Academic literature on the topic 'Cumulative Population Doubling Level'

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Journal articles on the topic "Cumulative Population Doubling Level"

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Fung, Isaac Chun-Hai, Xiaolu Zhou, Chi-Ngai Cheung, et al. "Assessing Early Heterogeneity in Doubling Times of the COVID-19 Epidemic across Prefectures in Mainland China, January–February, 2020." Epidemiologia 2, no. 1 (2021): 95–113. http://dx.doi.org/10.3390/epidemiologia2010009.

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To describe the geographical heterogeneity of COVID-19 across prefectures in mainland China, we estimated doubling times from daily time series of the cumulative case count between 24 January and 24 February 2020. We analyzed the prefecture-level COVID-19 case burden using linear regression models and used the local Moran’s I to test for spatial autocorrelation and clustering. Four hundred prefectures (~98% population) had at least one COVID-19 case and 39 prefectures had zero cases by 24 February 2020. Excluding Wuhan and those prefectures where there was only one case or none, 76 (17.3% of 4
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Sun, Yi, Annette Nold, Ulrich Glitsch, and Frank Bochmann. "Exposure–Response Relationship and Doubling Risk Doses—A Systematic Review of Occupational Workload and Osteoarthritis of the Hip." International Journal of Environmental Research and Public Health 16, no. 19 (2019): 3681. http://dx.doi.org/10.3390/ijerph16193681.

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In this review, we critically evaluated the evidence of exposure–response relationships between occupational workload and the risk of hip osteoarthritis. The existing evidence was evaluated in order for us to extrapolate possible doubling risk doses for hip osteoarthritis. Comprehensive searches for epidemiological studies of hip osteoarthritis and occupational workload were performed in literature databases (PubMed, EMBASE, Cochrane Work and Google Scholar) and recent reviews up to February 2019. In total, 85 papers met the preliminary inclusion criteria, and 10 studies indicating an exposure
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Turner, D. A., and R. Brightwell. "An evaluation of a sequential aerial spraying operation against Glossina pallidipes Austen (Diptera: Glossinidae) in the Lambwe Valley of Kenya: aspects of post-spray recovery and evidence of natural population regulation." Bulletin of Entomological Research 76, no. 2 (1986): 331–49. http://dx.doi.org/10.1017/s0007485300014802.

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AbstractAn attempt to eradicate Glossina pallidipes Austen from the Lambwe Valley of western Kenya by sequential aerial application of endosulfan aerosol spray is described. The operation was ultimately unsuccessful, even after nine sprays of relatively heavy dosages of insecticide. Survivors were present throughout after each spray, and females mated and bred between sprays. The population was reduced by over 99·9% in main habitats of thicket and woodland and by about 90% in conifer plantation. The outcome of a model of spray effectiveness suggested, however, that the final reduction in popul
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Salvatore, Maxwell, Deepankar Basu, Debashree Ray, et al. "Comprehensive public health evaluation of lockdown as a non-pharmaceutical intervention on COVID-19 spread in India: national trends masking state-level variations." BMJ Open 10, no. 12 (2020): e041778. http://dx.doi.org/10.1136/bmjopen-2020-041778.

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ObjectivesTo evaluate the effect of four-phase national lockdown from March 25 to May 31 in response to the COVID-19 pandemic in India and unmask the state-wise variations in terms of multiple public health metrics.DesignCohort study (daily time series of case counts).SettingObservational and population based.ParticipantsConfirmed COVID-19 cases nationally and across 20 states that accounted for >99% of the current cumulative case counts in India until 31 May 2020.ExposureLockdown (non-medical intervention).Main outcomes and measuresWe illustrate the masking of state-level trends and highli
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Seo, Min-Soo, Kyung-Ku Kang, Se-Kyung Oh, et al. "Isolation and Characterization of Feline Wharton’s Jelly-Derived Mesenchymal Stem Cells." Veterinary Sciences 8, no. 2 (2021): 24. http://dx.doi.org/10.3390/vetsci8020024.

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Wharton’s jelly is a well-known mesenchymal stem cell source in many species, including humans. However, there have been no reports confirming the presence of mesenchymal stem cells in Wharton’s jelly in cats. The purpose of this study was to isolate mesenchymal stem cells (MSCs) from the Wharton’s jelly of cats and to characterize stem cells. In this study, feline Wharton’s jelly-derived mesenchymal stem cells (fWJ-MSCs) were isolated and successfully cultured. fWJ-MSCs were maintained and the proliferative potential was measured by cumulative population doubling level (CPDL) test, scratch te
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Chang, Yu Sang, Byong-Jin You, and Hann Earl Kim. "Dynamic Trends of Fine Particulate Matter Exposure across 190 Countries: Analysis and Key Insights." Sustainability 12, no. 7 (2020): 2910. http://dx.doi.org/10.3390/su12072910.

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Despite the fact that fine particulate matter (PM2.5) causes serious health issues, few studies have investigated the level and annual rate of PM2.5 change across a large number of countries. For a better understanding of the global trend of PM2.5, this study classified 190 countries into groups showing different trends of PM2.5 change during the 2000–2014 period by estimating the progress ratio (PR) from the experience curve (EC), with PM2.5 exposure (PME)–the population-weighted average annual concentration of PM2.5 to which a person is exposed—as the dependent variable and the cumulative en
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Keizman, Daniel, Moshe A. Frenkel, Avivit Peer, et al. "Effect of pectasol-c modified citrus pectin (P-MCP) treatment (tx) on PSA dynamics in non-metastatic biochemically relapsed prostate cancer (BRPC) patients (pts): Results of a prospective phase II study." Journal of Clinical Oncology 36, no. 6_suppl (2018): 14. http://dx.doi.org/10.1200/jco.2018.36.6_suppl.14.

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14 Background: 30% of pts with localized PC will have a biochemical relapse post local tx. The optimal tx of these pts remains elusive. While androgen deprivation therapy is effective in reducing PSA level, its long-term benefit on survival remain undefined, and it is associated with significant cumulative toxicities.Thus, evaluation of new non-toxic compounds in this pt population is warranted. P-MCP is a competitive inhibitor of galectin-3, a carbohydrate-binding protein, which is known to be involved in cancer pathogenesis. Pre-clinical and clinical data suggest that P-MCP is active in PC.
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Houben, Amelie Pia, Anja Buchheiser, Murat Aktas, Johannes Fischer, Peter Wernet, and Gesine Koegler. "Age-Related Differences Between Unrestricted Somatic Stem Cells from Cord Blood and Bone Marrow Derived Mesenchymal Stroma Cells." Blood 112, no. 11 (2008): 1335. http://dx.doi.org/10.1182/blood.v112.11.1335.1335.

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Abstract During the past years haematopoietic stem cells from unrelated umbilical cord blood have been increasingly used for treatment of leukaemia and genetic diseases. Human cord blood also contains a non-haematopoietic, adherently growing, CD45 negative, Oct4, nanog and Sox2 negative cell population with intrinsic multipotent differentiation potential, described as Unrestricted Somatic Stem Cells (USSC) (Kögler et al. 2004, Kögler et al. 2005, Kögler et al. 2006, Sensken et al. 2007, Liedtke et al. 2007, Liedtke et al.2008, Greschat et al. 2008, Ghodsizad A et al. 2008, Trapp et al. 2008
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Keizman, Daniel, Moshe A. Frenkel, Todd Michael Edwards, et al. "Effect of PectaSol-C modified citrus pectin (P-MCP) treatment (tx) on PSA dynamics in patients (pts) with nonmetastatic, biochemically relapsed prostate cancer (BRPC): Results of the interim analysis of a prospective phase II study." Journal of Clinical Oncology 35, no. 15_suppl (2017): e16588-e16588. http://dx.doi.org/10.1200/jco.2017.35.15_suppl.e16588.

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e16588 Background: 30% of pts with localized PC will have a biochemical relapse post local tx. The optimal tx of these pts remains elusive. While androgen deprivation therapy is effective in reducing PSA level, its long term benefit on survival remain undefined, and it is associated with significant cumulative toxicities.Thus evaluation of new non-toxic compounds in this pt population is warranted. P-MCP is a competitive inhibitor of galectin-3, a carbohydrate-binding protein, which is known to be involved in cancer pathogenesis. Preliminary pre-clinical and clinical data suggest that P-MCP is
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Ang, A. H., G. Tachas, J. H. Campbell, J. F. Bateman, and G. R. Campbell. "Collagen synthesis by cultured rabbit aortic smooth-muscle cells. Alteration with phenotype." Biochemical Journal 265, no. 2 (1990): 461–69. http://dx.doi.org/10.1042/bj2650461.

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Enzymically isolated rabbit aortic smooth-muscle cells (SMC) in the first few days of primary culture express a ‘contractile phenotype’, but with time these cells modulate to a ‘synthetic phenotype’. Synthetic-state SMC are able to proliferate, and, provided that they undergo fewer than 5 cumulative population doublings, return to the contractile phenotype after reaching confluency [Campbell, Kocher, Skalli, Gabbiani & Campbell (1989) Arteriosclerosis 9, 633-643]. The present study has determined the synthesis of collagen, at the protein and mRNA levels, by cultured SMC as they undergo a c
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Dissertations / Theses on the topic "Cumulative Population Doubling Level"

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Streit, Susanne. "Die Untersuchung der replikativen Seneszenz kaniner dermaler Fibroblasten als Beitrag zur Alternsforschung." Doctoral thesis, [S.l.] : [s.n.], 2006. http://deposit.ddb.de/cgi-bin/dokserv?idn=982864698.

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Streit, Susanne. "Die Untersuchung der replikativen Seneszenz kaniner dermaler Fibroblasten als Beitrag zur Alternsforschung." Doctoral thesis, 2005. https://ul.qucosa.de/id/qucosa%3A10631.

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Mit der vorliegenden Arbeit sollte nachgewiesen werden, dass bei in vitro kultivierten kaninen dermalen Fibroblasten einer Hunderasse nach einer bestimmte Kultivierungszeit replikative Seneszenz entsteht und dass das replikative Vermögen dieser Zellen in der Zellkultur abhängig vom Alter des Spendertieres ist. Dreißig Beagle aus zwei Versuchstieranstalten wurden als Hautspender genutzt. Diese Tiere wurden in die drei Altersgruppen jung, adult und alt unterteilt. Mit Hilfe einer Hautstanze wurde bei allen Tieren im Bereich der rechten Skapula ein Hautstück gewonnen. Diese Hautstücken wurden in
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Book chapters on the topic "Cumulative Population Doubling Level"

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"Challenges for Diadromous Fishes in a Dynamic Global Environment." In Challenges for Diadromous Fishes in a Dynamic Global Environment, edited by Rob MacGregor, John M. Casselman, William A. Allen, et al. American Fisheries Society, 2009. http://dx.doi.org/10.47886/9781934874080.ch45.

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<em>Abstract</em>.-We examine historical, archaeological, and current patterns in American eel <em>Anguilla rostrata </em>use, abundance, and distribution to improve understanding of current population- level status. Our research indicates that distribution and abundance has changed significantly in response to the cumulative impacts of fishing, turbine mortality, and major loss of freshwater habitat. The 1950-1970 peaks in dam construction and turbine mortalities, together with the unprecedented North American harvests in the 1970s, have lead to a perilous synergy of effects at the population level. Based on our findings, we call for coordinated conservation and management actions for American eel across North America. Preservation of life cycle diversity and coordinated conservation actions are required across the range to ensure continued and improved societal benefits, protect the legacy of cultural and natural heritage values, restore ecological services, and reinstate the benefits to biodiversity provided by this unique and important species. Finally, we describe key elements and recent progress in recovery planning.
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Keshari, Puneshwar. "Controversy, Adulteration and Substitution: Burning Problems in Ayurveda Practices." In Pharmacognosy - Medicinal Plants [Working Title]. IntechOpen, 2021. http://dx.doi.org/10.5772/intechopen.98220.

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Ayurveda is an Indian traditional system of medicine. In present era, world is looking towards herbal medicine because of acceptability and safety. Medicinal plants constitute an effective source of Ayurvedic and other traditional system of medicines as well as modern medicine. In India, about 80% of the rural population depends on herbal medicines in primary health care level. A large percentage of plants used in herbal industries are subject of controversy. Non-availability of plants, poor understanding and parallel evolved knowledge systems are some of the reasons attributed to it. The existing practices of polynomial nomenclature system of Sanskrit, different perceptions in various communities, vernacular equivalents, all are cumulative factors for controversy, adulteration and substitution. “ Sandigdha Dravaya “ is a term used for that type of medicinal plants which are mentioned in Ayurvedic classics but their exact botanical source is not known. Adulterants and substitutes are the common practices in herbal raw material trade. Adulteration is a debasement of an article. The motives for intentional adulteration are normally commercial that which involves deterioration, admixture, sophistication, inferiority, spoilage and other unknown reasons. Substitution is a replacement of equivalent drugs in place of original drugs. The principles to select substitute drugs are based on similar Rasa, Guna, Virya, Vipaka and mainly the Karma. At present the adulteration and Substitution of the herbal drugs is the burning problem in herbal industry and in Ayurvedic practices. So it is necessary to develop reliable methodologies for correct identification, standardization and quality assurance of Ayurvedic drugs.
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Burgess, Stephen, Carmine Carmine Sellitto, and Stan Karanasios. "A Look at the Future." In Effective Web Presence Solutions for Small Businesses. IGI Global, 2009. http://dx.doi.org/10.4018/978-1-60566-224-4.ch011.

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This chapter serves to raise an awareness of some of the more cutting edge Internet innovations and applications that may become viable and useful to the small business operator in future. The chapter focuses on some of the new and emerging forms of technologies that the authors have identified as potentially affecting the Web presence. Consequently, the topic areas and content examined in the chapter does not claim to be all encompassing or prescriptive. Some of the innovations examined are nascent and may not progress to a critical mass for general adoption, whilst others tend to be used by larger business entities, possibly requiring a re-configuration if they are to be successfully used in the small business environment. Arguably, many if not all would in some way impact on the business Web presence if they were to be adopted in future. An examination of the adoption and use of new forms of technology and ideas - or innovations as they are sometimes referred - can be assisted by examining how the early adopters use these innovations. This was briefly discussed in Chapter IV. The concept of innovation adoption and the importance of early adopters is well documented by Rogers (1995). The Rogers’ paradigm describes how innovations advance, or diffuse, through a population either to be adopted or to be rejected. The successful diffusion of an innovation generally follows the S-shaped rate of adoption when a cumulative curve is plotted. The cumulative S-shaped rate of adoption curve is depicted in Figure 1 showing the relationship between the adopters and late-adopters over a period of time. Generally, the adoption of the innovation by the early adopters results in an adoption curve that is reasonably flat. However, as more members of a business group adopt the innovation, the curve ‘takes off’, with the advent of late adopters signalling the innovation has diffused through that particular group. Clearly, for the small business operator an indicator of an innovation that may be associated with a Web presence can be closely allied in the identification of the early adopters. The early adopters are important in the diffusion process as opinion leaders - where potential adopters look to them for advice and information, as well as best practices to emulate. Moreover, the early adopters are considered to be the individuals to investigate or analyse before using a new idea, tending to serve as role models for many others. Early adopters can be deemed to be the most important constituent in the innovation-diffusion process because they decrease uncertainty about a new idea or technology, and as a consequence convey a message of acceptance and effectiveness to peers (Rogers 1995). According to Norman (1998), the early users of an innovation provide the experience for the late adopters to observe and to learn from. Norman further suggests that even though these early users are relatively few in number, they are the drivers of a technology and can provide examples of how and why that innovation can be used. Arguably, the small business operator by conducting an examination within their own industry for the specific use of new forms of Web-related technology will identify a set of industry early adopters from which they themselves can learn from. Small businesses have been known to be conservative in nature in relation to their use of ICTs, so many feel quite comfortable with the notion of waiting until the early adopters have been successful or otherwise. Of course, if the adoption has been successful they do not necessarily achieve the same level of benefits (often resulting in competitive advantage) that early adopters realise, but at the same time they are not taking the same risk with an unknown technology. Often, the late adopter is forced to adopt the technology as it has diffused through the majority of the industry as is regarded as a requirement by business partners or customers.
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Conference papers on the topic "Cumulative Population Doubling Level"

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Riyadina, Woro, Dewi Kristanti, Julianty Pradono, Ekowati Rahajeng, and Yuda Turana. "A Cohort Study on The Primary Prevention of Stroke Incidence in Adult Population in Bogor, West Java." In The 7th International Conference on Public Health 2020. Masters Program in Public Health, Universitas Sebelas Maret, 2020. http://dx.doi.org/10.26911/the7thicph.01.25.

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ABSTRACT Background: Incidence of stroke showed an increasing trend in Indonesia, 12 new cases per 1,000 in 2013, and 19 new cases per 1,000 in 2018 despite the stroke control programs from the government. This study aimed to estimate Cumulative Incidence, Incidence Rate, and Population Attributable Fraction (PAF). This study also estimated the effect of blood pressure, physical activity, blood sugar levels, and smoking habits on the risk of stroke in adults. Subjects and Method: This was a cohort study conducted for 6 years in 5 Districts, Bogor City, West Java. An adult population of 5,189 s
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Zurin, Eduard, Elena Petruk, and Elena Bobkova. "Identification of the Indicators Set for Characterizing Adults’ Motor Activity." In The Public/Private in Modern Civilization, the 22nd Russian Scientific-Practical Conference (with international participation) (Yekaterinburg, April 16-17, 2020). Liberal Arts University – University for Humanities, Yekaterinburg, 2020. http://dx.doi.org/10.35853/ufh-public/private-2020-65.

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The article considers a set of indicators characterising motor activity in the adult population, as the definition of motor activity indicators of physical fitness and sport (MA) is considered in regulatory documents with different values. The present study examined the population distribution of average daily physical activity during the year, the limits of variability in quantitative measures of weekly physical activity, and preferred forms of exercise among the 1855 year old population of the Russian Federation (40,145 persons, including 14,677 men and 25,468 women) using the ONETRAK ecosys
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Ciconkov, Risto. "Climate Change and HVACR Systems." In 50th International HVAC&R Congress and Exhibition. SMEITS, 2020. http://dx.doi.org/10.24094/kghk.019.50.1.245.

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Indicators at a global level are presented: population in the world today and forecasts for developed and developing countries. The following diagrams are presented: world total primary energy consumption, global CO2 emissions from combustion since 1971, as well as cumulative CO2 emissions by regions since 1750. Facts for climate change are included (according to WMO and IPCC): increase in GHG concentrations, increase in air temperature, rise in sea level, etc. The consequences of global warming are listed: extreme rainfall and floods; high temperatures – heat waves, droughts, wildfires; huge
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Twomey, Kelly M., and Michael E. Webber. "Evaluating the Energy Intensity of the US Public Water System." In ASME 2011 5th International Conference on Energy Sustainability. ASMEDC, 2011. http://dx.doi.org/10.1115/es2011-54165.

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Previous analyses have concluded that the United State’s water sector uses over 3% of national electricity consumption for the production, conveyance, and treatment of water and wastewater and as much as 10% when considering the energy required for on-site heating, cooling, pumping, and softening of water for end-use. The energy intensity of water is influenced by factors such as source water quality, its proximity to a water treatment facility and end-use, its intended end-use and sanitation level, as well as its conveyance to and treatment at a wastewater treatment facility. Since these requ
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Reports on the topic "Cumulative Population Doubling Level"

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Kartha, Sivan, Eric Kemp-Benedict, Emily Ghosh, Anna Nazareth, and Tim Gore. The Carbon Inequality Era: An assessment of the global distribution of consumption emissions among individuals from 1990 to 2015 and beyond. Oxfam, Stockholm Environment Institute, 2020. http://dx.doi.org/10.21201/2020.6492.

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In the 25 years from 1990 to 2015, annual global carbon emissions grew by 60%, approximately doubling total global cumulative emissions. This has brought the world perilously close to exceeding 2°C of warming, and it is now on the verge of exceeding 1.5°C. This paper examines the starkly different contributions of different income groups to carbon emissions in this period. It draws on new data that provides much improved insight into global and national income inequality, combined with national consumption emissions over this 25-year period, to provide an analysis relating emissions to income
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