Log in

Relevant bibliographies by topics / Cysteine biosynthesis / Dissertations / Theses

To see the other types of publications on this topic, follow the link: Cysteine biosynthesis.

Dissertations / Theses on the topic 'Cysteine biosynthesis'

Author: Grafiati

Published: 4 June 2021

Last updated: 26 July 2025

Create a spot-on reference in APA, MLA, Chicago, Harvard, and other styles

Select a source type:

Consult the top 18 dissertations / theses for your research on the topic 'Cysteine biosynthesis.'

Next to every source in the list of references, there is an 'Add to bibliography' button. Press on it, and we will generate automatically the bibliographic reference to the chosen work in the citation style you need: APA, MLA, Harvard, Chicago, Vancouver, etc.

You can also download the full text of the academic publication as pdf and read online its abstract whenever available in the metadata.

Browse dissertations / theses on a wide variety of disciplines and organise your bibliography correctly.

1

Ramos, Tania. "Cysteine biosynthesis in Leishmania." Thesis, University of Glasgow, 2014. http://theses.gla.ac.uk/5156/.

Full text

Abstract:

Every year 2 million people are diagnosed with leishmaniasis and 350 million are at risk of becoming infected. Spread throughout 88 countries in the world, leishmaniasis is a group of diseases comprising visceral, mucocutaneous and cutaneous leishmaniasis as the main forms. Visceral leishmaniasis is the most severe form of the disease and is caused by Leishmania donovani. The parasite, Leishmania, is transmitted to humans by a sandfly vector. The absence of vector-control procedures and effective vaccines for humans makes chemotherapy the only weapon against leishmaniasis. Great efforts have b

APA, Harvard, Vancouver, ISO, and other styles

2

Bawden, Christopher Simon. "Expression of microbial cysteine biosynthesis genes in sheep by transgenesis /." Title page, summary and contents only, 1991. http://web4.library.adelaide.edu.au/theses/09PH/09phb354.pdf.

Full text

APA, Harvard, Vancouver, ISO, and other styles

3

Wilcox, Donna. "The role of cathepsin L in elastin degradation." Thesis, Open University, 1990. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.277118.

Full text

APA, Harvard, Vancouver, ISO, and other styles

4

Chang, Zunxue. "Genes for cysteine biosynthesis and metabolism in Streptomyces venezuelae ISP5230, cloning, sequencing, functional analysis and relevance to chloramphenicol biosynthesis." Thesis, National Library of Canada = Bibliothèque nationale du Canada, 1999. http://www.collectionscanada.ca/obj/s4/f2/dsk1/tape7/PQDD_0018/NQ49250.pdf.

Full text

APA, Harvard, Vancouver, ISO, and other styles

5

Götz, Marion Gabriele. "Design, synthesis, and evaluation of irreversible peptidyl inhibitors for clan CA and clan CD cysteine proteases." Available online, Georgia Institute of Technology, 2004, 2004. http://etd.gatech.edu/theses/available/etd-01282004-095929/unrestricted/Gotz%5FMarionG%5F200405%5Fphd2.pdf.

Full text

Abstract:

Thesis (Ph. D.)--Chemistry and Biochemistry, Georgia Institute of Technology, 2004.<br>Dr. Suzanne Shuker, Committee Member ; Dr. Niren Murthy, Committee Member ; Dr. Donald Doyle, Committee Member ; Dr. Nicholas Hud, Committee Member ; Dr. James C. Powers, Committee Chair. Includes bibliographical references.

APA, Harvard, Vancouver, ISO, and other styles

6

Ovat, Asli. "Design, synthesis and evaluation of cysteine protease inhibitors." Diss., Georgia Institute of Technology, 2009. http://hdl.handle.net/1853/33822.

Full text

Abstract:

Cysteine proteases are important drug targets due to their involvement in many biological processes such as protein turnover, digestion, blood coagulation, apoptosis, cell differentiation, cell signaling, and the immune response. In this thesis, we have reported the design, synthesis and evaluation of clan CA and clan CD cysteine protease inhibitors. Aza-peptidyl Michael acceptor and epoxide inhibitors for asparaginyl endopeptidases (legumains) from the bloodfluke, Schistosoma mansoni (SmAE) and the hard tick, Ixodes ricinus (IrAE) were designed and synthesized. SARs were similar, but with s

APA, Harvard, Vancouver, ISO, and other styles

7

Campbell, Amy. "Design, synthesis, and evaluation of cysteine protease inhibitors." Diss., Available online, Georgia Institute of Technology, 2005, 2005. http://etd.gatech.edu/theses/available/etd-11222005-132114/.

Full text

Abstract:

Thesis (Ph. D.)--Chemistry and Biochemistry, Georgia Institute of Technology, 2006.<br>Murthy, Niren, Committee Member ; Doyle, Donald, Committee Member ; Fahrni, Christoph, Committee Member ; May, Sheldon, Committee Member ; Powers, James, Committee Chair.

APA, Harvard, Vancouver, ISO, and other styles

8

Gotz, Marion Gabriele. "Design, synthesis, and evaluation of irreversible peptidyl inhibitors for clan CA and clan CD cysteine proteases." Diss., Georgia Institute of Technology, 2004. http://hdl.handle.net/1853/8072.

Full text

Abstract:

Cysteine proteases are a class of proteolytic enzymes, which are involved in a series of metabolic and catabolic processes, such as protein turnover, digestion, blood coagulation, apoptosis, fertilization and cell differentiation, and the immune response system. The development of novel potent and selective inhibitors for cysteine proteases has therefore gained increasing attention among medicinal chemists. In this thesis we have reported the design, synthesis, and evaluation of several peptidyl inhibitors for clan CA and clan CD cysteine proteases. We have continued the investigation of dipe

APA, Harvard, Vancouver, ISO, and other styles

9

Parsot, Claude. "De l'evolution des voies de biosynthese d'acides amines." Paris 7, 1987. http://www.theses.fr/1987PA077057.

Full text

APA, Harvard, Vancouver, ISO, and other styles

10

Addy, Christine. "The biochemical and structural basis of transcription regulation by CysB protein." Thesis, University of York, 1999. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.301687.

Full text

APA, Harvard, Vancouver, ISO, and other styles

11

Williams, Roderick Adeyinka Malcolm. "Mercaptopyruvate sulfurtransferase and cysteine biosynthetic pathways in Leishmania." Thesis, University of Glasgow, 2003. http://theses.gla.ac.uk/8317/.

Full text

Abstract:

Coping with oxidative stress is vital for survival of the intracellular parasite Leishmania, but the complex biochemical mechanisms involved are not fully understood. This study focused on enzymes of cysteine metabolism in Leishmania and the parts they play. Mercaptopyruvate sulfurtransferase (EC 2.8.1.2) of Leishmania major and L. mexicana and serine acetyltransferase (EC 2.1.3.30), cysteine synthase (EC 4.2.99.8) and cystathionine b-synthase (EC 4.2.1.22) of Leishmania major have been cloned, expressed as active enzymes in Escherichia coli, and characterised. The leishmanial mercaptopyruvate

APA, Harvard, Vancouver, ISO, and other styles

12

Thulin, Elisabeth. "Mechanisms and Dynamics of Mecillinam Resistance in Escherichia coli." Doctoral thesis, Uppsala universitet, Institutionen för medicinsk biokemi och mikrobiologi, 2017. http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-330856.

Full text

Abstract:

The introduction of antibiotics in healthcare is one of the most important medical achievements with regard to reducing human morbidity and mortality. However, bacterial pathogens have acquired antibiotic resistance at an increasing rate, and due to a high prevalence of resistance to some antibiotics they can no longer be used therapeutically. The antibiotic mecillinam, which inhibits the penicillin-binding protein PBP2, however, is an exception since mecillinam resistance (MecR) prevalence has remained low. This is particularly interesting since laboratory experiments have shown that bacteria

APA, Harvard, Vancouver, ISO, and other styles

13

Rolland, Norbert. "Quelques observations sur l'O-acétylserine(thiol)lyase des plantes supérieures : localisation, structure et caractéristiques biochimiques." Grenoble 1, 1992. http://www.theses.fr/1992GRE10208.

Full text

Abstract:

Le but de ce travail consistait a caracteriser la derniere etape de la voie de biosynthese de la l-cysteine chez les plantes superieures. Cette reaction est catalysee par l'o-acetylserine(thiol) lyase (ec 4. 2. 99. 8), qui synthetise la cysteine a partir de l'o-acetylserine et du sulfure. Cette activite a ete localisee dans les plastes, les mitochondries et le cytosol des cellules de l'inflorescence de chou-fleur. A chacune de ces localisations correspond une enzyme qui differe de par sa charge globale. Ces observations sont en accord avec la necessite de synthese de la cysteine dans tous les

APA, Harvard, Vancouver, ISO, and other styles

14

Veeravalli, Karthik. "Engineering of de novo pathways for biosynthesis of glutathione analogues in Escherichia coli." Thesis, 2010. http://hdl.handle.net/2152/ETD-UT-2010-05-999.

Full text

Abstract:

The low molecular weight (L.M.W.) thiol redox couple formed by γ-L-glutamyl-L-cysteinyl glycine, also called glutathione (reduced and oxidized), is present in most eukaryotes and a few species of bacteria. Glutathione plays a role in numerous cellular processes by providing a means of shuttling electrons to different enzymatic systems. As a result, thiol-dependent redox metabolic processes are highly coupled. Due to tight coupling of redox reactions, it is difficult to understand how changes in the concentration of glutathione would affect a specific glutathione-dependent process. Interesting

APA, Harvard, Vancouver, ISO, and other styles

15

Tsai, Mu-Yu, and 蔡穆瑜. "The Biosynthesis, Tissue Distribution and Purification of Carp Ovarian Cysteine Protease." Thesis, 1997. http://ndltd.ncl.edu.tw/handle/61950978950176562493.

Full text

Abstract:

碩士<br>國立臺灣大學<br>生化科學研究所<br>85<br>In this study, a 1228bp cDNA previously isolate from a carp ovariancDNA library and encoding a 331 residue polypeptide homologous toCysteine protease was used as a probe to study its gene expression inovary. In situ hybridization showed that Cysteine protease mRNA arepresent in oocytes and follicle cells. Transcription of Cysteine proteasegene starts very early during oogensis. Antibody against the recombinantCysteine protease was used

APA, Harvard, Vancouver, ISO, and other styles

16

Tsai, Chi-Lin. "Structural and Functional Studies on Human Mitochondrial Iron-Sulfur Cluster Biosynthesis." Thesis, 2011. http://hdl.handle.net/1969.1/ETD-TAMU-2011-05-9165.

Full text

Abstract:

Iron-sulfur (Fe-S) clusters are critical protein cofactors found in all life forms. In eukaryotes, a well-conserved biosynthetic pathway located in the mitochondria is used to assemble Fe-S clusters. Although proteins required for Fe-S cluster biosynthesis have been identified, their precise function and mechanism remain elusive. In this study, biochemical and biophysical methods are applied to understand molecular details for the core components of the human Fe-S cluster biosynthesis: Nfs1, Isd11, Isu2, and frataxin (Fxn). Nfs1 is a cysteine desulfurase that converts cysteine into alanine and

APA, Harvard, Vancouver, ISO, and other styles

17

Miyyapuram, Venugopal Rao. "Synthesis and investigation of viral cysteine protease inhibitors and biosynthetic studies on subtilosin A." 2009. http://hdl.handle.net/10048/778.

Full text

Abstract:

Thesis (Ph.D.)--University of Alberta, 2009.<br>A thesis submitted to the Faculty of Graduate Studies and Research in partial fulfillment of the requirements for the degree of Doctor of Philosophy, Department of Chemistry. Title from pdf file main screen (viewed on November 8, 2009). Includes bibliographical references.

APA, Harvard, Vancouver, ISO, and other styles

18

Miyyapuram, Venugopal. "Synthesis and investigation of viral cysteine protease inhibitors and biosynthetic studies on subtilosin A." Phd thesis, 2009. http://hdl.handle.net/10048/778.

Full text

Abstract:

ABSTRACT This thesis discusses the synthesis and evaluation of cysteine protease inhibitors, the asymmetric reduction of pseudoxazolones, and the study of the mechanism of subtilosin A biosynthesis. Five classes of compounds, including pyridinylamines and ethers, have been designed with the aim of developing non-covalent inhibitors of SARSCoV 3CLpro, a chymotrypsin-like cysteine protease vital to the life cycle of the SARS coronavirus. These compounds were synthesized and screened against SARSCoV 3CLpro. 3-Bromo-5-[5-(4-nitro-phenyl)-furan-2-ylmethoxy]-pyridine (37), 5-Bromo-N-((5-(4-nitrop

APA, Harvard, Vancouver, ISO, and other styles

We offer discounts on all premium plans for authors whose works are included in thematic literature selections. Contact us to get a unique promo code!