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Journal articles on the topic 'CRM channels'

Author: Grafiati

Published: 4 June 2021

Last updated: 10 February 2022

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1

Chen, Liwei, J. J. Po-An Hsieh, Arun Rai, and Sean Xin Xu. "How Does Employee Infusion Use of CRM Systems Drive Customer Satisfaction? Mechanism Differences Between Face-to-Face and Virtual Channels." MIS Quarterly 45, no. 2 (2021): 719–54. http://dx.doi.org/10.25300/misq/2021/13265.

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To attain customer satisfaction, service firms invest significant resources to implement customer relationship management (CRM) systems to support internal customer service (CS) employees who provide service to external customers in both face-to-face and virtual channels. How CS employees apply sophisticated CRM systems to interact with customers and how the mechanisms through which their CRM usage affects customer satisfaction vary across service channels and bear important implications. We approach these issues by investigating the concept of infusion use, defined as CS employees’ assessment

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Potra, Sabina, Monica Izvercian, and Serban Miclea. "Changes in CRM Approach." International Journal of Information Systems in the Service Sector 8, no. 1 (2016): 45–57. http://dx.doi.org/10.4018/ijisss.2016010104.

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Relationship marketing principles shifted with the emergence of the social Web. The firm-centric, traditional closed doors approach is no longer assuring the survival in a global market with demanding and informed customers. Customer touch points are replaced by an open mentality where customer experience and creative collaboration with prosumers has changed even CRM techniques. The present paper analyses the journey from traditional CRM, to social CRM and PoRM (Prosumer-oriented Relationship Management) in response to consumer creative engagement desires. Thus, four PoRM processes are concept

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Aduski, Erlina, Prasetyo Hadi, and Rusdi Musa Ishaq. "Analisis Strategi Pemasaran Produk Digital CRM di PT Infomedia Nusantara." MBIA 19, no. 2 (2020): 153–69. http://dx.doi.org/10.33557/mbia.v19i2.892.

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The purpose of this research is to reformulate the marketing strategy of Digital CRM products where at this time, in the digital era, the contribution of revenue generated by CRM Digital is still very low if we compared with Inbound Call (Legacy CRM). This research applied the qualitative approach with a descriptive type of research and using PEST analysis, Industry Environment 5 Forces Porter Analysis, SWOT, and 7P Marketing Mix. Based on the analysis of external and internal factors, we get several alternative strategies such as 1) Product: focus on offering Integrated Omnichannel products,

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Lipiäinen, Heini Sisko Maarit. "CRM in the digital age: implementation of CRM in three contemporary B2B firms." Journal of Systems and Information Technology 17, no. 1 (2015): 2–19. http://dx.doi.org/10.1108/jsit-06-2014-0044.

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Purpose – The purpose of this study was to contribute to the current discussion on digitization in companies’ marketing from a customer relationship management (CRM) perspective by examining the role and objectives of CRM and the exploitation of social media to serve the objectives of CRM in contemporary business-to-business (B2B) companies. Design/methodology/approach – The data are collected through semi-structured themed interviews with key marketing/sales managers from three B2B firms. Findings – CRM seems to be moving closer to the company’s core activity and becoming everybody’s business

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Paliouras, Konstantinos, and Kerstin V. Siakas. "Social Customer Relationship Management: A Case Study." International Journal of Entrepreneurial Knowledge 5, no. 1 (2017): 20–34. http://dx.doi.org/10.1515/ijek-2017-0002.

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Abstract Social Customer Relationships Management (CRM) is a current business trend providing new channels of two-way communication with customers through social media sites, such as Facebook, Twitter etc. Social CRM enables companies to interact in an easy and contemporary way directly with customers as well as to track customer interactions and their social influence. In this paper we examine the importance of CRM, e-CRM and Social CRM for businesses. We provide perspectives on objectives and types of CRM, the working cycle of CRM, the stages of a CRM Strategy and technology tools that are u

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Shankar, Venky. "Big Data and Analytics in Retailing." NIM Marketing Intelligence Review 11, no. 1 (2019): 36–40. http://dx.doi.org/10.2478/nimmir-2019-0006.

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AbstractBig data are taking center stage for decision-making in many retail organizations. Customer data on attitudes and behavior across channels, touchpoints, devices and platforms are often readily available and constantly recorded. These data are integrated from multiple sources and stored or warehoused, often in a cloud-based environment. Statistical, econometric and data science models are developed for enabling appropriate decisions. Computer algorithms and programs are created for these models. Machine learning based models, are particularly useful for learning from the data and making

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De Juan-Jordán, Hugo, María Guijarro-García, and Javier Hernandez Gadea. "Feature Analysis of the “Customer Relationship Management” Systems for Higher Education Institutions." Multidisciplinary Journal for Education, Social and Technological Sciences 5, no. 1 (2018): 30. http://dx.doi.org/10.4995/muse.2018.9232.

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<p class="Textoindependiente21">Universities, business schools and other higher education institutions all over the world are experiencing deep changes in the way they work and interrelate with their ‘clients’, i.e. students and their relatives, alumni and donors, faculty and staff members, because these constituents are demanding more attention through different channels as well as immediate response and service. Technology - materialized in the form of Customer Relationship Management (CRM) systems - is the great promise for solving these demands.</p>This article summarizes the f

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Varis, Iryna, Oksana Kravchuk, and Sofiia Zavhorodnia. "Business’s digital transformation: choice, implementation and improvement of CRM-systems." Marketing and Digital Technologies 5, no. 2 (2021): 48–66. http://dx.doi.org/10.15276/mdt.5.2.2021.5.

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The aim of the article. The aim of the article is to determine the essence, advantages and disadvantages of business’s digital transformation, describe the importance of business-process management through its digital transformation, define the nature, types and capabilities of CRM-systems, identify and describe trends in their development, analyze the results of prior researches and select the most popular CRM-systems, as well as research for existing problems of using defined CRM-systems, suggest recommendations for eliminating shortcomings of existing CRM-systems. Analyses results. The coro

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BURKART, PATRICK, and TOM McCOURT. "Infrastructure for the Celestial Jukebox." Popular Music 23, no. 3 (2004): 349–62. http://dx.doi.org/10.1017/s0261143004000236.

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The vision of a dynamic and intelligent Celestial Jukebox, in which any cultural artifact is available to dedicated appliances or home computers via wired or wireless channels, animates many predictions for the future of media delivery. The chief proponents of this vision are transnational media firms selling hardware, software and content. Despite a prolonged downturn in the global economy for media and software, the technical and legal design of the Celestial Jukebox nears completion. We examine the development and implications of the Jukebox as it is manifested in several online music servi

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Valacherry, Arunima Kambikanon, and Pakkeerappagari Pakkeerappa. "Customer Knowledge Management via Social Media: A Case Study of an Indian Retailer." Journal of Human Values 24, no. 1 (2017): 39–55. http://dx.doi.org/10.1177/0971685817733571.

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The socialization process in knowledge management (KM) has been in discussion for more than a decade, and most research has focused on socialization among employees in developing organizational knowledge. But this article tries to explore the socialization aspect in customer knowledge management (CKM) in a customer-centric industry, retail using social media. The case study of a leading Indian retailer is implemented using netnography, a research technique that draws data from computer-mediated communication channels. The communications of the retailer to and from customers through Facebook, T

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Koide, Masayo, Paul L. Penar, Bruce I. Tranmer, and George C. Wellman. "Heparin-binding EGF-like growth factor mediates oxyhemoglobin-induced suppression of voltage-dependent potassium channels in rabbit cerebral artery myocytes." American Journal of Physiology-Heart and Circulatory Physiology 293, no. 3 (2007): H1750—H1759. http://dx.doi.org/10.1152/ajpheart.00443.2007.

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Oxyhemoglobin (OxyHb) can suppress voltage-dependent K+ channel (KV) currents through protein tyrosine kinase activation, which may contribute to cerebral vasospasm following subarachnoid hemorrhage. Here we have tested the hypothesis that shedding of heparin-binding EGF-like growth factor (HB-EGF) and the resulting activation of the tyrosine kinase EGF receptor (EGFR) underlie OxyHb-induced KV channel suppression in the cerebral vasculature. With the use of the conventional whole cell patch-clamp technique, two EGFR ligands, EGF and HB-EGF, were found to mimic OxyHb-induced KV suppression in

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Kosch, Lubov, Ina Friedrich, and Michael H. Breitner. "Evaluating Customer Relationship Management in the Context of Higher Education." International Journal of Social and Organizational Dynamics in IT 2, no. 1 (2012): 32–52. http://dx.doi.org/10.4018/ijsodit.2012010103.

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The current economic climate has its effect on the higher education sector as less money is provided by governments and increasing number of students with higher demands and expectations intensify competition among universities. Customer relationship management (CRM) has become a key instrument in attracting paying students as retaining a long-lasting relationship provides financial and other benefits. This paper presents a structured literature review to analyze requirements for a student relationship management system (SRMS) as discussed in literature and analyzes the findings with results g

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Holanda, Rafael, Eduardo Gildin, Jerry Jensen, Larry Lake, and C. Kabir. "A State-of-the-Art Literature Review on Capacitance Resistance Models for Reservoir Characterization and Performance Forecasting." Energies 11, no. 12 (2018): 3368. http://dx.doi.org/10.3390/en11123368.

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Capacitance resistance models (CRMs) comprise a family of material balance reservoir models that have been applied to primary, secondary and tertiary recovery processes. CRMs predict well flow rates based solely on previously observed production and injection rates, and producers’ bottomhole pressures (BHPs); i.e., a geological model and rock/fluid properties are not required. CRMs can accelerate the learning curve of the geological analysis by providing interwell connectivity maps to corroborate features such as sealing faults and channels, as well as diagnostic plots to determine sweep effic

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Charles, S. A., E. A. Ball, T. H. Whittaker, and J. K. Pollard. "Channel sounder for 5.5 GHz wireless channels." IEE Proceedings - Communications 150, no. 4 (2003): 253. http://dx.doi.org/10.1049/ip-com:20030356.

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Țoniș-Bucea-Manea, Rocsana, and Ovidiu Blăjină. "Factors Influencing Online Consumer Behavior in the Era of IoT." Materials Science Forum 957 (June 2019): 81–89. http://dx.doi.org/10.4028/www.scientific.net/msf.957.81.

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Consumers feels the fulminate evolution of internet and technologies in everyday life, in the personal devices interconnected with (mobiles, tables, cars). The IoT (internet of things) changes the houses and institutions activities, or holiday services, etc. This trend is present in every field of the current digital economy, too, bringing new devices and modalities of online marketing, such as virtual reality and augmented reality. This is the reason that each company has to face the challenge by having a constant open communication with the consumers, taking advantage of the new technologies

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Godin, V. V., and A. E. Terekhova. "Digital advertising as a tool to promote goods or services. Project implementation experience." E-Management 2, no. 3 (2019): 13–21. http://dx.doi.org/10.26425/2658-3445-2019-3-13-21.

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The article has been devoted to theoretical issues of the digital advertising sphere, its tasks and features. The online advertising market development level has been estimated, based on analytical data. Digital advertising is a complex of analytical, technological and supporting tools, which are interconnected directly. It includes a system of methods and tools, which use digital channels to promote a product or brand, attract and retain customers. The main areas of digital advertising are display advertising, banner advertising, video advertising and contextual advertising. Digital advertisi

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Li, Weiyan, David B. Halling, Amelia W. Hall, and Richard W. Aldrich. "EF hands at the N-lobe of calmodulin are required for both SK channel gating and stable SK–calmodulin interaction." Journal of General Physiology 134, no. 4 (2009): 281–93. http://dx.doi.org/10.1085/jgp.200910295.

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Small conductance calcium-activated potassium (SK) channels respond to intracellular Ca2+ via constitutively associated calmodulin (CaM). Previous studies have proposed a modular design for the interaction between CaM and SK channels. The C-lobe and the linker of CaM are thought to regulate the constitutive binding, whereas the N-lobe binds Ca2+ and gates SK channels. However, we found that coexpression of mutant CaM (E/Q) where the N-lobe has only one functional EF hand leads to rapid rundown of SK channel activity, which can be recovered with exogenously applied wild-type (WT), but not mutan

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18

Chakouri, Nourdine, Johanna Diaz, Philemon S. Yang, and Manu Ben-Johny. "CaV channels reject signaling from a second CaM in eliciting Ca2+-dependent feedback regulation." Journal of Biological Chemistry 295, no. 44 (2020): 14948–62. http://dx.doi.org/10.1074/jbc.ra120.013777.

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Calmodulin (CaM) regulation of voltage-gated calcium (CaV1-2) channels is a powerful Ca2+-feedback mechanism to adjust channel activity in response to Ca2+ influx. Despite progress in resolving mechanisms of CaM-CaV feedback, the stoichiometry of CaM interaction with CaV channels remains ambiguous. Functional studies that tethered CaM to CaV1.2 suggested that a single CaM sufficed for Ca2+ feedback, yet biochemical, FRET, and structural studies showed that multiple CaM molecules interact with distinct interfaces within channel cytosolic segments, suggesting that functional Ca2+ regulation may

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Bidabad, Bijan, and Mahmoud Allahyarifard. "IT Role in Fulfillment of Profit & Loss Sharing (PLS) Mechanism." International Journal of Islamic Banking and Finance Research 3, no. 2 (2019): 44–59. http://dx.doi.org/10.46281/ijibfr.v3i2.274.

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In this paper, we are going to introduce a new IT master solution to improve non-usury banking performance. All divine religions emphasize on usury prohibition. It is concluded that with some IT solutions, it may be possible to fulfill the worldly requirement by use of IT systems without any incredulity. Since depositors are shareholders of Non-Usury Bank Corporation (NU Bank Co), therefore integrated information systems can provide suitable infrastructure for transactions recording and management done by all participants' chains; and the end of process the yields of investment capital of depo

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Akhbari, B., M. R. Aref, and R. Khosravi-Farsani. "Cooperative relay broadcast channels with partial causal channel state information." IET Communications 5, no. 6 (2011): 760–74. http://dx.doi.org/10.1049/iet-com.2010.0093.

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21

Trudeau, Matthew C., and William N. Zagotta. "Dynamics of Ca2+-Calmodulin–dependent Inhibition of Rod Cyclic Nucleotide-gated Channels Measured by Patch-clamp Fluorometry." Journal of General Physiology 124, no. 3 (2004): 211–23. http://dx.doi.org/10.1085/jgp.200409101.

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Cyclic nucleotide-gated (CNG) ion channels mediate cellular responses to sensory stimuli. In vertebrate photoreceptors, CNG channels respond to the light-induced decrease in cGMP by closing an ion-conducting pore that is permeable to cations, including Ca2+ ions. Rod CNG channels are directly inhibited by Ca2+-calmodulin (Ca2+/CaM), but the physiological role of this modulation is unknown. Native rod CNG channels comprise three CNGA1 subunits and one CNGB1 subunit. The single CNGB1 subunit confers several key properties on heteromeric channels, including Ca2+/CaM-dependent modulation. The mole

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Li, Qiang, Kwok Hung Li, and Kah Chan Teh. "Low-complexity channel estimation and turbo equalisation for high frequency channels." IET Communications 7, no. 10 (2013): 980–87. http://dx.doi.org/10.1049/iet-com.2012.0811.

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Gappmair, Wilfried, and Michael Bergmann. "Estimation of carrier and channel parameters in time-selective fading channels." IET Communications 9, no. 12 (2015): 1474–78. http://dx.doi.org/10.1049/iet-com.2015.0080.

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Choi, J. "Multipath CDMA channel estimation by jointly utilising pilot and traffic channels." IEE Proceedings - Communications 146, no. 5 (1999): 312. http://dx.doi.org/10.1049/ip-com:19990622.

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Kang, Y., K. Kim, and H. Park. "Efficient DFT-based channel estimation for OFDM systems on multipath channels." IET Communications 1, no. 2 (2007): 197. http://dx.doi.org/10.1049/iet-com:20050337.

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Efthymoglou, G. P., N. Y. Ermolova, and V. A. Aalo. "Channel capacity and average error rates in generalised-K fading channels." IET Communications 4, no. 11 (2010): 1364. http://dx.doi.org/10.1049/iet-com.2009.0457.

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Black, D. J., D. Brent Halling, David V. Mandich, Steen E. Pedersen, Ruth A. Altschuld, and Susan L. Hamilton. "Calmodulin interactions with IQ peptides from voltage-dependent calcium channels." American Journal of Physiology-Cell Physiology 288, no. 3 (2005): C669—C676. http://dx.doi.org/10.1152/ajpcell.00191.2004.

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Calmodulin (CaM) functions as a Ca2+ sensor for inactivation and, in some cases, facilitation of a variety of voltage-dependent Ca2+ channels. A crucial determinant for CaM binding to these channels is the IQ motif in the COOH-terminal tail of the channel-forming subunit. The binding of CaM to IQ peptides from Lc-, P/Q-, and R-type, but not N-type, voltage-dependent Ca2+ channels increases the Ca2+ affinity of both lobes of CaM, producing similar N- and C-lobe Ca2+ affinities. Ca2+ associates with and dissociates from the N-lobe much more rapidly than the C-lobe when CaM is bound to the IQ pep

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Chaudhuri, Dipayan, John B. Issa, and David T. Yue. "Elementary Mechanisms Producing Facilitation of Cav2.1 (P/Q-type) Channels." Journal of General Physiology 129, no. 5 (2007): 385–401. http://dx.doi.org/10.1085/jgp.200709749.

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The regulation of CaV2.1 (P/Q-type) channels by calmodulin (CaM) showcases the powerful Ca2+ decoding capabilities of CaM in complex with the family of CaV1-2 Ca2+ channels. Throughout this family, CaM does not simply exert a binary on/off regulatory effect; rather, Ca2+ binding to either the C- or N-terminal lobe of CaM alone can selectively trigger a distinct form of channel modulation. Additionally, Ca2+ binding to the C-terminal lobe triggers regulation that appears preferentially responsive to local Ca2+ influx through the channel to which CaM is attached (local Ca2+ preference), whereas

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Yao, Rugui, Yinsheng Liu, Juan Xu, and Geng Li. "Channel estimation for orthogonal frequency division multiplexing uplinks in time-varying channels." IET Communications 9, no. 2 (2015): 156–66. http://dx.doi.org/10.1049/iet-com.2014.0551.

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Yu, Baoxian, Han Zhang, Xudong Hong, et al. "Channel equalisation and data detection for SEFDM over frequency selective fading channels." IET Communications 12, no. 18 (2018): 2315–23. http://dx.doi.org/10.1049/iet-com.2018.5114.

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Sun, Dajun, Xiaoping Hong, Hongyu Cui, and Lu Liu. "Iterative multi-channel FH-MFSK reception in mobile shallow underwater acoustic channels." IET Communications 14, no. 5 (2020): 838–45. http://dx.doi.org/10.1049/iet-com.2019.1045.

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Zarimpas, V., B. Honary, and M. Darnell. "Channel adaptive multiple I∕O protocol for mixed wireless and wired channels." IET Communications 1, no. 5 (2007): 982. http://dx.doi.org/10.1049/iet-com:20060355.

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Xu, Ping, Xiao Mo, Ruixue Xia, et al. "KCNN4 promotes the progression of lung adenocarcinoma by activating the AKT and ERK signaling pathways." Cancer Biomarkers 31, no. 2 (2021): 187–201. http://dx.doi.org/10.3233/cbm-201045.

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BACKGROUND: Potassium channels, encoded by more than seventy genes, are cell excitability transmembrane proteins and become evident to play essential roles in tumor biology. OBJECTIVE: The deregulation of potassium channel genes has been related to cancer development and patient prognosis. The objective of this study is to understand the role of potassium channels in lung cancer. METHODS: We examined all potassium channel genes and identified that KCNN4 is the most significantly overexpressed one in lung adenocarcinoma. The role and mechanism of KCNN4 in lung adenocarcinoma were further invest

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Xu, Jian-Jun, Li-Ying Hao, Asako Kameyama, and Masaki Kameyama. "Calmodulin reverses rundown of L-type Ca2+ channels in guinea pig ventricular myocytes." American Journal of Physiology-Cell Physiology 287, no. 6 (2004): C1717—C1724. http://dx.doi.org/10.1152/ajpcell.00105.2004.

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Calmodulin (CaM) is implicated in regulation of Ca2+ channels as a Ca2+ sensor. The effect of CaM on rundown of L-type Ca2+ channels in inside-out patch form was investigated in guinea pig ventricular myocytes. Ca2+ channel activity disappeared within 1–3 min and did not reappear when the patch was excised and exposed to an artificial intracellular solution. However, application of CaM (0.03, 0.3, 3 μM) + 3 mM ATP to the intracellular solution within 1 min after patch excision resulted in dose-dependent activation of channel activity. Channel activity averaged 11.2%, 94.7%, and 292.9%, respect

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Jara-Oseguera, Andrés, Itzel G. Ishida, Gisela E. Rangel-Yescas, et al. "Uncoupling Charge Movement from Channel Opening in Voltage-gated Potassium Channels by Ruthenium Complexes." Journal of Biological Chemistry 286, no. 18 (2011): 16414–25. http://dx.doi.org/10.1074/jbc.m110.198010.

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The Kv2.1 channel generates a delayed-rectifier current in neurons and is responsible for modulation of neuronal spike frequency and membrane repolarization in pancreatic β-cells and cardiomyocytes. As with other tetrameric voltage-activated K+-channels, it has been proposed that each of the four Kv2.1 voltage-sensing domains activates independently upon depolarization, leading to a final concerted transition that causes channel opening. The mechanism by which voltage-sensor activation is coupled to the gating of the pore is still not understood. Here we show that the carbon-monoxide releasing

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Rodrat, Mayuree, Walailak Jantarajit, Demi R. S. Ng, et al. "Carbon monoxide-releasing molecules inhibit the cystic fibrosis transmembrane conductance regulator Cl− channel." American Journal of Physiology-Lung Cellular and Molecular Physiology 319, no. 6 (2020): L997—L1009. http://dx.doi.org/10.1152/ajplung.00440.2019.

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The gasotransmitter carbon monoxide (CO) regulates fluid and electrolyte movements across epithelial tissues. However, its action on anion channels is incompletely understood. Here, we investigate the direct action of CO on the cystic fibrosis transmembrane conductance regulator (CFTR) by applying CO-releasing molecules (CO-RMs) to the intracellular side of excised inside-out membrane patches from cells heterologously expressing wild-type human CFTR. Addition of increasing concentrations of tricarbonyldichlororuthenium(II) dimer (CORM-2) (1–300 μM) inhibited CFTR channel activity, whereas the

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Zhou, Wen. "Precoding methods for multi-input multi-ouput interference channels with channel covariance Feedback." IET Communications 9, no. 4 (2015): 517–25. http://dx.doi.org/10.1049/iet-com.2014.0636.

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Ogundile, Olayinka Olaolu, Olutayo Oyeyemi Oyerinde, and Daniel J. J. Versfeld. "Decision directed iterative channel estimation and Reed–Solomon decoding over flat fading channels." IET Communications 9, no. 17 (2015): 2077–84. http://dx.doi.org/10.1049/iet-com.2015.0234.

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Toker, C., S. Lambotharan, J. A. Chambers, and B. Baykal. "Joint spatial and temporal channel-shortening techniques for frequency selective fading MIMO channels." IEE Proceedings - Communications 152, no. 1 (2005): 89. http://dx.doi.org/10.1049/ip-com:20040965.

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Rontogiannis, A. A., and K. Berberidis. "Bandwidth efficient transmission through sparse channels using a parametric channel-estimation-based DFE." IEE Proceedings - Communications 152, no. 2 (2005): 251. http://dx.doi.org/10.1049/ip-com:20040970.

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Banerjee, Rahul, Jesse B. Yoder, David T. Yue, et al. "Bilobal architecture is a requirement for calmodulin signaling to CaV1.3 channels." Proceedings of the National Academy of Sciences 115, no. 13 (2018): E3026—E3035. http://dx.doi.org/10.1073/pnas.1716381115.

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Calmodulin (CaM) regulation of voltage-gated calcium (CaV) channels is a powerful Ca2+ feedback mechanism that adjusts Ca2+ influx, affording rich mechanistic insights into Ca2+ decoding. CaM possesses a dual-lobed architecture, a salient feature of the myriad Ca2+-sensing proteins, where two homologous lobes that recognize similar targets hint at redundant signaling mechanisms. Here, by tethering CaM lobes, we demonstrate that bilobal architecture is obligatory for signaling to CaV channels. With one lobe bound, CaV carboxy tail rearranges itself, resulting in a preinhibited configuration pre

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Bowley, Kate A., and Geoffrey I. Sandle. "Calmodulin Antagonist W-7 Enhances Intermediate Conductance Ca2+- Sensitive Basolateral Potassium Channel (IKCa) Activity in Human Colonic Crypts." Journal of Membrane Biology 254, no. 4 (2021): 423–28. http://dx.doi.org/10.1007/s00232-021-00193-y.

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AbstractIntermediate conductance potassium (IKCa) channels are exquisitively Ca2+ sensitive, intracellular Ca2+ regulating channel activity by complexing with calmodulin (CaM), which is bound to the cytosolic carboxyl tail. Although CaM antagonists might be expected to decrease IKCa channel activity, the effect of W-7 in human T lymphocytes are conflicting. We therefore evaluated the effect of W-7 on basolateral IKCa channels in human colonic crypt cells. Intact crypts obtained from normal human colonic biopsies by Ca2+ chelation were used for patch clamp studies of basolateral IKCa channels i

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Cai, Yuanzhi, Hong Huang, Kaiyang Wang, Cheng Zhang, Lei Fan, and Fangyu Guo. "Selecting Optimal Combination of Data Channels for Semantic Segmentation in City Information Modelling (CIM)." Remote Sensing 13, no. 7 (2021): 1367. http://dx.doi.org/10.3390/rs13071367.

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Over the last decade, a 3D reconstruction technique has been developed to present the latest as-is information for various objects and build the city information models. Meanwhile, deep learning based approaches are employed to add semantic information to the models. Studies have proved that the accuracy of the model could be improved by combining multiple data channels (e.g., XYZ, Intensity, D, and RGB). Nevertheless, the redundant data channels in large-scale datasets may cause high computation cost and time during data processing. Few researchers have addressed the question of which combina

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Wu, Xin, and Liang Hong. "Calmodulin Interactions with Voltage-Gated Sodium Channels." International Journal of Molecular Sciences 22, no. 18 (2021): 9798. http://dx.doi.org/10.3390/ijms22189798.

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Calmodulin (CaM) is a small protein that acts as a ubiquitous signal transducer and regulates neuronal plasticity, muscle contraction, and immune response. It interacts with ion channels and plays regulatory roles in cellular electrophysiology. CaM modulates the voltage-gated sodium channel gating process, alters sodium current density, and regulates sodium channel protein trafficking and expression. Many mutations in the CaM-binding IQ domain give rise to diseases including epilepsy, autism, and arrhythmias by interfering with CaM interaction with the channel. In the present review, we discus

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Biswas, Subrata, Isabelle Deschênes, Deborah DiSilvestre, Yanli Tian, Victoria L. Halperin, and Gordon F. Tomaselli. "Calmodulin Regulation of NaV1.4 Current: Role of Binding to the Carboxyl Terminus." Journal of General Physiology 131, no. 3 (2008): 197–209. http://dx.doi.org/10.1085/jgp.200709863.

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Calmodulin (CaM) regulates steady-state inactivation of sodium currents (NaV1.4) in skeletal muscle. Defects in Na current inactivation are associated with pathological muscle conditions such as myotonia and paralysis. The mechanisms of CaM modulation of expression and function of the Na channel are incompletely understood. A physical association between CaM and the intact C terminus of NaV1.4 has not previously been demonstrated. FRET reveals channel conformation-independent association of CaM with the C terminus of NaV1.4 (CT-NaV1.4) in mammalian cells. Mutation of the NaV1.4 CaM-binding IQ

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Chikha, Haithem Ben, Marion Berbineau, and Iyad Dayoub. "Distributed turbo coded cooperative networks under imperfect channel state information in Rayleigh fading channels." IET Communications 7, no. 10 (2013): 973–79. http://dx.doi.org/10.1049/iet-com.2012.0519.

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Sheu, Jeng-Shin, Wern-Ho Sheen, Chao-Kai Wu, and Hong-Rui Chang. "Pilot decontamination techniques based on beam-domain channel characteristics in millimetre-wave sparse channels." IET Communications 12, no. 19 (2018): 2493–501. http://dx.doi.org/10.1049/iet-com.2018.5107.

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Kiseleva, E. G. "The Impact of Digital Transformation on the Investment Potential of the Russian Cities." Finance: Theory and Practice 24, no. 5 (2020): 72–83. http://dx.doi.org/10.26794/2587-5671-2020-24-5-72-83.

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The digital transformation of all socio-economic spheres of the country determines the inclusion of digital factors in the assessment of investment potential. The aim of this paper is to justify the need to include digital factors in assessing the investment potential and the assessment of the digital potential of St. Petersburg. The study includes statistical methods of correlation analysis, average values, comparison, and grouping. This paper defines the concept of digital potential; highlights indicators of digital technology development; presents a methodology and assessment of the digital

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Gamper, Nikita, Yang Li, and Mark S. Shapiro. "Structural Requirements for Differential Sensitivity of KCNQ K+ Channels to Modulation by Ca2+/Calmodulin." Molecular Biology of the Cell 16, no. 8 (2005): 3538–51. http://dx.doi.org/10.1091/mbc.e04-09-0849.

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Calmodulin modulation of ion channels has emerged as a prominent theme in biology. The sensitivity of KCNQ1–5 K+ channels to modulation by Ca2+/calmodulin (CaM) was studied using patch-clamp, Ca2+ imaging, and biochemical and pharmacological approaches. Coexpression of CaM in Chinese hamster ovary (CHO) cells strongly reduced currents of KCNQ2, KCNQ4, and KCNQ5, but not KCNQ1 or KCNQ3. In simultaneous current recording/Ca2+ imaging experiments, CaM conferred Ca2+ sensitivity to KCNQ4 and KCNQ5, but not to KCNQ1, KCNQ3, or KCNQ1/KCNE1 channels. A chimera constructed from the carboxy terminus of

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Huang, M., X. Chen, L. Xiao, S. Zhou, and J. Wang. "Kalman-filter-based channel estimation for orthogonal frequency-division multiplexing systems in time-varying channels." IET Communications 1, no. 4 (2007): 795. http://dx.doi.org/10.1049/iet-com:20070039.

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