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1

Aderinola, Musefiu, Bokolo Abovie, Festus Okosi, Igoniderigha Daniel, and G. F. Odubo. "Analysis of Different Ways of Crosstalk Measurement in GSM Network." International Journal of Reconfigurable and Embedded Systems (IJRES) 5, no. 2 (2016): 106. http://dx.doi.org/10.11591/ijres.v5.i2.pp106-110.

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<p>Crosstalk is one of the problems that affect the performance operation of global system mobile (GSM) network. Among the effect of crosstalk are call mute, call drop, wire propagation delay, dynamic power dissipation etc. Crosstalk is an undesirable signal arising due to the coupling capacitances between adjacent interconnecting wires and measured in decibel. In this paper some literature were reviewed and different ways of measuring crosstalk such as Near end croosstalk (NEXT), far end crosstalk (FEXT), Power sum crosstalk (PSNEXT) and alien crosstalk (AXT) were analyzed. </p>
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Lin, Ding-Bing, Ariana Purnomo, and Chung-Pin Huang. "Crosstalk Reduction on Delay Line with Rectangular-Patches (RPs) Design." Applied Computational Electromagnetics Society 36, no. 1 (2021): 10–19. http://dx.doi.org/10.47037/2020.aces.j.360102.

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In this paper, a novel helix delay line with RPs structures is proposed to investigate the performance of crosstalk reduction. In the past, conventional delay lines consist of equal-length parallel unit lines which are closely packed to minimize the fabricated cost and routing area. All spacing between the adjacent parallel unit lines of delay lines should be smaller. When the operating signal frequency ups to the GHz level, the electromagnetic noise has become a dominant issue coupling from adjacent lines. It is called as a crosstalk source. The crosstalk may affect system-level timing. Besid
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3

Song, Kyunghwan, Jongwook Kim, Hyunwoong Kim, et al. "Modeling, Verification and Signal Integrity Analysis of High-Speed Signaling Channel with Tabbed Routing in High Performance Computing Server Board." Electronics 10, no. 13 (2021): 1590. http://dx.doi.org/10.3390/electronics10131590.

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It is necessary to reduce the crosstalk noise in high-speed signaling channels. In the channel routing area, the tabbed routing pattern is used to mitigate far-end crosstalk (FEXT), and the electrical length is controlled with a time domain reflectometer (TDR) and time domain transmission (TDT). However, unlike traditional channels having uniform width and space, the width and space of tabbed routing changes by segment, and the capacitance and inductance values of tabbed routing also change. In this paper, we propose a tabbed routing equivalent circuit modeling method using the segmentation ap
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Lee, Won-Jong, Dong-Gyu Kim, and Woo-Su Kim. "Enhancing the Electromagnetic Interference Performance of Vehicle Connectors Using Wave-Shaped Techniques." Korea Industrial Technology Convergence Society 28, no. 4 (2023): 189–95. http://dx.doi.org/10.29279/jitr.2023.28.4.189.

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This study shows the improvement in sufficient crosstalk and electromagnetic interference (EMI) performance by designing the terminal structure of a wave-shaped connector. In addition, impedance was improved without reducing the size of the terminal width of the connector. The operating range of the designed connector extended up to 6 GHz, providing 15-20 dB improvement in far-end crosstalk (FEXT) performance and 10-35 dB improvement in near-end crosstalk (NEXT) compared with traditional straight terminal methods.
 The EMI performance also improved by approximately 20 μV/m when applying t
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5

Hussein, Ahmed Ali. "Using rectangular trace to reduce the crosstalk of the coupled microstrip lines." International Journal of Engineering & Technology 5, no. 1 (2015): 7. http://dx.doi.org/10.14419/ijet.v5i1.4771.

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New electronic products must have high-speed, small size and lower voltages supply. With such layout, signal integrity (SI) becomes an actual important issue because sensitive equipment is affected on electromagnetic interference (EMI). Crosstalk is a major factor in signal integrity (SI) of printed circuit boards (PCBs). Crosstalk noise is usually represented in terms of Near-End crosstalk (NEXT) and Far-End crosstalk (FEXT). Crosstalk is a common problem that degrades circuit performance. To reduce this problem, via hole-fences connected by guard trace between double microstrip lines are use
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Singh, Saumya. "Analysis of Signal Processing for Gigabit Rate Wireline Communication." International Journal for Research in Applied Science and Engineering Technology 9, no. VI (2021): 1181–84. http://dx.doi.org/10.22214/ijraset.2021.35165.

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In this paper we mainly focus on achieving higher speed data which is about 1Gb/s over short copper loops using G.Fast technology. The use of TDD and higher bandwidth are two key features in G.Fast. Short twisted pair cable models are used to operate at relatively wider bandwidth. At higher frequencies, the problem of FEXT crosstalk becomes dominant. So to overcome these issues we are using different crosstalk cancellation techniques using various cables which provide different data rates at different frequencies and distances. Performance analysis of various crosstalk cancelation techniques h
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7

Gao, Yin Han, Tian Hao Wang, Kai Yu Yang, Jun Dong Zhang, Jin Yu, and Liu Yang. "The Analysis of Automotive Wiring Harness Dynamic Crosstalk." Applied Mechanics and Materials 543-547 (March 2014): 817–20. http://dx.doi.org/10.4028/www.scientific.net/amm.543-547.817.

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Since the installation and strapping of the harness, and the vehicle motion state of the automotive is different. The crosstalk automotive wire harness is not a fixed value, but a certain dynamic range in the actual situation. Through the analysis of the factors of influence cable crosstalk can draw a conclusion that the cable relative position and disturbed line termination impedance is a major factor in the production of dynamic change. We analyze the dynamic range of crosstalk of 14 core wire harness model by using a statistical method, as a result of the change of the relative position of
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8

Zafaruddin, S. M., Shankar Prakriya, and Surendra Prasad. "Iterative Receiver Based on SAGE Algorithm for Crosstalk Cancellation in Upstream Vectored VDSL." ISRN Communications and Networking 2011 (June 30, 2011): 1–15. http://dx.doi.org/10.5402/2011/586574.

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We propose the use of an iterative receiver based on the Space Alternating Generalized Expectation maximization (SAGE) algorithm for crosstalk cancellation in upstream vectored VDSL. In the absence of alien crosstalk, we show that when initialized with the frequency-domain equalizer (FEQ) output, the far-end crosstalk (FEXT) can be cancelled with no more real-time complexity than the existing linear receivers. In addition, the suggested approach does not require offline computation of the channel inverse and thus reduces the receiver complexity. In the presence of alien crosstalk, there is a s
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9

V, Yokesh. "On the Design of a Stepped Mixed Signal Transmission Line with Defected Microstrip Structure for High-Frequency PCB Traces." JOURNAL OF HIGH-FREQUENCY COMMUNICATION TECHNOLOGIES 2, no. 01 (2024): 120–29. http://dx.doi.org/10.58399/rzrq1838.

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The paper addresses the challenge of crosstalk in neighboring paths on PCBs, emphasizing its growing importance with the advancement of electronic circuits in terms of speed and frequency. The proposed solution involves the introduction of a novel W-shaped Defected Microstrip Structure (DMS) on a step-shaped coupled transmission lines to mitigate near-end crosstalk (NEXT) and far-end crosstalk (FEXT) using mixed signal input. A novel W-shaped defective microstrip structure (DMS) that is etched on step-shaped coupled transmission lines. The proposed technique focuses on minimizing the electroma
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10

Gu, Moses, Suin Chae, Seonwoo Kim, et al. "High-Performance EMI Shielding Film Based on Low-Dk Polyimide and Trimodal Ag Ink for High-Speed Signal Integrity Enhancement." Micro 5, no. 2 (2025): 26. https://doi.org/10.3390/micro5020026.

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Electromagnetic interference (EMI) shielding is critical for maintaining signal integrity in high-speed electronic packaging. However, conventional shielding approaches face limitations in process complexity and spatial efficiency. In this study, an EMI shielding film based on trimodal silver (Ag) ink and low-dielectric polyimide (PI) resin was developed and comprehensively evaluated. The fabricated film exhibited an average shielding effectiveness (SE) of −99.7 dB in the 6–18 GHz frequency range and demonstrated a 50% increase in electrical conductivity after lamination (from 0.752 × 105 S/m
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Zhan, Haibing, Xiaochun Li, Changsheng Sun, and Ken Ning. "A Low-Loss and High-Bandwidth Horizontally Polarized Transition Between Rectangular Polymer Dielectric Waveguide and Microstrip Line for Array Application." Electronics 14, no. 12 (2025): 2345. https://doi.org/10.3390/electronics14122345.

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To achieve interconnects of rectangular polymer dielectric waveguides (PDWs) at the W-band, this paper presents a novel low-loss and high-bandwidth horizontally polarized transition between a rectangular PDW and a microstrip line (ML), which can achieve a rectangular PDW array. The proposed structure consists of a patch, a bent ridge waveguide, a tapered ridge waveguide, a dielectric-filled waveguide, and a tapered horn. An equivalent circuit model is established for synthesis design, and the transition is manufactured utilizing printed circuit board (PCB) and computerized numerical control (C
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Illiano, Ludovica, Xiaokang Liu, Xinglong Wu, Flavia Grassi, and Sergio Amedeo Pignari. "Signal Order Optimization of Interconnects Enabling High Electromagnetic Compatibility Performance in Modern Electrical Systems." Energies 17, no. 11 (2024): 2786. http://dx.doi.org/10.3390/en17112786.

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Flexible flat cables (FFCs) are a typical form of interconnect in modern electrical and electronic systems that facilitate signal transmission between components while minimizing harness volume. FFCs offer a practical connectivity solution in energy management applications, where sensors and displays are essential for monitoring power consumption and performing advanced digital control. In FFCs, signal lines run parallel to each other, and the proximity between lines can cause interference among adjacent signals. Therefore, the arrangement of signals along different lines can significantly inf
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Fu, Ting, and Xingchen Dong. "Abstract 3442: FXR mediates macrophage intrinsic responses to suppress colon cancer progression." Cancer Research 83, no. 7_Supplement (2023): 3442. http://dx.doi.org/10.1158/1538-7445.am2023-3442.

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Abstract Bile acids (BAs) affect the intestinal environment by ensuring barrier integrity, regulating epithelium turnover, maintaining microbiota balance, and modulating the immune system. As a master regulator of BAs homeostasis and innate immunity, Farnesoid X Receptor (FXR), is severely compromised in inflammatory bowel disease (IBD) and colitis-associated colorectal carcinoma (CAC) patients. At the front line, gut macrophages react to the microbiota and metabolites that breach the epithelium. We aim to study the role of the BAs-FXR axis in macrophages. To dissect how inflammation drives tu
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14

Faritcan Siallagan, Timbo. "Garbage Disposal Information System Using Internet of Things." International Journal of Management Science and Information Technology 3, no. 1 (2023): 54–60. http://dx.doi.org/10.35870/ijmsit.v3i1.923.

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The waste management carried out by the Puri Panji Kencana Residential and Buana Grand Subang Housing Communities, West Java, is related to the community's perception of waste and the condition of the area where they live. Therefore, this study aims to determine the public's perception of waste, the waste management system, and the public's perception of the effectiveness of waste management in areas with different topography. This study used a survey method with data collection techniques in the form of distributing questionnaires to the respondents. The sampling technique used in this study
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15

Harachi, Mio, Kenta Masui, Yukinori Okamura, Ryota Tsukui, Paul Mischel, and Noriyuki Shibata. "mTOR Complexes as a Nutrient Sensor for Driving Cancer Progression." International Journal of Molecular Sciences 19, no. 10 (2018): 3267. http://dx.doi.org/10.3390/ijms19103267.

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Recent advancement in the field of molecular cancer research has clearly revealed that abnormality of oncogenes or tumor suppressor genes causes tumor progression thorough the promotion of intracellular metabolism. Metabolic reprogramming is one of the strategies for cancer cells to ensure their survival by enabling cancer cells to obtain the macromolecular precursors and energy needed for the rapid growth. However, an orchestration of appropriate metabolic reactions for the cancer cell survival requires the precise mechanism to sense and harness the nutrient in the microenvironment. Mammalian
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16

Van Der Hofstadt, Marc, Anna Cardinal, Morgane Lepeltier, et al. "Assessment of salivary microRNA by RT-qPCR: Facing challenges in data interpretation for clinical diagnosis." PLOS ONE 19, no. 12 (2024): e0314733. https://doi.org/10.1371/journal.pone.0314733.

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Salivary microRNAs (miRNAs) have been recently revealed as the next generation of non-invasive biomarkers for the diagnostics of diverse diseases. However, their short and highly homologous sequences make their quantification by RT-qPCR technique highly heterogeneous and study dependent, thus limiting their implementation for clinical applications. In this study, we evaluated the use of a widely used commercial RT-qPCR kit for quantification of salivary miRNAs for clinical diagnostics. Saliva from ten healthy volunteers were sampled four times within a three month time course and submitted for
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17

Gugu, Mitilda, Shubhra Acharya, Dogukan Pira, et al. "IMMUnity Unveiled: A Translational NETwork for tackling PARKinson's Disease – IMMUPARKNET." Open Research Europe 4 (June 19, 2024): 119. http://dx.doi.org/10.12688/openreseurope.17547.1.

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Parkinson’s disease (PD) affects more than one million people in the EU. It currently has no definitive cure, meaning that patients rely only on symptomatic treatments, which themselves are burdened by side effects. The need for advancements in both knowledge and available treatments is thus strongly felt by patients, caregivers, and health operators. This unmet need sparked the idea of orchestrating a collaborative effort via a common network – IMMUPARKNET (The role of IMMUnity in tackling PARKinson’s disease through a Translational NETwork). The IMMUPARKNET COST Action focuses on challenges
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18

Gugu, Mitilda, Shubhra Acharya, Dogukan Pira, et al. "IMMUnity Unveiled: A Translational NETwork for tackling PARKinson's Disease – IMMUPARKNET." Open Research Europe 4 (January 23, 2025): 119. https://doi.org/10.12688/openreseurope.17547.2.

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Parkinson’s disease (PD) affects more than one million people in the EU. It currently has no definitive cure, meaning that patients rely only on symptomatic treatments, which themselves are burdened by side effects. The need for advancements in both knowledge and available treatments is thus strongly felt by patients, caregivers, and health operators. This unmet need sparked the idea of orchestrating a collaborative effort via a common network – IMMUPARKNET (The role of IMMUnity in tackling PARKinson’s disease through a Translational NETwork). The IMMUPARKNET COST Action focuses on challenges
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19

Bria, Melchior, Ludfi Djakfar, and Achmad Wicaksono. "EMPLOYEE COMMUTING IN NEW NORMAL: AN ANALYSIS BASED ON HOUSEHOLD CHARACTERISTICS AND PERCEPTION ON HEALTH PROTOCOLS." Journal of Southwest Jiaotong University 56, no. 6 (2021): 58–72. http://dx.doi.org/10.35741/issn.0258-2724.56.6.6.

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This article describes a new approach in understanding the behavior in selecting modes for commuting to work based on the correlation between household factors and perceptions of health protocols in public transportation during the new normal. Data from 430 respondents living in Jakarta were collected, including household characteristics (age, number of family members, income, vehicle ownership, type of work), perceptions of health protocol services in public transportation, and use of transportation modes. Cross-tabulation (crosstab) was used to describe the relationship between variables. Re
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Rosdiana, Rahma, Ersy Ervina, and Tito Pandu Raharjo. "Studi Komparasi Pengalaman Menginap Tamu pada Hotel Kabin Area Perkotaan dan Kawasan Wisata Kota Bandung." Al-Kharaj: Jurnal Ekonomi, Keuangan & Bisnis Syariah 6, no. 4 (2024): 4217–28. http://dx.doi.org/10.47467/alkharaj.v6i4.929.

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Cabin and low budget hotels are in great demand today, both in urban areas and in tourist areas. Although much in demand, until now there has been no research that measures how the experience of staying in urban areas and tourist areas compares. This study aims to analyze the guest's stay experience at the cabin hotel by comparing the two objects so that it can be used as an evaluation for the cabin hotel management to further improve service quality in providing a good stay experience. The approach used in this study is descriptive quantitative with cross-tabulation data analysis (Crosstab) a
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21

Hajji, Apif M., Nasta Natasya, and Viola Malta. "User’s Perception of Indoor Air Quality (IAQ) in Tall Office Buildings as the Cause of Symptoms of Sick Building Syndrome." E3S Web of Conferences 445 (2023): 01010. http://dx.doi.org/10.1051/e3sconf/202344501010.

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The user’s assessment or perception of indoor air quality (IAQ) refers to an individual’s subjective assessment or perception of the quality of the air they breathe inside a particular building or space. This assessment or perception is very individual and can vary from one individual to another. This study aims to determine the IAQ felt by users of the Rectorate Building, State University of Malang, and its effect on Sick Building Syndrome (SBS) symptoms. This research is included in the quantitative research with the study population being all employees at the building, which has 215 people.
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Setiawan, Nico, and Priyendiswara Agustina Bella. "STUDI DAMPAK OPERASIONAL ZONA INDUSTRI KE HUNIAN SEKITAR (OBJEK STUDI KORIDOR JL. DAAN MOGOT, TANGERANG)." Jurnal Sains, Teknologi, Urban, Perancangan, Arsitektur (Stupa) 4, no. 2 (2023): 2991–3002. http://dx.doi.org/10.24912/stupa.v4i2.22460.

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Study of Operational Impact of Industrial Zones to Surrounding Residential Areas (Object of Corridor Study on Jl. Daan Mogot, Tangerang). Within the boundaries of the object of study located along Jl. Daan Mogot Km 24 – Km 23, Tangerang, there is a discrepancy in the type of land use with the Plan set out in the Tangerang City RTRW 2032 with its existing condition. With a total of 32 industries operating in various commodities, the dominant level of disturbance relatively high, so security of the people living in the vicinity becomes more risky. By using the method of analyzing the potential a
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23

V., Yokesh, Gulam Nabi Alsath, and Malathi Kanagasabai. "Defected microstrip structure-based near-end and far-end crosstalk mitigation in high-speed PCBs for mixed signals." Microelectronics International, December 7, 2022. http://dx.doi.org/10.1108/mi-05-2022-0089.

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Purpose The design, fabrication and experimental validation of defected microstrip structure (DMS) are proposed to address the problem of near-end crosstalk (NEXT) and far-end crosstalk (FEXT) between the microstrip transmission lines in a printed circuit board. Design/methodology/approach The proposed DMS evolved with the combination of spur line (L-shaped DMS) and U-shaped DMS topologies. This technique reduces the strength of electromagnetic coupling and suppresses crosstalk by optimizing the capacitive and inductive coupling ratio between the linked microstrip lines. The practical inductan
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24

V., Yokesh, Gulam Nabi Alsath Mohammed, and Malathi Kanagasabai. "Crosstalk reduction using novel cross-shaped resonators with via fence in high-frequency transmission lines." Circuit World, October 27, 2021. http://dx.doi.org/10.1108/cw-04-2021-0099.

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Purpose The purpose of this paper is to design a suitable guard trace to reduce the electromagentic interference between two closely spaced high frequency transmission lines. A novel cross-shaped resonator combined via fence is passed down to alleviate far-end and near-end crosstalk (NEXT) in tightly coupled high-speed transmission lines. The distance between the adjacent transmission lines is increased stepwise as a function of trace width. Design/methodology/approach A rectangular-shaped resonator via fence is connected by a guard trace has been proposed to overcome the coupling between the
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Venkatesh, Yokesh, Gulam Nabi Alsath Mohammed, and Malathi Kanagasabai. "Periodically Loaded Transmission Lines for Digital Signal Transmission in Homogeneous Media: Design and Analysis." Microwave and Optical Technology Letters 67, no. 6 (2025). https://doi.org/10.1002/mop.70267.

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ABSTRACTThis paper focuses on the design, fabrication and analysis of a periodically loaded transmission line (PLTL) within a homogenous medium. The proposed method aims to mitigate near‐end crosstalk (NEXT) and far‐end crosstalk (FEXT) improve the overall transmission performance for digital signal data transmission over a frequency range of 1 to 14 GHz. The periodic loading is designed to optimize the coupling ratios between capacitive and inductive components, leading to a more balanced and efficient microstrip transmission line. Unlike traditional microstrip configurations, the PLTLs in a
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Zhang, Wu, Yongji Wu, Jiafei Ding, Yang Zhao, and Mingyuan He. "A New Method for Twisted Wire Crosstalk Estimation Based on GA-BP Neural Network Algorithm." Applied Computational Electromagnetics Society Journal (ACES), December 14, 2022. http://dx.doi.org/10.13052/2022.aces.j.370601.

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Based on the research of genetic algorithm (GA) to optimize the BP neural network algorithm, this paper proposes a method for predicting twisted wire crosstalk based on the algorithm. Firstly, the equivalent circuit model of a multi-conductor transmission line is established, combined with the method of similarity transformation, the second-order differential transmission line equations are decoupled into n groups of independent two-conductor transmission line equations, and the crosstalk is finally solved. Then the mathematical model of the twisted wire is established and its structural chara
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Jeong, Yong-Un, Sungphil Choi, Suhwan Kim, and Joo-Hyung Chae. "Single-Ended Receiver-Side Crosstalk Cancellation With Independent Gain and Timing Control for Minimum Residual FEXT." IEEE Transactions on Circuits and Systems I: Regular Papers, 2023, 1–11. http://dx.doi.org/10.1109/tcsi.2023.3290623.

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"Multi-Pair Cable Measurements for 5G Indoor Service Provisioning." Journal of Networking and Network Applications 1, no. 1 (2021): 28–39. http://dx.doi.org/10.33969/j-nana.2021.010104.

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This paper considers the 5G new radio (NR) indoor service provisioning scenario where the CPRI link terminates at remote radio unit (RRU) in the building and multi-pair cable, i.e. CAT-5, is used to provide connectivity between distributed antenna unit (DAU) and RRU. The paper focuses on the de-tailed methodology for multi-pair copper channel measurement including measurement equipment specifications, their respective settings, measurement parameters i.e. characteristics impedance, insertion loss (IL), far-end-crosstalk (FEXT) and near-end-crosstalk (NEXT). The measurements include the cables
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Schlich, R., H. Sell, and J. Eckel. "VEGF und CD36 als Schlüsselmoleküle im Crosstalk zwischen perivaskulärem Fett und humanen glatten Muskelzellen." Diabetologie und Stoffwechsel 5, S 01 (2010). http://dx.doi.org/10.1055/s-0030-1254014.

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Hossain, Sehtab, Md Arif Iqbal, Prerana Samant, Mahbube K. Siddiki, and Mostafizur Rahman. "More Than a Device: Function Implementation in a Multi-Gate Junctionless FET Structure." Journal of Electronics and Electrical Engineering, January 4, 2023, 1. http://dx.doi.org/10.37256/jeee.2120231848.

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The miniaturization of the transistor sizes to keep up with Moore's Law in Integrated Circuits (ICs) is rapidly approaching the physical limits. To push the horizons of Moore's Law, among the various approaches available in the literature, single device-based computing shows promise by achieving more functionality in a smaller footprint. However, a single device-based computing approach either mainly embeds only the primitive logic hence inefficient in performance, or requires exotic devices like spin logic devices, and memristor which involve non-conventional costly manufacturing steps. Previ
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Sell, H., J. Laurencikiene, A. Taube, et al. "Chemerin als neues Adipokin im Crosstalk zwischen Fett und Muskel: Regulation der Chemerinsekretion aus Adipozyten und Induktion von Insulinresistenz in humanen Skelettmuskelzellen." Diabetologie und Stoffwechsel 4, S 01 (2009). http://dx.doi.org/10.1055/s-0029-1221994.

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Cutolo, Antonello, Angelo Rosario Carotenuto, Maria Alessandra Cutolo, et al. "Ultrasound waves in tumors via needle irradiation for precise medicine." Scientific Reports 12, no. 1 (2022). http://dx.doi.org/10.1038/s41598-022-10407-5.

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AbstractGrounded in the interdisciplinary crosstalk among physics and biological sciences, precision medicine-based diagnosis and treatment strategies have recently gained great attention for the actual applicability of new engineered approaches in many medical fields, particularly in oncology. Within this framework, the use of ultrasounds employed to attack cancer cells in tumors to induce possible mechanical damage at different scales has received growing attention from scholars and scientists worldwide. With these considerations in mind, on the basis of ad hoc elastodynamic solutions and nu
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He, Shasha, Jie Yu, Penghui Cheng, et al. "Differential Optical Imaging of Antigen Presentation Machinery Using Molecular Optical Reporters." Advanced Materials, May 15, 2025. https://doi.org/10.1002/adma.202420393.

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AbstractDetection of antigen presentation is central to understanding immunological processes and developing therapeutics for cancer, infectious diseases, and allergies. However, methods with the ability to dynamically and noninvasively distinguish between major histocompatibility complex class I (MHC‐I) and MHC‐II antigen presentations remain lacking. Herein, we develop activatable molecular optical reporters (MORs) for real‐time differential imaging of antigen presentations in lymph nodes (LNs). These MORs are engineered to passively target LNs and activated through proteolytic cleavage by k
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Évora, Artemizia, Gonçalo Garcia, Ana Rubi, et al. "Exosomes enriched with miR-124-3p show therapeutic potential in a new microfluidic triculture model that recapitulates neuron–glia crosstalk in Alzheimer’s disease." Frontiers in Pharmacology 16 (March 12, 2025). https://doi.org/10.3389/fphar.2025.1474012.

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BackgroundAlzheimer’s disease (AD), a complex neurodegenerative disease associated with ageing, is the leading cause of dementia. Few people with early AD are eligible for the novel Food and Drug Administration (FDA)-approved drug treatments. Accordingly, new tools and early diagnosis markers are required to predict subtypes, individual stages, and the most suitable personalized treatment. We previously demonstrated that the regulation of microRNA (miR)-124 is crucial for proper neuronal function and microglia reshaping in human AD cell models.ObjectiveThe aim of this study was to develop an e
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Gugu, Mitilda, Shubhra Acharya, Dogukan Pira, et al. "IMMUnity Unveiled: A Translational NETwork for tackling PARKinson's Disease – IMMUPARKNET." Open Research Europe, June 19, 2024. https://doi.org/10.12688/openreseurope.17547.1.

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Parkinson's disease (PD) affects more than one million people in the EU. It currently has no definitive cure, meaning that patients rely only on symptomatic treatments, which themselves are burdened by side effects. The need for advancements in both knowledge and available treatments is thus strongly felt by patients, caregivers, and health operators. This unmet need sparked the idea of orchestrating a collaborative effort via a common network – IMMUPARKNET (The role of IMMUnity in tackling PARKinson's disease through a Translational NETwork).The IMMUPARKNET COST Action focuses on challenges i
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Gugu, Mitilda, Shubhra Acharya, Dogukan Pira, et al. "IMMUnity Unveiled: A Translational NETwork for tackling PARKinson's Disease – IMMUPARKNET." Open Research Europe, January 23, 2025. https://doi.org/10.12688/openreseurope.17547.2.

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Parkinson's disease (PD) affects more than one million people in the EU. It currently has no definitive cure, meaning that patients rely only on symptomatic treatments, which themselves are burdened by side effects. The need for advancements in both knowledge and available treatments is thus strongly felt by patients, caregivers, and health operators. This unmet need sparked the idea of orchestrating a collaborative effort via a common network – IMMUPARKNET (The role of IMMUnity in tackling PARKinson's disease through a Translational NETwork).The IMMUPARKNET COST Action focuses on challenges i
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Bjerre, Rie Dybboe, Jacob Bak Holm, Albert Palleja, Julie Sølberg, Lone Skov, and Jeanne Duus Johansen. "Skin dysbiosis in the microbiome in atopic dermatitis is site-specific and involves bacteria, fungus and virus." BMC Microbiology 21, no. 1 (2021). http://dx.doi.org/10.1186/s12866-021-02302-2.

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Abstract Background Microbial dysbiosis with increased Staphylococcus aureus (S. aureus) colonization on the skin is a hallmark of atopic dermatitis (AD), however most microbiome studies focus on bacteria in the flexures and the microbial composition at other body sites have not been studied systematically. Objectives The aim of the study is to characterize the skin microbiome, including bacteria, fungi and virus, at different body sites in relation to AD, lesional state, and S. aureus colonization, and to test whether the nares could be a reservoir for S. aureus strain colonization. Methods U
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Pratiwi, Putu Yudari, and I. Gusti Ayu Putu Wulan Budisetyani. "Emosi dan Penggunaan Warna Dominan Pada Kegiatan Mewarnai Anak Usia Dini." Jurnal Psikologi Udayana 1, no. 1 (2013). http://dx.doi.org/10.24843/jpu.2013.v01.i01.p16.

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This study aims to determine the emotion influence towards use of the dominant color on early childhood coloring activities and also see the influence of positive and negative emotions toward the dominant color that used. Emotions are a condition that involves physiological, psychological, and feelings to act, because of the stimulus received by the senses, will be response, and processed. Emotions can be divided into positive emotions consist of happiness, excitement, also surprise and negative emotions consist of anger, sadness, fear, and disgust. Colors can manifest emotions that felt by so
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Courville, Katheryn A., and Robert Dickson. "Abstract T MP106: Nursing Acceptance of a Novel Care Coordination Application to Reduce Time to Thrombolysis in Patients with Acute Ischemic Stroke: A Pilot Study." Stroke 46, suppl_1 (2015). http://dx.doi.org/10.1161/str.46.suppl_1.tmp106.

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Background: STOP STROKE© is a novel medical application (app) developed to improve care coordination in acute ischemic stroke and was previously demonstrated to improve door to thrombolytic times. The app captures stroke benchmarking data in real time for quality assurance/improvement. Current literature reports that successful adoption of new health care technologies is not decided by hospital administration, but determined on the work floor. Purpose: We seek to determine the feasibility of an instrument used to measure end users’ intent to use, perceived usefulness, and perceived ease of use
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Middlemost, Renee. "The Simpsons Do the Nineties." M/C Journal 21, no. 5 (2018). http://dx.doi.org/10.5204/mcj.1468.

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Now in its thirtieth season, in 2018, The Simpsons is a popular culture phenomenon. The series is known as much for its social commentary as its humour and celebrity appearances. Nonetheless, The Simpsons’ ratings have declined steadily since the early 2000s, and fans have grown more vocal in their calls for the program’s end. This article provides a case study of episode “That 90s Show” (S19, E11) as a flashpoint that exemplifies fan desires for the series’ conclusion. This episode is one of the most contentious in the program’s history, with online outrage at the retconning of canon and both
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