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Journal articles on the topic 'CPR - cerebroplacental ratio'

Author: Grafiati

Published: 2 June 2025

Last updated: 31 July 2025

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1

Aziz, Sadaf, Pareesae Humayun, Mariam Altaf, Yasser Khan, Syed Atif Hussain Andrabi, and Mubbashrah Tahir. "Comparison of the Diagnostic Accuracy of Doppler Cerebroplacental Ratio Versus Standard Fetal Biometry for Fetal Growth Restriction." Pakistan Armed Forces Medical Journal 73, no. 2 (2023): 414–17. http://dx.doi.org/10.51253/pafmj.v73i2.8389.

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Objective: To assess the diagnostic accuracy of the Doppler Cerebroplacental ratio for fetal growth restriction keeping fetal biometry as the reference standard. Study Design: Cross-sectional study. Place and Duration of Study: Department of Radiology, Combined Military Hospital, Multan Pakistan, from May to Oct 2020. Methodology: Two hundred and fifty-six-singleton pregnancies ≥ 30 weeks were included and underwent fetal biometry, including estimated fetal weight (EFW) by trans-abdominal ultrasound. The umbilical artery and middle cerebral artery resistive indices were evalu

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Singh, Anita, Shaheen LNU, Imam Bano, and Ibne Ahmad. "Doppler Cerebroplacental Ratio and Adverse Perinatal Outcome." Journal of South Asian Federation of Obstetrics and Gynaecology 6, no. 1 (2014): 25–27. http://dx.doi.org/10.5005/jp-journals-10006-1262.

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ABSTRACT Objective This study was done to assess the Doppler cerebroplacental ratio (CPR) in the prediction of adverse perinatal outcome especially in growth restricted pregnancies. Materials and methods In this study, 62 antenatal women were subjected to Doppler studies at 34 to 42 weeks of gestations. CPR was calculated and less than 1 was taken as predictor of adverse perinatal outcome. Adverse perinatal outcomes was evaluated by mode of delivery, meconium staining, 1 and 5-minute Apgar scores, birth weight, admission to NICU and other neonatal complications. Results Of 62 antenatal women,

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International, Journal of Medical Science and Innovative Research (IJMSIR). "A Prospective Study To Assess The Role of Modified Bio Physical Profile and Cerebroplacental Ratio in Prediction of Adverse Perinatal Outcome in Pregnancies Beyond 40 Weeks of Gestation." International Journal of Medical Science and Innovative Research (IJMSIR) 9, no. 6 (2024): 50–56. https://doi.org/10.5281/zenodo.15448879.

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<strong>Abstract</strong> <strong>Aim</strong>: To assess the role of modified bio physical profile and cerebroplacental ratio in prediction of adverse perinatal outcome in pregnancies beyond 40 weeks. <strong>Methodology</strong>: Pregnancies beyond 40 weeks admitted to the labor room were selected based on specific inclusion and exclusion criteria. Informed consent was obtained, and ethical approval was secured from the institute’s review board. A thorough patient assessment was conducted, including a detailed medical history, general and obstetric examinations, and routine investigati

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Olugbenga, O. E., M. O. Momoh, F. I. Omorogbe, et al. "Relationship Between Cerebroplacental Ratio and Fetal Outcome Among Women with Preeclampsia in Irrua, Edo State, Nigeria." British Journal of Healthcare and Medical Research 12, no. 03 (2025): 165–79. https://doi.org/10.14738/bjhr.1203.18854.

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Background: Fetal Doppler ultrasound scan has become a quick way of screening for fetal compromise and determining appropriate management in high-risk pregnancies such as preeclampsia. The role of cerebroplacental ratio for this purpose is being explored. Aim: The aim of this study is to evaluate the relationship between cerebroplacental ratio and fetal outcome among women with preeclampsia. Methodology: This prospective cohort study was among 100 consecutive women with singleton pregnancies and preeclampsia between 34weeks and 37 weeks of gestation, recruited for umbilical and middle cerebral

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Priya, Singh Suryvanshi, Chadar Pratibha, Agrawal Juhi, and Narnoure Ashwani. "Assessment of Cerebroplacental Ratio at 35 to 38 Weeks Gestation and Its Correlation to Perinatal Outcomes: A Two Step Approach." International Journal of Pharmaceutical and Clinical Research 16, no. 6 (2024): 32–37. https://doi.org/10.5281/zenodo.12707166.

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<strong>Background:</strong> Cerebroplacental ratio (CPR) is a reliable indicator of foetus health, measured by colour Doppler. CPR is calculated as ratio of pulsatility index of middle cerebral artery (MCA) and umbilical artery (UA).  When blood is redistributed in the early stages of hypoxia in favor of cerebral circulation, the diastolic flow amplitude increases above normal levels in MCA while umbilical flow in diastole decreases, providing CPR. <strong>Aim:</strong> objective of this study is to investigate the relationship between CPR and adverse perinatal outcomes in

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Nguyen, Tran Thao Nguyen, Van Duc Vo, and Ngoc Thanh Cao. "CORRELATION BETWEEN CEREBROPLACENTAL RATIO AND ADVERSE OUTCOMES IN INTRAUTERINE GROWTH RESTRICTION." Volume 8 Issue 3 8, no. 3 (2018): 82–89. http://dx.doi.org/10.34071/jmp.2018.3.13.

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Objectives: To identify the values of CPR in intrauterine growth restriction and evaluate the correlation between cerebroplacental ratio and adverse outcomes in intrauterine growth restriction. Material and methods: A prospective study was conducted on 74 cases of intrauterine growth restriction with an estimated fetal weight less than 10th percentile, at Departement of Obstetric and Gynecology of Hue University of Medicine and Pharmacy from 05/2016 – 05/2017. CPR was calculated by PIMCA/PIUA.. The adverse outcomes included gestational age at delivery, methods used to delivery, APGAR score bel

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MUSHTAQ, S., M. AMIN, and MMUR KHAN. "PROGNOSTIC ACCURACY OF CEREBROPLACENTAL RATIO FOR ADVERSE FETAL OUTCOMES AND FETAL DISTRESS WITHIN 24 HOURS OF BIRTH." Pakistan Journal of Intensive Care Medicine 5, no. 01 (2025): 86. https://doi.org/10.54112/pjicm.v5i01.86.

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Background: The cerebroplacental ratio (CPR), derived from Doppler indices of the fetal middle cerebral artery and umbilical artery, has emerged as a potential predictor of fetal compromise. Evaluating its prognostic accuracy for adverse perinatal outcomes (APO) and cesarean section for intrapartum fetal distress (CS-IFR) may enhance perinatal risk stratification and decision-making in late gestation. Objective: To evaluate the prognostic accuracy of the cerebroplacental ratio for predicting adverse perinatal outcomes and cesarean section due to fetal distress within 24 hours of delivery. Stud

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Sengodan, Subha S., and Sankari Mathiyalagan. "Doppler study (cerebroplacental ratio) as a predictor of adverse perinatal outcome." International Journal of Reproduction, Contraception, Obstetrics and Gynecology 9, no. 12 (2020): 5068. http://dx.doi.org/10.18203/2320-1770.ijrcog20205249.

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Background: Objective of the current study was to determine the importance of Doppler screening (cerebroplacental ratio i.e. CPR) in antenatal mothers and its effect on perinatal outcome of the baby so that appropriate management can be planned effectively for a better reduction in perinatal mortality and morbidity.Methods: A prospective study conducted on hundred antenatal women in GMKMCH, Salem with gestational age >32 weeks, with singleton pregnancies. Doppler ultrasonogram of fetal middle cerebral artery and umbilical artery and thus CPR obtained.Results: 25 out of the 100 patients in t

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Thomas, Susan, Prameela Menon, and Indu M. Madhu. "Cerebroplacental ratio as a predictor of perinatal outcomes in intrauterine growth restriction." Indian Journal of Obstetrics and Gynecology Research 9, no. 4 (2022): 473–76. http://dx.doi.org/10.18231/j.ijogr.2022.090.

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Intrauterine growth restriction (IUGR) complicates 7-15% of pregnancies and is associated with adverse perinatal outcomes. The primary goal of antenatal care is the early detection of such conditions. Doppler studies in fetus are used to predict the morbidity in IUGR. Studies show that cerebroplacental ratio is a better predictor of IUGR babies and adverse perinatal outcome. In this study we compare perinatal outcomes of IUGR babies with a normal CPR and an abnormal CPR. This prospective cohort study was carried out in the Department of Obstetrics and Gynaecology, Amala Institute of Medical Sc

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Kumari, Swati, Samita Das, and Rachita Pravalina. "Cerebroplacental ratio and its relation to poor perinatal outcomes in singleton pregnancies: a cross sectional study in a tertiary care centre of Eastern India." International Journal of Reproduction, Contraception, Obstetrics and Gynecology 12, no. 7 (2023): 2156–60. http://dx.doi.org/10.18203/2320-1770.ijrcog20231927.

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Background: Detection of fetal growth abnormalities by fetal monitoring is a critical component of perinatal care. Cerebroplacental ratio (CPR), as measured by colour Doppler, has recently been demonstrated to be a reliable indicator of foetus health. CPR is calculated as ratio of pulsatility index of middle cerebral artery (MCA) and umbilical artery (UA). When blood is redistributed in the early stages of hypoxia in favour of cerebral circulation, the diastolic flow amplitude increases above normal levels in MCA while umbilical flow in diastole decreases, providing CPR. This study aims to inv

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Giri, Amrita, Amit Shrestha, and Anshumala Joshi. "Role of Cerebro-Placental Ratio in prediction of adverse perinatal outcome in hypertensive disorder of pregnancy." Nepal Medical College Journal 24, no. 1 (2022): 56–61. http://dx.doi.org/10.3126/nmcj.v24i1.44142.

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Hypertensive disorder of pregnancy is a multisystem disorder associated with an increased risk of perinatal mortality worldwide. Doppler velocimetry of uterine, umbilical, and fetal vessels is an established method of antenatal monitoring identifying fetus at risk. The cerebroplacental ratio (CPR) is emerging as an important predictor of the adverse perinatal outcome as it considers both umbilical and middle cerebral artery doppler. The aim of this study is to find the role of CPR in the prediction of adverse perinatal outcome in the hypertensive disorder of pregnancy. A prospective descriptiv

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Bataeva, R. S., and T. A. Yarygina. "P08.01: Cerebroplacental ratio ( CPR) in fetuses with different estimated weight." Ultrasound in Obstetrics & Gynecology 50 (September 2017): 177. http://dx.doi.org/10.1002/uog.18070.

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Martin-Alonso, Raquel, Valeria Rolle, Ranjit Akolekar, et al. "Efficiency of the Cerebroplacental Ratio in Identifying High-Risk Late-Term Pregnancies." Medicina 59, no. 9 (2023): 1670. http://dx.doi.org/10.3390/medicina59091670.

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Background and Objectives: Over the last few years, great interest has arisen in the role of the cerebroplacental ratio (CPR) to identify low-risk pregnancies at higher risk of adverse pregnancy outcomes. This study aimed to assess the predictive capacity of the CPR for adverse perinatal outcomes in all uncomplicated singleton pregnancies attending an appointment at 40–42 weeks. Materials and Methods: This is a retrospective cohort study including all consecutive singleton pregnancies undergoing a routine prenatal care appointment after 40 weeks in three maternity units in Spain and the United

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International, Journal of Medical Science and Innovative Research (IJMSIR). "Evaluate The Effectiveness of Cerebroplacental Ratio in Predicting Neonatal Outcome in Low Risk Pregnancies with Reduced Fetal Movement in Third Trimester." International Journal of Medical Science and Innovative Research (IJMSIR) 9, no. 6 (2024): 77–84. https://doi.org/10.5281/zenodo.15449526.

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<strong>Abstract</strong> <strong>Introduction: </strong>Antepartum stillbirth significantly contributes to perinatal mortality, surpassing deaths from prematurity and sudden infant death syndrome. <strong>Aim: </strong>To evaluate the effectiveness of CPR in predicting neonatal outcomes in low-risk pregnancies with RFM. <strong>Methodology: </strong>This hospital-based cross-sectional study will be conducted in the Department of Obstetrics and Gynecology at PBM Hospital, Bikaner, over a duration of one year, from September 2023 to August 2024. <strong>Result: </strong>In our study of 300 case

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Safora, Shafaq, Ahmad Lone Sameer, and Qureshi Ambreen. "Association of Cerebro-Placental Ratio with Fetal Outcome in Gestational Hypertensive Kashmiri Pregnant Women." International Journal of Pharmaceutical and Clinical Research 15, no. 6 (2023): 1590–95. https://doi.org/10.5281/zenodo.12511236.

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<strong>Introduction: </strong>The cerebroplacental (CP) ratio is a known indicator of adverse pregnancy outcomes. In the third trimester, CPR should be viewed as a means of evaluation for foetuses. The aim of our study was to determine the association of cerebro-placental ratio with fetal outcome in pregnant Kashmiri women with gestational hypertension. <strong>Materials and Methods: </strong>This prospective research was carried out on 750 patients in the Postgraduate Department of Obstetrics and Gynaecology at the Lalla Ded Hospital, which is affiliated with the GMC Srinagar,

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Batool, Saima, Rabia Bhatti, and Amara Sahar. "Prognostic Power of Cerebroplacental Ratio for Adverse Fetal Outcomes in Women with High-Risk Pregnancies." Biological and Clinical Sciences Research Journal 6, no. 6 (2025): 4–7. https://doi.org/10.54112/bcsrj.v6i6.1790.

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High-risk pregnancies are associated with increased risk of adverse fetal outcomes, including perinatal mortality and morbidity. The cerebroplacental ratio (CPR), derived from Doppler assessment of fetal umbilical artery (UA) and middle cerebral artery (MCA) pulsatility indices (PIs), has been proposed as a non-invasive predictor of such outcomes. However, its predictive accuracy remains variable in clinical practice. Objective: To evaluate the predictive ability of cerebroplacental ratio for adverse fetal outcomes in women with high-risk pregnancies. Methods: This retrospective study was cond

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Ounphamornlah, Natrada, Wiyada Luangdansakul, Nawabhorn Orungrote, et al. "Prevalence of Abnormal Cerebroplacental Ratio in Uncomplicated Full-term Pregnancy and Correlation with Adverse Perinatal Outcomes." Siriraj Medical Journal 76, no. 8 (2024): 514–21. http://dx.doi.org/10.33192/smj.v76i8.267732.

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Objective: To investigate the prevalence of abnormal cerebroplacental ratio (CPR) and predicting values for adverse perinatal outcomes in uncomplicated full-term pregnancies. Materials and Methods: This prospective cross-sectional study was conducted at Bhumibol Adulyadej Hospital, Royal Thai Air Force, Thailand between July and December 2023. The study population comprised pregnant women between the ages 18 and 45 presenting uncomplicated full-term pregnancies. Transabdominal ultrasonography in Doppler color mode was performed on all participants. Umbilical artery pulsatility index (UAPI) and

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Novillo-Del Álamo, Blanca, Alicia Martínez-Varea, Elena Satorres-Pérez, et al. "Cerebroplacental Ratio as a Predictive Factor of Emergency Cesarean Sections for Intrapartum Fetal Compromise: A Systematic Review." Journal of Clinical Medicine 13, no. 6 (2024): 1724. http://dx.doi.org/10.3390/jcm13061724.

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Background: This systematic review aimed to clarify the association between the cerebroplacental ratio (CPR) and emergency cesarean sections (CSs) due to intrapartum fetal compromise (IFC). Methods: Datasets of PubMed, ScienceDirect, CENTRAL, Embase, and Google Scholar were searched for studies published up to January 2024 regarding the relationship between the CPR and the rate of CS for IFC, as well as the predictive value of the CPR. Results: The search identified 582 articles, of which 16 observational studies were finally included, most of them with a prospective design. A total of 14,823

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., Urvashi, Sujani B. K., and Krishna Sai Sushma. "Role of modified biophysical profile and cerebroplacental ratio in fetal outcome in low risk and high risk pregnancies." International Journal of Reproduction, Contraception, Obstetrics and Gynecology 7, no. 3 (2018): 1104. http://dx.doi.org/10.18203/2320-1770.ijrcog20180901.

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Background: The timely detection of morbid changes in the fetal status followed by adequate interventions to avoid death or disability is one of the most important objectives of prenatal care. Objective of present study was to Comparing the role of modified biophysical profile and the cerebroplacental ratio in fetal outcome in low risk and high risk pregnancies.Methods: Two hundred and seventy three singleton pregnant women were included in this study. Following routine examination, amniotic fluid index, pulsatility index of middle cerebral artery and pulsatility index of umbilical artery, ute

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Maity, Abhijan, Bhawana Sonawane, Anagha Deshpande, and Sunita Bhutada. "Diagnostic Accuracy of Cerebroplacental Ratio in Anticipating Adverse Perinatal Outcome in Uncomplicated Appropriate-for-Gestational-Age Pregnancies at Term." Applied Radiology 54, Suppl_1 (2025): 4–11. https://doi.org/10.37549/ar-d-24-0061.

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Abstract Objectives and Hypothesis: Anticipating which babies are in danger of experiencing poor outcomes during the perinatal period in uncomplicated appropriate-for-gestational-age (AGA) pregnancies at term is difficult in obstetric practice. Cerebroplacental ratio (CPR) is emerging as a significant indicator of negative perinatal results. The current study sought to establish the efficacy of CPR in predicting negative perinatal outcomes in term uncomplicated AGA pregnancies. Materials and Methods: This was a hospital-based prospective observational cohort study conducted at a single center.

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GRÜTTNER, BERTHOLD, JESSIKA RATIU, DOMINIK RATIU, et al. "Correlation of Cerebroplacental Ratio (CPR) With Adverse Perinatal Outcome in Singleton Pregnancies." In Vivo 33, no. 5 (2019): 1703–6. http://dx.doi.org/10.21873/invivo.11659.

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Zheng, Jing-jie, Hui-rong Zhao, Min-hong Mao, et al. "Comparison and Analysis of Cerebroplacental Ratio and Umbilicocerebral Ratio in the Prenatal Diagnosis and Severity Assessment of Fetal Growth Restriction: A Retrospective Study and Systematic Review." Archives of Obstetrics and Gynaecology 5, no. 1 (2024): 33–39. http://dx.doi.org/10.33696/gynaecology.5.060.

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Purpose: Doppler flow parameters of fetal umbilical artery (UA) and middle cerebral artery (MCA) have been widely used for fetal growth restriction (FGR), but their diagnostic efficacy remains contentious. The purpose of this study is to clarify the superiority of cerebroplacental ratio (CPR) and umbilicocerebral ratio (UCR) in terms of their correlation and predictive accuracy in diagnosing FGR. Methods: Doppler flow parameters of the UA and MCA were tested for FGR patients and normal pregnant women during the third trimester. Collection of delivery gestational weeks and neonatal birth weight

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Manu, Singhal, Grover Neha, and Chaudhary Suman. "Low Cerebroplacental Ratio as a Predictor of Adverse Perinatal Outcome in Pregnancies Complicated by Fetal Growth Restriction." International Journal of Pharmaceutical and Clinical Research 16, no. 10 (2024): 1016–19. https://doi.org/10.5281/zenodo.14063793.

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<strong>Background:</strong> Though cerebroplacental ratio (CPR) has shown good role in predicting poor perinatal outcomes in normal pregnancies, its role in FGR (fetal growth restriction) pregnancies remains poorly understood. This study aims to evaluate the predictive value of the CPR in determining adverse perinatal outcomes in pregnancies complicated by FGR. <strong>Methods:</strong> A cohort of 100 pregnant women with a gestational age of between 28 and 37 weeks and diagnosed with FGR was assessed and followed up till birth. CPR was calculated using pulsatility index of ute

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Brar, Bobby, Pooja Patil, Rebecca Kolstad, James Alexander, Michael Gardner, and Nora Doyle. "1028: Utility of the cerebroplacental ratio (CPR) in marijuana exposed growth restricted fetuses." American Journal of Obstetrics and Gynecology 222, no. 1 (2020): S639. http://dx.doi.org/10.1016/j.ajog.2019.11.1043.

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Ziade, M., Ibrahim Ghosn, Nabil Helou, and Reem Abu-Rustum. "Normogram of Middle Cerebral Artery Doppler Indexes and Cerebroplacental Ratio at 12 to 14 Weeks in an Unselected Pregnancy Population." American Journal of Perinatology 36, no. 02 (2018): 155–60. http://dx.doi.org/10.1055/s-0038-1661404.

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Objective The aim of this study is to assess the feasibility of visualizing the middle cerebral artery (MCA), establishing the normogram for MCA pulsatility index (PI) and peak systolic velocity (PSV), and calculating cerebroplacental ratio (CPR) at 12 to 14 weeks. Study Design Prospective cross-sectional study on 186 gravidas presenting for nuchal translucency (NT) assessment. Maternal body mass index (BMI), fetal crown-rump length (CRL), biparietal diameter (BPD), and NT were obtained. Color Doppler was utilized to visualize the MCA and measure PI, PSV, and umbilical artery PI. Normograms fo

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Steller, Jon G., Camille Driver, Diane Gumina, John Hobbins, and Henry L. Galan. "665: Calculation of Cerebroplacental Ratio (CPR) using both Umbilical Arteries versus Individual Umbilical Arteries." American Journal of Obstetrics and Gynecology 222, no. 1 (2020): S423. http://dx.doi.org/10.1016/j.ajog.2019.11.680.

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Juhi, Agrawal, Mishra Nitu, Singh Suryavanshi Priya, and Singh Bhati Nandini. "Cerebroplacental Ratio as a Diagnostic Factor of Adverse Perinatal Outcome in 35-38 Weeks in Appropriate for Gestational Age Fetuses." International Journal of Pharmaceutical and Clinical Research 14, no. 9 (2022): 253–60. https://doi.org/10.5281/zenodo.13324156.

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<strong>Objective: </strong>The objectives of this study were to evaluate the diagnostic abilities of the cerebroplacental ratio (CPR) for the prediction of adverse perinatal outcome (APO). <strong>Methods: </strong>This was a study of 200 high-risk fetuses attending the day hospital unit of a tertiary referral hospital that underwent an ultrasound examination at 34–38 weeks . APO was defined as a composite of abnormal intrapartum fetal heart rate or intrapartum fetal scalp pH <7.20 requiring urgent cesarean section, neonatal umbilical cord pH <7.10, 5-min Apgar scor

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Stumpfe, Florian M., Andreas Mayr, Michael O. Schneider, et al. "Cerebroplacental versus Umbilicocerebral Ratio—Analyzing the Predictive Value Regarding Adverse Perinatal Outcomes in Low- and High-Risk Fetuses at Term." Medicina 59, no. 8 (2023): 1385. http://dx.doi.org/10.3390/medicina59081385.

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Background and Objectives: The aim of this study was to investigate the prediction of adverse perinatal outcomes using the cerebroplacental (CPR) and umbilicocerebral (UCR) ratios in different cohorts of singleton pregnancies. Materials and Methods: In this retrospective cohort study, we established our own Multiple of Median (MoM) for CPR and UCR. The predictive value for both ratios was studied in the following outcome parameters: emergency cesarean delivery, operative intervention (OI), OI due to fetal distress, 5-min Apgar < 7, admission to neonatal intensive care unit, and composite ad

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Khanjani, Somayeh, Farinaz Farahbod, Elahe Zarean, Mohammad Javad Tarrahi, and Belgheis Mohammadi. "Evaluation of the relation between cerebroplacental ratio, umbilical-cerebral ratio, and cerebro-placental-uterine ratio with the occurrence of adverse perinatal outcomes in pregnancies complicated by fetal growth restriction." Immunopathologia Persa 9, no. 2 (2023): 39503. http://dx.doi.org/10.34172/ipp.2023.39503.

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Introduction: Fetal growth restriction (FGR) is a major obstetric complication associated with an increased risk of adverse perinatal outcomes. Objectives: This study aimed to evaluate the relationship between Doppler parameters, including the cerebroplacental ratio (CPR), umbilicocerebral ratio (UCR), and cerebro-placental-uterine ratio (CPUR), with adverse perinatal outcomes in singleton pregnancies complicated by FGR. Patients and Methods: This was a prospective study of 100 women with a singleton pregnancy 28 and 36.8 weeks of gestation was complicated by FGR and mild abnormalities. Feto-m

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Reyes-Játiva, Patricio Martin, Esther de los Dolores Jiménez-Andrade, and Washington Omar Guevara-Pérez. "Rol del índice cerebroplacentario y doppler de la arteria uterina en el diagnóstico y pronóstico de la restricción del crecimiento fetal." Revista Metropolitana de Ciencias Aplicadas 8, S1 (2025): 26–31. https://doi.org/10.62452/9dv1p266.

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This study aimed to evaluate the accuracy of the cerebroplacental ratio (CPR) and uterine artery Doppler in predicting adverse perinatal outcomes in cases of fetal growth restriction (FGR). A literature review of studies published since 2014 was conducted, using databases such as PubMed and EMBASE, focusing on cohort and cross-sectional studies that analyzed the relationship between these Doppler parameters and perinatal outcomes. The results showed that CPR had moderate to high accuracy for predicting perinatal death, with pooled sensitivity and specificity of 93% and 76%, respectively. Howev

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Karge, Anne, Silvia M. Lobmaier, Bernhard Haller, Bettina Kuschel, and Javier U. Ortiz. "Value of Cerebroplacental Ratio and Uterine Artery Doppler as Predictors of Adverse Perinatal Outcome in Very Small for Gestational Age at Term Fetuses." Journal of Clinical Medicine 11, no. 13 (2022): 3852. http://dx.doi.org/10.3390/jcm11133852.

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The aim of this study was to evaluate the association between cerebroplacental ratio (CPR), mean uterine artery (mUtA) Doppler and adverse perinatal outcome (APO) and their predictive performance in fetuses with birth weight (BW) <3rd centile (very small for gestational age, VSGA) in comparison with fetuses with BW 3rd–10th centile (small for gestational age, SGA). This was a retrospective cohort study including singleton pregnancies delivered at term (37 + 0–41 + 6) in a single tertiary referral center over a six-year period. APO was defined as a composite of cesarean section for intrapart

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Elhabashy, Ahmed M., Wafaa M. Aboulenein, Tamer M. Abdeldayem, and Moustafa M. Elhabashy. "Predictive performance of fetal aortic isthmus Doppler velocimetry and the cerebro-placental ratio in cases with fetal growth restriction." International Journal of Reproduction, Contraception, Obstetrics and Gynecology 13, no. 12 (2024): 3457–65. http://dx.doi.org/10.18203/2320-1770.ijrcog20243574.

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Background: Fetal growth restriction (FGR) is one of the leading causes of intrauterine fetal demise, cerebral palsy and perinatal death. The main cause of FGR is placental insufficiency. Cerebroplacental ratio (CPR) is decreased with the progression of FGR. Fetal aortic isthmus (AoI) Doppler has been suggested as a useful prognostic marker in monitoring of FGR fetuses. Objective of the study is to evaluate the relation between the AoI Doppler and CPR on the perinatal outcome in cases with FGR. Methods: This is a prospective observational cohort study that entailed 100 cases from November 2022

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Neeru, Malik, Jain Sandhya, Ranjan Rajeev, Agrawal Neha, Maurya Divya, and Malik Vinayak. "A Comparative Study of Antepartum Fetal Surveillance using Cerebroplacental Ratio vs Non-Stress Test in Predicting Perinatal Outcome in Hypertensive Disorders of Pregnancy." International Journal of Pharmaceutical and Clinical Research 16, no. 8 (2024): 65–71. https://doi.org/10.5281/zenodo.13380998.

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<strong>Introduction:</strong> Antepartum fetal surveillance is of immense importance for detecting fetal compromise in utero in high-risk pregnancies. The non-stress test (NST), contraction stress test (CST), biophysical profile (BPP), modified BPP (MBPP), and Doppler velocimetry are among the various tests used to evaluate high-risk pregnancies. This study was conducted to compare the diagnostic efficacy of the cerebroplacental ratio (CPR) and the non-stress test (NST) in predicting fetal compromise in hypertensive disorder of pregnancy (HDP). <strong>Methods: </strong>This is

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Satish Vishwekar, Pallavi, Sudha Rani G, and Abhilasha Jadhav. "DOPPLER ULTRASOUND CEREBROPLACENTAL RATIO (CPR) - A BETTER PREDICTOR OF FOETAL OUTCOME IN CLINICALLY SUSPECTED IUGR PREGNANCIES." Journal of Evolution of Medical and Dental Sciences 5, no. 103 (2016): 7523–26. http://dx.doi.org/10.14260/jemds/2016/1703.

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Sichinava, L. G., D. I. Shishkina, L. E. Breusenko, et al. "Prediction of the risk of adverse perinatal outcomes in pregnant women with fetal growth fetal restriction." Voprosy ginekologii, akušerstva i perinatologii 22, no. 3 (2023): 7–12. http://dx.doi.org/10.20953/1726-1678-2023-2-7-12.

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Objective. Development of additional Doppler criteria for predicting the risk of adverse perinatal outcomes in pregnant women with fetal growth restriction (FGR) Patients and methods. 161 patients with singleton pregnancies were examined: 100 women were diagnosed with АПК, and 31 women had fetuses that were low in weight by gestational age; The control group consisted of 30 patients with normal fetal growth. Ultrasound, in addition to fetometry, included Doppler sonography of blood flow in the uterine arteries, umbilical arteries and the fetal middle cerebral artery. The cerebroplacental ratio

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Draganovic, Dragica, Branka Cancarevic-Djajic, Dragica Jojic, Vesna Ljubojevic, and Jelena Todorovic. "The possibility of clinical use for the oxidative stress marker in correlation with blood flow parameters in pregnancy-induced hypertension." Revista Romana de Medicina de Laborator 29, no. 2 (2021): 143–51. http://dx.doi.org/10.2478/rrlm-2021-0014.

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Abstract Introduction: In pregnancy-induced hypertension (PIH) there is a disorder in placental blood flow which causes intrauterine fetal hypoxia, and oxidative stress has a significant role in this condition. The aims of this research were to analyze the relation of thiobarbituric acid reactive substance (TBARS), as a marker of oxidative stress and absent end-diastolic flow (AEDF), as well as the relation of TBARS and cerebroplacental ratio (CPR). Methods: The research included 200 pregnant women in the gestation period from 28th to 40th, 100 were in a control group and 100 were with PIH. Th

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Rossi, A., L. Forzano, G. Baccarini, I. Romanello, G. Fachechi, and D. Marchesoni. "OP33.07: Three dimensional cerebroplacental ratio (CPR 3DPDA): a new parameter for the antenatal surveillance in IUGR fetuses." Ultrasound in Obstetrics & Gynecology 40, S1 (2012): 155. http://dx.doi.org/10.1002/uog.11713.

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Karabay, Gulsan, Burak Bayraktar, Zeynep Seyhanli, et al. "Evaluation of Conventional and Combined Doppler Parameters in Preeclampsia: Diagnostic and Prognostic Insights." Journal of Clinical Medicine 14, no. 2 (2025): 647. https://doi.org/10.3390/jcm14020647.

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Background: The aim of this study was to examine the relationship between conventional and novel Doppler parameters, including cerebroplacental ratio (CPR), cerebral–placental–uterine ratio (CPUR), umbilical-to-cerebral ratio (UCR), and amniotic-to-umbilical-cerebral ratio (AUCR), with the diagnosis of preeclampsia (PE) and adverse neonatal outcomes in PE cases. Methods: This prospective case-control study was conducted at the Ankara Etlik City Hospital Perinatology Clinic between November 2023 and May 2024. The study population was divided into two groups: Group 1, consisting of 74 patients d

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Pinsuti, Ederlei Munhoz, Rafael Frederico Bruns, Jaime Kulak Júnior, et al. "Analysis of the Correlation/Agreement of Maternal–fetal Doppler Parameters in Normal and Growth-Restricted Fetuses." Revista Brasileira de Ginecologia e Obstetrícia / RBGO Gynecology and Obstetrics 44, no. 02 (2022): 118–24. http://dx.doi.org/10.1055/s-0041-1741453.

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Abstract Objective To assess the degree of correlation/agreement of maternal–fetal Doppler parameters between normal and growth-restricted fetuses (fetal growth restriction [FGR]). Methods The present observational and retrospective study included 274 singleton pregnancies. The following maternal–fetal Doppler parameters were assessed: uterine artery (UAt), umbilical artery (UA), middle cerebral artery (MCA), cerebroplacental ratio (CPR), and umbilical–cerebral ratio (U/C). The assessment of FGR was based on the Figueiras and Gratacós9 criteria. Spearman correlation coefficients were estimated

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Sherrell, Helen, Vicky Clifton, and Sailesh Kumar. "Predicting intrapartum fetal compromise at term using the cerebroplacental ratio and placental growth factor levels (PROMISE) study: randomised controlled trial protocol." BMJ Open 8, no. 8 (2018): e022567. http://dx.doi.org/10.1136/bmjopen-2018-022567.

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IntroductionIntrapartum complications are a major contributor to adverse perinatal outcomes, including stillbirth, hypoxic–ischaemic brain injury and subsequent longer term disability. In many cases, hypoxia develops as a gradual process due to the inability of the fetus to tolerate the stress of parturition suggesting reduced fetoplacental reserve before labour commences. The fetal cerebroplacental ratio (CPR) is an independent predictor of intrapartum fetal compromise, poor acid base status at birth and of neonatal unit admission at term. Similarly, circulating maternal levels of placental g

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Etchegaray, A., J. Moren, R. Ciammella, and M. Esteban. "OP03.01: Cerebroplacental ratio (CPR) at term as a marker of intrapartum placental reserve: results of a retrospective cohort." Ultrasound in Obstetrics & Gynecology 48, S1 (2016): 57. http://dx.doi.org/10.1002/uog.16176.

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Sulaiman, Bilal, Aliyu Y. Isah, Habiba I. Abdullahi, et al. "Umbilical and middle cerebral arteries Doppler velocimetry in early and late onset pre-eclampsia." International Journal of Reproduction, Contraception, Obstetrics and Gynecology 11, no. 2 (2022): 338. http://dx.doi.org/10.18203/2320-1770.ijrcog20220157.

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Background: Pre-eclampsia (PE) is a multisytemic disorder originating from the placenta with a high prevalence in sub-Saharan Africa. Early (<34 weeks) and late (>34 weeks) – onset PE have different maternal and perinatal outcomes with overlapping clinical features. Differences in Doppler velocimetry pattern in these subgroups appears unsettled.Methods: In a prospective cohort study, 110 pregnant women with singleton pregnancy diagnosed with PE were recruited and had umbilical and middle cerebral arteries (MCA) Doppler velocimetry done. The pregnancies were followed up to delivery and ou

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Raj, Krithika, and Sheela S. R. "The efficacy of doppler indices in predicting the neontal outcome in term preeclamptic women with intrauterine growth restriction: an observational study in a tertiary care centre." International Journal of Reproduction, Contraception, Obstetrics and Gynecology 9, no. 5 (2020): 2087. http://dx.doi.org/10.18203/2320-1770.ijrcog20201810.

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Background: Doppler flow velocimetry of the umbilical and fetal cerebral circulation is a non-invasive modality used to access the fetal well-being. Doppler is comparatively more specific and is potentially a useful tool in predicting adverse perinatal outcome in high risk cases. Objectives of this study were to evaluate the efficacy of Middle cerebral artery pulsatility index (MCA-PI), umbilical artery pulsatility index (UA-PI) and cerebroplacental ratio (CPR) doppler indices in assessment of fetal well-being. To document neonatal outcome in preeclamptic women with doppler changes.Methods: A

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Şirinoğlu, Hicran, Kadir Atakır, Savaş Özdemir, Merve Konal, and Veli Mihmanlı. "Middle cerebral artery to uterine artery pulsatility index ratios in pregnancy with fetal growth restriction regarding negative perinatal outcomes." Journal of Surgery and Medicine 6, no. 9 (2022): 788–91. http://dx.doi.org/10.28982/josam.7319.

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Background/Aim: Fetal growth restriction (FGR) causes a high risk of perinatal morbidity and mortality, and the timing of the correct delivery time decision remains controversial. Cerebroplacental ratio (CPR), umbilical artery, uterine artery (UA) and middle cerebral artery (MCA) Doppler studies are used to predict adverse perinatal outcomes in FGR. However, since there is insufficient reliability for each separately and together, the search for new methods continues. This retrospective study was conducted to determine the degree of neonatal morbidity in fetuses suspected of having FGR by eval

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Stampalija, T., B. Arabin, H. Wolf, C. M. Bilardo, and C. Lees. "An abnormal cerebroplacental ratio (CPR) is predictive of early childhood delayed neurodevelopment in the setting of fetal growth restriction." American Journal of Obstetrics and Gynecology 222, no. 4 (2020): 391–92. http://dx.doi.org/10.1016/j.ajog.2019.12.012.

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Monteith, Cathy, Karen Flood, Ragamallika Pinnamaneni, et al. "An abnormal cerebroplacental ratio (CPR) is predictive of early childhood delayed neurodevelopment in the setting of fetal growth restriction." American Journal of Obstetrics and Gynecology 221, no. 3 (2019): 273.e1–273.e9. http://dx.doi.org/10.1016/j.ajog.2019.06.026.

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Kuo, Katherine, and Christy Pylypjuk. "The utility of the cerebroplacental ratio (CPR) in predicting cesarean delivery and neonatal morbidity amongst pregnant patients with diabetes." Journal of Obstetrics and Gynaecology Canada 45, no. 5 (2023): 360. http://dx.doi.org/10.1016/j.jogc.2023.03.061.

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Bowkalow, Sandy, Ekkehard Schleussner, Christiane Kähler, Uwe Schneider, Thomas Lehmann, and Tanja Groten. "Pentaerythrityltetranitrate (PETN) improves utero- and feto-placental Doppler parameters in pregnancies with impaired utero-placental perfusion in mid-gestation – a secondary analysis of the PETN-pilot trial." Journal of Perinatal Medicine 46, no. 9 (2018): 1004–9. http://dx.doi.org/10.1515/jpm-2017-0238.

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AbstractAim:In pregnancies complicated by impaired utero-placental perfusion, pentaeritrithyltetranitrate (PETN) has been shown to reduce the risk of severe fetal growth restriction (FGR) and perinatal death by 39%. The effect is most likely related to the vasodilatative influence of PETN. To assess its impact on utero-placental and fetal perfusion, we analyzed the Doppler parameters measured during the PETN pilot-trial.Methods:One hundred and eleven pregnancies presenting impaired utero-placental resistance at mid-gestation were included in the trial. Fifty-four women received PETN, while 57

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Bano, Nosheen, and Inayat Shah Roghani. "COMPARISON OF DIAGNOSTIC VALUES OF DOPPLER INDICES FOR PREDICTING THE INTRAUTERINE GROWTH RETARDATION (IUGR) IN PREECLAMPTIC WOMEN." Insights-Journal of Health and Rehabilitation 3, no. 2 (Health & Allied) (2025): 340–47. https://doi.org/10.71000/q151rw72.

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Background: Intrauterine growth restriction (IUGR) is a significant complication of preeclampsia, contributing to increased perinatal morbidity and mortality. Timely detection of IUGR through non-invasive modalities such as Doppler ultrasonography can enable early interventions and improve neonatal outcomes. Among various Doppler indices, the cerebroplacental ratio (CPR), umbilical artery pulsatility index (UA-PI), and middle cerebral artery pulsatility index (MCA-PI) have been commonly employed, though their diagnostic accuracy in preeclamptic populations remains under investigation. Objectiv

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Turgut, Ezgi, Sule Goncu Ayhan, Eda Ozden Tokalioglu, et al. "Evaluation of Foetal Doppler After Maternal Covid-19 Disease: How Does Foetal Aortic Isthmus Doppler Change?" Medical Science and Discovery 9, no. 1 (2022): 39–43. http://dx.doi.org/10.36472/msd.v9i1.653.

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Objective: We aim to evaluate the foetal aortic isthmus Doppler data after maternal COVID-19 disease. Material and Methods: Twenty six pregnant patient who recovered from COVID-19 and 43mhealthy patient were included in this prospective case–control study. The study group consisted of those who had COVID-19 disease and completed the quarantine period. Results: Doppler ultrasound evaluations were performed at the similar gestational week. We observed significantly high pulsatility indices (PI) of umbilical and aortic isthmus in study group than the control group (p=0,02, p=0,02). There was no s

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