Log in

Relevant bibliographies by topics / Crosslinking mass spectrometry / Dissertations / Theses

To see the other types of publications on this topic, follow the link: Crosslinking mass spectrometry.

Dissertations / Theses on the topic 'Crosslinking mass spectrometry'

Author: Grafiati

Published: 15 June 2024

Last updated: 31 July 2025

Create a spot-on reference in APA, MLA, Chicago, Harvard, and other styles

Select a source type:

Consult the top 19 dissertations / theses for your research on the topic 'Crosslinking mass spectrometry.'

Next to every source in the list of references, there is an 'Add to bibliography' button. Press on it, and we will generate automatically the bibliographic reference to the chosen work in the citation style you need: APA, MLA, Harvard, Chicago, Vancouver, etc.

You can also download the full text of the academic publication as pdf and read online its abstract whenever available in the metadata.

Browse dissertations / theses on a wide variety of disciplines and organise your bibliography correctly.

1

Taverner, Thomas. "Protein complex architecture from mass spectrometry, crosslinking and informatics." Thesis, University of Cambridge, 2007. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.612836.

Full text

APA, Harvard, Vancouver, ISO, and other styles

2

Mak, Esther W. M. "Using Chemical Crosslinking and Mass Spectrometry for Protein Model Validation and Fold Recognition." Thesis, University of Waterloo, 2006. http://hdl.handle.net/10012/1228.

Full text

Abstract:

The 3D structures of proteins may provide important clues to their functions and roles in complex biological pathways. Traditional methods such as X-ray crystallography and NMR are not feasible for all proteins, while theoretical models are typically not validated by experimental data. This project investigates the use of chemical crosslinkers as an experimental means of validating these models. Five target proteins were successfully purified from yeast whole cell extract: Transketolase (TKL1), inorganic pyrophosphatase (IPP1), amidotransferase/cyclase HIS7, phosphoglycerate kinase (PGK

APA, Harvard, Vancouver, ISO, and other styles

3

Braun, Craig Ronald. "Structural Characterization of BCL-2 Family Protein Interactions Using Photoreactive Stapled Peptides and Mass Spectrometry." Thesis, Harvard University, 2012. http://dissertations.umi.com/gsas.harvard:10139.

Full text

Abstract:

Recent improvements in mass spectrometry instrumentation have stimulated the fusion of this technology with protein crosslinking to advance the structural proteomics field. However, analysis of complex datasets from crosslinking experiments remains a bottleneck. The majority of crosslinking studies for structural characterization of protein- protein interactions have been conducted with reagents specific for discrete amino acids. While this approach simplifies data analysis, the requirement for specific functionalities to be present at the interaction interface limits resolution. Herein, we re

APA, Harvard, Vancouver, ISO, and other styles

4

DAI, ZHENYU. "PROTEIN CROSSLINKING BY THE MAILLARD REACTION WITH ASCORBIC ACID AND GLUCOSE." Case Western Reserve University School of Graduate Studies / OhioLINK, 2007. http://rave.ohiolink.edu/etdc/view?acc_num=case1184176746.

Full text

APA, Harvard, Vancouver, ISO, and other styles

5

Müller, Fränze [Verfasser], Juri [Akademischer Betreuer] Rappsilber, Juri [Gutachter] Rappsilber, and Markus [Gutachter] Ralser. "Quantitative crosslinking mass spectrometry : development and application to protein conformation changes / Fränze Müller ; Gutachter: Juri Rappsilber, Markus Ralser ; Betreuer: Juri Rappsilber." Berlin : Technische Universität Berlin, 2020. http://d-nb.info/1213348498/34.

Full text

APA, Harvard, Vancouver, ISO, and other styles

6

Giese, Sven Hans-Joachim [Verfasser], Juri [Akademischer Betreuer] Rappsilber, Matthias [Gutachter] Selbach, and Juri [Gutachter] Rappsilber. "Computational methods and machine learning for crosslinking mass spectrometry data analysis / Sven Hans-Joachim Giese ; Gutachter: Matthias Selbach, Juri Rappsilber ; Betreuer: Juri Rappsilber." Berlin : Technische Universität Berlin, 2021. http://d-nb.info/1238140718/34.

Full text

APA, Harvard, Vancouver, ISO, and other styles

7

Ferrari, Állan Jhonathan Ramos 1991. "Caracterização estrutural da Stanniocalcina-1 por Proteômica Estrutural." [s.n.], 2015. http://repositorio.unicamp.br/jspui/handle/REPOSIP/250217.

Full text

Abstract:

Orientador: Fábio Cesar Gozzo<br>Dissertação (mestrado) - Universidade Estadual de Campinas, Instituto de Química<br>Made available in DSpace on 2018-08-27T10:34:23Z (GMT). No. of bitstreams: 1 Ferrari_AllanJhonathanRamos_M.pdf: 2074796 bytes, checksum: a9fd65df7da4d527a33e2ef562c91f73 (MD5) Previous issue date: 2015<br>Resumo: A Stanniocalcina-1 (STC1) é um hormônio glicoproteico que apresenta padrão de expressão diferencial destacado em diversas patologias, notadamente em neoplasias, mas seus aspectos funcionais e estruturais são pouco explorados até o momento. Nesse sentido, a STC1 foi es

APA, Harvard, Vancouver, ISO, and other styles

8

Garcia, del Rio Diego Fernando. "Studying protein complexes for assessing the function of ghost proteins (Ghost in the Cell)." Electronic Thesis or Diss., Université de Lille (2022-....), 2023. https://pepite-depot.univ-lille.fr/ToutIDP/EDBSL/2023/2023ULILS115.pdf.

Full text

Abstract:

Le cancer de l'ovaire (OvCa) est le cancer le plus mortel parmi les cancers féminins. Il est souvent diagnostiqué tardivement ou mal diagnostiqué, ce qui le rend difficile à traiter. Les options de traitement incluent la chirurgie ou la chimiothérapie, toutefois la résistance à la chimiothérapie est un problème majeur. Il est donc urgent de trouver de nouvelles cibles et de développer de nouvelles stratégies pour surmonter cette résistance.Dans ce contexte le protéome fantôme est une source potentiellement riche de biomarqueurs. Le protéome fantôme, ou protéome alternatif, est composé de proté

APA, Harvard, Vancouver, ISO, and other styles

9

Gafken, Philip R. "Characterization of UV-crosslinked protein-nucleic acid interfaces by Maldi MS and ESI MS/MS." Thesis, 2000. http://hdl.handle.net/1957/32805.

Full text

APA, Harvard, Vancouver, ISO, and other styles

10

Jensen, Ole Norregaard. "Characterization of photochemically cross-linked protein-nucleic acid complexes by mass spectrometry." Thesis, 1994. http://hdl.handle.net/1957/35130.

Full text

Abstract:

A novel protocol for the study of protein-nucleic acid interactions is presented and demonstrated to be feasible. The protocol combines photochemical crosslinking techniques and mass spectrometric methods into a new strategy for identifying protein domains or amino acid residues that are in close contact with nucleic acid in protein-nucleic acid complexes. Identifying nucleic acid binding domains in proteins provides a starting point for understanding structure-function relationships in protein-nucleic acid complexes. The protocol can be divided into three parts: 1) Cross linking of the protei

APA, Harvard, Vancouver, ISO, and other styles

11

Veeramachaneni, Rathna Jyothi. "Towards Structural Determination of Human α1-Glycine Receptor Allostery". 2016. http://digital.library.duq.edu/u?/etd,197204.

Full text

Abstract:

Recent advances in technology have led to the determination of numerous notable structures of membrane proteins. While they provide valuable information about the structure of membrane proteins these studies often provide static images with potentially limited dynamics, and structural determination often requires truncation of flexible regions, and often utilizes bacterial homologs given the need for stable, heterologous overexpression. In order to better understand allostery at a molecular level, state-dependent crosslinking studies coupled with multidimensional mass spectrometry (MS) were co

APA, Harvard, Vancouver, ISO, and other styles

12

Stevens, Katherine Grace. "Mass Spectrometric Methods for the Analysis of Chemically Modified Proteins." Thesis, 2021. http://hdl.handle.net/2440/131957.

Full text

Abstract:

Mass spectrometry has critical roles in analytical chemistry, biomedical research and the diagnosis and treatment of human disease. Its ability to unambiguously identify and quantify a diverse range of biomolecules, from small molecule metabolites to large intact protein complexes in complex biological matrices, has solidified this technique’s place in the clinical chemists’ laboratory. However, mass spectrometry’s wider adoption by biochemists and clinicians is hindered by the inherent volume and complexity of the data it can generate from a biological context, and the subsequent level of spe

APA, Harvard, Vancouver, ISO, and other styles

13

Weerasekera, Rasanjala Kumari. "The Development of Novel Protein Topology Mapping Strategies using Crosslinking, Cyanogen Bromide Cleavage, and Mass Spectrometry." Thesis, 2011. http://hdl.handle.net/1807/31969.

Full text

Abstract:

Advances in protein topology mapping methods are urgently needed to complement the wealth of interactome data that is presently being generated at a rapid pace. Chemical crosslinking followed by mass spectrometry (MS) has evolved over the last decade as an attractive method for protein topology and interface mapping, and holds great promise as a counterpart to modern interactome studies in the field of proteomics. Furthermore, stabilization of proteins and protein complexes with crosslinking offers many advantages over high-resolution structural mapping methods, including the ability to study

APA, Harvard, Vancouver, ISO, and other styles

14

Soderblom, Erik James. "Collision-induced dissociative crosslinking reagents and methodology for the structural analysis of proteins and protein-protein interactions using tandem mass spectrometry." 2008. http://www.lib.ncsu.edu/theses/available/etd-10202008-142218/unrestricted/etd.pdf.

Full text

APA, Harvard, Vancouver, ISO, and other styles

15

Opitz, Nadine. "Analysis of the Asc1p/RACK1 microenvironment in Saccharomyces cerevisiae using proximity-dependent Biotin Identification (BioID) and high-resolution mass spectrometry." Doctoral thesis, 2016. http://hdl.handle.net/11858/00-1735-0000-0023-3F29-D.

Full text

APA, Harvard, Vancouver, ISO, and other styles

16

Rall, Nils Arne. "A Method for the Quantitative Analysis of Protein-Protein Interactions In Vivo." Doctoral thesis, 2016. http://hdl.handle.net/11858/00-1735-0000-0028-872D-1.

Full text

APA, Harvard, Vancouver, ISO, and other styles

17

Nguyen, Quynh Vy. "Développement d'un microréacteur à base d'enzyme protéolytique réticulée avec le glutaraldéhyde pour la cartographie peptidique." Thèse, 2008. http://hdl.handle.net/1866/7830.

Full text

APA, Harvard, Vancouver, ISO, and other styles

18

Doneanu, Catalin E. "Mass spectrometric analysis of UV-crosslinked protein-nucleic acid complexes." Thesis, 2002. http://hdl.handle.net/1957/31851.

Full text

APA, Harvard, Vancouver, ISO, and other styles

19

Serpa, Jason John. "Structure of prion β-oligomers as determined by structural proteomics". Thesis, 2017. https://dspace.library.uvic.ca//handle/1828/8548.

Full text

Abstract:

The conversion of the native monomeric cellular prion protein (PrPC) into an aggregated pathological β-oligomeric (PrPβ) and an infectious form (PrPSc) is the central element in the development of prion diseases. The structure of the aggregates and the molecular mechanisms of the conformational change involved in this conversion are still unknown. My research hypothesis was that a specific structural rearrangement of normal PrPC monomers leads to the formation of new inter-subunit interaction interfaces in the prion aggregates, leading to aggregation. My approach was to use constraints obta

APA, Harvard, Vancouver, ISO, and other styles

We offer discounts on all premium plans for authors whose works are included in thematic literature selections. Contact us to get a unique promo code!