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1

K., Ganesan S. Kaveriammal and S. Sridhar*. "AN IN-VITRO STUDY ON ANTI-INFLAMMATORY AND ANTI-BACTERIAL ACTIVITIES OF ETHYL ACETATE EXTRACT FROM THE LEAVES OF CYCLEA PELTATA." Indo American Journal of Pharmaceutical Sciences 04, no. 12 (2017): 4334–42. https://doi.org/10.5281/zenodo.1098076.

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The present study was to evaluate the anti-inflammatory activity and their inhibitions way were investigated by Ethyl acetate extract of Cyclea peltata. Initially the phytochemical analysis was performed to identify the bioactive compounds responsible for the inflammatory activity. These plant possessed alkaloid, flavonoid, terpenoid and polyphenols, glycosides. Among the phytochemicals identified flavonoid extract found to have higher antiinflammatory activity against inflammatory enzymes like cycloxygenase and lipoxygenase. The strategies of in-vitro cycloxygenase and lipoxygenase inhibitory
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Poonghuzhali, R., Sujith Samraj, A. R. Nisha, Suresh N. Nair, and MN Priya. "Phytopharmacological characterization of different extracts and fractions of Cyclea peltata." Journal of Phytopharmacology 11, no. 3 (2022): 155–58. http://dx.doi.org/10.31254/phyto.2022.11304.

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Cyclea peltata is a shrub belongs to Menispermiaceae family and is commonly known as “Pedal” or “Pada thalli”. The plant has been used since ancient times in traditional medicine as a healing herb for the treatment of various ailments such as skin infections, wounds, antipyretic, diuretic, diabetes, asthma, jaundice and snakebite poisoning. The objective of the present study was to characterize the active phytochemical constituents present in the aqueous, methanolic and n-hexane, dichloromethane, nbutanol, water fractions of methanolic extracts of C. peltata. To analyse the potent bioactive co
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Fathima, Nuha Mohamed Ubaidullah, and T.Mahendran. "Extraction of Leaf gel from Cyclea peltata and Its Utilization in Ice cream Manufacture." International Journal of Environmental and Agriculture Research 11, no. 2 (2025): 53–56. https://doi.org/10.5281/zenodo.14936532.

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Ice cream is a frozen dessert that consists of ice crystals, air cells, fat globules, and liquid syrup. Stabilizers are added to reduce meltdown, increase viscosity, and add smoothness to the ice cream. Gelatin is an important stabilizer used in ice cream manufacture, which is produced from animal origin. Thus, consumers of lacto-vegetarian are highly affected. This study was conducted to find out the most suitable grams of leaf gel from the Cyclea peltata plant to produce a gelatin substitute and investigate the physico-chemical properties and storage of ice cream incorporated with Cyclea pel
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4

Ramakrishna S, Ujaneshwar Mayachari, Narayana Murthy G, and Likhitha K. "Phytochemical Profiling and Evaluation of Anthelmintic Activity of Cyclea peltata Leaf Extract." Journal of Pharma Insights and Research 3, no. 2 (2025): 098–104. https://doi.org/10.69613/hs26ry81.

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Cyclea peltata (Lam.) Hook.f. & Thomson, traditionally known as "Haade balli" in Karnataka, India, has been an integral component of indigenous medicine systems for treating various ailments, including parasitic infections. This study investigated the phytochemical constituents and anthelmintic potential of C. peltata leaf extract. The aqueous extract was prepared using reflux extraction method, yielding 28% w/w of dark brownish-black extract. Phytochemical screening revealed the presence of alkaloids, carbohydrates, saponins, flavonoids, tannins, phenolic compounds, resins, and terpenoids
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Roshni, SS, Sneha Geevarghese, S. Sujith, Preethy John, R. Uma, and AR Nisha. "Evaluation of cytotoxic potential of leaves of Cyclea peltata in MCF-7 cell lines." Journal of Phytopharmacology 14, no. 2 (2025): 78–86. https://doi.org/10.31254/phyto.2025.14202.

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It is a well-established fact that breast cancer causes severe mortality among women globally. The invention of a vast number of medications currently used in the treatment of cancer was made possible from studies on natural products. Cyclea peltata is a locally available medicinal plant which has been used for the treatment of various diseases including diabetes. The present study reports the antiproliferative and cytotoxic action of alcoholic extract and its fractions of the leaves of C. peltata in MCF-7 cell lines. The extract of C. peltata and its fractions were subjected to qualitative ph
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Rajkumar S, Sambathkumar R, Gomathi Swaminathan, Vijayabaskaran M, and Kannan C. "Evaluation of Fluoride-Induced Neuro Degenerative Defences in Cyclea Peltata Lam Roots." International Journal of Research in Pharmaceutical Sciences 11, no. 4 (2020): 8034–41. http://dx.doi.org/10.26452/ijrps.v11i4.4756.

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Many diseases have become easier to diagnose and treat as a result of advancements in medical science and technology, but strokes, which have multiple etiologies and mechanisms, continue to be difficult to treat. Synthetic drugs are notorious for causing a slew of unavoidable side effects. Herbal drugs have a wide range of mechanisms of action and are typically free of side effects, making them excellent alternatives to synthetic drugs for stroke treatment. Cyclea peltata (Lam) Hook f. Thoms roots were studied for their neuroprotective properties against fluoride-induced neurodegeneration in r
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7

Chellappan, David Raj, Jipnomon Joseph, and Parimaladevi Balasubramanian. "Pharmacognostical, antioxidant and antiulcer screening of Cyclea peltata roots." Revista Brasileira de Farmacognosia 21, no. 6 (2011): 1096–103. http://dx.doi.org/10.1590/s0102-695x2011005000168.

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8

Hullatti, KK, UV Gopikrishna, and IJ Kuppast. "Phytochemical investigation and diuretic activity of Cyclea peltata leaf extracts." Journal of Advanced Pharmaceutical Technology & Research 2, no. 4 (2011): 241. http://dx.doi.org/10.4103/2231-4040.90880.

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9

Meena, J., and K. S. Santhy. "ANTICANCER EFFICACY OF CYCLEA PELTATA ON HUMAN BREAST CARCINOMA CELLS." INDIAN DRUGS 54, no. 06 (2017): 53–57. http://dx.doi.org/10.53879/id.54.06.10783.

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Cancer has now been designated as a preventable disease with the increasing interest by the research community. The impartial administration of chemical treatments has now shifted to natural products due to the side effects observed with chemotherapy. In the present study, a pharmaceutical approach is undertaken to screen the anticancer potential of Cyclea peltata against breast cancer. We examined the in vitro anticancer potential of MCF-7 cancer cell lines by MTT assay using various concentrations of the methanol extract of the plant. In silico analysis were carried out by Schrodinger suite.
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10

Sukanya, BCV, and PR Bhat. "Phytochemical, antimicrobial, antioxidant and immunomodulatory studies of leaf extracts of Cyclea peltata (Lam.) Hook. f. & Thomson." GSC Biological and Pharmaceutical Sciences 9, no. 3 (2019): 052–63. https://doi.org/10.5281/zenodo.4283213.

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The objective of the present investigation is to study the phytochemical constituents, antimicrobial, antioxidant activity and immunomodulatory effects of&nbsp;<em>Cyclea peltata&nbsp;</em>leaf extract. The fresh whole plants were collected from Kannur, Kerala, India. The crude extract of leaves of&nbsp;<em>C. peltata&nbsp;</em>prepared using methanol and aqueous solvents and were used to investigate the antibacterial activity against&nbsp;<em>Streptococcus mutans</em>,&nbsp;<em>Staphylococcus aureus, Escherichia coli, Pseudomonas aeruginosa&nbsp;</em>and&nbsp;<em>Klebsiella pneumoniae&nbsp;</
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11

S., Jagadeep Chandra, Mahadeva Murthy S., and Ranjana Ramesh. "EVALUATION OF THE WOUND HEALING ACTIVITY OF CAESALPINIA BONDUCELLA AND CYCLEA PELTATA EXTRACTS IN EXPERIMENTALLY INDUCED DIABETIC RATS." International Journal of Pharmacy and Pharmaceutical Sciences 9, no. 10 (2017): 211. http://dx.doi.org/10.22159/ijpps.2017v9i10.19788.

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Objective: The present study was conducted to verify the effect of Caesalpinia bonducella and Cyclea peltata extracts on experimentally induced excision wounds in diabetic rats.Methods: Methanolic and ethyl acetate extract of test sample in PEG base was applied and observed for wound healing effect for a period of 15 d.Results: The data demonstrated statistically significant wound contraction up to 98% in the treated sample as compared to 90% in diabetic control group. The results correlated (r ³ 0.95) with fasting blood glucose level, indicating the deleterious effect of hyperglycemia in woun
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12

Abraham, Jyothi, and T. Dennis Thomas. "Antibacterial activity of medicinal plant Cyclea peltata (Lam) Hooks & Thoms." Asian Pacific Journal of Tropical Disease 2 (January 2012): S280—S284. http://dx.doi.org/10.1016/s2222-1808(12)60166-2.

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13

Narasimhan, S. "Ultrastructural and histochemical analysis of the trichomes of Cyclea peltata (Menispermaceae)." Medicinal Plants - International Journal of Phytomedicines and Related Industries 11, no. 4 (2019): 422. http://dx.doi.org/10.5958/0975-6892.2019.00055.8.

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14

Sivaraman, Thulasi, N. S. Sreedevi, and S. Meenatchisundaram. "Identification and Quantification of antivenom compounds from aqueous extract of Cyclea peltata root." Research Journal of Pharmacy and Technology 11, no. 4 (2018): 1386. http://dx.doi.org/10.5958/0974-360x.2018.00259.7.

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15

N, Pavithra, Ravi Krishna S, Ranjana K, and Chaitra Hebbar. "A COMPREHENSIVE REVIEW ON ETHNOMEDICAL STUDY AND PHARMACOLOGICAL ACTIVITY OF RAJAPATA (CYCLEA PELTATA)." International Journal of Research in Ayurveda and Pharmacy 15, no. 6 (2024): 72–75. https://doi.org/10.7897/2277-4343.156195.

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Dravya (Drug) is one among the chikitsa chatushpada (4 important treatment protocols). It is equally important for a physician to choose the right drug depending on the disease condition. In Ayurveda there is reference of n number of drugs, our Acharyas have given detailed description about it in various Ayurvedic classics, and there are millions of drugs yet to be discovered. Among the drugs which are presently available there is a need for discovery of its pharmacological action. Many researchers are being conducted and proved the effect, chemical constituents, mode of action, pharmacologica
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16

Sivaraman, Thulasi, NS Sreedevi, S. Meenatchisundaram, and R. Vadivelan. "Antitoxin activity of aqueous extract of Cyclea peltata root against Naja naja venom." Indian Journal of Pharmacology 49, no. 4 (2017): 275. http://dx.doi.org/10.4103/ijp.ijp_708_16.

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17

Snesha, S.R, and Arthi I. Dr. "Research on Synergestic Anthelmintic Activity of Methanolic Extract of the Leaves of Cyclea Peltata Lam and Roots of Cocos Nucifera Linn Against Adult Pheretima Posthuma Worms and it's Statistical Analysis." International Journal Of Ayurvedic And Herbal Medicine 14, no. 05 (2024): 4465–73. https://doi.org/10.5281/zenodo.13683770.

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<strong>ABSTRACT :&nbsp;</strong> The&nbsp; aim of the&nbsp; research is to develop a safe and effective anthelmintic from plants, due to the increasing toxic effect of synthetic drugs. The reason behind this research is the undesirable side effects of synthetic drugs available in the market like drug resistance. So there is a need for the exploration of more medicinal plants for the treatment of various worm infections. Here the anthelmintic activity of combined methanolic extract of leaves of Cyclea peltata and roots of Cocos nucifera were studied. The extract were prepared by maceration tec
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18

Suvarna, Asha R., Anvitha Shetty, Sneha Anchan, Nasreena Kabeer, and Sneha Nayak. "Cyclea peltata Leaf Mediated Green Synthesized Bimetallic Nanoparticles Exhibits Methyl Green Dye Degradation Capability." BioNanoScience 10, no. 3 (2020): 606–17. http://dx.doi.org/10.1007/s12668-020-00739-9.

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19

Shine, V. J., P. G. Latha, S. Shyamal, et al. "Gastric antisecretory and antiulcer activities of Cyclea peltata (Lam.) Hook. f. & Thoms. in rats." Journal of Ethnopharmacology 125, no. 2 (2009): 350–55. http://dx.doi.org/10.1016/j.jep.2009.04.039.

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20

Nayak, Sneha, K. B. Manjunatha, Louella Concepta Goveas, C. Vaman Rao, and Shyama Prasad Sajankila. "Investigation of Nonlinear Optical Properties of AgNPs Synthesized Using Cyclea peltata Leaf Extract Post OVAT Optimization." BioNanoScience 11, no. 3 (2021): 884–92. http://dx.doi.org/10.1007/s12668-021-00875-w.

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21

Christina, A. J. M., M. Packia Lakshmi, M. Nagarajan, and S. Kurian. "Modulatory effect of Cyclea peltata Lam. on stone formation induced by ethylene glucol treatment in rats." Methods and Findings in Experimental and Clinical Pharmacology 24, no. 2 (2002): 77. http://dx.doi.org/10.1358/mf.2002.24.2.677130.

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22

Sukanya BCV and Bhat PR. "Phytochemical, antimicrobial, antioxidant and immunomodulatory studies of leaf extracts of Cyclea peltata (Lam.) Hook. f. & Thomson." GSC Biological and Pharmaceutical Sciences 9, no. 3 (2019): 052–63. http://dx.doi.org/10.30574/gscbps.2019.9.3.0228.

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23

Singh, SumanG, K. Nishteswar, BhupeshR Patel, and Mukesh Nariya. "Comparative antipyretic and analgesic activities of Cissampelos pareira Linn. and Cyclea peltata (Lam.)Hook. F. & Thomas." AYU (An international quarterly journal of research in Ayurveda) 37, no. 1 (2016): 62. http://dx.doi.org/10.4103/ayu.ayu_208_14.

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24

N., Bhagya, K. R. Chandrashekar, Ashwini Prabhu, and P. D. Rekha. "Tetrandrine isolated from Cyclea peltata induces cytotoxicity and apoptosis through ROS and caspase pathways in breast and pancreatic cancer cells." In Vitro Cellular & Developmental Biology - Animal 55, no. 5 (2019): 331–40. http://dx.doi.org/10.1007/s11626-019-00332-9.

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25

Shine, V. J., G. I. Anuja, S. R. Suja, Gopan Raj, and P. G. Latha. "Bioassay guided fractionation of Cyclea peltata using in vitro RAW 264.7 cell culture, antioxidant assays and isolation of bioactive compound tetrandrine." Journal of Ayurveda and Integrative Medicine 11, no. 3 (2020): 281–86. http://dx.doi.org/10.1016/j.jaim.2018.05.009.

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26

Pullaiah, T., and E. Chennaiah. "Cyclea peltata (Lam.) Hook. F. and Thoms., Viola betonicifolia J.E. Smith and Tephrosia candida (Roxb.) DC: New records for Andhra Pradesh." Journal of the Bombay Natural History Society 88 (June 12, 1991): 464–65. https://doi.org/10.5281/zenodo.13436063.

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Pullaiah, T., and E. Chennaiah. "Cyclea peltata (Lam.) Hook. F. and Thoms., Viola betonicifolia J.E. Smith and Tephrosia candida (Roxb.) DC: New records for Andhra Pradesh." Journal of the Bombay Natural History Society 88 (June 7, 1991): 464–65. https://doi.org/10.5281/zenodo.13436063.

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Pullaiah, T., and E. Chennaiah. "Cyclea peltata (Lam.) Hook. F. and Thoms., Viola betonicifolia J.E. Smith and Tephrosia candida (Roxb.) DC: New records for Andhra Pradesh." Journal of the Bombay Natural History Society 88 (July 3, 1991): 464–65. https://doi.org/10.5281/zenodo.13436063.

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Pullaiah, T., and E. Chennaiah. "Cyclea peltata (Lam.) Hook. F. and Thoms., Viola betonicifolia J.E. Smith and Tephrosia candida (Roxb.) DC: New records for Andhra Pradesh." Journal of the Bombay Natural History Society 88 (July 10, 1991): 464–65. https://doi.org/10.5281/zenodo.13436063.

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Pullaiah, T., and E. Chennaiah. "Cyclea peltata (Lam.) Hook. F. and Thoms., Viola betonicifolia J.E. Smith and Tephrosia candida (Roxb.) DC: New records for Andhra Pradesh." Journal of the Bombay Natural History Society 88 (July 17, 1991): 464–65. https://doi.org/10.5281/zenodo.13436063.

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31

K.P, Prasanth, and Sekaran S. "A COMPARATIVE ANATOMICAL CHARACTERISTICS OF THE STEMS OF CLIMBING PLANTS IN ARALAM WILD LIFE SANCTUARY, KANNUR." Kongunadu Research Journal 3, no. 1 (2016): 37–44. http://dx.doi.org/10.26524/krj124.

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Climbing plants differ from self-supporting plants, such as shrubs and trees, in a range of characteristics. The most notable is the mechanical properties of the stem Comparison of the differentiated anatomical structures recorded in ten species of the climbing plants. The plants selected for the present study are Ampelocissus latifolia, (Vitaceae), Lygodium flexuosum (Lygodiaceae), Centrosema virginianum (Fabaceae), Tinospora cordifolia, (Menispermaceae), Wattakakka volubilis (Asclepiadaceae) Cyclea peltata (Menispermaceae), Calycopteris floribunda (Combretaceae) Pothos scandens (Araceae) Ipo
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K.P, Prasanth, and Sekaran S. "A COMPARATIVE ANATOMICAL CHARACTERISTICS OF THE STEMS OF CLIMBING PLANTS IN ARALAM WILD LEFE SANCTUARY, KANNUR." Kongunadu Research Journal 4, no. 1 (2017): 92–95. http://dx.doi.org/10.26524/krj184.

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Climbing plants differ from self-supporting plants, such as shrubs and trees, in a range of characteristics. The most notable is the mechanical properties of the stem Comparison of the differentiated anatomical structures recorded in ten species of the climbing plants. The plants selected for the present study are Ampelocissus latifolia,(Vitaceae), Lygodium flexuosum (Lygodiaceae), Centrosema virginianum(Fabaceae), Tinospora cordifolia,(Menispermaceae), Wattakakka volubilis (Asclepiadaceae) Cyclea peltata (Menispermaceae), Calycopteris floribunda (Combretaceae) Pothos scandens(Araceae) Ipomoea
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Abraham, Jyothi, Meena K. Cheruvathur, Bince Mani, and T. Dennis Thomas. "A rapid in vitro multiplication system for commercial propagation of pharmaceutically important Cyclea peltata (Lam) Hook & Thoms. based on enhanced axillary branching." Industrial Crops and Products 31, no. 1 (2010): 92–98. http://dx.doi.org/10.1016/j.indcrop.2009.09.011.

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N., Bhagya, and Chandrashekar K. R. "Optimization of column chromatography technique for the isolation of tetrandrine from Cyclea peltata and LC-ESI-MS based quantification and validation of the method." Natural Product Research 33, no. 19 (2019): 2873–77. http://dx.doi.org/10.1080/14786419.2018.1503660.

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35

Shine, VJ, GI Anuja, PG Latha, et al. "Evaluation of CYP2D, CYP1A2 and distribution of tetrandrine, fangchinoline in the brain, liver, and kidney of wistar rats after short-term exposure to Cyclea peltata." Pharmacognosy Magazine 17, no. 5 (2021): 77. http://dx.doi.org/10.4103/pm.pm_166_20.

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Shine, Varghese Jancy, Panikamparambil Gopalakrishnan Latha, Somasekharan Nair Rajam Suja, Gangadharan Indira Anuja, Gopan Raj, and Sreedharan Nair Rajasekharan. "Ameliorative effect of alkaloid extract of Cyclea peltata (Poir.) Hook. f. & Thoms. roots (ACP) on APAP/CCl4 induced liver toxicity in Wistar rats and in vitro free radical scavenging property." Asian Pacific Journal of Tropical Biomedicine 4, no. 2 (2014): 143–51. http://dx.doi.org/10.1016/s2221-1691(14)60223-9.

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Nizar, Amjitha, Rathy Ravindran, Jayanthi Palani, T. Nripan, S. D. Asha, and Meera K. Pynadath. "Anticancer Effects of Ethanolic Extracts of Macaranga Peltata Leaves on Human Oral Squamous Carcinoma Cell Lines: An In Vitro Study." Journal of Pharmacy and Bioallied Sciences 16, Suppl 2 (2024): S1833—S1837. http://dx.doi.org/10.4103/jpbs.jpbs_28_24.

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ABSTRACT Cancer is a disease resulting from the disruption of cell cycle regulation, leading to the abnormal and unchecked proliferation of cells. Medicinal plants are rich in various bioactive phytochemicals or nutritional compounds. The aim is to determine the cytotoxic and genotoxic effects of ethanolic extracts of Macaranga peltata leaves on human oral cancer cell lines. The study setting was centre for Research on Molecular and Applied Sciences, Azeezia College of Dental Sciences and Research. The study design is a Comparative In Vitro study. Shade dried leaves of Macaranga peltata were s
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Singh, A., Ashish S., and S. Katekhaye. "Rajpatha Ethno medicine of Controversial Origin." International Journal of Current Pharmaceutical Review and Research 3, no. 4 (2013): 86–90. https://doi.org/10.5281/zenodo.12690977.

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Medicinal plants constitute an effective source of traditional and modern medicine. Adulterations andsubstitutions are common in raw material trade of medicinal plants. Rajpatha is indigenous drug havingcontroversial origin. Other variety, patha is well established as Cissampelos pareira and sometimes rajpatha isused as substitute for patha. Recently concentration of the alkaloid, beeberine has been suggested as criteria foridentification of authentic plant. The article explores descprtion of Cycela peltata and Stephania hernandifolia,which are usually taken as rajpatha.
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Bringmann, Gerhard, Heiko Rischer, Jan Schlauer, et al. "The Tropical Liana Triphyophyllum peltatum (Dioncophyllaceae): Formation of Carnivorous Organs is only a facultative prerequisite for shoot elongation." Carnivorous Plant Newsletter 31, no. 2 (2002): 44–52. http://dx.doi.org/10.55360/cpn312.gb193.

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The complete life cycle of Triphyophyllum peltatum (Dioncophyllaceae) has been observed under greenhouse conditions. Without passing through the carnivorous stage, the plant reached maturity and, after flowering abundantly, developed the unusual seeds. This cultivation success permitted valuable observations on floral and fruit biology of T. peltatum.
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Dr., Roopesh P. T.*1 Anjali P.*2 Aiahwarya Lakshmi T.2 Suhana Muhammed Kunhi2 Jumana Haseen2. "Formulation And Evaluation of Multipurpose Polyherbal Powder Shampoo." International Journal of Pharmaceutical Sciences 2, no. 12 (2024): 529–43. https://doi.org/10.5281/zenodo.14276667.

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Shampoo is a hair care product, that is used for cleaning hair. The aim of the present work was to develop a multipurpose polyherbal powder shampoo. Here the multipurpose means antidandruff action as well as hair dye action. Dandruff is a chronic scalp condition characterized by scaling, itching and redness of the scalp. Hair dye is usually a substance of synthetic or natural origin, which is used to colour the hair as per the desired shade. In this work various plants such as Wrightia tinctoria, Eclipta prostata, Morinda citrifolia, Cyclia peltata, etc were collected, dried, size reduced, wei
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Sulaiman, Endang, Nopriyeni Nopriyeni, Carles Darwin, and Anggi Lusianti. "Diversity Of Liana Plants Available In The Konak Protected Forest Area, Kepahiang District, Kepahiang Regency." JURNAL PEMBELAJARAN DAN BIOLOGI NUKLEUS 8, no. 3 (2022): 820–30. http://dx.doi.org/10.36987/jpbn.v8i3.3170.

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This study aims to determine the diversity of lianas found in the Konak Protection Forest, Kepahiang District, Kepahiang Regency. Penelitian ini menggunakan metode purposive sampling yang dilaksanakan pada bulan Januari-Februari 2022. Pengambilan sampel menggunakan metode plot, dimana petakan plot disusun sepanjang garis transek secara sistematik. This study used a purposive sampling method,which was carried out in January-February 2022. Sampling used the plot method, where plots were arranged systematically along transect lines. The samples obtained were then identified at the Bengkulu Muhamm
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Maqbool, Muhammad, Kent E. Cushman, Rita M. Moraes, and Patrick D. Gerard. "Overcoming Dormancy of Mayapple Rhizome Segments with Low Temperature Exposure." HortScience 39, no. 2 (2004): 307–11. http://dx.doi.org/10.21273/hortsci.39.2.307.

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American mayapple (Podophyllum peltatum L.) is a rhizomatous, herbaceous perennial found in wooded areas of eastern North America and is a source of the pharmaceutical compound podophyllotoxin. This research was conducted to determine the optimum duration of low temperature exposure in overcoming dormancy of fall-harvested rhizome segments for subsequent use as propagules in greenhouse plantings. Two types of rhizome segments were harvested from the wild and used in this study: two-node rhizome segments consisting of a terminal node and its adjacent one-year-old node and one-node rhizome segme
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Ivanova, Diana, Paraskev Nedialkov, Alexander Tashev, et al. "Anticancer Podophyllotoxin Recovery from Juniper Leaves at Atmospheric and High Pressure Using Eco-Friendly Solvents." Plants 12, no. 7 (2023): 1526. http://dx.doi.org/10.3390/plants12071526.

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Podophyllotoxin (PPT) is a precursor for the synthesis of drugs against cancer and other diseases. The present sources of PPT (Sinopodophyllum hexandrum and Podophyllum peltatum) are endangered species, with PPT production highly dependent on their growing conditions. In connection with the identification of new sources of PPT, the present study aimed to recover PPT from Juniperus virginiana leaves via atmospheric or high pressure extraction methods with a focus on using eco-friendly solvents. PPT quantification was determined by UHPLC/HRMS/MS. A thorough study of conventional extraction was c
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Yoon, Goo, Mee-Hyun Lee, Ah-Won Kwak, et al. "Podophyllotoxin Isolated from Podophyllum peltatum Induces G2/M Phase Arrest and Mitochondrial-Mediated Apoptosis in Esophageal Squamous Cell Carcinoma Cells." Forests 11, no. 1 (2019): 8. http://dx.doi.org/10.3390/f11010008.

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Esophageal squamous cell carcinoma (ESCC) is one of the most common cancers in East Asia and is the seventh leading cause of cancer deaths. Podophyllotoxin (PT), a cyclolignan isolated from podophyllum peltatum, exhibits anti-cancer effects at the cellular level. This study investigated the underlying mechanism of anti-cancer effects induced by PT in ESCC cells. Exposure to increasing concentrations of PT led to a significant decrease in the growth and anchorage-independent colony numbers of ESCC cells. PT showed high anticancer efficacy against a panel of four types of ESCC cells, including K
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Opit, George P., Yan Chen, Kimberly A. Williams, James R. Nechols, and David C. Margolies. "Plant Age, Fertilization, and Biological Control Affect Damage Caused by Twospotted Spider Mites on Ivy Geranium: Development of an Action Threshold." Journal of the American Society for Horticultural Science 130, no. 2 (2005): 159–66. http://dx.doi.org/10.21273/jashs.130.2.159.

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In three experiments, damage caused by twospotted spider mite (TSSM; Tetranychus urticae Koch) was correlated with the quality of ivy geranium [Pelargonium peltatum (L.) L'Her ex Aiton], and the action threshold for TSSM on ivy geranium was developed. Ivy geranium quality was measured as overall plant quality—plant size and form, and leaf greenness and glossiness—leaf browning, and leaf distortion. Young plants with high initial TSSM numbers (30 TSSM/plant) exhibited the greatest damage, suggesting that monitoring for TSSM early in the plant production cycle is necessary to prevent extensive d
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N. S., Aswin, Nivedita B.T., Sandeep V. Binorkar, et al. "Metabolite Extraction And Functional Annotation Of Cyclea Peltata From Western Ghats: Insights Into Ethnopharmacological Potential." International Journal of Environmental Sciences, June 18, 2025, 59–66. https://doi.org/10.64252/yre8y403.

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Cyclea peltata is very important medicinal plant which is traditionally used in Vythiri thaluk, Wayanad district, Kerala, India against different diseases in human and animals. The objective of this study was to evaluate antimicrobial activity and characterize the chemical constituents in the extracts of the leaves of Cyclea peltata by using modern techniques like High Performance Liquid Chromatography (HPLC) and Liquid Chromatography–Mass Spectrometry (LC/MS-MS). The evaluation of antimicrobial activity of Cyclea peltata was determined by disc diffusion method. The extracts showed different d
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JAYARAMAN, SONY, and E. JAYADEVI VARIYAR. "IMMUNOMODULATORY, ANTICANCEROUS & ANTIOXIDANTACTIVITIES OF CYCLEA PELTATA (LAM.) HOOK.F. & THOMSON." International Journal of Pharmacy and Pharmaceutical Sciences, October 1, 2019, 40–46. http://dx.doi.org/10.22159/ijpps.2019v11i10.35248.

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Introduction: Cyclea peltata (Lam.) Hook.f. &amp; Thomson is an important plant listed in Ayurveda. The plants are used in digestive, diuretic and inflammatory disorders.&#x0D; Aim: The present study was to study the immunomodulatory, anticancerous and antioxidative properties of the fraction isolated from Cyclea peltata.&#x0D; Methods: The immunomodulatory activity was evaluated in lymphocytes and THP-1 macrophage cell lines. The anticancer activity of the fraction was determined by MTT assay. The antioxidant activity was evaluated by DPPH and total antioxidant assays.&#x0D; Results: The frac
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N, Bhagya, and Chandrashekar KR. "Mass Spectrometry-Based Alkaloid Profiling Of Cyclea Peltata Roots And Evaluation Of In Vitro Cytotoxic Activity." Current Bioactive Compounds 19 (December 1, 2022). http://dx.doi.org/10.2174/1573407219666221201103555.

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Background: Cyclea peltata (Lam.) Hook. f. and Thoms., an ethnomedicinal herb with antitoxin and anti-herpes activities, is used to cure smallpox, wounds, diabetic disorders of the skin, and its use as a cooling agent. In the present study, an attempt has been made to screen different alkaloids present in Cyclea peltata roots using LC-ESI-MS/MS and to evaluate the in vitro cytotoxic activity of alkaloids. Methods: The detection of alkaloids in C. peltata root extract was carried out by performing MRM-based assay using liquid chromatography-mass spectrometry. The cytotoxic effect of the acetone
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Siriwardhana, Pethmi, Sharini C. Somasiri, Maharsha Edirisinghe, and Mahesh Vithanage. "Formulating a gelatine-free set yoghurt with Cyclea peltata." African Journal of Food Science and Technology 09, no. 03 (2018). http://dx.doi.org/10.14303/ajfst.2018.235.

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Singh, Suman, and Nishteswar K. "Review on Cissampelos Pareira and Cyclea Peltata (Patha Dwaya) - Phyto-Pharmacological Perspectives." International Journal of Ayurvedic Medicine 4, no. 4 (2013). http://dx.doi.org/10.47552/ijam.v4i4.288.

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