Academic literature on the topic 'Culture cellulaire 4D'

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Journal articles on the topic "Culture cellulaire 4D"

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Burgstaller, Gerald, Sarah Vierkotten, Michael Lindner, Melanie Königshoff, and Oliver Eickelberg. "Multidimensional immunolabeling and 4D time-lapse imaging of vital ex vivo lung tissue." American Journal of Physiology-Lung Cellular and Molecular Physiology 309, no. 4 (2015): L323—L332. http://dx.doi.org/10.1152/ajplung.00061.2015.

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During the last decades, the study of cell behavior was largely accomplished in uncoated or extracellular matrix (ECM)-coated plastic dishes. To date, considerable cell biological efforts have tried to model in vitro the natural microenvironment found in vivo. For the lung, explants cultured ex vivo as lung tissue cultures (LTCs) provide a three-dimensional (3D) tissue model containing all cells in their natural microenvironment. Techniques for assessing the dynamic live interaction between ECM and cellular tissue components, however, are still missing. Here, we describe specific multidimensio
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Zheng, Yijun, Mitchell Kim Liong Han, Qiyang Jiang, Bin Li, Jun Feng, and Aránzazu del Campo. "4D hydrogel for dynamic cell culture with orthogonal, wavelength-dependent mechanical and biochemical cues." Materials Horizons 7, no. 1 (2020): 111–16. http://dx.doi.org/10.1039/c9mh00665f.

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Serchi, T., S. G. Klein, A. Jehanno, et al. "A 4D lung multi-culture system which mimicking alveolar cellular organization to study the toxic potential of airborne particles." Toxicology Letters 221 (August 2013): S183. http://dx.doi.org/10.1016/j.toxlet.2013.05.414.

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Sukparangsi, W., R. Bootsri, W. Sikeao, S. Karoon, and A. Thongphakdee. "181 Establishment of Induced Pluripotent Stem Cells from Fishing Cat and Clouded Leopard Using Integration-Free Method for Wildlife Conservation." Reproduction, Fertility and Development 30, no. 1 (2018): 230. http://dx.doi.org/10.1071/rdv30n1ab181.

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Fishing cat (Prionailurus viverrinus) and clouded leopard (Neofelis nebulosa) are wild felids, currently in vulnerable status according to the International Union for Conservation of Nature red list (2017). Several measures in assisted reproductive technology (e.g. AI, embryo transfer) have been used by the Zoological Park Organization of Thailand (ZPO) to increase their offspring in captivity. Recently, the generation of induced pluripotent stem cell (iPS cells) becomes popular and provides alternative way to preserve good genetics in the form of cell with diverse capacities. This great poten
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Górnicki, Tomasz, Jakub Lambrinow, Afsaneh Golkar-Narenji, et al. "Biomimetic Scaffolds—A Novel Approach to Three Dimensional Cell Culture Techniques for Potential Implementation in Tissue Engineering." Nanomaterials 14, no. 6 (2024): 531. http://dx.doi.org/10.3390/nano14060531.

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Biomimetic scaffolds imitate native tissue and can take a multidimensional form. They are biocompatible and can influence cellular metabolism, making them attractive bioengineering platforms. The use of biomimetic scaffolds adds complexity to traditional cell cultivation methods. The most commonly used technique involves cultivating cells on a flat surface in a two-dimensional format due to its simplicity. A three-dimensional (3D) format can provide a microenvironment for surrounding cells. There are two main techniques for obtaining 3D structures based on the presence of scaffolding. Scaffold
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Leppert, Jan, Jochen Krajewski, Sven Rainer Kantelhardt, et al. "Multiphoton Excitation of Autofluorescence for Microscopy of Glioma Tissue." Neurosurgery 58, no. 4 (2006): 759–67. http://dx.doi.org/10.1227/01.neu.0000204885.45644.22.

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Abstract OBJECTIVE: Intraoperative detection of residual tumor tissue in glioma surgery remains an important challenge because the extent of tumor removal is related to the prognosis of the disease. Multiphoton excited fluorescence tomography of living tissues provides high-resolution structural and photochemical imaging at a subcellular level. In this conceptual study, we have used multiphoton microscopy and fluorescence lifetime imaging (4D microscopy) to image cultured glioma cell lines, solid tumor, and invasive tumor cells in an experimental mouse glioma model and human glioma biopsy spec
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Soper, Brian W., Mark D. Lessard, Travis L. Alley, Jennifer L. Proctor, Anthony J. Mourino, and Jane E. Barker. "Treatment of Neurological Dysfunction in MPS VII and Batten Disease by Transplantation of Lentivirally Transduced Neuronal Stem Cells Cultured from Hematopoietic Tissue." Blood 106, no. 11 (2005): 1284. http://dx.doi.org/10.1182/blood.v106.11.1284.1284.

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Abstract The subventricular zone (SVZ) of lateral ventricles in brain contains neuronal stem cells (NSC) that form neurospheres when cultured with EGF and/or bFGF. Progeny from transplanted NSC migrate throughout the brain and replace multiple differentiated cells. Our goal is to develop this phenomenon into a cellular/gene therapeutic approach for treatment of neurological disease. Progeny of normal or gene transduced NSC can replace defective host cells or act as enzyme delivery vehicles. One model for testing this approach is the Mucopolysaccharidosis Type VII (MPS VII) mouse that is defici
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Zehender, A., Y. N. Li, N. Y. Lin, et al. "AB0091 INHIBITION OF AUTOPHAGY PREVENTS PROGRESSION OF FIBROSIS IN MURINE MODELS OF SYSTEMIC SCLEROSIS." Annals of the Rheumatic Diseases 80, Suppl 1 (2021): 1075.3–1075. http://dx.doi.org/10.1136/annrheumdis-2021-eular.819.

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Background:Autophagy is catabolic process allowing cells to degrade unnecessary or dysfunctional cellular organelles. Failure of appropriate regulation of autophagy, however, can severely perturb tissue homeostasis. Recent studies demonstrate that autophagy is activated in several fibrotic diseases such as liver fibrosis, renal interstitial fibrosis, cardiac fibrosis.Objectives:The objective of this work was to characterize the activation of autophagy in systemic sclerosis (SSc) and to decipher its role in the pathogenesis of SSc.Methods:Activation of autophagy in skin samples of patients and
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Hose, Dirk, Anja Seckinger, Hartmut Goldschmidt, et al. "A Novel Class of Sulfonanilides Entering Clinical Trials for Targeted Treatment of Multiple Myeloma: Dual-Mechanism Compounds Inhibiting HIF1A-Signaling and Inducing Apoptosis." Blood 116, no. 21 (2010): 2987. http://dx.doi.org/10.1182/blood.v116.21.2987.2987.

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Abstract Abstract 2987 Background. We have recently shown HIF1A to be expressed in 95.4% of CD138-purified myeloma cell samples from previously untreated patients (n= 329), with significantly higher [lower] expression in case of presence of t(4,14) [hyperdiploidy] vs. patients without the respective aberration. This makes HIF1A an interesting target in myeloma treatment. Additionally, we have shown about 40% of myeloma cell samples to have a proliferation-index above the median plus three standard-deviations of normal bone-marrow plasma cells, and we and others have proven proliferation to be
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Shen, L., Y. Zhang, Z. Honglin та J. H. W. Distler. "POS0476 THE NUCLEAR RECEPTOR TR4 ORCHESTRATES CYTOSKELETAL ORGANIZATION IN A Gα12/ROCK-DEPENDENT MANNER TO PROMOTE MYOFIBROBLAST DIFFERENTIATION AND TISSUE FIBROSIS IN SYSTEMIC SCLEROSIS". Annals of the Rheumatic Diseases 81, Suppl 1 (2022): 492.2–493. http://dx.doi.org/10.1136/annrheumdis-2022-eular.2033.

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BackgroundNuclear receptors (NR) are a family of transcription factors. Several members of the NR family are candidates for targeted intervention in inflammatory and fibrotic diseases (1-2). Testicular receptor 4 (TR4), also known as Nr2c2, has been shown to regulate fundamental cellular processes such as differentiation, proliferation and growth factor signaling (3-4). However, its role in fibrotic diseases has not been investigated so far.ObjectivesThe aim of the present study was to characterize the role of TR4 in the pathogenesis of fibrotic tissue remodeling in SSc and to interrogate its
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Dissertations / Theses on the topic "Culture cellulaire 4D"

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Hahn, Franziska. "Échafaudages microporeux et électroactifs 4D comme plateforme innovante de culture cellulaire." Electronic Thesis or Diss., CY Cergy Paris Université, 2024. http://www.theses.fr/2024CYUN1333.

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In vivo, les cellules sont situées dans un microenvironnement poreux et dynamique en 3D qui fournit des signaux biochimiques et biophysiques ainsi que des signaux dynamiques influençant le comportement des cellules dans des contextes physiologiques et pathologiques. Afin de mieux reproduire ces conditions in vitro pour des applications en biologie cellulaire fondamentale, en ingénierie tissulaire et en dépistage de médicaments, cette thèse présente le développement d'échafaudages 4D électro-actifs, combinant une architecture 3D passive et microporeuse nommée polyHIPE et un polymère électroacti
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Conference papers on the topic "Culture cellulaire 4D"

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Mishra, Dhruva Kumar, Michael J. Thrall, Jonathan M. Kurie, and Min P. Kim. "Abstract B31: Lung fibroblast enhances MMP-1 secretion when co-cultured with human lung cancer cells in the 4D lung cancer model." In Abstracts: AACR Special Conference on Cellular Heterogeneity in the Tumor Microenvironment; February 26 — March 1, 2014; San Diego, CA. American Association for Cancer Research, 2015. http://dx.doi.org/10.1158/1538-7445.chtme14-b31.

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