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Journal articles on the topic 'Cycloartane derivatives'

Author: Grafiati

Published: 5 June 2025

Last updated: 1 August 2025

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1

Cabrera, Gabriela M., Mariana Gallo, and Alicia M. Seldes. "Cycloartane Derivatives fromTillandsia usneoides." Journal of Natural Products 59, no. 4 (1996): 343–47. http://dx.doi.org/10.1021/np960075+.

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2

Nyemba, Anne-Marie, Theophile Ngando Mpondo, Joseph D. Connolly, and David S. Rycroft. "Cycloartane derivatives from Garcinia lucida." Phytochemistry 29, no. 3 (1990): 994–97. http://dx.doi.org/10.1016/0031-9422(90)80067-q.

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3

Furlan, Maysa, Nídia Franca Roque, and Wilson Wolter Filho. "Cycloartane derivatives from Guarea trichilioides." Phytochemistry 32, no. 6 (1993): 1519–22. http://dx.doi.org/10.1016/0031-9422(93)85170-v.

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4

Kim, Nanyoung, SeonJu Park, Nguyen Xuan Nhiem, Jae-Hyoung Song, Hyun-Jeong Ko, and Seung Hyun Kim. "Cycloartane-type triterpenoid derivatives and a flavonoid glycoside from the burs of Castanea crenata." Phytochemistry 158 (February 28, 2019): 135–41. https://doi.org/10.1016/j.phytochem.2018.11.001.

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Kim, Nanyoung, Park, SeonJu, Nhiem, Nguyen Xuan, Song, Jae-Hyoung, Ko, Hyun-Jeong, Kim, Seung Hyun (2019): Cycloartane-type triterpenoid derivatives and a flavonoid glycoside from the burs of Castanea crenata. Phytochemistry 158: 135-141, DOI: 10.1016/j.phytochem.2018.11.001, URL: http://dx.doi.org/10.1016/j.phytochem.2018.11.001

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5

Nagashima, Fumihiro, Yuki Tabuchi, Takuya Ito, Liva Harinantenaina, and Yoshinori Asakawa. "Terpenoids, Flavonoids and Acetogenins from Some Malagasy Plants." Natural Product Communications 11, no. 2 (2016): 1934578X1601100. http://dx.doi.org/10.1177/1934578x1601100205.

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Humulanes, drimanes, ent-kaurane, lupane, cycloartane, flavanone, flavones and quinol derivatives were isolated from Malagasy Cussonia vantsilana, Helichrysum gymnocephalum, Phyllarthron madagascariense, Gomphocarpus fructicosus, Cinnamosma sp. and C. fragrans, and their structures elucidated by using extensive NMR analysis. A mixture of a few flavones and/or lupane triterpene showed antimicrobial activity against Mycobacterium smegmatis and Pseudomonas aeruginosa.

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6

Debelec-Butuner, Bilge, Mert Burak Ozturk, Ozgur Tag, Ismail Hakki Akgun, Erdal Bedir, and Kemal Sami Korkmaz. "Characterization of Cycloartane-Type Sapogenol Derivatives for Prostate Cancer Chemoprevention." Proceedings 1, no. 10 (2017): 985. http://dx.doi.org/10.3390/proceedings1100985.

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7

Watanabe, Kazuki, Yoshihiro Mimaki, Haruhiko Fukaya, and Yukiko Matsuo. "Cycloartane and Oleanane Glycosides from the Tubers of Eranthis cilicica." Molecules 24, no. 1 (2018): 69. http://dx.doi.org/10.3390/molecules24010069.

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Phytochemical analysis of the tubers of Eranthis cilicica was performed as part of our continuous study on the plants of the family Ranunculaceae, which resulted in the isolation of eleven new cycloartane glycosides (1–11) and one new oleanane glycoside (13), together with one known oleanane glycoside (12). The structures of the new compounds were determined by extensive spectroscopic analysis, including two-dimensional (2D) NMR, and enzymatic hydrolysis followed by either X-ray crystallographic or chromatographic analysis. The aglycone (1a) of 2 and its C-23 epimer (8a), and the oleanane glyc

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8

R., Banik, and Dinda B. "Chemical constituents of Artocarpus chaplasha." Journal of Indian Chemical Society 93, Mar 2016 (2016): 333–36. https://doi.org/10.5281/zenodo.5639088.

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Department of Chemistry, Tripura University, Suryamaninagar-799 022, Tripura, India <em>E-mail </em>: dindabtu@gmail.com <em>Manuscript received 05 September 2012, revised 29 May 2015, accepted 26 November 2015</em> Chemical investigation of the stem bark of Artocarpus chaplasha (Moraceae) afforded cycloartenyl acetate (1), 24-methylenecycloartanyl acetate (2), lupenyl acetate (3), (23E)-25-hydroxycycloart-23-en-3β-ol (4), (23E)-25- methoxycycloart-23-en-3β-ol (5), (23E)-25-hydroperoxycycloart-23-en-3β-ol (6), β-sitosterol (7) and stigmasterol (8). Compounds 2, 4-6 and

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9

Kim, Nanyoung, SeonJu Park, Nguyen Xuan Nhiem, Jae-Hyoung Song, Hyun-Jeong Ko, and Seung Hyun Kim. "Cycloartane-type triterpenoid derivatives and a flavonoid glycoside from the burs of Castanea crenata." Phytochemistry 158 (February 2019): 135–41. http://dx.doi.org/10.1016/j.phytochem.2018.11.001.

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10

Ning, Ruo-nan, Hong-min Wang, Yu Shen, et al. "Lithocarpic acids O–S, five homo-cycloartane derivatives from the cupules of Lithocarpus polystachyus." Bioorganic & Medicinal Chemistry Letters 24, no. 23 (2014): 5395–98. http://dx.doi.org/10.1016/j.bmcl.2014.10.036.

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11

Wang, Hongmin, Ruonan Ning, Yu Shen, et al. "Lithocarpic Acids A–N, 3,4-seco-Cycloartane Derivatives from the Cupules of Lithocarpus polystachyus." Journal of Natural Products 77, no. 8 (2014): 1910–20. http://dx.doi.org/10.1021/np500379f.

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12

Liu, Yue, Liangyu Yang, Hong Wang, and Yongai Xiong. "Recent Advances in Antiviral Activities of Triterpenoids." Pharmaceuticals 15, no. 10 (2022): 1169. http://dx.doi.org/10.3390/ph15101169.

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Triterpenoids, important secondary plant metabolites made up of six isoprene units, are found widely in higher plants and are studied for their structural variety and wide range of bioactivities, including antiviral, antioxidant, anticancer, and anti-inflammatory properties. Numerous studies have demonstrated that different triterpenoids have the potential to behave as potential antiviral agents. The antiviral activities of triterpenoids and their derivatives are summarized in this review, with examples of oleanane, ursane, lupane, dammarane, lanostane, and cycloartane triterpenoids. We concen

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13

Debeleç-Bütüner, Bilge, Mert Burak Öztürk, Özgür Tağ та ін. "Cycloartane-type sapogenol derivatives inhibit NFκB activation as chemopreventive strategy for inflammation-induced prostate carcinogenesis". Steroids 135 (липень 2018): 9–20. http://dx.doi.org/10.1016/j.steroids.2018.04.005.

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14

Romero, Juan Carlos, Adriana Martínez-Vázquez, Maribel Pineda Herrera, et al. "Synthesis, anti-inflammatory activity and modeling studies of cycloartane-type terpenes derivatives isolated from Parthenium argentatum." Bioorganic & Medicinal Chemistry 22, no. 24 (2014): 6893–98. http://dx.doi.org/10.1016/j.bmc.2014.10.028.

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15

Jöhrer, Stuppner, Greil, and Çiçek. "Structure-Guided Identification of Black Cohosh (Actaea racemosa) Triterpenoids with In Vitro Activity against Multiple Myeloma." Molecules 25, no. 4 (2020): 766. http://dx.doi.org/10.3390/molecules25040766.

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Black cohosh is a well-established medicinal plant and preparations of its rootstock are used for the treatment of mild climacteric complaints. The compounds considered responsible for the therapeutic effect are triterpene glycosides, characterized by a cycloartane scaffold and a pentose moiety. Because some of these triterpenoids were found to exhibit relevant cytotoxic effects against human breast cancer cells, we decided to investigate their activity on multiple myeloma cell lines NCI-H929, OPM-2, and U266. In a systematic approach, we initially tested three known cytotoxic compounds of thr

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16

Li, Xiao, Wei Wang, Yi Fan, et al. "Anticancer efficiency of cycloartane triterpenoid derivatives isolated from Cimicifuga yunnanensis Hsiao on triple-negative breast cancer cells." Cancer Management and Research Volume 10 (December 2018): 6715–29. http://dx.doi.org/10.2147/cmar.s185387.

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17

Costa, Hermenegildo R., Inês Simão, Helena Silva, Paulo Silveira, Artur M. S. Silva, and Diana C. G. A. Pinto. "Aglaomorpha quercifolia (L.) Hovenkamp & S. Linds a Wild Fern Used in Timorese Cuisine." Foods 10, no. 1 (2021): 87. http://dx.doi.org/10.3390/foods10010087.

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Aglaomorpha quercifolia (L.) Hovenkamp & S. Linds is an extensively used species in traditional medicinal systems in several areas of the world due to some important medicinal properties such as antioxidant, antibacterial, analgesic, and anti-inflammatory activities. In East Timor, different parts of this fern are used either as remedies or as food. The ingestion of a broth made from its rhizome improves lactation, and young fronds of this fern are boiled and eaten with rice by the locals. Nevertheless, its chemical profile is far from being established. The present work aims to establish

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18

T.P., KUKINA, and ELSHIN I.A. "TERPENE AND ALIPHATIC PRODUCTS OF SAPONIFICATION OF THE ETHER EXTRACT OF EUPHORBIA VIRGATA WALDST. ET KIT." Chemistry for Sustainable Development 32, no. 4 (2024): 485–91. http://dx.doi.org/10.15372/csd2024582.

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The composition of the lipophilic components of Euphorbia virgata Waldst. et Kit. has been studied. Acidic and neutral components have been identified using gas-liquid chromatography with mass spectrometric detection (GC-MS) following alkaline hydrolysis of the whole extract. The plant material was extracted with methyl tert-butyl ether (MTBE). Total acids isolated during sample preparation were analysed after methylation with diazomethane. The composition of the neutral components of unsaponifiable residue was studied without derivatisation, but after separation by column chromatography on si

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19

Napolitano, Assunta, Seref Akay, Angela Mari, Erdal Bedir, Cosimo Pizza, and Sonia Piacente. "An analytical approach based on ESI-MS, LC–MS and PCA for the quali–quantitative analysis of cycloartane derivatives in Astragalus spp." Journal of Pharmaceutical and Biomedical Analysis 85 (November 2013): 46–54. http://dx.doi.org/10.1016/j.jpba.2013.06.021.

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20

Thao, Nguyen Phuong, Jang Hoon Kim, Bui Thi Thuy Luyen, Nguyen Tien Dat, and Young Ho Kim. "In silico investigation of cycloartane triterpene derivatives from Cimicifuga dahurica (Turcz.) Maxim. roots for the development of potent soluble epoxide hydrolase inhibitors." International Journal of Biological Macromolecules 98 (May 2017): 526–34. http://dx.doi.org/10.1016/j.ijbiomac.2017.02.023.

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21

Hill, Robert A., and Joseph D. Connolly. "Triterpenoids." Natural Product Reports 32, no. 2 (2015): 273–327. http://dx.doi.org/10.1039/c4np00101j.

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This review covers the isolation and structure determination of triterpenoids reported during 2012 including squalene derivatives, lanostanes, holostanes, cycloartanes, cucurbitanes, dammaranes, euphanes, tirucallanes, tetranortriterpenoids, quassinoids, lupanes, oleananes, friedelanes, ursanes, hopanes, serratanes, isomalabaricanes and saponins; 348 references are cited.

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22

Hill, Robert A., and Joseph D. Connolly. "Triterpenoids." Natural Product Reports 34, no. 1 (2017): 90–122. http://dx.doi.org/10.1039/c6np00094k.

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This review covers the isolation and structure determination of triterpenoids reported during 2013 including squalene derivatives, lanostanes, holostanes, cycloartanes, cucurbitanes, dammaranes, euphanes, tirucallanes, tetranortriterpenoids, quassinoids, lupanes, oleananes, friedelanes, ursanes, hopanes, serratanes, isomalabaricanes and saponins; 350 references are cited.

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23

Gao, Feng, Tom J. Mabry, Ferdinand Bohlmann, and Jasmin Jakupovic. "Cycloartanone derivatives from Viguiera dentata." Phytochemistry 25, no. 6 (1986): 1489–91. http://dx.doi.org/10.1016/s0031-9422(00)81319-9.

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24

КУКИНА, Т. П., and И. А. ЕЛШИН. "Terpene and Aliphatic Products of Saponification of the Ether Extract of Euphorbia virgata Waldst. et Kit." Химия в интересах устойчивого развития 32, no. 4 (2024): 502–8. http://dx.doi.org/10.15372/khur2024582.

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Изучен состав липофильных компонентов молочая лозного (Euphorbia virgata Waldst. et Kit.). Кислые и нейтральные компоненты идентифицировали при помощи газо-жидкостной хроматографии с масс-спектрометрической детекцией (ГХ-МС) после щелочного гидролиза цельного экстракта. В качестве экстрагента сырья использован метил-трет-бутиловый эфир (МТБЭ). Выделенные в процессе пробоподготовки суммарные кислоты анализировали после метилирования диазометаном. Состав нейтральных компонентов неомыляемого остатка исследовали без дериватизации, но после разделения методом колоночной хроматографией на силикагеле

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25

Cabrera, Gabriela M., Mariana Gallo, and Alicia M. Seldes. "A 3,4-seco-cycloartane derivative from Tillandsia usneoides." Phytochemistry 39, no. 3 (1995): 665–66. http://dx.doi.org/10.1016/0031-9422(95)00076-j.

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26

Flores-Rosete, Graciela, and Mariano Martínez-Vázquez. "Anti-inflammatory and Cytotoxic Cycloartanes from Guayule (Parthenium Argentatum)." Natural Product Communications 3, no. 3 (2008): 1934578X0800300. http://dx.doi.org/10.1177/1934578x0800300318.

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The need for the discovery and development of new pharmaceuticals for the treatment of cancer demands that all approaches to drug discovery should be exploited. Among the possible approaches, the one from natural products has made many unique and vital contributions to drug discovery. This mini review focuses on researches made in our laboratory on cycloartanes isolated from Parthenium argentatum, as well as some of its derivatives, in order to obtain potential anti-inflammatory and anti-cancer agents.

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27

INADA, Akira, Takako SORANO, Hiroko MURATA, Yuka INATOMI, Dedy DARNAEDI, and Tsutomu NAKANISHI. "Diamide Derivatives and Cycloartanes from the Leaves of Aglaia elliptica." CHEMICAL & PHARMACEUTICAL BULLETIN 49, no. 9 (2001): 1226–28. http://dx.doi.org/10.1248/cpb.49.1226.

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28

Zambrano, E. Elisabeth, Adriana G. Casas, Gabriela M. Di Venosa, María L. Uriburu, Fernando J. Duran, and Jorge A. Palermo. "Synthesis and cytotoxicity evaluation of A-ring derivatives of cycloartanone." Phytochemistry Letters 21 (September 2017): 200–205. http://dx.doi.org/10.1016/j.phytol.2017.06.021.

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29

Inada, Akira, Takako Sorano, Hiroko Murata, Yuka Inatomi, Dedy Darnaedi, and Tsutomu Nakanishi. "ChemInform Abstract: Diamide Derivatives and Cycloartanes from the Leaves of Aglaia elliptica." ChemInform 33, no. 7 (2010): no. http://dx.doi.org/10.1002/chin.200207242.

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30

Omneya Eid, Shahira Ezzat, Mariam Gonaid та Mouchira A. Choucry. "Novel Cycloartan derivative with genetic and metabolic proৎiling oftwo Crassulaceae species". International Journal of Research in Pharmaceutical Sciences 11, SPL4 (2020): 2997–3012. http://dx.doi.org/10.26452/ijrps.v11ispl4.4594.

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Crassula tetragona L. and Crassula ovata (Mill). are ornamental species of family Crassulaceae. Although this family is known for its high medicinal values, however, there is no much work considering the two species. Hence, this study represents the first comparative investigation of the genetic and metabolic profiling of the aerial part of both species. In this study, an examination of the genetic properties of both plants were accomplished, quantitative estimation of the main chemical classes of both species were also performed, investigation of the lipoidal matter of the plants and the majo

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31

Sowjanya, Pulipati, and Babu Puttagunta Srinivasa. "In Silico Prediction of Biomarkers from Amaranthus tricolor (L) Targeted against HIV-1 Protease." Research Journal of Biotechnology 18, no. 1 (2022): 7–14. http://dx.doi.org/10.25303/1801rjbt07014.

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Acquired immunodeficiency syndrome is caused by a retrovirus human immunodeficiency virus (HIV). Resistance to antiviral drugs is alarming in antiretroviral therapy and medical management of HIV-infected patients. Thus, identifying novel antiviral drugs is critical and medicinal plants are an excellent source for such discoveries. The current study aimed to isolate and characterize the chemical constituents from leaves of Amaranthus tricolor (L) and to discover novel HIV-1 protease inhibitors. Amaranthus tricolor methanolic extract (ATME) was fractionated into chloroform and aqueous phases. Th

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32

Khvorost, Olha, and Yehenia Zudova. "Research of the primary metabolites of Astragalus dasyanthus herb." Annals of Mechnikov Institute, no. 4 (December 4, 2023): 73–78. https://doi.org/10.5281/zenodo.10256797.

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<strong>Introduction.</strong> One of the directions of complex tepary of hypertension is the application of medicinal plant raw materials and preparations based on them. One of these plants is <i>Astragalus dasyanthus</i> Pall. <i>Fabaceae</i> legume family. It is a perennial herbaceous plant. The raw material is grass. The chemical composition of raw materials is quite diverse: polysaccharides arabin and basorin, mucus, organic acids, triterpene saponins (cycloartane derivatives), flavonoids (kaempferol, quercetin, isorhamnetin and their glycosides), mineral compounds (compounds of iron

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33

Hernández‐Flandes, Atzin, Simón Hernández‐Ortega, Teresa Ramírez‐Apan, Leticia Rocha‐Zavaleta, Noemi Silva‐Jimenez та Mariano Martínez‐Vázquez. "Synthesis of Cycloartan‐16β‐ol from 16β 24R‐Epoxy‐Cycloartane and their Cytotoxicity Evaluation against Human Cancer Cell Lines." Chemistry & Biodiversity, 29 березня 2024. http://dx.doi.org/10.1002/cbdv.202301346.

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AbstractIt was found that Argentatins A and B triterpenoids make up approximately 20–30 % of the waste resin produced from the industrial processes to isolate rubber from P. argentatum. We have developed an efficient protocol for synthesizing cycloartane‐16β‐ol derivatives by opening the oxepane ring of argentatin B acetate (2) with BF3‐OEt2. Although three new cycloartenol derivatives showed high cytotoxicity against PC‐3 and HCT‐15 cancer cell lines, nevertheless, the best results were obtained for (16β,24R) ‐(16,24‐epoxy‐cycloartan‐2(1H)‐ylidene) acetate (14), compound with intact oxepane r

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34

Ye, Jianghai, Chuanyan Xu, Chenliang Zhao, et al. "Three New Cycloartane Triterpenoids From the Caulis of Kadsura longipedunculata." Chemistry & Biodiversity, July 15, 2025. https://doi.org/10.1002/cbdv.202501406.

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ABSTRACTThree unprecedented cycloartane triterpenoids (1–3) together with five known congeners (4–8) were isolated for the first time from the medicinal plant Kadsura longipedunculata. Their structural diversity was characterized by distinct skeletal modifications: compound 1 represents a rare 3,4‐seco‐cycloartane derivative featuring a 7‐membered ester A‐ring formed via Baeyer‐Villiger oxidation, compound 2 is a schisanartane‐type nortriterpenoid with unique 3,4:9,10‐diseco structural motifs, while compound 3 exhibits an unprecedented 18,28‐demethylated cycloartane skeleton. In addition, five

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35

Ekiz Dinçman, Güner, Zeki Aytaç, and İhsan Çalış. "Turkish Astragalus Species: Botanical Aspects, Secondary Metabolites, and Biotransformation." Planta Medica, November 13, 2024. http://dx.doi.org/10.1055/a-2444-3252.

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Abstract Astragalus is a widespread genus comprising approximately 3500 species, both annual and perennial, found across Asia, Europe, Africa, and the Americas. In Turkey, it is represented by 63 sections and 485 taxa with a high endemism ratio (51%). In traditional medicine, the roots of various Astragalus species represent very old and well-known drugs used for antiperspirant, diuretic, and tonic purposes, as well as for the treatment of nephritis, diabetes, leukemia, and uterine cancer. The genus Astragalus is the richest source of cycloartane-type compounds, which display a diverse range o

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36

Tsamo, Armelle Tontsa, Edwige P. Fodja Saah, Moses K. Langat, Pierre Mkounga, Alain François Kamdem Waffo, and Augustin Ephrem Nkengfack. "Antimycobacterial cycloartane derivatives from the roots of Trichilia welwistchii C. DC (Meliaceae)." Zeitschrift für Naturforschung B, August 4, 2021. http://dx.doi.org/10.1515/znb-2021-0060.

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Abstract Chemical investigation of the roots of Trichilia welwitschii yielded a cycloartane type terpenoid 28,29-bis-norcycloart-24-en-3β,4α,6α-triol (1), isolated as pure compound for the first time, three coumarins and three sterols. New cycloartane derivatives (1a) and (1b+1c) were obtained by hemi-synthetic reaction of compound 1. The structures of 1a–c were established by spectroscopic methods including 1D and 2D-NMR analysis, HR-EIMS, chemical transformations and by comparison of these data with those of related compounds. Evaluated for their antimycobacterial potential, compound 1 and 1

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Küçüksolak, Melis, Sinem Yılmaz, Petek Ballar-Kırmızıbayrak, and Erdal Bedir. "Potent telomerase activators from a novel sapogenin via biotransformation utilizing Camarosporium laburnicola, an endophytic fungus." Microbial Cell Factories 22, no. 1 (2023). http://dx.doi.org/10.1186/s12934-023-02069-3.

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Abstract Background Cycloartane-type triterpenoids possess important biological activities, including immunostimulant, wound healing, and telomerase activation. Biotransformation is one of the derivatization strategies of natural products to improve their bioactivities. Endophytic fungi have attracted attention in biotransformation studies because of their ability to perform modifications in complex structures with a high degree of stereospecificity. Results This study focuses on biotransformation studies on cyclocephagenol (1), a novel cycloartane-type sapogenin from Astragalus species, and i

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38

Wang, Chen, Hai‐di Wu, Xiao‐dong Mu, and Jing‐yong Sun. "Synthesis and Anti‐Aging Activity Exploration of Cycloastragenol Derivatives." ChemistrySelect 10, no. 12 (2025). https://doi.org/10.1002/slct.202405831.

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AbstractThere has been limited research on the preparation of analogues of cycloartane‐type sapogenols (9,19‐cyclolanostanes). Therefore, we decided to use cycloastragenol as a lead compound for structural modification. The semi‐synthetic derivatives were mainly obtained by reactions such as oxidation, alkylation, acylation, and aldol reactions. In this study, we synthesized 27 cycloastragenol derivatives, 20 of which were novel compounds, and evaluated their protective activity on t‐BHP‐induced C2C12 cell growth inhibition and anti‐aging activities. We found that most derivatives inhibited t‐

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39

Nam, Nguyen Hoai, Phan Van Kiem, Ninh Khac Ban, et al. "Chemical constituents of Mallotus macrostachyus growing in Vietnam and cytotoxic activity of some cycloartane derivatives." Phytochemistry Letters, July 2011. http://dx.doi.org/10.1016/j.phytol.2011.07.007.

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40

Yang, Yu-pei, Yu-qing Jian, Yong-bei Liu, et al. "Triterpenoids From Kadsura coccinea With Their Anti-inflammatory and Inhibited Proliferation of Rheumatoid Arthritis-Fibroblastoid Synovial Cells Activities." Frontiers in Chemistry 9 (December 9, 2021). http://dx.doi.org/10.3389/fchem.2021.808870.

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One new 3,4-seco-17,13-friedo-lanostane triterpenoid heilaohuacid A (1), one new 3,4-seco-17,14-friedo-lanostane triterpenoid heilaohuacid B (2), five new 3,4-seco-lanostane triterpenoids heilaohuacids C-D (3–4) and heilaohumethylesters A-C (7–9), one new 3,4-seco-cycloartane triterpenoid heilaohuacid E (5), and one new intact-lanostane triterpenoid heilaohuacid F (6), together with twenty-two known analogues (10–31), were isolated from heilaohu. Their structures were determined using HR-ESI-MS data, 1D and 2D NMR spectra, 13C NMR calculations, and electronic circular dichroism (ECD) calculati

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41

Rodrigues Garcez, Fernanda, Patrick da Silva Mirowski, Gabriela da Silva Coutinho de Araújo Bueno, et al. "Chemical Composition and Evaluation of Antibacterial, Antibiofilm and Mutagenic Potentials of a Propolis Sample from the Atlantic Forest of Midwest Brazil." Chemistry & Biodiversity, September 28, 2023. http://dx.doi.org/10.1002/cbdv.202301238.

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Sixteen triterpenoids with various skeletal types, five phenylpropanoid derivatives, and two flavonoids were isolated from a propolis sample produced by Apis mellifera collected in the Atlantic Forest of Midwest Brazil. Among these compounds, six triterpenes, namely 3β,20R‐dihydroxylanost‐24‐en‐3‐yl‐palmitate, (23E)‐25‐methoxycycloartan‐23‐en‐3‐one, 24‐methylenecycloartenone, epi‐lupeol, epi‐a‐amyrin, and epi‐β‐amyrin are being reported for the first time in propolis, while cycloartenone, (E)‐cinnamyl benzoate, and (E)‐cinnamyl cinnamate are new findings in Brazilian propolis. The presence of

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Shkondrov, Aleksandar, and Ilina Krasteva. "HIGH RESOLUTION LC-MS/MS SCREENING FOR SECONDARY METABOLITES IN BULGARIAN SPECIES OF GENUS Astragalus L." Química Nova, 2021. http://dx.doi.org/10.21577/0100-4042.20170730.

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The phytochemical content of some Astragalus species distributed in Bulgarian flora has been previously studied. Among other compounds, flavoalkaloids, acylated flavonoids, flavonoid triglycosides and cycloartane saponins have been isolated so far. The composition of the rest of the representatives of this genus in Bulgaria is not explored yet. The aim of this study was to perform a screening for the presence of selected rare secondary metabolites (flavoalkaloids, acylated flavonoids, flavonoid triglycosides and cycloartane saponins) in selected Astragalus species. Samples were collected in di

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GUTIÉRREZ, Pablo A., and Benjamín A. ROJANO. "DOCKING OF TYROSINASE CICLOARTANE INHIBITORS." Vitae 16, no. 2 (2009). http://dx.doi.org/10.17533/udea.vitae.1937.

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Berenjenol (21:24-epoxy-24-methyl-cicloartane) isolated from leaves of Oxandra cf. xylopioides (Annonaceae), and its synthetic derivatives Berenjenol-3-acetate and 3-Oxoberenjenol are tyrosinase inhibitors (EC 1.14.18.1). These compounds are triterpenoids type cycloartanes, whose structure-activity relationship has been studied on similar compounds. However, the mechanism of inhibition of these molecules is not well understood. This paper present the results of a docking study between Berenjenol and its derivatives on tyrosinase enzyme that provides a rational framework for understanding the a

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Piegang, Basile Nganmegne, Ignas Bertrand Nzedong Tigoufack, David Ngnokam, et al. "Cycloartanes from Oxyanthus pallidus and derivatives with analgesic activities." BMC Complementary and Alternative Medicine 16, no. 1 (2016). http://dx.doi.org/10.1186/s12906-016-1075-3.

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Oliveira, N., A. Duarte та A. Madureira. "Antibacterial activity of acyl and epoxide derivatives of β-sitosterol and cycloartanes". Planta Medica 76, № 12 (2010). http://dx.doi.org/10.1055/s-0030-1264796.

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