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Journal articles on the topic 'Cystitis Cystica ET Glandularis'

Author: Grafiati

Published: 5 June 2025

Last updated: 16 July 2025

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1

Plehanova, O. A., A. G. Kochetov, A. G. Martov, B. R. Gvasalia, A. A. Gritskevich, and N. A. Baykov. "ENDOSCOPIC DIAGNOSIS OF BENIGN TUMORS OF THE BLADDER. THE FEATURES OF CLINICAL MANAGEMENT OF PATIENTS WITH CYSTITIS CYSTICA ET GLANDULARIS (CCEG) AND INTESTINAL METAPLASIA." Bulletin of the Medical Institute of Continuing Education 3, no. 1 (2023): 98–102. http://dx.doi.org/10.36107/2782-1714_2023-3-1-98-102.

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Cystitis cystica et glandularis (CCEG) and intestinal metaplasia are benign diseases indistinguishable from a bladder tumor on cystoscopy. Despite the benign nature, these pathological changes can be underlying in adenocarcinoma of the bladder. One more unsolved problem is the recurrent glandular cystitis. The article considers the modern classification of benign bladder diseases and clinical examples of recurrent cases of glandular cystitis.

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2

Bhana, Kerisha, John Lazarus, Ken Kesner, and Jeff John. "Florid cystitis cystica et glandularis causing irreversible renal injury." Therapeutic Advances in Urology 13 (January 2021): 175628722110224. http://dx.doi.org/10.1177/17562872211022465.

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Cystitis cystica et glandularis (CCEG) is widely believed to be innocuous and self-limiting. We report a case of a 32-year-old male patient who was found to have gross bilateral hydroureter and hydronephrosis and an estimated glomerular filtration rate of 3 ml/min/1.73 m2. Cystoscopy revealed extensive cystic and nodular lesions involving most of the bladder urothelium, which proved to be CCEG on histopathological analysis. Retrograde and anterograde stents could not be inserted due to obstruction of the ureters at the level of the vesicoureteric junction. Percutaneous nephrostomies were subse

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3

Bastianpillai, Christopher, Ross Warner, Luis Beltran, and James Green. "Cystitis cystica and glandularis producing large bladder masses in a 16-year-old boy." JRSM Open 9, no. 3 (2018): 205427041774606. http://dx.doi.org/10.1177/2054270417746060.

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The macroscopic appearances of florid cystitis cystica et glandularis can be mistaken for malignancy, and it is therefore important to perform a prompt resection to confirm the histological diagnosis and exclude sinister pathology.

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4

Manu, Gupta, and Kumar Singh Ashutosh. "A Retrospective Study to Determine Incidence of Adenocarcinoma Bladder in Patients with Cystitis Cystica ET Glandularis." International Journal of Pharmaceutical and Clinical Research 14, no. 7 (2022): 74–77. https://doi.org/10.5281/zenodo.13367100.

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<strong>Background:</strong> The present study was undertaken for assessing the incidence of adenocarcinoma bladder in patients with cystitis cystica et glandularis (CCG). <strong>Materials & methods:</strong> Retrospective reviewing of all the patients diagnosed with CCG was done. Record of all the patients was done in which cystoscopy and biopsy findings were available. Complete demographic and clinical details of all the patients were assessed. Total sample size was 250. On the basis of histopathological findings, patients with confirmed diagnosis of adenocarcinoma were s

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Al-Ahmadie, Hikmat, Ana M. Gomez, Nicholas Trane, and Kevin E. Bove. "Giant Botryoid Fibroepithelial Polyp of Bladder with Myofibroblastic Stroma and Cystitis Cystica et Glandularis." Pediatric and Developmental Pathology 6, no. 2 (2003): 179–81. http://dx.doi.org/10.1007/s10024-002-8817-6.

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A 3-year-old boy presented with a single episode of gross hematuria and no history of previous urinary tract disorder. Imaging studies revealed a large complex polypoid filling defect in the bladder lumen. Several attempts at transurethral biopsy and cytological examination of the urine revealed clumps of benign epithelial cells, but suspicion of a malignant neoplasm such as rhabdomyosarcoma remained high and the lesion was resected. The specimen measured 15 cm, had a narrow zone of attachment to the bladder mucosa, and was grossly botryoid. Changes typical of cystitis cystica et glandularis w

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Agrawal, Amit, Deepak Kumar, AdityaA Jha, and Puneet Aggarwal. "Incidence of adenocarcinoma bladder in patients with cystitis cystica et glandularis: A retrospective study." Indian Journal of Urology 36, no. 4 (2020): 297. http://dx.doi.org/10.4103/iju.iju_261_20.

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7

Smith, Armine Karapetian, Donna E. Hansel, and J. Stephen Jones. "Role of Cystitis Cystica et Glandularis and Intestinal Metaplasia in Development of Bladder Carcinoma." Urology 71, no. 5 (2008): 915–18. http://dx.doi.org/10.1016/j.urology.2007.11.079.

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8

Zhu, Justin X. G., Manal Y. Gabril, and Alp Sener;. "A rare case of recurrent urinary obstruction and acute renal failure from cystitis cystica et glandularis." Canadian Urological Association Journal 6, no. 2 (2012): 72–74. http://dx.doi.org/10.5489/cuaj.11033.

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9

Azhar, Azzahra, Nur Asyilla Che Jalil, Zaleha Kamaludin, et al. "Giant Botryoid Fibroepithelial Polyp of the Bladder in a 6-YearOld Girl." Malaysian Journal of Medicine and Health Sciences 20, no. 2 (2024): 385–88. https://doi.org/10.47836/mjmhs.20.2.49.

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Fibroepithelial polyps (FEPs) of the urinary tract are a rare benign tumour in the bladder. It arises from mesoderm and is mostly found in the ureter and ureteropelvic region. The authors report a case of a six-year-old girl with no history of urogenital abnormality who presented with haematuria and suprapubic pain. Ultrasound and computed tomography showed a large multilobulated mass in the urinary bladder. The resected specimen exhibited a bulbous mass with a botryoid surface. Microscopically, the polypoidal lesion is covered by reactive transitional epithelium with the presence of cystitis

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10

Potterveld, S. K., and D. Olson. "Primary Carcinoid Tumor of the Prostatic Urethra: Case Report and Review of the Literature." American Journal of Clinical Pathology 158, Supplement_1 (2022): S75. http://dx.doi.org/10.1093/ajcp/aqac126.153.

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Abstract Introduction/Objective We report a case of a 72-year-old male with a past medical history of previously treated urothelial cell carcinoma without recurrence in over ten years. Methods/Case Report Surveillance cystoscopy revealed a small lesion involving the prostatic urethra. Microscopic examination of the prostatic urethra lesion revealed a proliferation of pseudoglandular structures within the lamina propria adjacent to an area of urothelial cystitis cystica et glandularis. The pseudoglandular structures contained primarily small bland nuclei with fine chromatin and featured frequen

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11

Ni, Yongliang, and Benkang Shi. "AB057. Intravesicular administration of sodium hyaluronate ameliorates the inflammation and cell proliferation of cystitis cystica et glandularis involving interleukin-6/Stat3 signaling pathway." Translational Andrology and Urology 6, S3 (2017): AB057. http://dx.doi.org/10.21037/tau.2017.s057.

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12

Ankita, Ola Saroj, and Jaipal Shankar. "Histopathological Spectrum of Lesions in Urinary Bladder Biopsy and TURBT Specimens in Northwest Rajasthan." International Journal of Toxicological and Pharmacological Research 14, no. 3 (2024): 52–58. https://doi.org/10.5281/zenodo.10957887.

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<strong>Background</strong><strong>:</strong> Malignancies of urinary bladder or urothelial malignancies are quite common. Urothelial carcinoma account for 90% of all primary tumors of the bladder. Transitional cell carcinoma (TCC) is the commonest bladder cancer followed by squamous cell carcinoma (SCC). <strong>Methods</strong><strong>: </strong>This is a retrospective descriptive study for the period of two years from Jan 2021 to Dec 2022. All the urinary bladder specimens received in form of TURBT and cystoscopic biopsies during the study period were included. Autolysed spec

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13

Kodzo-Grey Venyo, Anthony. "Cystitis Cystica and Cystitis Glandularis of the Urinary Bladder: A Review and Update." Journal of Clinical Research and Reports 11, no. 1 (2022): 01–22. http://dx.doi.org/10.31579/2690-1919/240.

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Cystitis glandularis is a proliferative disorder of the urinary bladder which has tended to be associated with glandular metaplasia of the transitional cells that line the urinary bladder. Cystitis glandularis tends to be closely related to cystitis cystica with which it commonly does exist. Cystitis cystica represents a proliferative or reactive changes which tend to occur within von Brunn nests which do acquire luminal spaces and become cystically dilated, and cystitis may undergo glandular metaplasia which does represent cystitis glandularis or the cystitis may undergo intestinal type of me

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14

Rinaldi, Randhi, Edwin Tobing, Christiano Tansol, and Erna Kristiani. "Benign Yet Alarming: Cystitis Glandularis and Cystica with Gross Hematuria : A Case Report." Journal of Neonatal Surgery 14, no. 32S (2025): 399–402. https://doi.org/10.63682/jns.v14i32s.6888.

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Introduction: Cystitis glandularis and cystitis cystica are benign proliferative conditions of the bladder mucosa, often arising as a reactive response to chronic irritation or inflammation. While frequently asymptomatic, they can occasionally present with alarming symptoms such as gross hematuria and urinary retention, mimicking malignancy. Case Presentation: We report the case of a 43-year-old uncircumcised male who presented with acute urinary retention and gross hematuria due to intravesical blood clots. Physical examination revealed suprapubic fullness and a mildly enlarged prostate. A th

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15

Riaz, Ahsun, David D. Casalino, and Daniel P. Dalton. "Cystitis Cystica and Cystitis Glandularis Causing Ureteral Obstruction." Journal of Urology 187, no. 3 (2012): 1059–60. http://dx.doi.org/10.1016/j.juro.2011.12.021.

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16

Raja, J., K. Anson, and U. Patel. "Cystitis Cystica and Cystitis Glandularis—Presentation with Acute Ureteric Obstruction." Clinical Radiology Extra 58, no. 6 (2003): 43–44. http://dx.doi.org/10.1016/s1477-6804(03)00008-6.

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17

Güven, Eşref Oğuz, İsmail Selvi, Erdem Öztürk, et al. "Badder invasive transitional cell carsinoma, which improves from cystitis cystica and glandularis; ıs cystitis cystica and glandularis is a precancerous lesion ?" Acta Oncologica Turcica 50, no. 2 (2017): 160–64. http://dx.doi.org/10.5505/aot.2017.81300.

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18

Chang, Nai-Wen, Yu-Hui Huang, and Sung-Lang Chen. "Bladder outlet obstruction caused by cystitis cystica and glandularis at bladder neck." BMJ Case Reports 18, no. 4 (2025): e265569. https://doi.org/10.1136/bcr-2025-265569.

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Cystitis cystica and glandularis is a rare pathological condition characterised by cystic and glandular proliferations of the bladder wall. This case report presents a unique instance of bladder outlet obstruction (BOO) caused by this condition at the bladder neck, emphasising clinical manifestations, surgical intervention and postoperative outcomes. A literature review further contextualises this diagnosis within urology.

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19

Kovylina, M. V., E. A. Prilepskaya, O. A. Tsybulya, N. V. Tupikina, I. A. Reva, and T. B. Makhmudov. "Cystitis cystica and cystitis glandularis: its relationship to the development of urothelial bladder cancer." Cancer Urology 11, no. 4 (2015): 51. http://dx.doi.org/10.17650/1726-9776-2015-11-4-51-53.

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20

Waisman, Sonia S., John Banko, and William J. Cromie. "Single polypoid cystitis cystica and glandularis presenting as benign bladder tumor." Urology 36, no. 4 (1990): 364–66. http://dx.doi.org/10.1016/0090-4295(90)80250-q.

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21

Dhall, Deepti, Hikmat Al-Ahmadie, and Semra Olgac. "Nested Variant of Urothelial Carcinoma." Archives of Pathology & Laboratory Medicine 131, no. 11 (2007): 1725–27. http://dx.doi.org/10.5858/2007-131-1725-nvouc.

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Abstract Nested variant of urothelial carcinoma is a rare neoplasm that is histologically characterized by large numbers of small, closely packed, haphazardly arranged, poorly defined, confluent irregular nests of bland-appearing urothelial cells infiltrating the lamina propria and the muscularis propria. Due to the cells' deceptively bland appearance, the tumors are sometimes misdiagnosed as benign lesions, leading in some cases to a significant delay in establishing the correct diagnosis and thus contributing to this neoplasm's advanced stage. Nested variant of urothelial carcinoma must be d

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22

GORDON, NEIL S. I., ROGER A. SINCLAIR, and ROSS M. SNOW. "PELVIC LIPOMATOSIS WITH CYSTITIS CYSTICA, CYSTITIS GLANDULARIS AND ADENOCARCINOMA OF THE BLADDER: FIRST REPORTED CASE." Australian and New Zealand Journal of Surgery 60, no. 3 (1990): 229–32. http://dx.doi.org/10.1111/ans.1990.60.3.229.

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23

Nowels, K., E. Kent, K. Rinsho, and R. Oyasu. "Prostate Specific Antigen and Acid Phosphatase-Reactive Cells in Cystitis Cystica and Glandularis." Journal of Urology 141, no. 4 (1989): 1061. http://dx.doi.org/10.1016/s0022-5347(17)41170-0.

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24

Diataga Sylvestre, YONLI, Thomas Tabourin, Mohamed Arezki Lafifi, et al. "A Long-Term Follow-Up of Cystitis Cystica and Glandularis: Two Case Reports." Archives of Urology 6, no. 1 (2024): 18–21. http://dx.doi.org/10.22259/2638-5228.0601003.

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25

Jangir, Babu Lal, and Ramesh Somvanshi. "Pathological studies on spontaneous urinary bladder lesions in Indian buffaloes." Buffalo Bulletin 42, no. 2 (2023): 277. http://dx.doi.org/10.56825/bufbu.2023.4223585.

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The present investigation describes the spontaneous pathological lesions in urinary bladders (n = 177) of slaughtered buffaloes collected from Northern India. Gross examination revealed congestion, haemorrhages, oedematous changes and thickening of mucosa. Microscopically, epithelial abnormalities, inflammatory and neoplastic conditions were noticed. Epithelial abnormalities included epithelial hyperplasia, von Brunn’s nests, cystitis cystica and cystitis glandularis. Inflammatory conditions such as congestion, haemorrhages and cystitis were noticed. Cystitis was classified as lymphocytic, pla

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26

Swathi, Dr Kantipudi Sree, Dr Shraddha Prabha, and Dr Geeta Kiran A. "An Incidental Finding Of A Tumour In A Case Of Pityriasis Rubra Pilaris- A Case Report." IOSR Journal of Dental and Medical Sciences 23, no. 11 (2024): 33–37. http://dx.doi.org/10.9790/0853-2311013337.

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We report a 49-year-old man who had a progressive rash that covered 90% of his total surface area in a period of 5 years. Confluent scaly erythematous plaques, which started on the upper back and spread to involve the scalp, face, chest, and limbs. Notable observations were subungual hyperkeratosis and onychogryphosis in all nails, along with follicular keratotic papules with waxy keratoderma on the palms and soles. Biopsy from skin lesions were suggestive of PRP. A focal hypoechoic thickening at the base of the bladder was found during abdominal ultrasonography, which could indicate edema or

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27

Manini, Claudia, Javier C. Angulo, and José I. López. "Mimickers of Urothelial Carcinoma and the Approach to Differential Diagnosis." Clinics and Practice 11, no. 1 (2021): 110–23. http://dx.doi.org/10.3390/clinpract11010017.

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A broad spectrum of lesions, including hyperplastic, metaplastic, inflammatory, infectious, and reactive, may mimic cancer all along the urinary tract. This narrative collects most of them from a clinical and pathologic perspective, offering urologists and general pathologists their most salient definitory features. Together with classical, well-known, entities such as urothelial papillomas (conventional (UP) and inverted (IUP)), nephrogenic adenoma (NA), polypoid cystitis (PC), fibroepithelial polyp (FP), prostatic-type polyp (PP), verumontanum cyst (VC), xanthogranulomatous inflammation (XI)

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Nath, Vikas, and Mithra Baliga. "Urinary Bladder Adenocarcinoma Metastatic to the Abdominal Wall: Report of a Case with Cytohistologic Correlation." Case Reports in Pathology 2016 (2016): 1–6. http://dx.doi.org/10.1155/2016/8608412.

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We report a case of adenocarcinoma metastatic to the abdominal wall in a 71-year-old man with a history of primary bladder adenocarcinoma. CT-guided core biopsy was performed; imprints and histologic sections showed malignant glands lined by tumor cells with hyperchromatic nuclei and prominent nucleoli, infiltrating through skeletal muscle. Immunohistochemistry revealed positivity for CK7, membranous/cytoplasmicβ-catenin, caudal-type homeobox transcription factor 2 (CDX2), andα-methylacyl coenzyme A racemase and negativity for CK20, p63, prostate-specific antigen (PSA), and prostate-specific a

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29

Zhong, Minghao, Elizabeth Gersbach, Stephen M. Rohan, and Ximing J. Yang. "Primary Adenocarcinoma of the Urinary Bladder: Differential Diagnosis and Clinical Relevance." Archives of Pathology & Laboratory Medicine 137, no. 3 (2013): 371–81. http://dx.doi.org/10.5858/arpa.2012-0076-ra.

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Context.—Glandular lesions of the urinary bladder include a broad spectrum of entities ranging from completely benign glandular lesions to primary and secondary malignancies. Common benign bladder lesions that exhibit glandular differentiation include cystitis cystica, cystitis glandularis, von Brunn nests, nephrogenic adenoma, intestinal metaplasia, urachal remnant, endometriosis, and prostatic-type polyp. The World Health Organization defines primary adenocarcinoma of the bladder as an epithelial malignancy with pure glandular differentiation without evidence of typical urothelial carcinoma.

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30

Venyo, Anthony Kodzo-Grey. "Microcystic Variant of Urothelial Carcinoma." Advances in Urology 2013 (2013): 1–7. http://dx.doi.org/10.1155/2013/654751.

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Background. Microcystic variant of urothelial carcinoma is one of the new variants of urothelial carcinoma that was added to the WHO classification in 2004.Aims.To review the literature on microcystic variant of urothelial carcinoma.Methods.Various internet search engines were used to identify reported cases of the tumour.Results. Microscopic features of the tumour include: (i) Conspicuous intracellular and intercellular lumina/microcysts encompassed by malignant urothelial or squamous cells. (ii) The lumina are usually empty; may contain granular eosinophilic debris, mucin, or necrotic cells.

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31

Abasher, Abdelazim, Ali Abdel Raheem, Rakan Aldarrab, Mohammed Aldurayhim, Azza Attallah, and Omaya Banihani. "Bladder outlet obstruction secondary to posterior urethral cystitis cystica & glandularis in a 12-year-old boy. A rare case scenario." Urology Case Reports 33 (November 2020): 101425. http://dx.doi.org/10.1016/j.eucr.2020.101425.

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32

Masuoka, Sota, Osamu Miyazaki, Ayako Imai, et al. "“Another inchworm sign” on dynamic contrast-enhanced magnetic resonance imaging in pediatric patients with cystitis cystica and glandularis: Radiologic-pathologic correlation." Radiology Case Reports 18, no. 3 (2023): 840–43. http://dx.doi.org/10.1016/j.radcr.2022.11.069.

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33

Harik, Lara Rabih, and Kathleen Mary O'Toole. "Nonneoplastic Lesions of the Prostate and Bladder." Archives of Pathology & Laboratory Medicine 136, no. 7 (2012): 721–34. http://dx.doi.org/10.5858/arpa.2011-0584-ra.

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Context.—Specimens from the prostate and bladder are commonly encountered by the general surgical pathologist. Emphasis is usually placed on neoplasms of the bladder and prostate, particularly if malignant, owing to their therapeutic consequences. A good command of benign lesions occurring in the bladder and prostate, and knowledge of their preneoplastic potential will help pathologists confidently diagnose malignancy versus its benign mimickers and guide the urologists in choosing the appropriate therapy and follow-up for the patient. Objective.—To present a mixture of benign entities, and di

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34

Garg, Harshit, Prabhjot Singh, Brusabhanu Nayak, et al. "Understanding an unusual urothelial disorder: cystitis cystica et glandularis." Journal of Clinical Urology, August 2, 2021, 205141582110328. http://dx.doi.org/10.1177/20514158211032819.

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Objectives: To study the presentation and natural course of cystitis cystica et glandularis. Methods: A retrospective analysis of patients with histopathologically confirmed cystitis cystica et glandularis from March 2016 to March 2018 who at least completed their 2 years’ follow-up was performed. Perioperative details along with the last available follow-up were included in the analysis. Results: A total of 10 patients were included. The mean age (± standard deviation) was 33.4 (±14.0) years and nine (90%) were men. The most common presentation was storage and voiding lower urinary tract symp

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35

Son, Young, Ian Madison, Julia Scali, Paul Chialastri, and Gordon Brown. "Cystitis Cystica Et Glandularis Causing Lower Urinary Tract Symptoms in a 29-Year-Old Male." Cureus, August 13, 2021. http://dx.doi.org/10.7759/cureus.17144.

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36

Zhu, Justin X. G., Manal Y. Gabril, and Alp Sener. "A rare case of recurrent urinary obstruction and acute renal failure from cystitis cystica et glandularis." Canadian Urological Association Journal 6, no. 2 (2012). http://dx.doi.org/10.5489/cuaj.164.

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The use of lasers to perform photoselective vaporization of the prostate (PVP) has been widely accepted as a safe and effectivetreatment for benign prostatic hyperplasia with very few reported complications. To date, most of the published data report outcomesfor the 80-W potassium-titanyl-phosphate laser. A more potent laser, the 120-W GreenLight HPS, was introduced in 2006 and provides more efficient vaporization of prostatic tissue anddecreased operating times. Despite these benefits, the increased energy applied to the prostate evokes concerns of potential serious complications, including c

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37

Demirer, Zafer. "A Rare Case of Bilaterale Ureterohydronephrosis due to Cystitis Cystica Et Glandularis and Review of the Literature." Clinical Medical Reviews and Case Reports 2, no. 10 (2015). http://dx.doi.org/10.23937/2378-3656/1410061.

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Popov, Hristo, George S. Stoyanov, and Peter Ghenev. "Intestinal-Type Adenocarcinoma of the Urinary Bladder With Coexisting Cystitis Cystica et Glandularis and Intestinal Metaplasia: A Histopathological Case Report." Cureus, March 22, 2023. http://dx.doi.org/10.7759/cureus.36554.

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39

Ni, Yongliang, Shaohua Zhao, Xiaoxuan Yin, et al. "Intravesicular administration of sodium hyaluronate ameliorates the inflammation and cell proliferation of cystitis cystica et glandularis involving interleukin-6/JAK2/Stat3 signaling pathway." Scientific Reports 7, no. 1 (2017). http://dx.doi.org/10.1038/s41598-017-16088-9.

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40

Jakus, Dora, Ivan Jurić, and Marijan Šitum. "Benign urinary bladder masses: rare entities." African Journal of Urology 29, no. 1 (2023). http://dx.doi.org/10.1186/s12301-023-00382-2.

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Abstract Background This study aimed to present the characteristics and outcomes of benign urinary bladder masses, as well as the characteristics of the patients diagnosed with such lesions. Methods A single-center, cross-sectional, retrospective study was conducted. The study involved patients who underwent transurethral resection of the primary bladder tumor over a four-year period (May 2017–2021) and were subsequently diagnosed with a benign bladder lesion. Results Out of 478 patients who underwent transurethral resection of the primary bladder tumor, 26 (5.4%) were diagnosed with a benign

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