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Journal articles on the topic 'CSV 5' 3''

Author: Grafiati

Published: 4 June 2021

Last updated: 15 February 2022

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1

Cromeans, Theresa, Geun Woo Park, Veronica Costantini, et al. "Comprehensive Comparison of Cultivable Norovirus Surrogates in Response to Different Inactivation and Disinfection Treatments." Applied and Environmental Microbiology 80, no. 18 (2014): 5743–51. http://dx.doi.org/10.1128/aem.01532-14.

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ABSTRACTHuman norovirus is the leading cause of epidemic and sporadic acute gastroenteritis. Since no cell culture method for human norovirus exists, cultivable surrogate viruses (CSV), including feline calicivirus (FCV), murine norovirus (MNV), porcine enteric calicivirus (PEC), and Tulane virus (TuV), have been used to study responses to inactivation and disinfection methods. We compared the levels of reduction in infectivities of CSV and Aichi virus (AiV) after exposure to extreme pHs, 56°C heating, alcohols, chlorine on surfaces, and high hydrostatic pressure (HHP), using the same matrix a

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Chen, Tsing-Chang, Jenq-Dar Tsay, Jun Matsumoto, and Jordan Alpert. "Forecast Advisory for a Cold-Season Heavy Rainfall/Flood Event That Developed from Multiple Interactions of the Cold-Surge Vortex with Cold-Surge Flows in the South China Sea." Weather and Forecasting 32, no. 3 (2017): 797–819. http://dx.doi.org/10.1175/waf-d-16-0148.1.

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Abstract The peak intensity occurrence frequency over the life cycles of parent cold-surge vortices (CSVs) for heavy rainfall/flood (HRF) events is classified into two types depending on their life cycles having two or three peak intensities, denoted as HRF2 or HRF3, respectively. The formation of an HRF2 event from its parent CSV(HRF2) formation is ≤5 days, while the formation of an HRF3 event is ≥6 days. The latter group contributes ~57% of the total number of HRF events. As a result of some model constraints, the formation and development of HRF3 events are not well forecasted by the Global

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Dey, Avijit, Shyam S. Paul, Akula V. Umakanth, Basrur V. Bhat, Puran C. Lailer, and Satbir S. Dahiya. "Nutritional potential, in vitro ruminal fermentation kinetics and methanogenesis of stover from newer cultivars of sorghum (Sorghum bicolor) in buffalo." Animal Production Science 60, no. 17 (2020): 1969. http://dx.doi.org/10.1071/an19150.

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Context In developing countries of south Asia and Africa, cereal crop residues provide important fodder resources for ruminants. Genetic improvement through plant breeding for high-quality crop residues as well as for grain yield is gaining in demand among mixed crop–livestock farmers. Aims The present study investigated the potential nutritional quality, in vitro ruminal fermentation kinetics, gas production, enzyme activities and methane production of stover of newly developed brown midrib cultivars of sorghum (Sorghum bicolor (L.) Moench) compared with other cultivars in buffalo (Bubalus bu

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Ulrich, Kerstin, and Anja Palmowski-Wolfe. "Comparing Three Different Contrast Sensitivity Tests in Adults and in Children with and without Amblyopia." Klinische Monatsblätter für Augenheilkunde 236, no. 04 (2019): 434–37. http://dx.doi.org/10.1055/a-0853-1683.

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Abstract Background Tests of contrast sensitivity (CS) are not routinely performed in the clinic, although CS is reduced in many conditions, such as amblyopia or glaucoma. This may be due to perceived time constraints or unaffordability of equipment. Patients and Methods Monocular CS functions obtained with the FACT, CSV 1000E, and Lea Symbols were compared in 19 healthy subjects aged 24 – 78 years and 24 subjects aged 5 – 16 years, 9 of whom had amblyopia. Results CS functions could be obtained with all three tests. The tests were equally comfortable for young and adult patients, and took les

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Agudelo Guevara, Ana María, Alejandro León Álvarez, and Jorge Mario Estrada Álvarez. "Intervalos de referencia de agudeza visual y sensibilidad al contraste en una población escolar de Pereira, Colombia." Ciencia & Tecnología para la Salud Visual y Ocular 15, no. 2 (2017): 39. http://dx.doi.org/10.19052/sv.4039.

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Introducción: las pruebas que evalúan la agudeza visual (AV) y la función de sensibilidad al contraste (FSC) permiten cuantificar e identificar la calidad de la visión. En Colombia, los intervalos de referencia para estas dos pruebas visuales se han establecido a partir de parámetros hallados principalmente en poblaciones foráneas. Objetivos: determinar los intervalos de referencia de la AV y la FSC en una población escolar sana de 5 a 19 años de Pereira, Colombia. Materiales y métodos: estudio descriptivo-transversal en el que se evaluaron 626 sujetos entre los 5 y los 19 años de edad, identi

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Huang, Ting-Lin, Yu-Xian Li, and Hui Zhang. "Theoretical analysis on non-uniformity of water distribution and influence of construction parameters on settling efficiency." Water Science and Technology 58, no. 5 (2008): 1007–14. http://dx.doi.org/10.2166/wst.2008.458.

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During the reconstruction of horizontal flow tanks into inclined settling tanks in Chinese water plants, uniformity of water distribution has not been solved theoretically. Based on the concepts of hydraulics, a model of inclined tanks, including the ratio (L/B) of tank length (L) to width (B), diameter of inclined tubes (d) and height of the water distribution area (h1) and so on, was established to simulate and analyze the effects of these parameters on Non-Uniformity of Water Distribution (NUWD). The influences of NUWD on settling efficiency were also analyzed based on Yao's formula. Simula

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Kalabikhina, Irina E., and Evgeny P. Banin. "Database “Childfree (antinatalist) communities in the social network VKontakte”." Population and Economics 5, no. 2 (2021): 92–96. http://dx.doi.org/10.3897/popecon.5.e70786.

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The database contains an upload of text comments in Russian from the social network VKontakte in .csv format (UTF-8 encoding). The comments are collected from communities, which discuss pregnancy, childhood, motherhood, paternity, etc. The upload contains comments under the posts with which the interaction took place. The absolute amount of likes is used as a criterion (comments are collected where the number of likes is greater than or equal to 5). The text data is processed (stemmization and lemmatization). The data are suitable for thematic analysis (e.g. LDA — Latent Dirichlet Allocation),

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8

TRUYEN, U., T. MÜLLER, R. HEIDRICH, K. TACKMANN, and L. E. CARMICHAEL. "Survey on viral pathogens in wild red foxes (Vulpes vulpes) in Germany with emphasis on parvoviruses and analysis of a DNA sequence from a red fox parvovirus." Epidemiology and Infection 121, no. 2 (1998): 433–40. http://dx.doi.org/10.1017/s0950268898001319.

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The seroprevalence of canine parvovirus (CPV), canine distemper virus (CDV), canine adenovirus (CAV) and canine herpesvirus (CHV) infections in red foxes (Vulpes vulpes) was determined in fox sera collected between 1991 and 1995. A total of 500 sera were selected and the seroprevalences were estimated to be 13% (65 of 500 sera) for CPV, 4·4% (17 of 383 sera) for CDV, 3·5% (17 of 485 sera) for CAV, and 0·4% (2 of 485 sera) for CHV, respectively. No statistically significant differences were observed between the two (rural and suburban) areas under study.Parvovirus DNA sequences were amplified f

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Purwayadi, Teguh. "SYSTEMATIC MAPPING OF PERFORMANCE ASSESSMENT RESEARCH: BIBLIOMETRIC STUDY WITH VOSVIEWER." Advances in Social Sciences Research Journal 7, no. 9 (2020): 151–61. http://dx.doi.org/10.14738/assrj.79.8984.

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This article aims to find a map of the development of research on performance assessment. The study was conducted by searching through the Scopus database with the keyword performance assessment. The data from the search results are then analyzed descriptively based on the year of publication, the country that published the performance assessment research, and the focus of the research. To obtain a map of research development, the data from the Scopus database is exported into a Comma Separated Values (CSV) file format, then processed and analyzed using the VOSViewer application program to f

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Schwarze, Julia Katharina, Johnny Duerinck, Ines Dufait, et al. "A phase I clinical trial on intratumoral and intracavitary administration of ipilimumab and nivolumab in patients with recurrent glioblastoma." Journal of Clinical Oncology 38, no. 15_suppl (2020): 2534. http://dx.doi.org/10.1200/jco.2020.38.15_suppl.2534.

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2534 Background: Intravenous (IV) administration of ipilimumab (IPI) and nivolumab (NIVO) has low activity in recurrent glioblastoma (rGB). Intratumoral (IT) and intracavitary (IC) administration of IPI and NIVO is under evaluation in the GlITIpNi phase I clinical trial. Methods: Patients (pts) with resectable rGB were recruited to cohorts C1, C2 and C4; pts with non-resectable rGB were recruited in C3 (biopsy only). IT administration (brain tissue lining the resection cavity during surgery) of IPI (10 mg)(C1), or IPI (5 mg) plus NIVO (10 mg)(C2, C3 and C4), was followed by IC administration o

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11

Qadri, Firdausi, Swadesh Kumar Das, A. S. G. Faruque, et al. "Prevalence of Toxin Types and Colonization Factors in Enterotoxigenic Escherichia coli Isolated during a 2-Year Period from Diarrheal Patients in Bangladesh." Journal of Clinical Microbiology 38, no. 1 (2000): 27–31. http://dx.doi.org/10.1128/jcm.38.1.27-31.2000.

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ABSTRACT The prevalence of toxin types and colonization factors (CFs) of enterotoxigenic Escherichia coli (ETEC) was prospectively studied with fresh samples ( n = 4,662) obtained from a 2% routine surveillance of diarrheal stool samples over 2 years, from September 1996 to August 1998. Stool samples were tested by enzyme-linked immunoassay techniques and with specific monoclonal antibodies for the toxins and CFs. The prevalence of ETEC was 14% ( n = 662), with over 70% of the strains isolated from children 0 to 5 years of age, of whom 93% were in the 0- to 3-year-old age range. Of the total E

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Vilchez, Samuel, Sylvia Becker-Dreps, Erick Amaya, et al. "Characterization of enterotoxigenic Escherichia coli strains isolated from Nicaraguan children in hospital, primary care and community settings." Journal of Medical Microbiology 63, no. 5 (2014): 729–34. http://dx.doi.org/10.1099/jmm.0.066779-0.

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Enterotoxigenic Escherichia coli (ETEC) is one of the most common causes of diarrhoea among young children in developing countries. ETEC vaccines offer promise in reducing the burden of ETEC disease, but the development of these vaccines relies on the characterization of ETEC isolates from a variety of settings. To best reflect the full spectrum of ETEC disease in León, Nicaragua, the aim of this study was to characterize ETEC strains isolated from children with diarrhoea attending different settings (hospital, primary care clinics and in the community) and children from different age groups.

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13

Lo, Michael K., Mark Tilgner, Kristen A. Bernard, and Pei-Yong Shi. "Functional Analysis of Mosquito-Borne Flavivirus Conserved Sequence Elements within 3′ Untranslated Region of West Nile Virus by Use of a Reporting Replicon That Differentiates between Viral Translation and RNA Replication." Journal of Virology 77, no. 18 (2003): 10004–14. http://dx.doi.org/10.1128/jvi.77.18.10004-10014.2003.

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ABSTRACT We have developed a reporting replicon of West Nile virus (WNV) that could be used to quantitatively distinguish viral translation and RNA replication. A Renilla luciferase (Rluc) gene was fused in-frame with the open reading frame of a subgenomic replicon in the position where the viral structural region was deleted, resulting in RlucRep. Transfection of BHK cells with RlucRep RNA yielded two distinctive Rluc signal peaks, one between 2 and 10 h and the other after 26 h posttransfection. By contrast, only the 2- to 10-h Rluc signal peak was observed in cells transfected with a mutant

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14

Hübner, Silvia de Oliveira, Felipe Geraldes Pappen, Jerônimo Lopes Ruas, Gilberto D'Ávila Vargas, Geferson Fischer, and Telmo Vidor. "Exposure of pampas fox (Pseudalopex gymnocercus) and crab-eating fox (Cerdocyon thous) from the Southern region of Brazil to Canine distemper virus (CDV), Canine parvovirus (CPV) and Canine coronavirus (CCoV)." Brazilian Archives of Biology and Technology 53, no. 3 (2010): 593–97. http://dx.doi.org/10.1590/s1516-89132010000300012.

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The exposure of 13 Brazilian free-ranging nondomestic canids (five pampas fox - Pseudalopex gymnocercus and eight crab-eating fox -Cerdocyon thous) from Southern region of Brazil, to Canine distemper virus (CDV), canine parvovirus (CPV) and Canine coronavirus (CCoV) was investigated. Antibodies against CDV were detected in 38.5% (5/13) of the samples. There were anti-CDV antibodies in 60% (3/5) of P. gymnocercus and in 25% (2/8) of C. thous. The frequency was higher among the adults and males. Eleven canids (84.6%) presented antibodies against CPV, 80% (4/5) were from P. gymnocercus and 87.5%

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15

Gusta, Immanuel Luigi Da, and Johan Setiawan. "Data Visualization Indicator Disease (Malaria, Dengue Fever, and Measles) in The Year 2012-2015." International Journal of New Media Technology 4, no. 2 (2017): 87–93. http://dx.doi.org/10.31937/ijnmt.v4i2.785.

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The aim of this paper are: to create a data visualization that can assist the Government in evaluating the return on the development of health facilities in the region and province area in term of human resources for medical personnel, to help community knowing the amount of distribution of hospitals with medical personnel in the regional area and to map disease indicator in Indonesia. The issue of tackling health is still a major problem that is not resolved by the Government of Indonesia. There are three big things that become problems in the health sector in Indonesia: infrastructure has no

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Yu, Guo-Pan, Zhao Yin, Zhiping Fan, et al. "The Efficacy and Safety of Cidofovir in Salvage Therapy for CMV Infection in the Patients with Haploid Hematopoietic Stem Cell Transplantation." Blood 134, Supplement_1 (2019): 5659. http://dx.doi.org/10.1182/blood-2019-126705.

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Cidofovir (CDV) is a nucleotide analogue with broad antiviral activity and has been approved for the treatment of cytomegalovirus (CMV) retinitis in patients with acquired immunodeficiency syndrome. Data on the use of CDV for anti-CMV treatment in the patients with allogeneic hematopoietic stem cell transplantation (allo-HSCT) are limited. To evaluate the efficacy and safety of CDV in salvage treatment of CMV infection after allo-HSCT, we prospectively enrolled 18 patients with CMV infection after allo-HSCT in this study, of whom failed or intolerant to preemptive antiviral therapy. Dose of CD

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17

Preetz, W., A. Franken, and M. Rath. "Darstellung, 11B-, 13C-NMR- und Schwingungsspektren der closo-Hexaborate [B6H5(CN)12- und cis-[B6H4(CN)2]2− sowie Kristallstruktur von Cs2[B6H5(CN)] / Preparation, 11B,13C NMR and Vibrational Spectra of the closo-Hexaborates [B6H5(CN)]2- and cis-[B6H4(CN)2]2-, and the Crystal Structure of Cs2[B6H5(CN)]." Zeitschrift für Naturforschung B 48, no. 5 (1993): 598–602. http://dx.doi.org/10.1515/znb-1993-0509.

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By reaction of Cs2[B6H6] with in situ generated dicyanogen in aqueous alkaline solution the monocyanohydrohexaborate Cs2[B6H5(CN)] and the dicyanohydrohexaborate cis-Cs2[B6H4(CN)2] are formed. The compounds have been separated by ion exchange chromatography on diethylaminoethyl cellulose. The crystal structure of Cs2[B6H5(CN)] was determined from single crystal X-ray diffraction analysis; monoclinic, space group P21/a with a = 9.540(8), b = 9.977(3), c = 10.578(2)Å, β = 105.06(2)°. The B6 octahedron is compressed in the direction of the nearly linear B—CN bond by about 5%, with bond lengths be

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Preetz, W., and P. Erlhöfer. "Darstellung und Schwingungsspektren von Fluoro-Chloro- Platinaten(IV) einschließlich der Stereoisomeren / Preparation and Vibrational Spectra of Fluoro-Chloro-Platinates(IV) Including Stereoisomers." Zeitschrift für Naturforschung B 44, no. 4 (1989): 412–18. http://dx.doi.org/10.1515/znb-1989-0408.

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The reaction of [PtCI6]2- with BrF3 generates the mixed complexes [PtFnC6-n]2- , n = 1- 5, of which the species with n = 2. 3, 4 are cis-configurated. Due to the stronger trans-effect of Cl compared to F, on treatment of [PtF5Cl]2- and cis-[PtF4Cl2]2- with Cl- the trans-isomers are formed stereospecifically. The pure fluoro-chloro-platinates(IV) are separated by ion exchange chromatography on diethylaminoethyl-cellulose. The vibrational spectra o f the mixed ligand complexes are completely assigned according to point groups D4h, C4v, C3v and C2v. The Pt-Cl stretching vibrations of [PtF5Cl]2-,

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Irmer, K., та W. Preetz. "Normalkoordinatenanalyse an Oktaederkomplexen des Typs [MXnY6-n]z-, M = Ru, Rh, Os, Ir, Pt; Χ ≠ Y = F, Cl, Br; n = 0-6; z = 1 -3 / Normal Coordinate Analysis on Octahedral Complexes of the Type [ΜΧnΥ6-n]z-, M = Ru, Rh, Os, Ir, Pt; Χ ≠ Y = F, Cl, Br; n = 0-6; z = 1-3". Zeitschrift für Naturforschung B 46, № 9 (1991): 1200–1206. http://dx.doi.org/10.1515/znb-1991-0911.

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Normal coordinate analyses for all compounds of the series [MXnY6-1]z-, M = Ru, Rh, Os, Ir, Pt; Χ ≠ Y = F, Cl, Br; n = 0-6; z = 1-3, including the geometric isomers for n = 2, 3, 4 have been performed, based on a general valence force field. For the isostructural species of the point symmetries Oh (n = 0, 6), D4h (2,4, trans), C4v (1, 5), C3v (3, fac), C2v (2,4, cis; 3, mer) sequences of decreasing frequencies are established. Due to the different trans influences X &lt; Y (F &lt; Cl &lt; Br) in asymmetric axes X′–M–Y′, the M–Y′ bonds are strengthened and the M – X′ bonds are weake

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20

Goldstein, Walter A. "The effect of farming systems on the relationship of corn root growth to grain yields." American Journal of Alternative Agriculture 15, no. 3 (2000): 101–9. http://dx.doi.org/10.1017/s0889189300008602.

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AbstractThe Wisconsin Integrated Cropping Systems Trial has been comparing different farming systems on two farm sites in southern Wisconsin since 1989. Inexplicable differences in the yields of corn grown in three systems stimulated research on the relationship between yield and the dynamics of root growth. The three systems were continuous corn with mineral fertilizer (CS1), corn—soybean—winter wheat—red clover (CS3), and corn—oat + alfalfa—alfalfa with dairy manure applied (CS5). Four or five sequential root samplings were taken each growing season on two sites for 3 years. Soil monoliths w

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21

Preetz, W., and H. J. Steinebach. "Darstellung und Charakterisierung der Chloro-Bromo-Iridate(III) und -(IV) einschließlich der Stereoisomeren / Preparation and Characterisation of Chloro-Bromo-Iridates(III) and -(IV) Including Stereoisomers." Zeitschrift für Naturforschung B 40, no. 6 (1985): 745–54. http://dx.doi.org/10.1515/znb-1985-0610.

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AbstractThe mixed chloro-bromo complexes [IrClnBr6-n]2- and [IrClnBr6-n]3-, n = 1 - 5. were separated by ion exchange chromatography on diethylaminoethylcellulose. Due to the stronger trans-effect of Br compared with Cl, on treatment of [IrBr6]2- 3- with Cl- nearly pure cis/fac-isomers and by reaction of [IrCl6]2,3- with Br- trans/mer-isomers for n = 2,3,4 were formed. The stereoselectivity of successive ligand exchange reactions is better for the Ir(III) than for the Ir(IV) system. The diamagnetic Ir(III) and the paramagnetic Ir(IV) complexes can be interconverted reversibly by redox reactio

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22

Preetz, W., and W. Kuhr. "Darstellung, Schwingungsspektren und Normalkoordinatenanalyse von Chloro-Bromo-Rhodaten(III) / Preparation, Vibration Spectra and Normal Coordinate Analysis of Chloro-Bromo-Rhodates(III)." Zeitschrift für Naturforschung B 44, no. 10 (1989): 1221–27. http://dx.doi.org/10.1515/znb-1989-1014.

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The mixed chloro-bromo-rhodates(III) [RhClnBr6-n]3-, n = 1-5, have been separated for the first time by ion exchange chromatography on diethylaminoethyl-cellulose. Due to the stronger trans-effect of Br, as compared with Cl, on treatment of [RhBr6]3- with conc. HCl nearly pure cis/fac-isomers for n = 2, 3, 4 are formed. The reaction of [RhCl6]3- with conc. HBr yields mixtures of the cis/trans-isomers for n = 2, 4, which cannot be separated, but mer-[RhCl3Br3]3 is formed stereospecifically. The IR and Raman spectra of all isolated mixed ligand complexes are completely assigned according to poin

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23

Kern, Earl R., Deborah J. Collins, W. Brad Wan, James R. Beadle, Karl Y. Hostetler, and Debra C. Quenelle. "Oral Treatment of Murine Cytomegalovirus Infections with Ether Lipid Esters of Cidofovir." Antimicrobial Agents and Chemotherapy 48, no. 9 (2004): 3516–22. http://dx.doi.org/10.1128/aac.48.9.3516-3522.2004.

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ABSTRACT To improve the oral bioavailability of cidofovir (CDV), a series of ether lipid ester prodrugs were synthesized and evaluated for activity against murine cytomegalovirus (MCMV) infection. Four of these analogs, hexadecyloxypropyl (HDP)-CDV, octadecyloxyethyl (ODE)-CDV, oleyloxyethyl (OLE)-CDV, and oleyloxypropyl (OLP)-CDV, were found to have greater activity than CDV against human CMV and MCMV in vitro. The efficacy of oral treatment with these compounds against MCMV infections in BALB/c mice was then determined. Treatment with HDP-CDV, ODE-CDV, OLE-CDV, or OLP-CDV at 2.0 to 6.7 mg/kg

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Sato, Eimei, Maki Inoue, Yuji Takahashi, and Yutaka Toyoda. "Glycosaminoglycans Prevent Induction of Fragmentation of Porcine Oocytes Stimulated by Dibutyryl Cyclic Adenosine 3 ,5- Monophosphate in Culture." Cell Structure and Function 19, no. 1 (1994): 29–36. http://dx.doi.org/10.1247/csf.19.29.

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25

Hong, W. K., C. Nicaise, R. Lawson, et al. "Etoposide combined with cyclophosphamide plus vincristine compared with doxorubicin plus cyclophosphamide plus vincristine and with high-dose cyclophosphamide plus vincristine in the treatment of small-cell carcinoma of the lung: a randomized trial of the Bristol Lung Cancer Study Group." Journal of Clinical Oncology 7, no. 4 (1989): 450–56. http://dx.doi.org/10.1200/jco.1989.7.4.450.

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A total of 353 patients with previously untreated small-cell lung cancer (SCLC) were accrued in this multicenter trial. Patients were randomly assigned to receive one of the following three regimens: cyclophosphamide 1,000 mg/m2 intravenously (IV) day 1, vincristine 1.4 mg/m2 IV day 1, and etoposide 50 mg/m2 IV day 1, followed by etoposide 100 mg/m2/day orally days 2 through 5 (CEV); cyclophosphamide 1,000 mg/m2 IV day 1, vincristine 1.4 mg/m2 IV day 1, and doxorubicin 50 mg/m2 IV day 1 (CAV); cyclophosphamide 2,000 mg/m2 day 1 and vincristine 1.4 mg/m2 IV day 1 (CV). Cycles were repeated ever

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Haiges, Ralf, Monica Vasiliu, David A. Dixon, and Karl O. Christe. "The niobium oxoazides [NbO(N3)3], [NbO(N3)3·2CH3CN], [(bipy)NbO(N3)3], Cs2[NbO(N3)5] and [PPh4]2[NbO(N3)5]." Dalton Transactions 45, no. 26 (2016): 10523–29. http://dx.doi.org/10.1039/c6dt01479h.

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27

Mori, Shigefumi. "On 3-dimensional terminal singularities." Nagoya Mathematical Journal 98 (June 1985): 43–66. http://dx.doi.org/10.1017/s0027763000021358.

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Preetz, W., and A. Wendt. "Darstellung, Schwingungsspektren und Normalkoordinatenanalyse der Chloro-Bromo-Technetate(IV), [TcCl„Br6_n]2-, n = 0-6 / Preparation, Vibrational Spectra and Normal Coordinate Analysis of Chloro-Bromo-Technetates(IV), [TcCln Br6-n]2-, n = 0-6." Zeitschrift für Naturforschung B 46, no. 11 (1991): 1496–502. http://dx.doi.org/10.1515/znb-1991-1107.

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The mixed chloro-bromo-technetates(IV), [TcClnBr6-n2-, n = 1-5, have been separated for the first time by ion exchange chromatography on diethylaminoethyl-cellulose. Due to the stronger trans-effect of Br as compared to Cl, the ligand exchange reactions of [TcBr62- with HCl and of [TcCl6]2- with HBr proceed stereospecifically, to form either cis/fac- or trans/merspecies for n = 2, 3, 4, respectively. To avoid photoisomerization the compounds have to be handled in the absence of light. The IR and Raman spectra of the ten chloro-bromo-techne-tates(IV), including the pure geometrical isomers, hav

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YANG, JUCAI, XUE BAI, CHUNPING LI, WENGUO XU, and WENSHENG XIAO. "EQUILIBRIUM GEOMETRIES AND ELECTRONIC STRUCTURE OF SMALL SILICON MONOHYDRIDES CLUSTERS." International Journal of Modern Physics B 20, no. 06 (2006): 677–95. http://dx.doi.org/10.1142/s0217979206033450.

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The geometries and energies of small silicon monohydride clusters ( Si 2 H – Si 10 H ) have been systematically investigated by density functional theory (DFT) scheme with DZP++ basis sets. Several possible geometric arrangements and electronic states have been considered for each cluster. The results on Si 2 H – Si 4 H are in good accordance with previous ab initio calculation. The geometry of ground state of Si 2 H is found to be a bridged C2v structure, and Si 3 H to be a bridged C2v, while Si 4 H a non-bridged Cs symmetry with 2A′ state. The non-bridged geometries of ground state of Si 5 H

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Tyumentseva, Olga S., Ilya V. Kornyakov, Sergey N. Britvin, Andrey A. Zolotarev, and Vladislav V. Gurzhiy. "Crystallographic Insights into Uranyl Sulfate Minerals Formation: Synthesis and Crystal Structures of Three Novel Cesium Uranyl Sulfates." Crystals 9, no. 12 (2019): 660. http://dx.doi.org/10.3390/cryst9120660.

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An alteration of the uranyl oxide hydroxy-hydrate mineral schoepite [(UO2)8O2(OH)12](H2O)12 at mild hydrothermal conditions was studied. As the result, four different crystalline phases Cs[(UO2)(SO4)(OH)](H2O)0.25 (1), Cs3[(UO2)4(SO4)2O3(OH)](H2O)3 (2), Cs6[(UO2)2(SO4)5](H2O)3 (3), and Cs2[(UO2)(SO4)2] (4) were obtained, including three novel compounds. The obtained Cs uranyl sulfate compounds 1, 3, and 4 were analyzed using single-crystal XRD, EDX, as well as topological analysis and information-based structural complexity measures. The crystal structure of 3 was based on the 1D complex, the

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Stern, Anat, Yiqi Su, Dionysis Neofytos, and Genovefa Papanicolaou. "1761. A Single-Center Experience with Cidofovir for the Treatment of Double-Stranded (ds) DNA Viruses in Hematopoietic Cell Transplant (HCT) Recipients." Open Forum Infectious Diseases 6, Supplement_2 (2019): S647—S648. http://dx.doi.org/10.1093/ofid/ofz360.1624.

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Abstract Background Cidofovir (CDV), a nucleotide analog antiviral, is active against multiple dsDNA viruses relevant in HCT recipients. Despite a broad spectrum of activity, CDV utility is limited due to nephrotoxicity. We describe our experience with CDV in a large contemporary cohort from a single Institution. Methods Retrospective review of adult HCT recipients who received CDV for any indication from 2011 to 2017. Initiation and duration of CDV treatment were at physicians’ discretion. CDV exposure and indications, Serum Creatinine (SCr) and outcomes were extracted from medical records an

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Kagebayashi, Yoshio, Yusuke Mori, and Takatomo Sasaki. "Crystal Growth and Characterization of Nonilinear Optical Crystal CsB₃O₅." IEEJ Transactions on Electronics, Information and Systems 120, no. 7 (2000): 906–9. http://dx.doi.org/10.1541/ieejeiss1987.120.7_906.

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Xiong, X., J. L. Smith, and M. S. Chen. "Effect of incorporation of cidofovir into DNA by human cytomegalovirus DNA polymerase on DNA elongation." Antimicrobial Agents and Chemotherapy 41, no. 3 (1997): 594–99. http://dx.doi.org/10.1128/aac.41.3.594.

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Cidofovir (CDV) (HPMPC) has potent in vitro and in vivo activity against human cytomegalovirus (HCMV), CDV diphosphate (CDVpp), the putative antiviral metabolite of CDV, is an inhibitor and an alternate substrate of HCMV DNA polymerase. CDV is incorporated with the correct complementation to dGMP in the template, and the incorporated CDV at the primer end is not excised by the 3'-to-5' exonuclease activity of HCMV DNA polymerase. The incorporation of a CDV molecule causes a decrease in the rate of DNA elongation for the addition of the second natural nucleotide from the singly incorporated CDV

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Roossinck, Marilyn J., Lee Zhang, and Karl-Heinz Hellwald. "Rearrangements in the 5′ Nontranslated Region and Phylogenetic Analyses of Cucumber Mosaic Virus RNA 3 Indicate Radial Evolution of Three Subgroups." Journal of Virology 73, no. 8 (1999): 6752–58. http://dx.doi.org/10.1128/jvi.73.8.6752-6758.1999.

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ABSTRACT Cucumber mosaic virus (CMV) has been divided into two subgroups based on serological data, peptide mapping of the coat protein, nucleic acid hybridization, and nucleotide sequence similarity. Analyses of a number of recently isolated strains suggest a further division of the subgroup I strains. Alignment of the 5′ nontranslated regions of RNA 3 for 26 strains of CMV suggests the division of CMV into subgroups IA, IB, and II and suggests that rearrangements, deletions, and insertions in this region may have been the precursors of the subsequent radiation of each subgroup. Phylogeny ana

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Lo, Yung-Tsun, Peter E. Nadeau, Shanshan Lin, and Ayalew Mergia. "Establishing Restricted Expression of Caveolin-1 in HIV Infected Cells and Inhibition of Virus Replication." Open Microbiology Journal 8, no. 1 (2014): 114–21. http://dx.doi.org/10.2174/1874285801408010114.

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Background: Caveolin-1 (Cav-1) is the major protein of the caveolae and plays a role in multiple cellular functions and implicated to have anti-HIV activity. Regulated expression of Cav-1 is important for safe and effective use in order to exploit Cav-1 for HIV therapeutic applications. Methods: A series of Cav-1 and GFP expression vectors were constructed under the control of the HIV LTR for conditional expression or CMV promoter and the expression of Cav-1 was monitored in the presence or absence of Tat or HIV infection in order to establish the restricted expression of Cav-1 to HIV infected

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Gammon, Don B., and David H. Evans. "The 3′-to-5′ Exonuclease Activity of Vaccinia Virus DNA Polymerase Is Essential and Plays a Role in Promoting Virus Genetic Recombination." Journal of Virology 83, no. 9 (2009): 4236–50. http://dx.doi.org/10.1128/jvi.02255-08.

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ABSTRACT Poxviruses are subjected to extraordinarily high levels of genetic recombination during infection, although the enzymes catalyzing these reactions have never been identified. However, it is clear that virus-encoded DNA polymerases play some unknown yet critical role in virus recombination. Using a novel, antiviral-drug-based strategy to dissect recombination and replication reactions, we now show that the 3′-to-5′ proofreading exonuclease activity of the viral DNA polymerase plays a key role in promoting recombination reactions. Linear DNA substrates were prepared containing the dCMP

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Faderl, Stefan, Alessandra Ferrajoli, William G. Wierda, et al. "The Combination of Alemtuzumab [Continuous Intravenous Infusion (civ) Followed by Subcutaneous Injection (sc)] Plus Rituximab Has Activity in Patients (pts) with Relapsed Chronic Lymphocytic Leukemia (CLL)." Blood 108, no. 11 (2006): 2827. http://dx.doi.org/10.1182/blood.v108.11.2827.2827.

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Abstract Available data suggest enhanced activity of monoclonal antibodies in combinations. In a previous study of iv bolus alemtuzumab plus rituximab in relapsed CLL, we have shown that the combination is safe and produces a response rate of 54% following a 4-week treatment period (Blood101: 3413, 2003). As questions remain about the optimal dose, schedule and route of administration of alemtuzumab, we have been exploring alemtuzumab by civ followed by sc injections in combination with rituximab in pts with relapsed/refractory CLL who express both CD20 and CD52. Forty-five pts have been enrol

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Thompson, Jeremy R., Emanuele Buratti, Mélissanne de Wispelaere, and Mark Tepfer. "Structural and functional characterization of the 5′ region of subgenomic RNA5 of cucumber mosaic virus." Journal of General Virology 89, no. 7 (2008): 1729–38. http://dx.doi.org/10.1099/vir.0.2008/001057-0.

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The uncapped and ORF-less subgenomic RNA5 is produced in subgroup II strains of cucumber mosaic virus (CMV), but not in subgroup I strains. Its initiation nucleotide (nt 1903) is in a 21 nt conserved sequence (Box1) that is absent in CMV subgroup I. Putative non-coding RNA structural elements surrounding Box1 in the plus and minus strand were identified in silico and by in vitro RNase probing. Four main stem–loop structures (SLM, SLL, SLK and SLJ) were identified between nt 1887 and 1999 of isolate R-CMV (subgroup II), with notable differences within SLM and SLL between the two strands. Mutati

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Dubois, Sigrid P., Milos D. Miljkovic, Thomas A. Fleisher, et al. "Short-course IL-15 given as a continuous infusion led to a massive expansion of effective NK cells: implications for combination therapy with antitumor antibodies." Journal for ImmunoTherapy of Cancer 9, no. 4 (2021): e002193. http://dx.doi.org/10.1136/jitc-2020-002193.

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BackgroundFull application of cytokines as oncoimmunotherapeutics requires identification of optimal regimens. Our initial effort with intravenous bolus recombinant human interleukin-15 (rhIL-15) was limited by postinfusional reactions. Subcutaneous injection and continuous intravenous infusion for 10 days (CIV-10) provided rhIL-15 with less toxicity with CIV-10 giving the best increases in CD8+ lymphocytes and natural killer (NK) cells. To ease rhIL-15 administration, we shortened time of infusion. Treatment with rhIL-15 at a dose of 3–5 µg/kg as a 5-day continuous intravenous infusion (CIV-5

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Cativiela, Carlos, JosÉ Ignacio García, Jean-Pierre Fayet, and JosÉ Elguero. "STUDIES IN THE AZOLE SERIES. CIV.1 EXPERIMETAL AND CALCULATED DIPOLE MOMENTS OF 3(5)-PHENYLPYPRAZOLES." Bulletin des Sociétés Chimiques Belges 104, no. 6 (2010): 383–86. http://dx.doi.org/10.1002/bscb.19951040604.

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Chon, W. James, Pradeep V. Kadambi, Chang Xu, et al. "Use of Leflunomide in Renal Transplant Recipients with Ganciclovir-Resistant/Refractory Cytomegalovirus Infection: A Case Series from the University of Chicago." Case Reports in Nephrology and Dialysis 5, no. 1 (2015): 96–105. http://dx.doi.org/10.1159/000381470.

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Introduction: Although antiviral prophylaxis for cytomegalovirus (CMV) is widely used, CMV infection remains common in renal transplant recipients with adverse consequences. Methods: We report 5 cases of renal transplant recipients with resistant CMV infection who were successfully managed with leflunomide at the University of Chicago Medical Center. Results: Five renal transplant recipients (2 simultaneous pancreas/kidney transplants, 3 deceased donor kidney transplants) were diagnosed with GCV-resistant CMV infection from 2003 to 2011. Of the 4 patients who had resistance genotype testing, 3

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Cong, P., V. Pricolo, P. Biancani, and J. Behar. "Effects of cholesterol on CCK-1 receptors and caveolin-3 proteins recycling in human gallbladder muscle." American Journal of Physiology-Gastrointestinal and Liver Physiology 299, no. 3 (2010): G742—G750. http://dx.doi.org/10.1152/ajpgi.00064.2010.

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The contraction of gallbladders (GBs) with cholesterol stones is impaired due to high cholesterol concentrations in caveolae compared with GBs with pigment stones. The reduced contraction is caused by a lower cholecystokinin (CCK)-8 binding to CCK-1 receptors (CCK-1R) due to caveolar sequestration of receptors. We aimed to examine the mechanism of cholesterol-induced sequestration of receptors. Muscle cells from human and guinea pig GBs were studied. Antibodies were used to examine CCK-1R, antigens of early and recycling endosomes, and total (CAV-3) and phosphorylated caveolar-3 protein (pCAV-

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Hooks, Michael A., Carl A. Perlino, J. Michael Henderson, William J. Millikan, and Michael H. Kutner. "Prevalence of Invasive Cytomegalovirus Disease with Administration of Muromonab Cd-3 in Patients Undergoing Orthotopic Liver Transplantation." Annals of Pharmacotherapy 26, no. 5 (1992): 617–20. http://dx.doi.org/10.1177/106002809202600501.

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OBJECTIVE: To assess the association of cytomegalovirus (CMV) disease with the administration of muromonab CD-3 (OKT-3) in patients undergoing liver transplant; specifically, to assess the risk of OKT-3 use as an agent for rejection prophylaxis and as an agent for therapy of rejection. DESIGN: Retrospective review of medical records. STUDY POPULATION: 83 liver transplant recipients (43 men, 40 women) with a mean age of 41.5 years (range 16–62). DATA EXTRACTION: The medical record for each liver transplant recipient was reviewed and analyzed for the following variables: (1) preoperative recipie

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Chen, Yun, Kuaile Zhao, Jingjun Ye, et al. "Safety results of a phase 3 study of comparing paclitaxel plus 5-fluorouracil versus cisplatin plus 5-fluorouracil in chemoradiotherapy for locally advanced esophageal carcinoma (ESO-Shanghai 1)." Journal of Clinical Oncology 35, no. 15_suppl (2017): 4066. http://dx.doi.org/10.1200/jco.2017.35.15_suppl.4066.

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4066 Background: Concurrent chemoradiotherapy (CCR) with cisplatin plus 5-Fu (PF) regimen is the standard modality for inoperable locally advanced esophageal squamous cell carcinoma (ESCC) patients. In this phase 3 trial, we aimed to assess the efficacy and safety of the paclitaxel plus 5-Fu (TF) regimen versus PF regimen in CCR for ESCC patients. Methods: ESCC patients presented with stage IIa to IVa were enrolled in a prospective multicenter phase 3 study. Patients were randomized to either PF group or TF group. Patients in PF group were treated with 2 cycles of CCR followed by 2 cycles of c

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Ivashchenko, Andrey A., Valeria N. Azarova, Alina N. Egorova, et al. "Effect of Aprotinin and Avifavir® Combination Therapy for Moderate COVID-19 Patients." Viruses 13, no. 7 (2021): 1253. http://dx.doi.org/10.3390/v13071253.

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COVID-19 is a contagious multisystem inflammatory disease caused by a severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). We studied the efficacy of Aprotinin (nonspecific serine proteases inhibitor) in combination with Avifavir® or Hydroxychloroquine (HCQ) drugs, which are recommended by the Russian Ministry of Health for the treatment therapy of moderate COVID-19 patients. This prospective single-center study included participants with moderate COVID-19-related pneumonia, laboratory-confirmed SARS-CoV-2, and admitted to the hospitals. Patients received combinations of intravenous (

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Ivanov, Ivan S., Nikolay I. Popov, Rumyana I. Moshe, et al. "Prevalence of Cytomegalovirus Infection in Hospitalized Infants." Folia Medica 54, no. 4 (2012): 45–52. http://dx.doi.org/10.2478/v10153-012-0005-5.

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Abstract Data on cytomegalovirus infection (CMV) prevalence and course in hospitalized infants are rather scarce, obsolete and considerably inconsistent. AIM: to determine the prevalence, rate of clinical manifestations, risk factors and predictive capacity of clinical manifestations of CMV infection in hospitalized infants during their first year of life. PATIENTS AND METHODS: All 163 infants hospitalized in the Pediatric Ward for Nonrespiratory Pathology in a tertiary hospital were serologically screened for cytomegalovirus infection for 10 months. In infants up to 6 months old that were CMV

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Kearse, Lee A., Carl Rosow, Alan Zaslavsky, Patricia Connors, Mark Dershwitz, and William Denman. "Bispectral Analysis of the Electroencephalogram Predicts Conscious Processing of Information during Propofol Sedation and Hypnosis." Anesthesiology 88, no. 1 (1998): 25–34. http://dx.doi.org/10.1097/00000542-199801000-00007.

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Background The bispectral index (BIS) measures changes in the interfrequency coupling of the electroencephalogram (EEG). The purposes of this study were (1) to determine whether BIS correlates with responses to command during sedation and hypnosis induced by propofol or propofol and nitrous oxide, and (2) to compare BIS to targeted and measured concentrations of propofol in predicting participants' responses to commands. Methods Twenty volunteers (15 men and 5 women, aged 22-50 yr) were given propofol by computer-controlled infusion, and EEG was recorded for off-line analysis of BIS. Responses

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Arun, PV Parvati Sai, Razak Hussain, Yusuf Akhter, Mandava Venkata Basaveswara Rao, Perugu Shyam, and Sailu Yellaboina. "Drug Re-purposing from SARS-CoV Led the Identification of Potential Candidate Drug Target and Alternate Drug Molecules Against SARSCoV- 2." Letters in Drug Design & Discovery 17, no. 10 (2020): 1325–27. http://dx.doi.org/10.2174/1570180817999200730190600.

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Background: SARS-CoV-2 causes COVID19 disease where there are no suitable drugs available. Objective: The objective of the work is to repurpose the drugs prescribed for SARS-CoV as the drugs for the control of SARS-CoV-2. Methods:: In this work, we have used homology searches and docking methods for understanding the mechanism of the drugs prescribed for the control of SARS-CoV on SARS-CoV-2. Results: In our analysis, we found that the drugs Benzyl (2-Oxopropyl)carbamate, 2-[(2,4-Dichloro- 5-methyl phenyl)sulfonyl]-1,3-dinitro-5-(trifluoromethyl)benzene, S-[5-(Trifluoromethyl)-4H-1,2,4- triazo

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Shehata, Mahmoud M., Ahmed Kandeil, Ahmed Mostafa, et al. "A Recombinant Influenza A/H1N1 Carrying A Short Immunogenic Peptide of MERS-CoV as Bivalent Vaccine in BALB/c Mice." Pathogens 8, no. 4 (2019): 281. http://dx.doi.org/10.3390/pathogens8040281.

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Middle East Respiratory Syndrome Coronavirus (MERS-CoV) became a global human health threat since its first documentation in humans in 2012. An efficient vaccine for the prophylaxis of humans in hotspots of the infection (e.g., Saudi Arabia) is necessary but no commercial vaccines are yet approved. In this study, a chimeric DNA construct was designed to encode an influenza A/H1N1 NA protein which is flanking immunogenic amino acids (aa) 736–761 of MERS-CoV spike protein. Using the generated chimeric construct, a novel recombinant vaccine strain against pandemic influenza A virus (H1N1pdm09) an

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Chiu, Wei-Wei, Richard M. Kinney, and Theo W. Dreher. "Control of Translation by the 5′- and 3′-Terminal Regions of the Dengue Virus Genome." Journal of Virology 79, no. 13 (2005): 8303–15. http://dx.doi.org/10.1128/jvi.79.13.8303-8315.2005.

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ABSTRACT The genomic RNAs of flaviviruses such as dengue virus (DEN) have a 5′ m7GpppN cap like those of cellular mRNAs but lack a 3′ poly(A) tail. We have studied the contributions to translational expression of 5′- and 3′-terminal regions of the DEN serotype 2 genome by using luciferase reporter mRNAs transfected into Vero cells. DCLD RNA contained the entire DEN 5′ and 3′ untranslated regions (UTRs), as well as the first 36 codons of the capsid coding region fused to the luciferase reporter gene. Capped DCLD RNA was as efficiently translated in Vero cells as capped GLGpA RNA, a reporter wit

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