Dissertations / Theses on the topic 'CRISPR, Cas9, genome editing, gRNA'
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Roidos, Paris. "Genome editing with the CRISPR Cas9 system." Thesis, KTH, Skolan för bioteknologi (BIO), 2014. http://urn.kb.se/resolve?urn=urn:nbn:se:kth:diva-163694.
Full textRan, Fei Ann. "CRISPR-Cas: Development and applications for mammalian genome editing." Thesis, Harvard University, 2014. http://dissertations.umi.com/gsas.harvard:11610.
Full textHirosawa, Moe. "Cell-type-specific genome editing with a microRNA-responsive CRISPR-Cas9 switch." Kyoto University, 2019. http://hdl.handle.net/2433/242421.
Full textCastanon, velasco Oscar. "Targeting the transposable elements of the genome to enable large-scale genome editing and bio-containment technologies." Thesis, Université Paris-Saclay (ComUE), 2019. http://www.theses.fr/2019SACLX006.
Full textValladares, Rodrigo, and Hanna Briheim. "Metoder och tillämpningar av CRISPR-Cas9 i cancerforskning. : Samt hur CRISPR-Cas9 kan implementeras i skolundervisningen." Thesis, Linköpings universitet, Institutionen för fysik, kemi och biologi, 2020. http://urn.kb.se/resolve?urn=urn:nbn:se:liu:diva-166140.
Full textToffessi, Tcheuyap Vanina. "Development of von Willebrand Factor Zebrafish Mutant Using CRISPR/Cas9 Mediated Genome Editing." Thesis, University of North Texas, 2017. https://digital.library.unt.edu/ark:/67531/metadc984227/.
Full textCanver, Matthew. "Elucidation of Mechanisms of Fetal Hemoglobin Regulation by CRISPR/Cas9 Mediated Genome Editing." Thesis, Harvard University, 2016. http://nrs.harvard.edu/urn-3:HUL.InstRepos:33493407.
Full textAntoniani, Chiara. "A genome editing approach to induce fetal hemoglobin expression for the treatment of β-hemoglobinopathies". Thesis, Sorbonne Paris Cité, 2017. http://www.theses.fr/2017USPCB077.
Full textLin, ChieYu. "Characterization and Optimization of the CRISPR/Cas System for Applications in Genome Engineering." Thesis, Harvard University, 2014. http://etds.lib.harvard.edu/hms/admin/view/61.
Full textHsu, Patrick David. "Development of the CRISPR nuclease Cas9 for high precision mammalian genome engineering." Thesis, Harvard University, 2014. http://nrs.harvard.edu/urn-3:HUL.InstRepos:13068392.
Full textBolukbasi, Mehmet F. "Development of Chimeric Cas9 Nucleases for Accurate and Flexible Genome Editing." eScholarship@UMMS, 2017. https://escholarship.umassmed.edu/gsbs_diss/941.
Full textAmai, Takamitsu. "Development of genome editing technology of mitochondrial DNA in Saccharomyces cerevisiae." Doctoral thesis, Kyoto University, 2021. http://hdl.handle.net/2433/263707.
Full textJo, Norihide. "Platforms of in vivo genome editing with inducible Cas9 for advanced cancer modeling." Kyoto University, 2019. http://hdl.handle.net/2433/242397.
Full textFang, Yufeng. "Nuclear Localization of Proteins and Genome Editing in the Oomycete Phytophthora sojae." Diss., Virginia Tech, 2016. http://hdl.handle.net/10919/74232.
Full textFeehan, Joanna Marie. "Development of methodology for genome editing in Xenopus laevis using CRISPR/Cas9, targeting the rhodopsin gene." Thesis, University of British Columbia, 2016. http://hdl.handle.net/2429/57863.
Full textLam, Phuong T. "Crispr/cas9-mediated genome editing of human pluripotent stem cells to advance human retina regeneration research." Miami University / OhioLINK, 2019. http://rave.ohiolink.edu/etdc/view?acc_num=miami1575372014701457.
Full textKishimoto, Kenta. "Application of genome editing to marine aquaculture as a new breeding technology." Kyoto University, 2019. http://hdl.handle.net/2433/242704.
Full textXu, Huaigeng. "Targeted Disruption of HLA genes via CRISPR-Cas9 generates iPSCs with Enhanced Immune Compatibility." Kyoto University, 2019. http://hdl.handle.net/2433/242420.
Full textMosqueira, Diogo. "Disease modeling hypertrophic cardiomyopathy using CRISPR/Cas9 genome editing technology in human pluripotent stem cell-derived cardiomyocytes." Thesis, University of Nottingham, 2018. http://eprints.nottingham.ac.uk/51359/.
Full textCarstairs, Alice. "Development of in vitro skeletal disease models using CRISPR/Cas9 genome editing in immortalised mesenchymal stem cells." Thesis, University of York, 2017. http://etheses.whiterose.ac.uk/18513/.
Full textSchneider, Sara Jane. "Delivery of CRISPR/Cas9 RNAs into Blood Cells of Zebrafish: Potential for Genome Editing in Somatic Cells." Thesis, University of North Texas, 2017. https://digital.library.unt.edu/ark:/67531/metadc1011754/.
Full textVicencio, Jeremy 1990. "Optimizing CRISPR-Cas technologies in Caenorhabditis elegans : Nested CRISPR and expanded targeting with Cas variants." Doctoral thesis, TDX (Tesis Doctorals en Xarxa), 2021. http://hdl.handle.net/10803/672604.
Full textTennant, Peter Andrew. "Genome editing using site-specific nucleases : targeting highly expressed genomic regions for robust transgene expression and genetic analysis." Thesis, University of Edinburgh, 2016. http://hdl.handle.net/1842/22857.
Full textVitarelli, Marcela de Oliveira. "Humanização específica do sistema de glicosilação de Pichia pastoris pela técnica CRISPR/Cas9 visando a expressão de glicoproteínas humanas." Universidade de São Paulo, 2016. http://www.teses.usp.br/teses/disponiveis/46/46131/tde-11042017-084657/.
Full textAmaya, Colina Anais Karime. "Towards the Treatment of Human Genetic Liver Disease by AAV-Mediated Genome Editing and Selective Expansion of Repaired Hepatocytes." Thesis, The University of Sydney, 2019. https://hdl.handle.net/2123/21893.
Full textEdraki, Alireza. "Compact Cas9s and Their Natural Inhibitors for Genome Editing." eScholarship@UMMS, 2019. https://escholarship.umassmed.edu/gsbs_diss/1052.
Full textBressan, Raul Bardini. "Genome editing as a tool to explore transcriptional and epigenetic regulation in neural stem cells and brain cancer." Thesis, University of Edinburgh, 2018. http://hdl.handle.net/1842/31095.
Full textFine, Eli Jacob. "A toolkit for analysis of gene editing and off-target effects of engineered nucleases." Diss., Georgia Institute of Technology, 2015. http://hdl.handle.net/1853/54875.
Full textCharpentier, Marine. "Développement de nouvelles approches d’édition du génome à l’aide de nucléases artificielles (TALENs et CRISPR/Cas9)." Thesis, Paris, EPHE, 2016. http://www.theses.fr/2016EPHE3106/document.
Full textLLADO, SANTAEULARIA MANEL. "THERAPEUTIC GENOME EDITING IN RETINA AND LIVER." Doctoral thesis, Università degli Studi di Milano, 2020. http://hdl.handle.net/2434/696628.
Full textBallmann, Cora [Verfasser]. "Gezielte Sequenzierung von USP8 bei PatientInnen mit Morbus Cushing und Genome Editing in HAC15 Zellen mittels CRISPR/Cas9 / Cora Ballmann." Düsseldorf : Universitäts- und Landesbibliothek der Heinrich-Heine-Universität Düsseldorf, 2021. http://d-nb.info/1231075147/34.
Full textKapahnke, Marcel [Verfasser]. "Knock-out of Flotillins in Human Cells Using the CRISPR-Cas9 Genome Editing System: Effects on mRNA Splicing / Marcel Kapahnke." Gießen : Universitätsbibliothek, 2020. http://d-nb.info/1223462137/34.
Full textStringa, Blerta. "The effect of germline variants on the genesis of early somatic events in cancer explored via Cas9 genome editing." Doctoral thesis, Università degli studi di Trento, 2019. http://hdl.handle.net/11572/242372.
Full textStringa, Blerta. "The effect of germline variants on the genesis of early somatic events in cancer explored via Cas9 genome editing." Doctoral thesis, Università degli studi di Trento, 2019. http://hdl.handle.net/11572/242372.
Full textMurakami, Yu. "Establishment of a practical gene knock-in system and its application in medaka." Kyoto University, 2020. http://hdl.handle.net/2433/253339.
Full textMINGOIA, MAURA. "Terapia genica della β Talassemia mediante editing del DNA". Doctoral thesis, Università degli Studi di Cagliari, 2016. http://hdl.handle.net/11584/266632.
Full textBORRELLI, VIRGINIA MARIA GRAZIA. "Caratterizzazione del gene LIPOSSIGENASI 4 e approccio CRISPR-Cas9 per aumentare la resistenza alla fusariosi di mais." Doctoral thesis, Università Cattolica del Sacro Cuore, 2018. http://hdl.handle.net/10280/53792.
Full textBORRELLI, VIRGINIA MARIA GRAZIA. "Caratterizzazione del gene LIPOSSIGENASI 4 e approccio CRISPR-Cas9 per aumentare la resistenza alla fusariosi di mais." Doctoral thesis, Università Cattolica del Sacro Cuore, 2018. http://hdl.handle.net/10280/53792.
Full textIbraheim, Raed R. "Genome Engineering Goes Viral: Repurposing of Adeno-associated Viral Vectors for CRISPR-mediated in Vivo Genome Engineering." eScholarship@UMMS, 2020. https://escholarship.umassmed.edu/gsbs_diss/1114.
Full textJanin, Grajcarek. "Genome-wide microhomologies enable precise template-free editing of biologically relevant deletion mutations." Kyoto University, 2020. http://hdl.handle.net/2433/253215.
Full textFoster, Robert Graham. "Development of a modular in vivo reporter system for CRISPR-mediated genome editing and its therapeutic applications for rare genetic respiratory diseases." Thesis, University of Edinburgh, 2018. http://hdl.handle.net/1842/33040.
Full textMarco, Giménez Andrés 1993. "Generation and validation of a CRISPR platform for rapid and inducible genome editing in human pluripotent stem cells and kidney organoids." Doctoral thesis, TDX (Tesis Doctorals en Xarxa), 2022. http://hdl.handle.net/10803/673798.
Full textHahn, Florian [Verfasser], Andreas P. M. [Gutachter] Weber, and Peter [Gutachter] Westhoff. "Genome editing and establishment of efficient gene targeting approaches in Arabidopsis using the CRISPR/Cas9 system / Florian Hahn ; Gutachter: Andreas P. M. Weber, Peter Westhoff." Düsseldorf : Universitäts- und Landesbibliothek der Heinrich-Heine-Universität Düsseldorf, 2018. http://d-nb.info/1159373612/34.
Full textSürün, Duran [Verfasser], Beatrix [Akademischer Betreuer] Süß, M. Cristina [Akademischer Betreuer] Cardoso, and Harald von [Akademischer Betreuer] Melchner. "High Efficiency Gene Correction in Hematopoietic Cells by Donor Template-free CRISPR/Cas9 Genome Editing / Duran Sürün ; Beatrix Süß, M. Cristina Cardoso, Harald von Melchner." Darmstadt : Universitäts- und Landesbibliothek Darmstadt, 2018. http://d-nb.info/1153546396/34.
Full textPröbsting, Michael Verfasser], Daguang [Akademischer Betreuer] [Cai, and Christian [Gutachter] Jung. "Application of CRISPR-Cas9 genome editing systems for improving oilseed rape (Brassica napus) disease resistance against Verticillium longisporum / Michael Pröbsting ; Gutachter: Christian Jung ; Betreuer: Daguang Cai." Kiel : Universitätsbibliothek Kiel, 2020. http://nbn-resolving.de/urn:nbn:de:gbv:8-mods-2020-00084-7.
Full textPröbsting, Michael [Verfasser], Daguang [Akademischer Betreuer] Cai, and Christian [Gutachter] Jung. "Application of CRISPR-Cas9 genome editing systems for improving oilseed rape (Brassica napus) disease resistance against Verticillium longisporum / Michael Pröbsting ; Gutachter: Christian Jung ; Betreuer: Daguang Cai." Kiel : Universitätsbibliothek Kiel, 2020. http://d-nb.info/120658887X/34.
Full textCarayon, Alexandre. "Mise en place de l'identité musculaire durant la myogenèse embryonnaire chez la drosophile." Thesis, Toulouse 3, 2018. http://www.theses.fr/2018TOU30107.
Full textYoussef, Divana. "Recherches de méthodes innovantes issues des biotechnologies pour l'amélioration génétique du blé tendre (Triticum aestivum L.)." Thesis, Université Clermont Auvergne (2017-2020), 2017. http://www.theses.fr/2017CLFAC054.
Full textStens, Cassandra, Isabella Enoksson, and Sara Berggren. "The CRISPR-Cas system." Thesis, Linköpings universitet, Institutionen för fysik, kemi och biologi, 2020. http://urn.kb.se/resolve?urn=urn:nbn:se:liu:diva-171997.
Full textRabai, Aymen. "Correction de l'ADN in vitro et in vivo comme thérapie personnalisée pour les myopathies congénitales." Thesis, Strasbourg, 2018. http://www.theses.fr/2018STRAJ117.
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