Academic literature on the topic 'Cyclisation'

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Journal articles on the topic "Cyclisation"

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McBurney, Roy T., and John C. Walton. "Interplay of ortho- with spiro-cyclisation during iminyl radical closures onto arenes and heteroarenes." Beilstein Journal of Organic Chemistry 9 (June 4, 2013): 1083–92. http://dx.doi.org/10.3762/bjoc.9.120.

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Sensitised photolyses of ethoxycarbonyl oximes of aromatic and heteroaromatic ketones yielded iminyl radicals, which were characterised by EPR spectroscopy. Iminyls with suitably placed arene or heteroarene acceptors underwent cyclisations yielding phenanthridine-type products from ortho-additions. For benzofuran and benzothiophene acceptors, spiro-cyclisation predominated at low temperatures, but thermodynamic control ensured ortho-products, benzofuro- or benzothieno-isoquinolines, formed at higher temperatures. Estimates by steady-state kinetic EPR established that iminyl radical cyclisation
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Rodger, Robert T., Marlowe S. Graham, and Christopher S. P. McErlean. "Hyperconjomer stereocontrol of cationic polyene cyclisations." Organic & Biomolecular Chemistry 17, no. 37 (2019): 8551–60. http://dx.doi.org/10.1039/c9ob01364d.

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The stereochemical outcome of cationic polyene cyclisations of geranylbenzene derivatives is affected by the different reactivity of hyperconjomer intermediates. The synthesis of (±)-taiwaniaquinone G by a cationic polyene cyclisation is described.
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Debabrata, Mukherjee. "Total syntheses of sesquiterpenes and diterpenes involving aryl participated cyclisations." Journal of Indian Chemical Society Vol. 77, Nov-Dec 2000 (2000): 553–61. https://doi.org/10.5281/zenodo.5868942.

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Department of Organic Chemistry, Indian Association for the Cultivation of Science, Calcutta-700 032, India <em>E-mail :&nbsp;&nbsp;</em>ocdm@mahendra.iacs.res.in <em>Manuscript received 7 August 2000</em> A brief review is provided of the recent syntheses of sesquiterpenes and diterpenes accomplished in the author&#39;s laborato&shy;ries which serve to underscore the synthetic power of aryl participated cyclisations. The methodology is concerned princi&shy;pally with (a) intramolecular anionic cyclisation of phenols, and (b) acid-induced aryl participated cyclisation of diazomethyl ketones.
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Braddock, D. Christopher, and John M. Brown. "Catalytic and Stoichiometric Lewis Acid Participation in Aldehyde Ene Cyclisations." Collection of Czechoslovak Chemical Communications 65, no. 5 (2000): 741–56. http://dx.doi.org/10.1135/cccc20000741.

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Racemic 2-isopropyl-2-methylhex-5-enal has been synthesised in order to probe ene cyclisations leading to menthol analogues. The objective was first to discover catalytic conditions for preferential cyclisation to the menthol rather than the neomenthol series and then to develop (dynamic) kinetic resolution procedures which afforded a single enantiomer of product. It was found that catalytic quantities of both Me2AlCl and a bulky methylaluminium bis(phenoxide) reagent gave products attributed to a Meerwein-Pondorff-Verley reaction. In this the aldehyde is reduced to a primary alcohol and the e
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Parsons, Philip, Lewis Allen, Daniel Jones, et al. "Approaches to the Synthesis of Highly Substituted Aromatic and Fused Rings: Metal-Catalysed versus Thermal Cyclisation." Synthesis 50, no. 01 (2017): 84–101. http://dx.doi.org/10.1055/s-0036-1590952.

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A domino reaction has been used for the construction of lactonamycin derivatives. This research led to a comparison study between palladium-mediated cascade cyclisations and thermal alkyne [2+2+2] cyclisations. A palladium-mediated cyclisation of alkenyl bromides with alkynes and furans has been shown to furnish highly substituted aromatic rings. Penta- and hexasubstituted aromatic rings have also been prepared by the thermolysis of suitably substituted alkynes under microwave conditions. Tetrasubstituted pyridines can also be prepared using nitriles instead of alkynes. This work will provide
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Taherali, Farhan, Nerisha Chouhan, Fanjin Wang, et al. "Impact of Peptide Structure on Colonic Stability and Tissue Permeability." Pharmaceutics 15, no. 7 (2023): 1956. http://dx.doi.org/10.3390/pharmaceutics15071956.

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Most marketed peptide drugs are administered parenterally due to their inherent gastrointestinal (GI) instability and poor permeability across the GI epithelium. Several molecular design techniques, such as cyclisation and D-amino acid (D-AA) substitution, have been proposed to improve oral peptide drug bioavailability. However, very few of these techniques have been translated to the clinic. In addition, little is known about how synthetic peptide design may improve stability and permeability in the colon, a key site for the treatment of inflammatory bowel disease and colorectal cancer. In th
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Holst, Pia Bachmann, Uffe Anthoni, Carsten Christophersen, et al. "Cyclisations of Tryptophans. IV. Cyclisation of Nb-Acyl-L-Tryptophanamides." Acta Chemica Scandinavica 52 (1998): 683–93. http://dx.doi.org/10.3891/acta.chem.scand.52-0683.

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Joyce, Liam M., Anthony C. Willis, Christopher J. T. Hyland та Stephen G. Pyne. "Gold- and Silver-Catalysed Cyclisation Reactions of β-Amino Allenes". Australian Journal of Chemistry 71, № 9 (2018): 682. http://dx.doi.org/10.1071/ch18197.

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Herein we report the formation of pyrrolines and tetrahydropyridines from the cyclisation reactions of β-amino allenes by both AuI and AgI catalysts in yields ranging from 5 to 70 %. AuI catalysts favour a 5-endo-dig cyclisation before rapid rearrangement to the 5-exo-dig product, while AgI favours a 6-endo-trig cyclisation. We also report the first known Ag2O catalysed cyclisation reaction of an allene which occurred in good yield (61 %).
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Palík, Miroslav, Jozef Kožíšek, Peter Koóš, and Tibor Gracza. "Palladium-catalysed cyclisation of alkenols: Synthesis of oxaheterocycles as core intermediates of natural compounds." Beilstein Journal of Organic Chemistry 10 (September 3, 2014): 2077–86. http://dx.doi.org/10.3762/bjoc.10.216.

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The study of Pd-catalysed cyclisation reactions of alkenols using different catalytic systems is reported. These transformations affect the stereoselective construction of mono- and/or bicyclic oxaheterocyclic derivatives depending on a starting alkenol. The substrate scope and proposed mechanism of Pd-catalysed cyclisation reactions are also discussed. Moreover, the diastereoselective Pd-catalysed cyclisation of appropriate alkenols to tetrahydrofurans and subsequent cyclisation provided properly substituted 2,5-dioxabicyclo[2.2.1]heptane and 2,6-dioxabicyclo[3.2.1]octane, respectively. Such
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Ferguson, Jayne L., Marie A. Squire, and Christopher M. Fitchett. "Photochemical and oxidative cyclisation of tetraphenylpyrroles." Organic & Biomolecular Chemistry 15, no. 44 (2017): 9293–96. http://dx.doi.org/10.1039/c7ob02537h.

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The cyclisation of tetraphenylpyrroles under complementary conditions allows controlled cyclisation giving products dependent on N-substitution, with both tandem rearrangement and halogenation being observed.
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Dissertations / Theses on the topic "Cyclisation"

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Sukirthalingam, Sukanthini. "Palladium catalysed cyclisation processes." Thesis, Queen's University Belfast, 1990. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.335444.

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Chakraborty, Reena. "Cyclisation using bifunctional silanes." Thesis, University of Nottingham, 1991. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.335197.

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Wilmshurst, Martin Philip. "Fluoroalkyl radical cyclisation reactions." Thesis, University College London (University of London), 1998. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.286192.

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Bird, Andrew James. "Zirconium-mediated cyclisation reactions." Thesis, University of York, 1996. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.319766.

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Sykes, Bridget Maree. "Reductively triggered internal cyclisation reactions." Thesis, University of Auckland, 1994. http://hdl.handle.net/2292/1977.

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Reductively triggered internal cyclisation reactions have been investigated as a prodrug system for the hypoxia selective release of aromatic nitrogen mustards. The observed pseudo-first-order rate coefficients of cyclisation of several model 2-aminoaryl-acetamides and propanamides have been measured. Cyclisation was observed to be strongly influenced by stereochemistry, whereas electron withdrawal from the amine-bearing ring resulted in a comparatively modest slowing of the rate of cyclisation. Protonation of the leaving group appeared to increase the rate of cyclisation, while changes in 4-s
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Nilsson, Paul Andrew. "Radical cyclisation reactions of carbonyls." Thesis, Brunel University, 2002. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.270101.

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Pilling, Adam Wesley. "Site Isolation in Cyclisation Cascades." Thesis, University of Manchester, 2008. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.492762.

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This thesis concerns the exploitation of the site isolation concept in cascade sequences that facilitate rapid construction of complex polycyclic molecules. Site isolation is the anchoring of mutually destructive reagents onto solid supports to prevent their mutual deactivation.
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Nodes, William. "Novel intramolecular organocatalytic cyclisation reactions." Thesis, University of Reading, 2010. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.541961.

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Young, Adrian R. "Free radical cyclisation of imines." Thesis, Loughborough University, 1996. https://dspace.lboro.ac.uk/2134/15357.

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Introduction. The free radical cyclisation reaction onto an unsaturated bond is a well known synthetic pathway, where a wide range of cyclic compounds can be produced form acyclic starting materials. Up until recent years, free radical addition to multiple bonds other than carbon-carbon had been little studied. Nowadays there is much information available of radical addition to carbonyl, thiocarbonyl, nitrile and oxime ether (C=NOR) functional groups. However there has been surprisingly little detailed study of similar reactions involving imines (C=NR) or hydrazones (C=NNHR). Monocyclisation.
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Cecil, Alexander Richard Liam. "Asymmetric oxidative cyclisation of dienes." Thesis, University of Southampton, 2004. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.402065.

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Books on the topic "Cyclisation"

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Tinkl, Michael. Stereocontrolled iron-mediated cyclisation routes to heterocycles. University of East Anglia, 1994.

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Filik, Robert Paul. Synthesis of nitrogen containing heterocycles via radical cyclisation. typescript, 2000.

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Idris, Ziad Moh'd. Synthesis and cyclisation of 2-benzamido-1-phenylcyclohexanols. University of Salford, 1988.

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Byrne, Maeve. The synthesis and cyclisation of 2-bromo-3-ethoxypropanones. University College Dublin, 1998.

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Martin, Marie. The preparation and cyclisation of 5'- and 6'-Azachalcones. University College Dublin, 1995.

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Piet, Dennis P. Transannular cyclisation reactions of the germacrane system mediated by enzymes from Cichorium intybus. Landbouwuniversiteit Wageningen, 1996.

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Harmata, Michael. Advances in cycloaddition. JAI Press, 1999.

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Carruthers, W. Cycloaddition reactions in organic synthesis. Pergamon, 1990.

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Lehn, J. M. Aspects de la chimie des compose s macrocycliques: Notes re dige es, augmente es et actualise es. InterEditions, 1991.

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Ansari, Farzana Latif. Electrocyclic reactions: From fundamentals to research. Wiley-VCH, 1999.

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Book chapters on the topic "Cyclisation"

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Blanco-Urgoiti, Jaime, Gema Domínguez, Javier Pérez-Castells, et al. "Cyclisation Reactions." In Catalysts for Fine Chemical Synthesis, Volume 3, Metal Catalysed Carbon-Carbon Bond-Forming Reactions. John Wiley & Sons, Ltd, 2005. http://dx.doi.org/10.1002/0470862017.ch10.

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Markó, István E. "Electroorganic Cyclisation of Oxygen-Containing Compounds." In Novel Trends in Electroorganic Synthesis. Springer Japan, 1998. http://dx.doi.org/10.1007/978-4-431-65924-2_2.

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Louie, Janis. "N-Heterocyclic Carbene Complexes in Cyclisation Reactions." In Catalysis by Metal Complexes. Springer Netherlands, 2010. http://dx.doi.org/10.1007/978-90-481-2866-2_5.

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Gilbert, B. C., and C. W. McCleland. "Cyclisation of γ-Arylalkanols Via Aryl Radical-Cation and Alkoxyl Radical Intermediates." In Organic Free Radicals. Springer Berlin Heidelberg, 1988. http://dx.doi.org/10.1007/978-3-642-73963-7_60.

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Fernández-García, Elisabet, José J. Ríos, Manuel Jarén-Galán, and Antonio Pérez-Gálvez. "Intramolecular Cyclisation as Structural Transformation of Carotenoids During Processing of Paprika (Capsicum annuumL.) and Paprika Oleoresins." In ACS Symposium Series. American Chemical Society, 2013. http://dx.doi.org/10.1021/bk-2013-1134.ch017.

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MacCorquodale, Finlay, and John C. Walton. "Unusual Transannular Radical Cyclisations." In Organic Free Radicals. Springer Berlin Heidelberg, 1988. http://dx.doi.org/10.1007/978-3-642-73963-7_55.

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Rowan, S. J., P. A. Brady, and J. K. M. Sanders. "Selectivity in Thermodynamic Cyclisations of Cinchona Alkaloid Derivatives." In Molecular Recognition and Inclusion. Springer Netherlands, 1998. http://dx.doi.org/10.1007/978-94-011-5288-4_89.

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Ward, Robert S. "Cyclisation versus polymerisation." In Bifunctional Compounds. Oxford University Press, 1994. http://dx.doi.org/10.1093/hesc/9780198558088.003.0011.

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This chapter reviews the competition between cyclization and polymerization and states that this can be influenced in several ways, such as through varying the concentration of the solution. It demonstrates a method that can be used to promote cyclization at the expense of polymerization, namely to carry out the reaction in dilute solution so that the probability of an intermolecular reaction taking place is reduced. It also talks about the entropy factor, a measure of the probability of the two ends of the chain coming into contact with one another. The chapter explains that the enthalpy fact
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"CHAPITRE 2 Cyclisation." In Aspects de la chimie des composés macrocycliques. EDP Sciences, 1991. http://dx.doi.org/10.1051/978-2-7598-0265-4.c006.

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"CHAPITRE 2 Cyclisation." In Aspects de la chimie des composés macrocycliques. EDP Sciences, 1991. https://doi.org/10.1051/978-2-86883-365-5.c006.

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Conference papers on the topic "Cyclisation"

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Stadelmann, Sacha, Stéphane Mayor, Roger Marti, and Marc Mathieu. "Depsipeptide cyclisation: Lactonization vs. Lactamisation." In 35th European Peptide Symposium. Prompt Scientific Publishing, 2018. http://dx.doi.org/10.17952/35eps.2018.166.

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Arrasate, Sonia, Esther Lete, Nuria Sotomayor, and Media Abdullah. "Stereoselective Synthesis of Thiaerythrinanes via Parham Cyclisation." In The 11th International Electronic Conference on Synthetic Organic Chemistry. MDPI, 2007. http://dx.doi.org/10.3390/ecsoc-11-01318.

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Kohler, Armin, and Bernd Bertsche. "Cyclisation of Safety Diagnoses: Influence on the Evaluation of Fault Metrics." In 2021 Annual Reliability and Maintainability Symposium (RAMS). IEEE, 2021. http://dx.doi.org/10.1109/rams48097.2021.9605716.

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Allen, Scott G., Richard M. Meade, Robert J. Williams, and Jody M. Mason. "An Intracellular Cyclisation Screen Generates Short Helical Peptide Inhibitor of Alpha Synuclein Aggregation." In 37th European Peptide Symposium. The European Peptide Society, 2024. http://dx.doi.org/10.17952/37eps.2024.p1068.

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Amaral, André F. C., Guilherme D. R. Matos, Inês S. Resck, and Elaine R. Maia. "Stereochemical and 13C NMR study in order to characterize intermediates obtained by cyclisation of diisoxazoledilactone." In 14th Brazilian Meeting on Organic Synthesis. Editora Edgard Blücher, 2013. http://dx.doi.org/10.5151/chempro-14bmos-r0322-1.

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Raposo, M., Ana Sampaio, and G. Kirsch. "Synthesis of Arylamino-thieno-oxobutanamides and Reactivity Studies on the Cyclisation with the Lawesson's Reagent." In The 8th International Electronic Conference on Synthetic Organic Chemistry. MDPI, 2004. http://dx.doi.org/10.3390/ecsoc-8-01947.

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