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Journal articles on the topic 'Cyclodextrine'

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Published: 4 June 2021

Last updated: 26 July 2025

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1

Cabal, Jiří, Kamil Kuča, Lucie Ševelová-Bartošová, and Vlastimil Dohnal. "Cyclodextrines as Functional Agents for Decontamination of the Skin Contaminated by Nerve Agents." Acta Medica (Hradec Kralove, Czech Republic) 47, no. 2 (2004): 115–18. http://dx.doi.org/10.14712/18059694.2018.75.

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Three decontamination solutions of β-cyclodextrines were prepared. Their abilities to decontamine rat skin contamined with nerve agent soman were tested. Decontamination efficacy of the tested cyclodextrine solutions was compared with the same decontamination means but without the cyclodextrines. The efficacy of tested decontaminants was evaluated by the assessment of the ID50 values. Two decontamination prescriptions with cyclodextrines (tetraborate buffer and tetraborate buffer with acetone) do not show significantly better decontamination efficacies in comparison with prescriptions without

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2

Bijwar, Rahul, and Harshal Tare. "Solubility and Taste Masked Behaviour of Cyclodextrin Molecular Inclusion Complex of Lumefantrin." INTERNATIONAL JOURNAL OF DRUG DELIVERY TECHNOLOGY 13, no. 04 (2023): 1151–55. http://dx.doi.org/10.25258/ijddt.13.4.04.

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Lumefantrine is an antimalarial drugs used especially for pediatric persons. β-Cyclodextrine is used to improve the taste of lumefantrine by forming complexes with them by the solvent evaporation method, respectively. β-Cyclodextrine prevent the release of drug in the saliva. Lumefantrine is a bitter drug. So masking of bitter taste in the formulation is a prerequisite as it improves the compliance of the patient and product value. Lumefantrine with β-cyclodextrin in a drug-polymer ratio 1:1 gave complete taste masking with a satisfactory result obtained in term of in-vivo and in-vitro evaluat

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3

Odeh, Fadwa, Fedaa Adaileh, Walhan Alshaer та ін. "Synthesis of Mono-Amino Substituted γ-CD: Host–Guest Complexation and In Vitro Cytotoxicity Investigation". Molecules 27, № 5 (2022): 1683. http://dx.doi.org/10.3390/molecules27051683.

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Cyclodextrins (CDs) are cyclic oligosaccharides which can trap hydrophobic molecules and improve their chemical, physical, and biological properties. γ-CD showed the highest aqueous solubility with the largest cavity diameter among other CD types. The current study describes a direct and easy method for nucleophilic mono-aminos to be substituted with γ-CD and tested for their ability to host the guest curcumin (CUR) as a hydrophobic drug model. The mass spectrometry and NMR analyses showed the successful synthesis of three amino-modified γ-CDs: mono-6-amino-6-deoxy-cyclodextrine (γ-CD-NH2), mo

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4

Sparr, H. J. "Cyclodextrine." Der Anaesthesist 51, no. 11 (2002): 929–30. http://dx.doi.org/10.1007/s00101-002-0401-y.

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5

Ilic, Slavica, Sandra Konstantinovic, G. Gojgic-Cvijovic, Dragisa Savic та Vlada Veljkovic. "The influence of Schiff base inclusion complexes with β-cyclodextrine on antibiotic production by Streptomyces hygroscopicus CH-7". Chemical Industry 69, № 1 (2015): 9–15. http://dx.doi.org/10.2298/hemind131113012i.

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A media consisting of isatin-Schiff bases and its inclusion complexes with ?-cyclodextrine was developed to maximize the production of antibiotics Hexaene H-85 and Azalomycine ? by Streptomyces hygroscopicus CH-7. The media with ?-cyclodextrine inclusion complex of isatin-3-thiosemicarbazone resulted in the maximum antibiotics concentration of 493 ?g/cm3 for Hexaene H-85 and 191 ?g/cm3 for Azalomycine B. The production of Hexaene H-85 and Azalomycine is higher when ?-cyclodextrine complex is added as a nitrogen source, comparing to pure isatin-Schiff base. The maximum concentration of hexaene

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6

Buschmann, Hans-Jürgen, Dierk Knittel, Karin Beermann, and Eckhard Schollmeyer. "Cyclodextrine und Textilien." Nachrichten aus der Chemie 49, no. 5 (2001): 620–22. http://dx.doi.org/10.1002/nadc.20010490509.

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7

Borchard-Tuch, Claudia. "Cyclodextrine - die Verpackungskünstler." Chemie in unserer Zeit 39, no. 2 (2005): 137–39. http://dx.doi.org/10.1002/ciuz.200590015.

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8

Jezequel, D., A. Mayaffre та P. Letellier. "Étude potentiométrique de la stabilité de complexes tensioactif–β-cyclodextrine". Canadian Journal of Chemistry 69, № 12 (1991): 1865–71. http://dx.doi.org/10.1139/v91-270.

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The complexation constants K of β-cyclodextrine with 13 ammonium surfactants were determined by a potentiometric method using electrodes selective to amphiphilic ions. Especially for C12, C14, and C16 tails, a model that provides for the formation of a second complex (β-CD)2M+, with a K1/K2 ratio of about 600, provides a good fit with the experimental curves. Results show a poor influence of the polar group, for example in the case of the dodecyl chain. On the other hand, the pK1 values and the hydrophobic tail length are linked by a linear relation up to n = 12 carbon atoms; beyond, pK1 tends

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9

Bijwar, Rahul, and Harshal Tare. "Solubility and Taste Masked Behaviour of Cyclodextrin Molecular Inclusion Complex of Artemether." INTERNATIONAL JOURNAL OF PHARMACEUTICAL QUALITY ASSURANCE 14, no. 04 (2023): 862–66. http://dx.doi.org/10.25258/ijpqa.14.4.06.

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Artemether by forming a complex with β-cyclodextrine (βCD) is used to improve solubility and taste masked by the kneading method. Artemether with β-cyclodextrine complex prepared with βCD in a drug-polymer ratio 1:1 gave complete taste masking with the satisfactory result obtained in term of in-vivo and in-vitro evaluation. The standard calibration curve of Artemether shows a slope of 0.0154 and a correlation coefficient of 0.9992. Compatibility studies show that drugs are compatible with polymers. Solubility studies show that the solubility of drug are increased in Phosphate buffer 6.8 by suc

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10

Grgac, Sandra Flinčec, та Rajna Malinar. "Application of Environment-Friendly Processes Aimed at Bonding Β-Cyclodextrine onto Cellulosic Materials". Fibres and Textiles in Eastern Europe 26, № 5(131) (2018): 63–69. http://dx.doi.org/10.5604/01.3001.0012.2533.

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The impact of the pre-treatment of cellulose material in NaOH solution and of microwave radiation on the mechanism of crosslinking β-cyclodextrin with cellulose was investigated in this paper. Citric acid and Na-hypophosphite as catalysts were applied for better crosslinking. Inclusion compounds with tea tree essential oil and cyclodextrines grafted onto cotton fabric were made in order to verify that cavities were available for inclusion compounds. The permanence of β-CD on the cellulose fabrics treated was tested by ISO 6330:2012. The properties and structure of the materials treated were ch

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11

Glasmacher, Axel, Archibald Prentice, Marcus Gorschlüter, et al. "Itraconazole Prevents Invasive Fungal Infections in Neutropenic Patients Treated for Hematologic Malignancies: Evidence From a Meta-Analysis of 3,597 Patients." Journal of Clinical Oncology 21, no. 24 (2003): 4615–26. http://dx.doi.org/10.1200/jco.2003.04.052.

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Purpose: Efficacy of antifungal prophylaxis has not yet been convincingly proven in numerous trials of various antifungals. New evidence and the anti-Aspergillus efficacy of itraconazole prompted a new look at the data for the prevention of invasive fungal infections. Patients and Methods: Randomized, controlled studies with itraconazole for antifungal prophylaxis in neutropenic patients with hematologic malignancies were identified from electronic databases and hand searching. Results: Thirteen randomized trials included 3,597 patients who were assessable for invasive fungal infections. Itrac

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12

Vilgis, Thomas. "Cyclodextrine: wenn Chemie Physik auslöst." Physik in unserer Zeit 46, no. 5 (2015): 258. http://dx.doi.org/10.1002/piuz.201590091.

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13

Pashupati Nath Sharma, Pashupati Nath Sharma. "A Study of Hydroxypropyl Α-Cyclodextrin and Α-Cyclodextrin Inclusion Complexity". Journal of Advances and Scholarly Researches in Allied Education 19, № 3 (2022): 5–10. https://doi.org/10.29070/ag4ehh15.

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Cyclodextrins are generated with a range of readily available enzymes for the treatment of ordinary starch. Along with amylase, cyclodextrin glycosylotransferase is commonly used. The first is to liquify starch by thermal treatment or amylase and add CGTase to the enzyme conversion. The synthesis of all three types of cyclodextrins is possible at ratios that depend strictly on the enzyme used. Each CGTase has an independent synthesis relationship. Cyclodextrins are filtered according to their different water solubility CDs that are very poorly water-soluble can be easily crystallised while the

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14

Patel, V. P., M. C. Gohel, and R K Parikh. "In Vitro Dissolution Enhancement of Felodipine." Indo Global Journal of Pharmaceutical Sciences 01, no. 02 (2011): 194–205. http://dx.doi.org/10.35652/igjps.2011.19.

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Purpose: With the introduction of combinatorial chemistry and high throughput screening, the properties of new chemical entities shifted towards higher molecular weight and increasing lipophilicity that results in decreasing aqueous solubility. It is not surprising that many drug candidates have poor water solubility since the initial selection of drug candidates are based on activity alone. Other physiochemical and biopharmaceutical properties such as permeability, biopharmaceutics and metabolism are rarely considered during the selection process. The aim of this study was to increase dissolu

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15

Margheritis, C., та C. Sinistri. "β-cyclodextrine and Water: Semiempirical Calculations". Zeitschrift für Naturforschung A 51, № 8 (1996): 950–56. http://dx.doi.org/10.1515/zna-1996-0810.

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Abstract AM1 and PM3 calculations were carried out on ß-cyclodextrine (ß-CD) undecahydrate in the experimental conformation at 120 K. The calculated ß-CD/water interaction energies are very small and indicative for each water molecule of an unfavorable condition in respect to that of pure water. The conformationally optimized system was also studied: ß-CD appears highly symmetrical with negligible dipole moment, mainly because of the circular arrangement of the single vectors. Primary hydroxyls can easily rotate, while the secondary ones are stabilized by heteroannular hydrogen bonds and homoa

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16

Margheritis, C., A. Marini, and C. Sinistri. "Thermodynamics of ß-cyclodextrine/water Interactions." Zeitschrift für Naturforschung A 52, no. 4 (1997): 348–50. http://dx.doi.org/10.1515/zna-1997-0409.

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Abstract From a purely enthalpic standpoint, the ß-CD hydration, as studied by semiempirical calculations, appears improbable, in contrast to experiment. For the spontaneous hydration process, a compensation mechanism, connected with substrate stabilization and/or entropy increase, is suggested on the basis of simple thermodynamic considerations. The analysis is done on the basis of a single parameter Ew (> 0), which represents the energy needed to transfer a mole of water from the liquid to the ß-CD absorbed phase.The model, although simple, allows predictions largely consistent with the e

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17

Nag, Ashis, Rina Dutta, Nitin Chattopadhyay та Kankan Bhattacharyya. "Effect of cyclodextrine cavity size on twisted intramolecular charge transfer emission: Dimethylamino benzonitrile in β-cyclodextrine". Chemical Physics Letters 157, № 1-2 (1989): 83–86. http://dx.doi.org/10.1016/0009-2614(89)87212-4.

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18

Nyamba, Isaie, Bertrand W. Goumbri, B. Charles Sombié, Hermine Zimé Diawara, Josias B. G. Yaméogo та Rasmané Semdé. "Influence de l’hydroxypropyl-β-Cyclodextrine et de l’hydroxypropyl-γ-Cyclodextrine sur la solubilité aqueuse de l’acide ellagique". Journal Africain de Technologie Pharmaceutique et Biopharmacie (JATPB) 3, № 2 (2024): 45–52. https://doi.org/10.57220/jatpb.v3i2.195.

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Sur la base d’études antérieures, ayant démontré une efficacité in vitro de l’huile essentielle de Cymbopogon giganteus Chiov. (Poaceae) sur les germes impliqués dans l’angine de gorge, l’objectif de cette étude était de développer un collutoire à base de cette huile pour le traitement de l’angine. L’huile d’olive a été utilisée comme phase dispersée, le TWEEN 60 et SPAN 60 comme tensio-actifs pour stabiliser l’émulsion pour le collutoire. Plusieurs essais utilisant différentes proportions d’huile d’olive ont été nécessaires avant d’obtenir la préparation la plus stable. La caractérisation du

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19

Labes, Antje, and Peter Schönheit. "Unusual Starch Degradation Pathway via Cyclodextrins in the Hyperthermophilic Sulfate-Reducing Archaeon Archaeoglobus fulgidus Strain 7324." Journal of Bacteriology 189, no. 24 (2007): 8901–13. http://dx.doi.org/10.1128/jb.01136-07.

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ABSTRACT The hyperthermophilic archaeon Archaeoglobus fulgidus strain 7324 has been shown to grow on starch and sulfate and thus represents the first sulfate reducer able to degrade polymeric sugars. The enzymes involved in starch degradation to glucose 6-phosphate were studied. In extracts of starch-grown cells the activities of the classical starch degradation enzymes, α-amylase and amylopullulanase, could not be detected. Instead, evidence is presented here that A. fulgidus utilizes an unusual pathway of starch degradation involving cyclodextrins as intermediates. The pathway comprises the

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20

Wenz, Gerhard. "Cyclodextrine als Bausteine supramolekularer Strukturen und Funktionseinheiten." Angewandte Chemie 106, no. 8 (1994): 851–70. http://dx.doi.org/10.1002/ange.19941060804.

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21

Haiehem, Sakina, Hanane Messiad, Tarek Yousfi та ін. "Intermolecular interactions of Guanosine/β-Cyclodextrine and Guanosine-hydroxypropyl/β-Cyclodextrin inclusion complexes using DFT calculation". STUDIES IN ENGINEERING AND EXACT SCIENCES 5, № 2 (2024): e11649. https://doi.org/10.54021/seesv5n2-649.

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In this work the study investigates intermolecular interactions in Guanosine (Guo) into β-cyclodextrin (β-CD) and their derivatives, such as hydroxypropyl-βCD (HPβCD) inclusion complexes using Density Functional Theory including dispersion correction (DFT-D3) method using the following functional, B3LYP/6-31G basis set in both gaz and aqueous phases. These complexes geometries were optimized and the final results were examined and contrasted. The global chemical reactivity descriptors, the Fukui function, and the HOMO and LUMO energies were calculated. The TD-DFT method was used to determine t

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22

Duvivier, Stéphane, Mirielle Turmine, and Pierre Letellier. "Solubilité de la beta-cyclodextrine dans les mélanges eau - nitrate d'éthylammonium à 25°C." Canadian Journal of Chemistry 76, no. 8 (1998): 1210–14. http://dx.doi.org/10.1139/v98-139.

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β-Cyclodextrin solubilities were determined in water - ethylammonium nitrate (EAN) mixtures at 25°C. EAN is a molten salt at room temperature (θ f = 14°C). It is miscible with water in the whole range of mixtures. Unlike molecular solvents, addition of EAN to water involves a decrease of β-cyclodextrin solubility. In mixtures rich in salt, this solubility increases anew. β-Cyclodextrin solubility in pure salt is about 20 times the value in pure water. β-Cyclodextrin behavior in water-EAN mixtures can be easily described by assuming the presence in solution of a complex ion linking two molecule

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23

Dejean, A., P. Charpin, G. Folcher, R. Ducousso, and M. Matteodo. "Utilisation de la cyclodextrine en thérapeutique des radiocontaminations." Journal of the Less Common Metals 122 (August 1986): 604. http://dx.doi.org/10.1016/0022-5088(86)90467-4.

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24

Franke, Joachim, Thomas Merz, Hans-Willi Losensky, Walter M. M�ller, Ute Werner, and Fritz V�gtle. "Cyclodextrine und synthetische Wirthohlr�ume ? Vergleich der Komplexierungseigenschaften." Journal of Inclusion Phenomena 3, no. 4 (1985): 471–78. http://dx.doi.org/10.1007/bf00657499.

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25

König, Wilfried A., Sabine Lutz, and Gerhard Wenz. "Modifizierte Cyclodextrine - neue, hochenantioselektive Trennphasen für die Gaschromatographie." Angewandte Chemie 100, no. 7 (1988): 989–90. http://dx.doi.org/10.1002/ange.19881000729.

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26

Guy, Alain, Joël Doussot, Agnès Dallamaggiore та Robert Garreau. "Ouverture sélective d'époxydes styréniques substitués à l'aide d'azoture de lithium en présence de β-cyclodextrine". Canadian Journal of Chemistry 73, № 4 (1995): 599–603. http://dx.doi.org/10.1139/v95-077.

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Regio- and enantioselective opening of substituted styrenic epoxides by lithium azide in presence of β-cyclodextrin is described. The regioselectivity of the reaction is related to the hydrophobicity of the substrate, which governs its penetration inside the cavity of the cyclodextrin and is favorable to the β opening of the epoxide. The enantioselectivity observed during the kinetic resolution of the racemic epoxide is mainly dependent on the non-covalent interactions between the upper rim of the cyclodextrin and the epoxide. Keywords: β-cyclodextrin, inclusion complexes, regio- and stereocon

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27

Lavandier, CD, MP Pelletier та VC Reinsborough. "Surfactant Inclusions by Modified β-Cyclodextrins". Australian Journal of Chemistry 44, № 3 (1991): 457. http://dx.doi.org/10.1071/ch9910457.

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Binding constants for the inclusion of sodium alkane-1-sulfonates (C5-C10, C12) by four modified β- cyclodextrins (2,6-O-dimethyl-β-cyclodextrin, 2,3,6-O-trimethyl-β-cyclodextrin, hydroxypropyl-β-cyclodextrin and maltosyl-β-cyclodextrin ) were determined conductimetrically at 25°C. Binding increased with increasing length of the alkyl chain. Generally, the substituted β- cyclodextrins were no more effective as encapsulating agents than ordinary β- cyclodextrin with the persubstituted 2,3,6-O-trimethyl-β-cyclodextrin being the weakest.

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28

Briggner, L. E., X. R. Ni, F. Tempesti та I. Wadsö. "Microcalorimetric titration of β-cyclodextrine with adamantane-1-carboxylate". Thermochimica Acta 109, № 1 (1986): 139–43. http://dx.doi.org/10.1016/0040-6031(86)85015-8.

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29

Blanchemain, N., F. Chai, S. Haulon та ін. "Biological behaviour of an endothelial cell line (HPMEC) on vascular prostheses grafted with hydroxypropylgamma-cyclodextrine (HPγ-CD) and hydroxypropylbeta-cyclodextrine (HPβ-CD)". Journal of Materials Science: Materials in Medicine 19, № 6 (2008): 2515–23. http://dx.doi.org/10.1007/s10856-008-3388-3.

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30

Easton, Christopher J., Steven J. van Eyk, Stephen F. Lincoln, Bruce L. May, John Papageorgiou, and Michael L. Williams. "A Versatile Synthesis of Linked Cyclodextrins." Australian Journal of Chemistry 50, no. 1 (1997): 9. http://dx.doi.org/10.1071/c96168.

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Reactions of amino-substituted cyclodextrins with bis(3-nitrophenyl) oxalate, malonate, succinate and glutarate, and with diphenyl carbonate, afford a range of linked cyclodextrins. These include α- and β-cyclodextrin dimers, joined by substitution at either C6 or C3, and asymmetric species with a β-cyclodextrin bonded to an a-cyclodextrin and a C3-substituted cyclodextrin attached to a C6-substituted moiety.

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31

Zheng, Xi, Xiu Ling Ma, Hong Fang Xie, Shao Bin Li, Yu Xi Ren та Zhen Chen. "Imprinted β-Cyclodextrin Polymer for Recognition of Naringin". Advanced Materials Research 284-286 (липень 2011): 1850–53. http://dx.doi.org/10.4028/www.scientific.net/amr.284-286.1850.

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The objective of this study was to find out a kind of MIP which was suitable for recognizing NG in aqueous medium. A non-covalent NG-β-CD imprinted polymer was prepared by using β-cyclodextrine (β-CD) as a functional monomer, naringin (NG) as a template molecule and hexamethylene diisocyanate (HMDI) as cross linker. The binding property and selectivity were evaluated by the equilibrium binding experiment, its imprinting factors α is 1.39.

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32

Yhaya, Firdaus, Andrew M. Gregory, and Martina H. Stenzel. "Polymers with Sugar Buckets - The Attachment of Cyclodextrins onto Polymer Chains." Australian Journal of Chemistry 63, no. 2 (2010): 195. http://dx.doi.org/10.1071/ch09516.

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This Review summarizes the structures obtained when marrying synthetic polymers of varying architectures with cyclodextrins. Polymers with cyclodextrin pendant groups were obtained by directly polymerizing cyclodextrin-based monomers or by postmodification of reactive polymers with cyclodextrins. Star polymers with cyclodextrin as the core with up to 21 arms were usually obtained by using modified cyclodextrins as initiator or controlling agent. Limited reports are available on the synthesis of star polymers by arm-first techniques, which all employed azide-functionalized cyclodextrin and ‘cli

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33

Wang, Runmiao, Hui Zhou, Shirley W. I. Siu, Yong Gan, Yitao Wang, and Defang Ouyang. "Comparison of Three Molecular Simulation Approaches for Cyclodextrin-Ibuprofen Complexation." Journal of Nanomaterials 2015 (2015): 1–8. http://dx.doi.org/10.1155/2015/193049.

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Cyclodextrins are widely used for the solubilisation of poorly soluble drugs in the formulations. However, current cyclodextrin formulation development strongly depends on trial-and-error in the laboratory, which is time-consuming and high cost. The aim of this research was to compare three modeling approaches (Docking, molecular dynamics (MD), and quantum mechanics (QM)) for cyclodextrin/drug complexation. Ibuprofen was used as a model drug. Binding free energy from three simulation methods was calculated as an important parameter to compare with the experimental results. Docking results from

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34

Wang, Lei, Xuguo Duan та Jing Wu. "Enhancing the α-Cyclodextrin Specificity of Cyclodextrin Glycosyltransferase from Paenibacillus macerans by Mutagenesis Masking Subsite −7". Applied and Environmental Microbiology 82, № 8 (2016): 2247–55. http://dx.doi.org/10.1128/aem.03535-15.

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ABSTRACTCyclodextrin glycosyltransferases (CGTases) (EC 2.4.1.19) catalyze the conversion of starch or starch derivates into mixtures of α-, β-, and γ-cyclodextrins. Because time-consuming and expensive purification procedures hinder the widespread application of single-ingredient cyclodextrins, enzymes with enhanced specificity are needed. In this study, we tested the hypothesis that the α-cyclodextrin selectivity ofPaenibacillus maceransα-CGTase could be augmented by masking subsite −7 of the active site, blocking the formation of larger cyclodextrins, particularly β-cyclodextrin. Five singl

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35

Sivakumar, Ponnurengam M., Shohreh Peimanfard, Ali Zarrabi, Arezoo Khosravi, and Matin Islami. "Cyclodextrin-Based Nanosystems as Drug Carriers for Cancer Therapy." Anti-Cancer Agents in Medicinal Chemistry 20, no. 11 (2020): 1327–39. http://dx.doi.org/10.2174/1871520619666190906160359.

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Background and Objective: Cyclodextrins have been of great interest as excellent candidates for fabricating versatile nano-drug delivery systems due to their commercial availability, easy functionalization, low immunogenicity, biocompatibility and safety. The possibility of reversible inclusion complex formation between cyclodextrins and various guest molecules in association with versatile exclusive properties of cyclodextrins offer a route towards the fabrication of highly sophisticated nanostructures with enormous potential for cancer treatment. Methods and Results: The current review discu

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36

Bansal, Paramjit S., Craig L. Francis, Noel K. Hart та ін. "Regioselective Alkylation of β-Cyclodextrin". Australian Journal of Chemistry 51, № 10 (1998): 915. http://dx.doi.org/10.1071/c98064.

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Methodology for preparation of heptakis(2,6-di-O-alkyl)-β-cyclodextrins, heptakis(2-O-alkyl)-β- cyclodextrins, and heptakis(6-O-alkyl)-β-cyclodextrins in substantially purified form has been developed. Treatment of β-cyclodextrin (1) with sodium or barium hydroxide and various alkyl halides in dimethyl sulfoxide or a mixture of dimethyl sulfoxide and N,N-dimethylformamide provided the corresponding heptakis(2,6-di-O-alkyl)-β-cyclodextrins. Treatment of heptakis(6-O-t-butyldimethylsilyl)-β-cyclodextrin (5) with sodium hydroxide and several haloalkanes in dimethyl sulfoxide followed by desilylat

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37

Székely-Szentmiklósi, Blanka, and B. Tőkés. "Study of Cyclodextrin/Fluoroquinolone Inclusion Complexes by Capillary Electrophoresis." Acta Medica Marisiensis 59, no. 2 (2013): 107–10. http://dx.doi.org/10.2478/amma-2013-0026.

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AbstractIntroduction: In the present work we evaluated the complexation role of cyclodextrins toward fluoroquinolones in an attempt to assess their potential as new formulation additives for more efficient fluoroquinolone delivery and as selectors in capillary electrophoresis.Material and method: Guest-host interactions of two second generation quinolones, ciprofloxacin and norfloxacin with four cyclodextrins, beta-cyclodextrin (β-CD), gamma-cyclodextrin (γ-CD) and two beta-cyclodextrin derivatives, 2-hydroxypropyl beta-cyclodextrin (HP-β-CD) and randomly methylated beta-cyclodextrin (RAMEB),

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38

Häkkinen, Suvi, Heli Nygren, Natalia Maiorova, et al. "Biotransformation of Cyclodextrine-Complexed Semisynthetic Betulin Derivatives by Plant Cells." Planta Medica 84, no. 09/10 (2018): 743–48. http://dx.doi.org/10.1055/a-0585-6081.

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AbstractIn this study, three semisynthetic betulonic acid-based compounds, 20(29)-dihydrolup-2-en[2,3-d]isoxazol-28-oic acid, 1-betulonoylpyrrolidine, and lupa-2,20(29)-dieno[2,3-b]pyrazin-28-oic acid, were studied in biotransformation experiments using Nicotiana tabacum and Catharanthus roseus cell suspension cultures. Biotransformation was performed using cyclodextrin to aid dissolving poorly water-soluble substrates. Several new derivatives were found, consisting of oxidized and glycosylated (pentose- and hexose-conjugated) products.

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ATAV, RIZA, AYLIN YILDIZ, DERMAN VATANSEVER BAYRAMOL та AHMET ÖZGÜR AĞIRGAN. "Inclusion complexes of β-cyclodextrine with Fe3O4@HA@Ag Part I:Preparation and characterization". Industria Textila 70, № 03 (2019): 255–58. http://dx.doi.org/10.35530/it.070.03.1548.

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n this study, the preparation of inclusion complexes according to kneading and physical mixing techniques at 1:1 and 1:2 (guest:host) mass ratios of Fe 3 O 4 @HA@Ag and β-cyclodextrin were studied. Fourier transformed infrared spectroscopy, thermogravimetric analyses and scanning electron microscope analysesof the prepared complexes were carried out. According to the results obtained, it was observed Fe 3 O 4 @HA@Ag especially forms inclusion complex with β-cyclodextrin at a mass ratio of 1:2. In the second part of this study, results related to the use of these inclusion complexes during elec

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S. Panwar, Vikas, Lokesh Adhikari, Mona Semalty, and Ajay Semalty. "DRUG-CYCLODEXTRIN COMPLEXES: CURRENT STATUS AND RECENT ADVANCEMENTS." INDIAN DRUGS 60, no. 10 (2023): 7–18. http://dx.doi.org/10.53879/id.60.10.12952.

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Cyclodextrins are water-soluble oligosaccharides formed by the action of cyclodextrin glucosyl transferase enzyme (CGTase) on the medium containing starch. Cyclodextrins are proven to be a cost-effective breakthrough in the pharmaceutical industry by formulating them with polymers and drugs to improve the safety, bioavailability, and solubility of APIs. This review describes the current status and advancement of cyclodextrin research in drug delivery. The use of cyclodextrins to improve the solubility and dissolution properties of poor water-soluble products has been reviewed exhaustively with

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Matijević, Iva, Tanja Pušić та Sandra Bischof. "Isolation of α-tocopherol from cotton cosmetotextiles". Fibres and Textiles in Eastern Europe 27, № 4(136) (2019): 38–42. http://dx.doi.org/10.5604/01.3001.0013.1818.

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Cotton fabrics were treated with cosmetic substances based on α-tocopherol and cyclodextrine. Isolation of α-tocopherol from cotton cosmetotextiles was performed using three different techniques: stirring, Soxhlet and microwave extraction. High performance liquid chromatography (HPLC) was optimised and applied for the quantification of α-tocopherols in the isolates. The results revealed that all techniques are applicable for the isolation of α-tocopherol from cotton cosmetotextiles. The HPLC method proved to be the most convenient for the quantification of α-tocopherol from cotton fabrics.

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Claudy, P., P. Germain, J. M. Letoffe, A. Bayol та B. Gonzalez. "Étude thermodynamique de la réaction d'hydratation de la β-cyclodextrine". Thermochimica Acta 161, № 1 (1990): 75–84. http://dx.doi.org/10.1016/0040-6031(90)80288-a.

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Saenger, Wolfram, and Anke Müller-Fahrnow. "Cyclodextrine erhöhen die Oberflächenspannung und die kritische Micellbildungskonzentration von Detergenslösungen." Angewandte Chemie 100, no. 3 (1988): 429–31. http://dx.doi.org/10.1002/ange.19881000329.

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Anshul, Pal Deepti Modi Sunita Patidar Rajat Pawar*. "Formulation And Development of Orodispersible Tablet of Rosuvastatin Using Natural Superdisintegrant." International Journal of Pharmaceutical Sciences, no. 4 (April 17, 2025): 2141–56. https://doi.org/10.5281/zenodo.15235233.

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The present research work was to develop the preparation of orodispersible tablet of Rosuvastatin by Direct compression method using different concentration of Cassia tora seeds mucilage as natural superdisintegrants. A two-factor-three-level (32) factorial design is being used to optimize the nine formulation batches (F1-F9) were prepared accordingly. Two factors as independent variables (X1- amount of β-cyclodextrine and X2- amount of cassia tora seeds mucilage) were taken with three level (+1, 0, -1). The in-vitro drug release, Disintegration time and wetting time used as dependent var

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Castillo Cruz, Betzaida, Sandra Chinapen Barletta, Bryan G. Ortiz Muñoz, et al. "Effect of Cyclodextrins Formulated in Liposomes and Gold and Selenium Nanoparticles on siRNA Stability in Cell Culture Medium." Pharmaceuticals 17, no. 10 (2024): 1344. http://dx.doi.org/10.3390/ph17101344.

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Background: Encapsulation of siRNA fragments inside liposome vesicles has emerged as an effective method for delivering siRNAs in vitro and in vivo. However, the liposome’s fluid-phospholipid bilayer of liposomes allows siRNA fragments to diffuse out of the liposome, decreasing the dose concentration and therefore the effectiveness of the carrier. We have previously reported that β-cyclodextrins formulated in liposomes help increase the stability of siRNAs in cell culture medium. Here, we continued that study to include α, γ, methyl-β-cyclodextrins and β-cyclodextrin-modified gold and selenium

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Chesneau, Cléa, Alpha Oumar Sow, Fadila Hamachi, et al. "Cyclodextrin-Calcium Carbonate Micro- to Nano-Particles: Targeting Vaterite Form and Hydrophobic Drug Loading/Release." Pharmaceutics 15, no. 2 (2023): 653. http://dx.doi.org/10.3390/pharmaceutics15020653.

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Tailor-made and designed micro- and nanocarriers can bring significant benefits over their traditional macroscopic counterparts in drug delivery applications. For the successful loading and subsequent release of bioactive compounds, carriers should present a high loading capacity, trigger release mechanisms, biodegradability and biocompatibility. Hydrophobic drug molecules can accumulate in fat tissues, resulting in drawbacks for the patient’s recovery. To address these issues, we propose to combine the advantageous features of both host molecules (cyclodextrin) and calcium carbonate (CaCO3) p

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Prior, Marguerite, Sylvain Lehmann, Man-Sun Sy, Brendan Molloy, and Hilary E. M. McMahon. "Cyclodextrins Inhibit Replication of Scrapie Prion Protein in Cell Culture." Journal of Virology 81, no. 20 (2007): 11195–207. http://dx.doi.org/10.1128/jvi.02559-06.

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ABSTRACT Prion diseases are fatal neurodegenerative disorders that are caused by the conversion of a normal host-encoded protein, PrPC, to an abnormal, disease-causing form, PrPSc. This paper reports that cyclodextrins have the ability to reduce the pathogenic isoform of the prion protein PrPSc to undetectable levels in scrapie-infected neuroblastoma cells. Beta-cyclodextrin removed PrPSc from the cells at a concentration of 500 μM following 2 weeks of treatment. Structure activity studies revealed that antiprion activity was dependent on the size of the cyclodextrin. The half-maximal inhibito

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Li, Shujing, Li Yuan, Bing Zhang, Wei Zhou, Xinrui Wang та Dongsheng Bai. "Photostability and antioxidant activity studies on the inclusion complexes of trans-polydatin with β-cyclodextrin and derivatives". RSC Advances 8, № 46 (2018): 25941–48. http://dx.doi.org/10.1039/c8ra04778b.

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Musuc, Adina Magdalena. "Cyclodextrins: Advances in Chemistry, Toxicology, and Multifaceted Applications." Molecules 29, no. 22 (2024): 5319. http://dx.doi.org/10.3390/molecules29225319.

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Cyclodextrins (CDs) have garnered significant attention in various scientific and industrial fields due to their unique ability to form inclusion complexes with a wide range of guest molecules. This review comprehensively explores the latest advancements in cyclodextrin chemistry, focusing on the synthesis and characterization of cyclodextrin derivatives and their inclusion complexes. This review examines the biological activities of cyclodextrins, highlighting their pharmacological properties and pharmacokinetics, and discussing their promising applications in drug delivery systems. Furthermo

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Peptu, Cristian, Diana-Andreea Blaj, Mihaela Balan-Porcarasu, and Joanna Rydz. "Cyclodextrin-Oligocaprolactone Derivatives—Synthesis and Advanced Structural Characterization by MALDI Mass Spectrometry." Polymers 14, no. 7 (2022): 1436. http://dx.doi.org/10.3390/polym14071436.

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Cyclodextrins have previously been proven to be active in the catalysis of cyclic ester ring-opening reactions, hypothetically in a similar way to lipase-catalyzed reactions. However, the way they act remains unclear. Here, we focus on β-cyclodextrin’s involvement in the synthesis and characterization of β-cyclodextrin-oligocaprolactone (CDCL) products obtained via the organo-catalyzed ring-opening of ε-caprolactone. Previously, bulk or supercritical carbon dioxide polymerizations has led to inhomogeneous products. Our approach consists of solution polymerization (dimethyl sulfoxide and dimeth

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