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Journal articles on the topic 'Curcuma comosa'

Author: Grafiati

Published: 4 June 2021

Last updated: 9 February 2022

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1

Kaewamatawong, Rawiwun, Preecha Boonchoong, and Nongnit Teerawatanasuk. "Diarylheptanoids from Curcuma comosa." Phytochemistry Letters 2, no. 1 (February 2009): 19–21. http://dx.doi.org/10.1016/j.phytol.2008.10.004.

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2

Qu, Yang, Fengming Xu, Seikou Nakamura, Hisashi Matsuda, Yutana Pongpiriyadacha, Lijun Wu, and Masayuki Yoshikawa. "Sesquiterpenes from Curcuma comosa." Journal of Natural Medicines 63, no. 1 (July 29, 2008): 102–4. http://dx.doi.org/10.1007/s11418-008-0282-8.

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3

Pintatum, Aknarin, Wisanu Maneerat, Emilie Logie, Emmy Tuenter, Maria E. Sakavitsi, Luc Pieters, Wim Vanden Berghe, Tawanun Sripisut, Suwanna Deachathai, and Surat Laphookhieo. "In Vitro Anti-Inflammatory, Anti-Oxidant, and Cytotoxic Activities of Four Curcuma Species and the Isolation of Compounds from Curcuma aromatica Rhizome." Biomolecules 10, no. 5 (May 21, 2020): 799. http://dx.doi.org/10.3390/biom10050799.

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The genus Curcuma is part of the Zingiberaceae family, and many Curcuma species have been used as traditional medicine and cosmetics in Thailand. To find new cosmeceutical ingredients, the in vitro anti-inflammatory, anti-oxidant, and cytotoxic activities of four Curcuma species as well as the isolation of compounds from the most active crude extract (C. aromatica) were investigated. The crude extract of C. aromatica showed 2,2-diphenyl-1-picrylhydrazyl (DPPH) radical scavenging activity with an IC50 value of 102.3 μg/mL. The cytotoxicity effect of C. aeruginosa, C. comosa, C. aromatica, and C. longa extracts assessed with the 3-[4,5-dimethylthiazol-2-yl]-2,5-diphenyl tetrazolium bromide (MTT) assay at 200 μg/mL were 12.1 ± 2.9, 14.4 ± 4.1, 28.6 ± 4.1, and 46.9 ± 8.6, respectively. C. aeruginosa and C. comosa presented apoptosis cells (57.7 ± 3.1% and 32.6 ± 2.2%, respectively) using the CytoTox-ONE™ assay. Different crude extracts or phytochemicals purified from C. aromatica were evaluated for their anti-inflammatory properties. The crude extract of C. aromatica showed the highest potential to inhibit NF-κB activity, followed by C. aeruginosa, C. comosa, and C. longa, respectively. Among the various purified phytochemicals curcumin, germacrone, curdione, zederone, and curcumenol significantly inhibited NF-κB activation in tumor necrosis factor (TNF) stimulated HaCaT keratinocytes. Of all compounds, curcumin was the most potent anti-inflammatory.

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4

Jurgens, Tannis M., Easter G. Frazier, James M. Schaeffer, Tracey E. Jones, Deborah L. Zink, Robert P. Borris, Weerachai Nanakorn, Hans T. Beck, and Michael J. Balick. "Novel Nematocidal Agents from Curcuma comosa." Journal of Natural Products 57, no. 2 (February 1994): 230–35. http://dx.doi.org/10.1021/np50104a006.

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5

Piyachaturawat, P., S. Ercharuporn, and A. Suksamrarn. "Uterotrophic Effect of Curcuma comosa in Rats." International Journal of Pharmacognosy 33, no. 4 (January 1995): 334–38. http://dx.doi.org/10.3109/13880209509065388.

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6

Xu, Fengming, Seikou Nakamura, Yang Qu, Hisashi Matsuda, Yutana Pongpiriyadacha, Lijun Wu, and Masayuki Yoshikawa. "Structures of New Sesquiterpenes from Curcuma comosa." CHEMICAL & PHARMACEUTICAL BULLETIN 56, no. 12 (2008): 1710–16. http://dx.doi.org/10.1248/cpb.56.1710.

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7

Burapan, Supawadee, Mihyang Kim, Yingyong Paisooksantivatana, Bekir Engin Eser, and Jaehong Han. "Thai Curcuma Species: Antioxidant and Bioactive Compounds." Foods 9, no. 9 (September 2, 2020): 1219. http://dx.doi.org/10.3390/foods9091219.

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For the functional food applications, antioxidant properties and the bioactive compounds of the 23 Curcuma species commercially cultivated in Thailand were studied. Total phenolic content and DPPH radical scavenging activity were determined. The concentrations of eight bioactive compounds, including curcumin (1), demethoxycurcumin (2), bisdemethoxycurcumin (3), 1,7-diphenyl-(4E,6E)-4,6-heptadien-3-ol (4), germacrone (5), furanodienone (6), zederone (7), and ar-turmerone (8), were determined from the Curcuma by HPLC. While the total phenolic content of C. longa was highest (22.3 ± 2.4 mg GAE/g, mg of gallic acid equivalents), C. Wan Na-Natong exhibited the highest DPPH (2,2-diphenyl-1-picryl-hydrazyl-hydrate) radical scavenging activity. Twenty-three Curcuma species showed characteristic distributions of the bioactive compounds, which can be utilized for the identification and authentication of the cultivated Curcuma species. C. longa contained the highest content of curcumin (1) (304.9 ± 0.1 mg/g) and C. angustifolia contained the highest content of germacrone (5) (373.9 ± 1.1 mg/g). It was noteworthy that 1,7-diphenyl-(4E,6E)-4,6-heptadien-3-ol (4) was found only from C. comosa at a very high concentration (300.7 ± 1.4 mg/g). It was concluded that Thai Curcuma species have a great potential for the application of functional foods and ingredients.

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8

Boonmee, Apaporn, Chantragan Srisomsap, Daranee Chokchaichamnankit, Aphichart Karnchanatat, and Polkit Sangvanich. "A proteomic analysis of Curcuma comosa Roxb. rhizomes." Proteome Science 9, no. 1 (2011): 43. http://dx.doi.org/10.1186/1477-5956-9-43.

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9

Boonmee, Apaporn, Chantragan Srisomsap, Aphichart Karnchanatat, and Polkit Sangvanich. "An antioxidant protein in Curcuma comosa Roxb. Rhizomes." Food Chemistry 124, no. 2 (January 2011): 476–80. http://dx.doi.org/10.1016/j.foodchem.2010.06.057.

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10

Chokchaisiri, Ratchanaporn, Phongsak Innok, and Apichart Suksamrarn. "Flavonoid glycosides from the aerial parts of Curcuma comosa." Phytochemistry Letters 5, no. 2 (June 2012): 361–66. http://dx.doi.org/10.1016/j.phytol.2012.03.003.

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11

Suksamrarn, Apichart, Salinee Eiamong, Pawinee Piyachaturawat, and Lindsay T. Byrne. "A phloracetophenone glucoside with choleretic activity from Curcuma comosa." Phytochemistry 45, no. 1 (May 1997): 103–5. http://dx.doi.org/10.1016/s0031-9422(96)00778-9.

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12

Piyachaturawat, P., R. Gansar, and A. Suksamrarn. "Choleretic Effect of Curcuma comosa Rhizome Extracts in Rats." International Journal of Pharmacognosy 34, no. 3 (January 1996): 174–78. http://dx.doi.org/10.1076/phbi.34.3.174.13204.

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13

Joob, Beuy, and Viroj Wiwanitkit. "Acute breast pain after intake of Curcuma comosa Roxb rhizome." Journal of Acute Disease 3, no. 3 (2014): 211. http://dx.doi.org/10.1016/s2221-6189(14)60046-9.

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14

Piyachaturawat, P., A. Timinkul, A. Chuncharunee, and A. Suksamrarn. "Effect of Curcuma comosa Extract on Male Fertility in Rats." Pharmaceutical Biology 37, no. 1 (January 1999): 22–27. http://dx.doi.org/10.1076/phbi.37.1.22.6311.

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15

Nakamura, Seikou, Yang Qu, Fengming Xu, Hisashi Matsuda, and Masayuki Yoshikawa. "Structures of New Monoterpenes from Thai Herbal Medicine Curcuma comosa." CHEMICAL & PHARMACEUTICAL BULLETIN 56, no. 11 (2008): 1604–6. http://dx.doi.org/10.1248/cpb.56.1604.

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16

Vinayavekhin, Nawaporn, Jetjamnong Sueajai, Nichaboon Chaihad, Ratchanee Panrak, Ratchanaporn Chokchaisiri, Polkit Sangvanich, Apichart Suksamrarn, and Pawinee Piyachaturawat. "Serum lipidomics analysis of ovariectomized rats under Curcuma comosa treatment." Journal of Ethnopharmacology 192 (November 2016): 273–82. http://dx.doi.org/10.1016/j.jep.2016.07.054.

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17

Viriyaadhammaa, Natsima, Aroonchai Saiai, Waranya Neimkhum, Wariya Nirachonkul, Wantida Chaiyana, Sawitree Chiampanichayakul, Singkome Tima, Toyonobu Usuki, Suwit Duangmano, and Songyot Anuchapreeda. "Cytotoxic and Antiproliferative Effects of Diarylheptanoids Isolated from Curcuma comosa Rhizomes on Leukaemic Cells." Molecules 25, no. 22 (November 23, 2020): 5476. http://dx.doi.org/10.3390/molecules25225476.

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Curcuma comosa belongs to the Zingiberaceae family. In this study, two natural compounds were isolated from C. comosa, and their structures were determined using nuclear magnetic resonance. The isolated compounds were identified as 7-(3,4-dihydroxyphenyl)-5-hydroxy-1-phenyl-(1E)-1-heptene (1) and trans-1,7-diphenyl-5-hydroxy-1-heptene (2). Compound 1 showed the strongest cytotoxicity effect against HL-60 cells, while its antioxidant and anti-inflammatory properties were stronger than those of compound 2. Compound 1 proved to be a potent antioxidant, compared to ascorbic acid. Neither compounds had any effect on red blood cell haemolysis. Furthermore, compound 1 significantly decreased Wilms’ tumour 1 protein expression and cell proliferation in KG-1a cells. Compound 1 decreased the WT1 protein levels in a time- and dose- dependent manner. Compound 1 suppressed cell cycle at the S phase. In conclusion, compound 1 has a promising chemotherapeutic potential against leukaemia.

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18

Piyachaturawat, Pawinee, Jinda Charoenpiboonsin, Chaivat Toskulkao, and Apichart Suksamrarn. "Reduction of plasma cholesterol by Curcuma comosa extract in hypercholesterolaemic hamsters." Journal of Ethnopharmacology 66, no. 2 (August 1999): 199–204. http://dx.doi.org/10.1016/s0378-8741(98)00170-6.

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19

Winuthayanon, Wipawee, Kanoknetr Suksen, Chuenchit Boonchird, Aporn Chuncharunee, Mathurose Ponglikitmongkol, Apichart Suksamrarn, and Pawinee Piyachaturawat. "Estrogenic Activity of Diarylheptanoids from Curcuma comosa Roxb. Requires Metabolic Activation." Journal of Agricultural and Food Chemistry 57, no. 3 (February 11, 2009): 840–45. http://dx.doi.org/10.1021/jf802702c.

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20

Alan, Chuncharunee, Habuddha Valainipa, and Chuncharunee Aporn. "Curcuma comosa ameliorates cisplatin-induced nephrotoxicity: COX-2 expression and ultrastructure changes." Journal of Medicinal Plants Research 10, no. 34 (September 10, 2016): 595–602. http://dx.doi.org/10.5897/jmpr2016.6151.

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21

Su, Jian, Kittisak Sripanidkulchai, Apichart Suksamrarn, Ying Hu, Pawinee Piyachuturawat, and Bungorn Sripanidkulchai. "Pharmacokinetics and organ distribution of diarylheptanoid phytoestrogens from Curcuma comosa in rats." Journal of Natural Medicines 66, no. 3 (November 20, 2011): 468–75. http://dx.doi.org/10.1007/s11418-011-0607-x.

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22

Matsumoto, Takahiro, Seikou Nakamura, Katsuyoshi Fujimoto, Tomoe Ohta, Keiko Ogawa, Masayuki Yoshikawa, Eri Onishi, Masashi Fukaya, and Hisashi Matsuda. "Structure of diarylheptanoids with antiallergic activity from the rhizomes of Curcuma comosa." Journal of Natural Medicines 69, no. 1 (October 10, 2014): 142–47. http://dx.doi.org/10.1007/s11418-014-0870-8.

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23

Sutjarit, Nareerat, Jetjamnong Sueajai, Nittaya Boonmuen, Nilubon Sornkaew, Apichart Suksamrarn, Patoomratana Tuchinda, Weiming Zhu, Jittima Weerachayaphorn, and Pawinee Piyachaturawat. "Curcuma comosa reduces visceral adipose tissue and improves dyslipidemia in ovariectomized rats." Journal of Ethnopharmacology 215 (April 2018): 167–75. http://dx.doi.org/10.1016/j.jep.2017.12.027.

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24

Jariyawat, Surawat, Thanapol Thammapratip, Kanoknetr Suksen, Podchanart Wanitchakool, Jintapat Nateewattana, Arthit Chairoungdua, Apichart Suksamrarn, and Pawinee Piyachaturawat. "Induction of apoptosis in murine leukemia by diarylheptanoids from Curcuma comosa Roxb." Cell Biology and Toxicology 27, no. 6 (July 16, 2011): 413–23. http://dx.doi.org/10.1007/s10565-011-9196-4.

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25

Ishibashi, Masami, Rolly G. Fuentes, Kazufumi Toume, Midori A. Arai, Takashi Koyano, and Thaworn Kowithayakorn. "Constituents from the Rhizomes of Curcuma comosa and Their Wnt Signal Inhibitory Activities." HETEROCYCLES 88, no. 2 (2014): 1501. http://dx.doi.org/10.3987/com-13-s(s)49.

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26

Chiu, Chi-Ming, Jukkrit Nootem, Thanapich Santiwat, Choladda Srisuwannaket, Kornkanya Pratumyot, Wei-Chao Lin, Withawat Mingvanish, and Nakorn Niamnont. "Enhanced Stability and Bioactivity of Curcuma comosa Roxb. Extract in Electrospun Gelatin Nanofibers." Fibers 7, no. 9 (August 27, 2019): 76. http://dx.doi.org/10.3390/fib7090076.

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Electrospun fiber can be used as a carrier for releasing active ingredients at the target site to achieve the effects of drug treatment. The objectives of this research work were to study suitable conditions for producing electrospun gelatin fiber loaded with crude Curcuma comosa Roxb. extract (CE) and to study antioxidant, anti-tyrosinase and anti-bacterial activities and its freeze–thaw stability as well. To achieve optimal conditions for producing electrospun gelatin fiber, the concentration of gelatin was adjusted to 30% w/v in a co-solvent system of acetic acid/water (9:1 v/v) with a feed rate of 3 mL/h and an applied voltage of 15 kV. The lowest percent loading of 5% (w/v) CE in gelatin nanofiber exhibited the highest DPPH radical scavenging activity of 94% and the highest inhibition of tyrosinase enzyme of 35%. Moreover, the inhibition zones for antibacterial activities against S. aureus and S. epidermidis were 7.77 ± 0.21 and 7.73 ± 0.12 mm, respectively. The freeze–thaw stability of CE in electrospun gelatin nanofiber was significantly different (p < 0.05) after the 4th cycle as compared to CE. Electrospun gelatin nanofiber containing CE also showed the capacity of the release of bioactive ingredients possessing anti-oxidant properties and, therefore, it could potentially be used for face masks.

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27

Su, Jian, Kittisak Sripanidkulchai, Ying Hu, Rungsiri Chaiittianan, and Bungorn Sripanidkulchai. "Increased In Situ Intestinal Absorption of Phytoestrogenic Diarylheptanoids from Curcuma comosa in Nanoemulsions." AAPS PharmSciTech 14, no. 3 (June 26, 2013): 1055–62. http://dx.doi.org/10.1208/s12249-013-9996-3.

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28

Intapad, Suttira, Apichart Suksamrarn, and Pawinee Piyachaturawat. "Enhancement of vascular relaxation in rat aorta by phytoestrogens from Curcuma comosa Roxb." Vascular Pharmacology 51, no. 4 (October 2009): 284–90. http://dx.doi.org/10.1016/j.vph.2009.07.005.

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29

Tuntiyasawasdikul, Sarunya, Ekapol Limpongsa, Napaphak Jaipakdee, and Bungorn Sripanidkulchai. "Development and evaluation of topical films containing phytoestrogenic diaryheptanoids from Curcuma comosa extract." Drug Development and Industrial Pharmacy 44, no. 8 (March 26, 2018): 1385–94. http://dx.doi.org/10.1080/03639045.2018.1453518.

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30

Jariyawat, Surawat, Pranida Kigpituck, Kanoknetr Suksen, Aporn Chuncharunee, Arusa Chaovanalikit, and Pawinee Piyachaturawat. "Protection against cisplatin-induced nephrotoxicity in mice by Curcuma comosa Roxb. ethanol extract." Journal of Natural Medicines 63, no. 4 (June 18, 2009): 430–36. http://dx.doi.org/10.1007/s11418-009-0345-5.

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31

Tabboon, Peera, Sarunya Tuntiyasawasdikul, and Bungorn Sripanidkulchai. "Quality and stability assessment of commercial products containing phytoestrogen diaryheptanoids from Curcuma comosa." Industrial Crops and Products 134 (August 2019): 216–24. http://dx.doi.org/10.1016/j.indcrop.2019.03.062.

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32

Chuaicharoen, Pavadee, Tumnoon Charaslertrangsi, Aporn Chuncharunee, Apichart Suksamrarn, and Pawinee Piyachaturawat. "Non-Phenolic Diarylheptanoid from Curcuma comosa Protects Against Thioacetamide-Induced Acute Hepatotoxicity in Mice." Pharmaceutical Sciences Asia 47, no. 1 (2020): 74–85. http://dx.doi.org/10.29090/psa.2020.01.019.0004.

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33

Weerachayaphorn, Jittima, Aporn Chuncharunee, Chitrawina Mahagita, Buarong Lewchalermwongse, Apichart Suksamrarn, and Pawinee Piyachaturawat. "A protective effect of Curcuma comosa Roxb. on bone loss in estrogen deficient mice." Journal of Ethnopharmacology 137, no. 2 (September 2011): 956–62. http://dx.doi.org/10.1016/j.jep.2011.06.040.

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34

Piyachaturawat, P., A. Timinkul, A. Chuncharunee, and A. Suksamrarn. "Growth Suppressing Effect of Curcuma Comosa Extract on Male Reproductive Organs in Immature Rats." Pharmaceutical Biology 36, no. 1 (January 1998): 44–49. http://dx.doi.org/10.1076/phbi.36.1.44.4618.

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35

Jaipakdee, Napaphak, Ekapol Limpongsa, Bung-orn Sripanidkulchai, and Pawinee Piyachaturawat. "Preparation of Curcuma comosa tablets using liquisolid techniques: In vitro and in vivo evaluation." International Journal of Pharmaceutics 553, no. 1-2 (December 2018): 157–68. http://dx.doi.org/10.1016/j.ijpharm.2018.10.031.

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36

Tunpanich, Pamika, Ekapol Limpongsa, Thaned Pongjanyakul, Bungorn Sripanidkulchai, and Napaphak Jaipakdee. "Mucoadhesive sustained-release tablets for vaginal delivery of Curcuma comosa extracts: Preparation and characterization." Journal of Drug Delivery Science and Technology 51 (June 2019): 559–68. http://dx.doi.org/10.1016/j.jddst.2019.03.030.

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37

Tuntiyasawasdikul, Sarunya, Ekapol Limpongsa, Napaphak Jaipakdee, and Bungorn Sripanidkulchai. "Effects of Vehicles and Enhancers on the Skin Permeation of Phytoestrogenic Diarylheptanoids from Curcuma comosa." AAPS PharmSciTech 18, no. 3 (July 5, 2016): 895–903. http://dx.doi.org/10.1208/s12249-016-0582-3.

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38

Jantaratnotai, Nattinee, Pongsak Utaisincharoen, Pawinee Piyachaturawat, Sukumal Chongthammakun, and Yupin Sanvarinda. "Inhibitory effect of Curcuma comosa on NO production and cytokine expression in LPS-activated microglia." Life Sciences 78, no. 6 (January 2006): 571–77. http://dx.doi.org/10.1016/j.lfs.2005.04.065.

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39

Vattanarongkup, Jaturavit, Pawinee Piyachaturawat, Patoomratana Tuchinda, Pimtip Sanvarinda, Yupin Sanvarinda, and Nattinee Jantaratnotai. "Protective Effects of a Diarylheptanoid from Curcuma comosa Against Hydrogen Peroxide-Induced Astroglial Cell Death." Planta Medica 82, no. 17 (June 24, 2016): 1456–62. http://dx.doi.org/10.1055/s-0042-109173.

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40

Intapad, Suttira, Vitoon Saengsirisuwan, Mujalin Prasannarong, Aporn Chuncharunee, Wisuda Suvitayawat, Ratchanaporn Chokchaisiri, Apichart Suksamrarn, and Pawinee Piyachaturawat. "Long-Term Effect of Phytoestrogens from Curcuma comosa Roxb. on Vascular Relaxation in Ovariectomized Rats." Journal of Agricultural and Food Chemistry 60, no. 3 (January 12, 2012): 758–64. http://dx.doi.org/10.1021/jf203173b.

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41

Tantikanlayaporn, Duangrat, Patsorn Wichit, Jittima Weerachayaphorn, Arthit Chairoungdua, Aporn Chuncharunee, Apichart Suksamrarn, and Pawinee Piyachaturawat. "Bone Sparing Effect of a Novel Phytoestrogen Diarylheptanoid from Curcuma comosa Roxb. in Ovariectomized Rats." PLoS ONE 8, no. 11 (November 11, 2013): e78739. http://dx.doi.org/10.1371/journal.pone.0078739.

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42

Keeratinijakal, Vichien, and Sumet Kongkiatpaiboon. "Distribution of phytoestrogenic diarylheptanoids and sesquiterpenoids components in Curcuma comosa rhizomes and its related species." Revista Brasileira de Farmacognosia 27, no. 3 (May 2017): 290–96. http://dx.doi.org/10.1016/j.bjp.2016.12.003.

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43

Weerachayaphorn, Jittima, Aporn Chuncharunee, Surawat Jariyawat, Buarong Lewchalermwong, Sirirat Amonpatumrat, Apichart Suksamrarn, and Pawinee Piyachaturawat. "Protection of centrilobular necrosis by Curcuma comosa Roxb. in carbon tetrachloride-induced mice liver injury." Journal of Ethnopharmacology 129, no. 2 (May 2010): 254–60. http://dx.doi.org/10.1016/j.jep.2010.03.026.

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44

Vichien, Keeratinijakal, Kladmook Maytinee, and Laosatit Kularb. "Identification and characterization of Curcuma comosa Roxb., phytoestrogens-producing plant, using AFLP markers and morphological characteristics." Journal of Medicinal Plants Research 4, no. 24 (December 18, 2010): 2651–57. http://dx.doi.org/10.5897/jmpr09.381.

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45

Sornkaew, Nilubon, Yuan Lin, Fei Wang, Guolin Zhang, Ratchanaporn Chokchaisiri, Ailian Zhang, Kanjana Wongkrajang, Parichat Suebsakwong, Pawinee Piyachaturawat, and Apichart Suksamrarn. "Diarylheptanoids of Curcuma comosa with Inhibitory Effects on Nitric Oxide Production in Macrophage RAW 264.7 Cells." Natural Product Communications 10, no. 1 (January 2015): 1934578X1501000. http://dx.doi.org/10.1177/1934578x1501000123.

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Eight new diarylheptanoids, a 1.2:1 mixture of (3S)- and (3 R)-1-(4-hydroxyphenyl)-7-phenyl-(4 E,6 E)-4,6-heptadien-3-ol (1a and 1b), a racemic mixture of (3S)- and (3 R)-1-(4-hydroxyphenyl)-3-methoxy-7-phenyl-(4 E,6 E)-4,6-heptadiene (2a and 2b), a ca. 1:1 mixture of (3S)- and (3 R)-1-(4-hydroxy-3-methoxyphenyl)-3-methoxy-7-phenyl)-(4 E,6 E)-4,6-heptadiene (3a and 3b), 3-acetoxy-1-(3,4-dihydroxyphenyl)-7-phenylheptan-5-ol (4), (3 R)-1-(4,5-dihydroxyphenyl)-7-phenyl-(6 E)-6-hepten-3,2′-epoxide (5), and thirteen known diarylheptanoids, 6-12, a 3:1 mixture of 13a and 13b, and 14-17, were isolated from the rhizomes of Curcuma comosa from Sakon Nakhon, northeastern part of Thailand. The isolated compounds were evaluated for their antiinflammatory activities on the inhibition of lipopolysaccharide-induced nitric oxide production in macrophage RAW 264.7 cells and the diarylheptanoids 1a and 1b mixture and 14 exhibited potent inhibitory activity.

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46

Matsumoto, Takahiro, Seikou Nakamura, Souichi Nakashima, Masayuki Yoshikawa, Katsuyoshi Fujimoto, Tomoe Ohta, Azumi Morita, Rie Yasui, Eri Kashiwazaki, and Hisashi Matsuda. "Diarylheptanoids with inhibitory effects on melanogenesis from the rhizomes of Curcuma comosa in B16 melanoma cells." Bioorganic & Medicinal Chemistry Letters 23, no. 18 (September 2013): 5178–81. http://dx.doi.org/10.1016/j.bmcl.2013.07.010.

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Suksamrarn, Apichart, Mathurose Ponglikitmongkol, Kanjana Wongkrajang, Anon Chindaduang, Suthadta Kittidanairak, Aroon Jankam, Boon-ek Yingyongnarongkul, et al. "Diarylheptanoids, new phytoestrogens from the rhizomes of Curcuma comosa: Isolation, chemical modification and estrogenic activity evaluation." Bioorganic & Medicinal Chemistry 16, no. 14 (July 2008): 6891–902. http://dx.doi.org/10.1016/j.bmc.2008.05.051.

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Su, Jian, Kittisak Sripanidku, Ying Hu, and Bungorn Sripanidku. "Curcuma comosa Prevents the Neuron Loss and Affects the Antioxidative Enzymes in Hippocampus of Ethanol-treated Rats." Pakistan Journal of Biological Sciences 15, no. 8 (April 1, 2012): 367–73. http://dx.doi.org/10.3923/pjbs.2012.367.373.

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Lo-apirukkul, Sureerat, Thaya Jenjittikul, Promchit Saralamp, and Sompop Prathanturarug. "Micropropagation of a Thai medicinal plant for women’s health, Curcuma comosa Roxb., via shoot and microrhizome inductions." Journal of Natural Medicines 66, no. 2 (August 18, 2011): 265–70. http://dx.doi.org/10.1007/s11418-011-0577-z.

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Tantikanlayaporn, Duangrat, Lisa J. Robinson, Apichart Suksamrarn, Pawinee Piyachaturawat, and Harry C. Blair. "A diarylheptanoid phytoestrogen from Curcuma comosa, 1,7-diphenyl-4,6-heptadien-3-ol, accelerates human osteoblast proliferation and differentiation." Phytomedicine 20, no. 8-9 (June 2013): 676–82. http://dx.doi.org/10.1016/j.phymed.2013.02.008.

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