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Journal articles on the topic 'Cytogenetic Variation'

Author: Grafiati

Published: 5 June 2025

Last updated: 1 August 2025

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1

Atli, Emine, Hakan Gurkan, Engin Atli, et al. "THE IMPORTANCE OF TARGETED NEXT-GENERATION SEQUENCING USAGE IN CYTOGENETICALLY NORMAL MYELOID MALIGNANCIES." Mediterranean Journal of Hematology and Infectious Diseases 13, no. 1 (2020): e2021013. http://dx.doi.org/10.4084/mjhid.2021.013.

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Advanced diagnostic methods give an advantage for the identification of the abnormalities in myeloid malignancies. Various researchers have shown the potential importance of genetic tests both before the onset of the disease and during the remission. Large testing panels prevents false negative results in myeloid malignancies. But the important question is how the results of conventional cytogenetic and molecular cytogenetic techniques can be merged together with NGS technologies. In this paper, we drew an algorithm for evaluation of the myeloid malignancies. In order to evaluate genetic abnor

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ABDULAZIZ, ABDUJABAR, and KIFLE DAGNE Dr. "A REVIEW ON CYTOGENETICAL STATUS OF PLANT-PARASITIC ROOTKNOT NEMATODE (Meloidogyne spp)." International Journal of Recent Research in Life Sciences 9, no. 2 (2022): 35–45. https://doi.org/10.5281/zenodo.6524808.

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<strong>Abstracts: </strong>Root‐knot nematodes (RKN), (<em>Meloidogyne</em> spp.) are obligate endoparasites of more than 3000 species of plants, which results in $80 billion worth of economic loss every year, worldwide. Considerable variation in ability to break crop resistance and to reproduce on different crop species is observed both between and within <em>Meloidogyne</em>. The main feature of plant-parasitic root-knot nematode is its potential host range encompassing more than 3,000 plant species. The adaptation of root-knot nematodes to its various environments of plant hosts

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Campbell, Lynda J., Stephen J. Farish, and Joanne S. White. "Seasonal Variation in New Adult Acute Myeloid Leukemia." Blood 104, no. 11 (2004): 3017. http://dx.doi.org/10.1182/blood.v104.11.3017.3017.

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Abstract Investigations into seasonal trends for the onset of leukemia have produced conflicting results. The majority of studies demonstrating seasonal variation have done so for childhood ALL and have suggested a role for an infectious agent. Few investigations have studied adult AML and none have looked at the potential differences between various AML subtypes. An infectious etiology for adult AML will more likely be reflected by cases that are truly de novo and that have not arisen by transformation from a pre-leukemic phase or from prior exposure to a carcinogenic agent. The Victorian Can

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4

Li, Ruzhong, David M. Stelly, and Norma L. Trolinder. "Cytogenetic abnormalities in cotton (Gossypium hirsutum L.) cell cultures." Genome 32, no. 6 (1989): 1128–34. http://dx.doi.org/10.1139/g89-566.

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High frequencies of somaclonal phenotypic and cytogenetic variation have been observed previously among regenerants from cotton (Gossypium hirsutum L., 2n = 4x = 52). In this study we endeavored to determine if cytogenetic abnormalities would be detectable in cotton cell cultures and if so, whether or not the observed abnormalities would parallel those expected on the basis of previous cytogenetic analyses of cotton somaclones. Paired samples from suspension cultures established from 21-month-old 'Coker 312' and 8-month-old 'Coker 315' calli were pretreated or not pretreated with colchicine to

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5

Linacero, R., and A. M. Vazquez. "Cytogenetic variation in rye regenerated plants and their progeny." Genome 35, no. 3 (1992): 428–30. http://dx.doi.org/10.1139/g92-063.

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Regenerated plants obtained from immature embryo-derived calluses of four cultivars of rye, as well as their progeny, were cytologically analyzed. Chromosome number modified plants were found among the regenerants. The progeny of apparently normal diploid regenerated plants was tested and in some cases chromosomally abnormal plants appeared. Equally, meiotic abnormalities were observed in some of the regenerated plants and their progenies. The cytological variations observed were inheritable and in some cases both types of abnormalities could be related. The nature of the variations is discuss

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Akkari, Yassmine M. N., Linda B. Baughn, Adrian M. Dubuc, et al. "Guiding the global evolution of cytogenetic testing for hematologic malignancies." Blood 139, no. 15 (2022): 2273–84. http://dx.doi.org/10.1182/blood.2021014309.

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Abstract Cytogenetics has long represented a critical component in the clinical evaluation of hematologic malignancies. Chromosome banding studies provide a simultaneous snapshot of genome-wide copy number and structural variation, which have been shown to drive tumorigenesis, define diseases, and guide treatment. Technological innovations in sequencing have ushered in our present-day clinical genomics era. With recent publications highlighting novel sequencing technologies as alternatives to conventional cytogenetic approaches, we, an international consortium of laboratory geneticists, pathol

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Spies, J. J., and G. E. Gibbs Russell. "Variation in important pasture grasses. II. Cytogenetic and reproductive variation." Journal of the Grassland Society of Southern Africa 5, no. 1 (1988): 22–25. http://dx.doi.org/10.1080/02566702.1988.9648104.

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8

Frana, Vitor André, Weferson Júnio da Graça, Éder André Gubiani, Jocicléia Thums Konerat, and Vladimir Pavan Margarido. "Evidence of the color pattern variation in populations of Gymnotus pantanal (Gymnotiformes) from three streams in the upper Paraná River basin, Brazil." Neotropical Ichthyology 9, no. 2 (2011): 343–50. http://dx.doi.org/10.1590/s1679-62252011005000013.

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Color pattern is an important character in the systematics and alpha-taxonomy of electric fishes of the genus Gymnotus. This paper presents evidence of color variation in populations of G. pantanal found in the streams Jacutinga and Pinheirinho, in the upper Paraná River basin, southern Brazil. Color variations were corroborated for morphological and cytogenetic data. Our results show the importance of integrating morphologic and cytogenetic data in the taxonomy of the Gymnotus species.

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GARCIA, L., M. PONSÀ, J. EGOZCUE, and M. GARCIA. "Cytogenetic variation in Ctenomys perrensi (Rodentia, Octodontidae)." Biological Journal of the Linnean Society 71, no. 4 (2000): 615–24. http://dx.doi.org/10.1111/j.1095-8312.2000.tb01281.x.

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10

Fouroutan, Parisa, Masoud Sheidai, and Fahimeh Koohdar. "The role of chromosomal rearrangements, polyploidy, and genome size variation in the diversity and ecological distribution of Asparagus L. species: a landscape cytogenetics meta-analysis approach." Caryologia 77, no. 2 (2024): 3–18. https://doi.org/10.36253/caryologia-2672.

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The Asparagus genus includes a group of plants with economic and medicinal importance. Although numerous cytogenetic and genetic studies have been conducted on Asparagus species, there are no reports on landscape genetics, landscape cytogenetics, or Asparagus cultivation in response to climate change. Therefore, we designed this study to answer the above-mentioned objectives. We performed a meta-analysis involving landscape genetic studies based on available cytogenetic data and reported DNA C-values for several Asparagus species from different countries. Additionally, species distribution mod

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Roa, Fernando, and Mariana Pires de Campos Telles. "The Cerrado (Brazil) plant cytogenetics database." Comparative Cytogenetics 11, no. 2 (2017): 285–97. http://dx.doi.org/10.3897/compcytogen.11(2).11395.

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Cerrado is a biodiversity hotspot that has lost ca. 50% of its original vegetation cover and hosts ca. 11,000 species belonging to 1,423 genera of phanerogams. For a fraction of those species some cytogenetic characteristics like chromosome numbers and C-value were available in databases, while other valuable information such as karyotype formula and banding patterns are missing. In order to integrate and share all cytogenetic information published for Cerrado species, including frequency of cytogenetic attributes and scientometrics aspects, Cerrado plant species were searched in bibliographic

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Roa, Fernando, and Mariana Pires de Campos Telles. "The Cerrado (Brazil) plant cytogenetics database." Comparative Cytogenetics 11, no. (2) (2017): 285–97. https://doi.org/10.3897/CompCytogen.v11i2.11395.

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Cerrado is a biodiversity hotspot that has lost ca. 50% of its original vegetation cover and hosts ca. 11,000 species belonging to 1,423 genera of phanerogams. For a fraction of those species some cytogenetic characteristics like chromosome numbers and C-value were available in databases, while other valuable information such as karyotype formula and banding patterns are missing. In order to integrate and share all cytogenetic information published for Cerrado species, including frequency of cytogenetic attributes and scientometrics aspects, Cerrado plant species were searched in bibliographic

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Mayr, B., B. Bockstahler, G. Loupal, M. Reifinger, and W. Schleger. "Cytogenetic variation between four cases of feline fibrosarcoma." Research in Veterinary Science 61, no. 3 (1996): 268–70. http://dx.doi.org/10.1016/s0034-5288(96)90076-4.

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Aldrich, Melinda C., Luoping Zhang, Joseph L. Wiemels, et al. "Cytogenetics of Hispanics and Whites with Childhood Acute Lymphoblastic Leukemia in California." Blood 106, no. 11 (2005): 4536. http://dx.doi.org/10.1182/blood.v106.11.4536.4536.

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Abstract Epidemiologic studies of childhood leukemia have made limited use of tumor genetic characteristics, which may be related to disease etiology. We characterized the cytogenetics of 543 childhood leukemia patients (0–14 years of age) enrolled in the Northern California Childhood Leukemia Study, an approximately population-based study comprised primarily of Hispanics (42%) and non-Hispanic whites (41%), and compared the cytogenetic profiles between these two ethnic groups. Subjects were classified by immunophenotypes, conventional cytogenetic characteristics, and fluorescence in situ hybr

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Araújo, Naiara Pereira, Cibele Bonvicino, and Marta Svartman. "Comparative cytogenetics of four species of Thrichomys (Rodentia: Echimyidae)." Genome 62, no. 1 (2019): 31–41. http://dx.doi.org/10.1139/gen-2018-0147.

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Thrichomys Trouessart, 1880 is a genus of echimyid rodents endemic to South America, distributed from northeastern Brazil to Paraguay and Bolivia. Although all the recognized species of this genus have already been karyotyped, detailed comparative cytogenetic analyses have not been performed yet. We karyologically analyzed four species of Thrichomys from different Brazilian states. Our analyses included GTG- and CBG-banding, silver-staining of the nucleolar organizer regions (Ag-NORs), and fluorescent in situ hybridization (FISH) with telomeric and 45S rDNA probes. Comparative GTG-banding sugg

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Augustin, Lizete, Luiz Carlos Federizzi, and Maria Jane Cruz de Melo Sereno. "Agronomic, cytogenetic, and isoenzymatic characterizations of oat somaclones." Genetics and Molecular Biology 23, no. 3 (2000): 649–60. http://dx.doi.org/10.1590/s1415-47572000000300025.

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Immature embryo-derived somaclones regenerated from genotypes UPF 12, UPF 89S080 and UFRGS 7 were analyzed for eight agronomic traits and two enzymatic systems in order to evaluate the potential of tissue cultures to induce genetic variability in oats (Avena sativa L.). Some somaclones were also analyzed cytogenetically. Agronomic traits were evaluated in the field for all somaclones in 1993 and 1994. Bi-directional variation (P < 0.05) was detected for all characteristics, and the average frequency of variation observed in 1993 in somaclones from genotypes UPF 12 and UPF 89S080 was 35.2%.

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Parise-Maltempi, PP, and RMP Avancini. "Comparative cytogenetic study in Muscidae flies." Brazilian Journal of Biology 67, no. 4 suppl (2007): 945–50. http://dx.doi.org/10.1590/s1519-69842007000500020.

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The chromosome modal number in Muscoidea Diptera is 2n = 12, including five pairs of autosomes and one sex chromosome pair. Nevertheless, some species with 2n = 10 chromosomes have been described, all of them from the Muscidae family. We analyzed the karyotype of some Muscidae species from different subfamilies and compared the obtained data with the karyotypes of some species of the families Calliphoridae and Sarcophagidae. Comparisons of these species with other Muscidae species revealed a considerable variation among their sex chromosomes. This variation in the length of the sex chromosomes

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18

Peniton, Elizar Alumbro Jr. "A Review on the Cytogenetic Integrity of Micropropagated Plants." Philippine Agricultural Scientist 108, no. 2 (2025): 186–204. https://doi.org/10.62550/cr1401524.

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Cytogenetic stability is essential for the survival of micropropagated plants. While micropropagation allows rapid propagation of plants with desirable phenotypes, it may also produce genetic variations that are, at times, cytogenetically observable. Factors affecting these variations are not fully understood, and micropropagation protocols are optimized to produce genetically stable regenerants. The genetic stability of micropropagated plants is traditionally assessed by comparing the phenomorphological traits of the regenerants to the mother plant. However, genetic variation does not often r

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19

Mayr, B., M. Jugl, G. Brem, M. Reifinger, and G. Loupal. "Cytogenetic Variation in Six Cases of Feline Mammary Tumours." Journal of Veterinary Medicine Series A 46, no. 6 (1999): 367–77. http://dx.doi.org/10.1046/j.1439-0442.1999.00228.x.

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20

Calleros, L., F. Panzera, M. D. Bargues, et al. "Systematics of Mepraia (Hemiptera-Reduviidae): Cytogenetic and molecular variation." Infection, Genetics and Evolution 10, no. 2 (2010): 221–28. http://dx.doi.org/10.1016/j.meegid.2009.12.002.

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21

Karkera, Amritha C., Jennifer Laffin, and Ronald S. Go. "Utility of Routine Bone Marrow Fluorescent in Situ Hybridization (FISH) Panel Testing in Patients Suspected of Myelodysplastic Syndrome (MDS): An Analysis of 3,418 Patients and Comparison of Academic Versus Community Practices." Blood 120, no. 21 (2012): 3855. http://dx.doi.org/10.1182/blood.v120.21.3855.3855.

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Abstract Abstract 3855 Background: Metaphase cytogenetics and FISH panel testing are commonly performed on bone marrow aspirate samples from patients suspected of having MDS. We performed this study to determine the frequency of simultaneous testing in academic versus community practices and whether routine FISH panel provides additional information to metaphase cytogenetics. Methods: After approval from our institutional review boards, a list of patients who had bone marrow aspirate samples submitted to the Wisconsin State Laboratory of Hygiene between January 2000 to June 2011, with a diagno

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22

Stelly, David M., D. W. Altman, R. J. Kohel, T. S. Rangan, and E. Commiskey. "Cytogenetic abnormalities of cotton somaclones from callus cultures." Genome 32, no. 5 (1989): 762–70. http://dx.doi.org/10.1139/g89-509.

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Somaclonal variation occurs among regenerants from tissue culture of many plant species. Our objective was to determine whether cytogenetic variation contributes to somaclonal variation in cotton (Gossyptum hirsutum L.,2n = 4x = 52). Of 117 somaclones of cotton regenerated from 18-month-old callus cultures of 'SJ-2' and 'SJ-5' cultivars, 35 were analyzed for meiotic abnormalities. The population of somaclones was extremely varied in phenotype, most plants being strikingly aberrant in phenotype. Fertility was generally poor: 84% failed to set bolls and only 5% set 10 or more bolls in a field en

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23

Gill, B. S., L. N. W. Kam-Morgan, and J. F. Shepard. "Cytogenetic and phenotypic variation in mesophyll cell-derived tetraploid potatoes." Journal of Heredity 78, no. 1 (1987): 15–20. http://dx.doi.org/10.1093/oxfordjournals.jhered.a110298.

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24

Nagy, Szabolcs, Péter J. Polgár, Magnus Andersson, and András Kovács. "Quick cytogenetic screening of breeding bulls using flow cytometric sperm DNA histogram analysis." Acta Veterinaria Hungarica 64, no. 3 (2016): 372–79. http://dx.doi.org/10.1556/004.2016.035.

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The aim of the present study was to test the FXCycle PI/RNase kit for routine DNA analyses in order to detect breeding bulls and/or insemination doses carrying cytogenetic aberrations. In a series of experiments we first established basic DNA histogram parameters of cytogenetically healthy breeding bulls by measuring the intraspecific genome size variation of three animals, then we compared the histogram profiles of bulls carrying cytogenetic defects to the baseline values. With the exception of one case the test was able to identify bulls with cytogenetic defects. Therefore, we conclude that

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Moscone, Eduardo A., Franz Klein, Maria Lambrou, Jörg Fuchs, and Dieter Schweizer. "Quantitative karyotyping and dual-color FISH mapping of 5S and 18S-25S rDNA probes in the cultivated Phaseolus species (Leguminosae)." Genome 42, no. 6 (1999): 1224–33. http://dx.doi.org/10.1139/g99-070.

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Double-color fluorescence in situ hybridization (FISH) followed by DAPI counterstaining allowed the chromosomal assignment of 5S and 18S-25S rRNA genes in the four cultivated Phaseolus species; P. vulgaris, P. coccineus, P. acutifolius, and P. lunatus (all: 2n = 2x = 22). The rRNA gene loci display variation between species as reflected in differences of signal size and (or) number. From one to three pairs of 5S sites and one to seven pairs of 18S-25S sites were found in the diploid complements of the four taxa studied. Intraspecific variation was studied in P. vulgaris, and it is shown that t

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Geise, Lena, Luciana Guedes Pereira, Marianne Bello, and Marcia Aguieiras. "Cytogenetic diversity of non-volant small mammals in the Serra dos Órgãos region, Rio de Janeiro state, Brazil." Therya 16, no. 1 (2025): 17–27. https://doi.org/10.12933/therya-25-6142.

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The Atlantic Forest is one of South America's most biodiverse regions, hosting a significant portion of Brazil's small non-volant mammal diversity, including 267 rodent and 66 marsupial species. The Serra dos Órgãos region in Rio de Janeiro state is a key area for studying this diversity, as it houses 32 rodent and 13 marsupial species. Rodents, unlike marsupials, exhibit a high diversity of chromosomal forms, which serve as important taxonomic tools for identifying cryptic species. Our study used cytogenetic analyses to enhance the taxonomic resolution and understanding of small mammal biodiv

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Shapoval, Nazar A., and Vladimir A. Lukhtanov. "Intragenomic variations of multicopy ITS2 marker in Agrodiaetus blue butterflies (Lepidoptera, Lycaenidae)." Comparative Cytogenetics 9, no. (4) (2015): 483–97. https://doi.org/10.3897/CompCytogen.v9i4.5429.

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The eukaryotic ribosomal DNA cluster consists of multiple copies of three genes, 18S, 5. 8S and 28S rRNAs, separated by multiple copies of two internal transcribed spacers, ITS1 and ITS2. It is an important, frequently used marker in both molecular cytogenetic and molecular phylogenetic studies. Despite this, little is known about intragenomic variations within the copies of eukaryotic ribosomal DNA genes and spacers. Here we present data on intraindividual variations of ITS2 spacer in three species of Agrodiaetus Hübner, 1822 blue butterflies revealed by cloning technique. We demonstrate that

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Shibata, Fukashi, Masahiro Hizume, and Yuzo Kuroki. "Molecular cytogenetic analysis of supernumerary heterochromatic segments in Rumex acetosa." Genome 43, no. 2 (2000): 391–97. http://dx.doi.org/10.1139/g99-128.

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The dioecious plant Rumex acetosa shows intraspecific karyotype variation, caused by supernumerary heterochromatic segments or DAPI (4',6-diamidino-2 phenylindole)-bands at the ends of the short arms of three pairs of autosomes. A DNA sequence (RAE730) specific to the supernumerary heterochromatic segments was cloned and sequenced. RAE730 was about 730 bp and AT-rich (71% AT-content). Using fluorescence in situ hybridization (FISH), RAE730 was localized in the supernumerary DAPI-positive heterochromatic segments on several mitotic chromosomes and chromocenters in interphase nuclei, but not in

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Kretschmer, Rafael, Ricardo José Gunski, Analía del Valle Garnero, et al. "Chromosomal Analysis in Crotophaga ani (Aves, Cuculiformes) Reveals Extensive Genomic Reorganization and an Unusual Z-Autosome Robertsonian Translocation." Cells 10, no. 1 (2020): 4. http://dx.doi.org/10.3390/cells10010004.

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Although cytogenetics studies in cuckoos (Aves, Cuculiformes) have demonstrated an interesting karyotype variation, such as variations in the chromosome morphology and diploid number, their chromosome organization and evolution, and relation with other birds are poorly understood. Hence, we combined conventional and molecular cytogenetic approaches to investigate chromosome homologies between chicken and the smooth-billed ani (Crotophaga ani). Our results demonstrate extensive chromosome reorganization in C. ani, with interchromosomal rearrangements involving macro and microchromosomes. Intrac

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Degrandi, Tiago M., Suziane A. Barcellos, Alice L. Costa, Analía D. V. Garnero, Iris Hass, and Ricardo J. Gunski. "Introducing the Bird Chromosome Database: An Overview of Cytogenetic Studies in Birds." Cytogenetic and Genome Research 160, no. 4 (2020): 199–205. http://dx.doi.org/10.1159/000507768.

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Bird chromosomes, which have been investigated scientifically for more than a century, present a number of unique features. In general, bird karyotypes have a high diploid number (2n) of typically around 80 chromosomes that are divided into macro- and microchromosomes. In recent decades, FISH studies using whole chromosome painting probes have shown that the macrochromosomes evolved through both inter- and intrachromosomal rearrangements. However, chromosome painting data are available for only a few bird species, which hinders a more systematic approach to the understanding of the evolutionar

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Kuznetsova, Valentina, Snejana Grozeva, Seppo Nokkala, and Christina Nokkala. "Cytogenetics of the true bug infraorder Cimicomorpha (Hemiptera, Heteroptera): a review." ZooKeys 154 (December 12, 2011): 31–70. https://doi.org/10.3897/zookeys.154.1953.

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The Cimicomorpha is one of the largest and highly diversified infraorders of the Heteroptera. This group is also highly diversified cytogenetically and demonstrates a number of unusual cytogenetic characters such as holokinetic chromosomes; m-chromosomes; multiple sex chromosome systems; post-reduction of sex chromosomes in meiosis; variation in the presence/absence of chiasmata in spermatogenesis; different types of achiasmate meiosis. We present here a review of essential cytogenetic characters of the Cimicomorpha and outline the chief objectives and goals of future investigations in the fie

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Zhang, Tao, Paul Auer, Stephen R. Spellman, Jing Dong, Wael Saber, and Yung-Tsi Bolon. "CYTO-SV-ML: A Machine Learning Tool for Cytogenetic Structural Variant Analysis in Somatic Cell Type Using Genome Sequences." Life 15, no. 6 (2025): 929. https://doi.org/10.3390/life15060929.

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(1) Background: Although whole genome sequencing (WGS) has enabled the comprehensive analyses of structural variants (SVs), more accurate and efficient methods are needed to distinguish large somatic SVs (SV size ≥ 1 Mb) traditionally detected through cytogenetic testing from germline SVs. (2) Methods: A customized machine learning pipeline (CYTO-SV-ML) under Snakemake automation workflow was developed with a user interface to identify somatic cytogenetic SVs in WGS data. And this tool was applied for characterizing structural variation profiles in the whole blood of patients with myelodysplas

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Albitar, Maher, Andrew Ip, Andre H. Goy, et al. "Reliability of Cell-Free DNA (cfDNA) Next Generation Sequencing in Predicting Chromosomal Structural Abnormalities and Cytogenetic-Risk Stratification of Patients with Myeloid Neoplasms." Blood 138, Supplement 1 (2021): 3463. http://dx.doi.org/10.1182/blood-2021-148164.

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Abstract Introduction: Cytogenetic analysis is important for stratifying patients with various myeloid neoplasms. It has been reported that whole-genome sequencing can be used as an alternative to cytogenetic analysis in acute myeloid leukemia (AML) and myelodysplastic syndrome (MDS). With the increasing use of liquid biopsy in the diagnosis and monitoring of patients with various types of neoplasms, we explored the potential of using liquid biopsy and next generation sequencing (NGS) in detecting chromosomal structural abnormalities or copy number variation (CNV) in patients with myeloid neop

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Barboza, Vilmara Pereira, and Marco Antonio Costa. "Cytogenetic Analysis in Trigona spinipes Fabricius (Hymenoptera, Meliponina) Reveals Intraspecific Variation." Neotropical Entomology 50, no. 5 (2021): 846–49. http://dx.doi.org/10.1007/s13744-021-00853-7.

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Cenis, J. L. "Cytogenetic, Enzymatic, and Restriction Fragment Length Polymorphism Variation ofMeloidogynespp. from Spain." Phytopathology 82, no. 5 (1992): 527. http://dx.doi.org/10.1094/phyto-82-527.

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Clay, Alyssa I., Theresa Hahn, Leah Preus, et al. "Evidence for Heterogeneous Genetic Associations with Acute Lymphoblastic Leukemia (ALL) By Cytogenetics and Sex in High-Risk Patients Treated with Matched Unrelated Donor Allogeneic Blood or Marrow Transplant (URD-BMT)." Blood 126, no. 23 (2015): 2621. http://dx.doi.org/10.1182/blood.v126.23.2621.2621.

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Abstract Inherited genetic polymorphisms in ARID5B, GATA3, and IKZF1 have been reported to be associated with ALL and vary by cytogenetic subgroups. For example, ARID5B variants are associated with hyperdiploid B-ALL in pediatric patients, which occurs in approximately 30% of ALL patients and is a marker of good prognosis. In contrast, a variant in GATA3 (rs3824662) has been consistently associated with ALL regardless of cytogenetics. While associations by subtype and across age have been explored in ALL patients, the effect of sex on the association of germline variants with ALL has not been

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Russo, Domenico, Michele Malagola, Chiara Colombi, et al. "Phase II Explorative Study of Intermittent Imatinib (IM) Treatment (INTERIM) in Elderly Patients with Ph+ Chronic Myeloid Leukemia (CML) Who Achieved a Stable Complete Cytogenetic Response (CCgR) with Standard IM Therapy." Blood 112, no. 11 (2008): 4288. http://dx.doi.org/10.1182/blood.v112.11.4288.4288.

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Abstract Standard therapy with Imatinib (i.e. daily administration) significantly prolongs the survival of Ph+ CML patients who obtain a complete cytogenetic response (CCgR). Elderly patients (i.e. &gt; 65 yrs) have similar cytogenetic responses and survival, but they usually show a low compliance. This prospective multicenter trial addresses the issue of intermittent administration of Imatinib (INTERIM) in Ph+ CML patients older than 65 years with stable complete cytogenetic response (CCgR) after at least 2 years of standard therapy with IM. Lower doses of IM could be sufficient to mainta

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Jacobina, Uedson Pereira, Edson Paiva, and Jorge Abdala Dergam. "Pleistocene karyotypic divergence in Hoplias malabaricus (Bloch, 1794) (Teleostei: Erythrinidae) populations in southeastern Brazil." Neotropical Ichthyology 9, no. 2 (2011): 325–33. http://dx.doi.org/10.1590/s1679-62252011005000023.

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The lacustrine system of the middle rio Doce basin is considered a paradigm of Pleistocene geomorphology. In these lakes, two Hoplias malabaricus karyomorphs (2n = 42A and 2n = 42B) live in sintopy in Carioca Lake. Cytogenetic analyses were performed on 65 specimens from 8 lakes (including Carioca Lake) to determine the distribution and relative frequency of these karyomorphs and the degree of cytogenetic divergence caused putatively by recent geographic isolation. All fish were 2n = 42B karyomorphs, except for 1 specimen from the Marola Lake, which was 2n = 42A. Among-population variation was

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Tapia-Pastrana, Fernando, Alfonso Delgado-Salinas, and Javier Caballero. "Patterns of chromosomal variation in Mexican species of Aeschynomene (Fabaceae, Papilionoideae) and their evolutionary and taxonomic implications." Comparative Cytogenetics 14, no. 1 (2020): 157–82. http://dx.doi.org/10.3897/compcytogen.v14i1.47264.

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A cytogenetic analysis of sixteen taxa of the genus Aeschynomene Linnaeus, 1753, which includes species belonging to both subgenera Aeschynomene (Léonard, 1954) and Ochopodium (Vogel, 1838) J. Léonard, 1954, was performed. All studied species had the same chromosome number (2n = 20) but exhibited karyotype diversity originating in different combinations of metacentric, submetacentric and subtelocentric chromosomes, chromosome size and number of SAT chromosomes. The plasticity of the genomes included the observation in a taxon belonging to the subgenus Aeschynomene of an isolated spherical stru

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Tapia-Pastrana, Fernando, Alfonso Delgado-Salinas, and Javier Caballero. "Patterns of chromosomal variation in Mexican species of Aeschynomene (Fabaceae, Papilionoideae) and their evolutionary and taxonomic implications." Comparative Cytogenetics 14, no. (1) (2020): 157–82. https://doi.org/10.3897/CompCytogen.v14i1.47264.

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A cytogenetic analysis of sixteen taxa of the genus Aeschynomene Linnaeus, 1753, which includes species belonging to both subgenera Aeschynomene (Léonard, 1954) and Ochopodium (Vogel, 1838) J. Léonard, 1954, was performed. All studied species had the same chromosome number (2n = 20) but exhibited karyotype diversity originating in different combinations of metacentric, submetacentric and subtelocentric chromosomes, chromosome size and number of SAT chromosomes. The plasticity of the genomes included the observation in a taxon belonging to the subgenus Aeschynomene of an isolated spherical stru

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Roca M., M. Gabriela, Lisete C. Davide, and Maria C. Mendes-Costa. "Cytogenetics of Colletotrichum lindemuthianum (Glomerella cingulata f. sp. phaseoli)." Fitopatologia Brasileira 28, no. 4 (2003): 367–73. http://dx.doi.org/10.1590/s0100-41582003000400004.

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Cytogenetic and morphological studies were conducted with Colletotrichum lindemuthianum (Glomerella cingulata f. sp. phaseoli), the pathogen responsible for anthracnose of common bean (Phaseolus vulgaris). In this species, there is some evidence of genomic variation but it is unknown whether the process occurs in a manner similar to other fungal genetic models. Six isolates from bean plants were used and sexual reproduction was observed in vitro. Meiosis and ascospore formation were investigated by cytogenetical approaches and light microscopy. To study the nucleus and chromosome numbers, a mi

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De Rosa, LVS, F. Foresti, C. Martins, C. Oliveira, PE Sobrinho, and AP Wasko. "Cytogenetic analyses of two Curimatidae species (Pisces; Characiformes) from the Paranapanema and Tietê Rivers." Brazilian Journal of Biology 67, no. 2 (2007): 333–38. http://dx.doi.org/10.1590/s1519-69842007000200020.

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Cytogenetic analyses were performed in two Curimatidae species (Steindachnerina insculpta and Cyphocharax modesta) from the Paranapanema and Tietê Rivers (São Paulo State, Brazil), showing a karyotype composed of 54 meta-submetacentric chromosomes in both species. Silver- and chromomycyn-staining and fluorescent in situ hybridization (FISH) using a 18S rDNA probe indicated that the nucleolar organizer regions (NORs) of both species are localized in the terminal region of the long arm of two metacentric chromosomes. Although a single NOR system was evidenced in both analyzed species, S. insculp

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Jatt, Tahira, Ghulam Sarwar Markhand, Mushtaque Ahmed Jatoi, et al. "Karyotype Evolution and Genetic Variation in Date Palm (Phoenix dactylifera L.) Varieties Cultivated in Pakistan." Planta Animalia 4, no. 2 (2025): 145–54. https://doi.org/10.71454/pa.004.02.0112.

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Due to limited cytogenetic data, the date palm (Phoenix dactylifera L.), a monocotyledonous and dioecious species, previously had uncertain ploidy levels. This study aimed to determine the chromosome number and develop karyotypic profiles for elite commercial date palm cultivars cultivated across four provinces of Pakistan, with additional comparisons to exotic varieties. All analyzed cultivars were confirmed to be diploid, possessing a chromosome number of 2n = 36. Detailed karyotypic analyses were performed, including measurements of total chromosome length (TCL), lengths of short and long a

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Raimondi, Juan Pablo, Ricardo Williams Masuelli, and Elsa Lucila Camadro. "Assessment of somaclonal variation in asparagus by RAPD fingerprinting and cytogenetic analyses." Scientia Horticulturae 90, no. 1-2 (2001): 19–29. http://dx.doi.org/10.1016/s0304-4238(00)00250-8.

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Uwa, Hiroshi, and Lynne R. Parenti. "Morphometric and meristic variation in ricefishes, genusOryzias: a comparison with cytogenetic data." Ichthyological Research 35, no. 2 (1988): 159–66. http://dx.doi.org/10.1007/bf02905401.

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Cornel, Martina C. "Variation in prenatal cytogenetic diagnosis: Policies in 13 european countries, 1989–1991." Prenatal Diagnosis 14, no. 5 (1994): 337–44. http://dx.doi.org/10.1002/pd.1970140504.

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Spies, J. J., H. Du Plessis, N. P. Barker, and S. M. C. Van Wyk. "Cytogenetic studies in the genus Chaetobromus (Poaceae: Arundineae)." Genome 33, no. 5 (1990): 646–58. http://dx.doi.org/10.1139/g90-096.

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The genus Chaetobromus consists of four, somewhat ill defined species. Morphological merging and the existence of intermediates render the separation of these species difficult. A basic chromosome number of x = 6 for Chaetobromus is substantiated by the presence of diploid specimens. The genus forms a polyploid complex, ranging from diploid to duodecaploid. Polyploidy occurs in the form of segmental alloploidy and occasionally as alloploidy. Meiotic abnormalities, in the form of univalents during metaphase I and anaphase laggards, were observed in some specimens. A cancerous growth form, invol

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Lavrenchenko, Leonid, Rena Nadjafova, and Nina Bulatova. "Three new karyotypes extend a Robertsonian fan in Ethiopian spiny mice of the genus Acomys I. Geoffroy, 1838 (Mammalia, Rodentia)." Comparative Cytogenetics 5, no. (5) (2011): 423–31. https://doi.org/10.3897/compcytogen.v5i5.1252.

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Three new karyotypes (2n=40, 44, 52) are described revealing what are probably new cryptic species of Ethiopian spiny mice. Two other diploid numbers have already been reported for the country (2n=36 and 68) and, overall, the five known karyotypic forms constitute a common lineage differentiated by a Robertsonian process. Such arrays of karyotypic forms are known as a ‘Robertsonian fan’. This view of the situation in Ethiopian <i>Acomys</i> I. Geoffroy, 1838 is based on standard chromosomal morphology that reveals a constant FN (68) and needs further investigation of chromosome homology by dif

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Villa Rus, A., J. C. Cigudosa, J. L. Carrasco Juan, et al. "Chromosomal Evolution in Psittaciformes. Revisited." International Journal of Biology 8, no. 4 (2016): 34. http://dx.doi.org/10.5539/ijb.v8n4p34.

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<p class="1Body">With colourful plumage, charismatic character and vocal learning abilities, parrots are one of the most striking and recognizable bird groups. Their attractiveness has drawn human attention for centuries, and members of the Psittaciformes order were, also, among the first avian species to be subject to cytogenetic studies which have contributed to understand their taxonomic and evolutionary relationships.</p><p class="1Body">We present here the karyological results collected by the study of thirteen parrot species new to karyology. These results are additiona

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Andrew, Rose L., Joseph T. Miller, Rod Peakall, Michael D. Crisp, and Randall J. Bayer. "Genetic, cytogenetic and morphological patterns in a mixed mulga population: evidence for apomixis." Australian Systematic Botany 16, no. 1 (2003): 69. http://dx.doi.org/10.1071/sb01043.

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The mulga complex (Acacia aneura and closely related taxa) is a widespread group that is dominant in much of arid Australia. The group is taxonomically difficult, due to a complex interaction of sympatry and putative hybridisation between the major species, geographic variation within species and sympatric variation within A. aneura. Mulga is highly variable in a wide range of vegetative and reproductive characters and it is not unusual to find five or six distinct forms growing side by side. The aim of this project was to gain a better understanding of the relationships among mulga species an

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