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1

Józsa, László, and Erzsébet Fóthi. "Cranial surgery and cranioplastica in Hungarian conquest period." Orvosi Hetilap 149, no. 10 (March 1, 2008): 469–72. http://dx.doi.org/10.1556/oh.2008.h-2168.

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2

Manó, Sándor, Kornélia Kovács, Ágnes Éva Kovács, Loránd Csámer, and Zoltán Csernátony. "3D nyomtatás és csontcement alapú cranioplastica mérése mechanikai szempontból." Biomechanica Hungarica 13, no. 1 (December 2020): 29–39. http://dx.doi.org/10.17489/biohun/2020/1/03.

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A cranioplastica egy olyan sebészi eljárás, amely során helyreállítják a koponyán keletkezett defektust. A modern orvostudományt a beteg specifikus eljárások térhódítása jellemzi, ennek egyik formája a 3D nyomtatók alkalmazása. Az általunk alkalmazott módszer során ezt a technológiát használjuk a geometriailag megfelelő pótlások elkészítéséhez. Kutatásunk alapgondolata, hogy az implantátumok beültetés után azonos mechanikai hatásoknak vannak kitéve, mint az ép koponya, így ezeknek az implantátumoknak nemcsak esztétikai és biokompatibilitási, hanem teherbírási szempontból is meg kell felelniük. Vizsgálatunk ennek mérését tűzte ki célul. 10 macerált calvarian dolgoztunk. Elméletünk alapja, hogy a koponyák szimmetrikusak. Ebből kifolyólag, ha az egyik oldalon készítünk egy defektust, és a másik oldal tükrözésével előállítunk egy pótlást, akkor a két oldalt külön-külön mechanikai hatásnak kitéve mérni tudjuk az ép és a pótolt koponya felek teherbíró képességét, ezek alapján pedig összehasonlíthatjuk az azonos koponyák ép és pótolt felének adatait. A vizsgálat során a nyomtatáshoz MED 610 fényre keményedő műgyantát, az öntőforma elkészítéséhez RTV 245 kétkomponensű szilikont használtunk, a végleges pótláshoz pedig polimetil-metakrilát (PMMA) alapú Cemfix 3 csontcementet. Első lépésként létrehoztuk a defektusokat, majd CT felvételt készítettünk, amik alapján erre a célra tervezett számítógépes szoftverrel (Mimics Innovation Suite) megalkottuk a koponyák 3D modelljét, majd megszerkesztettük a pótlást. A pótlások nyomtatása után a szilikon öntőformákat gyártottuk le, amelyekbe később csontcementet öntve elkészültek a végleges implantátumok. A mechanikai teherbírás vizsgálatokat egy Instron 8874 típusú biomechanikai anyagvizsgáló berendezéssel végeztük el. A tönkremenetelhez szükséges erők a koponyák különbözősége miatt elég nagy változatosságot mutattak mind a pótlással rendelkező, mind a pótlás nélküli modelleken. Pótlással átlagban 1585,6 N-t 57,5%- os szórással; pótlás nélkül 2785,7 N-t kaptunk 69,35%-os szórás mellett. Ezek alapján a pótolt és ép koponyák teherbírásának aránya 2,97-nek adódott. A vastagságot is figyelembe véve ez az érték 2,64-re módosult, a szórás csökkenése mellett. A törés gyakorlatilag minden esetben a pótláson következett be. A pótlással történt mérés során az átlagos teherbírás több mint 150 kg-nak, a legkisebb érték 38,58 kgnyi behatásnak felel meg, amely a mindennapi tevékenység során a koponyát érő terheléseknél kevesebb. Az eredmények alapján jelentős erőbehatás esetén a pótlások törése megakadályozza a koponya törését, amely jóval veszélyesebb sérüléssel járna.
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3

Drapkin, Allan J. "Hidrocéfalo, es una complicación o una consecuencia de la craniectomía descompresiva?" Revista Chilena de Neurocirugía 45, no. 3 (December 19, 2019): 216–18. http://dx.doi.org/10.36593/rev.chil.neurocir.v45i3.137.

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La craniectomía descompresiva, un procedimiento de rescate que está siendo utilizado con frecuencia creciente, está afectadapor un número de complicaciones, una de las cuales es la hidrocefalia. Aquí Se efectuó una cuidadosa revisión de la literatura relacionada directa o indirectamente con estos tópicos con el objeto de detectar posibles conexiones entre el procedimiento descompresor y la génesis de hidrocefalia. Quedó en evidencia que existe una relación directa entre ambas condiciones. Por ello, reduciendo el tiempo en el cual el proceso descompresivo interfiere con la fisiología intracraneana al efectuar una cranioplastica lo más temprana posible, debiera evitar o disminuir la posibilidad del desarrollo de hidrocefalia.
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4

Linney, A. D., A. C. Tan, R. Richards, J. Gardener, and W. R. Lees. "Visualizzazione tridimensionale del corpo umano per diagnosi e per programmazione chirurgica." Rivista di Neuroradiologia 5, no. 4 (November 1992): 483–88. http://dx.doi.org/10.1177/197140099200500412.

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Viene descritto un sistema che produce rappresentazioni di superfici anatomiche basandosi su immagini ottenute mediante tomografia assiale computerizzata a raggi X, risonanza magnetica ed ecografia. Le rappresentazioni vengono create per mostrare il carattere tridimensionale (3D) dell'anatomia interna ed esterna. Le immagini possono essere sezionate e manipolate sullo schermo come se fossere l'oggetto tridimensionale che rappresentano. Con questo sistema è possibile pianificare interventi chirurgici per simulazione. È inoltre possibile esporre ed isolare strutture sottostanti di un oggetto anatomico, aumentando così il valore diagnostico dei dati di partenza. Tale sistema di rappresentazione fornisce anche dati per l'azionamento di una fresatrice a controllo numerico per la produzione di modelli anatomici, protesi e impianti. Le esigenze di pianificazione nella chirurgia maxillofacciale sono particolarmente marcate. Va considerata sia la funzione, sia l'estetica facciale1. I sistemi di pianificazione ricorrono ad una combinazione di fotografie, modelli e radiografie planari nel tentativo di tenere conto della natura tridimensionale dell'anatomia. Quindici anni fa i progressi nella tecnologia informatica e della rappresentazione, insieme alla disponibilità della tomografia assiale computerizzata a raggi X (TC), permisero di avviare la creazione di una unità di lavoro per clinici facente uso di grafici al computer per simulare, pianificare e prevedere il risultato della chirurgia maxillofacciale. Benchè inizialmente le applicazioni cliniche fossero alquanto limitate, esse sono notevolmente aumentate con il costante miglioramento dei computer e degli algoritmi. Oltre alle applicazioni originarie, esse comprendono ora: la cranioplastica, la diagnosi radiologica complessa, l'analisi di fratture, l'osservazione del feto e la produzione di impianti scheletrici adattati. Sono allo stato esplorativo le applicazioni in campo neurologico.
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Alvim, Jair Pimentel, Leandro Ururahy de Carvalho, Claudio Russio de Oliveira, Carlos Kossak, Paolo Souto Maior, Gustavo Teles, and Igor Saint Clair. "Protótipo para realização de cranioplastia de baixo custo." Arquivos Brasileiros de Neurocirurgia: Brazilian Neurosurgery 33, no. 04 (December 2014): 318–22. http://dx.doi.org/10.1055/s-0038-1626233.

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Resumo Objetivo: O presente trabalho propõe uma técnica para realização de cranioplastia com metilmetacrilato em formas pré-moldadas e esterilizadas visando evitar cranioplastia com prototipagem pré-moldada. Método: Conforme rotina apresentada, o flap ósseo realizado para craniotomia descompressiva é armazenado em recipientes com formol e enviado para o serviço de patologia do hospital. Quando realizamos a cranioplastia, utilizamos o flap ósseo armazenado para realização dos moldes que serão utilizados na cranioplastia. Resultado: O resultado estético é muito bom e os índices de complicação e infecção são baixos. Conclusão: Apresenta resultados estéticos semelhantes aos casos de prototipagem com baixo custo na confecção.
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6

Souza, Lucas Santos, Ainatna Adgena de Carvalho Santos, João Victor de Andrade Carvalho, Amanda Gomes Lima Bezerra, Alexia Morgana Santos Sales, Marco Antonio Silva Robles, Luciana Montalvão Gois Figueiredo de Almeida, Maria Clara da Silva Castro, Nathan Correia Freire, and Bruno Fernandes de Oliveira Santos. "Risco infeccioso do uso de biomateriais para cranioplastia: polimetilmetacrilato vs. osso autólogo." Research, Society and Development 11, no. 8 (June 6, 2022): e0511830483. http://dx.doi.org/10.33448/rsd-v11i8.30483.

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Este estudo objetivou descrever os riscos infecciosos do uso de osso autólogo e PMMA na cranioplastia. Trata-se de uma revisão integrativa da literatura de natureza qualitativa e caráter descritivo. O levantamento bibliográfico foi executado no mês de março e abril de 2022 mediante busca nas bases e bibliotecas de dados da Scientific Electronic Library Online (SciELO), Biblioteca Virtual em Saúde (BVS), Public Medline (PubMed) e Science Direct. Os critérios de inclusão para seleção dos estudos foram: artigos publicados na íntegra entre os anos de 2013 a 2022, no idioma inglês. Como critérios de exclusão foram: monografias, dissertações, teses, Trabalhos de Conclusão de Curso (TCC), publicações em anais de eventos, revisões de literatura e artigos duplicados em uma ou mais bases de dados. Mediante análise dos artigos inclusos nesta revisão, alguns autores ponderam que não há diferenças significativas em relação ao risco infeccioso no uso da prótese de PMMA e do osso autólogo, como matéria-prima da cranioplastia. Um estudo avaliou o impacto do uso de antibióticos em próteses de PMMA na cranioplastia com defeitos moderados a grandes. Já outro estudo, analisou o uso de PMMA pré-fabricado e pré-esterilizado como material de cranioplastia na população indiana. Um estudo diz que a craniotomia prévia e a cranioplastia com PMMA foram associadas à maior taxa de infecção pós-operatória. Em outro artigo, a reconstrução craniana com osso autólogo apresentou maiores complicações. O uso de PMMA na cranioplastia comparado ao osso autólogo apresenta desfechos diferentes na literatura.
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Custódio, Antonlo Luis Neto, Gilson Côrreia Beltrão, and Carlos Marcelo Severo. "Enxertos ósseos autógeno em cranioplastia." Revista da Faculdade de Odontologia de Porto Alegre 35, no. 2 (July 21, 2021): 9–11. http://dx.doi.org/10.22456/2177-0018.111094.

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A review of the osteoplastic reconstruction of cranioplasty has been presented. The repair of skull defects usin free osteoperiosteal grafts from the outer table of the same part of skull on the others side is described.
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Hara, Tatiana, Clarice Abreu dos Santos Albuquerqu Farias, Mayra Joan Marins da Costa, and Ricardo Jose Lopes da Cruz. "Cranioplastia: parietal versus prótese customizada." Revista Brasileira de Cirurgia Plástica (Impresso) 26, no. 1 (March 2011): 32–36. http://dx.doi.org/10.1590/s1983-51752011000100008.

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9

MARICEVICH, PABLO, ANDRÉ MANSUR, ACRYSIO PEIXOTO, JULIA AMANDO, EDUARDO PANTOJA, ANDRÉ BRAUNE, JOSÉ AUGUSTO NASSER, and RICARDO LOPES DA CRUZ. "Cranioplasties: surgical reconstruction strategies." Revista Brasileira de Cirurgia Plástica (RBCP) – Brazilian Journal of Plastic Sugery 31, no. 1 (2016): 32–42. http://dx.doi.org/10.5935/2177-1235.2016rbcp0006.

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10

Poetker, David M., Kristen B. Pytynia, Glenn A. Meyer, and P. Ashley Wackym. "Complication Rate of Transtemporal Hydroxyapatite Cement Cranioplasties: A Case Series Review of 76 Cranioplasties." Otology & Neurotology 25, no. 4 (July 2004): 604–9. http://dx.doi.org/10.1097/00129492-200407000-00031.

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11

van Gool, Alexander V. "Preformedpolymethylmethacrylate cranioplasties: Report of 45 cases." Journal of Maxillofacial Surgery 13 (1985): 2–8. http://dx.doi.org/10.1016/s0301-0503(85)80005-9.

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Lo, Andrea Y., Roy P. Yu, Anjali C. Raghuram, Michael N. Cooper, Holly J. Thompson, Charles Y. Liu, and Alex K. Wong. "Tissue Expanders in Staged Calvarial Reconstruction: A Systematic Review." Archives of Plastic Surgery 49, no. 06 (November 2022): 729–39. http://dx.doi.org/10.1055/s-0042-1751104.

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AbstractCranioplasties are common procedures in plastic surgery. The use of tissue expansion (TE) in staged cranioplasties is less common. We present two cases of cranioplasties with TE and systematically review literature describing the use of TE in staged cranioplasties and postoperative outcomes. A systematic review was performed by querying multiple databases. Eligible articles include published case series, retrospective reviews, and systematic reviews that described use of TE for staged bony cranioplasty. Data regarding study size, patient demographics, preoperative characteristics, staged procedure characteristics, and postoperative outcomes were collected. Of 755 identified publications, 26 met inclusion criteria. 85 patients underwent a staged cranioplasty with TE. Average defect size was 122 cm2, and 30.9% of patients received a previous reconstruction. Average expansion period was 14.2 weeks. The most common soft tissue closures were performed with skin expansion only (75.3%), free/pedicled flap (20.1%), and skin graft (4.7%). The mean postoperative follow-up time was 23.9 months. Overall infection and local complication rates were 3.53 and 9.41%, respectively. The most common complications were cerebrospinal fluid leak (7.1%), hematoma (7.1%), implant exposure (3.5%), and infection (3.5%). Factors associated with higher complication rates include the following: use of alloplastic calvarial implants and defects of congenital etiology (p = 0.023 and 0.035, respectively). This is the first comprehensive review to describe current practices and outcomes in staged cranioplasty with TE. Adequate soft tissue coverage contributes to successful cranioplasties and TE can play a safe and effective role in selected cases.
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van Gool, A. V. "Preformed polymethylmethacrylate Cranioplasties: Report of 45 cases." Plastic and Reconstructive Surgery 77, no. 4 (April 1986): 687. http://dx.doi.org/10.1097/00006534-198604000-00051.

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Joffe, J. M., B. Aghaheigi, E. H. Davies, and M. Harris. "A retrospective study of 66 titanium cranioplasties." British Journal of Oral and Maxillofacial Surgery 31, no. 3 (June 1993): 144–48. http://dx.doi.org/10.1016/0266-4356(93)90112-a.

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van de Vijfeijken, Sophie E. C. M., Tijmen J. A. G. Münker, Rene Spijker, Luc H. E. Karssemakers, William P. Vandertop, Alfred G. Becking, Dirk T. Ubbink, et al. "Autologous Bone Is Inferior to Alloplastic Cranioplasties: Safety of Autograft and Allograft Materials for Cranioplasties, a Systematic Review." World Neurosurgery 117 (September 2018): 443–52. http://dx.doi.org/10.1016/j.wneu.2018.05.193.

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Samra Majeed, Ajmal Khan, Muhammad Irfan, Shahzaib Tasdique, Azam Niaz, Waqar Azim, and Anjum Habib Vohra. "Outcomes of Cranioplasty after Craniectomy." Pakistan Journal Of Neurological Surgery 26, no. 1 (April 1, 2022): 120–25. http://dx.doi.org/10.36552/pjns.v26i1.649.

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Objective: Craniectomy is a widely used procedure in neurosurgery that results in more cranioplasties to repair skull defects. The complication rate after cranioplasties seems to be higher than elective craniotomies so this study was conducted to determine the outcome of cranioplasty after craniectomy. Materials & Methods: The patients included in this study had craniectomy and cranioplasty for any indication. Patients included had variables, such as age, sex, underlying pathology, craniectomy and cranioplasty dates, the material used for cranioplasty (autologous bone or methyl methacrylate), and methods of cranioplasty flap fixation (sutures or titanium plates and screws) follow up period and complications. Results: It was concluded that patients in the age group of 41 – 60 years (5 cases), males (7 cases), cranioplasty performed after 6 months (5cases) with autologous bone graft (8cases) were associated with more complications. Conclusion: The overall rate of complications associated with cranioplasties is not negligible, however, early cranioplasty in young patients with the use of polymethyl methacrylate may be associated with less complication rate. Keywords: Decompressive, Craniectomy, Cranioplasty, Autologous, Polymethyl Methacrylate
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Garcia, Luiz, Luanna Martins, and Rodrigo Faleiro. "Cranioplastia externa para a síndrome do trefinado – nota técnica." Arquivos Brasileiros de Neurocirurgia: Brazilian Neurosurgery 34, no. 04 (October 2, 2015): 338–41. http://dx.doi.org/10.1055/s-0035-1564823.

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Bouetel, V., P. Roulé, A. Danton, and R. C. Rémy. "Cranioplastie par lambeau libre ostéomusculaire temporo-pariétal." Revue de Stomatologie et de Chirurgie Maxillo-faciale 106, no. 1 (February 2005): 22–26. http://dx.doi.org/10.1016/s0035-1768(05)85796-1.

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Evins, Alexander I., John Dutton, Sayem S. Imam, Amal O. Dadi, Tao Xu, Du Cheng, Philip E. Stieg, and Antonio Bernardo. "On-Demand Intraoperative 3-Dimensional Printing of Custom Cranioplastic Prostheses." Operative Neurosurgery 15, no. 3 (January 13, 2018): 341–49. http://dx.doi.org/10.1093/ons/opx280.

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Abstract BACKGROUND Currently, implantation of patient-specific cranial prostheses requires reoperation after a period for design and formulation by a third-party manufacturer. Recently, 3-dimensional (3D) printing via fused deposition modeling has demonstrated increased ease of use, rapid production time, and significantly reduced costs, enabling expanded potential for surgical application. Three-dimensional printing may allow neurosurgeons to remove bone, perform a rapid intraoperative scan of the opening, and 3D print custom cranioplastic prostheses during the remainder of the procedure. OBJECTIVE To evaluate the feasibility of using a commercially available 3D printer to develop and produce on-demand intraoperative patient-specific cranioplastic prostheses in real time and assess the associated costs, fabrication time, and technical difficulty. METHODS Five different craniectomies were each fashioned on 3 cadaveric specimens (6 sides) to sample regions with varying topography, size, thickness, curvature, and complexity. Computed tomography-based cranioplastic implants were designed, formulated, and implanted. Accuracy of development and fabrication, as well as implantation ability and fit, integration with exiting fixation devices, and incorporation of integrated seamless fixation plates were qualitatively evaluated. RESULTS All cranioprostheses were successfully designed and printed. Average time for design, from importation of scan data to initiation of printing, was 14.6 min and average print time for all cranioprostheses was 108.6 min. CONCLUSION On-demand 3D printing of cranial prostheses is a simple, feasible, inexpensive, and rapid solution that may help improve cosmetic outcomes; significantly reduce production time and cost—expanding availability; eliminate the need for reoperation in select cases, reducing morbidity; and has the potential to decrease perioperative complications including infection and resorption.
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Mommaerts, Maurice Y., Paul R. Depauw, and Erik Nout. "Ceramic 3D-Printed Titanium Cranioplasty." Craniomaxillofacial Trauma & Reconstruction 13, no. 4 (July 16, 2020): 329–33. http://dx.doi.org/10.1177/1943387520927916.

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Study Design: Inlay cranioplasties following partial craniectomy in tumor or trauma cases and onlay cranioplasties for reconstructions of residual developmental skull anomalies are frequently performed using CAD-CAM techniques. Objective: In this case series, we present a novel cranial implant design, being a combination of 3D-printed titanium grade 23 and calcium phosphate paste (CeTi). Methods: The titanium patient-specific implant, manufactured using selective laser melting, has a latticed border with interconnected micropores. The cranioplasty is miniscrew fixed and its border zone subsequently partially filled with calcium phosphate paste to promote osteoinduction and osteoconduction. From April 2017 to April 2019, 8 patients have been treated with such a CeTi implant. The inlay cranioplasties were each time revision surgeries of complicated cases. Results: All implants were successful after a limited follow-up time (range 18-42 months). There were no dehiscences and no infections, and no complaints of thermal conduction. Conclusions: The proposed CeTi cranial implant combines the strength of titanium implants with the biological integration potential of ceramic implants and seems particularly resistant to infection, probably due to the biofunctionalized titanium surface and the antimicrobial activity of elevated intracellular free calcium levels.
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Benzel, E. C., K. Thammavaram, and L. Kesterson. "The diagnosis of infections associated with acrylic cranioplasties." Neuroradiology 32, no. 2 (1990): 151–53. http://dx.doi.org/10.1007/bf00588566.

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Cardoso, Laís Inês Silva, Sérgio Éberson da Silva Maia, João Marques Mendes Neto, Renato da Costa Ribeiro, Carlos Eduardo Mendonça Batista, and Simei André da Silva Rodrigues Freire. "Cranioplastia de frontal com malha de titânio após Craniectomia Descompressiva." Jornal de Ciências da Saúde do Hospital Universitário da Universidade Federal do Piauí 4, no. 2 (November 19, 2021): 27–35. http://dx.doi.org/10.26694/jcshuufpi.v4i2.1003.

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O osso frontal compõe a região anterior do crânio e suas principais funções são proteger o encéfalo de traumas diretos e infecções. Na ocorrência de perda de parte desse osso, há uma desarmonia funcional e anatômica, sendo indicada sua reconstrução. O objetivo deste trabalho é apresentar um relato de cranioplastia de osso frontal, decorrente de uma craniectomia descompressiva de urgência, utilizando como material a malha de titânio. Relato do caso: Paciente do gênero masculino, 32 anos, apresentou-se ao serviço de cirurgia bucomaxilofacial do Hospital Universitário da Universidade Federal do Piauí com queixa de “sofri um acidente e afundou meu rosto”. Vítima de acidente motociclístico há cerca de 12 meses antes da consulta citada, foi submetido à uma cirurgia do tipo craniectomia descompressiva, onde foi removido parte do seguimento ósseo frontal cominuído durante o trauma, permanecendo com defeito ósseo resultante da abordagem neurocirúrgica, abrangendo as corticais externa e interna do osso frontal. A partir da queixa principal, resultados dos exames clínico e de imagem foi proposto a cranioplastia para recontrução do osso frontal com malha de titânio. Para o embasamento teórico do caso foi realizado levantamento bibliográfico acerca do tema na base PubMed, utilizando os descritores: Fratura do crânio com afundamento; Osso frontal; Titânio, foram selecionados artigos que apresentaram discussão referente à escolha do material de reconstrução. Resultados: a instalação e adaptação da malha de titanio possibilitou a correção do defeito na região frontal, favorecendo a proteção do encefalo e restabelecendo a estética do terco superior da face. Conclusão: Diversos materiais de reconstrução são citados na literatura, entretanto, nenhum contempla todas as caracteristicas ideaias para todos os casos.O titânio é considerado uma excelente opção em termos de força, baixos índices de infecção, alta biocompatibilidade e por ser biologicamente inerte. A cranioplastia para reconstrução do osso frontal possibilita o restabelecimento estético e funcional nos casos de defeitos extensos onde a perda do arcabouço de proteção do encefalo além de alteração do contorno do terco superior da face gera tambem uma suceptibilidade a injúrias das estruturas intracranianas.
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ogeswaran, S. Y. "Customized Modeling and Manufacturing of Cranioplastic Implant using Rapid Prototyping." International Journal of Current Engineering and Technology 2, no. 2 (January 1, 2010): 155–61. http://dx.doi.org/10.14741/ijcet/spl.2.2014.28.

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Schmidt, RichardH, ChristinaM Sayama, and Mohammad Sorour. "Dural adhesion to porous cranioplastic implant: A potential safety concern." Surgical Neurology International 5, no. 1 (2014): 19. http://dx.doi.org/10.4103/2152-7806.127377.

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Roberson, John B., Jimmie L. Harper, Robert Horton, and William S. Rosenberg. "Traumatic cranial defects reconstructed with the HTR-PMI cranioplastic implant." British Journal of Oral and Maxillofacial Surgery 35, no. 6 (December 1997): 449. http://dx.doi.org/10.1016/s0266-4356(97)90760-9.

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Smirnov, Igor V., Roman V. Deev, Ilya I. Bozo, Alexander Yu Fedotov, Alex N. Gurin, Vasily E. Mamonov, Alexander D. Kravchuk, Vladimir K. Popov, Alex A. Egorov, and Vladimir S. Komlev. "Octacalcium phosphate coating for 3D printed cranioplastic porous titanium implants." Surface and Coatings Technology 383 (February 2020): 125192. http://dx.doi.org/10.1016/j.surfcoat.2019.125192.

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López González, Antonio, Pedro Pérez Borredá, and Rebeca Conde Sardón. "Fracture of a HTR-PMI cranioplastic implant after severe TBI." Child's Nervous System 31, no. 2 (July 17, 2014): 333–36. http://dx.doi.org/10.1007/s00381-014-2493-5.

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Adetchessi, A. T., G. Pech-Gourg, P. Metellus, and S. Fuentes. "Fracture précoce d’une cranioplastie en céramique macroporeuse d’hydroxyapatite." Neurochirurgie 58, no. 6 (December 2012): 382–85. http://dx.doi.org/10.1016/j.neuchi.2012.06.001.

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Mallela, Arka N., Hussam Abou-Al-Shaar, Gautam M. Nayar, Diego D. Luy, Niravkumar Barot, and Jorge A. González-Martínez. "Stereotactic Electroencephalography Implantation Through Nonautologous Cranioplasty: Proof of Concept." Operative Neurosurgery 21, no. 4 (July 22, 2021): 258–64. http://dx.doi.org/10.1093/ons/opab260.

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Abstract BACKGROUND Stereoelectroencephalography (SEEG) is an effective method to define the epileptogenic zone (EZ) in patients with medically intractable epilepsy. Typical placement requires passing and anchoring electrodes through native skull. OBJECTIVE To describe the successful placement of SEEG electrodes in patients without native bone. To the best of our knowledge, the use of SEEG in patients with nonautologous cranioplasties has not been described. METHODS We describe 3 cases in which SEEG was performed through nonautologous cranioplasty. The first is a 30-yr-old male with a titanium mesh cranioplasty following a left pterional craniotomy for aneurysm clipping. The second is a 51-yr-old female who previously underwent lesionectomy of a ganglioglioma with mesh cranioplasty and subsequent recurrence of her seizures. The third is a 31-yr-old male with a polyether ether ketone cranioplasty following decompressive hemicraniectomy for trauma. RESULTS SEEG was performed successfully in all three cases without intraoperative difficulties or complications and with excellent electroencephalogram recording and optimal localization of the seizure focus. The EZ was successfully localized in all three patients. There were no limitations related to drilling or inserting the guiding bolt/electrode through the nonautologous cranioplasties. CONCLUSION SEEG through nonautologous cranioplasties was clinically feasible, safe, and effective in our series. The presence of nonautologous bone cranioplasty should not preclude such patients from undergoing SEEG explorations.
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Mursch, Kay, and Julianne Behnke-Mursch. "Polyether Ether Ketone Cranioplasties Are Permeable to Diagnostic Ultrasound." World Neurosurgery 117 (September 2018): 142–43. http://dx.doi.org/10.1016/j.wneu.2018.06.064.

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31

Malis, Leonard I. "Titanium Mesh and Acrylic Cranioplasty." Neurosurgery 25, no. 3 (September 1, 1989): 351–55. http://dx.doi.org/10.1227/00006123-198909000-00005.

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Abstract Since June 1985 100 cranioplasties have been carried out using titanium mesh and acrylic. There have been no complications and no infections. Titanium mesh is virtually radiolucent. Titanium is nonmagnetic and is the most biocompatible metal known.
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Splavski, Bruno, Goran Lakicevic, Marko Kovacevic, and Damir Godec. "Customized alloplastic cranioplasty of large bone defects by 3D-printed prefabricated mold template after posttraumatic decompressive craniectomy: A technical note." Surgical Neurology International 13 (April 22, 2022): 169. http://dx.doi.org/10.25259/sni_1239_2021.

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Background: Manufacturing of customized three-dimensional (3D)-printed cranioplastic implant after decompressive craniectomy has been introduced to overcome the difficulties of intraoperative implant molding. The authors present and discuss the technique, which consists of the prefabrication of silicone implant mold using additive manufacturing, also known as 3D printing, and polymethyl methacrylate (PMMA) implant casting. Methods: To reconstruct a large bone defect sustained after decompressive craniectomy due to traumatic brain injury (TBI), a 3D-printed prefabricated mold template was used to create a customized PMMA implant for cranial vault repair in five consecutive patients. Results: A superb restoration of the symmetrical contours and curvature of the cranium was achieved in all patients. The outcome was clinically and cosmetically favorable in all of them. Conclusion: Customized alloplastic cranioplasty using 3D-printed prefabricated mold for casting PMMA implant is easy to perform technique for the restoration of cranial vault after a decompressive craniectomy following moderate-to-severe TBI. It is a valuable and modern technique to advance manufacturing of personalized prefabricated cranioplastic implants used for the reconstruction of large skull defects having complex geometry. It is a safe and cost-effective procedure having an excellent cosmetic outcome, which may considerably decrease expenses and time needed for cranial reconstructive surgery.
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SILVA, RAFAEL DENADAI PIGOZZI DA, CESAR AUGUSTO RAPOSO-AMARAL, MARCELO CAMPOS GUIDI, CASSIO EDUARDO RAPOSO-AMARAL, and CELSO LUIZ BUZZO. "Customized acrylic implants for reconstruction of extensive skull defects: an exception approach for selected patients." Revista do Colégio Brasileiro de Cirurgiões 44, no. 2 (April 2017): 154–62. http://dx.doi.org/10.1590/0100-69912017002008.

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ABSTRACT Objective: to present our experience in the surgical treatment of extensive skullcap defects with customized acrylic implants. Methods: we conducted a retrospective analysis of patients with extensive skull defects undergoing acrylic cranioplasties between 2004 and 2013. We carefully selected all patients and classified surgical results based on three scales (craniofacial esthetics, improvement of facial symmetry and need for additional surgery). Results: fifteen patients underwent cranioplasty with intraoperative acrylic implants, whether manually customized (46.67%) or made with prototyped three-dimensional biomodels (53.33%). There were two (13.33%) complications (one infection with implant withdrawal and one seroma). We considered the craniofacial aesthetics excellent (50%), the degree of improvement of craniofacial symmetry satisfactory (57.14%), and the overall mean of surgical results according to the need for new surgeries was 1.5±0.52. Conclusion: cranioplasties of patients with extensive skullcap defects should obey careful and predetermined criteria, both for selection and for the acrylic implant customization method.
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Quadros, Ricardo Souza, Atos Alves de Sousa, Gervásio Telles Cardoso Carvalho, and Marcos Antônio Dellaretti Filho. "Multifocal osteoclastoma of the skull: case report." Arquivos de Neuro-Psiquiatria 62, no. 1 (March 2004): 167–69. http://dx.doi.org/10.1590/s0004-282x2004000100031.

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We describe the case of a 35 years old man with a nonspecific complaint of a slow growing solid mass in the frontal region. Radiological exams evidenced two more lesions : in the superior and lateral walls of the orbit. Treated with total excision of the lesions and a cranioplastic procedure at the same act, with favorable outcome. Microscopic findings suggested giant cell tumor in the three lesions that was confirmed by imunohistochemical examination.
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Yacubian-Fernandes, Adriano, Paulo Roberto Laronga, Régis Antônio Coelho, Luis Gustavo Ducati, and Mateus Violin Silva. "Prototipagem como forma alternativa para realização de cranioplastia com metilmetacrilato: nota técnica." Arquivos de Neuro-Psiquiatria 62, no. 3b (September 2004): 865–68. http://dx.doi.org/10.1590/s0004-282x2004000500023.

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A prototipagem, método de reconstrução de segmentos do corpo humano através de programas de computação, tem sido usada na neurocirurgia para reproduzir o crânio de pacientes permitindo a programação de atos cirúrgicos e a produção de próteses para reconstruir falhas ósseas no crânio. Apresentamos dois casos de cranioplastia realizadas com o uso de próteses de acrílico construídas por prototipagem. Após 10 meses de acompanhamento, os pacientes não apresentaram sinais de infecção e apresentam bom resultado estético. As vantagens apontadas na literatura para este método (redução do tempo cirúrgico, facilidade técnica e bom resultado estético) foram observadas.
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Wyleżoł, Marek, and Piotr Frączek. "Virtual model of a protective helmet for people waiting for cranioplastic treatment." Mechanik 92, no. 1 (January 14, 2019): 46–48. http://dx.doi.org/10.17814/mechanik.2019.1.8.

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Article refers to discuss the virtual helmet model designed for people waiting for craniplasty treatment. The helmet should protect the trauma zone until surgery. It should also be easy in everyday use. The model was made using ergonomic and strength analysis. All work was supported by the CATIA v5 system.
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Persson, Johan, Benedikt Helgason, Håkan Engqvist, Stephen J. Ferguson, and Cecilia Persson. "Stiffness and strength of cranioplastic implant systems in comparison to cranial bone." Journal of Cranio-Maxillofacial Surgery 46, no. 3 (March 2018): 418–23. http://dx.doi.org/10.1016/j.jcms.2017.11.025.

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38

Amelot, A., A. Nataloni, P. François, A. R. Cook, J. P. Lejeune, M. Baroncini, P. L. Hénaux, et al. "Security and reliability of CUSTOMBONE cranioplasties: A prospective multicentric study." Neurochirurgie 67, no. 4 (July 2021): 301–9. http://dx.doi.org/10.1016/j.neuchi.2021.02.007.

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39

Klieverik, Vita M., Kai J. Miller, Kuo Sen Han, Ash Singhal, Michael Vassilyadi, Charles J. Touchette, Alexander G. Weil, and Peter A. Woerdeman. "Cranioplasties following craniectomies in children—a multicenter, retrospective cohort study." Child's Nervous System 35, no. 9 (December 15, 2018): 1473–80. http://dx.doi.org/10.1007/s00381-018-4024-2.

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40

Markman de Almeida, Marcella, Caio Atanasio de Morais Ramos, Camila Catharine Pontes Sanches, Karinne Mendes Santos, Maria Áurea de Andrade Borba, Rayana De Albuquerque Guimarães Pimentel, and Cícero Pacheco. "Craniectomia descompressiva para tratamento de hipertensão intracraniana secundária a trauma com posterior cranioplastia:." Jornal Memorial da Medicina 1, no. 2 (November 30, 2020): 1–4. http://dx.doi.org/10.37085/jmmv1.n2.2019.pp.1-4.

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A caixa craniana possui volume constante, estando sujeita a pequenas flutuações de pressão, fisiologicamente situadas entre 5-15 mmHg. Lesões secundárias ao trauma-crânio-encefálico, podem acarretar hipertensão intracraniana. O presente relato descreve o caso de uma mulher com 59 anos, atendida na unidade de trauma do Hospital da Restauração, vítima de queda de própria altura com história de rebaixamento súbito do nível de consciência, seguido de agitação e desorientação. A tomografia computadorizada mostrou hematomas subdural agudo e intraparenquimatoso, com desvio das estruturas da linha média maior que 5 mm, justificando realização de uma craniectomia descompressiva de emergência. A paciente evoluiu estável hemodinamicamente, com déficit hemiparético direito de grau II. Foi então realizada cranioplastia 20 dias após primeira intervenção, de modo a evitar Síndrome do Trefinado e suas complicações.
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41

Jasper, L. E., H. Deramond, J. M. Mathis, and S. M. Belkoff. "The effect of monomer-to-powder ratio on the material properties of cranioplastic." Bone 25, no. 2 (August 1999): 27S—29S. http://dx.doi.org/10.1016/s8756-3282(99)00129-5.

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42

Yeap, Mun-Chun, Ching-Chang Chen, Chun-Ting Chen, Zhuo-Hao Liu, Chieh-Tsai Wu, Po-Chuan Hsieh, Hong-Yi Lai, et al. "Predictive Value of Swab Cultures for Cryopreserved Flaps During Delayed Cranioplasties." World Neurosurgery 157 (January 2022): e173-e178. http://dx.doi.org/10.1016/j.wneu.2021.09.111.

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43

Niziol, Rafal, Luke Williams, and Robert Bentley. "Controversies of material: A single centre review of 432 titanium cranioplasties." British Journal of Oral and Maxillofacial Surgery 57, no. 10 (December 2019): e98. http://dx.doi.org/10.1016/j.bjoms.2019.10.284.

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44

Joaquim, Andrei Fernandes, João Paulo Mattos, Feres Chaddad Neto, Armando Lopes, and Evandro de Oliveira. "Bone flap management in neurosurgery." Revista Neurociências 17, no. 2 (January 23, 2019): 133–37. http://dx.doi.org/10.34024/rnc.2009.v17.8572.

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A remoção cirúrgica do flap ósseo em casos de craniotomia descompressiva vem sendo cada vez mais usada para o tratamento de swelling pós-traumático, doenças cerebrovasculares ou no edema cerebral pós cirurgia eletiva não responsivo ao tratamento clínico. O destino do retalho ósseo até ao seu uso para cranioplastia em tempo oportuno é motivo de controvérsia e diferentes condutas são adotadas em centros de todo o mundo. Abordamos e discutimos nesta revisão os diferentes locais de preservação do retalho ósseo (subgaleal, parede abdominal e congelamento), quando desprezá-lo e o que fazer frente à contaminação durante o ato operatório ou se infectado.
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45

Веевник, Д. П., А. И. Трутько, and А. А. Ходиченко. "Meta-Analysis of Use of Different Types of Implants in Cranioplastic Interventions in Neurosurgery." Неврология и нейрохирургия. Восточная Европа, no. 2 (May 19, 2021): 188–98. http://dx.doi.org/10.34883/pi.2021.11.2.034.

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Введение. Краниопластика является актуальным направлением в современной нейрохирургии, так как значительная часть нейрохирургических вмешательств завершается удалением костного лоскута. У пациентов с дефектами костей черепа часто имеются последствия неврологического, терапевтического и психологического характера. Восстановление целостности костей свода черепа позволяет достигнуть значимых успехов в лечебной, трудовой и социальной реабилитации пациентов.Цель. Оценка эффективности различных типов имплантов в нейрохирургии на основании послеоперационных осложнений по результатам метаанализа.Материалы и методы. Были изучены базы научно-исследовательских работ: Ovid MEDLINE / PubMed, EMBASE, Scopus, Google Scholar и Cochrane Database. Каждый тип трансплантата сравнивался с другим по наличию соответствующих осложнений с использованием программы SPSS Statistics 23.0 и программного обеспечения Microsoft Excel. Результаты метаанализа получены при помощи программного обеспечения RevMan, необходимого для создания классического систематического Кокрановского обзора. Для метаанализа отобрано 17 работ.Результаты. Установлено статистически значимое более безопасное использование PMMA по сравнению с аутографтом по частоте возникновения инфекционных осложнений. Метаанализ исследований применения нового материала на основе полиэфиркетона показал более низкие риски развития осложнений по сравнению с титановой сеткой. Не было выявлено статистически значимого эффекта, указывающего на более эффективное и безопасное применение титановой сетки по сравнению с аутологичной костью и PMMA, несмотря на меньшую частоту развития местных осложнений титанового импланта (χ2=9,35, p=0,05). Не доказана значимая эффективность применения аутокраниопластики в сравнении с аллопластическими материалами.Выводы. Результаты метаанализа позволили сделать выводы об эффективности использова-ния различных типов имплантов на основании данных исследований о послеоперационных осложнениях. Introduction. Cranioplasty is an urgent trend in modern neurosurgery, because a significant part of neurosurgical interventions is completed by the removal of a bone flap. Patients with defects of skull bones often have neurological, therapeutic and psychological consequences. Restoration of the integrity of the cranial vault bones lets to achieve a significant success in the medical, work, and social rehabilitation of patients.Purpose. To evaluate the effectiveness of various types of implants in neurosurgery on the base of postoperative complications, according to the results of meta-analysis.Materials and methods. The following research bases were studied: Ovid MEDLINE / PubMed, EMBASE, Scopus, Google Scholar, and Cochrane Database. Each graft type was compared with others for the presence of complications using the SPSS Statistics 23.0 and Microsoft Excel software. The results of meta-analysis were obtained using the RevMan software required to create the classic systematic Cochrane review; 17 papers were selected for meta-analysis.Results. A statistically significant safer use of PMMA in comparison with an autograft was found in terms of infectious complications. Meta-analysis of the studies on new material based on polyetherketone revealed lower risks of complications if compared to titanium mesh. There was no statistically significant effect indicating more effective and safe use of titanium mesh if compared to autologous bone or PMMA, despite the lower incidence of titanium implant-associated local complications (χ2=9.35, p=0.05). Significant effectiveness of autocranioplasty in comparison with alloplastic materials was not proved.Conclusions. The use of meta-analysis let to make conclusions on the effectiveness of various implants on the base of the data on postoperative complications.
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Chochaeva, A. M., Mag Sh Mustafaev, and F. R. Batirbekova. "P.107 Resectional craniotomy or primary cranioplastic in urgent surgery of cranial brain trauma." Journal of Cranio-Maxillofacial Surgery 34 (September 2006): 158–59. http://dx.doi.org/10.1016/s1010-5182(06)60614-8.

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47

Rocque, Brandon G., Kaushik Amancherla, Sean M. Lew, and Sandi Lam. "Outcomes of cranioplasty following decompressive craniectomy in the pediatric population." Journal of Neurosurgery: Pediatrics 12, no. 2 (August 2013): 120–25. http://dx.doi.org/10.3171/2013.4.peds12605.

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Cranioplasty is routinely performed following decompressive craniectomy in both adult and pediatric populations. In adults, this procedure is associated with higher rates of complications than is elective cranial surgery. This study is a review of the literature describing risk factors for complications after cranioplasty surgery in pediatric patients. A systematic search of PubMed, Cochrane, and SCOPUS databases was undertaken. Articles were selected based on their titles and abstracts. Only studies that focused on a pediatric population were included; case reports were excluded. Studies in which the authors assessed bone flap storage method, timing of cranioplasty, material used (synthetic vs autogenous), skull defect size, and/or complication rates (bone resorption and surgical site infection) were selected for further analysis. Eleven studies that included a total of 441 cranioplasties performed in the pediatric population are included in this review. The findings are as follows: 1) Based on analysis of pooled data, using cryopreserved bone flaps during cranioplasty may lead to a higher rate of bone resorption and lower rate of infection than using bone flaps stored at room temperature. 2) In 3 of 4 articles describing the effect of time between craniectomy and cranioplasty on complication rate, the authors found no significant effect, while in 1 the authors found that the incidence of bone resorption was significantly lower in children who had undergone early cranioplasty. Pooling of data was not possible for this analysis. 3) There are insufficient data to assess the effect of cranioplasty material on complication rate when considering only cranioplasties performed to repair decompressive craniectomy defects. However, when considering cranioplasties performed for any indication, those in which freshly harvested autograft is used may have a lower rate of resorption than those in which stored autograft is used. 4) There is no appreciable effect of craniectomy defect size or patient age on complication rate. There is a paucity of articles describing outcomes and complications following cranioplasty in children and adolescents. However, based on the studies examined in this systematic review, there are reasons to suspect that method of flap preservation, timing of surgery, and material used may be significant. Larger prospective and retrospective studies are needed to shed more light on this important issue.
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Sandler, Adam L., Arundhati Biswas, and James Tait Goodrich. "The Reverend Russell H. Conwell, W. Wayne Babcock, and the “soup bone” cranioplasties of 1915." Neurosurgical Focus 36, no. 4 (April 2014): E21. http://dx.doi.org/10.3171/2014.2.focus13573.

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In 1915, faced with 2 patients with large skull defects, W. Wayne Babcock, an obstetrician-gynecologist-turned-general surgeon, operating in a modest North Philadelphia hospital, did something extraordinary: he went to the hospital kitchen to look for a cranial graft. Based heavily on archival and other primary sources, the authors tell the remarkable tale of the “soup bone” cranioplasties of the Samaritan Hospital and place these operations within the context of the early modern American hospital.
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Jiang, Ying, Yun-Kun Wang, and Ming-Kun Yu. "Spontaneous fracture of cranioplastic titanium implants without head trauma in an adult: A case report." International Journal of Surgery Case Reports 24 (2016): 50–53. http://dx.doi.org/10.1016/j.ijscr.2016.04.039.

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50

Gordon, Chad R., Mark Fisher, Jason Liauw, Ioan Lina, Varun Puvanesarajah, Srinivas Susarla, Alexander Coon, et al. "Multidisciplinary Approach for Improved Outcomes in Secondary Cranial Reconstruction: Introducing the Pericranial-Onlay Cranioplasty Technique." Operative Neurosurgery 10, no. 2 (January 27, 2014): 179–90. http://dx.doi.org/10.1227/neu.0000000000000296.

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AbstractBACKGROUND:Although materials for secondary cranial reconstruction have evolved with time, the overall approach in terms of bone flap/implant reconstruction after necessary delay has remained constant.OBJECTIVE:To present our cases series of 50 consecutive secondary cranial reconstruction patients and to describe a multidisciplinary cranioplasty approach developed to reduce morbidity, to minimize infection, and to improve aesthetic appearance.METHODS:Standard technique teaches us to place the bone flap and/or alloplastic implant directly over the dura or dural protectant after scalp flap re-elevation. However, this procedure is fraught with high complication rates, including infection. While raising the previously incised scalp flap overlying the full-thickness calvarial defect, the dissection is performed within the loose areolar tissue plane beneath the galea aponeurosis, thus leaving vascularized pericranium intact over the dura.RESULTS:A total of 50 consecutive patients were treated by the senior author encompassing 46 cranioplasties using the pericranial-onlay approach, along with 4 isolated temporal soft tissue reconstructions with liquid poly-methyl-methacrylate. Of the 46 cranioplasties (> 5 cm2), only 1 autologous bone flap developed deep infection necessitating bone flap removal (1 of 46, 2.17%; 95% confidence interval, 0.003-11.3). None of the alloplastic custom implants placed have developed any infection requiring removal.CONCLUSION:This multidisciplinary approach illustrated in our case series, including our “pericranial-onlay” technique described here for the first time, has the potential to improve patient outcomes, to decrease perioperative morbidity, and to minimize costs associated with postoperative infections after secondary cranial reconstruction.
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