributing to evasion of restriction barriers during conjugation apparently involves transfer of multiple copies of the plasmid. A more specialized anti-restriction mechanism requires the product of the ColIb ard (alleviation of restriction of DNA) gene. The Ard phenotype was discovered from the ability of ColIb to alleviate EcoK (type I) restriction of unmodified infecting the plasmid-harbouring cell. Ard activi
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Howland, Christopher James. "The single-stranded DNA-binding protein gene of plasmid Colib-P9." Thesis, University of Leicester, 1989. http://hdl.handle.net/2381/34428.

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The Incil plasmid Colib-P9 was found to carry a single-stranded DNA-binding protein gene (ssb), and the cloned gene was able to suppress the UV and temperature-sensitivity of an ssb-l strain of Escherichia coli K-12. Determination of the nucleotide sequence of Colib ssb demonstrated that the gene shows considerable homology to the ssb gene of plasmid F. In contrast, Southern hybridization techniques indicated that the IncP plasmid RP4 lacks a gene with any extensive homology to F ssb. It was shown that the direction of transfer of Colib-P9 is such that the Colib ssb gene, which lies approximat
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Books on the topic "Coxib"

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Neto, João Ferreira. Raízes de Coxim. Editora UFMS, Universidade Federal de Mato Grosso do Sul, 2004.

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Keith, Floyd. Floyd on Italy: 'I came, I saw, I cooked!' 'Veni, Vidi, Coxi!'. BCA, 1994.

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Takahashi, Kazuki. Yu-Gi-Oh!. Viz, 2004.

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Takahashi, Kazuki. Yu-Gi-Oh! Shonen Jump Graphic Novel/Viz, 2004.

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Takahashi, Kazuki. Yu-Gi-Oh! Viz, 2004.

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Takahashi, Kazuki. Yu-Gi-Oh!.: Duelist kingdom. Viz LLC, 2005.

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Takahashi, Kazuki. Yu-gi-oh! VIZ, 2003.

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Takahashi, Kazuki. Yu-Gi-Oh!. Viz, 2004.

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Takahashi, Kazuki. Yu-gi-oh!. VIZ, 1996.

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Noble, Roger. Daily CoXiX. Lulu Press, Inc., 2014.

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Book chapters on the topic "Coxib"

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Graham, Garry G., and Richard O. Day. "Coxibs." In Compendium of Inflammatory Diseases. Springer Basel, 2016. http://dx.doi.org/10.1007/978-3-7643-8550-7_22.

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Graham, Garry G., and Richard O. Day. "Coxibs." In Encyclopedia of Inflammatory Diseases. Springer Basel, 2016. http://dx.doi.org/10.1007/978-3-0348-0620-6_22-2.

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Graham, Garry G., and Richard O. Day. "Coxibs." In Encyclopedia of Inflammatory Diseases. Springer Basel, 2015. http://dx.doi.org/10.1007/978-3-0348-0620-6_22-1.

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Azimova, Shakhnoza S., and Anna I. Glushenkova. "Eriostemon coxii Müller." In Lipids, Lipophilic Components and Essential Oils from Plant Sources. Springer London, 2012. http://dx.doi.org/10.1007/978-0-85729-323-7_2682.

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Laufer, Stefan A. "Coxibs and Novel Compounds, Chemistry." In Encyclopedia of Pain. Springer Berlin Heidelberg, 2013. http://dx.doi.org/10.1007/978-3-642-28753-4_920.

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Garcia Rodriguez, Luis A., Lucia Cea-Soriano, Stefania Tacconelli, and Paola Patrignani. "Coxibs: Pharmacology, Toxicity and Efficacy in Cancer Clinical Trials." In Recent Results in Cancer Research. Springer Berlin Heidelberg, 2012. http://dx.doi.org/10.1007/978-3-642-30331-9_4.

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Piazuelo, Elena, and Angel Lanas. "Clinical Effects of NSAIDs and COXIBs in Colon Cancer Prevention." In NSAIDs and Aspirin. Springer International Publishing, 2016. http://dx.doi.org/10.1007/978-3-319-33889-7_13.

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Schug, S. A. "The Role of Coxibs in the Management of Postoperative Pain." In Chronic Postsurgical Pain. Springer International Publishing, 2014. http://dx.doi.org/10.1007/978-3-319-04322-7_8.

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"Coxib." In Encyclopedia of Pain. Springer Berlin Heidelberg, 2013. http://dx.doi.org/10.1007/978-3-642-28753-4_100488.

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McQuay, Henry J., and Andrew Moore. "AINE y Coxib." In Wall y Melzack. Tratado del Dolor. Elsevier, 2007. http://dx.doi.org/10.1016/b978-84-8174-949-6.50030-7.

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Conference papers on the topic "Coxib"

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Cendrós, C. M., M. Salichs, A. K. Samp, G. Encina, J. M. Vela, and J. M. Homedes. "V08 Pharmacology of enflicoxib, a new coxib drug: dose determination by efficacy and pharmacokinetic guided approach for the treatment of osteoarthritis in dogs based on an acute arthritis induction model." In 6. Tagung der DVG-Fachgruppe Veterinärmedizinische Anästhesie, Intensivmedizin, Notfallmedizin & Schmerztherapie (VAINS). Georg Thieme Verlag KG, 2021. http://dx.doi.org/10.1055/s-0041-1739108.

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Choi, Y., K. Lee, Y. Kim, T. Kim, C. You, and M. Jung. "Oscillatory magnetic coupling in amorphous CoSiB/Pt/CoSiB structure." In 2015 IEEE International Magnetics Conference (INTERMAG). IEEE, 2015. http://dx.doi.org/10.1109/intmag.2015.7156734.

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GONZÁLEZ, SILVIA MARIA, and Dalia Damaris Pereira. "Fractura de coxis." In 31 Congreso Nacional de Medicina General y de Familia. Grupo Pacífico, 2025. https://doi.org/10.48158/semg25-843.

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Kallergis, George, Stelios Sfakianakis, Michael Zervakis, and Marios Spanakis. "Drugs with SMILES Similar to Coxibs." In 2019 IEEE 19th International Conference on Bioinformatics and Bioengineering (BIBE). IEEE, 2019. http://dx.doi.org/10.1109/bibe.2019.00153.

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Kravčák, Jozef, and Peter Vrábel. "Magnetoimpedance of soft ferromagnetic CoSiB microwire suitable for sensor applications." In APPLIED PHYSICS OF CONDENSED MATTER (APCOM2023). AIP Publishing, 2024. http://dx.doi.org/10.1063/5.0187659.

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Oliveira, Marta Francisco de, Marcos Vinicius Leite, and Milena Cruz. "ESPAÇOS DE CULTURA, MEMÓRIAS E HISTÓRIAS LOCAIS EM COXIM, MS." In Anais do Congresso Brasileiro Interdisciplinar em Ciência e Tecnologia. Even3, 2023. http://dx.doi.org/10.29327/1298891.4-159.

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Kravčák, Jozef, and Peter Vrábel. "Numerical analysis of magnetization reversal in glass-covered CoSiB microwires." In APPLIED PHYSICS OF CONDENSED MATTER (APCOM 2024). AIP Publishing, 2024. http://dx.doi.org/10.1063/5.0235172.

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Lee, Hong-Chang, Bo-Hyeon Kim, and Myung-Joon Lee. "CoLib: Client Library for Effective Development of WebDAV-based Collaborative Application." In 2011 Fifth International Conference on Innovative Mobile and Internet Services in Ubiquitous Computing (IMIS). IEEE, 2011. http://dx.doi.org/10.1109/imis.2011.122.

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Borge, A. V., and K. R. Coffey. "Investigation of GMI in CoSiB and NiFe tri-layer thin film structures." In INTERMAG Asia 2005: Digest of the IEEE International Magnetics Conference. IEEE, 2005. http://dx.doi.org/10.1109/intmag.2005.1463832.

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Wallace, Lashanale, Anju Cherian, and Felix Aikhionbare. "Abstract 2228: Differential expression of MT-ATPase and COXIV genes in colorectal adenopolyps." In Proceedings: AACR Annual Meeting 2018; April 14-18, 2018; Chicago, IL. American Association for Cancer Research, 2018. http://dx.doi.org/10.1158/1538-7445.am2018-2228.

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Reports on the topic "Coxib"

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พุทธพรทิพย์, จตุรงค์, สมชาย จงวุฒิเวศย์, สุนีย์ สีธรรมใจ та วรรณภา สุวรรณเกิด. การประยุกต์วิธีการวินิจฉัยมาลาเรียจากตัวอย่างปัสสาวะและน้ำลายเพื่อประเมินสภาวะของโรคมาลาเรียในเชิงระบาดวิทยา. จุฬาลงกรณ์มหาวิทยาลัย, 2013. https://doi.org/10.58837/chula.res.2013.17.

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การจำแนกชนิดของเชื้อมาลาเรียได้อย่างถูกต้องและการตรวจหาเชื้อมาลาเรียที่มีความไวสูงนับเป็นพื้นฐานอันสำคัญในการรักษาและควบคุมโรคมาลาเรียซึ่งเป็นโรคติดเชื้อที่สำคัญที่สุดชนิดหนึ่งของมนุษยชาติ โดยทั่วไปการวินิจฉัยโรคมาลาเรียอาศัยการตรวจหาเชื้อจากฟิล์มโลหิตที่ผ่านการย้อมสียิมซาอันทำให้การรักษาโรคเป็นไปได้อย่างมีประสิทธิภาพในเวชปฏิบัติทั่วไป อย่างไรก็ตามมีผู้ติดเชื้อมาลาเรียหลายรายที่มีปริมาณเชื้อในกระแสเลือดต่ำกว่าระดับที่สามารถตรวจพบได้ภายใต้กล้องจุลทรรศน์ ดังนั้นจึงมีผู้ติดเชื้อจำนวนมากที่ยังประสบปัญหาความเจ็บป่วยและอาจเสียชีวิตได้รวมทั้งยังเป็นการสูญเสียทางเศรษฐกิจร่วมด้วย นอกจากนี้การจำแนกชนิดข
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