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1

Burri, Josef, and Bernhard Uehleke. "Tinospora crispa – Booraphed." Zeitschrift für Phytotherapie 40, no. 04 (2019): 170–71. http://dx.doi.org/10.1055/a-0986-8596.

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2

Maroyi, Alfred. "EUCLEA CRISPA: REVIEW OF ITS BOTANY, ETHNOMEDICINAL USES, AND PHARMACOLOGICAL PROPERTIES." Asian Journal of Pharmaceutical and Clinical Research 11, no. 10 (2018): 5. http://dx.doi.org/10.22159/ajpcr.2018.v11i10.25146.

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Euclea crispa is widely used as herbal medicine in southern Africa. This study was aimed at reviewing the botany, ethnomedicinal uses, and validated pharmacological properties of E. crispa. The literature search for information on ethnomedicinal uses and pharmacological activities of E. crispa was undertaken using databases such as web of science, BMC, science direct, elsevier, scopus, PubMed, and scielo. Other relevant literature sources included books, book chapters, websites, theses, conference papers, and other scientific publications. The extensive literature survey revealed that the bark, fruits, leaves, and roots of E. crispa are commonly used as herbal medicines for wounds, constipation, cough, stomach disorders, epilepsy, rheumatism, and diabetes. Pharmacological studies on E. crispa indicate that the species has amyloid β-peptide lowering effects, antibacterial, antidiarrheal, antifungal, and cell membrane disruption activities. E. crispa should be subjected to further scientific evaluations aimed at elucidating its chemical, pharmacological, and toxicological properties. Such detailed research should also include experimental animal studies, randomized clinical trials, and target-organ toxicity studies involving E. crispa extracts and its derivatives.
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3

Ceñal, Juan P., Oscar S. Giordano, Pedro C. Rossomando, and Carlos E. Tonn. "Neoclerodane Diterpenes fromBaccharis crispa." Journal of Natural Products 60, no. 5 (1997): 490–92. http://dx.doi.org/10.1021/np970003y.

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4

Nguyen, Tuan Pham, Lam Hong Bang, Tran Thi Bao Nguyen, and Tu Pham Nguyen. "BIOACTIVE COMPOUNDS ANALYSIS AND ANTIOXIDANT ACTIVITIES OF Tinospora crispa MIERS STEM EXTRACT." Scientific Journal of Tra Vinh University 1, no. 40 (2020): 58–69. http://dx.doi.org/10.35382/18594816.1.40.2020.617.

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The study was conducted to analyze some of the bioactive compounds and the antioxidant capacity of Tinospora crispa stem extract. Tinospora crispa stem extract is a prerequisite for the production of products capable of supporting and treating diseases. Tinospora crispa stem extract is made by immersion method withsolvents (water, ethanol 80o and methanol) and combined with ultrasound. Antioxidant activities were tested using DPPHmethods and phenolic, flavonoid, polysaccharide, tannin content were determined by the spectrophotometer method. The results showed that the moisture content was 61.09% and high extraction efficiency of Tinospora crispa stem were between 3.69% and 6.95% respectively. The extract of Tinospora crispa stem contains the presence of biological compounds such as alkaloids, flavonoids, saponin, steroids, tannins and phenols. The phenolic, flavonoid, polysaccharide and tannin content of Tinospora crispa stem were318.91 mg gallic acid/g dry; 36.71 mg quercetin/g dry; 10.38 mg GE/g dry and 38.42 mg tannic acid/g dry respectively. Tinospora crispa stem has antioxidant ability by DPPH method with IC50 value of water, ethanol 80o and methanol 113.69 mg/mg; 89.12 mg/mg; 62.19 mg/mg, respectively. Thus, the Tinospora crispastem extract had bioactive compounds and antioxidant activities, is a potential source of raw materials for research and applications.
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Farris, Emmanuele, Martino Orrù, Mariano Ucchesu, Arianna Amadori, Marco Porceddu, and Gianluigi Bacchetta. "Morpho-Colorimetric Characterization of the Sardinian Endemic Taxa of the Genus Anchusa L. by Seed Image Analysis." Plants 9, no. 10 (2020): 1321. http://dx.doi.org/10.3390/plants9101321.

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In this work, the seed morpho-colorimetric differentiation of the Sardinian endemic species of Anchusa (Boraginaceae) was evaluated. In Sardinia, the Anchusa genus includes the following seven taxa: A. capellii, A. crispa ssp. crispa, A. crispa ssp. maritima, A. formosa, A. littorea, A. montelinasana, and A. sardoa. Seed images were acquired using a flatbed scanner and analyzed using the free software package ImageJ. A total of 74 seed morpho-colorimetric features of 2692 seed lots of seven taxa of Anchusa belonging to 17 populations were extrapolated and used to build a database of seed size, shape, and color features. The data were statistically elaborated by the stepwise linear discriminant analysis (LDA) to compare and discriminate each accession and taxon. In addition, the seed morpho-colorimetric differences among coastal and mountainous taxa were evaluated. Considering the ecological conditions, the LDA was able to discriminate among the Anchusa taxa with a correct identification of 87.4% and 90.8% of specimens for mountainous and coastal plants, respectively. Moreover, the LDA of the 17 populations of Anchusa showed a low separation among species and populations within the coastal group, highlighting how the long-distance dispersal by flotation on the sea water surface and the pollination network may influence the similarity patterns observed. In addition, a misattribution was observed for A. crispa ssp. crispa, which was misclassified as A. crispa ssp. maritima in 14.1% of cases, while A. crispa ssp. maritima was misidentified as A. crispa ssp. crispa in 21.1% of cases, highlighting a close phenotypic relationship between these two taxa. The statistical results obtained through the seed image analysis showed that the morpho-colorimetric features of the seeds provide important information about the adaptation and evolution of Anchusa taxa in Sardinia.
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6

Albrahim, Tarfa, Moonerah M. Alnasser, Mashael R. Al-Anazi, Muneera D. ALKahtani, Saad Alkahtani, and Ahmed A. Al-Qahtani. "In Vitro Studies on the Immunomodulatory Effects of Pulicaria crispa Extract on Human THP-1 Monocytes." Oxidative Medicine and Cellular Longevity 2020 (September 26, 2020): 1–14. http://dx.doi.org/10.1155/2020/7574606.

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Background. Pulicaria crispa (P. crispa) is a plant from the Compositae family that exhibits antioxidant, anti-inflammatory, antibacterial, and cytotoxic activities. Objective. The current study aimed at investigating the immunomodulatory effects of P. crispa extract in lipopolysaccharide- (LPS-) stimulated human monocytic THP-1 cells. Methods. To induce macrophage differentiation, THP-1 cell lines were treated with phorbol-12-myristate 13-acetate, followed by exposure to LPS with or without 50 or 100 μg/ml of P. crispa extract. The following tests were employed to test the immunomodulatory effects of the extract: MTT assay, ELISA, Western blotting analysis, cell migration and phagocytosis assays, and Annexin V staining method. Results. Exposure to 100 μg/ml P. crispa extract significantly reduced THP-1 cell proliferation, migration, and phagocytosis (in LPS-stimulated cells, but not in unstimulated cells). Moreover, the extract alone significantly reduced the rate of THP-1 cell apoptosis, while it increased the rate of late apoptosis. Molecular investigations showed that treatment with P. crispa extract significantly upregulated the expression of ERK1, p-MAPK, P-P38, and Bcl2, while it significantly reduced the expression of ERK5, Bax, NF-κB, P-NF-κB, CCL1, CCL2, CCL5, CCL22, CXCL1, and CXCL10. Conclusion. Pulicaria crispa extract exhibited anti-inflammatory, antiproliferative, antimigratory, and antiphagocytic effects in LPS-stimulated THP-1 cells. Future studies should investigate these mechanisms in animal models with chronic inflammatory diseases.
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7

Pretorius, J. C., S. Magama, and P. C. Zietsman. "Purification and identification of antibacterial compounds from Euclea crispa subsp. crispa (Ebenaceae) leaves." South African Journal of Botany 69, no. 4 (2003): 579–86. http://dx.doi.org/10.1016/s0254-6299(15)30298-2.

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8

Magama, S., J. C. Pretorius, P. C. Zietsman, and B. E. van Wyk. "Antimicrobial properties of extracts from Euclea crispa subsp. crispa (Ebenaceae) towards human pathogens." South African Journal of Botany 69, no. 2 (2003): 193–98. http://dx.doi.org/10.1016/s0254-6299(15)30345-8.

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9

Sainsbury, Frank, Alexander D. Tattersall, Michael J. Ambrose, Lynda Turner, T. H. Noel Ellis, and Julie M. I. Hofer. "A crispa null mutant facilitates identification of a crispa-like pseudogene in pea." Functional Plant Biology 33, no. 8 (2006): 757. http://dx.doi.org/10.1071/fp06090.

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The genomes of several legume species contain two Phantastica-like genes. Previous studies on leaf development have found that Phantastica confers leaf blade adaxial identity in plant species with simple leaves and leaflet adaxial identity in pea (Pisum sativum L.), a legume with compound leaves. Previous characterisation of the phantastica mutant of pea, crispa, showed it had radialised leaflets, but stipules were not radialised. This suggested either that mutation of a second redundant gene was required for radialisation of stipules, or, that a null mutation was required. Previously characterised crispa mutants may not have exhibited radialised stipules because they were weak alleles. In this work we show that pea has a second Phantastica-like gene, which lies on a different chromosome to Crispa. The second gene was found to be a pseudogene in several genotypes of pea, therefore it would not have a role in conferring stipule adaxial identity. A new deletion mutant, crispa-4 was identified. The mutant has radialised stipules and leaflets, showing that Crispa confers adaxial identity on both these organs in pea. The nucleotide sequence data reported here are in the EMBL and GenBank Nucleotide Databases under the accession numbers DQ486060 (JI 2822), DQ486061 (JI 15), DQ486062 (JI 281) and DQ486063 (JI 399).
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10

Zhang, Xin, Gao Chen, Weichang Gong, and Weibang Sun. "Buddleja caryopteridifolia (Scrophulariaceae), a species to be recognized based on morphology, floral scent and AFLP data." Phytotaxa 161, no. 3 (2014): 181. http://dx.doi.org/10.11646/phytotaxa.161.3.1.

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Buddleja caryopteridifolia was treated as a synonym of B. crispa in Flora of China. However, it was found that the two entities had different phenologies as well as morphology in the sympatric habitat investigated. Buddleja crispa flowers from mid-March to mid-May while B. caryopteridifolia blooms from early June to mid-September. In this study, the comprehensive comparative analyses of morphological traits, floral scent composition and amplified fragment length polymorphism (AFLP) data were utilized to determine whether B. caryopteridifolia should be recognized as a separate species. Among 13 morphological characters, all but calyx length were significantly different (all p<0.05, t-test) between the two species. Both cluster analysis and principal coordinates analysis (PCoA) of AFLP markers produced two distinct clusters for B. crispa and B. caryopteridifolia. The results of floral scent indicated several differences between B. crispa and B. caryopteridifolia. The main volatile compound of B. crispa was Benzaldehyde, while that of B. caryopteridifolia mostly consisted of trans-β-Ocimene. Therefore, all analyses supported the rehabilitation of B. caryopteridifolia as an independent species.
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11

Rossbach, Felix I., Edoardo Casoli, Milan Beck, and Christian Wild. "Mediterranean Red Macro Algae Mats as Habitat for High Abundances of Serpulid Polychaetes." Diversity 13, no. 6 (2021): 265. http://dx.doi.org/10.3390/d13060265.

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The Mediterranean Sea harbors more than 17,000 eukaryotic marine species, with several ecosystems recognized as biodiversity hotspots, such as Posidonia oceanica meadows. Recent research indicates that benthic mats formed by the fleshy red alga Phyllophora crispa are also associated with high species richness. Among key groups found in these mats are sessile polychaetes, which live as epiphytes on the red algae thalli. Knowledge of abundance, species richness, and spatial variation of polychaetes associated with these habitats is still scarce. We carried out a comparative assessment focusing on serpulid polychaetes within samples from P. crispa mats and neighboring P. oceanica meadows at six different sampling sites around Giglio Island (Tyrrhenian Sea, Italy). A total of 17 serpulid taxa were identified. The abundance of serpulids (5665 individuals m−2 of P. crispa mat) were similar to neighboring P. oceanica meadows (2304 individuals m−2 leaves and 5890 individuals m−2 shoots). The number of serpulid taxa was significantly higher in P. crispa mats (average 6.63 ± 1.32 taxa) compared to P. oceanica beds (average 1.56 ± 0.63 and 1.84 ± 1.04 taxa in leaves and shoots, respectively). Within habitat type, there were no significant differences in species richness between sites. The most abundant species found was Josephella marenzelleri (61% of individuals), while Vermiliopsis spp. and Bathyvermilia sp. were exclusively found in P. crispa samples. Our results highlight that P. crispa mats host an exceptional diversity and that these habitats should be included in conservation strategies. Further research should focus on the significance of other important taxonomic groups within these mats and evaluate the distribution of P. crispa in different regions of the Mediterranean Sea.
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12

Sánchez Gullón, Enrique, and Pedro Weickert. "A new specie of Iridaceae for SW of Spain." Acta Botanica Malacitana 29 (December 1, 2004): 297–98. http://dx.doi.org/10.24310/abm.v29i0.7248.

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Una nueva especie de Iridaceae para el sudoeste de España.Palabras clave. Flora, corología, Ferraria crispa, Iridaceae, xenófito adventicio naturalizado, Huelva, AndalucíaKey words. Flora, corology, Ferraria crispa, Iridaceae, xenophyte adventitious naturalised, Huelva, Andalusia
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13

Dendougui, Hocine, Samir Benayache, Fadila Benayache, and Joseph D. Connoly. "Sesquiterpene lactones from Pulicaria crispa." Fitoterapia 71, no. 4 (2000): 373–78. http://dx.doi.org/10.1016/s0367-326x(00)00133-7.

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14

Lam, Sio-Hong, Chi-Tun Ruan, Po-Hung Hsieh, Ming-Jai Su, and Shoei-Sheng Lee. "Hypoglycemic Diterpenoids from Tinospora crispa." Journal of Natural Products 75, no. 2 (2012): 153–59. http://dx.doi.org/10.1021/np200692v.

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15

Choudhary, M. Iqbal, Muhammad Ismail, Zulfiqar Ali, Khozirah Shaari, Nordin H. Lajis, and Atta-ur-Rahman. "Alkaloidal Constituents of Tinospora Crispa." Natural Product Communications 5, no. 11 (2010): 1934578X1000501. http://dx.doi.org/10.1177/1934578x1000501109.

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Phytochemical investigations of the stems of Tinospora crispa led to the isolation of one new aporphine alkaloid, N-formylasimilobine 2- O-β-D-glucopyranoside (1), along with six known alkaloids, N-formylasimilobine 2- O-β-D-glucopyranosyl-(1→2)-β-D-glucopyranoside (2) (tinoscorside A), N-formylanonaine (3), N-formyldehydroanonaine (4), N-formylnornuciferine (5), N-demethyl -N-formyldehydronornuciferine (6), magnoflorine (7), paprazine (8), N-trans-feruloyltyramine (9), and cytidine (10). The structure of new compound 1 was deduced on the basis of spectroscopic data.
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16

Синцова, О. В., М. М. Монастырная, Е. А. Пислягин та ін. "Противовоспалительная активность полипептида актинииHeteractis crispa". Биоорганическая химия 41, № 6 (2015): 657–63. http://dx.doi.org/10.7868/s0132342315060147.

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17

Ismail, Muhammad, and Muhammad Iqbal Choudhary. "Compounds Isolated from Tinospora crispa." Chemistry of Natural Compounds 52, no. 6 (2016): 1151–53. http://dx.doi.org/10.1007/s10600-016-1892-0.

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18

Martani, Natalia Sri, and Fatmaria Fatmaria. "Pemanfaatan Penawar Sampai (Tinospora crispa L.) sebagai Tanaman Obat Tradisional oleh Suku Dayak Ngaju." Jurnal Pharmascience 7, no. 2 (2020): 156. http://dx.doi.org/10.20527/jps.v7i2.8799.

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Kehidupan sub rumpun Suku Dayak Ngaju di Kalimantan Tengah sangat bergantung pada hutan dan alam. Masyarakatnya menggunakan berbagai obat-obatan tradisional yang bermanfaat, salah satunya adalah tanaman penawar sampai (Tinospora crispa L.). Penelitian ini bertujuan mengeksplorasi tanaman T. crispa sebagai obat tradisional Suku Dayak Ngaju. Metode yang digunakan ialah penelitian eksploratif dari Basir, para ahli pengobatan tradisional Suku Dayak Ngaju. Pemilihan Basir menggunakan metode snowball sampling. Hasil penelitian ini menunjukkan bahwa T. crispa yang digunakan oleh masyarakat Suku Dayak Ngaju secara empiris digunakan sebagai antihipertensi; menunjang diabetes agar terkontrol; pengobatan penyakit kulit; melawan alergi; meningkatkan selera makan; penyembuhan luka; sakit kuning (hepatitis); penyembuhan rematik; antimalaria; menstimulasi saraf; dan antidiare. Kesimpulan penelitian ini bahwa T. crispa merupakan tanaman obat tradisional yang memiliki banyak manfaat. The life of the sub ethnic of Dayak Ngaju Tribe in Central Kalimantan is very dependent on the forest and nature. People use a variety of traditional medicines are beneficial, one of which is the penawar sampai (Tinospora crispa L.). The research objective to explore the utilization of the T. crispa as a medicinal plant traditional Dayak Ngaju Tribe. The method used is exploratory research of Basir, the traditional healers from Dayak Ngaju Tribe. The selection of Basir using the method of snowball sampling. The results of this study indicate that the antidote to that used by the people of Dayak Ngaju Tribe empirically used as an antihypertensive; support to controlled diabetes; a skin disease that can be treated; fight allergies; improves appetite; wound healing; yellow fever (hepatitis); the healing of rheumatism; antimalaria; stimulates the nerves and anti diarrhea. The conclusion of this study that the antidote to is a traditional medicinal plant that has many benefits.Keywords: Penawar Sampai, Tinospora crispa L., Medicinal Plants, Dayak Ngaju Tribe
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19

Koppers, A. J., G. M. Gibbs, T. Reddy, P. McIntyre, and M. K. O'Bryan. "182. ROLE OF CRISP4 IN ION CHANNEL REGULATION AND MALE REPRODUCTION." Reproduction, Fertility and Development 22, no. 9 (2010): 100. http://dx.doi.org/10.1071/srb10abs182.

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CRISPs are a group of 3 proteins found in mammals (4 in the mouse) which show a strong expression bias in the male reproductive organs. Whilst the function of most CRISPs are yet to be elucidated, mouse CRISP2 is a known regulator of the ion channel, ryanodine receptor. CRISP4 is most abundantly produced by the principal cells of the epididymis and are secreted into the lumen, where they adhere to sperm during epididymal transit. In this study we examined the role of CRISP4 ion channel regulation in mouse spermatozoa through cell assays and mouse models. The identification of the Transient Receptor Potential (TRP) ion channel, TRPM8 to interact with CRISP4 was confirmed using stably-transfected CHO cell lines. Production of CRISP4 KO mouse model, whilst males are fertile, they exhibit a subtle infertility phenotype characterized by a reduced ability to capacitate and undergo the acrosome reaction. This data is further emphasized by the ability of TRPM8 agonists, icillin and menthol, to inhibit the acrosome reaction in mouse spermatozoa that could be prevented by the addition of recombinant CRISP4 crisp domain. Corresponding to these data, CRISP4 is localized to the tail and head of mouse spermatozoa. In conclusion, we have demonstrated that CRISP4 is a regulator of TRPM8 in mouse spermatozoa, and due to its expression and localization pattern is an important protein in sperm epididymal maturation.
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20

Wahyuningrum, Retno, Ritmaleni Ritmaleni, Tatang Irianti, Subagus Wahyuono, and Takushi Kaneko. "ANTITUBERCULOSIS ACTIVITY OF EXTRACT AND FRACTIONS OF TINOSPORA CRISPA AGAINST MYCOBACTERIUM TUBERCULOSIS H37RV USING MYCOBACTERIA GROWTH INDICATOR TUBE AND AGAR PROPORTION METHOD." Asian Journal of Pharmaceutical and Clinical Research 11, no. 3 (2018): 132. http://dx.doi.org/10.22159/ajpcr.2018.v11i3.22587.

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Objective: The increasing incidence of multidrug-resistant tuberculosis (TB) has created a need to discover a new anti-TB drug candidates. The aim of this study was to screen extract and fractions of Tinospora crispa for activity against Mycobacterium tuberculosis H37Rv.Methods: The dried and pulverized T. crispa stem was extracted by maceration method using ethanol (96%). The anti-TB activity was carried out using mycobacteria growth indicator tube (MGIT) system and agar proportion method with Lowenstein–Jensen (LJ) medium.Result: The result of this study showed that ethanolic extract and fractions of T. Crispa did not exhibit anti-TB activity in the range of 100–1000 μg/ml with MGIT method, while with agar proportion method, there were M. tuberculosis colonies growth on the LJ containing 1000 μg/ml extract slants.Conclusion: The tested extract and fractions of T. crispa have no anti-TB activity against M. tuberculosis until 1000 μg/ml.
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21

Brunner, Ivano, Franziska Brunner, and Gary A. Laursen. "Characterization and comparison of macrofungal communities in an Alnus tenuifolia and an Alnus crispa forest in Alaska." Canadian Journal of Botany 70, no. 6 (1992): 1247–58. http://dx.doi.org/10.1139/b92-158.

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Occurrence of macrofungal sporocarps, vascular plants, mosses, and lichens was recorded during the growing season of 1987 in an Alnus tenuifolia and an Alnus crispa forest near Fairbanks, Alaska. In total, 131 macrofungal species were observed, with 57 species recorded for the A. tenuifolia forest, 95 species for the A. crispa forest, and 21 species common to both. The ratio of macrofungal species to species of plants and lichens at the A. tenuifolia site was 2.0, but it was 3.3 at the A. crispa site. Similarity of macrofungi and plant–lichens ranged between 62 and 82% among plots within the same study sites and between 17 to 30% among plots between various study sites. Species–area curves for both study sites indicate that an area of 3000 m2 should contain the representative macrofungal community. The predominant and characteristic macrofungi within the A. tenuifolia forest were the ectomycorrhizal species Hebeloma cf. crustuliniforme and Alpova diplophloeus and the saprobic species Clitocybe cf. catervata. Within the A. crispa forest, the predominant and characteristic ectomycorrhizal species were Russula alnicrispae and Russula subarctica and the saprobic species Plicatura nivea and Clitocybe subalutacea. Common and frequent species in both forest types were Naucoria escharoides s.l., Polyporus varius, Lycoperdon perlatum, Coprinus domesticus, and Mycena speirea. Key words: Alaska, Alnus tenuifolia forest, Alnus crispa forest, macrofungal communities, mycoecology.
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Wahyuningrum, Retno, Ritmaleni Ritmaleni, Tatang Irianti, Subagus Wahyuono, Takushi Kaneko, and Titik Nuryastuti. "Antituberculosis Activity of Brotowali (Tinospora crispa) Extract and Fractions against Mycobacterium tuberculosis using Microplate Alamar Blue Assay Method." Majalah Obat Tradisional 22, no. 2 (2017): 124. http://dx.doi.org/10.22146/tradmedj.27925.

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Tuberculosis (TB), in which caused by pathogenic bacteria, Mycobacterium tuberculosis, has become the major causes of death among all of infectious diseases. The increasing incidence of multidrug-resistant tuberculosis (MDR-TB) and extensively drug-resistant tuberculosis (XDR-TB) has created a need to discover a new antituberculosis drug candidate. The aim of this study was to screen extract and fractions of Tinospora crispa for activity against Mycobacterium tuberculosis H37Rv using the Microplate Alamar Blue Assay (MABA) method. T. crispa extract was prepared by maceration in ethanol (96%) and antituberculosis activity was carried out using MABA method. The result of this study showed that ethanolic extract of T. crispa exhibit antituberculosis activity with minimum inhibition concentration of 12.5 mg/ml.
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23

HUGHEY, JEFFERY R., and KATHY ANN MILLER. "Genetic investigation of three type specimens of Osmundea (Rhodomelaceae, Rhodophyta) from the Gulf of California, Mexico and California, USA." Phytotaxa 489, no. 1 (2021): 65–78. http://dx.doi.org/10.11646/phytotaxa.489.1.5.

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The taxonomic status of species assigned to the marine red algal genus Osmundea from Pacific North America has not been critically studied. We analyzed the complete organellar genomes of an isotype specimen of O. sinicola and conducted a genetic comparison of rbcL and COI-5P markers based on 15 specimens of Laurencia scrippsensis, O. crispa, and O. sinicola collected from California, the Gulf of California, and Pacific Baja California, including their type specimens. The mitogenome of O. sinicola was 25,021 bp in length and contained 44 genes, and the plastid genome was 171,419 bp with 225 genes. Both genomes show a high level of gene synteny with previously published organellar chromosomes from the Rhodomelaceae. Phylogenetic analysis of the rbcL and COI-5P genes identified two distinct clades, one containing the isotype of O. sinicola, and the other included the isotype of O. crispa and holotype of Laurencia scrippsensis. These data show that L. scrippsensis is a heterotypic synonym of O. crispa, rather than of O. sinicola. They support the recognition of two species, O. crispa from Monterey, California to Baja California Sur, and O. sinicola from Baja California Sur to the Gulf of California. California specimens identified as O. sinicola are misidentified O. crispa. Reports of O. sinicola from outside this range based on morpho-anatomy require confirmation by DNA sequencing. These genetic results highlight the need further analyses of type material from the Rhodomelaceae.
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Pangua, Emilia, Lorena Garcia-Alvarez, and Santiago Pajaron. "Studies on Cryptogramma crispa Spore Germination." American Fern Journal 89, no. 2 (1999): 159. http://dx.doi.org/10.2307/1547350.

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25

Choudhary, M. Iqbal, Muhammad Ismail, Khozirah Shaari, Ahmed Abbaskhan, Samina A. Sattar, and Nordin H. Lajis. "cis-Clerodane-Type Furanoditerpenoids fromTinospora crispa." Journal of Natural Products 73, no. 4 (2010): 541–47. http://dx.doi.org/10.1021/np900551u.

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26

Ahmad, Ijaz, Abdul Malik, Nighat Afza, et al. "Enzymes Inhibitory Constituents From Buddleja Crispa." Zeitschrift für Naturforschung B 60, no. 3 (2005): 341–46. http://dx.doi.org/10.1515/znb-2005-0319.

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Steroidal galactoside 1 and aryl esters 2 and 3 have been isolated from Buddleja crispa, along with ginipin 4, gardiol 5, 1-heptacosanol 6, and methyl benzoate 7, isolated for the first time from this species. The structures of all of the compounds were determined by spectroscopic techniques and chemical studies. The steroidal galactoside 1 is an inhibitor of lipoxygenase. Compounds 1- 3 displayed inhibitory activity against butyrylcholinesterse, while compounds 2 and 3 further showed inhibition against acetylcholinesterase
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27

Cavin, Alexandre, Kurt Hostettmann, Wahjo Dyatmyko, and Olivier Potterat. "Antioxidant and Lipophilic Constituents ofTinospora crispa." Planta Medica 64, no. 05 (1998): 393–96. http://dx.doi.org/10.1055/s-2006-957466.

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KODANI, Shinya, Kanako HAYASHI, Mamiko HASHIMOTO, Takashi KIMURA, Munehiko DOMBO, and Hirokazu KAWAGISHI. "New Sesquiterpenoid from the MushroomSparassis crispa." Bioscience, Biotechnology, and Biochemistry 73, no. 1 (2009): 228–29. http://dx.doi.org/10.1271/bbb.80595.

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29

Adam, S. E. I. "Toxic effects ofFrancoeuria crispa in rats." Phytotherapy Research 12, no. 7 (1998): 476–79. http://dx.doi.org/10.1002/(sici)1099-1573(199811)12:7<476::aid-ptr330>3.0.co;2-k.

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30

Henrici, Alick. "Plicatura crispa - spreading rapidly in Britain." Field Mycology 19, no. 2 (2018): 61–64. http://dx.doi.org/10.1016/j.fldmyc.2018.04.010.

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31

Sorgato, José Carlos, Jackeline Schultz Soares, Luan Marlon Ribeiro, and Anderson Giaretta Cabral. "Ornamental potential of Schomburkgia crispa Lindl." Ornamental Horticulture 27, no. 2 (2021): 155–61. http://dx.doi.org/10.1590/2447-536x.v27i2.2277.

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Abstract Orchids are one of the groups of plants with the greatest commercialization potential. They have floral characteristics highly valued in the sector of flowers and ornamental plants. However, exotics species are the most commercialized. The native species are still little explored for their ornamental potential. Thus, this work describes the vegetative and floral morphological characteristics of Schomburgkia crispa Lindl. aiming at evaluating its ornamental potential. For such, seven individuals were chosen. The quantitative characters were evaluated in all plants, totaling fifty pseudobulbs and eighty-eight flowers. During flowering, the most representative plant was chosen for the visual evaluation of its morphological features through photographs. A floral diagnosis sheet based on photos of fresh flowers was prepared by keeping the maximum level of morphological details. At the end of the experimental period, averages and standard deviations were calculated for each character evaluated. The species S. crispa presented, on average, plants 46.17 cm long, 31.50 cm wide, and with 88 cm of diameter. For flowering characters, the species presented in general 16.50 flowers per plant, 14.67 per flower stem, and 4.66 flowers opened per day, with an average durability of 32 days. Thus, we conclude that the species S. crispa has a great ornamental potential for use in ornamental horticulture.
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32

Bukvicki, Danka, M. Veljic, Marina Sokovic, Slavica Grujic, and P. D. Marin. "Antimicrobial activity of methanol extracts of Abietinella abietina, Neckera crispa, Platyhypnidium riparoides, Cratoneuron filicinum and Campylium protensum mosses." Archives of Biological Sciences 64, no. 3 (2012): 911–16. http://dx.doi.org/10.2298/abs1203911b.

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The antibacterial and antifungal activity of methanol extracts of the genuine mosses Abietinella abietina, Neckera crispa, Platyhypnidium riparoides, Cratoneuron filicinum var. filicinum and Campylium protensum were evaluated. Antibacterial activity was tested against Gram (+) Staphylococcus aureus, Micrococcus flavus, Bacillus cereus and Gram (-) bacteria Escherichia coli and Salmonella typhimurium. Antifungal activity was tested using micromycetes Trichoderma viride, Penicillium funiculosum, Penicillium ochrochloron, Aspergillus flavus, A. niger and A. fumigatus. The methanol extracts of all moss species showed an antimicrobial effect against the tested microorganisms. Significant antibacterial effect was achieved for Cratoneuron filicinum and Neckera crispa. The most sensitive bacteria were Bacillus subtilis and Micrococcus flavus. Abietinella abietina and Neckera crispa showed an antifungal effect against micromycetes Trichoderma viride, Penicillium ochrachloron, P. funiculosum and Aspergillus flavus.
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33

Holken Lorensi, Graziela, Raquel Soares Oliveira, Allan P. Leal, et al. "Entomotoxic Activity of Prasiola crispa (Antarctic Algae) in Nauphoeta cinerea Cockroaches: Identification of Main Steroidal Compounds." Marine Drugs 17, no. 10 (2019): 573. http://dx.doi.org/10.3390/md17100573.

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Prasiola crispa is a macroscopic green algae found in abundance in Antarctica ice free areas. Prasiola crispan-hexaneextract (HPC) induced insecticidal activity in Nauphoeta cinerea cockroaches after 24 h of exposure. The chemical analysis of HPC revealed the presence of the followingphytosterols: β-sitosterol, campesterol and stigmasterol. The incubation of cockroach semi-isolated heart preparations with HPC caused a significant negative chronotropic activity in the heartbeats. HPC affected the insect neuromuscular function by inducing a complete inhibition of the cockroach leg-muscle twitch tension. When the isolated phytosterols were injected at in vivo cockroach neuromuscular preparations, there was a progressive inhibition of muscle twitches on the following order of potency: β-sitosterol &gt; campesterol &gt; stigmasterol. HPC also provoked significant behavioral alterations, characterized by the increase or decrease of cockroach grooming activity, depending on the dose assayed. Altogether, the results presented here corroborate the insecticide potential of Prasiola crispa Antarctic algae. They also revealed the presence of phytosterols and the involvement of these steroidal compounds in the entomotoxic activity of the algae, potentially by modulating octopaminergic-cholinergic pathways. Further phytochemical-combined bioguided analysis of the HPC will unveil novel bioactive compounds that might be an accessory to the insecticide activity of the algae.
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Garbary, David J., and Nicholas M. Hill. "Natural history of the terrestrial green alga, Prasiola crispa (Trebouxiophyceae), and associated Herring Gulls on Brier Island, Nova Scotia." Proceedings of the Nova Scotian Institute of Science (NSIS) 49, no. 1 (2017): 49. http://dx.doi.org/10.15273/pnsis.v49i1.6979.

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The local distribution of Prasiola crispa is reported for the first time in Nova Scotia. It was common on emergent basalt outcrops in a coastal wetland on the Bay of Fundy shores of Brier Island. The alga was present on 19 of 102 basalt outcrops in one of the breeding colonies of the Herring Gull, Larus argentatus, and was only associated with basalt outcrops with gull feces. Patches of P. crispa were typically associated with the north facing slopes of the rock or were present in depressions or parts of the rock shaded by adjacent vegetation. At Western Light, the gulls are both facilitating the presence of P. crispa and acting as ecosystem engineers by nesting in the adjoining vegetation where their trampling and nutrient inputs are modifying the surrounding wetland ecosystem.
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35

ZHAO, QI, TOLGOR B, YONGCHANG ZHAO, ZHULIANG YANG, and KEVIN D. HYDE. "Species diversity within the Helvella crispa group (Ascomycota: Helvellaceae) in China." Phytotaxa 239, no. 2 (2015): 130. http://dx.doi.org/10.11646/phytotaxa.239.2.2.

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The white saddle-mushroom, a well-known European species, has long been named as Helvella crispa in China. In this study, phylogenetic analyses of combined ITS, nrLSU, tef1-α, rpb2 and mcm7 sequence data, showed that the Chinese H. crispa-like samples represent a species complex, which contains at least six phylogenetic species. Three of these species, H. involuta, H. orienticrispa and H. pseudoreflexa, are introduced as new species in this paper. The remaining two taxa are not described due to paucity of material. Among the six phylogenetic species, H. zhongtiaoensis is more closely related to European H. crispa than the remaining Chinese species. They are provided with descriptions, photographs and are compared with similar species. A key to the Chinese morphologically recognizable taxa of this complex is provided.
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36

Viira, Viive, and Richard J. Aldridge. "Upper Wenlock to Lower Přídolí (Silurian) conodont biostratigraphy of Saaremaa, Estonia, and a correlation with Britain." Journal of Micropalaeontology 17, no. 1 (1998): 33–50. http://dx.doi.org/10.1144/jm.17.1.33.

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Abstract. The closely related conodonts Ozarkodina bohemica, O. snajdri and O. crispa form a clade that provides useful biostratigraphical indices through the upper Silurian. Collections from boreholes and surface outcrops on Saaremaa and from a borehole at Kolka, Latvia, contain new morphotypes of O. bohemica and O. crispa. A new subspecies, O. snajdri parasnajdri, is also distinguished, occurring above O. crispa in the Kuressaare and lowermost Kaugatuma stages. Evidence from conodonts and other fossils, primarily chitinozoans, ostracods and ichthyoliths, can be used to correlate the upper Silurian succession of Saaremaa with those of the Welsh Borderland and Gotland, although some problems remain to be solved. The microfossil distribution suggests that there may be a major break at the base of the Ludlow Bone Bed Member at Ludlow, equivalent to the Kuressaare Formation on Saaremaa.
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37

Perold, S. M. "METZGERIALES-FOSSOMBRONIACEAE." Bothalia 27, no. 2 (1997): 137–39. http://dx.doi.org/10.4102/abc.v27i2.671.

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38

Zahirnia, Amirhossein, Mitra Boroomand, Hassan Nasirian, Aref Salehzadeh, and Sara Soleimani-Asl. "Comparing cytotoxicity of propoxur and Nepeta crispa (Lamiales: Lamiaceae) essential oil against invertebrate (Sf9) and vertebrate (L929) cell lines." November-2019 12, no. 11 (2019): 1698–706. http://dx.doi.org/10.14202/vetworld.2019.1698-1706.

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Background and Aim: Attempts to use the plant products are to be an appropriate option due to substantial concerns about human health and environmental problems of using synthetic pesticides. Therefore, the cytotoxicity of Nepeta crispa essential oil was compared with propoxur against invertebrate (Sf9) and vertebrate (L929) cell lines. Materials and Methods: The cell lines of Sf9 and L929 which were derived from the ovary glands of fall armyworm, Spodoptera frugiperda (Lepidoptera: Noctuidae) and mouse fibroblast cells, respectively, were obtained from the National Cell Bank of Pasteur Institute of Iran. About a number of 2 × 103 cells were placed into the wells of 96-well plate experiments. Then, appropriate concentrations of essential oil of N. crispa plant and propoxur added to the wells. The cells were allowed to grow for 3-5 days and estimated the numbers of cells. The cells of control experiment wells contained only cells with dimethyl sulfoxide. All control and treatment experiments repeated at least four replicates. Results: Propoxur had negative effects on the viability of both invertebrate (Sf9) and vertebrate (L929) cell lines. The cytotoxicity of propoxur against invertebrate (Sf9) and vertebrate (L929) cell lines was gradually increased in accordance with propoxur concentrations. The cytotoxicity of N. crispa essential oil against vertebrate (L929) cell line was gradually decreased in accordance with plant concentrations, while the cytotoxicity of N. crispa essential oil against invertebrate (Sf9) cell line was strongly increased in accordance with plant concentrations. Conclusion: Plant essential oil not only had no negative effects but also had boosting effects on vertebrate cell viability. Essential oil of N. crispa plant had negative effects on invertebrate cell viability with the differences that the products derived from plants possessing of biodegradable and environmentally friendly derivatives, hydrolyzing rapidly in nature, and nearly having no destructive effects on environment, humans, or the mammals.
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Wang, Zhixin, Jingyu Liu, Xiangjian Zhong, et al. "Rapid Characterization of Chemical Components in Edible Mushroom Sparassis crispa by UPLC-Orbitrap MS Analysis and Potential Inhibitory Effects on Allergic Rhinitis." Molecules 24, no. 16 (2019): 3014. http://dx.doi.org/10.3390/molecules24163014.

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Sparassis crispa is a kind of edible fungus widely grows in the north temperate zone, which shows various medicinal properties. Due to the complexity of chemical constitutes of this species, few investigations have acquired a comprehensive configuration for the chemical profile of it. In this study, a strategy based on ultra-high performance liquid chromatography (UPLC) combined with Orbitrap mass spectrometer (MS) was established for rapidly characterizing various chemical components in S. crispa. Through the summarized MS/MS fragmentation patterns of reference compounds and systematic identification strategy, a total of 110 components attributed to six categories were identified for the first time. Moreover, allergic rhinitis (AR) is a worldwide inflammatory disease seriously affecting human health, and the development of drugs to treat AR has been a topic of interest. It has been reported that the extracts of S. crispa showed obvious inhibitory effects on degranulation of mast cell- and allergen-induced IgE and proinflammatory mediators, but the active components and specific mechanism were still not clear. Src family kinases (SFKs) participate in the initial stage of allergy occurrence, which are considered the targets of AR treatment. Herein, on the basis of that self-built chemical database, virtual screening was applied to predict the potential SFKs inhibitors in S. crispa, using known crystal structures of Hck, Lyn, Fyn, and Syk as receptors, followed by the anti-inflammatory activity evaluation for screened hits by intracellular calcium mobilization assay. As results, sparoside A was directly confirmed to have strong anti-inflammatory activity with an IC50 value of 5.06 ± 0.60 μM. This study provides a useful elucidation for the chemical composition of S. crispa, and demonstrated its potential inhibitory effects on AR, which could promote the research and development of effective agents from natural resources.
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Barnawi, Ibrahim Omar, and Imran Ali. "Anticancer Potential of Pulicaria crispa Extract on Human Breast Cancer MDA-MB-231 Cells." Letters in Drug Design & Discovery 16, no. 12 (2019): 1354–59. http://dx.doi.org/10.2174/1570180816666190712110224.

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Background: Breast cancer is the common cause of deaths among women globally with 15% mortality globally. Introduction: Today, about 80% of the rural population depends on natural products as primary health care. Pulicaria crispa (L., family Compositae) is utilized in traditional medicine for curing colds, coughs, colic, and excessive sweating and as a carminative. Methods: The extracts of Pulicaria crispa; grown in Saudi Arabia; were assessed to measure the cytotoxicity with MDA-MB-231 breast cancer cell lines. Soxhlet extraction was utilized for stem, leaves and flower with 70% ethanol. The cytotoxicity of the extracts with MDA-MB-231 breast cancer cells was evaluated by 3-(4, 5-dimethylthiazol-2-yl)-2, 5-diphenyltetrazolium bromide (MTT) and lactate dehydrogenase (LDH) assays. Results: The apoptotic cellular morphological alterations were detected by fluorescence microscopes. The results indicated that Pulicaria crispa exhibited a strong anticancer activity with a halfmaximal inhibitory concentration (IC50) of 180 µg/mL against breast cancer cells. The loss in cell integrity, shrinkage of cytoplasm, and cell detachment were seen in the extract treated with MDAMB- 231 cells. The cell death was due to membrane destruction. Conclusion: Pulicaria crispa extracts indicated significant cytotoxicity against human breast cancer cells (MDA-MB-231 cells). The extract of this plant may be given to the patients having breast cancer.
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41

MARTÍNEZ-AZORÍN, MARIO, MANUEL B. CRESPO, and ANTHONY P. DOLD. "New data on Albuca crispa (Hyacinthaceae, Ornithogaloideae), an erect-flowered Albuca from South Africa." Phytotaxa 104, no. 1 (2013): 1. http://dx.doi.org/10.11646/phytotaxa.104.1.1.

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Within the framework of a taxonomic revision of the genus Albuca we here present new data on Albuca crispa, a species described as having undulate-crispulate leaves and white-green nodding flowers, it being included in A. subgen. Falconera section Trianthera (as series Trianthera). After studying both herbarium specimens and living plants from the type locality and other locations, it is clear that the protologue of A. crispa includes remarkable inaccuracies that make the understanding of that species very difficult, and that therefore are in need of correction. Furthermore, the new data would support the transfer of Albuca crispa to A. subgen. Mitrotepalum, a group characterized by the erect flowers and strongly hooded inner tepals. A complete description is presented for this species, and data on morphology, ecology, and distribution are reported. Affinities and divergences with other close allies are also discussed, and evidence is shown to propose amendment of author citation.
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42

Bakhari, Nor Aziyah, Siti Nur Amirah Diana Fadzillah, and Norain Isa. "Chemical Constituents of the Insecticidal Active Extract of Tinospora crispa." Scientific Research Journal 10, no. 1 (2019): 23. http://dx.doi.org/10.24191/srj.v10i1.5408.

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Tinospora crispa Miers (Menispermaceae) is a climbing vine with stems rich in warts. The plant is called Akar Seruntum or Patawali in Malaysia and is widely used for treating skin complaints, malaria, bacterial abscess, high blood pressure and diabetes. In the present study, the stems of T. crispa were collected from the locality and succesively extracted with petroleum ether, followed by chloroform and ethanol. The insecticidal active extract (ethanol extract) was subjected to column chromatography of silica gel eluted with a gradient mobile phase containing hexane, chloroform and ethanol. Among the chemical constituents isolated are n-tetracosyl trans-ferulate and n-octacosyl alcohol, along with three known aporphine alkaloids; N-formylnornuciferine, N-acetylnornuciferine and lysicamine. All compounds were identified by comparing their spectroscopic data (UV, IR, 1H NMR, MS) with data from corresponding values in the literature. Isolation of n-tetracosyl trans-ferulate and n-octacosyl alcohol is reported the first time for T. crispa.
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Kim, Eun-Jung, Kwan-Hee Yoo, Yang-Sup Kim, Soon-Ja Seok, and Jun-Ho Kim. "Biological Activities of Wild Sparassis crispa Extracts." Korean Journal of Mycology 43, no. 1 (2015): 40–46. http://dx.doi.org/10.4489/kjm.2015.43.1.40.

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44

Lima, Igara Oliveira, Vivian Bruna Machado Costa, Wemerson Neves Matias, et al. "Biological activity of Herissantia crispa (L.) Brizicky." Revista Brasileira de Farmacognosia 19, no. 1b (2009): 249–54. http://dx.doi.org/10.1590/s0102-695x2009000200012.

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45

Stavri, Michael, K. T. Mathew, Andrew Gordon, Steven D. Shnyder, Robert A. Falconer, and Simon Gibbons. "Guaianolide sesquiterpenes from Pulicaria crispa (Forssk.) Oliv." Phytochemistry 69, no. 9 (2008): 1915–18. http://dx.doi.org/10.1016/j.phytochem.2008.03.012.

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46

Jiang, Meng-Yuan, Ling Zhang, Ze-Jun Dong, and Ji-Kai Liu. "Two New Metabolites from Basidiomycete Sparassis crispa." Zeitschrift für Naturforschung B 64, no. 9 (2009): 1087–89. http://dx.doi.org/10.1515/znb-2009-0916.

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Two new metabolites, named crispacolide (1) and 3-acetyl-4-hydroxymethyl-tetrahydrofuran (2), were isolated from the fruiting bodies of basidiomycete Sparassis crispa (Wulf.) Fr. The structures and stereochemistry were established on the basis of spectroscopic means
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47

Pachaly, Peter, and Adek Z. Adnan. "Tinocrisposid, ein neues Furanoditerpenglykosid ausTinospora crispa Miers." Archiv der Pharmazie 325, no. 11 (1992): 705–8. http://dx.doi.org/10.1002/ardp.19923251105.

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48

Ahmad, Ijaz, Itrat Anis, Itrat Fatima, et al. "Two New Protease-Inhibiting Glycosphingolipids fromBuddleja crispa." Chemistry & Biodiversity 4, no. 5 (2007): 917–24. http://dx.doi.org/10.1002/cbdv.200790080.

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49

Jansakul, C., G. Samuelsson, H. Baumann, and L. Kenne. "Utero-Contracting Triterpene Saponins from Ardisia crispa." Planta Medica 52, no. 06 (1986): 544. http://dx.doi.org/10.1055/s-2007-969346.

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50

Noor, Hamdan, and Stephen J. H. Ashcroft. "Antidiabetic effects of Tinospora crispa in rats." Journal of Ethnopharmacology 27, no. 1-2 (1989): 149–61. http://dx.doi.org/10.1016/0378-8741(89)90087-1.

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