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Journal articles on the topic 'Curcuma Longa 0.5% extract'

Author: Grafiati

Published: 5 June 2025

Last updated: 16 July 2025

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1

Ezeuko, V. C., and E. I. Omorogbe. "Hepatoprotective activity of aqueous <i>Curcuma longa</i> rhizome extract against carbon tetrachloride-induced liver toxicity in adult Wistar rats." Dutse Journal of Pure and Applied Sciences 10, no. 2c (2024): 45–54. http://dx.doi.org/10.4314/dujopas.v10i2c.5.

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The aim of the study was to assess the protective potentials of aqueous extract of Curcuma longa rhizome on carbon tetrachloride-induced liver toxicity in adult Wistar rats. 30 male adult Wistar rats weighing between 180 and 250 g were used in the study and were randomly assigned into 6 groups containing 5 rats each. The study lasted for eight weeks; Group 1 served as control and received no administration. Group 2 received 1 ml/kg body weight of carbon tetrachloride; group 3 received 200 mg/kg body weight of Curcuma longa extract; group 4 received 400 mg/kg body weight of Curcuma longa extrac

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Firman, Gelline Tama Anindia, Min Rahminiwati, and Ike Yulia Wiendarlina. "AKTIVITAS HEPATOPROTEKTOR KOMBINASI EKSTRAK AIR PEGAGAN (Centella asiatica L. Urban) DAN EKSTRAK ETANOL KUNYIT (Curcuma longa Linn) TERHADAP TIKUS PUTIH JANTAN SPRAGUE DAWLEY." FITOFARMAKA: Jurnal Ilmiah Farmasi 7, no. 1 (2017): 13–28. http://dx.doi.org/10.33751/jf.v7i1.797.

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ABSTRAKHepatoproktektor adalah senyawa yang dapat mencegah dan memperbaiki sel-sel hepar yang rusak. Parameter yang diamati adalah perubahan kadar SGPT pada hari ke 0,2, 5, 9 dan 13. Hasil penelitian dari 9 kombinasi dosis selama 13 hari menunjukkan semua kombinasi menurunkan kadar SGPT dengan aktivitas hepatoprotektor terbaik adalah terdapat pada tumbuhan ektrak air pegagan: ekstrak etanol kunyit dengan perbandingan 2:3.Kata kunci: Pegagan (Centella asiatica L.Urban), Kunyit (Curcuma longa Linn) dan hepatoprotektorABSTRACTHepatoprotector is a compound that can prevent and repair liver cell da

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Medelyn, A. Aglipay. "Response of turmeric (Curcuma longa) extract on the growth performance and sensory evaluation of broilers." International Journal of Biosciences (IJB) 24, no. 1 (2024): 125–31. https://doi.org/10.5281/zenodo.11081828.

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The widespread concern about the consumption of healthy foods from animal and plant sources directed research efforts on the utilization of herbal plants for animal feeding. The study aimed to determine the growth performance of broilers supplemented with turmeric extract at different levels as a supplement to drinking water. Two-hundred forty-head day-old chicks were distributed in five treatments replicated six times following the Randomized Complete Block Design. The different treatments were: T<sub>0</sub> – 2.5 ml of electrolytes per liter of water (Control); T<sub>1</sub>&nbsp

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Riani, Ni Wayan Anantika, I. Made Susila Utama, and Ida Bagus Oka Winaya. "The Hepatoprotective Effect of Curcuma longa Extract on Dengue Virus Serotype-2 infected BALB/c Mice." Open Access Macedonian Journal of Medical Sciences 11, A (2023): 111–16. http://dx.doi.org/10.3889/oamjms.2023.8993.

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BACKGROUND: Dengue infection has a wide clinical spectrum ranging from asymptomatic infection to severe form with organ damage. Liver is among the common organ affected. Curcuma longa is a widely used herb that exhibits a hepatoprotective effect. AIM: This study aimed to investigate effect of C. longa on liver necroinflammatory activity and alanine aminotransferase (ALT) levels in dengue virus serotype-2 (DENV-2) infected BALB/c mice. MATERIALS AND METHODS: BALB/c mice were assigned into Group 1 (healthy mice), Group 2 (without C. longa administration), and Group 3 (C. longa administered). DEN

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Sitepu, Sukma Aditya, Julia Marisa, and Muhammad Miftah Farid. "The Effect of Extract Turmeric (Curcuma longa) on Spermatozoa Motility in Fresh Semen of Goats." Asian Journal of Biology 18, no. 2 (2023): 15–19. http://dx.doi.org/10.9734/ajob/2023/v18i2339.

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Aims: Determine the motility of spermatozoa in fresh goat semen after being given turmeric extract. Study Design: Randomized Block Design. Place and Duration of Study: Sample: Galang, Deli Serdang Regency, Indonesia, between December 2022 and January 2023. Methodology: Giving turmeric extract to the goat once a day. The treatment included adding 0ml, 25 ml, 50 ml, 75 ml, and 100 ml turmeric extract. The parameter observed was the percentage of motility spermatozoa in fresh goats semen. The preparation of turmeric extract, Feeding goats using turmeric extract every day at 08.0

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Al-Ghanimi, Ghada Majid, and Hamed Abdzaid Al-Khafaji. "Evaluation of the Efficiency of some Biological Control Agents in Inducing Systemic Resistance of Potato Plants Against Black Scale Disease Caused by the fungus Rhizoctonia solani Kühn." IOP Conference Series: Earth and Environmental Science 1371, no. 3 (2024): 032036. http://dx.doi.org/10.1088/1755-1315/1371/3/032036.

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Abstract The study aimed at the possibility of using safe biological agents to induce systemic resistance of potato plants against black scale disease caused by the fungus Kühn Rhizoctonia solani in In laboratory and greenhouse conditions.. Factorial experiments were carried out using a completely randomized design (CRD) with four replications for each treatment, and for four concentrations of EM1 (1, 3, 5, and 10)% and the same amount of Curcuma longa extract (1, 2, 3, and 5)% compared to the control treatment (0). The results showed that all the used concentrations of EM1 and turmeric extrac

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Febrianta, Harvey. "The Effectiveness of Turmeric Extract (Curcuma longa) to Increase The Shelf Life of Duck Meat." Social Economics and Ecology International Journal (SEEIJ) 6, no. 2 (2023): 49–52. http://dx.doi.org/10.21512/seeij.v6i2.9702.

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Duck meat is considered a healthy food because it contains various nutrients, such as protein, fat, as well as various types of vitamins and minerals, which are needed by the body. This meat can also be an option for people who don't like chicken meat. The nutritional content in duck meat is quite easy to decay. This study aims to determine the benefits of turmeric extract on sensory parameters consisting of taste, odor, and overall acceptability. Duck meat is marinated using turmeric extract with a percentage of between 2% - 6%, then stored at 4℃ for 6 days. On 0, 3rd, and 6th days the sensor

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Leray, Véronique, Benjamin Freuchet, Jérôme Le Bloc'h, Isabelle Jeusette, Celina Torre, and Patrick Nguyen. "Effect of citrus polyphenol- and curcumin-supplemented diet on inflammatory state in obese cats." British Journal of Nutrition 106, S1 (2011): S198—S201. http://dx.doi.org/10.1017/s0007114511002492.

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Among obesity-associated disorders, low-grade inflammation has been described. The putative therapeutic properties of citrus and curcumin polyphenols could be associated with their anti-inflammatory properties. Two diets supplemented either with hesperidin (0·05 %) and naringin (0·1 %) from citrus extract or with highly bioavailable curcumin from Curcuma longa extract (0·09 %) were fed to eight obese cats for two 8-week periods (cross-over study design) while maintaining animals in an obese state. Plasma acute-phase protein (APP; α1-acid glycoprotein (AGP), serum amyloid A and haptoglobin) lev

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Bouchama, Chaymae, Abdellah Zinedine, João Miguel Rocha, et al. "Effect of Phenolic Compounds Extracted from Turmeric (Curcuma longa L.) and Ginger (Zingiber officinale) on Cutaneous Wound Healing in Wistar Rats." Cosmetics 10, no. 5 (2023): 137. http://dx.doi.org/10.3390/cosmetics10050137.

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Turmeric and ginger, widely used rhizomes in culinary arts, have several beneficial biological activities, such as hypoglycemic, hepato-protective, antimicrobial, and antioxidant properties. This work investigated the effects of three phenolic extracts isolated from turmeric and ginger rhizomes on anti-inflammatory and healing properties using the solid–liquid extraction method. Wistar rats were used as a biological model. The anti-inflammatory activity was evaluated on induced edema in the rat's hind paw using carrageenan (1%). Paw volume was measured at 0 min, 45 min, 3 h, and 5 h. Treatment

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Aldiyanti, Amani, Elly Tugiyanti, and Bambang Hartoyo. "Blood Profile and Carcass Production of Broiler Chickens Given Nucleotides and Turmeric Extract in Feed." Buletin Peternakan 46, no. 4 (2022): 235. http://dx.doi.org/10.21059/buletinpeternak.v46i4.76789.

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Broiler chickens are birds that grow very fast, but have low body resistance and are easily stressed. This study aimed to examine the effect of nucleotide and turmeric extract (Curcuma longa Linn) on blood profile (erythrocytes, hemoglobin and leukocytes) and carcass production (weight of carcass, weight of breast, thighs and wings) in broiler chickens. Data was collected using a completely randomized design with 7 treatments consisting of Control: basal feed + antibiotic Bacitracin Zinc 0.1 g/day; N 0 : basal feed; N 1 : basal feed + turmeric extract 600 mg/kg feed; N 2 : basal feed + nucleot

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Kim, Hae Lim, Hae Jin Lee, Dong-Ryung Lee, Bong-Keun Choi та Seung Hwan Yang. "Anti-osteoarthritic Effects of an Herbal Composition LI73014F2 on Interleukin-1β-induced Primary Human Articular Chondrocytes". Molecules 25, № 9 (2020): 2033. http://dx.doi.org/10.3390/molecules25092033.

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Osteoarthritis (OA) is one of the most well-characterized joint diseases and is associated with chondrocyte inflammation, metalloproteinase upregulation and apoptosis. LI73014F2 is a novel composition prepared from aqueous extract of Terminalia chebula fruit, alcohol extract of Curcuma longa rhizome, and Boswellia serrata extract at 2:1:2 ratio. Earlier studies have shown that LI73014F2 inhibits cyclooxygenase-2 (COX-2), 5-lipoxygenase (5-LOX) activities, and attenuates clinical symptoms in OA subjects. In the present study, we evaluated the protective anti-inflammatory and anti-apoptotic effe

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Wu, Feipeng, Hongxia Zhao, Jiahui Shi, et al. "Preparation and evaluation of an injectable curcumin loaded chitosan/hydroxyapatite cement." Journal of Biomaterials Applications 35, no. 10 (2021): 1372–79. http://dx.doi.org/10.1177/0885328221991946.

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Curcumin (Cur) is an active ingredient of Curcuma longa. Cur has many pharmacological effects, such as anti-inflammation, anti-oxidation, anticoagulation, hypolipidemic, anti-angiogenesis and anti-cancer. An injectable curcumin loaded chitosan/hydroxyapatite bone cement (Cur-CS/HA) was prepared as a bone scaffold and drug delivery. Tween 20, a nonionic surfactant, was incorporated into the cement to improve the solubility of curcumin. Four types of Cur-CS/HA (Group0, Group1, Group5 and Group10) were prepared with different Tween 20 ratios (0, 1, 5 and 10%, respectively). The samples were chara

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Obaro, Peter Onezeyi, Osasere Enohor Obaro-Onezeyi, and Anthony Mark Dike. "Synergistic Anti-Inflammatory Effect of a Polyherbal Formulation and Palm Oil on Induced Inflammatory Models in Albino Wistar Rats." Research in Biotechnology and Environmental Science 3, no. 3 (2024): 39–45. http://dx.doi.org/10.58803/rbes.v3i3.49.

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Introduction: Palm oil obtained from the mesocarp of the fruit of Elaeis guineensis is locally used to treat inflammations either alone or in combination with herbs. The present study aimed to test the basis of using palm oil (PO) as an anti-inflammatory agent and the synergistic effect of the Aqueous Extract polyherbal Formulation (AEPHF) comprising Zingiber officinale, Curcuma longa, and Allium sativum. Materials and Methods: A total of 162 adult Wistar rats were used to investigate three anti-inflammatory models for eight weeks. Each model contained 54 rats (27 male and 27 female rats), wit

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Ling, Wang, Florenly Florenly, Liena Liena, and Dewi Riastawaty Purba. "Effectiveness of Turmeric Ethanol Extract Cream Preparation (Curcuma Longa) in Speeding up Wound Healing in Male Wistar Rats." Budapest International Research in Exact Sciences (BirEx) Journal 4, no. 1 (2021): 10–21. http://dx.doi.org/10.33258/birex.v4i1.3472.

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Injury is the loss or damage of some body tissues, due to a factor that interferes with the body's protective system. The results of several studies state turmeric rhizome extract is effective in wound healing. This study aims to find out the effect of turmeric extract (Curcuma longa) on wound healing in white rats. This type of research is experimental with the approach of Pre-test and Post-test group only control design, conducted November to December 2020. The samples used were turmeric rhizomes (Curcuma Longa) and male white rats. Determination of the size of the sample according to Federe

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Berbudi, Afiat, Muhammad Ifham Hanif, and Almahitta Cintami Putri. "Pemberian Ekstrak Curcuma Longa L. Meningkatkan Proliferasi Sel MEF yang dilakukan Scratch Test." Jurnal Vokasi Kesehatan 5, no. 1 (2019): 35. http://dx.doi.org/10.30602/jvk.v5i1.183.

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Abstract: Proliferation Enhancement of Curcuma Longa L. Extract Treatment in MEF Cell Cultres that Treated by Scratch Test. Wound prevalence is still high and becomes a problem of healing process. Improper wounds management can cause wound healing disturbance, so that the healing process will be longer. For this reason, alternative medicine is required to shorten healing process and reduce medical costs. This study aims to determine the eﬀect of Curcuma longa L. extract on enhancement of mouse embryonic fibroblast cell proliferation carried out in vitro scratch test with the research method us

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Gazala, Parveen, Basavan Duraiswamy, and Firoz Ansari. "Hexane Extract of Rhizomes of Curcuma Longa, Zingiber Officinale and Curcumine Life Span Extension in Caenorhabditis Elegans By Reducing Fat in Intestine." Med Phoenix 3, no. 1 (2018): 21–28. http://dx.doi.org/10.3126/medphoenix.v3i1.20757.

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Background: Curcumine is obtained from curcuma longa and we examined the effects of curcumin, hexane extracts of Curcuma longa and Zingiber officinale on the lifespan and aging in Caenorhabditis elegans and found that it responded to curcumin, hexane extracts of Curcuma longa and Zingiber officinale with an increased lifespan and reduced intracellular reactive oxygen species during aging.Methods: MutantStrains, culture, Curcumin and Hexane extract of Rhizomes of Curcuma longa and Zingiber officinale treatment of C. Elegan.Results: Curcumin and hexane extracts of Curcuma longa and Zingiber offi

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Nurhayani and Eko Avianto. "Antibacterial Activity of Turmeric Rhizome Extract (Curcuma longa Linn.) Against Staphylococcus aureus: A Systematic Literature Review." Open Access Indonesian Journal of Medical Reviews 2, no. 5 (2022): 276–81. http://dx.doi.org/10.37275/oaijmr.v2i5.228.

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Staphylococcus aureus is a normal flora that exists in the upper respiratory tract but can cause infection if found in amounts that are more than the normal limit (>110 CFU/ml). One of the herbal medicinal plants that is widely used in Indonesia is turmeric (Curcuma longa Linn.). Turmeric rhizome (Curcuma longa Linn.) contains active substances that have antibacterial properties, such as curcumin, flavonoids, alkaloids, saponins, and tannins. To determine the antibacterial activity of turmeric (Curcuma longa Linn.) rhizome extract against the growth of Staphylococcus aureus bacteria. This r

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Verma, Krishna Kumar, Shristi Soni, Pratiksha Pandey, Varsha Sahu, Sumit Kumar Dubey, and Neha Behar. "Comparative Evaluation of In Vitro Antimicrobial Efficacy of different Species of Curcuma against Human Pathogenic Bacteria." NewBioWorld 5, no. 1 (2023): 20–23. http://dx.doi.org/10.52228/nbw-jaab.2023-5-1-4.

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Herbal medicines have been commonly used for the treatment and prevention of disease, health promotion and for the enhancement of the life span. The Curcuma species viz., C. Roxb., C. longa Linn and C. amada are used as medicine in traditional therapeutic practices. The remedy for various diseases including cough, diabetes and hepatic disorders. The efficiency of turmeric fractions, such as petroleum ether, chloroform, benzene, methanol and aqueous were evaluated for their inhibitory effect on clinical and standard strains of pathogenic bacteria. The methanolic fraction of Curcuma longa rhizom

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CHAUHAN, AMISHA, and SHIKHA BAGHEL CHAUHAN. "FORMULATION AND EVALUATION OF POLYHERBAL EMULGEL FOR TREATMENT OF ACNE." Current Research in Pharmaceutical Sciences 12, no. 3 (2022): 132–37. http://dx.doi.org/10.24092/crps.2022.120302.

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Skin disease is a persistent inflammatory skin disorder that affects around 70% of teenage females throughout puberty. To counteract this problem, antibiotics are being administered more often, which has resulted in a variety of undesirable side effects. As a result, as a first-line topical therapy, it must target on the herbal formulation. In this study, medicinal plant extracts and oils with high antibacterial activity, such as Curcuma longa and Aloe barbadensis, tea tree oil, and lemongrass oil, were chosen to produce a polyherbal emulgel for the treatment of acne vulgaris. Curcuma longa, A

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Ogbonna, Covenant, and Erkay Özgör. "Detection of Biological Activity of Curcuma longa Methanol Extract and Its Antibacterial effect on Staphylococcus aureus." EuroBiotech Journal 5, no. 2 (2021): 56–62. http://dx.doi.org/10.2478/ebtj-2021-0009.

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Abstract Plants are known to possess enormous profound benefits, which if well incorporated in daily living have the potential to influence our health in ways unexpected. Significant progress has been made concerning the anti-oxidative and anti-cancerous effect of bioactive components in food products, worthy of note in the curcuminoids derived from turmeric (Curcuma longa) rhizomes. Therefore, to this end, this research aims to describe succinctly the phytocomponents, antioxidant activity and anti-microbial activity of turmeric methanol extract. The zones of inhibition were measured after pla

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Aseptianova, Aseptianova. "PENGARUH EKSTRAK DAUN KUNYIT (Curcuma longa Linn.) SEBAGAI INSEKTISIDA ELEKTRIK TERHADAP MORTALITAS NYAMUK Culex sp. L." Pro-Life 6, no. 1 (2019): 44. http://dx.doi.org/10.33541/pro-life.v6i1.937.

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Mosquito Culex sp. L. is a vector of elephantiasis disease, prevention effort of elephantiasis vector is usually done by using chemical and natural insecticide. In the leaves of turmeric can be used as a natural insecticide in the prevention of elephantiasis vector disease. The objectives of this research are (1) to know the effect of turmeric extract ((Curcuma longa Linn.) As electrical insecticide to mortality of Culex sp. L. (2) To know the concentration of turmeric extract (Curcuma longa Linn.) Which is effective to be used as an electric insecticide against mortality of Culex sp. L. expre

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V.K., Vinaya, Jishnu B., Hima K. M., et al. "Evaluation of Curcuma longa Extract as a Natural Alternative to Eosin Stain for Hemoparasite Diagnosis." Journal of Advances in Microbiology 25, no. 5 (2025): 21–28. https://doi.org/10.9734/jamb/2025/v25i5930.

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Curcuma longa L., a medicinal herb from the Zingiberaceae family, is widely known for its antioxidant, anti-inflammatory, hepatoprotective, and antimicrobial properties. This study evaluates the efficacy of C. longa extract as an eco-friendly, cost-effective, and sustainable alternative to eosin for staining blood smears, specifically for detecting Babesia gibsoni. Ethanolic extraction was performed using 70% ethanol as a solvent to obtain the dye from C. longa rhizomes. Blood smears were stained with different concentrations of the extract and counterstained using various methods. The highest

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Mulyani, Yani, Patonah Hasimun, and Siti Nurjanah. "Subcrhonic Toxicity of Curcuma longa (Tumeric) Rhizoma Extract on Rats." Majalah Obat Tradisional 27, no. 2 (2022): 111. http://dx.doi.org/10.22146/mot.72259.

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Toxicity is a condition that indicates a harmful effect contained in a substance such as turmeric, which is an effective traditional medicinal plant used for antihypertensive treatment. Therefore, this study aims to determine the effect of repeated dosing of turmeric (Curcuma longa L.) rhizome extract. This subchronic toxicity study was divided into 4 groups, namely 1 normal treated with 0.5% Na-CMC, and 3 treatments with turmeric extract at doses of 50, 100, and 200 mg/kg BW for 28 days with each group consisting of 5 males and 5 female Wistar rats. The results showed that the turmeric extrac

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Amagon, Kennedy Iliya, David Agyo, Leritshimwa Amagon, and Ernest Magani Wanche. "Toxicity and <i>in vitro</i> antioxidant potential of <i>Curcuma longa</i> Linn and <i>Zingiber officinale</i> Rosc rhizomes in <i>Drosophila melanogaster</i>." Journal of Pharmacy & Bioresources 20, no. 3 (2023): 125–33. http://dx.doi.org/10.4314/jpb.v20i3.4.

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Medicinal plants like Curcuma longa and Zingiber officinale contain phytochemicals which have antioxidant properties. The study evaluated the antioxidant effect of Curcuma longa and Zingiber officinale on the survival of Drosophila melanogaster administered isoniazid. Drosophila melanogaster aged 3-5 days old were exposed to different concentrations (5-1000 mg/ 5 g diet) of isoniazid, and extract for 7 days to determine the lethal concentration (LC50). A 14-day survival assay was performed to evaluate the effect of isoniazid and the herbal extract on the survival rate of Drosophila melanogaste

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Awode, A. U., G. M. Dalyop, S. D. Olatidoye, S. Tijani, I. H. Kalu, and O. Adeyanju. "Extraction, Chemical Modification and Characterization of Turmeric Dye (Curcuma longa) and its Application on Cotton Fabric." International Journal of Research and Innovation in Applied Science VIII, no. VII (2023): 124–28. http://dx.doi.org/10.51584/ijrias.2023.8713.

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Curcuma longa is a tropical plant whose rhizomes has been used to dye cloth since at least 2500 BCE but being a natural dye, it has poor to moderate fastness. In this study, an attempt was made to extract turmeric dye from Curcuma longa rhizomes and carry out its chemical modification by the choline chloride method to improve its fastness property when applied to fabrics. Turmeric dye was extracted from the rhizome using acetone and further crystallized with hexane to form the curcumin, the concentrated yellow dye. The characterization of the extracted dye and modified dye was carried out usin

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Astuti, Siswi, Nanik Astuti Rahman, and Endah Kusuma Rastini. "POTENTIAL OF CURCUMA LONGA EXTRACT TO THE GROWTH OF SALMONELLA STAPHYLOCOCCUS AND BACILLUS SUBSTILIS ON PELOR EXTRACT." Journal of Sustainable Technology and Applied Science (JSTAS) 1, no. 2 (2020): 9–14. http://dx.doi.org/10.36040/jstas.v1i2.3020.

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People with autism are sensitive to milk protein (casein), gluten, and sugar. These foods can cause an increase in aggressive behavior, crying, anger, stress and depression, while also able to increase digestive disorders, allergies and neurobiological disorders in people with autism. Trials have been carried out on several autistic people by providing food based on MOCAF modified with Centella Asiatica extract with positive results. Children are more focused, more communicative and the symptoms of stress and depression decrease. The weakness is that it can still lack the necessary vitamins an

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Marques Meccatti, Vanessa, Larissa de Souza Moura, Juliana Guerra Pinto, et al. "Curcuma longa L. Extract and Photodynamic Therapy are Effective against Candida spp. and Do Not Show Toxicity In Vivo." International Journal of Dentistry 2022 (July 1, 2022): 1–6. http://dx.doi.org/10.1155/2022/5837864.

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Radiotherapy induces a higher level of Candida spp. colonization, resulting in oral candidiasis. This study aimed to evaluate the phototransformation potential of the glycolic extract of Curcuma longa (C. longa); the antifungal activity of C. longa, curcumin, and antifungal photodynamic therapy (aPDT) with blue light-emitting diodes “LED” on Candida albicans and Candida tropicalis in vitro; and the toxicity of C. longa and curcumin in Galleria mellonella model. In order to confirm the light absorption capacity of the C. longa extract, its phototransformation potential was evaluated. The antifu

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Aminuddin, Muhammad, Djanggan Sargowo, Teguh Sardjono та Widjiati Widjiati. "Curcuma longa supplementation reduce MDA, TNF-α, and IL-6 levels in a rat model exposed to soot particulates". Open Veterinary Journal 13, № 1 (2023): 11. http://dx.doi.org/10.5455/ovj.2023.v13.i1.2.

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Background: Particulate Matter (PM) is one of the important components in air pollution that can cause endothelial vascular dysfunction through exacerbation of atherosclerosis and inflammation of the respiratory system. Increased levels of MDA in blood plasma can be an indicator of oxidative stress. Then, macrophages can secrete proinflammatory cytokines will stimulate immune cells and vascular endothelial cells to release inflammatory cytokines, such as interleukin-6 (IL-6) and tumor necrotic factor-α (TNF-α). Curcuma longa works by scavenging the active free radicals involved in the peroxida

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Pathak, NN, SR Rajurkar, S. Tarekh, and VV Badgire. "Nephroprotective Effects of Carvedilol and Curcuma longa against Cisplatin-Induced Nephrotoxicity in Rats." Asian Journal of Medical Sciences 5, no. 2 (2013): 91–98. http://dx.doi.org/10.3126/ajms.v5i2.5483.

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Objective: Goal of this study is to investigate the effects of carvedilol (5 mg/kg, p.o), aqueous and methanolic extract of Curcuma longa (500mg/kg, p.o) against cisplatin induced renal damage in Wistar rats after a single intraperitoneal injection of 7.5mg- 1. Methods: Wistar rats were randomly divided into 7 groups (n=10). Rats in group I were normal control received normal saline (5 ml/kg; i. p.) on day zero, while group VIa and VIb were vehicle control, received carboxymethyl cellulose (2.5 ml/kg; p.o.) and propylene glycole (2.5 ml/kg, p.o.) respectively from day 3 to 17. Renal toxicity w

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NN Pathak, SR Rajurkar, S Tarekh, and VV Badgire. "Nephroprotective Effects of Carvedilol and Curcuma longa against Cisplatin-Induced Nephrotoxicity in Rats." Asian Journal of Medical Sciences 5, no. 2 (2013): 91–98. https://doi.org/10.71152/ajms.v5i2.3329.

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Objective: Goal of this study is to investigate the effects of carvedilol (5 mg/kg, p.o), aqueous and methanolic extract of Curcuma longa (500mg/kg, p.o) against cisplatin induced renal damage in Wistar rats after a single intraperitoneal injection of 7.5mg- 1. Methods: Wistar rats were randomly divided into 7 groups (n=10). Rats in group I were normal control received normal saline (5 ml/kg; i. p.) on day zero, while group VIa and VIb were vehicle control, received carboxymethyl cellulose (2.5 ml/kg; p.o.) and propylene glycole (2.5 ml/kg, p.o.) respectively from day 3 to 17. Renal toxicity w

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Pandey, Jyoti, Suman Mishra, and Kamal Jaiswal. "IN VITRO EVALUATION OF THE ANTHELMINTIC ACTIVITY OF RHIZOME EXTRACTS OF CURCUMA LONGA (LINN.)." Asian Journal of Pharmaceutical and Clinical Research 11, no. 12 (2018): 425. http://dx.doi.org/10.22159/ajpcr.2018.v11i12.28313.

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Objective: The current study was carried out to evaluate the anthelmintic activity of the rhizome extract of Curcuma longa as an alternative source of effective remedies for nematodiasis.Methods: The anthelmintic activity of the C. longa was assessed in vitro against Haemonchus spp., a gastrointestinal (abomasum) parasite of goats. Different concentrations of the extracts (1 mg/mL, 2.5 mg/mL, 5 mg/mL, and 10 mg/mL) in phosphate-buffered saline (PBS) were tested, and the results expressed in terms of time of paralysis (minute) and time of death (minute) of the worms. Albendazole (1 mg/mL) was u

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Fajariyah, Susantin, Eva Tyas Utami, Mahriani A, and Erviana Effendi. "EFFECTS OF TURMERIC (CURCUMA LONGA L.) RHIZOME EXTRACT ONLUNGHISTOLOGICAL STRUCTUREIN MICE(MUSMUSCULUSL) INDUCEDNICOTINE." International Journal of Advanced Research 11, no. 05 (2023): 1110–15. http://dx.doi.org/10.21474/ijar01/16972.

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Nicotine is an alkaloid compound found in tobacco leaves. The use of nicotine in a long period can cause lung damage.The aim of this study was to determine the effect of giving turmeric extract (Curcuma longa L.) on lung histological structure in nicotine-induced mice. In this study, 25 male mice were divided into 5 groups. Group 1 was a negative control group without nicotine-induced and turmeric extract. Group 2 was a positive control group induced by nicotine without turmeric rhizome extract, groups 3, 4 and 5 were groups exposed to nicotine followed by giving turmeric extract at doses of 0

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Czernicka, Lidia, Agnieszka Grzegorczyk, Zbigniew Marzec, Beata Antosiewicz, Anna Malm, and Wirginia Kukula-Koch. "Antimicrobial Potential of Single Metabolites of Curcuma longa Assessed in the Total Extract by Thin-Layer Chromatography-Based Bioautography and Image Analysis." International Journal of Molecular Sciences 20, no. 4 (2019): 898. http://dx.doi.org/10.3390/ijms20040898.

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Curcuma longa from Zingiberaceae belongs to the major spices consumed around the world, known from its cholagogue, anti-inflammatory, and antimicrobial properties. Lack of data on the activity of single components of turmeric extract encouraged the authors to apply TLC (thin-layer chromatography) based bioautography studies to reveal its antimicrobial constituents and construct a universal platform for the bioactivity assessment of crude extracts, with help of a freeware ImageJ software. This optimized chromatographic bioassay performed on diethyl ether and methanol extracts of Curcuma longa w

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Baizuroh, Ning, Yahdi Yahdi, and Yuli Kusuma Dewi. "Uji Kualitas Hand Sanitizer Ekstrak Daun Kunyit (Curcuma Longa Linn)." al-Kimiya 7, no. 2 (2020): 88–94. http://dx.doi.org/10.15575/ak.v7i2.8744.

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Diare merupakan penyakit yang diakibatkan oleh berbagai jenis bakteri salah satunya bakteri Escherichia coli dan Staphylococcus aureus. Hand sanitizer merupakan antiseptik yang dapat membunuh bakteri karena mengandung alkohol dan triklosan. Selain itu, daun kunyit mempunyai senyawa metabolit sekunder seperti flavonoid, terpenoid, triterpenoid tanin, dan saponin, yang berperan sebagai antibakteri. Hand sanitizer ekstrak daun kunyit dibuat dengan cara memberikan variasi volume pada ekstrak daun kunyit sebanyak 0 mL, 5 mL, 10 mL, 15 mL, dan 20 mL, kemudian di uji dengan uii organoleptik, uji visk

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Fauzan, Laili Shafarina, Masfufatun Masfufatun, and Inawati Inawati. "Pengaruh Ekstrak Etanol Kunyit (Curcuma longa) terhadap Pembentukan Biofilm Candida albicans." JI-KES (Jurnal Ilmu Kesehatan) 6, no. 2 (2023): 215–20. http://dx.doi.org/10.33006/jikes.v6i2.481.

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Abstrak Kunyit (curcuma longa) merupakan salah satu jenis tanaman yang memiliki zat bioaktif yang dapat menghambat jamur. Penelitian ini bertujuan untuk mempelajari aktivitas antibiofilm ekstrak kunyit yang dapat menghambat pertumbuhan biofilm Candida albincans. Jenis penelitian menggunakan eksperimental labolatorik secara in vitro dengan rancangan penelitian post-test only control group. Kunyit dimaserasi dengan pelarut etanol. Ekstrak dibuat menjadi konsentrasi 1%; 0,5%; 0,25%; 0,125% dan 0,625%. Uji antibiofilm menggunakan metode mikrodilusi yang diawali dengan tahap adherent sel dan ditamb

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Abdel-Shafy, Sobhy, Abdullah D. Alanazi, Hanan S. M. Gabr, et al. "Efficacy and safety of ethanolic Curcuma longa extract as a treatment for sand tampan ticks in a rabbit model." April-2020 13, no. 4 (2020): 812–20. http://dx.doi.org/10.14202/vetworld.2020.812-820.

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Background and Aim: The soft tick Ornithodoros savignyi is distributed throughout Africa, including Egypt. It primarily attacks camels, cattle, donkeys, and cows; and rarely affects humans. This study evaluated the acaricidal efficacy of ethanolic Curcuma longa extract (Turmeric) on the second nymphs of O. savignyi and then investigated the safety of this herb in rabbits. Materials and Methods: The nymphs were immersed in 10, 5, 2.5, 1.25, and 0.625 mg/ml ethanolic C. longa extract. An additional group was immersed in ethanol as a control. On the 1st, 7th, and 15th-day post-treatment, the mort

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Haq, Nazrul, Faiyaz Shakeel, Mohammed M. Ghoneim, et al. "Greener Stability-Indicating HPLC Approach for the Determination of Curcumin in In-House Developed Nanoemulsion and Curcuma longa L. Extract." Separations 10, no. 2 (2023): 98. http://dx.doi.org/10.3390/separations10020098.

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Despite the fact that several analytical methodologies have been reported for the determination of curcumin (CCM) in a wide range of sample matrices, the greener liquid chromatographic approaches to determine CCM are scarce in the literature. Therefore, this research is designed to develop and validate a greener stability-indicating “high-performance liquid chromatography (HPLC)” methodology to determine CCM in an in-house developed nanoemulsion, Curcuma longa L. extract, and commercial tablets. CCM was measured on a Nucleodur (150 mm × 4.6 mm) RP C18 column with 5 µm-sized particles. Ethanol

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DORNELES, KEILOR DA ROSA, PAULO CESAR PAZDIORA, FÁBIO JÚNIOR ARAÚJO SILVA, RENATA MOCCELLIN, and CÂNDIDA RENATA JACOBSEN FARIAS. "CONTROL OF Bipolaris oryzae (Breda de Haan) USING Curcuma longa (Linnaeus) EXTRACT AND EFFECT OF THIS EXTRACT ON RICE SEED PHYSIOLOGY." Revista Caatinga 31, no. 1 (2018): 99–105. http://dx.doi.org/10.1590/1983-21252018v31n112rc.

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ABSTRACT This study was conducted to evaluate the use of Curcuma longa (Linnaeus) extract in the in vitro control of Bipolaris oryzae (Breda de Haan) and to characterize the effect of this extract on rice seed germination. A completely randomized arranged in a factorial experimental design was used: three isolates of B. oryzae from rice seed from different rice-growing regions of Rio Grande do Sul (Fronteira Oeste, Campanha, and Sul) were tested with three concentrations (20, 40, and 80 mg/mL) of C. longa plus a control treatment (0 mg/mL). Each reaction was repeated in quadruplicate. The effe

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Minh, N. P. "Application of red onion (Allium ascalonicum) and turmeric (Curcuma longa) rhizome extract in feed of black tiger shrimp (Penaeus monodon) and white leg shrimp (Litopenaeus vannamei) aquaculture." Food Research 9, no. 3 (2025): 1–7. https://doi.org/10.26656/fr.2017.9(3).108.

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Red onion (Allium ascalonicum) bulb and turmeric (Curcuma longa) rhizome are important crops with high economic value. The present research aimed to evaluate the application of red onion (Allium ascalonicum) extract (6, 9, 12, 15, 18 g/kg diet) combined with turmeric (Curcuma longa) rhizome extract (2, 4, 6, 8, 10 g/kg diet) in a basal diet on growth performance, survival rate and feed utilization of black tiger shrimp (Penaeus monodon) and white leg shrimp (Litopenaeus vannamei). A total of 240 kg of black tiger shrimp (initial weight 150±10 g) and 240 kg of white leg shrimp (initial weight 5

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Mardaneh, Jalal, Hamid Beyzaei, Seyed Hadi Hashemi, Behzad Ghasemi, and Abbas Rahdar. "Comparative Evaluation of the Inhibitory Potential of Synthetic N-Heterocycles, Cu/Fe3O4@SiO2 Nanocomposites and Some Natural Products against Non-Resistant and Antibiotic-Resistant Acinetobacter baumannii." Pharmaceutical Sciences 26, no. 2 (2020): 184–92. http://dx.doi.org/10.34172/ps.2020.12.

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Background: Acinetobacter baumannii is a common infectious agent in hospitals. New antimicrobial agents are identified and prepared to combat these bacterial pathogens. In this context, the blocking potentials of a series of synthesized N-heterocyclic compounds, Cu/Fe3O4@SiO2 nanocomposites, glycine, poly-L-lysine, nisin and hydroalcoholic extracts of Trachyspermum ammi, Curcuma longa and green tea catechins were evaluated against non-resistant and multidrug-resistant strains of A. baumannii. Methods: Solutions of heterocyclic derivatives and hydroalcoholic extracts of Trachyspermum ammi, Curc

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Biquio, Louie Jay T., Clutha C. Pongan, Renz Ivan M. Sabado, et al. "Assessment of In vitro Potential of Turmeric Crude Extract Against Klebsiella pneumoniae on Smoked Nile Tilapia (Oreochromis niloticus)." UTTAR PRADESH JOURNAL OF ZOOLOGY 45, no. 24 (2024): 184–91. https://doi.org/10.56557/upjoz/2024/v45i244723.

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This study investigated the potential of turmeric (Curcuma longa) crude extract to inhibit Klebsiella pneumoniae in smoked Nile tilapia. Initial tests showed that 5.0 mL of a 0.5 g/mL extract concentration exhibited significant antibacterial activity, resulting in a marked reduction in bacterial growth compared to other treatments. To confirm its effectiveness, the optimal extract from the preliminary test was applied to smoked fish experimentally infected with Klebsiella pneumoniae. The results indicated that the optimal extract had fewer bacterial count up to Day 5 as compared to control, bu

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Pramayastri, Vina, Endang Mahati, Mohammad Sulchan, and Diana Afifah. "Effects of catfish oil and Curcuma longa L. extract on ApoB levels and atherosclerosis risk indicators in metabolic syndrome rats." Journal of Advanced Biotechnology and Experimental Therapeutics 7, no. 2 (2024): 408. http://dx.doi.org/10.5455/jabet.2024.d35.

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The increase in ApoB levels, atherogenic index of plasma (AIP) and castelli risk index I-II (CRI) is prediction of cardiovascular disease in metabolic syndrome. Lipid peroxidation could initiate the process of atherosclerosis and involved in the etiology of cardiovascular disease. Dietary fish oil and extract of Curcuma has been shown to beneficially reducing effect of atherosclerosis and lipid peroxidation. The aim of this study was to determine the effect of Catfish Oil and Curcuma longa Linn extract on ApoB levels and lipid ratios as protective nutraceutical for metabolic syndrome. Thirty m

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John, Ohiagu Chukwuemeka, Achi Ngozi Kalu, Ohaeri Obioma Christopher, and Osuji Chigozirim Amarachi. "Phytochemical Composition and Toxicological Profiling of Curcuma longa (Turmeric) Root Extract in Rats." International Journal of Biochemistry Research & Review 33, no. 1 (2024): 1–12. http://dx.doi.org/10.9734/ijbcrr/2024/v33i1847.

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Background: Curcuma longa Linn (turmeric) is a common medicinal plant used in Africa for the treatment of diseases. In this study, its extract was evaluated to ascertain its phytochemical composition and toxicity in wistar rats. Methods: The prepared rhizome ethanol extract was first subjected to preliminary phytochemical evaluation and then lethal dose (LD50) test. In the sub-acute toxicity test, 20 adult wistar rats assigned to 4 groups of 5 rats each were administered oral graded doses of the extract. Group 1 served as control while groups 2, 3 and 4 received 250, 500 and 1000 mg/kg b

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Kim, Jeong Ah, Jong Keun Son, Hyun Wook Chang, et al. "Inhibition of Mushroom Tyrosinase and Melanogenesis B16 Mouse Melanoma Cells by Components Isolated from Curcuma longa." Natural Product Communications 3, no. 10 (2008): 1934578X0800301. http://dx.doi.org/10.1177/1934578x0800301014.

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The methanol extract of the rhizomes of Curcuma longa was found to inhibit tyrosinase activity. After partition, various column chromatographic and preparative HPLC procedures were used for bioassay guided isolation from the active ethyl acetate-soluble fraction. Various spectroscopic (1D-, 2D-NMR) and mass spectrometric techniques, and Mosher's esterification were applied to elucidate the structures of the isolated compounds. The isolates were tested using an in vitro mushroom tyrosinase assay. Inhibition of melanin formation by the active compounds was further evaluated using B16 mouse melan

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H., Baqer,, Salah Gatea, Salam Altaie, and Thamer ALjanabi. "Growth performance of broiler chickens of turmeric (Curcuma longa) turmeric aqueous extract." Bionatura 8, no. 4 (2023): 1–7. http://dx.doi.org/10.21931/rb/2023.08.04.79.

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The effects of Turmeric Powder extract (TPE) on the growth performance of broiler chicken were evaluated in the 5-week study. On 240-day-old chicks weighing 40.9g, levels were supplemented with turmeric powder extracts (TPE) in the water of broiler chicken. In conclusion, there was increased final live weight and weight gain, a better feed conversion ratio (FRC), and body and feed intake with the highest TPE on water. The serum metabolites were not affected by the level of TP in the diets. It was concluded that levels supplemented with turmeric powder Extracts (TPE) in the water of broiler chi

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A. B., Ogunjesa,, and Odesanmi, M. B. "Impact of Boiling on Composition of Oven-Dried Curcuma Longa Linn Rhizomes." African Journal of Agriculture and Food Science 7, no. 4 (2024): 201–10. http://dx.doi.org/10.52589/ajafs-4rljoqek.

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The effect of boiling Curcuma longa Linn rhizomes prior to oven drying on its proximate, mineral and phytochemical composition was studied. Fresh turmeric rhizomes were sliced to 5 mm thickness and then divided into two parts. The first part was oven dried directly while the second part was boiled prior to oven drying. Both products were then pulverised and subjected to laboratory analysis following standard procedures of AOAC and spectrometry. Boiling had an impact on the proximate composition as there were significant (P<0.05) reductions in ether extract, crude fibre and crude protein. So

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Pujimulyani, Dwiyati, Wisnu Adi Yulianto, Bayu Kanetro, et al. "Properties of Turmeric (Curcuma longa L.) from Indonesia and Philippines." IOP Conference Series: Earth and Environmental Science 1460, no. 1 (2025): 012043. https://doi.org/10.1088/1755-1315/1460/1/012043.

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Abstract One of the ingredients that can be used for herbal medicines is the Curcuma longa L. rhizome. Citric acid as a blanching medium is reported to be able to chelate metals. This research aimed to determine the antioxidative properties of Curcuma longa L. from Indonesia and the Philippines with pressurized blanching treatment. These steps of the research of Curcuma longa: sorting, peeling, washing, pressurized blanching at a temperature of 120 °C with variations in blanching time of 0, 2.5, 5, 7 minutes, slicing, drying, grinding, sieving, and obtaining powder. The powder of Curcuma longa

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Isaiah, Israel Bakenneso, Sunday Musa, Abubakar Adamu Sadeeq, and Ubong Ekpo. "N-Butanol Fraction of Curcuma Longa (Turmeric) Ameliorates Lead Acetate-Induced Altered Sensory Motor Activity, Oxidative Stress and Histopathological Changes in the Frontal Cortex of Wistar Rat Pups." Journal of Neurobehavioral Sciences 11, no. 3 (2024): 109–16. https://doi.org/10.32739/jnbs.11.1608188.

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Background: Lead acetate (Pb) exposure during frontal cortex development is associated with developmental toxicity later in life, causing both morphological and functional alterations. Curcuma longa, however, has been suggested to possess neuroprotective qualities that could lessen these adverse effects. Objective: Assessed the frontal cortex following treatment with Curcuma longa. Materials and Methods: Twenty adult female Wistar rats and ten adult male Wistar rats were matched during the proestrous phase of the estrous cycle in order to mate and create five groups of six (n=6) in a 4:2 (4 fe

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Essien, Nsimah Monday, Ofem Effiom Eteng, Thomas Nku-Ekpang Okot-Asi, Nseobong O. Bassey, Joe Enobong Essiet, and Mbeh Ubana Eteng. "Rejuvenating potentials of Curcuma longa on Sudan IV dye induced hepato-renal injury." Calabar Journal of Health Sciences 6 (April 29, 2022): 8–14. http://dx.doi.org/10.25259/cjhs_32_2021.

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Objectives: Sudan IV dye (S4D), has been reported to enhance the color of food products example palm oil, despite the health issues associated with these colorants. The potent antioxidant attribute of Curcuma longa facilitates its capacity to protect the kidney against deleterious attacks by free radicals. This study investigated the rejuvenating potentials of the extract of C. longa by S4D induced hepato-renal injury in rats. Material and Methods: Twenty-five female albino rats were distributed into five groups, as follows: Group 1 received distilled water and diet only, Group 2 received 10%

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Aldayel, Munirah F. "Enhancement of the Bioactive Compound Content and Antibacterial Activities in Curcuma Longa Using Zinc Oxide Nanoparticles." Molecules 28, no. 13 (2023): 4935. http://dx.doi.org/10.3390/molecules28134935.

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Incorporating nanoparticles into plant cultivation has been shown to improve growth parameters and alter the bioactive component compositions of many plant species, including Curcumin longa. The aim of the current study was to investigate the effects of foliar application of zinc oxide nanoparticles on the content of bioactive compounds and their antibacterial activities against potential bacterial pathogens. To this end, C. longa leaves were treated with different doses of ZnO NPs to see how this affected their bioactive component composition. The effect of different doses of ZnO NPs on the a

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