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Relevant bibliographies by topics / Cyclocondensation

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Academic literature on the topic 'Cyclocondensation'

Author: Grafiati

Published: 4 June 2021

Last updated: 26 July 2025

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Journal articles on the topic "Cyclocondensation"

1

Mei, Zemin, Haifeng Yu та Peiqiu Liao. "Regioselective Synthesis of Isomeric 3-[1-Substituted Pyrazol-3(5)-yl]indoles from β-Ethylthio-β-indolyl-α,β-unsaturated Ketones". Synthesis 52, № 14 (2020): 2111–20. http://dx.doi.org/10.1055/s-0040-1707999.

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An efficient and highly regioselective synthesis of isomeric 3-[1-substituted pyrazol-3(5)-yl]indoles has been developed by the acid-mediated regioselective cyclocondensation reaction of β-ethyltho-β-indolyl-α,β-unsaturated ketones and monosubstituted hydrazines. In the presence of 1 equivalent of AcOH in refluxing EtOH, the cyclocondensation reaction of β-ethyltho-β- indolyl-α,β-unsaturated ketones with monosubstituted hydrazines yielded 3-(1-substituted pyrazol-5-yl)indoles in excellent yields, while 3-(1-substituted pyrazol-3-yl)indoles were obtained in good yields when the cyclocondensatio

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2

Stadlbauer, Wolfgang, El-Sayed Badawey, Gerhard Hojas, Peter Roschger, and Thomas Kappe. "Malonates in Cyclocondensation Reactions." Molecules 6, no. 4 (2001): 338–52. http://dx.doi.org/10.3390/60400338.

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P, Paliwal, Mujalda V, Rao Jetti S, Babu G.N., and S. Jain. "Synthesis and in vitro antimicrobial evaluation of 2,4-diamino-8,8-dimethyl-6-oxo-5-(heteroaryl)-6,7,8,9-tetrahydro-5H-chromeno[2,3-b] pyridine-3-carbonitrile." International Journal of Drug Design and Discovery 3, no. 4 (2025): 930–34. https://doi.org/10.37285/ijddd.3.4.7.

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Four-component one pot cyclocondensation of heteroaromatic aldehyde1, malononitrile2, 5,5-dimethyl-cyclohexane-1,3-dione (dimedone)3 and 1,4-diazabicyclo [2.2.2] octane4 in aqueous-ethanol after initial Knoevenagel condensation, subsequent Michael and final heterocyclization reactions gave substituted and functionalized pyrano(c)chromene derivatives.5 These pyrano(c)chromenes on reaction with malononirile result in the formation of diversely substituted linear tricyclic chromenopyridine6, via cyclocondensation followed by heterocyclization. All the compounds are biologically active against var

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Müller, Thomas, та Natascha Breuer. "Consecutive Alkynylation–Michael Addition–Cyclocondensation (AMAC) Multicomponent Syntheses of α-Pyrones and α-Pyridones". Synthesis 50, № 14 (2018): 2741–52. http://dx.doi.org/10.1055/s-0037-1610129.

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A novel consecutive three-component synthesis of α-pyrones is based upon an alkynylation–Michael addition–cyclocondensation (AMAC) sequence, starting from (hetero)aroyl chloride and terminal alkyne to furnish the alkynone which reacts with malonates to give the α-pyrones in moderate to very good yields. By concatenating ammonolysis of the α-pyrones, an alkynylation–Michael addition–cyclocondensation–ammonolysis (AMACA) synthesis of α-pyridones can be conceived. α-Pyridone products with and without ester functionality are obtained in moderate yields.

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Kozlov, V. A., K. V. Novikov, T. G. Mokeeva, and S. A. Kuz’mina. "Cyclocondensation of oxoacids with urea." Russian Journal of General Chemistry 83, no. 7 (2013): 1467–68. http://dx.doi.org/10.1134/s1070363213070323.

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6

Sokolov, V. B., A. Yu Aksinenko, T. A. Epishina, T. V. Goreva, and I. V. Martynov. "Cyclocondensation of trifluorolactates with isocyanates." Russian Chemical Bulletin 62, no. 4 (2013): 1020–21. http://dx.doi.org/10.1007/s11172-013-0134-x.

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Wang, Yizhong, and Joseph M. Ready. "Cyclocondensation of Amino-propargyl Silanes." Organic Letters 14, no. 9 (2012): 2308–11. http://dx.doi.org/10.1021/ol300724c.

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Yu, Haifeng, Wenju Wang, Kehua Wang та Xue Zhang. "Complementary and Regioselective Synthesis of Isomeric 3-[Isoxazol-3(or 5)-yl]indoles from β-Ethylthio-β-indolyl-α,β-unsaturated Ketones". Synthesis 53, № 11 (2021): 1989–99. http://dx.doi.org/10.1055/s-0040-1706658.

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AbstractA simple and efficient method for the complementary and regioselective synthesis of isomeric 3-(isoxazol-5-yl)indoles and 3-(isoxazol-3-yl)indoles has been developed by the regioselective cyclocondensation reaction of β-ethylthio-β-indolyl-α,β-unsaturated ketones and hydroxylamine hydrochloride. It was found that the cyclocondensation reaction in the presence of excess NaOEt in refluxing EtOH gives 3-(isoxazol-5-yl)indoles in good yields, whereas using NaOAc in boiling AcOH gives 3-(isoxazol-3-yl)indoles in good yields.

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Sapariya, Nirav H., Beena K. Vaghasiya, Rahul P. Thummar, et al. "Synthesis, characterization, in silico molecular docking study and biological evaluation of a 5-(phenylthio) pyrazole based polyhydroquinoline core moiety." New Journal of Chemistry 41, no. 19 (2017): 10686–94. http://dx.doi.org/10.1039/c7nj01962a.

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Dobiaš, Juraj, Marek Ondruš, Gabriela Addová, and Andrej Boháč. "Switchable highly regioselective synthesis of 3,4-dihydroquinoxalin-2(1H)ones from o-phenylenediamines and aroylpyruvates." Beilstein Journal of Organic Chemistry 13 (July 10, 2017): 1350–60. http://dx.doi.org/10.3762/bjoc.13.132.

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3-Acylmethylidene-3,4-dihydroquinoxalin-2(1H)-ones are compounds which possess a wide range of physical and pharmaceutical applications. These compounds can be easily prepared by cyclocondensation of o-phenylenediamines and aroylpyruvates. Unsymmetrically substituted o-phenylenediamines can be obtained form regioisomeric mixtures of 3,4-dihydroquinoxalin-2(1H)-ones. It is often quite difficult to get a pure regioisomer and determine its structure without controlling the reaction selectivity and exploitation of complex NMR techniques (HSQC, NOESY, HMBC). This article examines the regioselectivi

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Dissertations / Theses on the topic "Cyclocondensation"

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Leftwich, Timothy Ray. "Modification of silicon-based substrates with cyclocondensation and cycloaddition reactions." Access to citation, abstract and download form provided by ProQuest Information and Learning Company; downloadable PDF file, 111 p, 2010. http://proquest.umi.com/pqdweb?did=1992491831&sid=7&Fmt=2&clientId=8331&RQT=309&VName=PQD.

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Rocheville-Divorne, Catherine. "Etude de la réactivité de Delta² thiazolines avec les esters acétyléniques addition cycloaddition cyclocondensation /." Grenoble 2 : ANRT, 1987. http://catalogue.bnf.fr/ark:/12148/cb376094479.

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Ghirardi, Elena. "Enantio- and Diastereoselective Cyclocondensation Reactions. Stereocontrolled Access to Azabicycles and Application to Natural Product Synthesis." Doctoral thesis, Universitat de Barcelona, 2016. http://hdl.handle.net/10803/398789.

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The first objective of this Thesis was the study of the preparation of octhydro-1H-cyclopenta[b]pyridines and octahydro-1H-indoles, through the synthesis of (R)-phenylglycinol derived tricyclic lactams. Following the previous reported methodology a carbon substituent would be present at the carbocyclic ring and we planned to find the conditions for controlling its absolute configuration. Unfortunately, the reaction of ketoester 4 and ketoacid 7, provided undesired enamines 8 and 9. On the other hand, the reaction of ketoacid derivatives 16 and 17 with (R)-phenylglycinol led to a mixture of epi

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Rocheville-Divorne, Catherine. "Etude de la réactivité de delta 2 thiazolines avec les esters acétyléniques : addition cycloaddition cyclocondensation." Aix-Marseille 3, 1987. http://www.theses.fr/1987AIX30003.

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Roze, Jean-Claude. "Réactions de cyclocondensation méthodes d'accès à des dérivés thiaziniques, application à la synthèse de céphèmes polysubstitués /." Grenoble 2 : ANRT, 1986. http://catalogue.bnf.fr/ark:/12148/cb37600897s.

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Muraro, Paulo Isaias Rossato. "Uso de microondas na síntese de 3-alquil(aril)-5-hidróxi-5-triclorometil-4,5-diidro-1h-pirazol-1-carboxiamida." Universidade Federal de Santa Maria, 2005. http://repositorio.ufsm.br/handle/1/10399.

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A series of 3-alkyl and 3-aryl-5-hydroxy-5-trichloromethyl-4,5-dihydro-1Hpirazoles-1-carboxiamide that possess biological activity they were synthesized, in good yeld, through the cyclocondensation, in microwaves, of 4-alcoxi-1,1,1-trihalometyl-3alquen-2-onas with semicarbazyde chloride using MeOH/H2O as solvent. The advantage obtained with the use of irradiation of microwaves in relation to the classic methodology it is the decrease of the time reacional and revenue increase as it will be demonstrated.<br>Uma série de 3-alquil(aril) 5-hidroxi 5-triclorometil-4,5-diidropirazol-1-carboxiamida,

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Hamid, Abdulkareem. "Synthèse des analogues hétérocycliques des alcaloïdes, Camptothécine, Rutaecarpine, et Luotonine : agents à fort potentiel cytotoxique." Le Havre, 2006. http://www.theses.fr/2006LEHA0010.

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Dans le cadre d'une nouvelle thématique de recherche dans notre laboratoire, nous avons investi la synthèse des analogues d'alcaloïdes Camptothécine, Rutaecarpine et Luotonine reconnus pour leur fort potentiel cytotoxique. Dans la première partie de ce travail, consacrée à la synthèse d’analogues de la Camptothécine, nous avons exposé une nouvelle stratégie pour la construction des squelettes quinoléinopyrrolo-isoquinoléine, contenant l'enchaînement cyclique A→B→C→D→E de la Camptothécine et la 22-hydroxyacuminatine. Celle-ci est basée sur l'utilisation de la chimie des ions N-acyliminiums en a

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8

Prola, Liziê Daniela Tentler. "Síntese de 3-haloacetil-4-metilquinolinas utilizando líquido iônico sob irradiação de micro-ondas." Universidade Federal de Santa Maria, 2011. http://repositorio.ufsm.br/handle/1/10492.

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Conselho Nacional de Desenvolvimento Científico e Tecnológico<br>The synthesis of a series of 3-haloacetyl-4-methyl-quinolines from the cyclocondensation reaction of 4-alkoxyvinyl ketones [R1C(O)CH=C(R2)(OCH3), where R1 = CF3, CCl3, CHCl2, CF2Cl, CF2CF3 and R2 = Me, Et, Pr, Bu, i-Bu, i- Pent] with 2-aminoacetophenone is reported. The reaction was performed in the presence of p-toluene sulphonic acid (p-TsOH), ionic liquid ([HMIM][TsO]) and under microwave irradiation. The molar ratio of the reactants 4-alkoxyvinyl ketone and 2-aminoacetophenone was of 1:1, respectively, for the quinoline with

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9

Nasr, El Dine Assaad. "Développement de nouvelles méthodes de synthèse en chimie de fluor et préparation de molécules bioactives." Thesis, Rennes 1, 2015. http://www.theses.fr/2015REN1S158/document.

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Ce travail s'inscrit dans le cadre d'un programme de collaboration entre l'Université Libanaise et l'université de Rennes 1. La thèse est divisée en deux parties :Chimie du fluor : synthèse de nouveaux hétérocycles portant des chaînes latérales fluorées ; chimie médicinale : recherche de nouvelles molécules à visées anticancéreuses. La première partie se compose de trois chapitres : dans le premier chapitre, des intermédiaires de synthèse de type énones fluorées ont été synthétisés par une voie originale, et leur réactivité en cyclocondensation a été étudiée pour obtenir de pyrazolines et de p

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10

Vargas, Pâmela Schütz de. "Reações de β-enaminodicetonas com ncn dinucleófilos: obtenção de pirimidinas e sistemas heterocíclicos fundidos". Universidade Federal de Santa Maria, 2016. http://repositorio.ufsm.br/handle/1/4288.

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Conselho Nacional de Desenvolvimento Científico e Tecnológico<br>In this study the reactivity of β-enamino diketones [RC(O)C(=CHNMe2)C(O)CO2Et, R = C6H5, 4-Me-C6H4, 4-MeO-C6H4, 4-F-C6H4, 4-Br-C6H4, 4-NO2-C6H4, tien-2-il] with NCN bisnucleophiles as amidine and guanidine was investigated. The tiopirimidines ethyl 2-benzylthio-pyrimidine-4-carboxylates, (65-91 %) and Ethyl 2-metiltiopirimidine-4-carboxylates (69-91 %) were obtained in a highly regioselective manner by cyclocondensation reaction of β-enamino diketones with benzylisothiourea hydrochloride and methylisothiourea sulfate, respectivel

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Book chapters on the topic "Cyclocondensation"

1

Chen, Xiangyu. "NHC-Catalyzed Cyclocondensation of α,β-Unsaturated Carboxylic Acids." In New Strategies for N-Heterocyclic Carbenes Catalyzed Annulations. Springer Singapore, 2016. http://dx.doi.org/10.1007/978-981-10-2899-1_4.

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Rodriquez, Manuela, and Maurizio Taddei. "Synthesis of Heterocycles via Microwave-Assisted Cycloadditions and Cyclocondensations." In Topics in Heterocyclic Chemistry. Springer Berlin Heidelberg, 2006. http://dx.doi.org/10.1007/7081_005.

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3

Bansal, R. K., and Neelima Gupta. "[3 + 2] Cyclocondensation." In Five-Membered Hetarenes with Three or More Heteroatoms. Georg Thieme Verlag KG, 2004. http://dx.doi.org/10.1055/sos-sd-013-00969.

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Bansal, R. K., and Neelima Gupta. "[4 + 1] Cyclocondensation." In Five-Membered Hetarenes with Three or More Heteroatoms. Georg Thieme Verlag KG, 2004. http://dx.doi.org/10.1055/sos-sd-013-01178.

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Pindur, U., and T. Lemster. "Cyclocondensation at Indolequinone." In Quinones and Heteroatom Analogues. Georg Thieme Verlag KG, 2006. http://dx.doi.org/10.1055/sos-sd-028-00560.

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Hajos, G., and Z. Riedl. "Ring Closure by Cyclocondensation." In Five-Membered Hetarenes with Two Nitrogen or Phosphorus Atoms. Georg Thieme Verlag KG, 2002. http://dx.doi.org/10.1055/sos-sd-012-00841.

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Bansal, R. K., and Neelima Gupta. "Cyclocondensation with Phosphorus Trichloride." In Five-Membered Hetarenes with Three or More Heteroatoms. Georg Thieme Verlag KG, 2004. http://dx.doi.org/10.1055/sos-sd-013-01062.

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Bansal, R. K., and Neelima Gupta. "Cyclocondensation with Hexamethylphosphorous Triamide." In Five-Membered Hetarenes with Three or More Heteroatoms. Georg Thieme Verlag KG, 2004. http://dx.doi.org/10.1055/sos-sd-013-01063.

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Bansal, R. K., and Neelima Gupta. "By [3 + 2] Cyclocondensation." In Five-Membered Hetarenes with Three or More Heteroatoms. Georg Thieme Verlag KG, 2004. http://dx.doi.org/10.1055/sos-sd-013-01079.

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Perst, H., and C. Klenke. "Cyclocondensation of Substituted Acetic Acids." In Five-Membered Hetarenes with One Chalcogen and One Additional Heteroatom. Georg Thieme Verlag KG, 2002. http://dx.doi.org/10.1055/sos-sd-011-00068.

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Conference papers on the topic "Cyclocondensation"

1

Anichina, K. "SYNTHESIS AND ANTINEMATODAL ACTIVITY STUDIES OF SOME FUSED TRIAZINOBENZIMIDAZOLES." In International Trends in Science and Technology. RS Global Sp. z O.O., 2020. http://dx.doi.org/10.31435/rsglobal_conf/30122020/7351.

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4-Aryl-3,4-dihydro[1,3,5]triazino[1,2-a]benzimidazole-2-amines 3a-f were synthesized in the reaction of cyclocondensation between 2-guanidinobenzimidazole and versatilebenzaldehydes. Structures of all prepared compounds were confirmed by IR, 1H NMR spectroscopyand elemental analysis.Antinematodal activity in vitro of the substances was investigated using isolated Trichinella spiralis muscle larvae. The tested triazonobenzimidazoles showed different activity depending on the substituent R in their moleculeas the derivatives substituted with a hydroxyl group demonstrated the best anti-Trichinell

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Andrighetto, Rosália, Helio G. Bonacorso, Jussara Navarini, Nícolas Krüger, Marcos A. P. Martins, and Nilo Zanatta. "Highly Efficient Synthesis of CF3-Containing 7-Aminoquinolines From Cyclocondensation Reaction of Trifluoroacetyl Enamine Precursors." In 14th Brazilian Meeting on Organic Synthesis. Editora Edgard Blücher, 2013. http://dx.doi.org/10.5151/chempro-14bmos-r0008-1.

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Siniutsich, Julia, Anna Pietkievich, Anastasiya Yermolinskaya, et al. "New Nanocatalitic Fe₃O₄/CeO₂ Composite in the Cyclocondensation Reaction." In 2021 IEEE 11th International Conference Nanomaterials: Applications & Properties (NAP). IEEE, 2021. http://dx.doi.org/10.1109/nap51885.2021.9568550.

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Krunić, Mihajlo J., Jelena Z. Penjišević, Slađana Kostić-Rajačić, Vladimir B. Šukalović, Deana B. Andrić, and Ivana I. Jevtić. "Pyrazole/tacrine derivatives as potential cholinesterase inhibitors." In 2nd International Conference on Chemo and Bioinformatics. Institute for Information Technologies, University of Kragujevac, 2023. http://dx.doi.org/10.46793/iccbi23.567k.

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Two new tacrine/pyrazole conjugates were designed, synthesized, and pharmacologically evaluated for their inhibitory activity toward acetylcholinesterase (AChE) and butyrylcholinesterase (BuChE). A scalable and cost-efficient synthetic route was developed, and key reaction steps for the synthesis of compounds 4a,b were nucleophilic substitution of α-aroylketene dithioacetals with tacrine intermediates, followed by cyclocondensation of respective N,S-acetals with hydrazine hydrate. The preliminary pharmacological evaluation revealed high inhibitory activities of 4a,b toward AChE (180 and 259 nM

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