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1

Hu, Guanglong, Yiheng Wang, Yan Wang, Shuqi Zheng, Wenxuan Dong, and Ningguang Dong. "New Insight into the Phylogeny and Taxonomy of Cultivated and Related Species of Crataegus in China, Based on Complete Chloroplast Genome Sequencing." Horticulturae 7, no. 9 (2021): 301. http://dx.doi.org/10.3390/horticulturae7090301.

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Hawthorns (Crataegus L.) are one of the most important processing and table fruits in China, due to their medicinal properties and health benefits. However, the interspecific relationships and evolution history of cultivated Crataegus in China remain unclear. Our previously published data showed C. bretschneideri may be derived from the hybridization of C. pinnatifida with C. maximowiczii, and that introgression occurs between C. hupehensis, C. pinnatifida, and C. pinnatifida var. major. In the present study, chloroplast sequences were used to further elucidate the phylogenetic relationships of cultivated Crataegus native to China. The chloroplast genomes of three cultivated species and one related species of Crataegus were sequenced for comparative and phylogenetic analyses. The four chloroplast genomes of Crataegus exhibited typical quadripartite structures and ranged from 159,607 bp (C. bretschneideri) to 159,875 bp (C. maximowiczii) in length. The plastomes of the four species contained 113 genes consisting of 79 protein-coding genes, 30 tRNA genes, and 4 rRNA genes. Six hypervariable regions (ndhC-trnV(UAC)-trnM(CAU), ndhA, atpH-atpI, ndhF, trnR(UCU)-atpA, and ndhF-rpl32), 196 repeats, and a total of 386 simple sequence repeats were detected as potential variability makers for species identification and population genetic studies. In the phylogenomic analyses, we also compared the entire chloroplast genomes of three published Crataegus species: C. hupehensis (MW201730.1), C. pinnatifida (MN102356.1), and C. marshallii (MK920293.1). Our phylogenetic analyses grouped the seven Crataegus taxa into two main clusters. One cluster included C. bretschneideri, C. maximowiczii, and C. marshallii, whereas the other included C. hupehensis, C. pinnatifida, and C. pinnatifida var. major. Taken together, our findings indicate that C. maximowiczii is the maternal origin of C. bretschneideri. This work provides further evidence of introgression between C. hupehensis, C. pinnatifida, and C. pinnatifida var. major, and suggests that C. pinnatifida var. major might have been artificially selected and domesticated from hybrid populations, rather than evolved from C. pinnatifida.
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2

LIU, TENGTENG, and HU WANG. "Bucculatrix crataega sp. nov. (Lepidoptera: Bucculatricidae), a leaf miner on Crataegus, representing the first formally named species of the family from mainland China." Zootaxa 4545, no. 4 (2019): 578. http://dx.doi.org/10.11646/zootaxa.4545.4.8.

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A new leaf-mining species of the genus Bucculatrix Zeller, 1839, B. crataega Liu, sp. nov., feeding on Crataegus pinnatifida Bunge is described herein, representing the first formally named species of Bucculatricidae from mainland China. Adult and genitalia of both sexes are described and illustrated. Host plant, leaf mine and cocoon are also illustrated. DNA barcode analysis supports the separation of B. crataega from related species.
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3

Budantsev, Andrey L'vovich, Lidiya Markovna Belenovskaya, and Natal'ya Valentinovna Bityukova. "COMPONENT COMPOSITION AND BIOLOGICAL ACTIVITY OF CRATAEGUS PINNATIFIDA (ROSACEAE) (REVIEW)." chemistry of plant raw material, no. 4 (December 21, 2020): 31–58. http://dx.doi.org/10.14258/jcprm.2020046612.

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Information on the diversity of the composition of terpenoids, phenolic compounds (phenylpropanoids, lignans, flavonoids) and other groups of secondary metabolites of Crataegus pinnatifida, published in the world literature over the past decades, is presented. Structural formulas are also indicated for new components isolated from C. pinnatifida. Among the new terpenoids of the leaves, fruits, and seeds of C. pinnatifida, mono- and sesquiterpenic glycosides (shanyesides, pinnatifidanosides, etc.), as well as triterpenic acids of the oleanan series, predominate. Among the phenolic compounds in the leaves and seeds, new biphenyl glycosides (shanyenosides), derivatives of cinnamaldehyde (crataegusoids), crataegusanoids and other phenylpropanoids were found. The most diverse in various parts of C. pinnatifida, especially in the seeds, are lignans of various types of structure, in particular sesquilignan glycosides, as well as new lignans (pinnatifidanins, pinnatifidaninsides, neolignans of the dibenzofuran series and other substances). In addition to these groups, new flavonoids, flavanocoumarins, and naphthoquinones were found in leaves, flowers, fruits, and seeds. The results of pharmacological studies showing the presence of cytotoxic, anti-inflammatory, antioxidant, antidiabetic, hypocholesterolemic, thrombolytic, neuroprotective, antibacterial and other types of biological activity found in extracts, their fractions, as well as individual compounds of various organs and parts of C. pinnatifida are presented.
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4

Chen, San-Yuan, Ru-Hsiou Teng, Meilin Wang, et al. "Rhodiolae Kirliowii Radix et Rhizoma and Crataegus pinnatifida Fructus Extracts Effectively Inhibit BK Virus and JC Virus Infection of Host Cells." Evidence-Based Complementary and Alternative Medicine 2017 (2017): 1–11. http://dx.doi.org/10.1155/2017/5620867.

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The human polyomaviruses BK (BKPyV) and JC (JCPyV) are ubiquitous pathogens long associated with severe disease in immunocompromised individuals. BKPyV causes polyomavirus-associated nephropathy and hemorrhagic cystitis, whereas JCPyV is the causative agent of the fatal demyelinating disease progressive multifocal leukoencephalopathy. No effective therapies targeting these viruses are currently available. The goal of this study was to identify Chinese medicinal herbs with antiviral activity against BKPyV and JCPyV. We screened extracts of Chinese medicinal herbs for the ability to inhibit hemagglutination by BKPyV and JCPyV virus-like particles (VLPs) and the ability to inhibit BKPyV and JCPyV binding and infection of host cells. Two of the 40 herbal extracts screened, Rhodiolae Kirliowii Radix et Rhizoma and Crataegus pinnatifida Fructus, had hemagglutination inhibition activity on BKPyV and JCPyV VLPs and further inhibited infection of the cells by BKPyV and JCPyV, as evidenced by reduced expression of viral proteins in BKPyV-infected and JCPyV-infected cells after treatment with Rhodiolae Kirliowii Radix et Rhizoma or Crataegus pinnatifida Fructus extract. The results in this work show that both Rhodiolae Kirliowii Radix et Rhizoma and Crataegus pinnatifida Fructus may be sources of potential antiviral compounds for treating BKPyV and JCPyV infections.
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5

Gao, Pin-Yi, Ling-Zhi Li, Ke-Chun Liu, et al. "Natural terpenoid glycosides with in vitro/vivo antithrombotic profiles from the leaves of Crataegus pinnatifida." RSC Adv. 7, no. 76 (2017): 48466–74. http://dx.doi.org/10.1039/c7ra10768d.

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Two norditerpenoids (1–2) with unique carbon skeletons, four sesquiterpenoids (3–6) and nine nor-sesquiterpenoids (7–15) were isolated from the leaves of Crataegus pinnatifida and evaluated as possessing antithrombotic activities in vitro/vivo.
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6

Wu, Jiaqi, Wei Peng, Rongxin Qin, and Hong Zhou. "Crataegus pinnatifida: Chemical Constituents, Pharmacology, and Potential Applications." Molecules 19, no. 2 (2014): 1685–712. http://dx.doi.org/10.3390/molecules19021685.

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7

Luo, Meng, Jiao-Yang Hu, Zhuo-Yue Song, et al. "Optimization of ultrasound-assisted extraction (UAE) of phenolic compounds from Crataegus pinnatifida leaves and evaluation of antioxidant activities of extracts." RSC Advances 5, no. 83 (2015): 67532–40. http://dx.doi.org/10.1039/c5ra07445b.

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In this study, a highly efficient BBD–RSM optimized ultrasound-assisted extraction combined with HPLC method has been established for the simultaneous extraction and determination of CA, VG, VR, ORT, RT, VIT and HYP from Crataegus pinnatifida leaves.
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8

Kim, Han-Soo, Min-A. Kim, and Seong-Ho Jang. "Improvement Effect of Hyperlipidemia by Wild Haw (Crataegus pinnatifida BUNGE)." Journal of Environmental Science International 23, no. 5 (2014): 787–92. http://dx.doi.org/10.5322/jesi.2014.5.787.

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9

Duan, Yishan, Min-A. Kim, Jong-Hwan Seong, Hun-Sik Chung, and Han-Soo Kim. "Antioxidative activities of various solvent extracts from haw (Crataegus pinnatifida Bunge)." Korean Journal of Food Preservation 21, no. 2 (2014): 246–53. http://dx.doi.org/10.11002/kjfp.2014.21.2.246.

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10

Duan, Yishan, Min-A. Kim, Han-Soo Kim, et al. "Effects of Feral Haw (Crataegus pinnatifida BUNGE) Seed Extracts on the Antioxidant Activities." Journal of Life Science 24, no. 4 (2014): 386–92. http://dx.doi.org/10.5352/jls.2014.24.4.386.

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11

Song, Shao-Jiang, Ling-Zhi Li, Pin-Yi Gao, Ying Peng, Jing-Yu Yang, and Chun-Fu Wu. "Terpenoids and hexenes from the leaves of Crataegus pinnatifida." Food Chemistry 129, no. 3 (2011): 933–39. http://dx.doi.org/10.1016/j.foodchem.2011.05.049.

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12

Chu, Wanchun, Pinyi Gao, and Lingzhi Li. "Chemical constituents from the leaves of Crataegus pinnatifida Bge." Biochemical Systematics and Ecology 86 (October 2019): 103923. http://dx.doi.org/10.1016/j.bse.2019.103923.

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13

Chang, Chi-Sen, Yuh-Chiang Shen, Chi-Wen Juan, Chia-Lin Chang, and Po-Kai Lin. "Protective Effects of Crataegus pinnatifida Extracts and Crataegolic Acid Against Neurotoxicity of Paraquat in PC12 Cells." Current Topics in Nutraceutical Research 20, no. 1 (2021): 76–83. http://dx.doi.org/10.37290/ctnr2641-452x.20:76-83.

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The neuroprotective mechanisms of Crataegus pinnatifida extracts and crataegolic acid were studied using paraquat induced cytotoxicity in PC12 cells. C. pinnatifida extracts were prepared using hexane, ethyl acetate, and 95% ethanol. Additionally, crataegolic acid (also known as maslinic acid) was found in C. pinnatifida extracts. Assessment methods included the examinations of cytotoxicity, intracellular reactive oxygen species and calcium changes, activity of caspase-3 and α-synuclein, apoptotic cell death, and the expression levels of the B-cell lymphoma 2 (Bcl-2) and BCL2-associated X (Bax) proteins to investigate the neuroprotective mechanisms of C. pinnatifida extracts and its active component, crataegolic acid. The three extracts and crataegolic acid exhibited potent neuroprotective actions against paraquat induced PC12 cell apoptosis at 5–20µg/mL and 80–100µM concentrations, respectively. The key protective mechanisms included decreasing cell apoptosis, upregulating Bcl-2 protein levels, and downregulating Bax protein levels. The 95% ethanol extract also decreased paraquat induced reactive oxygen species production, calcium overloading, and caspase-3 and α-synuclein activities. The beneficial effects of these extracts could be explained by the active component, crataegolic acid that also inhibited paraquat-induced apoptosis through the suppression of reactive oxygen species generation and the caspase-3 signaling pathway.
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14

Luo, Meng, Xin Ruan, Jiao-Yang Hu, et al. "Microwave-assisted Acid Hydrolysis to Produce Vitexin from Crataegus pinnatifida Leaves and its Angiogenic Activity." Natural Product Communications 12, no. 12 (2017): 1934578X1701201. http://dx.doi.org/10.1177/1934578x1701201214.

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In this study, microwave-assisted acid hydrolysis (MAAH) to obtain vitexin (VIT) from Crataegus pinnatifida leaves was optimized. The single factor experiment was applied to optimize the operating parameters of MAAH. The 1,1-diphenyl-2-picrylhydrazyl (DPPH) radical scavenging assay and ferric reducing ability of plasma (FRAP) were performed to evaluate the antioxidant activity of extract. The results showed that the optimum parameters of dealing with 1 g sample were 2.0 M hydrochloric acid concentration, 40 min microwave irradiation time, 1:10 solid–liquid ratio, 50% ethanol concentration, 70°C microwave extraction temperature and 600 W microwave power. The yields of VIT were 2.62 mg/g under the optimum conditions. The C. pinnatifida extracted by MAAH exhibited more antioxidant activity than extracted by microwave-assisted extraction (MAE). The number of vessels in chick chorioallantoic membrane indicated that C. pinnatifida leaves could promote angiogenesis. These findings suggested that MAAH provides an efficient technique to produce VIT.
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15

Kim, Han-Soo, Min-A. Kim, and Seong-Ho Jang. "Influences of Korean Haw (Crataegus pinnatifida BUNGE) on Lipid Concentration in Hypercholesterolemia." Journal of Environmental Science International 23, no. 5 (2014): 793–800. http://dx.doi.org/10.5322/jesi.2014.5.793.

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16

LI, Ling-Zhi, Ying PENG, Chao NIU, et al. "Isolation of cytotoxic compounds from the seeds of Crataegus pinnatifida." Chinese Journal of Natural Medicines 11, no. 4 (2013): 411–14. http://dx.doi.org/10.1016/s1875-5364(13)60061-8.

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17

LI, Ling-Zhi, Ying PENG, Chao NIU, et al. "Isolation of cytotoxic compounds from the seeds of Crataegus pinnatifida." Chinese Journal of Natural Medicines 11, no. 4 (2014): 411–14. http://dx.doi.org/10.3724/sp.j.1009.2013.00411.

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18

Zhou, Chen-Chen, Xiao-Xiao Huang, Pin-Yi Gao, et al. "Two new compounds from Crataegus pinnatifida and their antithrombotic activities." Journal of Asian Natural Products Research 16, no. 2 (2013): 169–74. http://dx.doi.org/10.1080/10286020.2013.848429.

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19

Liu, W., G. Chen, and T. Cui. "Determination of Flavones in Crataegus pinnatifida by Capillary Zone Electrophoresis." Journal of Chromatographic Science 41, no. 2 (2003): 87–91. http://dx.doi.org/10.1093/chromsci/41.2.87.

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20

Gao, Pin-Yi, Ling-Zhi Li, Ying Peng, et al. "Monoterpene and lignan glycosides in the leaves of Crataegus pinnatifida." Biochemical Systematics and Ecology 38, no. 5 (2010): 988–92. http://dx.doi.org/10.1016/j.bse.2010.09.010.

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21

Huang, Xiao-Xiao, Dong-Dong Guo, Ling-Zhi Li, et al. "Monoterpene and sesquilignan compounds from the leaves of Crataegus pinnatifida." Biochemical Systematics and Ecology 48 (June 2013): 1–5. http://dx.doi.org/10.1016/j.bse.2012.12.001.

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22

Kim, Han-Soo, Yishan Duan, Min-A. Kim, and Seong-Ho Jang. "Contents of Antioxidative Components from Pulpy and Seed in Wild Haw (Crataegus pinnatifida BUNGE)." Journal of Environmental Science International 23, no. 11 (2014): 1791–99. http://dx.doi.org/10.5322/jesi.2014.23.11.1791.

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Kim, Min-A., Yishan Duan, Jong-Hwan Seong, Hun-Sik Chung, and Han-Soo Kim. "Antioxidative Activity of Feral Haw (Crataegus pinnatifida BUNGE) Seed Extracts Using Various Solvents." Korean journal of food and cookery science 30, no. 1 (2014): 33–40. http://dx.doi.org/10.9724/kfcs.2014.30.1.033.

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24

Kazuma, Kohei, Yuka Isobe, Haruka Asahina, Tatsuo Nehira, Motoyoshi Satake, and Katsuhiro Konno. "Crataegusins A and B, New Flavanocoumarins from the Dried Fruits of Crataegus pinnatifida var. major (Rosaceae)." Natural Product Communications 11, no. 7 (2016): 1934578X1601100. http://dx.doi.org/10.1177/1934578x1601100724.

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Crataegusins A (1) and B (2), new flavanocoumarins, were isolated from the crude drug Crataegus Fructus, i.e., the dried fruits of Crataegus pinnatifida var. major. Their structures were determined by spectroscopic methods. They were unique in terms of carrying a 3-(or 4-)substituted coumarin substructure while a flavanocoumarin generally does not carry any substituents in the 2-pyron ring. They showed a significant DPPH reducing activity compared with epicatechin. Their production would be biosynthetically regulated considering the results of an LC-MS analysis of the dried and fresh fruits, fruit skin, hypanthia, and leaves. Their structures led the authors to consider a hypothetical general biosynthetic pathway of the flavanocoumarins, to which a flavan-3-ol is converted through a Michael addition and successive oxidative decarboxylation or dehydration pathway.
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Nam, Sang-Myeoung, Il-Jun Kang, and Mee-Hye Shin. "Anti-diabetic and Anti-oxidative activities of Extracts from Crataegus pinnatifida." Journal of the East Asian Society of Dietary Life 25, no. 2 (2015): 270. http://dx.doi.org/10.17495/easdl.2015.4.25.2.270.

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26

Wen, Lingrong, Xingbo Guo, Rui Hai Liu, Lijun You, Arshad Mehmood Abbasi, and Xiong Fu. "Phenolic contents and cellular antioxidant activity of Chinese hawthorn “Crataegus pinnatifida”." Food Chemistry 186 (November 2015): 54–62. http://dx.doi.org/10.1016/j.foodchem.2015.03.017.

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27

Chang, C. L., H. S. Chen, Y. C. Shen, G. H. Lai, P. K. Lin, and C. M. Wang. "Phytochemical composition, antioxidant activity and neuroprotective effect of Crataegus pinnatifida fruit." South African Journal of Botany 88 (September 2013): 432–37. http://dx.doi.org/10.1016/j.sajb.2013.08.017.

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Shin, Heon-Sub, Jung-Min Lee, Sang-Yong Park, Jung-Eun Yang, Ju-Han Kim, and Tae-Hoo Yi. "Hair Growth Activity of Crataegus pinnatifida on C57BL/6 Mouse Model." Phytotherapy Research 27, no. 9 (2012): 1352–57. http://dx.doi.org/10.1002/ptr.4870.

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Cheng, Zhuo-Yang, Li-Li Lou, Pei-Yuan Yang, et al. "Seven new neuroprotective sesquineolignans isolated from the seeds of Crataegus pinnatifida." Fitoterapia 133 (March 2019): 225–30. http://dx.doi.org/10.1016/j.fitote.2019.01.008.

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30

Zhao, Peng, Shuang Qiu, Zi-Lin Hou, et al. "Sesquineolignans derivatives with neuroprotective activity from the fruits of Crataegus pinnatifida." Fitoterapia 143 (June 2020): 104591. http://dx.doi.org/10.1016/j.fitote.2020.104591.

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Moon, Hyung-In, Tae-im Kim, Hyun-Soo Cho, and Eung Kweon Kim. "Identification of potential and selective collagenase, gelatinase inhibitors from Crataegus pinnatifida." Bioorganic & Medicinal Chemistry Letters 20, no. 3 (2010): 991–93. http://dx.doi.org/10.1016/j.bmcl.2009.12.059.

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Chen, Xing, Hongbing Zhang, Wenqing Du, et al. "Comparison of different extraction methods for polysaccharides from Crataegus pinnatifida Bunge." International Journal of Biological Macromolecules 150 (May 2020): 1011–19. http://dx.doi.org/10.1016/j.ijbiomac.2019.11.056.

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Song, Shao-Jiang, Ling-Zhi Li, Pin-Yi Gao, et al. "Isolation of Antithrombotic Phenolic Compounds from the Leaves of Crataegus pinnatifida." Planta Medica 78, no. 18 (2012): 1967–71. http://dx.doi.org/10.1055/s-0032-1327877.

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Huang, Xiao-Xiao, Chen-Chen Zhou, Ling-Zhi Li, et al. "Cytotoxic and antioxidant dihydrobenzofuran neolignans from the seeds of Crataegus pinnatifida." Fitoterapia 91 (December 2013): 217–23. http://dx.doi.org/10.1016/j.fitote.2013.09.011.

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Goncharova, Oxana A., and Olesya Evgenievna Zotova. "Complex Assessment of the Viability and Decorativeness of Species of the Genus Crataegus L. in the Kola North Conditions." Izvestiya of Saratov University. New Series. Series: Chemistry. Biology. Ecology 20, no. 4 (2020): 438–44. http://dx.doi.org/10.18500/1816-9775-2020-20-4-438-444.

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The paper presents the results of a comprehensive assessment of the viability and decorativeness of 20 samples of 17 taxa of the genus Crataegus L. when introduced into the Kola North. The study is one of the stages of a systematic description of the adaptive state of plants of the genus Crataegus when introduced into the conditions of the Far North. The main part of the studied samples are highly decorative quite viable plants that have high winter hardiness, maintain their growth shape, are able to produce germinating seeds, and have attractive inflorescences and fruits. C. chlorosarca, C. chlorosarca f. pyramidalica, C. cuneata, C. dahurica, C. douglasii, C. flabellata, C. laevigata, C. maximoviczii, C. pinnatifida, C. sanguinea, C. x schroederi. C. arnoldiana, C. canadensis and C. foetida are nonviable and undecorative plants. For the introduction of promising species of the genus Crataegus into the landscaping of cities of the Kola Peninsula, preliminary testing is required. Maintaining a highly decorative state is possible while observing the care of woody plants.
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Jurikova, Tunde, Jiri Sochor, Otakar Rop, et al. "Polyphenolic Profile and Biological Activity of Chinese Hawthorn (Crataegus pinnatifida BUNGE) Fruits." Molecules 17, no. 12 (2012): 14490–509. http://dx.doi.org/10.3390/molecules171214490.

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Zhang, Pei-Cheng, and Sui-Xu Xu. "Flavonoid ketohexosefuranosides from the leaves of Crataegus pinnatifida Bge. var. major N.E.Br." Phytochemistry 57, no. 8 (2001): 1249–53. http://dx.doi.org/10.1016/s0031-9422(01)00170-4.

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Huang, Xiao-Xiao, Qing-Bo Liu, Jie Wu, et al. "Antioxidant and Tyrosinase Inhibitory Effects of Neolignan Glycosides from Crataegus pinnatifida Seeds." Planta Medica 80, no. 18 (2014): 1732–38. http://dx.doi.org/10.1055/s-0034-1383253.

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Guo, Rui, Tianming Lv, Fengying Han, et al. "New norlignan enantiomers from the fruit of Crataegus pinnatifida with neuroprotective activities." Chinese Chemical Letters 31, no. 5 (2020): 1254–58. http://dx.doi.org/10.1016/j.cclet.2019.09.042.

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40

Li, Ling-Zhi, Pin-Yi Gao, Shao-Jiang Song, et al. "Monoterpenes and flavones from the leaves of Crataegus pinnatifida with anticoagulant activities." Journal of Functional Foods 12 (January 2015): 237–45. http://dx.doi.org/10.1016/j.jff.2014.11.012.

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Mokhtar, Mokhtar Mohamedalamin, Jianfeng Li, Zhiping Du, and Fangqin Cheng. "Preliminary Phytochemical Analysis and Biological Evaluation of Some Medicinal Chinese Plant Extracts against Tribolium castaneum." Sains Malaysiana 50, no. 8 (2021): 2283–92. http://dx.doi.org/10.17576/jsm-2021-5008-12.

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Application of botanical pesticides is a new trend in pest control nowadays as an environmentally safe alternative measures for synthetic chemicals. Hence, this study was aimed to analyze the phytochemical constituents of four medicinal Chinese plants, namely Lonicera maackii, Platycladus orientalis, Viburnum opulus, and Crataegus pinnatifida, and to investigate the insecticidal potentialities of leaves extracts of these plants against Tribolium castaneum. The research was carried out under laboratory conditions, at the Institute of Resources and Environmental Engineering, Shanxi University, China. Ethyl acetate, methanol and water extracts of the plant leaves were tested at different concentrations (5, 2.5, and 1.25% w/v). Yields of extracting materials, mortality and repellent effects were the important parameters evaluated. The phytochemical screening showed the presence of alkaloids, saponins, tannins, flavonoid, and terpenoids in C. pinnatifida, but the other plants contain some of these compounds. The highest ethyl acetate extract concentration (5%) of V. opulus and C. pinnatifida obtained the best mortality means (5.00±0.41 and 4.75±0.25a, respectively), compared to the other treatments, but without significant differences from the middle concentration (2.5%) of both extracts. In repellency test, L. maackii methanol achieved the highest repellency percentage (91.38%). The findings proved that ethyl acetate extract of V. opulus and C. pinnatifida are the best insecticidal treatment, whereas methanol extract of L. maackii is the best repellent effect, against T. castaneum. These three plants require additional studies to be assessed as a component in pest management of store pests.
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Kim, Han-Soo, Min-A. Kim, Yishan Duan, et al. "Influences of Wild Haw (Crataegus pinnatifida BUNGE) on Lowering BUN and Creatinine Concentrations in Dyslipidemia." Journal of Environmental Science International 23, no. 6 (2014): 1029–35. http://dx.doi.org/10.5322/jesi.2014.23.6.1029.

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Zhang, M., Y. L. Zhang, Z. Q. Sun, et al. "First Report of Botrytis cinerea Causing Fruit Rot of Crataegus pinnatifida in China." Plant Disease 102, no. 8 (2018): 1667. http://dx.doi.org/10.1094/pdis-02-18-0223-pdn.

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Kim, Sea-Hyun, Andosung Lee, Daebong Kang, Hae Yun Kwon, Youngki Park, and Moon Sup Kim. "Analysis of floral nectar characteristics of Korean and Chinese hawthorns (Crataegus pinnatifida Bunge)." Journal of Apicultural Research 57, no. 1 (2017): 119–28. http://dx.doi.org/10.1080/00218839.2017.1357942.

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He, Shui-Lian, Jing Xie, Yang Yang, and Yang Tian. "Chloroplast genome for Crataegus pinnatifida (Rosaceae) and phylogenetic analyses with its coordinal species." Mitochondrial DNA Part B 5, no. 3 (2020): 2097–98. http://dx.doi.org/10.1080/23802359.2019.1667273.

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Zhao, Peng, Rui Guo, Yang-Yang Zhang, et al. "Phenylpropanoid and dibenzofuran derivatives from Crataegus pinnatifida with antiproliferative activities on hepatoma cells." Bioorganic Chemistry 93 (December 2019): 103354. http://dx.doi.org/10.1016/j.bioorg.2019.103354.

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Huang, Xiao-Xiao, Chen-Chen Zhou, Ling-Zhi Li, et al. "The cytotoxicity of 8-O-4′ neolignans from the seeds of Crataegus pinnatifida." Bioorganic & Medicinal Chemistry Letters 23, no. 20 (2013): 5599–604. http://dx.doi.org/10.1016/j.bmcl.2013.08.045.

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Guo, Ciliang, Yeqing Wang, Shihai Zhang, et al. "Crataegus pinnatifida polysaccharide alleviates colitis via modulation of gut microbiota and SCFAs metabolism." International Journal of Biological Macromolecules 181 (June 2021): 357–68. http://dx.doi.org/10.1016/j.ijbiomac.2021.03.137.

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Khokhlova, K. O., O. A. Zdoryk, N. V. Sydora, and V. I. Shatrovska. "Chromatographic Profiles Analysis of Fruits of Crataegus L. Genus by High-Performance Thin-Layer Chromatography." European Pharmaceutical Journal 66, no. 2 (2019): 45–51. http://dx.doi.org/10.2478/afpuc-2019-0020.

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Abstract:
Abstract It was known that hawthorn - Crataegus L. is a polymorphic genus. Two hawthorn species and their hybrids are included in the European Pharmacopoeia, twelve – in Ukrainian pharmacopoeia. Determination of chromatographic profiles of hawthorn fruits species native to Ukraine and other countries that are non-pharmacopoeial, but have sufficient plant raw material base, is essential for quality control of drugs. Aim. To analyze and compare the chromatographic profiles of fruits of 23 Crataegus L. species on phenolic compounds, evaluated by means of high-performance thin-layer chromatography procedure (HPTLC), and determine the specific features of chromatographic fingerprints. Materials and Methods. A total of 39 samples of fruits of 23 hawthorn species that are native to Europe, Asia and North America, such as Crataegus monogyna, C. laevigata/C. oxyacantha, C. leiomonogyna, C. curvisepala, C. pseudokyrtostyla, C. fallacina, C. subrotunda, C. ambigua, C. pentagyna, C. sanguinea, C. chlorosarca, C. almaatensis, C.pseudoheterophylla subsp. turkestanica, C. pinnatifida, C. pentagyna subsp. pseudomelanocarpa, C. punctata, C. pringlei, C. festiva, C. douglasii, C. holmesiana, C. submollis, C. flabellata, C. canadensis were investigated. The analysis has been done following the TLC method from European Pharmacopeia modified into HPTLC, using automated HPTLC herbal system (CAMAG, Switzerland). The results have shown that chromatographic profiles of phenolic constituents of nine Crataegus L. species of Europe, both pharmacopoeial and non-pharmacopoeial, were quite similar, despite the significant morphological distinctions. The chromatographical profiles of three species of Asia were similar to the pharmacopoeial species; three other species looked different and had specific marker zones. In addition, eight Crataegus L. species of North America had specific markers helping for discriminative analysis from pharmacopoeial species. Conclusion. The findings could help to identify the possible adulterations and prevent the falsification of finished products. The results will be taken into consideration during revision of the Ukrainian national pharmacopoeial monograph for hawthorn fruits.
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Kim, Han-Soo, Min-A. Kim, Yishan Duan, Seong-Ho Jang, Won-Ki Lee, and Jae-Young Ryu. "Effects of Haw (Crataegus pinnatifida BUNGE) on Relaxation in the Lipid Components and Blood Glucose of Lipid Metabolism Syndrome." Journal of Environmental Science International 23, no. 6 (2014): 1021–27. http://dx.doi.org/10.5322/jesi.2014.23.6.1021.

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