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Journal articles on the topic 'Curative Therapy'

Author: Grafiati
Published: 2 June 2025
Last updated: 31 July 2025

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1

Nilsson, Sten, Gabriella Cohn-Cedermark, and Peter Wiklund. "Introduction: Therapy with curative intent." Acta Oncologica 50, sup1 (2011): 90–91. http://dx.doi.org/10.3109/0284186x.2010.576548.

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2

&NA;. "Curative gene therapy trial planned." Inpharma Weekly &NA;, no. 830 (1992): 10. http://dx.doi.org/10.2165/00128413-199208300-00019.

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3

Harmenberg, Ulrika, Freddie C. Hamdy, Anders Widmark, Bo Lennernäs, and Sten Nilsson. "Curative radiation therapy in prostate cancer." Acta Oncologica 50, sup1 (2011): 98–103. http://dx.doi.org/10.3109/0284186x.2010.576115.

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4

Rieker, P. P., S. D. Edbril, and M. B. Garnick. "Curative testis cancer therapy: psychosocial sequelae." Journal of Clinical Oncology 3, no. 8 (1985): 1117–26. http://dx.doi.org/10.1200/jco.1985.3.8.1117.

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We examined the long-term impact of advanced testis cancer and its curative therapies on emotional states and outlook on life, employment, intimate relationships, and sexual function. The sample consisted of 74 nonseminomatous and seminomatous tumor patients who had completed treatment two to ten years ago. The majority of men felt that surviving the debilitating treatment(s) was both an accomplishment and worthwhile trade-off. Neither the rate of unemployment (7%) nor divorce (10%) was remarkable. The most critical outcome was in the area of sexual functioning. One fourth to one half of the m
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5

Cooke, Ellen W., and Lisa Hazard. "Curative Radiation Therapy for Pancreatic Malignancies." Surgical Clinics of North America 90, no. 2 (2010): 341–54. http://dx.doi.org/10.1016/j.suc.2009.12.002.

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6

Fazio, Victor W. "Curative local therapy of rectal cancer." International Journal of Colorectal Disease 6, no. 2 (1991): 66–73. http://dx.doi.org/10.1007/bf00300193.

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7

Lim, Chae Hong, Soo Bin Park, Hong Kwan Kim, et al. "Clinical Value of Surveillance 18F-fluorodeoxyglucose PET/CT for Detecting Unsuspected Recurrence or Second Primary Cancer in Non-Small Cell Lung Cancer after Curative Therapy." Cancers 14, no. 3 (2022): 632. http://dx.doi.org/10.3390/cancers14030632.

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We evaluated the diagnostic value of 18F-fluorodeoxyglucose (FDG) positron emission tomography (PET)/CT surveillance for detecting clinically unsuspected recurrence or second primary cancer (SPC) in patients with non-small cell lung cancer (NSCLC) after curative therapy. A total of 4478 surveillance FDG PET/CT scans from 2864 NSCLC patients without suspicion of recurrence after curative therapy were reviewed retrospectively. In 274 of 2864 (9.6%) patients, recurrent NSCLC or SPC was found by surveillance PET/CT during clinical follow-up. Surveillance PET/CT scans showed sensitivity of 98.9% (2
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8

Möller, Miriam, and Wolfgang Schütte. "NSCLC im Stadium II: Strahlentherapie und Einsatz von Chemotherapie bei nicht operablen Patienten." Kompass Pneumologie 8, no. 3 (2020): 146–47. http://dx.doi.org/10.1159/000507834.

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Objectives: Curative intent therapy of stage II NSCLC may include surgical resection or definitive radiotherapy. Primary management with surgery or radiotherapy may be influenced by patient and disease characteristics. We sought to perform a comparison of patients receiving surgery or radical radiation therapy as their curative treatment, and explore the impact of known prognostic factors on outcome. Materials and methods: A retrospective review was completed of all patients with stage II NSCLC referred to the BC Cancer Agency from 2005 to 2012. Cases were filtered to identify those receiving
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9

Bartenschlager, Ralf, Stephan Urban, and Ulrike Protzer. "Towards curative therapy of chronic viral hepatitis." Zeitschrift für Gastroenterologie 57, no. 01 (2019): 61–73. http://dx.doi.org/10.1055/a-0824-1576.

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AbstractPersistent infection with hepatitis viruses is a major medical burden that unfortunately is often ignored in the general public. This results in a massive under-diagnosis of these infections. According to the world health organization, the number of people dying every year from the consequence of hepatitis virus infection has surpassed the death rate caused by malaria and HIV and is equivalent to the one of tuberculosis. These numbers call for more intense efforts to devise more effective, ideally curative therapies that must become as widely accessible as they are e. g. for HIV infect
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10

Gostecnik, Christian, Tanja Repic, and Robert Cvetek. "Potential Curative Space in Relational Family Therapy." Journal of Family Psychotherapy 20, no. 1 (2009): 46–59. http://dx.doi.org/10.1080/08975350802716491.

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11

Bhatia, S. K., A. C. Paulino, J. M. Ritchie, J. M. Buatti, N. A. Mayr, and B. C. Wen. "Curative radiation therapy for primary orbital lymphoma." International Journal of Radiation Oncology*Biology*Physics 51, no. 3 (2001): 360–61. http://dx.doi.org/10.1016/s0360-3016(01)02489-0.

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12

Wu, Christina, and Tanios Bekaii-Saab. "Adjuvant Therapy Following Curative Resection of Metastases." Current Colorectal Cancer Reports 8, no. 3 (2012): 217–24. http://dx.doi.org/10.1007/s11888-012-0130-9.

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13

Mubarakshina, Mubarakshina O. A., Dronova Yu M. Dronova, and Chernov S. Yu Chernov. "The role of potable curative mineral water in digestive system functions maintaining." Therapy 4_2024 (June 24, 2024): 165–72. http://dx.doi.org/10.18565/therapy.2024.4.165-172.

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14

Yuan, Peng, Peng Chen, and Yeben Qian. "Evaluation of Antiviral Therapy Performed after Curative Therapy in Patients with HBV-Related Hepatocellular Carcinoma: An Updated Meta-Analysis." Canadian Journal of Gastroenterology and Hepatology 2016 (2016): 1–11. http://dx.doi.org/10.1155/2016/5234969.

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Background.The long-term prognosis after curative therapy for hepatitis B virus- (HBV-) related hepatocellular carcinoma (HCC) remains unsatisfactory due to the high incidence of recurrence. The effect of treatment with nucleotide analogues (NAs) in patients with HBV-related HCC after curative therapy remains unclear.Objective.To assess the impact of using NAs after curative therapy.Method.A computerized literature search was performed; eligible studies were identified from databases. The pooled risk ratios (RRs) and 95% CIs were calculated using Review Manager 5.3.Result.The meta-analysis inc
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15

Keane, Thomas J. "Radiation Therapy of Carcinoma of the Esophagus." Canadian Journal of Gastroenterology 4, no. 9 (1990): 608–11. http://dx.doi.org/10.1155/1990/670301.

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Radical radiation therapy with curative intent for esophageal squamous carcinoma is used both as a single modality and combined with chemotherapy. Failure to eradicate disease at the primary tumour site represents the greatest cause of failure of curative radiotherapy. The aim of curative radiotherapy is to deliver the highest dose of radiation at the tumour site while minimizing radiation delivered to the surrounding tissues. The best survival results are obtained in patients with tumours less than 5 cm in length, confined to the upper one-third of the esophagus. Regular endoscopic examinatio
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16

Hata, Masaharu. "Radiation therapy for elderly patients with uterine cervical cancer: feasibility of curative treatment." International Journal of Gynecologic Cancer 29, no. 3 (2019): 622–29. http://dx.doi.org/10.1136/ijgc-2018-000077.

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As the average lifespan lengthens worldwide, and the older adult population increases, the number of elderly patients with uterine cervical cancer is increasing. Because intensive and invasive treatments, including surgery, are frequently unacceptable in elderly patients, cancer treatments for these patients must be carefully considered. Elderly patients have undergone radiation therapy as less-invasive curative treatment, and it has been shown to be safe and effective for local control of cervical cancer in this population, even among patients aged ≥80 years treated with curative radiation do
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17

Himanshi, Shrivastava* Priyal Jain Dr. Jitendra Banweer. "Curative Therapy: Impact on Family Care and Society." International Journal of Pharmaceutical Sciences 3, no. 5 (2025): 3372–95. https://doi.org/10.5281/zenodo.15472421.

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Curative therapy represents a significant advancement in modern medicine, aiming to completely eliminate diseases rather than merely managing their symptoms. Unlike palliative care, which focuses on symptom relief and improving the quality of life, curative therapy strives to address the root cause of illness to restore full health. This distinction marks a transformative shift in how chronic and life-threatening conditions are approached. With ongoing innovations in gene therapy, personalized medicine, targeted drug regimens, and minimally invasive surgical procedures, curative therapies are
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18

Kassim, Adetola A., and Alexis Leonard. "Debating the Future of Sickle Cell Disease Curative Therapy: Haploidentical Hematopoietic Stem Cell Transplantation vs. Gene Therapy." Journal of Clinical Medicine 11, no. 16 (2022): 4775. http://dx.doi.org/10.3390/jcm11164775.

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Hematopoietic stem cell transplantation (HSCT) is a well-established curative therapy for patients with sickle cell disease (SCD) when using a human leukocyte antigen (HLA)-matched sibling donor. Most patients with SCD do not have a matched sibling donor, thereby significantly limiting the accessibility of this curative option to most patients. HLA-haploidentical HSCT with post-transplant cyclophosphamide expands the donor pool, with current approaches now demonstrating high overall survival, reduced toxicity, and an effective reduction in acute and chronic graft-vs.-host disease (GvHD). Alter
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19

Goetze, Thorsten Oliver, and Salah-Eddin Al-Batran. "Perspectives on the Management of Oligometastatic Disease in Esophago-Gastric Cancer." Cancers 14, no. 21 (2022): 5200. http://dx.doi.org/10.3390/cancers14215200.

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Gastric adenocarcinoma and esophageal cancer are the fifth and seventh most common cancer types worldwide. At the time of initial diagnosis, up to 50% of esophagogastric cancers present with distant metastatic lesions and are candidates for chemotherapy. Curative surgery in this stage is still an experimental approach. Only a small number of these metastatic patients show an oligometastatic disease with no uniform definition of what oligometastatic means in gastric cancer. Nevertheless, the question remains unanswered as to whether these patients are still candidates for curative concepts. Som
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20

Johnson, Shirley, Haylee Hartzog, Cecelia R. Valrie, et al. "Planning Mental Health and Social Support Prescreening Assessments for Adult Sickle Cell Disease Patients: Evaluating Readiness for Curative Therapy." Blood 144, Supplement 1 (2024): 7654. https://doi.org/10.1182/blood-2024-200954.

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Background: The foundation for the accreditation for cellular therapy (FACT) has published standards for hematopoietic cell therapy. The NIH Cure Sickle Cell Initiative (CureSCi) [i] has highlighted how the mental health and social readiness of sickle cell disease (SCD) candidates for curative therapy may be overlooked or undervalued. Virginia Commonwealth University Health (VCUHS) has therefore adapted CureSCi guidelines published in a white paper to develop a psychosocial readiness screening process intended to guide and support SCD patients and their potential curative therapy clinicians, a
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21

Gong, Lan, Xinghuai Sun, and William J. Chapin. "Clinical Curative Effect of Acupuncture Therapy on Xerophthalmia." American Journal of Chinese Medicine 38, no. 04 (2010): 651–59. http://dx.doi.org/10.1142/s0192415x10008123.

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This study observes changes in symptoms of xerophthalmia pre- and post-acupuncture therapy and compares the results of the acupuncture therapy (AT) group and the artificial tear control (ATC) group. Parallel comparative studies were carried out on 44 patients with xerophthalmia, who were divided into the AT group (n = 20) and the ATC group (n = 24). A 10-session acupuncture therapy program was performed for the AT group while Dextran 70 was used for the ATC group with each course of treatment lasting 21 day. Examinations were made on the day when a patient was chosen to join the study, 1 hour
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22

Gejalakshmi S and Harikrishnan N. "Yoga a Curative Therapy to Treat Multiple Sclerosis." International Journal of Research in Pharmaceutical Sciences 11, no. 4 (2020): 6834–36. http://dx.doi.org/10.26452/ijrps.v11i4.3653.

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Multiple sclerosis (MS) is characterised as an autoimmune disease originated from Central nervous system affecting the neurons Greymatter no evidence for treatment. Many recent approaches as alerted for treating for disease-modifying therapies for the treatment of multiple sclerosis no remedy has occurred for complete curative for MS. In this review, the author has pioneered the measures to control MS from its symptoms by using physical exercise yoga therapy. Yoga therapy has a beneficial role in controlling MS. The best practice of breathing exercise which we all of us do every day without th
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23

Scheinman, M. M. "Ventricular tachycardia. Chipping away at finding curative therapy." Circulation 78, no. 2 (1988): 481–82. http://dx.doi.org/10.1161/01.cir.78.2.481.

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24

Yukun, H., C. Luxiang, S. Zhiyuan, H. Guoxiang, and L. Jianping. "Curative effect of endovascular therapy on Takayasu arteritis." Heart 97, Suppl 3 (2011): A156. http://dx.doi.org/10.1136/heartjnl-2011-300867.456.

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25

Indelicato, D., J. Bradley, D. Klawinski, et al. "Curative Proton Therapy for Infants: At What Cost?" International Journal of Radiation Oncology*Biology*Physics 121, no. 3 (2025): e3. https://doi.org/10.1016/j.ijrobp.2024.11.017.

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26

Levin, Seymour H. "Cancer of the breast: Is radiation therapy curative." Biomedicine & Pharmacotherapy 52, no. 7-8 (1998): 328. http://dx.doi.org/10.1016/s0753-3322(98)80061-9.

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27

Hong, Yukun, and Luxiang Chi. "CURATIVE EFFECT OF ENDOVASCULAR THERAPY ON TAKAYASU ARTERITIS." Heart 98, Suppl 2 (2012): E284.2—E284. http://dx.doi.org/10.1136/heartjnl-2012-302920z.6.

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28

Ronson, Alain, and Jean-Jacques Body. "Psychosocial rehabilitation of cancer patients after curative therapy." Supportive Care in Cancer 10, no. 4 (2001): 281–91. http://dx.doi.org/10.1007/s005200100309.

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29

Feldman, Rebecca, and Edward S. Kim. "Prognostic and predictive biomarkers post curative intent therapy." Annals of Translational Medicine 5, no. 18 (2017): 374. http://dx.doi.org/10.21037/atm.2017.07.34.

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30

Jeng, Wen-Juei, Chen-Chun Lin, Wei-Ting Chen, I.-Shyan Sheen, Chun-Yen Lin, and Shi-Ming Lin. "Adjuvant Therapy for Hepatocellular Carcinoma after Curative Treatment." Digestive Diseases 32, no. 6 (2014): 747–54. http://dx.doi.org/10.1159/000368017.

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31

Kudo, Masatoshi. "Adjuvant Therapy after Curative Treatment for Hepatocellular Carcinoma." Oncology 81, s1 (2011): 50–55. http://dx.doi.org/10.1159/000333259.

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32

Tournoy, Kurt G., Valerie Adam, Inge Muylle, et al. "Health Outcomes with Curative and Palliative Therapies in Real World: Role of the Quality of Life Summary Score in Thoracic Oncology Patients." Cancers 15, no. 15 (2023): 3821. http://dx.doi.org/10.3390/cancers15153821.

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Background: For patients receiving therapy with curative or palliative intent for a thoracic malignancy, prediction of quality of life (QOL), once therapy starts, remains challenging. The role of health assessments by the patient instead of the doctor herein remains ill-defined. Aims: To assess the evolution of QOL in patients with thoracic malignancies treated with curative and palliative intent, respectively. To identify factors that determine QOL one year after the start of cancer therapy. To identify factors that affect survival. Methods: We prospectively included consecutive patients with
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33

Sathiyapalan, Arani, Ziad Baloush, and Peter M. Ellis. "Update on the Management of Stage III NSCLC: Navigating a Complex and Heterogeneous Stage of Disease." Current Oncology 30, no. 11 (2023): 9514–29. http://dx.doi.org/10.3390/curroncol30110689.

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Background: Stage III nonsmall cell lung cancer (NSCLC) represents a heterogeneous group of patients. Many patients are treated with curative intent multimodality therapy, either surgical resection plus systemic therapy or chemoradiation plus immunotherapy. However, many patients are not suitable for curative intent therapy and are treated with palliative systemic therapy or best supportive care. Methods: This paper is a review of recent advances in the management of patients with curative intent disease. Results: There have been significant advances in curative intent therapy for patients wit
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34

Butts, Emily, Denise Gococo-Benore, Tanmayi Pai, Ruqin Chen, Rami Manochakian, and Yanyan Lou. "Recurrence patterns following curative therapy for stage I NSCLC." Journal of Clinical Oncology 38, no. 15_suppl (2020): e21069-e21069. http://dx.doi.org/10.1200/jco.2020.38.15_suppl.e21069.

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e21069 Background: Lobectomy remains the standard of care for definitive management of stage I non-small cell lung cancer (NSCLC). Stereotactic body radiation therapy (SBRT) is considered primarily for patients who were either unwilling to have surgery or deemed to be medically unfit for surgery. Current NCCN guidelines indicate the use of CT for surveillance following curative-intent therapies and recommend CT every 6 months for 2-3 years followed by CT annually without clear guidance on how long to keep doing annual CT scans. This study aims to evaluate the patterns of lung cancer recurrence
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35

Hotta, Osamu. "Tonsillectomy combined with steroid pulse therapy: A curative therapy for IgA nephropathy." Acta Oto-Laryngologica 124 (December 1, 2004): 43–48. http://dx.doi.org/10.1080/03655230410003387.

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36

Lynch, Olivia Frances, Do Lee, Pamela Soulos, James B. Yu, Jeph Herrin, and Cary Philip Gross. "30 year trends in racial disparities for early stage lung cancer treatment." Journal of Clinical Oncology 43, no. 16_suppl (2025): 1599. https://doi.org/10.1200/jco.2025.43.16_suppl.1599.

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1599 Background: Racial disparities in lung cancer treatment have been recognized for over 30 years. Our prior work showed that among Medicare beneficiaries diagnosed during 1992-2002, Black patients were less likely to receive curative therapy than White patients. As treatment approaches have evolved and increased attention has been paid to healthcare disparities, it is unclear whether this pattern has changed over time. We assessed temporal trends in racial disparities in receipt of curative therapy from 2005 to 2019, and compared findings to estimates from over 25 years earlier. Methods: Us
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37

Nickel, Robert Sheppard, Jacqueline Y. Maher, Michael H. Hsieh, Meghan F. Davis, Matthew M. Hsieh, and Lydia H. Pecker. "Fertility after Curative Therapy for Sickle Cell Disease: A Comprehensive Review to Guide Care." Journal of Clinical Medicine 11, no. 9 (2022): 2318. http://dx.doi.org/10.3390/jcm11092318.

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Curative therapy for sickle cell disease (SCD) currently requires gonadotoxic conditioning that can impair future fertility. Fertility outcomes after curative therapy are likely affected by pre-transplant ovarian reserve or semen analysis parameters that may already be abnormal from SCD-related damage or hydroxyurea treatment. Outcomes are also likely affected by the conditioning regimen. Conditioning with myeloablative busulfan and cyclophosphamide causes serious gonadotoxicity particularly among post-pubertal females. Reduced-intensity and non-myeloablative conditioning may be acutely less g
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38

Fitzhugh, Courtney D., Emmanuel J. Volanakis, Ombeni Idassi, Josh A. Duberman, Michael R. DeBaun, and Debra L. Friedman. "Long-Term Health Effects of Curative Therapies on Heart, Lungs, and Kidneys for Individuals with Sickle Cell Disease Compared to Those with Hematologic Malignancies." Journal of Clinical Medicine 11, no. 11 (2022): 3118. http://dx.doi.org/10.3390/jcm11113118.

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The goal of curing children and adults with sickle cell disease (SCD) is to maximize benefits and minimize intermediate and long-term adverse outcomes so that individuals can live an average life span with a high quality of life. While greater than 2000 individuals with SCD have been treated with curative therapy, systematic studies have not been performed to evaluate the long-term health effects of hematopoietic stem cell transplant (HSCT) in this population. Individuals with SCD suffer progressive heart, lung, and kidney disease prior to curative therapy. In adults, these sequalae are associ
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39

Breitling, Lutz Philipp, Anja Rinke, and Thomas Mathias Gress. "Neuroendokrine Tumoren im Gastrointestinaltrakt." DMW - Deutsche Medizinische Wochenschrift 144, no. 21 (2019): 1509–21. http://dx.doi.org/10.1055/a-0865-0061.

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AbstractNeuroendocrine neoplasms (NEN) are increasingly diagnosed tumors with great clinical and prognostic heterogeneity. One of the peculiarities of NEN is the presence of a clinical hormone syndrome in about 30 % of cases. Somatostatin receptor imaging plays an important role in the diagnosis of spreading and in the planning of therapy. NEN patients should be co-supervised by specialized centers and if possible treated as part of studies. In the case of NEN with no or only circumscribed metastases, complete resection in curative intention is generally the highest therapeutic goal. Small neu
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40

Alibhai, Shabbir M. H., Gary Naglie, Robert Nam, John Trachtenberg, and Murray D. Krahn. "Do Older Men Benefit From Curative Therapy of Localized Prostate Cancer?" Journal of Clinical Oncology 21, no. 17 (2003): 3318–27. http://dx.doi.org/10.1200/jco.2003.09.034.

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Purpose: Prior decision-analytic models are based on outdated or suboptimal efficacy, patient preference, and comorbidity data. We estimated life expectancy (LE) and quality-adjusted life expectancy (QALE) associated with available treatments for localized prostate cancer in men aged ≥ 65 years, adjusting for Gleason score, patient preferences, and comorbidity. Methods: We evaluated three treatments, using a decision-analytic Markov model: radical prostatectomy (RP), external beam radiotherapy (EBRT), and watchful waiting (WW). Rates of treatment complications and pretreatment incontinence and
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41

Tallman, Martin S., and Jessica K. Altman. "Curative Strategies in Acute Promyelocytic Leukemia." Hematology 2008, no. 1 (2008): 391–99. http://dx.doi.org/10.1182/asheducation-2008.1.391.

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AbstractAcute promyelocytic leukemia (APL) was initially described as a distinct clinical entity in 1957, one year before the first meeting of the American Society of Hematology. With routine administration of all-trans retinoic acid (ATRA) combined with chemotherapy in the early 1990s and arsenic trioxide (ATO) in the late 1990s, cure can now be expected in the majority of both newly diagnosed and relapsed patients. ATRA with anthracycline-based chemotherapy for induction and consolidation followed by ATRA plus low-dose chemotherapy maintenance is currently the standard of care for newly diag
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42

Shamimi-Noori, Susan, Carin Gonsalves, and Colette Shaw. "Metastatic Liver Disease: Indications for Locoregional Therapy and Supporting Data." Seminars in Interventional Radiology 34, no. 02 (2017): 145–66. http://dx.doi.org/10.1055/s-0037-1602712.

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AbstractMetastatic liver disease is a major cause of cancer-related morbidity and mortality. Surgical resection is considered the only curative treatment, yet only a minority is eligible. Patients who present with unresectable disease are treated with systemic agents and/or locoregional therapies. The latter include thermal ablation and catheter-based transarterial interventions. Thermal ablation is reserved for those with limited tumor burden. It is used to downstage the disease to enable curative surgical resection, as an adjunct to surgery, or in select patients it is potentially curative.
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43

Outzen, Knud Erik, and Peter Illum. "CO2-laser therapy for carcinoma of the larynx." Journal of Laryngology & Otology 109, no. 2 (1995): 111–13. http://dx.doi.org/10.1017/s0022215100129421.

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AbstractA retrospective study was undertaken to assess the outcome of 19 consecutive patients, who underwent endolaryngeal resection with a CO2-laser for laryngeal carcinomas. Sixteen of these patients had recurrences after primary curative radiotherapy. Seventeen of the patients had a curative operation carried out. So far, four CO2-laser treatment failures have been observed (median observation time 35 months). None of the patients needed tracheostomy in connection with the operation. Voice quality was in all cases acceptable.It is recommended, that small recurrences (after radiotherapy of l
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44

Jiang, Di Maria, Chihiro Suzuki, Osvaldo Espin-Garcia, et al. "Surveillance and outcomes after curative resection for gastroesophageal adenocarcinoma (GEAC)." Journal of Clinical Oncology 37, no. 4_suppl (2019): 162. http://dx.doi.org/10.1200/jco.2019.37.4_suppl.162.

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162 Background: Although commonly performed, the benefit of routine surveillance testing (SvT) following curative resection of GEAC is undefined. We aimed to determine frequency of successful salvage therapy (SST) in patients (pts) with relapsed GEAC who were surveyed post curative therapy. Methods: Between 2011 and 2016, 210 consecutive pts with locally advanced GEAC underwent curative surgery and subsequent surveillance at Princess Margaret Cancer Center. SST was defined as any potentially curative therapy for recurrence which resulted in post-recurrence survival (PRS) two years without furt
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45

Chung, Matthew Shing Hin, Rex Wan-Hin Hui, Lu Li, et al. "Factors associated with immunotherapy response for hepatocellular carcinoma." Journal of Clinical Oncology 43, no. 16_suppl (2025): 4106. https://doi.org/10.1200/jco.2025.43.16_suppl.4106.

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4106 Background: Immunotherapy has shown remarkable progress in treating hepatocellular carcinoma (HCC) in recent years. We aim to investigate the clinical factors associated with treatment response to HCC immunotherapy in Asian population. Methods: We identifiedHCC patients receiving immunotherapy (nivolumab, pembrolizumab, atezolizumab, durvalumab, tremelimumab, ipilimumab; including monotherapies or combinations) from January 2008 to June 2024 from a population-based cohort in Hong Kong. Primary outcomes were all-cause mortality and hospitalization stratified by etiology of HCC [Viral-HCC,
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46

Frankul, Leana, and Catherine Frenette. "Hepatocellular Carcinoma: Downstaging to Liver Transplantation as Curative Therapy." Journal of Clinical and Translational Hepatology 000, no. 000 (2021): 000. http://dx.doi.org/10.14218/jcth.2020.00037.

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47

Cravo, Marília. "Towards curative therapy in gastric cancer: Faraway, so close!" World Journal of Gastroenterology 21, no. 41 (2015): 11609. http://dx.doi.org/10.3748/wjg.v21.i41.11609.

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48

Williams, David A., and Erica Esrick. "Investigational curative gene therapy approaches to sickle cell disease." Blood Advances 5, no. 23 (2021): 5452. http://dx.doi.org/10.1182/bloodadvances.2021005567.

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Abstract Sickle cell disease (SCD) is an inherited blood condition resulting from abnormal hemoglobin production. It is one of the most common genetic diseases in the world. The clinical manifestations are variable and range from recurrent acute and debilitating painful crises to life-threatening pulmonary, cardiovascular, renal, and neurologic complications. The only curative treatment of SCD at this time is bone marrow transplantation (also called hematopoietic stem cell transplantation) using healthy blood stem cells from an unaffected brother or sister or from an unrelated donor if one can
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49

Biffi, Alessandra. "Gene Therapy as a Curative Option for β-Thalassemia". New England Journal of Medicine 378, № 16 (2018): 1551–52. http://dx.doi.org/10.1056/nejme1802169.

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50

Pavlovic-Markovic, Aleksandra, Sanja Dragasevic, Miodrag Krstic, Milica Stojkovic Lalosevic, and Tomica Milosavljevic. "Assessment of Duodenal Adenomas and Strategies for Curative Therapy." Digestive Diseases 37, no. 5 (2019): 374–80. http://dx.doi.org/10.1159/000496697.

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Background: The increasing incidence of duodenal neoplasm has underlined different methods of resection depending on the clinical presentation, endoscopic features and histopathology. In this comprehensive review, we systematically describe the current knowledge concerning the diagnosis and management of duodenal adenomas (DAs) and discuss data considering all possible therapeutic approaches. Summary: Among a variety of duodenal lesions, including neuroendocrine tumors and gastrointestinal stromal tumors, DAs present precancerous lesions of the duodenal papilla or non-ampullary region necessit
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