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Journal articles on the topic 'Cutaneous carcinoma'

Author: Grafiati

Published: 8 June 2024

Last updated: 31 July 2025

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1

Puri, Neerja, Sukhmani Kaur Brar, and B. K. Brar. "A study on the cutaneous manifestations of an internal malignancy in a tertiary care center in North India." Our Dermatology Online 12, no. 2 (2021): 140–44. http://dx.doi.org/10.7241/ourd.20212.7.

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Introduction: Cutaneous metastases may precede a malignancy and, in other cases, herald the recurrence of a malignancy after surgery. Aim: To determine the significance of cutaneous manifestations in patients with an internal malignancy and to observe the various types of carcinomas in patients attending a dermatology OPD. Methods: This was a prospective hospital-based study undertaken to observe the cutaneous features in a dermatology OPD in patients coming from the oncology department of a medical college. Results: The commonest malignancy in males was a lung carcinoma, observed in 5.50% of

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2

Novice, Taylor Shea, David Oberlin, and Chauncey McHargue. "A case of cutaneous metastatic adenosquamous carcinoma of the cervix." SKIN The Journal of Cutaneous Medicine 3, no. 4 (2019): 271–74. http://dx.doi.org/10.25251/skin.3.4.7.

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Introduction:Cutaneous metastasis of cervical carcinoma is very rare, with a reported incidence of .1 to 2%. The adenosquamous carcinoma subtype has been reported the least.3-5 We present a case report of ulceronodular cutaneous metastasis of adenosquamous carcinoma of the cervix.Case Description:A 50-year-old African American female with an eleven-year history of metastatic adenosquamous carcinoma of the cervix presented to the emergency department with an asymptomatic rash in her groin for one-month duration. On physical exam, there were hyperpigmented to violaceous papulonodules across the

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3

Onak Kandemir, Nilufer, Figen Barut, Kıvanç Yılmaz, Husnu Tokgoz, Mubin Hosnuter, and Sukru Oguz Ozdamar. "Renal Cell Carcinoma Presenting with Cutaneous Metastasis: A Case Report." Case Reports in Medicine 2010 (2010): 1–5. http://dx.doi.org/10.1155/2010/913734.

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Renal cell carcinoma is the most common kidney tumor in adults. Cutaneous metastasis is a rare first symptom of the disease. This paper describes the diagnosis of a renal cell carcinoma that was indicated by cutaneous metastasis in the head and neck region, and considers the etiopathogenesis of such cases. A careful skin examination is important to detect cutaneous metastasis associated with renal cell carcinomas. Metastatic skin lesions in the head and neck region must be taken into consideration during a differential diagnosis.

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4

Binsheikhan, S., S. Mittal, and M. Al Abadie. "Nevoid Basal Cell Carcinoma Syndrome (Gorlin Syndrome) in Children." European Journal of Medical and Health Sciences 3, no. 5 (2021): 15–17. http://dx.doi.org/10.24018/ejmed.2021.3.5.888.

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Introduction: Gorlin syndrome or nevoid basal cell carcinoma syndrome (NBCCS) is a rare genetic disorder characterised by development of multiple basal cell carcinomas (BCC) at a young age. Case report: A 7 year female child presented with MULTIPLE skin growths on the neck, face and upper chest for 3 years, with prominent forehead and mild non-scarring alopecia. She also had a history of medulloblastoma treated 3 years ago. There was no significant family history. Biopsy from one of the lesions showed basal cell carcinoma (BCC). Discussion: Nevoid basal cell carcinoma syndrome (NBCCS) is an au

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Binsheikhan, S., S. Mittal, and M. Al Abadie. "Nevoid Basal Cell Carcinoma Syndrome (Gorlin Syndrome) in Children." European Journal of Medical and Health Sciences 3, no. 5 (2021): 15–17. http://dx.doi.org/10.24018/ejmed.2021.3.5.888.

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Introduction: Gorlin syndrome or nevoid basal cell carcinoma syndrome (NBCCS) is a rare genetic disorder characterised by development of multiple basal cell carcinomas (BCC) at a young age. Case report: A 7 year female child presented with MULTIPLE skin growths on the neck, face and upper chest for 3 years, with prominent forehead and mild non-scarring alopecia. She also had a history of medulloblastoma treated 3 years ago. There was no significant family history. Biopsy from one of the lesions showed basal cell carcinoma (BCC). Discussion: Nevoid basal cell carcinoma syndrome (NBCCS) is an au

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6

Knuutila, Jaakko S., Olli Kaijala, Salla Lehto, et al. "Clinical Risk Factors for Cutaneous Squamous Cell Carcinoma in Patients with Actinic Keratosis or Cutaneous Squamous Cell Carcinoma in Situ: A Retrospective Double-cohort Study." Acta Dermato-Venereologica 104 (November 27, 2024): adv40990. http://dx.doi.org/10.2340/actadv.v104.40990.

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Actinic keratosis and cutaneous squamous cell carcinoma in situ are precancerous forms of cutaneous squamous cell carcinoma. In this single-centre retrospective study, patients with histopathologically confirmed actinic keratosis (n = 121) or cutaneous squamous cell carcinoma in situ (n = 99) as their initial keratinocyte-derived lesion were compared and evaluated with regard to development of cutaneous squamous cell carcinoma during a 5-year observation period. Patients with severely dysplastic actinic keratosis or cutaneous squamous cell carcinoma in situ as their initial lesion developed cu

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7

Moreno de Oliveira Fernandes, Tânia Rita, Ricardo Santana de Lima, Ana Kívia Silva Matias, Leonardo Pereira de Souza Alves, and Marcus Vinícius Solano Ferreira de Souza. "Cutaneous Metastasis as the Presenting Sign of Urothelial Carcinoma." Journal of the Portuguese Society of Dermatology and Venereology 78, no. 3 (2020): 255–59. http://dx.doi.org/10.29021/spdv.78.3.1203.

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Cutaneous metastases of visceral neoplasms are rare conditions, and urothelial or transitional cell carcinomas are responsible for less than 1% of cases. We report the case of a 50-year-old male patient who progressively developed multiple cutaneous nodules on his head, abdomen, axilla, and groin, some with ulceration. Skin biopsy and immunohistochemistry were consistent with cutaneous metastasis of urothelial carcinoma. Computed tomography scan revealed generalized metastasis in internal organs. In this rare case, cutaneous metastases were the presenting sign of the disease and, as reported,

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8

Vandeweyer, Eric, François Sales, and Rika Deraemaecker. "Cutaneous verrucous carcinoma." British Journal of Plastic Surgery 54, no. 2 (2001): 168–70. http://dx.doi.org/10.1054/bjps.2000.3440.

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9

Pleat, Jonathon, Lisa Sacks, and Howard Rigby. "Cutaneous verrucous carcinoma." British Journal of Plastic Surgery 54, no. 6 (2001): 554–55. http://dx.doi.org/10.1054/bjps.2001.3639.

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10

Pazzini, Renato, Gustavo A. Pereira, and Ricardo S. Macarenco. "Cutaneous Metaplastic Carcinoma." American Journal of Dermatopathology 40, no. 7 (2018): e100-e103. http://dx.doi.org/10.1097/dad.0000000000001070.

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11

Asuquo, Maurice E., Mark S. Umoh, and Ekpo E. Bassey. "Cutaneous Metastatic Carcinoma." Advances in Skin & Wound Care 23, no. 2 (2010): 77–80. http://dx.doi.org/10.1097/01.asw.0000363504.92360.5f.

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12

Mukhtiar, Ayesha, and Sarbar Napaki. "Cutaneous apocrine carcinoma." Pathology 56 (February 2024): S67. http://dx.doi.org/10.1016/j.pathol.2023.12.229.

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13

Sivaramakrishnan, S., and Jayakar Thomas. "Cutaneous horn arising from a basal cell carcinoma of forehead: a case report." International Journal of Research in Dermatology 5, no. 1 (2019): 210. http://dx.doi.org/10.18203/issn.2455-4529.intjresdermatol20190248.

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<p class="abstract">The term cutaneous horn or “cornu cutaneum” is used to describe a well circumscribed usually conical hyperkeratotic mass arising from another cutaneous lesion. Several lesions have been reported to occur at the base of the keratin mass. Here we report a rare case of cutaneous horn arising from a basal cell carcinoma (BCC) over the forehead of a 52 year old female patient.</p><p class="abstract"> </p>

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14

Sadr, AH, S. de Kerviler, and N. Kang. "Cutaneous basal cell carcinoma with endobronchial metastasis." Annals of The Royal College of Surgeons of England 96, no. 7 (2014): e20-e21. http://dx.doi.org/10.1308/003588414x13946184902244.

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Although basal cell carcinoma is a very common malignancy, metastasis from this tumour is extremely rare. For this reason, many plastic surgeons, dermatologists and physicians dealing with skin malignancies consider this as a locally invasive malignancy. We present a rare case of metastatic basal cell carcinoma manifested as a bronchial tumour. This case highlights the fact that despite basal cell carcinoma’s local invasive potential, the possibility of distant metastasis still exists and clinicians should therefore be cautious about interpreting extracutaneous symptoms. Chest physicians shoul

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15

Requena, Luis, Antonio Aguilar, Guadalupe Renedo, et al. "Tripe Palms: A Cutaneous Marker of Internal Malignancy." Journal of Dermatology 22, no. 7 (1995): 492–95. http://dx.doi.org/10.1111/j.1346-8138.1995.tb03430.x.

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AbstractTripe palms is a distinctive paraneoplastic cutaneous sign which is frequently associated with internal malignancy, specially carcinomas of the lung and stomach. We describe a patient with ovary carcinoma who showed a curious rugose thickening of the palms with accentuation of the normal dermatoglyphic ridges. The lesions were a specially prominent on the fingertips. The patient also showed classical acanthosis nigricans in the axillae and groin. The soles were spared. Histopathologic findings in palmar lesions consisted of an undulant epidermis, with hyperkeratosis, acanthosis, and pa

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16

Hopkins, Katherine, Åsa Ingvar, Johan Palmgren, Valdis Thorhallsdottir, Kari Nielsen, and Karim Saleh. "Histopathological Diagnostic Discordance between Punch Biopsies and Final Diagnostic Excisions of Cutaneous Squamous Cell Carcinoma: Analysis of 737 Cases." Acta Dermato-Venereologica 105 (January 3, 2025): adv40727. https://doi.org/10.2340/actadv.v105.40727.

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The recommended treatment for cutaneous squamous cell carcinoma is surgical excision. An initial punch biopsy is often performed as an aid to diagnosis. A retrospective registry-based study was performed to assess histopathological concordance of punch biopsy of cutaneous squamous cell carcinoma and subsequent excision. Analysis of 737 punch biopsies and subsequent matched excisions was performed. In total, 493 (67%) lesions were confirmed as invasive cutaneous squamous cell carcinoma on excision, 76% when excluding “scar” as a final diagnosis. Tumour diameter > 20mm was highly predictive o

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17

Kumar, S. V., and Rohit Mula. "Papillary Thyroid Carcinoma Presenting as Fungating Cutaneous Mass." Asian Pacific Journal of Health Sciences 5, no. 4 (2018): 113–15. http://dx.doi.org/10.21276/apjhs.2018.5.4.17.

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18

Fukuda, Risa, Usuda Shin, Asoda Seiji, and Funakoshi Takeru. "A case of primary cutaneous adenoid cystic carcinoma." Journal of the Japan Organization of Clinical Dermatologists 33, no. 3 (2016): 389–93. http://dx.doi.org/10.3812/jocd.33.389.

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19

Ninan, Jiby Soosen, Ajithakumari K., and Tony Mathew. "Primary Cutaneous Mucinous Carcinoma Presenting as an Unusually Large Lesion - A Rare Case Report." Journal of Evolution of Medical and Dental Sciences 10, no. 34 (2021): 2939–41. http://dx.doi.org/10.14260/jemds/2021/599.

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Primary cutaneous mucinous carcinoma (PCMC) also known as primary mucinous carcinoma of the skin (PMCS) or primary mucinous eccrine carcinoma (PMEC) is a rare malignant adnexal tumour of eccrine origin. Many visceral mucinous carcinomas especially of the breast and gastrointestinal tract can metastasize to the skin mimicking PCMC. Hence it is very important to rule out metastatic mucinous carcinomas before making a diagnosis of PCMC. Usually, PCMC presents as a slowgrowing tumour of considerably smaller size compared to our case. The large size and shorter duration are the key features of this

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20

Niu, Dongfeng, Yanhua Bai, Qian Yao, et al. "Expression and Significance of AQP3 in Cutaneous Lesions." Analytical Cellular Pathology 2021 (October 26, 2021): 1–6. http://dx.doi.org/10.1155/2021/7866471.

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Aquaporin 3 (AQP3) is the membrane channel of water and involved in fluid homeostasis. The aim of this study was to reveal the expression and significance of AQP3 in cutaneous lesions. We analyzed AQP3 mRNA levels using RT-PCR in 311 cutaneous lesions and confirmed AQP3 expression in these lesions by immunohistochemistry. AQP3 mRNA was detected in normal epidermis, seborrheic keratosis, solar keratosis, Bowen’s disease, squamous cell carcinoma, eccrine poroma, apocrine carcinoma, and sebaceoma; however, AQP3 mRNA was absent in basal cell carcinoma, nevocellular nevus, or malignant melanoma. By

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21

Jiang, Yannan, Runqiu Liu, Xinghui Li, and Yunjiang Wang. "Ubiquitin-Conjugating Enzyme E2C Activates Phosphatidylinositol 3-Kinase/Protein Kinase B Pathway to Promote Growth and Migration of Cutaneous Squamous Cell Carcinoma Cells." Current Topics in Nutraceutical Research 22, no. 2 (2024): 544–51. http://dx.doi.org/10.37290/ctnr2641-452x.22:544-551.

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Cutaneous squamous cell carcinoma is prone to metastasis at its advanced stage. Previous studies reported that the ubiquitin-conjugating enzyme E2C is a proto-oncogene that causes cancer in various tumors. This study aimed to investigate the role of the ubiquitin-conjugating enzyme E2C in cutaneous squamous cell carcinoma. We initially analyzed the expression profile in the gene expression omnibus database. We obtained the intersection genes, established a protein-protein interaction network, and identified ubiquitin-conjugating enzyme E2C as the key gene. Furthermore, microarray data revealed

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22

Kramb, Felix, Christoph Doerfer, Andreas Meiwes, et al. "Real-world Treatment Patterns and Outcomes with Systemic Therapies in Unresectable Locally Advanced and Metastatic Cutaneous Squamous Cell Carcinoma in Germany." Acta Dermato-Venereologica 102 (January 26, 2022): adv00637. http://dx.doi.org/10.2340/actadv.v101.751.

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Advanced cutaneous squamous cell carcinoma is a challenge to treat. Conventional systemic treatment options include chemotherapy and epidermal growth factor receptor-inhibitors. The aim of this study was to assess clinical outcomes with systemic treatments in advanced cutaneous squamous cell carcinoma. Patients receiving systemic treatment at the Tübingen Dermato-Oncology centre between 2007 and 2017 were identified (n = 59). Median age was 76 years (interquartile range (IQR) 71–80 years), 83.1% of patients were male, 72.9% had metastatic cutaneous squamous cell carcinoma, and 27.1% had unrese

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23

Poonia, Usha, Jagat Singh, Manisha Kumari, and Sukriti Bansal. "Unusual presentation of lung carcinoma as nasal tip metastasis: A review of literature." IP Journal of Otorhinolaryngology and Allied Science 4, no. 3 (2021): 122–26. http://dx.doi.org/10.18231/j.ijoas.2021.024.

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Lung carcinoma is the most common type of carcinoma seen in males and 4 most common in females. Skin metastasis from lung carcinoma is frequent with an incidence of 1%-12%, with most common site being the anterior chest wall. Skin metastasis from lung carcinoma to the tip of nose is very rare with only 12 cases being reported in literature(Table 1). It can be confused with other benign and malignant conditions, such as infection, lymphoma, hemangioma, rhinophyma, sarcoidosis, tuberculosis and carcinomas, making its diagnosis difficult. Less than 20 cases of cutaneous nasal tip metastasis are r

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24

Dantal, Jacques, Emmanuel Morelon, Lionel Rostaing, et al. "Sirolimus for Secondary Prevention of Skin Cancer in Kidney Transplant Recipients: 5-Year Results." Journal of Clinical Oncology 36, no. 25 (2018): 2612–20. http://dx.doi.org/10.1200/jco.2017.76.6691.

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Purpose Transplant recipients who develop cutaneous squamous cell carcinomas are at high risk for multiple subsequent skin cancers. Sirolimus has been shown to reduce the occurrence of secondary skin cancers, but no study included a follow-up exceeding 2 years. We extended at 5 years the TUMORAPA randomized trial of sirolimus-based immunosuppressive regimen versus calcineurin inhibitor–based immunosuppression. Methods Kidney transplant recipients receiving calcineurin inhibitors who had at least one cutaneous squamous cell carcinoma were randomly assigned to receive sirolimus as a substitute f

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Caceres, Paola, Franklin Cabrera, Verónica Posso, et al. "Trichilemmal Carcinoma: A Diagnostic Challenge Case Report." Journal of Dermatology and Clinical Research 12, no. 1 (2024): 1–2. http://dx.doi.org/10.47739/dermatology.1159.

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Trichilemmal carcinoma is a rare cutaneous tumor, representing only 1% of all adnexal carcinomas. It derives from the outer root sheath of the hair follicle. Clinically, it manifests as a skin-colored or slightly pink papule in sun-exposed areas in elderly patients. The following is a case report detailing trichilemmal carcinoma arising from a previous lesion and its correlation with histopathology

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26

Ene, Corina Daniela, Ilinca Nicolae, Mircea Tampa, et al. "The Cellular Stress and Cutaneous Manifestations in Renal Cell Carcinomas—A Narrative Review." Journal of Clinical Medicine 13, no. 13 (2024): 3640. http://dx.doi.org/10.3390/jcm13133640.

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The carcinomas originating from the renal cortex are the most aggressive renal malignancies, with a high tendency for metastasis. Understanding the incidence of cutaneous manifestations caused by renal carcinomas is a challenge. In the first part, this article summarizes a series of factors that promote oncogenesis, invasiveness, and the ability of renal cell carcinoma (RCC) to develop secondary cutaneous manifestations. It is postulated that the cellular stress response is one of the leading causes of developing dermatological events induced by cancers located at distant sites. Furthermore, t

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27

SungYul, Lee, Lee JiHye, Oh SangJin, Lee HanEul, and Lee JongSuk. "Primary cutaneous sarcomatoid carcinoma." Indian Journal of Dermatology, Venereology, and Leprology 78, no. 5 (2012): 665. http://dx.doi.org/10.4103/0378-6323.100536.

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28

Alam, Murad, and Désirée Ratner. "Cutaneous Squamous-Cell Carcinoma." New England Journal of Medicine 344, no. 13 (2001): 975–83. http://dx.doi.org/10.1056/nejm200103293441306.

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29

Robson, Alistair, Alexander J. F. Lazar, Jara Ben Nagi, et al. "Primary Cutaneous Apocrine Carcinoma." American Journal of Surgical Pathology 32, no. 5 (2008): 682–90. http://dx.doi.org/10.1097/pas.0b013e3181590ba4.

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30

Gartrell, Richard, John Pauli, and Mark Zonta. "Primary Cutaneous Mucoepidermoid Carcinoma." International Journal of Surgical Pathology 23, no. 2 (2014): 161–64. http://dx.doi.org/10.1177/1066896914554834.

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31

Motaparthi, Kiran, Jyoti P. Kapil, and Elsa F. Velazquez. "Cutaneous Squamous Cell Carcinoma." Advances In Anatomic Pathology 24, no. 4 (2017): 171–94. http://dx.doi.org/10.1097/pap.0000000000000157.

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32

López, Verónica, Miguel Rubio, Nuria Santonja, and Esperanza Jordá. "Primary Cutaneous Mucoepidermoid Carcinoma." American Journal of Dermatopathology 32, no. 6 (2010): 618–20. http://dx.doi.org/10.1097/dad.0b013e3181cdad06.

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33

Garcia-Zuazaga, Jorge, and Suzanne M. Olbricht. "Cutaneous Squamous Cell Carcinoma." Advances in Dermatology 24 (November 2008): 33–57. http://dx.doi.org/10.1016/j.yadr.2008.09.007.

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34

Parekh, Vishwas, and John T. Seykora. "Cutaneous Squamous Cell Carcinoma." Clinics in Laboratory Medicine 37, no. 3 (2017): 503–25. http://dx.doi.org/10.1016/j.cll.2017.06.003.

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35

Seidl-Philipp, Magdalena, and Van Anh Nguyen. "Cutaneous squamous cell carcinoma." memo - Magazine of European Medical Oncology 13, no. 1 (2020): 106–10. http://dx.doi.org/10.1007/s12254-019-00554-3.

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SummaryCutaneous squamous cell carcinoma (cSCC) accounts for approximately 20% of all skin cancers. Its rising incidence represents a major public health concern. The majority of cSCC are curable by surgical resection. Although less than 5% of cSCC patients develop metastases or local recurrence after complete excision, advanced cSCC is difficult to treat. Until recently, no standard therapeutic regimen for advanced cSCC exists. Traditional therapies include chemotherapy and EGFR-targeted therapy, but their clinical benefit remains modest and has been demonstrated mostly in retrospective studi

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36

Vandeweyer, E., J. L. Dargent, and R. Deraemaecker. "Lethal Cutaneous Verrucous Carcinoma." Acta Chirurgica Belgica 102, no. 2 (2002): 134–36. http://dx.doi.org/10.1080/00015458.2002.11679282.

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37

Ruiz, Sory J., Suhair Al Salihi, Victor G. Prieto, et al. "Unusual cutaneous metastatic carcinoma." Annals of Diagnostic Pathology 43 (December 2019): 151399. http://dx.doi.org/10.1016/j.anndiagpath.2019.08.003.

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Mendenhall, William M., Jessica M. Kirwan, Christopher G. Morris, Robert J. Amdur, John W. Werning, and Nancy P. Mendenhall. "Cutaneous Merkel cell carcinoma." American Journal of Otolaryngology 33, no. 1 (2012): 88–92. http://dx.doi.org/10.1016/j.amjoto.2011.02.003.

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Loh, Seung-Hee, Yu-Jin Oh, Bark-Lynn Lew, and Woo-Young Sim. "Primary Cutaneous Apocrine Carcinoma." Annals of Dermatology 28, no. 5 (2016): 669. http://dx.doi.org/10.5021/ad.2016.28.5.669.

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Waldman, Abigail, and Chrysalyne Schmults. "Cutaneous Squamous Cell Carcinoma." Hematology/Oncology Clinics of North America 33, no. 1 (2019): 1–12. http://dx.doi.org/10.1016/j.hoc.2018.08.001.

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Kamalpour, Loebat, Renata T. Brindise, Michael Nodzenski, Daniel Q. Bach, Emir Veledar, and Murad Alam. "Primary Cutaneous Mucinous Carcinoma." JAMA Dermatology 150, no. 4 (2014): 380. http://dx.doi.org/10.1001/jamadermatol.2013.6006.

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Que, Syril Keena T., Fiona O. Zwald, and Chrysalyne D. Schmults. "Cutaneous squamous cell carcinoma." Journal of the American Academy of Dermatology 78, no. 2 (2018): 249–61. http://dx.doi.org/10.1016/j.jaad.2017.08.058.

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Que, Syril Keena T., Fiona O. Zwald, and Chrysalyne D. Schmults. "Cutaneous squamous cell carcinoma." Journal of the American Academy of Dermatology 78, no. 2 (2018): 237–47. http://dx.doi.org/10.1016/j.jaad.2017.08.059.

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Bander, Thomas S., Kishwer S. Nehal, and Erica H. Lee. "Cutaneous Squamous Cell Carcinoma." Dermatologic Clinics 37, no. 3 (2019): 241–51. http://dx.doi.org/10.1016/j.det.2019.03.009.

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45

Schembri-Wismayer, David, Sounak Gupta, and Lori A. Erickson. "Cutaneous Adenoid Cystic Carcinoma." Mayo Clinic Proceedings 99, no. 6 (2024): 1017–18. http://dx.doi.org/10.1016/j.mayocp.2024.02.029.

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46

Xia, Chen, Zhigang Chu, Dongmei Jin, Yan Xiao, Wen Ma, and Maojie Cheng. "Sinomenine Suppresses Cell Progression and Induces Cell Apoptosis by Regulating AKT/mTOR Signaling Pathway in Cutaneous Squamous Cell Carcinoma Cells." Current Topics in Nutraceutical Research 20, no. 2 (2021): 393–99. http://dx.doi.org/10.37290/ctnr2641-452x.20:393-399.

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While sinomenine plays a crucial anticancer role in a variety of cancers, its function and molecular mechanism in cutaneous squamous cell carcinoma remains unexplored. To this end, we explored the effect of sinomenine on cell viability, colony formation rate, cell apoptosis rate, and migration and invasion and wound healing in A431 and SCL-1 cells representing cutaneous squamous cell carcinoma. The results show that sinomenine inhibited cutaneous squamous cell carcinoma viability, clone formation, migration and invasion, induced cell apoptosis by inactivating AKT/mTOR pathway. These data may l

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47

Xu, Yaohui G., Molly Hinshaw, B. Jack Longley, Humza Ilyas, and Stephen N. Snow. "Cutaneous Adenoid Cystic Carcinoma with Perineural Invasion Treated by Mohs Micrographic Surgery—A Case Report with Literature Review." Journal of Oncology 2010 (2010): 1–5. http://dx.doi.org/10.1155/2010/469049.

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We report a 58-year-old woman with cutaneous adenoid cystic carcinoma arising on the chest treated with Mohs micrographic surgery. The patient remained tumor-free at 24-month follow-up. To date, only six other cases of cutaneous adenoid cystic carcinoma were reportedly managed by Mohs surgery. Cutaneous adenoid cystic carcinoma has low potential for distant metastasis but is notorious for its aggressive infiltrative growth pattern, frequent perineural invasion, and high risk of local recurrence after excision. We propose that Mohs surgery is an ideal method to achieve margin-free removal of cu

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48

Tele, Jyoti, S. R. Kanetkar, and S. S. Kumbhar. "Solitary Cutaneous Metastasis of Carcinoma Larynx - An Unusual Occurrence." International Journal of Health Sciences and Research 12, no. 2 (2022): 194–98. http://dx.doi.org/10.52403/ijhsr.20220227.

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Background - Carcinoma larynx with cutaneous metastasis is rare to occur. Cutaneous metastasis from head and neck region are usually considered a poor prognostic sign. Case Report - We report a case of moderately differentiated carcinoma of larynx presenting with solitary cutaneous metastasis in suprascapular region. Patient is a 40 year old lady, farmer by occupation who developed dysphagia and throat pain for which she was investigated and on biopsy was diagnosed as moderately differentiated squamous cell carcinoma of larynx. When she was admitted for chemoradiotherapy, a swelling was noted

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Soni, Monica, Sudesh Aggarwal, Prasoon Soni, Puja Gupta, Shaifali Dadhich, and Sharadlata Saini. "Vulvar Merkel Cell Carcinoma: A Rare Entity." Journal of South Asian Federation of Obstetrics and Gynaecology 3, no. 3 (2011): 145–46. http://dx.doi.org/10.5005/jp-journals-10006-1153.

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ABSTRACT Merkel cell carcinoma is a primary small cell carcinoma of the skin that resembles oat cell carcinomas of the lung. This tumor has a predilection for head and neck region but may rarely occur as isolated vulvar tumor. It has aggressive malignant behavior and should not be missed while evaluating vulvar masses. We report a case of 45-year-old Mrs I, who presented with recurrent vulvar swelling and was diagnosed as stage III Merkel cell carcinoma of the vulva. Synonyms Primary neuroendocrine carcinoma, Trabecular carcinoma, Primary small cell carcinoma, Cutaneous apudoma.

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Kanchan, Chaudhary, Kumar Verma Jyoti, Kumar Pandey Ranbir, and Kumar Chaudhary Mihir. "Unusal Presentation of Lung Carcinoma as Nasal Tip metastasis: A Review of Literature." International Journal of Pharmaceutical and Clinical Research 16, no. 5 (2024): 2469–74. https://doi.org/10.5281/zenodo.13336678.

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Abstract:

Lung carcinoma is the most common type of carcinoma seen in males and 4<sup>th</sup> most common in females. (1) Skin metastasis from lung carcinoma is frequent with an incidence of 1%-12%, with most common site being the anterior chest wall. (2) Skin metastasis from lung carcinoma to the tip of nose is very rare with only 12 cases being reported in literature (Table 1). It can be confused with other benign and malignant conditions, such as infection, lymphoma, hemangioma, rhinophyma, sarcoidosis, tuberculosis and carcinomas, making its diagnosis difficult. (3) Less than 20 cases of cutan

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