Academic literature on the topic 'Crotonic acid'

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Journal articles on the topic "Crotonic acid"

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Lương, Thị Thanh, Phương Linh Trần, Thị Ngọc Trang Vũ та ін. "CẢI TIẾN TỔNG HỢP ACID (E)-4-(PIPERIDIN-1-YL) BUT-2-ENOIC HYDROCLORID LÀM CHẤT TRUNG GIAN QUAN TRỌNG TRONG ĐIỀU CHẾ THUỐC ĐIỀU TRỊ UNG THƯ PHỔI DACOMITINIB". Tạp chí Y Dược học Cần Thơ, № 84 (25 лютого 2025): 122–28. https://doi.org/10.58490/ctump.2025i84.3295.

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Đặt vấn đề: Dacomitinib là một chất ức chế EGFR tyrosin-kinase (TKIs) được chấp thuận sử dụng vào tháng 9 năm 2018 bởi FDA và vào tháng 3 năm 2019 bởi EMA làm thuốc điều trị đầu tay cho bệnh nhân trưởng thành mắc ung thư phổi dạng không tế bào nhỏ (NSCLC). Một trong số các chất trung gian quan trọng trong quy trình tổng hợp dacomitinib là acid (E)-4-(piperidin-1yl)but-2-enoic hydroclorid (LT-03). Hiện nay có nhiều tác giả quốc tế đã công bố về phương pháp tổng hợp LT-03, chủ yếu từ nguyên liệu là dẫn chất ester của acid crotonic (các alkyl crotonat). Bài báo này công bố một phương pháp mới để
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Parodi, Adriano, Alexandra Jorea, Maurizio Fagnoni, et al. "Bio-based crotonic acid from polyhydroxybutyrate: synthesis and photocatalyzed hydroacylation." Green Chemistry 23, no. 9 (2021): 3420–27. http://dx.doi.org/10.1039/d1gc00421b.

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Bio-based crotonic acid was prepared via the thermolytic distillation of polyhydroxybutyrate (PHB) and PHB-enriched bacteria, and then subjected to a photocatalyzed hydroacylation, showing a comparable reactivity with that of commercial crotonic acid.
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Danish, Isravel A., and Karnam J. R. Prasad. "Synthesis of 5-Methyl-1,2,3,4,5,6-hexahydrocyclopenta[g]carbazole-1,7- diones and Crotonyl-2-isopropyl-1-oxo-1,2,3,4-tetrahydrocarbazoles from 1-Oxo-1,2,3,4-tetrahydrocarbazoles by Friedel-Crafts Reaction." Zeitschrift für Naturforschung B 59, no. 6 (2004): 711–15. http://dx.doi.org/10.1515/znb-2004-0613.

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The reaction of 1-oxo-1,2,3,4-tetrahydrocarbazoles (1) with crotonic acid in polyphosporic acid afforded hitherto unknown 5-methyl-1,2,3,4,5,6-hexahydrocyclopenta[g]carbazole-1,7-diones (2) and 6-crotonyl-2-isopropyl-1-oxo-1,2,3,4-tetrahydrocarbazoles (3) in a single step. A plausible mechanism for the formation of the title compounds has been proposed, and all new compounds were characterized by IR, NMR, mass spectral methods and elemental analysis.
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Guseinov, K. Z., M. A. Mirzoyeva, and P. A. Aliyev. "CYANALKYLATION OF MERCAPTOACETIC ACID ESTERS." Azerbaijan Chemical Journal, no. 4 (December 8, 2021): 30–34. http://dx.doi.org/10.32737/0005-2531-2021-4-30-34.

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The addition of mercaptoacetic acid esters (MAAE) to nitriles of acrylic, methacrylic, and crotonic acids easily occurs in the presence of triethylamine as a catalyst to form the corresponding 2-cyanoal-kyl¬alkoxycarbonylmethyl sulfides
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Liu, Xing, Entezar Mehrabi Nasab, and Seyyed Shamsadin Athari. "Anti-inflammatory effect of N-(trifluoromethylphenyl)- 2-cyano-3-hydroxy-crotonic acid amide and gluconic acid on allergic rhinitis and asthma controlling." Allergologia et Immunopathologia 50, no. 6 (2022): 71–75. http://dx.doi.org/10.15586/aei.v50i6.612.

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Allergic rhinitis and asthma are the main airway diseases with a higher prevalence. Eosinophilic inflammation, airway hyperresponsiveness, mucus hypersecretion, and reversible airflow obstruction are immunopathogenesis symptoms of rhinitis and asthma. Crotonic acid has bioactivity on the inflammation, and gluconic acid as chelator may protect crotonic acid activity in airway and together may control allergic rhinitis and asthma.Allergic rhinitis and asthma mice models were treated with crotonic and gluconic acids. The total IgE, histamine, IL-4, IL-5, and IL-13 levels were measured. In lung ti
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Pulat, Mehlika, and Meliha Çetin. "Pantoprazole-Na Release from Poly(acrylamide-co-crotonic acid) and Poly(acrylic acid-co-crotonic acid) Hydrogels." Journal of Bioactive and Compatible Polymers 23, no. 4 (2008): 305–18. http://dx.doi.org/10.1177/0883911508090201.

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Helavi, V. B., S. B. Solabannavar, R. S. Salunkhe, and R. B. Mane. "Microwave-Assisted Solventless Pechmann Condensation." Journal of Chemical Research 2003, no. 5 (2003): 279–80. http://dx.doi.org/10.3184/030823403103173796.

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Solventless Pechmann condensation of various phenols with crotonic acid, malic acid, fumaric acid or maleic acid, using sulfuric acid or anhydrous zinc chloride under microwave irradiation yielded coumarins and chromanones.
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FURUYOSHI, Setsuo, Yoshito NAWA, and Nariyoshi KAWABATA. "Microbial production of 2-oxobutyric acid from crotonic acid." Agricultural and Biological Chemistry 55, no. 1 (1991): 123–28. http://dx.doi.org/10.1271/bbb1961.55.123.

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Furuyoshi, Setsuo, Yoshito Nawa, and Nariyoshi Kawabata. "Microbial Production of 2-Oxobutyric Acid from Crotonic Acid." Agricultural and Biological Chemistry 55, no. 1 (1991): 123–28. http://dx.doi.org/10.1080/00021369.1991.10870562.

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TSUKASA, Hidetaka. "Synthesis of Whisky Lactone from Crotonic Acid." Journal of Japan Oil Chemists' Society 36, no. 1 (1987): 51–53. http://dx.doi.org/10.5650/jos1956.36.51.

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Dissertations / Theses on the topic "Crotonic acid"

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Saporito, Luigi. "Valutazione degli impatti ambientali di un processo biobased nella produzione di acido crotonico." Master's thesis, Alma Mater Studiorum - Università di Bologna, 2021. http://amslaurea.unibo.it/23091/.

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L’utilizzo di biomasse come fonte di chemicals nell’industria chimica mira a rendere più sostenibili i processi industriali e i materiali prodotti. In particolare, l’acido crotonico (AC), impiegato come building block nella produzione di vernici e rivestimenti, è prodotto tradizionalmente da fonti fossili. La domanda globale ammonta a circa 1000 tonnellate ed è in continuo aumento, rendendo prioritaria l’individuazione di una sintesi alternativa e sostenibile. In questo studio, l’analisi del ciclo di vita (life cycle assessment, LCA) è stata applicata per stimare la carbon footprint e la doman
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Dal, Bó Sílvia. "Avaliação da atividade antinociceptiva da subfração 63 (SF63) obtida a partir das cascas da Croton Celtidifolius (Euphorbiaceae)." Florianópolis, SC, 2004. http://repositorio.ufsc.br/xmlui/handle/123456789/87159.

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Dissertação (mestrado) - Universidade Federal de Santa Catarina, Centro de Ciências Biológicas. Programa de Pós-graduação em Farmacologia.<br>Made available in DSpace on 2012-10-21T15:29:43Z (GMT). No. of bitstreams: 0<br>A [SF63], obtida das cascas da [Croton Celtidifolius] administrada por via intraperitoneal, provocou antinocicepção quando avaliada nos modelos de contorção abdominal induzida pelo [Ácido acético], no teste da nocicepção induzida pela [Formalina], no teste da [Capsaicina], no teste [Glutamato], no teste da [Retirada da cauda] e no modelo da [Placa quente], em doses que não pr
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Assis, Lara Clemes. "Efeito da fração rica em proantocianidinas da planta croton celtidifolius sobre a neurotoxicidade glutamatérgica." Florianópolis, SC, 2012. http://repositorio.ufsc.br/xmlui/handle/123456789/96439.

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Dissertação (mestrado) - Universidade Federal de Santa Catarina, Centro de Ciências Biológicas. Programa de Pós-Graduação em Farmacologia.<br>Made available in DSpace on 2012-10-26T12:04:35Z (GMT). No. of bitstreams: 1 302042.pdf: 693987 bytes, checksum: 823b44b5d3f07e3feb6ab9f9b1c8df9d (MD5)<br>Glutamato, o principal neurotransmissor central excitatório, induz excitotoxicidade neuronal pela ativação de receptores NMDA e AMPA, promovendo o influxo de cálcio nos neurônios. Estudos recentes do nosso grupo demonstram que as frações e sub-frações isoladas da Croton celtidifolius possuem propriedad
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Almeida, Jean Sardinha de. "Aditivos fitogênicos e ionóforos na degradabilidade da fibra e parâmetro metabólicos em bovinos." Universidade Federal de Goiás, 2016. http://repositorio.bc.ufg.br/tede/handle/tede/5773.

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Submitted by Marlene Santos (marlene.bc.ufg@gmail.com) on 2016-07-29T18:15:18Z No. of bitstreams: 2 Disssertação - Jean Sardinha de Almeida - 2016.pdf: 1339332 bytes, checksum: 418c173cb4b8d6405108b91607c5d13d (MD5) license_rdf: 0 bytes, checksum: d41d8cd98f00b204e9800998ecf8427e (MD5)<br>Approved for entry into archive by Luciana Ferreira (lucgeral@gmail.com) on 2016-08-01T13:32:48Z (GMT) No. of bitstreams: 2 Disssertação - Jean Sardinha de Almeida - 2016.pdf: 1339332 bytes, checksum: 418c173cb4b8d6405108b91607c5d13d (MD5) license_rdf: 0 bytes, checksum: d41d8cd98f00b204e9800998ecf8427e (MD5)
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Mamvura, Chiedza Isabel. "Poly-(vinylpyrrolidone)-poly-(vinylacetate-co-crotonic acid) (PVP : PVAc-CA) interpolymer complex microparticles encapsulating a Bifidobacterium lactis Bb12 probiotic strain: microparticle characterization and effect on viability of encapsulated probiotic cells." Diss., 2012. http://hdl.handle.net/2263/29325.

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Microorganisms have been known to play a major role in human health since early times. The ingestion of microorganisms as probiotics to restore and/or maintain health is a widely accepted and common practice. The challenge in industry is to ensure viability of probiotics until their ingestion to their site of action, the colon, for health benefits to be realised. Microencapsulation is one of the techniques used to protect probiotic bacteria and ensure viability. A method that does not involve the use of extreme temperatures and/or solvents which would otherwise adversely affect viable cells wa
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Book chapters on the topic "Crotonic acid"

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Gooch, Jan W. "Crotonic Acid." In Encyclopedic Dictionary of Polymers. Springer New York, 2011. http://dx.doi.org/10.1007/978-1-4419-6247-8_3133.

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Lide, David R. "trans-Crotonic acid." In Handbook of Organic Solvents. CRC Press, 2024. http://dx.doi.org/10.1201/9781003575191-102.

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Holze, Rudolf. "Ionic conductance of crotonic acid." In Electrochemistry. Springer Berlin Heidelberg, 2016. http://dx.doi.org/10.1007/978-3-662-49251-2_465.

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Bährle-Rapp, Marina. "VA/Crotonic Acid/PEG-20M Copolymer." In Springer Lexikon Kosmetik und Körperpflege. Springer Berlin Heidelberg, 2007. http://dx.doi.org/10.1007/978-3-540-71095-0_10939.

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Holze, Rudolf. "Ionic conductance of trans-crotonic acid." In Electrochemistry. Springer Berlin Heidelberg, 2016. http://dx.doi.org/10.1007/978-3-662-49251-2_466.

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"Crotonic acid." In Encyclopedic Dictionary of Polymers. Springer New York, 2007. http://dx.doi.org/10.1007/978-0-387-30160-0_3080.

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Taber, Douglass. "Alkene Metathesis: Synthesis of Kainic Acid, Pladienolide B and Amphidinolide Y." In Organic Synthesis. Oxford University Press, 2011. http://dx.doi.org/10.1093/oso/9780199764549.003.0028.

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As alkene metathesis has developed into one of the tools of organic synthesis, many practical questions have arisen. In the course of a synthesis (Organic Lett. 2007, 9, 1635) of the important neuropharmacological tool (-)-kainic acid 7, Tohru Fukuyama of the University of Tokyo prepared the key intermediate 1 by chiral auxiliary mediated coupling of crotonyl chloride with acetadehyde. Dibal reduction gave the hemiaminal, which underwent reductive amination with glycine methyl ester, leading to the alkene 2. Alkene metathesis of the derived ester 3 to form the unsaturated lactone 4 was then ex
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Taber, Douglass. "The Carter Synthesis of (-)-Lycopodine." In Organic Synthesis. Oxford University Press, 2011. http://dx.doi.org/10.1093/oso/9780199764549.003.0099.

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Rich G. Carter of Oregon State University described (J. Am. Chem. Soc. 2008, 130, 9238) the first enantioselective synthesis of the Lycopodium alkaloid (-)-lyopodine 3. A key step in the assembly of 3 was the diastereoselective intramolecular Michael addition of the keto sulfone of 1 to the enone, leading to the cyclohexanone 2. The key cyclization substrate 1 bore a single secondary methyl group. While that could have been derived from a natural product, it was operationally easier to effect chiral auxiliary controlled conjugate addition to the crotonyl amide 4, leading, after methoxide excha
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Conference papers on the topic "Crotonic acid"

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Kyhoiesh, Hussein Ali Kadhim, Mohammed K. Al-Hussainawy, and Haider Radhi Saud. "Synthesis and characterization of polyacrylamide/crotonic acid and its composites with carbon nanotube and Rhodamine B." In PROCEEDING OF THE 1ST INTERNATIONAL CONFERENCE ON ADVANCED RESEARCH IN PURE AND APPLIED SCIENCE (ICARPAS2021): Third Annual Conference of Al-Muthanna University/College of Science. AIP Publishing, 2022. http://dx.doi.org/10.1063/5.0093386.

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Reports on the topic "Crotonic acid"

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จันทรทิณ, เพชรรัตน์, อัจฉริยา มณีน้อย та วีระเดช สุขเอียด. การคัดเลือกต้นเปล้าน้อยที่ได้จากการเพาะเลี้ยงเนื้อเยื่อ ให้ต้านทานต่อสารพิษของเชื้อรา Glomerella cingulata : รายงานผลการวิจัย. จุฬาลงกรณ์มหาวิทยาลัย, 1999. https://doi.org/10.58837/chula.res.1999.81.

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โรคใบจุดของเปล้าน้อย (Croton sublyratus Kurz.) เกิดจากเชื้อรา Glomerella cingulata โดยมี Colletotrichum gloeosporioides เป็น imperfect stage เชื้อราสามารถเจริญและสร้างสปอร์ได้ดีบนอาหาร Czapek agar (CZA) น้ำหนักแห้งของเส้นใยและปริมาณสารสกัดจากเชื้อรามีมากที่สุดเมื่อเลี้องเชื้อในอาหารเหลว Czapek dox medium เป็นเวลา 4 วัน ในการทดสอบความเป็นพิษของสารสกัดจากเชื้อราโดยวิธีการหยดสารสกัดจากเชื้อราลงบนใบเปล้าน้อยพบว่า สารสกัดจากเชื้อราความเข้มข้น 10,000 มิลลิกรัมต่อลิตร สามารถทำให้เกิดอาการใบจุดกับเปล้าน้อยได้ จากการวิเคราะห์สารสกัดจากเชื้อราด้วยวิธี HPLC พบว่า เชื้อรา Glomerella cingulata สามารถสร้างส
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