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Relevant bibliographies by topics / Crosspovidone

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Journal articles

Academic literature on the topic 'Crosspovidone'

Author: Grafiati

Published: 3 June 2025

Last updated: 1 August 2025

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Journal articles on the topic "Crosspovidone"

1

Patel, Afroza Akbar, Siraj N. Shaikh, Huzaifa Patel, Afzal Band, and Ahmed Shaoor. "Designing fabrication and evaluation of Oral fast Disintegrating tablet of Ranitidine HCL." Journal of Drug Delivery and Therapeutics 9, no. 1 (2019): 95–102. http://dx.doi.org/10.22270/jddt.v9i1.2176.

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The aim of this research work was to design develop & evaluate oral fast disintegrating tablets of Ranitidine HCL. The Orodispersible tablets of Ranitidine HCl were prepared by using direct Compression technique with a Synthetic Superdisintegrant such as Crosspovidone and a natural Superdisintegrant Fenugreek gum in different concentration. 32 factorial designs was applied to study the effect of independent variables, concentration of Crosspovidone & Fenugreek gum on dependent variables like Cumulative % Drug release and Disintegration time by using design expert software. Prepared ora

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2

Kashikar, V., N. Gandhi, and P. Dhole. "FORMULATION DEVELOPMENT AND EVALUATION OF FAST DISSOLVING TABLET OF TRIPTAN DRUG." INDIAN DRUGS 53, no. 05 (2016): 31–37. http://dx.doi.org/10.53879/id.53.05.10430.

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Almotriptan malate is a triptan class anti-migraine drug with rapid action, highest bioavailability and low side effects. Fast dissolving tablets of almotriptan malate were prepared by wet granulation technique using sodium starch glycolate, Crosscarmellose sodium and Crosspovidone (2%, 4%, and 6%), respectively, FT-IR spectroscopy and differential scanning calorimetry were used to investigate the physical characteristics of the drug. The granules were examined for angle of repose, bulk density, tapped density, index and Hausner’s ratio. Developed tablets were evaluated for hardness, drug cont

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3

R. Venkatarao, K. Vinod Kumar, and B.Thangabalan. "Development and Characterization of Linagliptin Oral Disintegrating Tablets." International Journal of Allied Medical Sciences and Clinical Research 12, no. 1 (2024): 4–12. http://dx.doi.org/10.61096/ijamscr.v12.iss1.2024.4-12.

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Linagliptin is an anti-diabetic drug used for the treatment of type 2 diabetes, it is belongs to the class of dpp-4 inhibitor. It has long half-life of about 8.6-23.9 hours and hence to achieve immediate therapeutic action it needs immediate release tablet formulation. Among the various techniques using superdisintegrants is a simple approach to formulate immediate release tablets. It undergoes an extensive hepatic first pass metabolism leads to low oral bioavailability (30%). ODT can overcome this problem through improving its bioavailability with an immediate drug release. In the present wor

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4

Arora, V., S. Kumar, P. B. Mishra, and N. Vashisht. "FORMULATION AND EVALUATION OF MOUTH DISSOLVING TABLETS OF RANITIDINE HYDROCHLORIDE." INDIAN DRUGS 52, no. 09 (2015): 13–20. http://dx.doi.org/10.53879/id.52.09.p0013.

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In present research work, taste masked Mouth Dissolving Tablets (MDTs) of Ranitidine Hydrochloride were designed with a view to enhance the patient compliance and provide a quick onset of action. Taste masking of the drug was done by formation of complex with β cyclodextrin. Tablets were prepared by direct compression, using superdisintegrants like crosscarmellose sodium and crosspovidone in different proportion and evaluated for the pre-compression parameters such as bulk density, compressibility, angle of repose etc. In view of the better taste palatability of such a bitter API, taste maskin

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5

Polishetty, Saipriya* Mariyam Suryaprakash Reddy SK. Irfan Khan Afshan Urooj Dr. Y. Krishna Reddy Dr.K. N. V. Rao Dr. K. Rajeswar Dutt. "FORMULATION, OPTIMIZATION AND EVALUATION OF ESLICARBAZEPINE ACETATE." INDO AMERICAN JOURNAL OF PHARMACEUTICAL SCIENCES 05, no. 03 (2018): 1688–93. https://doi.org/10.5281/zenodo.1209355.

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The present study aims at developing an Eslicarbazepine fast dissolving tablet formulation for the effctive treatment of Epilepsy. To provide the patient with the most convenient mode of administration, FDT’s will dissolve quickly. A Eslicarbazepine is absorbed to atleast 90% from the gut, independently of food intake. It is quickly metabolized to esclicarbazepine. So the present work was aimed at formulating fast dissolving tablet for Eslicarbazepine, total 6 formulations were developed by using synthetic superdisintigrants like cross caramellose sodium, Crosspovidone, sodium starch gly

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6

Nestorovska-Gjosevska, Biljana Nestorovska-Gjosevska, Marija Glavas-Dodov, and Katerina Goracinova. "Orally disintegrating tablet: formulation design and optimisation using Response Surface Methodology." Macedonian Pharmaceutical Bulletin 51 (2005): 15–22. http://dx.doi.org/10.33320/maced.pharm.bull.2005.51.003.

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The objective of this study was to develop diazepam orally disintegrating tablets and to optimize tablets characteristics using response surface methodology (RSM). Tablets were prepared by direct compression of mixture containing mannitol, copovidone, crosspovidone flavor and lubricant. A full factorial design for 2 factors at 3 levels each was applied to investigate the influence of 2 formulation variables on the mechanical strength/hardness, the percent of friability, disintegration time and dissolution of the poorly soluble active ingredient. The amounts of copovidone and crosspovidone were

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7

Reddy, Dr D. RamaBrahma, Dr Ch N. V. S. Mastan Rao, K. John Abhi K. John Abhi, et al. "An Overview on Immediate Drug Release of Pravastatin Drug." International Journal of Pharmaceutical Research and Applications 10, no. 1 (2025): 847–50. https://doi.org/10.35629/4494-1001847850.

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The objective of this research was to formulate fast dissolving tablets of Pravastatin sodium that disintegrate in the oral cavity upon contact with saliva and there by improve therapeutic efficacy. Pravastatin sodium is used for the treatment of myocardial infarction. Fast dissolving tablets of pravastatin sodium were prepared by direct compression method using three different superdisintegrants-Sodium starch glycollate, Croscarmellose sodium and Crosspovidone (2%, 4% and 6%) and three different diluents (mannitol and spray dried lactose) in different concentrations. Eighteen formulations wer

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8

Mohammed Abdelrahman1,2*, Mohamed A. M. Elhassan1, Alaa Alsadig Alzain1, et al. "Formulation and Evaluation of Quinine sulfate Dispersible Tablets with Emphasis on Taste Masking using Cyclodextrin." Omdurman Journal of Pharmaceutical Sciences 2, no. 3 (2022): 275–85. http://dx.doi.org/10.52981/ojps.v2i3.2875.

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Dispersible tablets (DTs), also termed quick dissolving, fast melting, fast dissolving, fast disintegrating and rapid dissolving tablets, are uncoated or film-coated tablets intended to be dispersed in water before administration giving a homogeneous dispersion. Conventional quinine tablets have bitter taste when broken or dispersed to allow administration for children. Cyclodextrins (CDs) are cyclic oligosaccharides whose structural feature gives a hydrophobic interior and a hydrophilic exterior are widely used to increase the solubility of poorly soluble drugs. Recent studies showed that CDs

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9

Raju, Bodhle Priyanka, and Satish V. Shirolkar. "Formulation and Evaluation of Teneligliptine Pellet." International Journal of Drug Delivery Technology 9, no. 01 (2019): 51–57. http://dx.doi.org/10.25258/ijddt.9.1.9.

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The present study is an attempt to formulate and evaluate Teneligliptin hydrobromide hydrate pellets. Teneligliptin is a potent, selective DPP-4 inhibitor, which is believed to exert its actions in diabetes mellitus patients. Teneligliptin increases insulin release and decreases glucagon levels in the circulation in a glucose dependent manner. The Teneligliptin pellets were prepared by using blend of MCC, Lactose, Crospovidone and PVP K-30. Pellet formulation was optimized for formulation parameters (concentration of Crosspovidone and PVP K-30) using 32 factorial design. FTIR studies showed ab

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10

Mahata, Jaydip, Jeevan Patel, Ramakant Sharma, and Rakesh Patel. "Formulation and Evaluation of Bilayer Tablet of Saxagliptin." International Journal of Pharmaceutical Sciences and Medicine 7, no. 5 (2022): 72–86. http://dx.doi.org/10.47760/ijpsm.2022.v07i05.007.

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In the present study Saxagliptin 60mg tablets have been formulated and developed using direct compression and dry granulation technique, to provide a safe, highly effective method for treating congestive heart failure, edema and kidney disorder, while reducing undesirable adverse effects. Pre and post formulation parameters were studied for the formulated batches. The result of all the physical and in-vitro dissolution data concluded that bilayer tablet (I3,S9) was the most promising formulation. The trial conducted with the consecutive three batches for immediate release and sustained release

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