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1

Potros, Benjamin. "Whole Body Cryotherapy och träningsvärk : Vad har Whole Body Cryotherapy för effekt på träningsvärk." Thesis, Högskolan i Gävle, Idrottsvetenskap, 2017. http://urn.kb.se/resolve?urn=urn:nbn:se:hig:diva-24268.

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Intensiv träning resulterar iskada i skelettmuskulaturen. Symptomen som idrottare uppvisar efter träning är svullnad, smärta och nedsatt muskelfunktion. Användningen av Whole Body Cryotherapy(WBC) har uppmärksammats och används för att återhämta sig från de symptom som orsakas vid Delayed Onset Muscle Soreness(DOMS). Syftet med denna litteraturstudie var att se vilken effekt WBC har på DOMS. Litteratursökningen ägde rum i PubMed, Cinahl och Google Scholars databaser. Utfallsvariabler som testade för DOMS var smärta registrerat med Visual Analog Scale(VAS), Maximal genererad kraftkapacitet(MKK) och blodprover som testade för inflammatoriska ämnen CreatinCinase(CK) och inflammatoriska cytokiner. Litteratursökningen resulterade i nio artiklar. Fem av de totalt nio studierna som hade smärta som en utfallsvariabel visade en minskad smärta för WBC-guppen jämfört med kontrollgruppen. Studier som undersökte MKK var motsägelsefulla. Tre av sex studier som undersökte MKK visade en signifikant skillnad på WBC gruppen, samtidigt visade de tre resterande studierna ingen effekt alls. Studier som haft CK och inflammatoriska cytokiner som utfallsvariabel visade ingen effekt. Sammanfattningsvis visade det sig att WBC har liten och ingen effekt på DOMS. Området saknar fortfarande forskning och detta område behöver undersökas mer innan WBC kan rekommenderas som en effektiv återhämtningsmetod mot DOMS, och hittills har metoden visar liten eller ingen effekt på dessa utfallsvariabler
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Ismail, Mohamed Said. "Molecular and immunological effects of prostate cancer cryotherapy." Thesis, University of Surrey, 2009. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.502656.

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Chen, Yingxin, Weijia Yang, Minghong Gao, Michael Wellington Belin, Hai Yu, and Jing Yu. "Experimental study on cryotherapy for fungal corneal ulcer." Springer, 2015. http://hdl.handle.net/10150/610295.

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BACKGROUND: Fungal corneal ulcer is one of the major causes of visual impairment worldwide. Treatment of fungal corneal ulcer mainly depends on anti-fungal agents. In the current study, we developed an integrated combination therapy of cryotherapy and anti-fungal agents to facilitate effective treatment of fungal corneal ulcer. METHODS: Rabbit models of cornea infection were established using a combined method of intrastromal injection and keratoplasty. After treatment with cryotherapy and anti-fungal agents, scanning electron microscopy, transmission electron microscopy, and confocal microscopy were conducted to observe changes in microstructure in the rabbits. Periodic acid Schiff A and hematoxylin and eosin staining were used for detection of histological changes. RESULTS: Continuous scanning electron microscopy and transmission electron microscopy observations showed that cryothermal treatment inhibited growth of fungal mycelium by destroying fungal cellular structures. Typical cryotherapy was effective in curing fungal corneal ulcer. Different fungi showed different susceptibilities to treatment. The curative effect of Candida albicans was the best, while that of Aspergillus fumigates was the worst. CONCLUSIONS: Our study provides a novel method of a combination of cryotherapy and anti-fungal agents for treatment of fungal corneal ulcer. This treatment could help facilitate the practice of fungal keratitis treatment in the future.
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Long, Blaine Cletus. "Motor Function Responses to Induced Pain and Cryotherapy." Diss., CLICK HERE for online access, 2008. http://contentdm.lib.byu.edu/ETD/image/etd2394.pdf.

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Westerlund, T. (Tarja). "Thermal, circulatory, and neuromuscular responses to whole-body cryotherapy." Doctoral thesis, University of Oulu, 2009. http://urn.fi/urn:isbn:9789514290435.

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Abstract The purpose of this study was to examine thermal (body temperature, thermal sensation and comfort ratings), circulatory (blood pressure, heart rate variability) and neuromuscular performance responses to whole-body cryotherapy (WBC, -110 °C). Altogether 66 healthy subjects were exposed to WBC for two minutes. The acute and long-term changes were examined, when the subjects were exposed to WBC three times a week during three months. Skin temperatures decreased very rapidly during WBC, but remained such a high level that there was no risk for frostbites. The effects on rectal temperature were minimal. Repeated exposures to WBC were mostly well tolerated and comfortable and the subjects became habituated at an early stage of trials. WBC increased both systolic (24 mmHg) and diastolic (5 mmHg) blood pressures temporarily. Adaptation of blood pressure was not found during three months. The acute cooling-related increase in high-frequency power of RR-intervals indicated an increase in cardiac parasympathetic modulation, but after repeated WBC the increase was attenuated. The repeated WBC exposure-related increase in resting low frequency power of RR-intervals resembles the response observed related to exercise training. There are signs of neuromuscular adaptation, especially in dynamic performance. A single WBC decreased flight time in drop-jump exercise, but after repeated WBC these changes were almost vanished. This adaptation was confirmed by the change of the activity of the agonist muscle, which increased more and the change of the activity of antagonist muscle, which increased less/did not change after repeated WBC indicating reduced co-contraction and thus, neuromuscular adaptation.
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Miniello, Susan E. "Does ankle cryotherapy affect dynamic stability of healthy subjects?" [Gainesville, Fla.] : University of Florida, 2003. http://purl.fcla.edu/fcla/etd/UFE0001078.

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7

Rose, Catriona Louise. "Whole Body Cryotherapy as a Recovery Intervention for Athletes." Thesis, The University of Sydney, 2019. http://hdl.handle.net/2123/20715.

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Recovery protocols including cold water immersion (CWI) and whole-body cryotherapy (WBC), are to minimise the impact of symptoms of exercise induced muscle damage (EIMD) after damaging exercise. This thesis aimed to systemically review the current body of knowledge on the efficacy of WBC as a recovery tool after EIMD; investigate the effect of a single 3min WBC or CWI exposure on peripheral blood mononuclear cell (PBMC) redistribution; and assess the effectiveness of WBC as a recovery treatment in comparison to CWI, after eccentric exercise. It is hypothesised that WBC may enhance the beneficial effects of cold recovery treatments that reduce the time take to recover from symptoms of EIMD. Mobilisation of immune cells required for recovery may be influenced by the colder temperatures of WBC is hypothesised to assist in athlete’s recovery. A systematic review on the literature (Chapter Two) found that despite methodological variations within studies, WBC reduced pain and improved muscle function after EIMD, with small, but significant, improvements in some markers of inflammation and muscle damage. The second study (Chapter Three) found a significant increase in PBMC subsets, CD8+ T cells (p=0.02) and CD56-CD16+ NK cells (p=0.01), after WBC compared to CWI and a control. Lastly, a randomised control trial found that neither WBC, nor CWI, improved the recovery of pain and muscle function, as well as concentrations of blood biomarkers such as CK and inflammatory mediators and cytokines after damaging exercise compared to the control. Despite these findings suggesting that a single WBC exposure does not influence the recovery of these markers of EIMD, the transient increase in PBMCs may in fact be beneficial in facilitating the process. Exposure to WBC may increase the availability of immune cells in circulation to affect the regenerative process after EIMD. These findings therefore add new avenue to the study of WBC in the context of recovery following exercise.
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Шамрай, А. В. "Применение криотерапии в спорте." Thesis, Сумский государственный университет, 2013. http://essuir.sumdu.edu.ua/handle/123456789/41055.

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Организация и планирование тренировочного процесса, а также подготовка спортсменов высокого уровня наиболее часто осложняется в связи с получением спортивных травм, особенно острого и хронического характера. Снятие боли в первые секунды после получения травмы, снижение негативных последствий, особенно от специфических спортивных травм, присущих отдельным видам спорта, остается очень актуально.
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Перешивайло, А. И. "Криотерапия." Thesis, Сумский государственный университет, 2013. http://essuir.sumdu.edu.ua/handle/123456789/41026.

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Криотерапия - это лечение холодом, метод оздоровления и омоложения организма. Появление этого метода стало прорывом в области медицины. Криотерапия очень удобна. Так общая криотерапии, базируется на самодиагностике, когда организм сам выбирает и направляет действие холода в ту область, где есть нарушения, оказывает благоприятное воздействие на весь покров кожи и влияет на центральную нервную систему. При локальной криотерапии, при которой используются специальные переносные аппараты и криопакеты, что очень актуально для оказания неотложной медицинской помощи.
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Bhardwaj, Neil. "Ablation of liver tissue : a comparison between microwave, cryotherapy and radiofrequency." Thesis, University of Leicester, 2011. http://hdl.handle.net/2381/9509.

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Introduction The majority of primary and secondary liver tumours are inoperable. „In situ‟ thermal destruction techniques such as radiofrequency, microwave ablation and cryotherapy have been employed to treat these inoperable tumours. Despite recent advances in these technologies, large and peri-vascular tumours still suffer from a relatively high recurrence rate post ablation. This is thought to be due to the loss of thermal energy to surrounding vasculature, known as the heat sink effect. The aim of this project was to investigate the effect of surrounding vasculature on ablation morphology and success and compare the three most popular ablation modalities. Methods Standard sized ablations were created in rat liver at various distances from the hilum with all three methods. At various time points, tissue samples were retrieved and underwent histological (H&E) and immuno-cytochemical (Hsp70 and Caspase 3) staining in order to assess lesion evolution and the effects of surrounding vasculature on ablation completeness. Results All rats survived. The greatest amount of activity was seen in the transition zone. H&E and immuno-cytochemical analyses of lesion evolution discovered previously unreported cellular changes, particularly in the transition zone. Cryotherapy ablation seemed to be the most irregular and unpredictable of the three. Radiofrequency ablation was uniform but showed evidence of extra-lesional apoptosis and perivascular cell survival in addition to Hsp 70 activity in the transition zone that was affected by surrounding vasculature. Microwave ablation seemed to be influenced least by surrounding vasculature and formed the most uniform lesion with very little extra-lesional collateral damage. Conclusion The success of ablation is dependent upon the adjacent blood vessels and microwave ablation seemed to form the most predictable burn and be least affected by surrounding vasculature compared to radiofrequency. Cryotherapy should not be used as first line treatment to treat unresectable liver tumours. In addition the exact role of HSP 70 on the fate of cells in the transition zone, and the subsequent final ablation size and morphology is yet to be determined. Larger ablations in larger animal models may help answer some of these questions.
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Hatzel, Brian M. "Effects of cryotherapy and ankle taping on mechanical power and velocity." Virtual Press, 1999. http://liblink.bsu.edu/uhtbin/catkey/1136705.

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Athletic trainers frequently are required to design rehabilitation and treatment programs for injured athletes. These treatment programs oftentimes involve the use of cryotherapy or ankle taping to create an optimal environment for healing. The purpose of this study was to identify the individual and simultaneous effects of ankle taping and cryotherapy on mechanical power and velocity.Sixteen (16) Division IA Baseball players (Age 20.53+/- 1.15 yrs, Wt 878.45+/105.68 N, Ht 1.85+/- 0.087 m) served as subjects for this study. Subjects met the following criteria: 1) all were asymptomatic from any lower extremity injury for at least six months prior to testing. 2) none had any known cold allergy (ie. hives, hypersensitivity to cold).This study utilized a counterbalanced repeated measures design, in which subjects participated in three treatments, cryotherapy, ankle taping and a combination treatment of cryotherapy and ankle taping. For the taping treatment, each subject was taped using a standard closed basket weave technique` with porous 1.5" cloth athletic tape (Johnson and Johnson, Coach). The cryotherapy treatment was administered a 20 minute ice immersion treatment at 10 deg Celsius to the leg and ankle. In the combination treatment, both treatments were administered with the ice immersion preceding ankle taping. The effects of these treatments on mechanical power and velocity were measured by a Kistler amplifier and force plate platform during a one leg standing vertical jump.The two-way repeated measures ANOVA's for power and velocity showed no significant interaction between cryotherapy, taping or combination treatment. However, significant pre-post treatment effects for power were discovered after cryotherapy and combination treatment. As a result of these findings, it is evident that immediate return to participation after cryotherapy or combination treatment will lead to decreases in muscular performance or injury.
School of Physical Education
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Barry, Simon John. "An investigation into the effectiveness of cryotherapy following total knee replacement." Thesis, Coventry University, 2004. http://curve.coventry.ac.uk/open/items/ca73885a-2912-95ea-d424-c7a5e1c3c06a/1.

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Background: Cryotherapy is commonly used during physiotherapeutic rehabilitation of patients following total knee replacement (TKR). Evidence for treatment effectiveness within the current literature is contradictory and there are no clinical guidelines to inform cryotherapy treatment within this particular patient group. This study surveys current cryotherapy treatment efficacy in the acute post-operative management of TKR patients. Methods: In total 263 senior physiotherapists completed and returned a postal questionnaire, which, using open and closed questions investigated the use of cryotherapy following TKR. Survey results were used to inform a pragmatic randomized clinical trial (RCT) involving 133 consecutive TKR patients. The RCT investigated cryotherapy treatment efficacy in the acute post-operative management of TKR patients. Patients were randomized into three groups; no cryotherapy (NC), delayed cryotherapy (DC) and immediate cryotherapy (IC). The primary outcome measure was post-operative pain with knee swelling, active range of motion (AROM), function and levels of physiotherapy input assessed as secondary outcome measures. Observations were taken pre-operatively and at 3, 7 and 42 days post-operatively. Results: The survey reported that 33% of respondents used some form of cryotherapy routinely following TKR surgery. The two main methods of cryotherapy application were Cryocuff (59%) and crushed ice (30%). Treatments were most frequently applied between 24 hrs and 48 hrs post-surgery for 20 minutes, twice a day. Chi square analysis indicated significant differences (p<0.01) in between NHS and private sites relating to a lack of cryotherapy resources and treatment time for cryotherapy in the NHS. A lack of proven efficacy was the most cited reason for not applying cryotherapy treatment, and swelling the most common treatment indicator. There was particular uncertainty regarding the cleaning and sterilization of the Cryocuff device. The RCT indicated that patients in IC group had significantly less post-operative pain than the NC and DC groups at 3 days. Mean difference (p <0.05, 95% CI) in post-operative analogue scores (VAS, scale 0-10) was -1.6 (p <0.01, CI -2.49- to -0.707) for IC and NC; and -0.922 (p= 0.044, CI -0.183 to -0.009) for IC and DC groups. At 7 and 42 days there were significant reductions in VAS scores for both cryotherapy groups compared to the NC group. There was significant improvement in knee swelling, AROM, ability to transfer and need for additional physiotherapy in both cryotherapy treatment groups although no significant reduction in opiate requirement was found. Conclusions: In current clinical practice there was little consensus regarding treatment indicators, method of application and management of cryotherapy following TKR. However, in a RCT the use of cryotherapy combined with compression, as compared to a no cryotherapy control, led to significant reductions in patient reported pain, less post-operative swelling, greater recovery of AROM, faster return of function and less reliance on OPD physiotherapy treatment. It is concluded that cryotherapy combined with compression has an important role to play in the acute rehabilitation of TKR and should be considered as part of routine management.
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Johnston, Christopher David. "The Effects of Cryotherapy on Quadriceps Corticospinal Excitability in Patients withPatellofemoral Pain." University of Toledo / OhioLINK, 2013. http://rave.ohiolink.edu/etdc/view?acc_num=toledo1364470552.

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Ammer, Kurt. "Thermological studies in rehabilitation and rheumatology using computerised infrared imaging." Thesis, University of South Wales, 2000. https://pure.southwales.ac.uk/en/studentthesis/thermological-studies-in-rehabilitation-and-rheumatology-using-computerised-infrared-imaging(57079205-fa4b-4317-a4c3-a11ec1ca545a).html.

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This overview reports 31 studies, which have been performed by the author since 1989 to define the diagnostic value of thermometry and infrared imaging in rehabilitation and rheumatology. Some investigations were designed to characterise either treatment modalities, to clarify the role of temperature measurements as a method for follow-up or treatment monitoring in certain diseases. Thermal imaging has an important impact in assisting the diagnosis of many diseases. A relationship between temperature and clinical signs was established in the following disorders: epicondylitis (correlation of hot spots with pain provocated by firm pressure or resisted movement, and pressure threshold), complex regional pain syndrome (elevated temperature is paralleled by swelling and pain, temperature elevation of the hand after radius fracture after plaster removal predicts typical X-ray changes), thoracic outlet syndrome (high correlation of the region of paresthesia and low temperature readings), muscular inactivity, acute stage of Herpes zoster and Raynaud's phenomenon. Thermal imaging is of little value for the assessment of disability in patients with knee pain and of questionable value in patients with carpal tunnel syndrome or fibromyalgia. Painful tendon insertions or acupuncture points on the auricle cannot be detected by thermal imaging. Temperature signs in epicondylitis, complex regional pain syndrome and thoracic outlet can be successfully used for treatment monitoring. This might be also the case in radiotherapy of malignant breast disease. Infrared thermography, performed immediately after physical exercise can help to identify activated muscles. The value of thermal imaging for monitoring patients with lymphedema remains questionable. Temperature signs in epicondylitis, complex regional pain syndrome and thoracic outlet can be successfully used for treatment monitoring. This might be also the case in radiotherapy of malignant breast disease. Infrared thermography, performed immediately after physical exercise can help to identify activated muscles. The value of thermal imaging for monitoring patients with lymphedema remains questionable. On the other hand as a result of these studies, it became quite clear that the heat regulatory system is connected with other regulation systems of the body. Many of these influence the perfusion of vessels, which can result in temperature changes on the surface. In addition to the circulation system, pain and muscle function are the most important links to temperature regulation. Therefore any change or therapeutic modification of these systems might be seen on thermal images.
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Baptista, João Paulo Fonseca. "Efeito da “Whole-Body Cryotherapy” na recuperação física pós exercício: revisão de bibliografia." Bachelor's thesis, [s.n.], 2018. http://hdl.handle.net/10284/7085.

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Projeto de Graduação apresentado à Universidade Fernando Pessoa como parte dos requisitos para obtenção do grau de Licenciado em Fisioterapia
Objetivo: esta revisão da literatura teve como foco perceber de que forma e em que variáveis, o uso da whole-body cryotherapy (WBC) pode ter impacto na recuperação física após o exercício. Metodologia: foi realizada uma pesquisa computorizada nas bases de dados PubMed e Science Direct, utilizando as palavras-chave: “whole-body cryotherapy” OR “whole-body cryostimulation” AND “recovery”. Os critérios de inclusão foram: estudos randomizados controlados, publicados na língua inglesa, que falassem só na WBC, que incluíssem atletas e não atletas. Como critérios de exclusão foram utilizados: artigos focados marcadores inflamatórios e artigos que não contemplassem variáveis relacionadas com fisioterapia. Resultados: foram incluídos 7 estudos randomizados controlados. Os artigos incluídos apresentaram uma média 6,43 de na escala PEDro. Dos artigos analisados, os 7 abordaram o impacto da WBC na performance desportiva bem como nas sensações subjetivas, 4 abordaram também o impacto da técnica sobre a creatina quinase e apenas 1 avaliou o impacto sobre a qualidade do sono. Conclusão: podemos concluir que a WBC poderá ter lugar como modalidade de recuperação física no âmbito do exercício. No entanto, pelo facto dos estudos sobre esta recente modalidade não serem consensuais, maior investigação será necessária.
Objective: This review of the literature aimed to understand how and in what variables, the use of whole-body cryotherapy could impact physical recovery after exercise. Methodology: A computerized search was performed based on PubMed and Science Direct databases, using the keywords: “whole-body cryotherapy” OR “whole-body cryostimulation” AND “recovery”. The inclusion criteria were: randomized control trials, published in the English language, highlighting only WBC, that involved athletes or non-athletes. The exclusion criteria were studies focused on inflammatory markers and studies that didn´t approach physiotherapy related variables. Results: 7 randomized control trials were included. The articles had an average of 6,43 on the PEDro scale. All 7 articles analyzed assessed sport performance and subjective sensations, 4 also assessed the impact of WBC on creatine kinase and only 1 assessed the impact of the technique on sleep quality. Conclusion: We can conclude that WBC could have a place as a recovery modality regarding exercise. However, because not all trials were consensual, more investigation on the matter is necessary.
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Hansson, Björn. "The effects of cryotherapy on work-capacity during repeated sets of leg-extentions." Thesis, Mittuniversitetet, Avdelningen för hälsovetenskap, 2016. http://urn.kb.se/resolve?urn=urn:nbn:se:miun:diva-27986.

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Іващева, Ю. Ю. "Кріотехнології." Thesis, Сумський державний університет, 2014. http://essuir.sumdu.edu.ua/handle/123456789/38804.

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Лікувальні властивості холоду, відомі з часів давнини, але за останні роки вони суттєво вдосконалилися. Кріотехнології – лікування захворювань холодом ( рідкий азот, лід, гелій, кисень, холодна вода). В даній роботі ми з’ясуємо: наскільки кріотехнологія є ефективною в лікуванні та в яких напрямках медицини вона застосовується, зокрема в косметології.
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Kunisch, Robert W. "the Effects of Cryotherapy on Quadriceps Corticomotor Excitability in Patients with Anterior Knee Pain." University of Toledo / OhioLINK, 2015. http://rave.ohiolink.edu/etdc/view?acc_num=toledo1430473379.

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Ruck, Meredith L. "A Comparison of Cryopress and Cryo-Cuff Effects on Ankle Edema and Pain." Ohio University / OhioLINK, 2005. http://rave.ohiolink.edu/etdc/view?acc_num=ohiou1126214268.

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Cameron, Shawn P. "Focal Wrist Cooling Does Not Alter Indices of Spinal Excitability in the Flexor Carpi Radialis Muscle." Ohio University / OhioLINK, 2011. http://rave.ohiolink.edu/etdc/view?acc_num=ohiou1306953575.

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DE, NARDI MASSIMO. "Partial Body Cryotherapy in the context of medicine, health and sports: studies on practical applications." Doctoral thesis, Università degli studi di Genova, 2019. http://hdl.handle.net/11567/982388.

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The purpose of this study was to examine isometric strength, pain threshold and perceived health responses to partial-body cryotherapy (PBC, 150s at a temperature range between -130 and -160°C). Three different populations of subjects were enrolled for this study: 200 healthy people were exposed to a single PBC session in order to assess the maximum handgrip isometric strength responses by means of an hydraulic dynamometer, 30 healthy female carried out a cycle of ten consecutive PBC sessions for evaluate the objective pain threshold in the low back region via the painpressure test and finally 28 female fibromyalgic patients were exposed to repeated exposure to PBC (ten sessions in a row) with the purpose to examine perceived health and quality of life responses utilizing two self-reported questionnaires. A single session of PBC lead to improve, immediately after the very-low temperatures exposure, muscle isometric strength in healthy people both in females and in males. Repeated exposures to PBC in healthy women was shown to be efficient in decreasing very rapidly the skin temperature in the lowback region, and thus to induce a significant increase in pain-pressure threshold values. The same protocol of repeated exposures to PBC induced significant improvements for all indexes and sub-indexes of the perceived health and quality of life questionnaires assessed in fibromyalgic patients.
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Poon, Sze-wan, and 潘詩尹. "An evidence-based guideline on using cryotherapy for chemotherapy-induced oral mucositis in adult cancer patients." Thesis, The University of Hong Kong (Pokfulam, Hong Kong), 2012. http://hub.hku.hk/bib/B48339192.

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Oral mucositis is a common adverse side-effect caused by cancer treatments and can lead to mucosa toxicity. Patients with oral mucositis may experience extreme pain and may not be able to eat, drink and talk and, as a result, their quality of life is impaired. Thirty to eighty five percent of patients undergoing chemotherapy would develop oral mucositis. Preventing or reducing incidence of oral mucositis and its severity can help reduce patients’ sufferings. One of the methods to achieve this objective is the oral cryotherapy, which is a prophylactic intervention. However, there is no evidence-based guideline to instruct nurses on providing oral cryotherapy to cancer patients. The aims of this study are 1) to establish an evidence-based guideline on applying cryotherapy to reduce the incidence and severity of chemotherapy-induced oral mucositis, 2) to develop a standard nursing care and assess its transferability and feasibility, and 3) to develop a communication plan and evaluation plan for this guideline in an oncology ii- department for the targeted local hospitals in Hong Kong. A systematic search of four electronic journal databases identified seven articles corresponding to 6 randomized controlled trials (RCTs) on using oral cryotherapy for adult cancer patients. Five RCTs with high to weak quality reported supporting evidence for the beneficial effect of oral cryotherapy on chemotherapy-induced oral mucositis, whereas 1 RCT with moderate quality failed to identify supportive evidence for the use of oral cryotherapy. However, potential confounding factors were identified to be presented in that insignificant RCT. Hence, there was sufficient evidence to show that oral cryotherapy can significantly reduce chemotherapy-induced oral mucositis in adult cancer patients. An evidence based guideline for using cryotherapy on chemotherapy-induced oral mucositis in adult cancer patients was established. The transferability and feasibility of the proposed oral cryotherapy guideline were assessed. As identified, the clinical situation and patient characteristics in the local settings are similar to those who reported in the reviewed studies. Staff readiness, skills and resources are also readily available in the target clinical settings. Findings from the reviewed studies of oral cryotherapy can be transferred to the local target settings and are feasible to be implemented. It is also estimated that the innovated guidelines for cryotherapy can save HK$3,210,745 per year for the target setting. Stakeholders for the innovated guideline in the local setting were identified. And a communication plan was developed. A pilot study lasting for 10 weeks will be conducted to test the feasibility of the staff training session and the implementation of the oral cryotherapy guideline. Modification of innovated guidelines will be made after evaluating the data collected from the pilot study. Eventually, the final version of the evidence-based guideline will be established. A six months evaluation plan will be used to evaluate the implementation of the new guideline. The policy for adopting the oral cryotherapy will be determined with the outcome measures, including the incidence of chemotherapy-induced oral mucositis, mean of the oral mucositis score, staff satisfaction level, and the cost and benefit ratio of the innovated guideline.
published_or_final_version
Nursing Studies
Master
Master of Nursing
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Hanai, Akiko. "Effects of Cryotherapy on Objective and Subjective Symptoms of Paclitaxel-Induced Neuropathy: Prospective Self-Controlled Trial." Kyoto University, 2018. http://hdl.handle.net/2433/232318.

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TERASAKI, HIROKO, SHU KACHI, YOSHIKO TAKAI, MINEO KONDO, KOTA SUGIMOTO, CHIEKO FUJIOKA, HIROKI KANEKO, and SAYOKO IWASE. "A Long-term Follow-up of Patients with Retinopathy of Prematurity Treated with Photocoagulation and Cryotherapy." Nagoya University School of Medicine, 2014. http://hdl.handle.net/2237/19490.

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Carneiro, Mário Brandão [UNESP]. "Equipamento de hipotermia para ser utilizado em tratamento muscular com lesões na fase aguda." Universidade Estadual Paulista (UNESP), 2010. http://hdl.handle.net/11449/97037.

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Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)
A idéia da realização deste trabalho e do desenvolvimento do equipamento por ele apresentado surgiu a partir da necessidade de se obter um dispositivo que substituísse a utilização do gelo no tratamento de lesões muscuesqueléticas. Esta terapia, muito utilizada desde tempos passados, vem do conceito da crioterapia, que nada mais é do que o uso do frio para diminuição da temperatura dos tecidos corporais e, conseqüentemente, o tratamento de lesões agudas. A crioterapia tem a função de reduzir a dor e o espasmo muscular e de proporcionar a vasoconstrição, evitando a contaminação dos tecidos ao seu redor. Seu objetivo principal é retirar calor corporal através do resfriamento da região lesionada de modo a influenciar na reação inflamatória aguda. A remoção do calor corporal se dá através da transferência de calor entre o equipamento e o corpo humano, ou seja, pelo o fator de condutividade térmica de cada superfície. Para obtenção de um equipamento que pudesse gerar baixa temperatura, foi abordado o estudo de dispositivos termoelétricos, sobretudo das células Peltier, que são capazes de gerar tanto baixa quanto alta temperatura. Isto se dá através da junção de dois condutores de materiais diferentes alimentados por uma tensão elétrica em circuito fechado. Baseado na necessidade de praticidade, este trabalho apresenta o estudo da crioterapia, de dispositivos termoelétricos, sob o conceito de troca de calor, propondo um equipamento de fácil manejo e serão apresentados os resultados dos testes realizados como o equipamento, suas características e vantagens
The idea of this work carrying out and the equipment development introduced by it arose from the need to obtain a device that replaces the application of ice to treat Musculoskeletal injuries. This therapy, widely used since ancient times, comes from the concept of cryotherapy, which is nothing more than the use of cold to decrease the temperature of body tissues and, consequently, the treatment of acute injuries. Cryotherapy has the function to reduce the pain and muscle spasm and provide vasoconstriction, preventing contamination of surrounding tissues. Its main objective is to remove body heat by cooling of the injured area in order to influence the acute inflammatory reaction. The removal of body heat is through heat transfer between the equipment and the human body, ie, by the factor of thermal conductivity of each surface. To achieve a device that could generate low temperature, was approached the thermoelectric devices study, especially from the Peltier cells, which are able to generate both low as high temperature. This occurs through the junction between two conductors of different materials supplied by a voltage in a closed circuit. Based on the need of convenience, this work presents a cryotherapy study, from thermoelectric devices, under concept of heat exchange, proposing a device easy to handle and will present the results of testing the equipment, its characteristics and advantages
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26

Peres, Daniele. "Elaboration et évaluation d’un programme d’exercice aérobie sur cycloergomètre et de sa récupération immergée chez le patient atteint de polyarthrite rhumatoïde." Thesis, Bourgogne Franche-Comté, 2018. http://www.theses.fr/2018UBFCE017.

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La polyarthrite rhumatoïde (PR) est une maladie inflammatoire, auto-immune, chronique et systémique avec la présence d’arthrites et synovites périphériques. Une autre conséquence sévère de la maladie et de ses traitements est la présence d’une rigidité artérielle élevée précoce, par conséquent une haute incidence de problèmes cardiovasculaires pour les sujets atteints. La pratique d'exercices physiques (EP) est reconnue comme une des thérapies non-pharmacologiques les plus efficaces pour lutter contre le risque cardiovasculaire. Cependant la population PR présente un bas niveau de pratique d’activité physique et les programmes d’EP sont rarement proposés dans la prise en charge thérapeutique de ces patients. Pour dépasser cette problématique l’association de la cryothérapie à un programme d’EP adapté semble être une stratégie intéressante. L’objectif de ce travail était de concevoir et de tester un programme d’EP associé à de la cryothérapie adapté aux patients PR afin de lutter contre le risque cardiovasculaire.A partir d’une revue systématique, nous avons montré le caractère lacunaire de la littérature en termes de programme d’EP associé à de la cryothérapie pour des patients PR, le manque de consensus sur les méthodes utilisées aussi bien pour le type d’EP à proposer que pour les méthodes de cryothérapie et les températures employées. Face à cette situation, nous avons proposé plusieurs études préliminaires afin de déterminer les modalités d’exercice et de cryothérapie les plus appropriées pour définir un programme simple, efficace et adapté aux patients PR. Ces travaux ont été réalisés d’une part avec des sujets sains et d’autre part avec des patients PR. Nous avons également entrepris de mieux définir les conditions d’utilisation de la vitesse de propagation de l’onde de pression pour traduire la rigidité artérielle, afin d’utiliser cette dernière comme un marqueur des effets de nos propositions de programme d’EP sur le risque cardiovasculaire. Enfin nous avons tenté d’évaluer quels pouvaient être les freins à la pratique d’EP pour ces patients afin de pouvoir les prendre en compte et les contourner dans la mise en place de nos propositions. Les principaux résultats de nos travaux nous ont permis de définir les caractéristiques d’un programme d’EP associé à de la cryothérapie pour des patients PR afin d’agir sur leur rigidité artérielle.Ce programme, intitulé Prexcrim, a été mise en œuvre avec un groupe de patients atteints de PR. Les premiers résultats que nous avons obtenus confirment la faisabilité de nos propositions et la bonne tolérance des patients. Aucune sortie de l’étude ou effet secondaire a été observé. A ce stade des inclusions et de l’analyse des résultats, il semble que le programme d’EP proposé permette de modifier la rigidité artérielle en particulier des patients qui présentaient une rigidité artérielle élevée au départ. Il n’a pas été observé d’aggravation de la maladie ou du syndrome inflammatoire ce qui semble renforcer l’intérêt de la méthode de cryothérapie proposée. Les inclusions qui se poursuivent permettront sans doute d’affiner ces premières interprétations.En conclusion, notre travail a permis de combler une partie des lacunes constatées dans la littérature en termes de lutte contre le risque cardiovasculaires accru constaté chez les patients PR. Notre approche a permis la réalisation d’un programme simple et facile d’EP associé à de la cryothérapie, dont les premiers résultats répondent aux attentes fixées. Les premières analyses que nous avons réalisées montrent que les principes d’individualisation et de progressivité seront certainement à améliorer pour optimiser les effets du programme
Rheumatoid arthritis (RA) is an inflammatory, autoimmune, chronic and systemic disease with the presence of arthritis and peripheral synovitis. Another severe consequence of the disease and its treatments is the presence of early high arterial stiffness, hence a high incidence of cardiovascular problems for the subjects with RA. The practice of physical exercises (PE) is recognized as one of the most effective non-pharmacological therapies against the cardiovascular risk. However, the RA population has a low level of physical activity and PE programs are rarely offered in the therapeutic management of these patients. To overcome this problem, the association of cryotherapy to an appropriate PE program seems to be an interesting strategy. The objective of this work was to design and test a PE program associated with cryotherapy adapted to patients with RA in order to fight against the cardiovascular risk.From a systematic review, we have shown the lack of the literature in terms of PE program associated with cryotherapy for patients with RA, the lack of consensus on the methods used for both the type of PE to be proposed and the cryotherapy methods and temperatures employed. Consequently, we have proposed several preliminary studies to determine the most appropriate exercise and cryotherapy modalities for defining a simple, effective and suitable program. These works were carried out firstly in healthy subjects and after in patients with RA. We have also undertaken to better define the used conditions of the pulse wave velocity to interpret arterial stiffness and use it as a marker of effects of our PE program on cardiovascular risk. Finally, we tried to evaluate what could be the obstacles to the practice of PE for these patients, to consider and overcome them in the implementation of our proposals. The main results of our works allowed us to define the characteristics of a PE program associated with cryotherapy for patients with RA to act on their arterial stiffness.This program, entitled Prexcrim, was implemented with a group of patients with RA. The first results confirmed the feasibility of our proposals and the good tolerance of patients. No study output or side effect was observed in the patients. At this stage of inclusion and analysis of the results, it appears that the proposed PE program allows for changes in arterial stiffness, particularly for patients with high arterial stiffness. It was not observed exacerbation of the disease or inflammatory syndrome, which seems to reinforce the interest of the proposed cryotherapy method. The inclusions that continue will undoubtedly refine these first interpretations.In conclusion, our work proposes some responses about the lack in terms of the fight against the increased cardiovascular risk observed in patients with RA. Our approach allowed the realization of a simple and easy PE program associated with cryotherapy. The first results meet our expectations. The first analyzes shown that the principles of individualization and progressivity need to be improved to optimize the effects of the program
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Barani, Lonbani Zohreh. "Micro-CT based characterisation of changes to the vascular network following closed soft tissue trauma and cryotherapy." Thesis, Queensland University of Technology, 2015. https://eprints.qut.edu.au/91394/1/Zohreh%20Lonbani%20Thesis.pdf.

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This project has investigated how the architecture of the blood vessels supplying nutrients to skeletal muscles is affected by muscle contusion injuries, and how it changes during healing with or without initial treatment of the injury by icing. In order to do this, we used contrast agents to visualise blood vessels in 3D with micro-computed tomography imaging. This research significantly contributes to the fields of orthopaedics, traumatology and sports medicine, as it improves our understanding of muscle contusion injuries. Furthermore, the methods developed in this thesis may help to improve the diagnosis and monitoring of these injuries.
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28

Carneiro, Mário Brandão. "Equipamento de hipotermia para ser utilizado em tratamento muscular com lesões na fase aguda /." Guaratinguetá : [s.n.], 2010. http://hdl.handle.net/11449/97037.

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Orientador: Luiz Roberto Carrocci
Banca: João Andrade de Carvalho Junior
Banca: Valesca Alves Correa
Resumo: A idéia da realização deste trabalho e do desenvolvimento do equipamento por ele apresentado surgiu a partir da necessidade de se obter um dispositivo que substituísse a utilização do gelo no tratamento de lesões muscuesqueléticas. Esta terapia, muito utilizada desde tempos passados, vem do conceito da crioterapia, que nada mais é do que o uso do frio para diminuição da temperatura dos tecidos corporais e, conseqüentemente, o tratamento de lesões agudas. A crioterapia tem a função de reduzir a dor e o espasmo muscular e de proporcionar a vasoconstrição, evitando a contaminação dos tecidos ao seu redor. Seu objetivo principal é retirar calor corporal através do resfriamento da região lesionada de modo a influenciar na reação inflamatória aguda. A remoção do calor corporal se dá através da transferência de calor entre o equipamento e o corpo humano, ou seja, pelo o fator de condutividade térmica de cada superfície. Para obtenção de um equipamento que pudesse gerar baixa temperatura, foi abordado o estudo de dispositivos termoelétricos, sobretudo das células Peltier, que são capazes de gerar tanto baixa quanto alta temperatura. Isto se dá através da junção de dois condutores de materiais diferentes alimentados por uma tensão elétrica em circuito fechado. Baseado na necessidade de praticidade, este trabalho apresenta o estudo da crioterapia, de dispositivos termoelétricos, sob o conceito de troca de calor, propondo um equipamento de fácil manejo e serão apresentados os resultados dos testes realizados como o equipamento, suas características e vantagens
Abstract: The idea of this work carrying out and the equipment development introduced by it arose from the need to obtain a device that replaces the application of ice to treat Musculoskeletal injuries. This therapy, widely used since ancient times, comes from the concept of cryotherapy, which is nothing more than the use of cold to decrease the temperature of body tissues and, consequently, the treatment of acute injuries. Cryotherapy has the function to reduce the pain and muscle spasm and provide vasoconstriction, preventing contamination of surrounding tissues. Its main objective is to remove body heat by cooling of the injured area in order to influence the acute inflammatory reaction. The removal of body heat is through heat transfer between the equipment and the human body, ie, by the factor of thermal conductivity of each surface. To achieve a device that could generate low temperature, was approached the thermoelectric devices study, especially from the Peltier cells, which are able to generate both low as high temperature. This occurs through the junction between two conductors of different materials supplied by a voltage in a closed circuit. Based on the need of convenience, this work presents a cryotherapy study, from thermoelectric devices, under concept of heat exchange, proposing a device easy to handle and will present the results of testing the equipment, its characteristics and advantages
Mestre
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29

Anderson, Courtney Rae. "The Rate of Intramuscular Tissue Temperature Reduction Between Wetted Ice with Elastic Wrap and Game Ready®." Thesis, North Dakota State University, 2020. https://hdl.handle.net/10365/31747.

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In recent years, the Game Ready® unit has become a popular cryotherapy modality to treat musculoskeletal injuries. The purpose of this study was to determine which cryotherapy method, wetted ice bag with elastic wrap or Game Ready®, decreases triceps surae intramuscular tissue temperature the most during a 30-minute treatment. The independent variables were the cryotherapy modalities (Game Ready® and wetted ice with elastic wrap) and time (baseline, 10, 20, and 30 minutes). Twenty patients participated in this study. Wetted ice with elastic wrap decreased tissue temperatures significantly greater than Game Ready® at 20 minutes (P = 0.03), and 30 minutes (P = 0.02). Since wetted ice with elastic wrap produced a greater and faster decline in intramuscular tissue temperature compared to Game Ready® on medium pressure, this cryotherapy modality should be utilized in the immediate care phase of the injury repair process.
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30

McCrone, Michael Samuel. "The Effects of a Kinesio? Tape Application on Intramuscular Tissue Temperature Change during a 20-Minute Cryotherapy Application." Thesis, North Dakota State University, 2017. https://hdl.handle.net/10365/28591.

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The methodology for this research study was specifically designed to investigate whether or not Kinesio? Tape would act as a barrier during a cryotherapy application. Previous research has concluded that certain dressings can act as a barrier and impede the decrease in temperature in the underlying tissue. However, the properties of Kinesio? Tape are supposed to mimic the properties of skin. The thickness of Kinesio? Tape is miniscule compared to other barriers such as a plaster cast or an ace bandage. Due to this property, there were no statistically significant results found in intramuscular tissue temperature change comparing the use of the tape application and no application. This research has provided evidence-based support that the use of cryotherapy over a Kinesio? Tape application will have no adverse effects.
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31

Fornes, Manon Myriam Stephanie. "Os efeitos da imersão em água fria e da câmara de crioterapia em desportistas: revisão bibliográfica." Bachelor's thesis, [s.n.], 2018. http://hdl.handle.net/10284/6724.

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Projeto de Graduação apresentado à Universidade Fernando Pessoa como parte dos requisitos para obtenção do grau de Licenciada em Fisioterapia
Introdução: a crioterapia, nas suas diversas formas de aplicação, é uma modalidade frequentemente utilizada em ambientes clínicos e desportivos para o tratamento de lesões músculo-esqueléticas, tanto na fase aguda como durante a reabilitação. Objetivo: avaliar os efeitos da utilização da imersão em água fria e da câmara de crioterapia pós esforço, em indivíduos saudáveis ativos e/ou em desportistas.Metodologia: a pesquisa foi realizada na base de dados Pubmed, fundamentada com artigos recentes, avaliados segundo a escala Critical Appraisal Skills Programme (CASP). Resultados: Nesta revisão foram incluídos 7 estudos, com um total de 164 atletas de ambos os sexos, e com idade entre 18 e 35 anos. Após a utilização destas técnicas de crioterapia, pode-se observar redução de temperatura no músculo e no corpo, sendo mais acentuada com a câmara de crioterapia, e benefícios na recuperação muscular, perceção de dor, sensação de desconforto ou no bem-estar. A imersão em água fria, apesar de não interferir com o equilíbrio nem com o tempo de reação, dificulta a perceção posicional.Conclusão: ambas as técnicas evidenciam benefícios na recuperação muscular pós esforço, embora com certas especificidades nos seus efeitos.
Introduction: Cryotherapy, in its various forms of application, is a modality frequently used in clinical and sports environments for the treatment of musculoskeletal injuries, both acute and during rehabilitation. Objective: to evaluate the effects of the use of cold water immersion and post-effort cryotherapy chamber in active healthy individuals and / or sportsmen. Methodology: the research was carried out in the Pubmed database, based on recent articles evaluated according to scale Critical Appraisal Skills Program (CASP). Results: In this review, 7 studies were included, with a total of 164 athletes of both sexes, and aged between 18 and 35 years. After using these cryotherapy techniques, it can be observed a reduction in temperature in the muscle and in the body, being more accentuated with the cryotherapy chamber, and benefits in muscle recovery, pain perception, discomfort sensation or well-being. The immersion in cold water, although not interfering with the balance nor with the reaction time, hinders the positional perception. Conclusion: both techniques show benefits in muscle recovery after exertion, although with certain specificities in their effects.
N/A
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32

Ahmed, Shwan. "Cryotherapy of the prostate : Assessment of and correlation between iceballs thermal properties and quality of life after salvage treatment." Thesis, University of Surrey, 2008. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.502666.

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33

Hawkins, Jeremy R. "The Treatment Effect of Cryotherapy, Compression, A Tobacco Poultice, and the PolyMem SportsWrap R on an Experimentally Induced Bruise." BYU ScholarsArchive, 2009. https://scholarsarchive.byu.edu/etd/1990.

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Context: It is common practice to treat musculoskeletal injury acutely with cryotherapy with compression. A tobacco poultice and the SportsWrap are touted as effective acute care treatments, yet are unproven. Objective: Compare four treatments (cryotherapy with compression, compression alone, a tobacco poultice, and the SportsWrap) of an experimentally induced bruise to determine their effectiveness at limiting bruise formation, thereby decreasing overall bruise duration. Design: Randomized, controlled, blinded trial. Setting: Research laboratory. Participants: 64 male participants (height: 180.2±6.4cm, weight: 78.0±16.2kg, age: 22.1±2.8yrs) volunteered. Participants committed to not exercise during participation and were free of medication affecting coagulation or inflammation at least 3 days before and throughout the study. Interventions: Participants were shot in both quadriceps with a tennis ball fired from a tennis ball machine at ~31m/sec from 46cm. Digital pictures were taken of the trauma site immediately before and on days 2, 4, 6, 8, and 10 post-trauma. Within 5 minutes of being shot, participants were randomly assigned to receive 1 of 4 treatments to one of their legs: 1) cryotherapy with compression (applied 5 times separated by 2 hours, compression applied with and without the ice until return on Day 2); 2) compression alone (worn continuously until Day 2); 3) a tobacco poultice (worn for no less than 12 hours, then removed; compression reapplied until Day 2); and 4) the SportsWrap (worn continuously until Day 2). Treatment times reflected clinical practice. Untreated leg served as control. Two raters, blinded to treatment and treatment leg, analyzed each bruise, while a third analyzed an unbruised control area for normalization. Software calculated average pixel values of cyan, magenta, yellow, black, and luminosity for each picture. This analysis was shown to be reliable during pilot data collection (ICC = .77) and has been used previously. Main Outcome Measures: Color difference, a unitless value, was calculated as the difference between the treatment and control legs from the normalized average pixel values. A 2 x 4 x 6 mixed model ANOVA followed by Bonferroni post hoc analysis determined differences between limbs and treatments over time. Results: There was no treatment (F3,60 = .47, P = .70) or limb (F1,60 = .04, P = .84) effect, but there was a day effect (F3.9,234.5 = 6.82, P < .001). The mean color difference values were greater on Days 4 and 6 than Days 0 and 10, and Day 4 was greater than Day 2 (Bonferroni < .05). None of the interactions were significant. Conclusions: Treatment had no effect on the degree of bruising that we produced in this study. We are reluctant to generalize this data to musculoskeletal injury beyond what we caused because of insufficient bruising/too great of variance in bruising.
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34

Bastos, Fábio do Nascimento [UNESP]. "Influência de diferentes tipos de recuperação sobre a modulação autonômica cardíaca, concentração de lactato e proteína C-reativa." Universidade Estadual Paulista (UNESP), 2010. http://hdl.handle.net/11449/87295.

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Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)
A recuperação pós-exercício consiste em restaurar os sistemas do corpo à sua condição basal, proporcionando equilíbrio e prevenindo a instalação de lesões e, nesse sentido, torna-se aspecto importante de todo programa de condicionamento físico, em quaisquer níveis de desempenho, mas, sobretudo nos mais elevados. O objetivo desta revisão foi reunir informações e descrever as respostas proporcionadas por métodos recuperativos pós-exercício como, crioterapia, contraste, massagem e recuperação ativa, constituindo uma fonte de atualização do referido tema. Utilizou-se os bancos de dados, MedLine, Scielo e Lilacs, como lista de periódicos o SportsDiscus. Foram incluídos no estudo somente ensaios clínicos randomizados controlados e não-controlados além de artigos...
The post-exercise recovery consists in restoring the body systems to baseline condition, providing balance and preventing injuries installation and, in that sense; it becomes an important aspect of every fitness program, at any levels of performance, but especially in higher levels. The objective of this review was to gather information and to describe the responses provided by post-exercise recovery methods, such as cryotherapy, contrast water immersion, massage and active recovery, providing an update on this issue. MedLine, Scielo and Lilacs databases were used, as well as the SportsDiscus list of journals. Only randomized controlled and non-controlled clinical essays, in addition to review articles concerning the proposed topic were included. Our choice was for the search terms: cryotherapy, massage, active recovery, thermotherapy, immersion and exercise, individually and combined. It was observed that some studies report that cryotherapy is harmful concerning post-exercise recovery, once it reduces performance immediately after the technique... (Complete abstract click electronic access below)
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Takasaka, Iuuki 1980. "Ensaio clínico aleatorizado de crioterapia intra-operatória versus fotocoagulação pós-operatória a laser para retinopexia na cirurgia de introflexão escleral." [s.n.], 2012. http://repositorio.unicamp.br/jspui/handle/REPOSIP/311824.

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Orientadores: Rodrigo Pessoa Cavalcanti Lira, Carlos Eduardo Leite Arieta
Dissertação (mestrado) - Universidade Estadual de Campinas, Faculdade de Ciências Médicas
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Resumo: Introdução: O descolamento de retina regmatogênico (DRR), uma das causas de cegueira, tem uma incidência anual de cerca de 6,3 - 17,9/100.000 habitantes na população mundial, e se não tratado pode levar a cegueira devido a degeneração das camadas retinianas. O uso de introflexão em conjunto com as adesões coriorretinianas em torno da rotura retiniana forma a base do tratamento para muitos DRR simples. A crioterapia realizada para retinopexia intra-operatoria tem sido implicada no desenvolvimento de pucker macular e vitreorretinopatia proliferativa. Eliminar a crioterapia da cirurgia convencional de introflexão poderia não afetar o resultado do sucesso anatômico e melhorar a recuperação visual. Objetivo: O objetivo primário deste ensaio clínico randomizado foi comparar a taxa de reaplicação retiniana e secundariamente os resultados da acuidade visual em pacientes com DRR que se submeteram a cirurgia de introflexão escleral e retinopexia com a crioterapia intra-operatória versus fotocoagulação a laser pós-operatório (um mês após a cirurgia). Método: É um ensaio clínico aleatorizado, mascarado, realizado em um único centro, composto por 86 pacientes submetidos à cirurgia de introflexão escleral. Os pacientes foram aleatorizados para serem submetidos à cirurgia de introflexão escleral e retinopexia com crioterapia intraoperatória (criopexia) ou retinopexia com fotocoagulação a laser pós operatória de 30 dias (laserpexia) após o procedimento. O desfecho primário foi avaliar a taxa de reaplicação retiniana no seguimento pós-operatório em 1 semana. Os desfechos secundários foram avaliar as taxas de reaplicação retiniana, as taxas de reoperação, as taxas de complicações pós-operatórias e recuperação da acuidade visual, em 1 mês e 6 meses de seguimento pós-operatório. Resultados: Foram incluídos 86 olhos de 86 pacientes a serem submetidos introflexão escleral. A amostra foi constituída de 43 pacientes pertencentes ao grupo laserpexia e 43 pacientes atribuídos ao grupo criopexia. Os dados demográficos foram semelhantes nos dois grupos. A taxa de sucesso anatômico em 1 semana, 1 mês e 6 meses foram semelhantes nos dois grupos, respectivamente, 93% (40 pacientes), 100% e 100% no grupo criopexia e 95,3% (41 pacientes), 100% e 100% no grupo da laserpexia (P, respectivamente, 0,5; 1,0 e 1,0). Três pacientes do grupo criopexia e 2 do laserpexia foram submetidos a uma cirurgia adicional (vitrectomia via pars plana) após a falha primária em 1 semana de seguimento. As complicações pós-operatórias foram semelhantes nos dois grupos, com exceção do edema de pálpebras. A recuperação visual foi mais lenta no grupo da crioterapia. A diferença na AV após 6 meses não foi significativa. Conclusão: Em pacientes com descolamento de retina regmatogênico sem complicações, ambas as técnicas de retinopexia mostraram resultados anatômico e funcional satisfatórios. A opção por laserpexia oferece recuperação visual mais rápida com menos complicações, porém requer uma segunda intervenção e maior custo em relação a criopexia
Abstract: Introduction: Rhegmatogenous retinal detachment (RRD), one of causes of blindness, has an annual incidence of about 6.3 to 17.9/100.000 people in the world population, and if untreated can lead to blindness due to degeneration of the retinal layers. The use of scleral buckles combined with chorioretinal adhesions around the retinal tear forms the basis of treatment for many simple RRD. Cryotherapy for retinopexy performed intraoperatively has been implicated in the development of macular pucker and proliferative vitreoretinopathy. Eliminating cryotherapy of conventional surgery might not affect the outcome of anatomic success and improve visual recovery. Objective: The aim of this randomized clinical trial was to compare the rate of retinal reapplication and secondly the results of visual acuity in patients with rhegmatogenuos retinal detachment who underwent surgery with scleral buckle retinopexy and intraoperative cryotherapy versus laser photocoagulation postoperatively (one month after surgery). Method: A randomized, masked, performed in a single center, comprising 86 patients undergoing scleral buckle surgery. Patients were randomized to undergo surgery, scleral buckle retinopexy with cryotherapy and intraoperative (criopexy) or postoperative retinopexy with photocoagulation 30 days (laserpexy) after the procedure. The primary endpoint was to evaluate the rate of replication in retinal postoperative follow-up within 1 week. Secondary endpoints were to evaluate retinal reapplication rates, reoperation rates, rates of postoperative complications and recovery of visual acuity at 1 month and 6 months postoperative follow-up. Results: We included 86 eyes of 86 patients undergoing scleral buckle. The sample consisted of 43 patients belonging to the group laserpexy and 43 patients assigned to the group criopexy. Demographic data were similar in both groups. The anatomic success rate in 1 week, 1 month and 6 months were similar in both groups, respectively, 93% (40 patients), 100% and 100% in criopexy and 95.3% (41 patients), and 100% 100% in group laserpexy (P, respectively, 0.5, 1.0 and 1.0). Three patients of group criopexy and 2 of laserpexy underwent additional surgery (pars plana vitrectomy) after the primary failure at 1-week follow-up. The postoperative complications were similar in both groups, except for edema of the eyelids. The visual recovery was slower in the cryotherapy group. The difference in VA after 6 months was not significant. Conclusion: In patients with uncomplicated rhegmatogenuos retinal detachment, both techniques of retinopexy showed satisfactory anatomical and functional results. The choice of laserpexy offers faster visual recovery with fewer complications, but requires a second intervention and higher cost compared to criopexy
Mestrado
Oftalmologia
Mestre em Ciências Médicas
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36

Perrier, Julie. "Estudo do conhecimento dos fisioterapeutas e alunos de fisioterapia acerca da aplicação de crioterapia no tratamento das entorses de tornozelo." Bachelor's thesis, [s.n.], 2020. http://hdl.handle.net/10284/9292.

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Projeto de Graduação apresentado à Universidade Fernando Pessoa como parte dos requisitos para obtenção do grau de Licenciada em Fisioterapia
Introdução: A compreensão dos mecanismos fisiológicos da cicatrização e dos efeitos do frio evita efeitos deletérios sobre o tecido. Objetivo: O objetivo deste estudo é avaliar o conhecimento de fisioterapeutas e alunos de fisioterapia sobre a aplicação da crioterapia no tratamento de lesões traumáticas no tornozelo . Metodologia: 195 participantes de ambos os sexos foram incluídos, com 127 fisioterapeutas e 68 alunos de fisioterapia. A idade média dos participantes é de 29,75±7,65 ano. Foi seguido o método Delphy para a construção do questionário, utilizando a melhor evidência disponível acerca da temática para formular as 20 perguntas. O conhecimento foi medido por uma escala de avaliação portuguesa de 0 a 20. Resultados: Os participantes obtiveram uma média de 14,17±2,34 no score ao questionário. As médias das notas segundo a situação profissional (p=0,381), o ano escolar (p=0,839) e a experiência profissional (p=0,816) não apresentam diferenças, sendo que os participantes com ausência de formação profissional têm uma média mais baixa (p=0,008). Na análise do score por questão nota-se diferenças significativas quanto à situação profissional nas questões 14, 16 e 19. Conclusão: Os participantes têm a menção “Bom com distinção” sobre conhecimento do uso da crioterapia.
Introduction : Understanding the physiological mechanisms of healing and the effects of cold avoids harmful effects. Objective : The aim of this study is to evaluate the knowledge of physiotherapists and physiotherapy students on the application of cryotherapy in the treatment of traumatic ankle injuries. Methodology: 195 participants of both sexes were included, with 127 physical therapists and 68 students from several years of physiotherapy course. The average age of the participants is 29.75±7.65 years. We followed the Delphy method to build the questionnaire and used articles to formulate the 20 questions. Knowledge was measured by a Portuguese rating scale from 0 to 20. Results: The participants had an average of 14.17±2.34. Average grades according to professional status (p=0,381), school year (p=0,839) and professional experience (p=0,839) do not differ and participants with no professional training have a lower average (p=0,008). In the individual analysis of the score per question, it is noted significant differences regarding the professional situation in questions 14, 16 and 19. Conclusion : Participants have the mention “Bom com distinção” about knowledge of the use of cryotherapy.
N/A
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37

Stievani, Fernanda de Castro. "Desenvolvimento de protocolo de reabilitação no período pós-operatório inicial de artroscopia em equinos." Universidade de São Paulo, 2014. http://www.teses.usp.br/teses/disponiveis/10/10137/tde-05012015-145247/.

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O presente estudo teve por objetivo avaliar protocolo de reabilitação para o período pós-operatório inicial de artroscopias visando diminuir a inflamação no local operado e aumentar a mobilidade articular. Foram utilizados 12 equinos (total de 20 articulações) encaminhados para artroscopia com diagnóstico de osteocondrite dissecante. Dessas, dez articulações receberam protocolo de reabilitação nos primeiros cinco dias do período pós-operatório. O protocolo consistiu em crioterapia, movimentação passiva da articulação e exercício controlado de baixa intensidade, além de uso sistêmico de anti-inflamatório. O outro grupo, também composto por dez articulações, recebeu apenas a terapia utilizada rotineiramente no HOVET-USP, consistido de repouso em baia e antiinflamatório. As articulações foram avaliadas quanto à circunferência em centímetros, ângulo de flexão, termografia, grau de claudicação. Amostras de líquido sinovial foram coletadas imediatamente antes do procedimento cirúrgico (D1), após 48h (D3) e após 96h (D5) para análise física, qualidade do coágulo de mucina, e quantificação de biomarcadores (IL-1, IL-6 e IL-10, PGE2 e SAA). As análises de exame de claudicação, circunferência articular, ângulo de flexão articular e termografia não apresentaram diferenças significativas entre os grupos, nem entre os diferentes dias do mesmo grupo. Na análise do líquido sinovial, a cor e o aspecto apresentaram piora do D1 para o D3, de amarelo claro para avermelhado e de límpido para turvo, respectivamente, nos dois grupos. No entanto, no grupo tratado houve melhora do D3 para o D5, tanto para cor (de avermelhado para maioria xantocrômica e amarela) como aspecto (de maioria turva para ligeiramente turva). No grupo controle os líquidos permaneceram sem alteração em cor e aspecto de D3 para D5, e nas comparações entre os grupos não houve diferença para D1, D3 e D5. A viscosidade do líquido sinovial no grupo controle diminuiu significativamente quando comparados D1, D3 e D5. Já no grupo tratado a diminuição da viscosidade só foi observada quando comparados D1 e D5. O coágulo de mucina apresentou piora de D1 para D3 no grupo controle, com elevação não significativa de D3 para D5, enquanto que para o grupo tratado não houve diferença significativa de D1 para D3 e de D3 para D5, quando comparados o D5 dos dois grupos, o tratado obteve melhor qualidade. As concentrações de interleucina nas amostras não forneceram dados suficientes para análise. Na análise das concentrações de PGE2 não houve diferença entre os grupos nos diferentes momentos, ocorrendo elevação de D3 para D5 em ambos os grupos, porém, no grupo tratado não há diferença entre D1 e D5. Já para SAA os grupos apresentaram comportamento similar de resposta, com elevação de D1 para D3 e queda de D3 para D5, porém menos acentuado no grupo tratado, o que levou a diferença entre os grupos em D3. Pode-se concluir, que o protocolo de reabilitação, apesar de não gerar diferença significativa para as avaliações de exame físico dos animais, proporcionou melhor qualidade de líquido sinovial quanto a cor, aspecto, viscosidade e precipitado de mucina, além de evidenciar menores elevações nas concentrações de marcadores inflamatórios no liquido sinovial durante o período estudado.
The purpose of this study was to evaluate a rehabilitation protocol for the initial postoperative period of metatarsophalangeal, metacarpophalangeal and tarsocrural´s arthroscopies, which seeks to, minimize local inflammation, diminish swelling, promote better joint range of motion and pain relief during such period. Twelve horses participated in this study - amounting to 20 joints - with dissecans ostheochondritis diagnosis. The first group was formed by ten joints, which were treated under rehabilitation protocol for the first 5 days as from the surgery (Treated group). The rehabilitation protocol consisted of cryotherapy, passive range of motion, low intensity exercise and non-steroidal anti-inflammatory drug. The second group also formed of ten joints received the standard HOVET-USP therapy, which consists of rest and non-steroidal anti-inflammatory drug Both groups were treated with the same non-steroidal anti-inflammatory drugs. The joints were measured for circumference, maximal flexion angle, thermography, and lameness score on the day before the surgery (D0) and during the first four days after the surgery. Synovial fluid samples were collected immediately before surgery (D1), within 48 hours (D3), and within 96 hours from the surgery (D5). The analysis evaluated gross appearance (color and aspect), viscosity and mucin clot quality, as well as biomarkers (Il-1, Il-6, Il- 10, PGE2, and SAA) quantification. Lameness examination, joint circumference, flexion angle and thermography evaluation were not significantly different between groups. In synovial fluid analyses de color and aspect have worsen from D1 (clear light yellow) to D3 (turbid hemorrhagic) in both groups. On treated group color and aspect improved from D3 (turbid hemorrhagic) to D5 (xanthochromic and yellow slightly turbid). On treated group there was no difference between D3 and D5. When the groups were compared, none significant differences was seen. The fluid viscosity of control group had significant decrease from D1, to D3 and from D1 and D5. In treated group this viscosity decrease was only seen between D1 and D5. The mucin clot formation worsened when D1 e D3 of control group was compared and remains similar from D3 to D5. In treatment group there were no differences when compared D1 with D3 and D3 with D5. The comparison between groups of D5 has shown treated group improved clot. The interleukin couldn´t be measured on sufficient number of samples for the statistics method. There were no differences between groups on all moments. The PGE2 response was similar in both group with a rise on concentration from D3 to D5. In treated group D1 was similar to D5. This results suggests more evident inflammatory response in the control group. For the SAA the groups have shown similar responses, with an increase from D1 to D3 and decrease from D3 to D5. The response on treated group was less intense and demonstrates lower values in D3 when compared with D3 control group. It was concluded with this study that rehabilitation protocol improved synovial fluid analyses for, color, aspect, viscosity and mucin clot. It even had promoted lower concentrations of inflammatory biomarkers for the treated group during the period.
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Lui, Pui-ling, and 呂佩玲. "Evidence-based guidelines of using cryotherapy in reducing pain, knee swelling and improving range of motion for patients after total kneereplacement." Thesis, The University of Hong Kong (Pokfulam, Hong Kong), 2012. http://hub.hku.hk/bib/B48335939.

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Introduction: Knee osteoarthritis is one of the common causes leading to musculoskeletal disability of the elderly around the world. Total knee replacement (TKR) is an effective and common treatment for end stage knee arthritis. Most papers suggest that early rehabilitation could improve postoperative knee function. However, postoperative pain and local swelling are the complications that diminish range of motion (ROM) and inhibit patients’ recovery. A comprehensive review of the literature reveals that cryotherapy is an effective and safe method to overcome these complications. In this paper, a guideline of using cryotherapy in reducing postoperative pain and knee swelling so as to improve the ROM of patients and promote recovery after TKR has been developed. Objectives: The objectives of this translational research are: (1) to look for relevant papers that related to cryotherapy in reducing postoperative pain and knee swelling so as to improve the ROM of patients after TKR; (2) to gather and criticize the data obtained; (3) to develop a guideline of using cryotherapy in reducing pain, knee swelling and improving ROM of patients after TKR based on the evidence from the reviewed literature; (4) to assess the implementation potential of the newly developed guidelines; and (5) to establish the implementation and evaluation plans for the new innovation. Methods: An empirical literature search published from 2001 to 2011 by several searching engines regarding cryotherapy in reducing postoperative pain and knee swelling with the aim to improve the ROM of patients after TKR has been conducted. After that, the qualities of relevant studies were retrieved and criticized by using the appraisal checklist of the SIGN (2004). The derived evidences were then be summarized and synthesized. An evidence-based guideline was established with reference to the evidence from the reviewed literatures and the results of the quality assessment. Recommendations are graded by SIGN (2004). The implementation potential including transferability, feasibility and cost-benefit ratio of the innovation were assessed as well. Lastly, implementation and evaluation plans have been developed to assess and appraise the effectiveness of the new guideline. Results: Finally, seven studies were chosen as final references after methodological quality assessment. Four main types of comparison were made from these seven reviews including: (1) continuous compressive cryotherapy vs. compressive crepe bandage; (2) comparison in different temperature of cryotherapy; (3) outcome measures; and (4) complications in cryotherapy. After the summary, six main categories of recommendations were synthesized: (1) continuous compression cryotherapy; (2) effective temperature; (3) potential complications; (4) regular assessment; (5) duration; and (6) intermitted ice pack regimen. Based on these syntheses and recommendations, a guideline of using cryotherapy for patients after having TKR was developed. Conclusion: With the implementation of the newly developed evidence-based cryotherapy guidelines for patients after having TKR in local clinical settings, the improvement in the ROM of the knee joint will be anticipated as a result of the reduction in postoperative pain and knee swelling.
published_or_final_version
Nursing Studies
Master
Master of Nursing
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39

Svanberg, Anncarin. "Mucositis Prevention for Patients Receiving High Dose Chemotherapy and Stem Cell Transplantation : Preventive Strategies - There is Always More to do." Doctoral thesis, Uppsala universitet, Hematologi, 2012. http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-179508.

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The aim of this thesis was to investigate oral cryotherapy (OC) as prophy-laxis against oral mucositis (OM) in patients given high-dose chemotherapy for stem cell transplantation (SCT). A new mouth rinse device was tested for possible additive effect to OC. For study I-III, 78 patients were randomised to OC or standard oral care (SOC). Papers I and II showed that OC patients had significantly less severe mucositis, pain, opioid use, lower C-reactive protein and less parenteral nutrition treatment (TPN). There was no difference in relapse rate, and 5-year survival was unexpectedly significantly better in the OC group (Paper III). In paper IV, the local effect of OC on the mucosa of the mouth was investigated by the use of an infrared thermograph. Change in surface temperature in eight areas of the mouth cavity was measured after cooling of the mouth in healthy volunteers. A substantial lowering of the temperature (-12.9 °C, mean) was seen which could explain the efficacy of OC. To exclude that acute cooling in itself is traumatic, the proinflammatory cytokine IL-6 was measured in saliva and showed no increase after cooling. Paper V reported a study in 40 allogeneic SCT patients. 20 were given SOC including OC and 20 in addition received Caphosol®, a calcium phosphate mouth rinse, during chemotherapy and until day 21. Severity of mucositis, use of opioids and TPN, effects on nutrition and CRP levels were measured. No significant difference was found between the groups in any of these variables, but a non-significant trend for an advantage for the combination could be seen. IL-6 saliva levels were measured. There was a substantial increase (more than 10-fold), in mean IL-6 levels from baseline to beginning of mucositis and a weak correlation between increased IL-6 levels and severity of OM, suggesting that IL-6 in saliva may be a useful marker of the inflammatory mucosal process. This thesis demonstrates that OC is effective as prophylaxis against chemotherapy-induced OM. As a consequence of this work, OC has been introduced as the standard of care in all SCT patients in our institution.
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40

Berger, Justina. "Krioterapijos poveikis kelio sąnario funkcijoms po kryžminių raiščių plastikos." Master's thesis, Lithuanian Academic Libraries Network (LABT), 2006. http://vddb.library.lt/obj/LT-eLABa-0001:E.02~2006~D_20060510_114811-86104.

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Problem of research. Joints – important part of human movement apparatus. Therefore joint traumas are a serious problem both from medical and social point of view. In case of mechanical trauma very often knee joint is hurt. Most often young people suffer from traumas, particularly sportsmen when knee joint cruciate ligaments are hurt. In such situations as one of the most effective physioterapical treatment methods cryotherapy is applied. In 2004 in Lithuania particularly low temperature medical CO2 gas (-78 0C) was applied, sprinkled with 50 bar power. Dry bacteriostatic gas which during a very short time of application (30–60 sec) cause thermal shock in tissues – cool down tissues in a very short time from +5 to +2 0C. Theoretical background of cryotherapy and practical experience in Lithuania are not widely described that’s why it is necessary to make more intense research, to generalize its results, to seek for most effective methods of research stimulating faster rehabilitation of patients’ working capacity. Objective of study. Taking into consideration the fact that cryotherapy is very new and very live in Lithuania, it was selected as the theme for Master’s thesis, its objective is to estimate the influence of cryotherapic treatment on the functions of knee joint functions after cruciate ligament reconstruction. Task of study: to evaluate the dynamics of pain intensity experienced by patients, knee joint movement amplitude dynamics, knee joint oedema scope dynamics... [to full text]
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Orlandini, Jacque. "Die effek van krioterapie op die akute herstel van universiteit-netbalspelers se onderbeenspiere / Jacque Orlandini." Thesis, North-West University, 2007. http://hdl.handle.net/10394/1829.

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In the last few years researchers have more and more focussed on the possible use of cryotherapy as an acute and long term recovery facilitating technique by sportsmen and women. Barnette (2006) did, however, state that research supporting cryotherapy as a recovery facilitating technique, is not convincing and that the majority of research show that it has a negative impact on the recovery of subjects after exercise. It is against this background that the aim of the study was firstly to critically analyse the available literature of the past fifteen years (1992-2007) with regard to the study subject; die nature of the cryotherapy technique that was used as well as the findings with regards to the effects of these types of techniques on a wide variety of physiological variables, physical and motor performance; secondly, to provide guidelines for the use of cryotherapy as a recovery facilitating technique and thirdly to determine the effect of cryotherapy on the acute recovery of University netball players' lower leg muscles in an isokinetic ankle exercise. Firstly, it was shown that ice water immersion and ice pack application are the most common techniques that are used in cryotherapy studies. The results in the majority of articles indicated that cryotherapy had a non-significant acute effect on isokinetic, eccentric and concentric peak torque as well as time to reach peak torque and the angle at which the peak torque was reached; isometric, maximal and sub-maximal strength and accuracy of strength execution; normalized, average vertical ground reaction force as well as time of reaching peak power and vertical jump height; baseball pitching accuracy, proprioception, ankle joint range of movement, positioning and speed during execution of a movement; blood lactate removal and blood flow speed as well as muscle soreness after completion of an exercise. With regard to the long term effects of cryotherapy research showed that isotonic hand grip strength and endurance, plasma adrenaline, non-adrenaline, dopamine, renine, aldosterone, heart rate and blood pressure after 6 weeks; respiratory gas exchange ratio, heart rate, muscle glycogen concentration, plasma lactate, glucose and free fatty acids after 8 weeks or brachial artery cross-section and vascular endothelial growth factor after 4 weeks of exercise and cryotherapy did not experience any significant changes between the cryotherapy and control group. Other physical, motor performance and physiological variables did not show a certain trend with regards to the way they were affected by cryotherapy. In some cases variables were affected significantly negatively while the opposite was true in other cases where variables were significantly positively influenced. With regard to the results of the study on the acute recovery of University netball players' lower leg muscles due to cryotherapy, it was found that the acute recovery of only four isokinetic variables were significantly influenced (p = 0.05) by cryotherapy, namely: left leg relative total dorsiflexion work, average peak dorsiflexion torque, right dorsiflexion and plantar flexion endurance. The acute recovery of the first mentioned strength endurance related variable was significantly negatively influenced by the cryotherapy. In contrast with this result the acute recovery of the three last mentioned isokinetic muscle relative peak torque and endurance related variables were significantly positively influenced by the cryotherapy. The overall conclusion that can therefore be drawn from the above-mentioned results show that the majority of isokinetic plantar- and dorsiflexion torque variables (12 out of 16, 75%) as well as other physical, motor performance and physiological variables experience no significant effect with regards to acute and long term recovery due to cryotherapy. The research did, however, show that the effectiveness of cryotherapy was influenced by the adiposity thickness, nature of the cryotherapy application, type of medium that was used for cryotherapy application and the length of time during which cryotherapy was applied. The recommendation for the use of cryotherapy as a recovery facilitating technique can be summarised as follows: the temperature of the cryotherapy medium that is used, must vary between 5°C and 10°C; the duration of cryotherapy between 15 and 20 minutes; the most general application area: for ice water immersion - immersed up until the level of the gluteal fold or crista ileac and the whole arm or forearm; for ice pack application - on the thigh, ankle and peripheral of the shoulder; the most common and effective ice pack application is direct on the skin surface by means of a bag filled with between 500 g and 1 500 g cubic formed ice. For long term use more that 2 consecutive days of cryotherapy application is recommended.
Thesis (M.A. (Human Movement Science))--North-West University, Potchefstroom Campus, 2008.
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Beleza, Ana Carolina Sartorato. "A dor perineal no pós-parto normal com episiotomia: mensuração, caracterização e efeitos da crioterapia." Universidade de São Paulo, 2008. http://www.teses.usp.br/teses/disponiveis/22/22133/tde-06102008-144024/.

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A dor perineal no pós-parto é uma das morbidades mais comuns que acometem as mulheres no período puerperal. Recursos farmacológicos e não farmacológicos têm sido investigados para aliviar tal sintoma. A crioterapia é uma técnica frequentemente utilizada na clínicaobstétrica, porém existem poucos estudos que fundamentam tal terapêutica. Diante disso, este estudo teve como objetivo geral avaliar o efeito da crioterapia no alívio da dor da região perineal em primíparas submetidas ao parto normal com episiotomia. Os objetivos específicos foram: mensurar a dor perineal em primíparas submetidas ao parto normal com episiotomia por meio instrumento unidimensional de dor, caracterizar a dor perineal por meio de instrumento de avaliação multidimensional de dor, verificar quais atividades realizadas pelas puérperas dentro da maternidade estavam limitadas pela presença da dor, verificar o efeito da crioterapia no alívio da dor imediatamente após a aplicação e uma hora pós-tratamento, verificar a temperatura da região perineal antes, durante e depois da crioterapia e a correlação com a intensidade da dor, verificar possíveis efeitos adversos provocados pela crioterapia e verificar a opinião das puérperas sobre o tratamento. Trata-se de um estudo do tipo ensaio clínico aleatório e controlado realizado em uma maternidade localizada no interior do estado de São Paulo. Foram selecionadas aleatoriamente 50 mulheres primíparas que apresentavam dor perineal após o parto vaginal com episiotomia, divididas em 26 mulheres no grupo controle e 24 no grupo experimental. Foi utilizado um formulário para a coleta de dados sócio-demográficos, sobre a assistência ao parto e os dados do recém-nascido; para avaliar a dor foi utilizada a escala numérica compartimentada em 11 pontos e os descritores do questionário McGill; também foi utilizado um formulário sobre as atividades funcionais desempenhadas pelas puérperas que estavam limitadas pela dor; por fim, foi aplicado um questionário sobre a opinião das mulheres sobre a terapêutica. A técnica de crioterapia utilizada consistiu de bolsa plástica no formato de um absorvente, contendo gelo triturado, aplicada durante 20 minutos. Foram realizadas três avaliações em ambos os grupos: avaliação inicial onde era questionada a intensidade da dor pela escala numérica e a aplicação do questionário McGill; avaliação dois: realizada após 20 minutos da primeira avaliação, sendo que no grupo experimental foi realizada após a crioterapia; avaliação três: realizada após uma hora da segunda avaliação. Este trabalho foi aprovado pelo Comitê de Ética da EERP/USP. Verificou-se alívio da dor para o grupo experimental comparado ao controle na segunda avaliação e na terceira avaliação (p=0,000). As puérperas de ambos os grupos apresentavam limitadas as funções de sentar, deitar e deambular. A dor perineal foi caracterizada pelas puérperas como latejante, que repuxa, que esquenta, ardida, dolorida, chata, incômoda, que prende e que deixa tenso. A média da temperatura perineal antes da crioterapia foi a 34,5o C, baixando para 23,4ºC após a técnica. Uma hora após o tratamento a média passou para 33,7ºC. Foi encontrada correlação positiva entre a intensidade da dor e as modificações da temperatura perineal. Sobre a satisfação das mulheres com a crioterapia 87,5% referiram estar satisfeitas com o recurso e 12,5% referiram estar muito satisfeitas. A crioterapia mostrou-se eficaz no alívio da dor perineal, entretanto, são necessários demais estudos que possam elucidar questões tais como tempo de alívio do sintoma, intervalo entre as aplicações e os efeitos sobre demais sinais e sintomas do processo inflamatório.
Postpartum perineal pain is among the most common morbidities affecting women in the puerperal period. Studies have been conducted to assess the effectiveness of pharmacological and non-pharmacological resources to relief this symptom. Cryotherapy is a frequently used clinical-obstetric technique, but few studies have provided the foundations of this therapeutics. In this view, this study had the purpose to: assess the effect of cryotherapy in providing pain relief of the perinal region of primiparae submitted to natural childbirth with episiotomy using a one-dimensional pain instrument; characterize perineal pain using a multidimensional pain assessment tool, verify what activities performed by the puerperae in the maternity were limited due to the presence of pain; verify the effect of cryotherapy in relieving pain immediately after it application, and one hour later; verify the temperature of the perineal region before, during, and after cryotherapy, and the correlation with the intensity of pain, verify the possible adverse effects caused by cryotherapy; and verify the puerperaes opinion about the treatment. This is a controlled and random clinical trial carried out in a maternity in the interior of Sao Paulo state, and it was approved by the EERP/USP Research Ethics Committee. Fifty primiparae with perineal pain after vaginal delivery with episiotomy were randomly selected and 26 were assigned to the control group and 24 to the experimental group. A form was used to collect socio-demographic data, as well as information about care during the delivery and regarding the newborn; an 11-point numerical scale and descriptors from the McGill questionnaire were used to assess the pain. In addition, a form was used to assess the functional activities performed by the puerperae that were limited due to the pain. Finally, a questionnaire was applied to obtain the womens opinion about the therapy. The cryotherapy technique used consisted of a plastic bag in the shape of an absorbent pad, containing ground ice, which was applied for 20 minutes. Three assessments were performed in both groups: an initial assessment, in which the women were asked about the intensity of the pain using the numerical scale and by administering the McGill questionnaire. The second assessment was performed 20 minutes after the first, and in the experimental group it was performed after the cryotherapy. The third assessment was performed one hour after the second. This study was approved by the EERP/USP Ethics Committee. It was verified there was pain relief in the experimental group compared to control in the second and third assessment (p=0.000). On the other hand, the women reported feeling pain again in the third assessment. The puerperae from both groups had limited functions when sitting, laying down, and walking. The puerperae characterized the perineal pain as pulsing, pulling, hot, stinging, hurting, annoying, troublesome, tight and tense. The average perineal temperature before cryotherapy was 34.5 o C, dropping to 23.4 o C after the technique. One hour after the treatment, the average lowered to 33.7 o C. There was a positive correlation between the intensity of pain and the changes in perineal temperature. As for the womens satisfaction toward the cryotherapy, 87.5% reported being satisfied with the resource and 12.5% reported being much satisfied. Cryotherapy was effective in relieving perineal pain, however further studies are needed in order to elucidate issues like time of symptom relief, interval time between applications, and the effects over other signs and symptoms of the inflammatory process.
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Cremer, Miriam, Proma Paul, Katie Bergman, Michael Haas, Mauricio Maza, Albert Zevallos, Miguel Ossandon, Jillian D. Garai, and Jennifer L. Winkler. "A Non-Gas-Based Cryotherapy System for the Treatment of Cervical Intraepithelial Neoplasia: A Mixed-Methods Approach for Initial Development and Testing." US AGENCY INT DEVELOPMENT-USAID, 2017. http://hdl.handle.net/10150/624357.

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Background: Gas-based cryotherapy is the most widely used treatment strategy for cervical intraepithelial neoplasia (CIN) in low-resource settings, but reliance on gas presents challenges in low-and middle-income countries (LMICs). Our team adapted the original CryoPen Cryosurgical System, a cryotherapy device that does not require compressed gas and is powered by electricity, for use in LMICs. Methods: A mixed-methods approach was used involving both qualitative and quantitative methods. First, we used a user-centered design approach to identify priority features of the adapted device. U.S.-based and global potential users of the adapted CryoPen participated in discussion groups and a card sorting activity to rank 7 features of the adapted CryoPen: cost, durability, efficacy and safety, maintenance, no need for electricity, patient throughput, and portability. Mean and median rankings, overall rankings, and summary rankings by discussion group were generated. In addition, results of several quantitative tests were analyzed including bench testing to determine tip temperature and heat extraction capabilities; a pathology review of CIN grade 3 cases (N=107) to determine target depth of necrosis needed to achieve high efficacy; and a pilot study (N=5) investigating depth of necrosis achieved with the adapted device to assess efficacy. Results: Discussion groups revealed 4 priority themes for device development in addition to the need to ensure high efficacy and safety and low cost: improved portability, durability, ease of use, and potential for cure. Adaptions to the original CryoPen system included a single-core, single-tip model; rugged carrying case; custom circuit to allow car battery charging; and sterilization by high-level disinfection. In bench testing, there were no significant differences in tip temperature or heat extraction capability between the adapted CryoPen and the standard cryotherapy device. In 80% of the cases in the pilot study, the adapted CryoPen achieved the target depth of necrosis 3.5 mm established in the pathology review. Conclusion: The LMIC-adapted CryoPen overcomes barriers to standard gas-based cryotherapy by eliminating dependency on gas, increasing portability, and ensuring consistent freeze temperatures. Further testing and evaluation of the adapted CryoPen will be pursued to assess scalability and potential impact of this device in decreasing the cervical cancer burden in LMICs.
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44

Erith, Samuel. "Fitness assessment and recovery strategies for soccer." Thesis, Loughborough University, 2007. https://dspace.lboro.ac.uk/2134/12653.

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In recent years our understanding of the physical demands of soccer has improved. We know that the intensity at which the game is played has increased and that the fixture schedules for professional teams can often be very congested. These factors are likely to have increased the importance placed on the physical condition of players. Therefore, the process of monitoring the fitness levels of players is likely to be an important task within clubs. Any fitness assessments that are employed need to be sensitive enough to detect changes that may result from different training stimuli. A further critical consideration for clubs is what are the best practices to implement in order to maximise recover between matches? The two areas that are central to successful recovery of performance are the restoration of muscle and liver glycogen stores and the rapid reduction of muscle soreness. We have a good understanding of the importance of carbohydrate feeding in the immediate hours following the completion of exercise, furthermore that high levels of carbohydrate consumed during short recovery periods can improve subsequent endurance running capacity in both continuous and intermittent exercise. However, there is dearth of literature investigating the effects that different types (glycemic index) of carbohydrates have on subsequent performance of high intensity intermittent exercise. Furthermore, we know that the movement patterns experienced in soccer commonly induce symptoms of muscle damage. Despite this there is little research based information on modalities that reduce these potentially detrimental side-effects (Bamett, 2006). For these reasons the series of investigations that have been conducted in this thesis were designed with the intent to examine areas that are critical to the preparation and recovery of soccer players. The first of five experimental chapters collated information on the use of fitness testing within English professional football. It was concluded that the practise of fitness testing players is extremely commonplace and that field-based testing protocols were far more popular an assessment method. The second experimental chapter went on to demonstrate that the most commonly used fitness test within professional football (MSFT) was sensitive enough to detect performance changes that occur as a result of training. A further finding within the context of the question was that it is possible for female players to significantly improve aerobic capabilities with additional high intensity aerobic training. The third experimental chapter investigated the effect different glycemic index high CHO diets could have on recovery of performance following 90 min of intermittent soccer type exercise. This study concluded that consuming either predominately high or low GI CHO mixed meals in the 24h recovery period between bouts of high intensity prolonged intermittent exercise had no difference on measures of performance. The final two experimental chapters went on to investigate the effects of cold water immersion on indices of muscle damage following intermittent exercise. Results from these investigations suggest that submerging individuals in 10°C water immediately following high intensity intermittent exercise reduces some but not all indices of muscle damage. In summary, fitness assessments of players are commonly made within professional football clubs. The most common test used was the MSFT and this appears to be sensitive to changes that result as a consequence of training. During recovery from high intensity intermittent exercise the importance of carbohydrates is apparent although the type of carbohydrate appears to be less important, furthermore, cold-water immersion may be effective in reducing some but not all indices of muscle damage.
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45

AraÃjo, NÃvea Braga de. "AvaliaÃÃo dos efeitos inflamatÃrios produzidos pelo nitrogÃnio lÃquido em lÃngua de rato." Universidade Federal do CearÃ, 2007. http://www.teses.ufc.br/tde_busca/arquivo.php?codArquivo=595.

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CoordenaÃÃo de AperfeiÃoamento de Pessoal de NÃvel Superior
A crioterapia à a destruiÃÃo intencional de um tecido por meio da aplicaÃÃo de temperaturas extremamente baixas. à um mÃtodo versÃtil empregado no tratamento de inÃmeras lesÃes benignas e malignas, provenientes de tecidos moles ou duros. A pesquisa teve como objetivo avaliar os efeitos inflamatÃrios produzidos pela criocirurgia quando aplicada em lÃngua de rato. O nitrogÃnio lÃquido foi aplicado a 1 cm da ponta da lÃngua por meio de sonda fechada de 1mm de diÃmetro. Setenta e cinco ratos machos da linhagem Wistar (300-400 g) foram divididos em trÃs grupos de vinte e cinco animais. O grupo A recebeu uma aplicaÃÃo de um minuto, o grupo B duas aplicaÃÃes de um minuto com intervalo de cinco minutos entre as aplicaÃÃes, e o grupo C, trÃs aplicaÃÃes com intervalo de cinco minutos. Os grupos foram subdivididos em cinco subgrupos de cinco animais, cada um. Cada subgrupo foi sacrificado em dias preestabelecidos, a contar do dia da aplicaÃÃo: seis horas, 24 horas, 72 horas, sete dias e 14 dias. Dois animais serviram de grupo-controle, e nenhuma terapia foi instituÃda. ApÃs os perÃodos mencionados, os ratos foram sacrificados, as lÃnguas foram removidas, processadas e coradas pela hematoxilina e eosina (HE). Os parÃmetros histolÃgicos considerados foram: infiltrado inflamatÃrio, hemorragia, vasodilataÃÃo, edema, ulceraÃÃo, reepitelizaÃÃo, caracterÃsticas do tecido muscular e necrose. Foram utilizados escores (0, 1, 2 e 3), de forma que cada amostra recebeu um valor. O estudo demonstrou uma maior intensidade de reaÃÃo inflamatÃria com a repetiÃÃo dos ciclos. A crioterapia à capaz de produzir um grau de inflamaÃÃo capaz de causar destruiÃÃo tecidual
Cryotherapy is the intentional destruction of a tissue by means of applying extremely low temperatures. It is a versatile method that has been used in the treatment of innumerable benign and malignant lesions, either in the soft or hard tissues. The aim of this research was to assess the inflammatory effects produced by cryosurgery when applied to rat tongues. Liquid nitrogen was applied at 1 cm from the tip of the tongue by means of a closed probe 1mm in diameter. Seventy-five male Wistar rats (300-400 g) were divided into three groups of twenty-five animals. Group A received 1 application lasting 1 minute; group B two applications of 1 minute with a 5-minute interval between the applications, and group C, three applications with a 5-minute interval. The groups were subdivided into five subgroups of five animals each. Each subgroup was sacrificed on pre-established times, counted as from the day of the application: 6 hours, 24 hours, 72 hours, 7 days and 14 days. Two animals served as control group, in which no therapy was instituted. After the above-mentioned periods, the rats were sacrificed; the tongues were removed, processed and stained with hematoxylin and eosin (HE). The histological parameters considered were: inflammatory infiltrate, hemorrhage, vasodilatation, edema, ulceration, reepithelization, muscle tissue features and necrosis. Scores were established (0, 1, 2 and 3) so that each sample received a value. The study demonstrated greater inflammatory effects with repetition of the cycles. The cryotherapy may to produce a inflammation degree able to cause tissue destruction
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46

Lucas, Ronaldo. "Monitorização e mensuração tomográfica de diferentes técnicas de crioterapia em pele de cães da raça Beagle, e sua relação com as medidas da necrose estimadas pela histopatologia." Universidade de São Paulo, 2004. http://www.teses.usp.br/teses/disponiveis/10/10136/tde-19102006-144342/.

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O uso do frio pela medicina é muito antigo, utilizado inicialmente de forma empírica, teve grandes avanços nos séculos XIV e XX, evoluindo juntamente com a Física. O surgimento de novas técnicas e equipamentos, possibilitou à crioterapia tornar-se uma importante opção no tratamento de neoplasias, benignas e malignas, de diferentes órgãos (tais como fígado, próstata, pâncreas e mamas) e sistemas (ósseo, neurológico e tegumentar). O grande desenvolvimento tecnológico permitiu além do maior número de indicações, melhores resultados, mormente com o uso de técnicas de imagem para o acompanhamento do procedimento. Porém, poucos são os trabalhos que enfocam a monitorização e mensuração do congelamento, pela tomografia computadorizada, bem como avaliação da necrose obtida. No presente trabalho propôs-se avaliar as relações entre as medidas obtidas pela tomografia computadorizada, em 20 cães da raça Beagle, durante o congelamento por aplicação do nitrogênio pela sonda fechada (75 segundos), spray (75 e 135 segundos) e derramamento (75 segundos), comparando estas medidas com aquelas mensuradas pela histopatologia da necrose provocada, para posteriormente avaliar a efetividade dos métodos e criar protocolos de tratamento. Os valores de diâmetro, raio, profundidade e volume do congelamento foram comparados entre si e, com os respectivos valores da necrose após 96 horas do procedimento. Os valores foram submetidos a análise de variância de medidas repetidas e teste de Bonferroni (p<0,05). Constatou-se que: a técnica de sonda fechada oferece congelamento e subseqüente necrose mais superficial que os outros métodos, sendo a técnica menos efetiva; em todas as técnicas o volume, diâmetro e profundidade são inferiores no tecido necrosado quando comparados aos seus similares naquele congelado; em nenhuma das quatro técnicas a profundidade de congelamento foi equivalente ao seu raio. Finalmente, houve a possibilidade de desenvolvimento de protocolos alternativos de congelamento a partir da profundidade de necrose pretendida (hf), obtendo-se como resultado (sonda - Di = hf / 0,29; spray I; Di = hf / 0,31; spray II - Di = hf / 0,35; derramamento -Di = hf / 0,38) o diâmetro do congelamento (Di) necessário para o êxito do tratamento
The use of cold by Medicine is a very old practice, initially used empirically, which had significant advances in the XIV and XX centuries, developing along with Physics. The appearance of new techniques and equipment turned cryotherapy into an important option in the treatment of benign and malignant neoplasms in different organs (such as the liver, the prostate, the pancreas and breasts) and systems (bone, neurological and tegumentary). The large technological development resulted in a higher number of indications as well as better results, especially with the concomitant use of imaging techniques to follow the procedure. However, few studies focus on the monitoring and mensuration of freezing through computed tomography, as well as the assessment of the resulting necrosis. Our study aims at evaluating the association between the measurements obtained through computed tomography in 20 Beagle dogs during freezing by liquid nitrogen use through a probe (75 sec), spray (75 and 135 sec) and overflow (75 sec), comparing these measurements to those obtained through histopathological analysis of the resulting necrosis, for later evaluation of the effectiveness of the methods and design of better treatment protocols. The values of diameter, radius, depth and volume of freezing were compared among them and also with the respective necrosis values 96 hours after the procedure. The values were submitted to analysis of variance of repeated measurements and Bonferroni test (p<0.05). We observed that the closed probe technique causes a more superficial freezing and resulting necrosis when compared to the other methods, being the less effective technique. In all techniques, the volume, diameter and depth are lower in the necrotic tissue when compared to those in the frozen tissue; none of the four techniques showed that freezing depth was equivalent to its radius. Finally, alternative freezing protocols could be developed from the depth of the intended necrosis (hf), resulting in the freezing diameter (Di) (probe - Di = hf/0.29; spray I; Di = hf/0.31; spray II Di = hf/0.35; overflow Di = hf/0.38), which is necessary for therapy success
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47

Pereira, Luís Filipe Mendes. "As diferentes modalidades da crioterapia e os seus efeitos na resistência passiva muscular." Bachelor's thesis, [s.n.], 2011. http://hdl.handle.net/10284/2869.

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Trabalho apresentado à Universidade Fernando Pessoa como parte dos requisitos para obtenção do grau de Licenciado em Fisioterapia
Objectivo: A aplicação de crioterapia no tratamento de lesões faz parte do quotidiano dos fisioterapeutas e desportistas. Apesar do seu efeito analgésico e anti-inflamatório ser consensual, existe actualmente pouca informação relativamente ao seu efeito ao nível das propriedades visco-elásticas do tecido muscular. Deste modo, este estudo pretende analisar as diferentes modalidades da crioterapia e os seus efeitos, bem como o efeito da crioterapia na resistência passiva muscular. Método: Foi realizada uma revisão da literatura na B-On através da Medline, Pubmed, Scielo e EBSCO e no Google Scholar. Resultados: Após a análise dos estudos seleccionados verificou-se os métodos de crioterapia mais utilizados, nomeadamente o gelo picado, compressas de gelo, pacotes de gel congelado e imersão em água fria. Contudo nem todos os estudos apresentaram efeitos significativos na resistência passiva muscular após a crioterapia. Conclusão: O presente estudo, sugere que os efeitos agudos após a aplicação de crioterapia não produz alteração na resistência passiva muscular, devido à rigidez, embora os seus efeitos analgésicos e a rápida recuperação da função neuromuscular sejam comprovados. Objective: The application of cryotherapy in the treatment of injuries is part of everyday physical therapists and sports. Despite its analgesic and anti-inflammatory to be consensual, there is currently little information on the effect in terms of visco-elastic properties of muscle tissue. Therefore, this study aims to analyze the different forms of cryotherapy and its effects, as well as the effect of cryotherapy on muscle passive resistance. Method: We performed a literature review on the B-On through the Medline, Pubmed, Scielo and EBSCO and Google Scholar. Results: After analysis of selected studies it was found the most commonly used methods of cryotherapy, including the crushed ice, ice packs, frozen gel packs and immersion in cold water. However not all studies showed a significant effect on passive muscle strength after cryotherapy. Conclusions: This study suggests that the acute effects after application of cryotherapy produces no change in muscle passive resistance due to stiffness, although their analgesic effects and rapid recovery of neuromuscular function are proven.
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48

Kucherenko, M. Y. "Cryomedicine." Thesis, Sumy State University, 2014. http://essuir.sumdu.edu.ua/handle/123456789/45337.

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Cryotherapy is a relatively new form of treatment in which the body is briefly exposed to very cold temperatures in order to promote healing and other therapeutic results. Cryotherapy has been shown to decrease inflammation of the body’s tissues, muscles and joints. It can also help improve the body’s circulation and healing, and also slow down cellular metabolism and reproduction. Cryotherapy can help to reduce pain and muscle spasms in the body as well as reduce the swelling of injuries. Cryotherapy has also been shown to promote faster healing in joint, muscle and tendon injuries.
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Dern, Kathryn V. "Evaluation of the Effects of Therapeutic Digital Hypothermia on Lamellar Signaling in Sepsis Related Laminitis." The Ohio State University, 2017. http://rave.ohiolink.edu/etdc/view?acc_num=osu1492639420006617.

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50

Rosada, Emanuele. "La crioterapia come tecnica di recupero da intenso esercizio fisico negli atleti: analisi della recente letteratura." Bachelor's thesis, Alma Mater Studiorum - Università di Bologna, 2020. http://amslaurea.unibo.it/21975/.

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BACKGROUND: diverse modalità di recupero sono attualmente utilizzate dagli atleti nel tentativo di compensare gli effetti negativi di un intenso esercizio fisico. Ad oggi, ci sono molteplici approcci terapeutici volti al ridurre i tempi di recupero, superando sia l’indolenzimento muscolare a insorgenza ritardata (DOMS dall'inglese Delayed Onset Muscle Soreness) che il dolore indotto dall’esercizio, per migliorare le prestazioni. OBIETTIVO: questa Revisione si è limitata ai soli articoli riguardanti studi clinici randomizzati e controllati RCT (dall’ inglese Randomized Controlled Trial) e ha lo scopo di verificare l’efficacia dei trattamenti crioterapici come la crioterapia su tutto il corpo (WBC, dall’inglese Whole Body Criotherapy), e la crioterapia come immersione in acqua fredda (CWI, dall’inglese Cold Water Immersion) come modalità di recupero dopo un intenso esercizio fisico. METODI DI RICERCA: sono state consultate le banche dati elettroniche COCHRANE, PEDro e PubMed. Sono stati inclusi solo RCT che prendessero in esame il trattamento con WBC o con CWI nel recupero da esercizio fisico intenso negli atleti. RISULTATI:sono stati individuati 5 RCT che analizzano gli effetti della crioterapia sui seguenti parametri: danni all'apparato muscolo-scheletrico, riduzione dei tempi di recupero e miglioramento delle prestazioni funzionali. CONCLUSIONI: L’analisi dei risultati degli RCT inclusi, mostra che il solo trattamento con crioterapia, non sembrerebbe essere sufficente per il recupero da DOMS in quanto promuoverebbe modesti miglioramenti su eventuali danni all’apparato muscolo-scheletrico, riduzione dei tempi di recupero e performance, i miglioramenti potrebbero essere indotti da una maggiore ossigenazione dei muscoli e da una riduzione dello sforzo cardiovascolare. L'analisi mosta anche che la crioterapia può provocare un effetto benefico dal punto di vista psicologico che si traduce in una diminuzione della percezione soggettiva del dolore.
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