Academic literature on the topic 'Cytokines'

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Journal articles on the topic "Cytokines"

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Trinchieri, Giorgio. "Cytokines and cytokine receptors." Immunological Reviews 202, no. 1 (2004): 5–7. http://dx.doi.org/10.1111/j.0105-2896.2004.00217.x.

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Dayer, J. M. "Cytokines and cytokine antagonists." Fresenius' Journal of Analytical Chemistry 343, no. 1 (1992): 33–34. http://dx.doi.org/10.1007/bf00331973.

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Berti, E., and R. Caputo. "Cytokines, cytokine receptors and cytokine antibodies." Melanoma Research 6, SUPPLEMENT 1 (1996): S25. http://dx.doi.org/10.1097/00008390-199609001-00064.

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van Deventer, S. J. H. "Cytokines and cytokine-based therapies." Current Opinion in Gastroenterology 14, no. 4 (1998): 317–21. http://dx.doi.org/10.1097/00001574-199807000-00008.

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Li, Aileen W., and Wendell A. Lim. "Engineering cytokines and cytokine circuits." Science 370, no. 6520 (2020): 1034–35. http://dx.doi.org/10.1126/science.abb5607.

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Burger, D., and J. M. Dayer. "Inhibitory cytokines and cytokine inhibitors." Neurology 45, Issue 6, Supplement 6 (1995): S39—S43. http://dx.doi.org/10.1212/wnl.45.6_suppl_6.s39.

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Ansel, John, Patricia Perry, Jeffrey Brown, et al. "Cytokine Modulation of Keratinocyte Cytokines." Journal of Investigative Dermatology 94, no. 6 (1990): s101—s107. http://dx.doi.org/10.1111/1523-1747.ep12876053.

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Thipphawong, John. "Inhaled cytokines and cytokine antagonists." Advanced Drug Delivery Reviews 58, no. 9-10 (2006): 1089–105. http://dx.doi.org/10.1016/j.addr.2006.07.014.

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Ramani, Thulasi, Carol S. Auletta, Daniel Weinstock, et al. "Cytokines." International Journal of Toxicology 34, no. 4 (2015): 355–65. http://dx.doi.org/10.1177/1091581815584918.

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Over the past 30 years, the world of pharmaceutical toxicology has seen an explosion in the area of cytokines. An overview of the many aspects of cytokine safety evaluation currently in progress and evolving strategies for evaluating these important entities was presented at this symposium. Cytokines play a broad role to help the immune system respond to diseases, and drugs which modulate their effect have led to some amazing therapies. Cytokines may be “good” when stimulating the immune system to fight a foreign pathogen or attack tumors. Other “good” cytokine effects include reduction of an
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Standiford, Theodore. "Anti-inflammatory Cytokines and Cytokine Antagonists." Current Pharmaceutical Design 6, no. 6 (2000): 633–49. http://dx.doi.org/10.2174/1381612003400533.

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Dissertations / Theses on the topic "Cytokines"

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Webb, Ginette Rachel. "Cytokines and cytokine receptors in osteoarthritis." Thesis, University of Bristol, 1997. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.388158.

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Deller, Marc Christian. "Structural studies of cytokines and cytokine receptors." Thesis, University of Cambridge, 1999. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.326028.

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Palmblad, Karin. "Cytokines and cytokine-directed intervention in experimental arthritis /." Stockholm, 2001. http://diss.kib.ki.se/2001/91-628-4589-6/.

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Affò, Silvia. "Cytokines and Cytokine-Receptors in the Pathogenesis of Alcoholic Hepatitis." Doctoral thesis, Universitat de Barcelona, 2014. http://hdl.handle.net/10803/145435.

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By performing a translational study we identified a specific pattern of genes differentially regulated in patients with severe alcoholic hepatitis (AH). A functional analysis of the gene expression profile showed several pathways deregulated in AH, including cytokines- cytokine receptor interaction. Within cytokine-cytokine receptor interaction pathway, Fn14 has been identified as the only receptor belonging to TNF superfamily to be exclusively up-regulated in patients with AH, and its expression has been shown to be associated with severity of the disease and mortality. We observed that Fn14
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Ozaki, Akihiko. "Expression of cytokines and cytokine receptors in human Schwann cells." Kyoto University, 2008. http://hdl.handle.net/2433/135921.

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LU, ZHAO-YANG. "Cytokines et antagonistes de cytokines dans le myelome multiple." Nantes, 1993. http://www.theses.fr/1993NANT2079.

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Notre equipe a montre que l'interleukine-6 (il-6) est un facteur essentiel pour la croissance des cellules plasmocytaires malignes et que des traitements par anticorps anti-il-6 reduisaient croissance tumorale chez 50% des malades. La premiere partie de notre travail a consiste a rechercher les raisons pouvant expliquer une non-reponse au traitement. Nous avons ainsi developpe une methodologie nouvelle permettant de quantifier la production journaliere d'il-6 dans tout l'organisme. Nous avons montre que la production d'il-6 chez les malades non repondeurs etait trop forte, superieure au moins
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Croxford, J. Ludovic. "Gene therapy for experimental allergic encephalomyelitis by delivery of inhibitory cytokines or cytokine inhibitors." Thesis, University College London (University of London), 2000. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.314201.

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Ulfgren, Ann-Kristin. "Cytokines in rheumatoid arthritis /." Stockholm, 2000. http://diss.kib.ki.se/2000/91-628-3823-7/.

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Benrick, Anna. "Cytokines in metabolic functions /." Göteborg : Section of Endocrinology, Institute of Neuroscience and Physiology, The Sahlgrenska Academy at University of Gothenburg, 2008. http://hdl.handle.net/2077/9608.

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Gilmore, William Hans. "Canine pro-inflammatory cytokines." Thesis, University of Liverpool, 1997. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.263791.

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Books on the topic "Cytokines"

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Ibelgaufts, Horst. Dictionary of cytokines. VCH, 1995.

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Meager, Anthony. Cytokines. Prentice Hall, 1991.

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Meager, Anthony. Cytokines. Open University Press, 1990.

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Callard, R. E. The cytokine factsbook. Academic Press, 1994.

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Meager, Anthony. Cytokines. Prentice Hall, 1991.

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A, Wells James, ed. Cytokines. Academic, 1999.

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Meager, A. Cytokines. Open University Press, 1990.

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Constantin, Bona, and Revillard Jean-Pierre, eds. Cytokines and cytokine receptors: Physiology and pathological disorders. Harwood Academic, 2000.

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Westwick, J., I. J. D. Lindley, and S. L. Kunkel, eds. Chemotactic Cytokines. Springer US, 1991. http://dx.doi.org/10.1007/978-1-4684-6009-4.

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1950-, Nicola Nicos, ed. Guidebook to cytokines and their receptors. Oxford University Press, 1994.

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Book chapters on the topic "Cytokines"

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Behrens, Edward M. "Cytokines in Cytokine Storm Syndrome." In Advances in Experimental Medicine and Biology. Springer International Publishing, 2024. http://dx.doi.org/10.1007/978-3-031-59815-9_13.

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Behrens, Edward M. "Cytokines in Cytokine Storm Syndrome." In Cytokine Storm Syndrome. Springer International Publishing, 2019. http://dx.doi.org/10.1007/978-3-030-22094-5_12.

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"CYTOKINES AND CANCER." In Cytokines and Cytokine Receptors. CRC Press, 2001. http://dx.doi.org/10.1201/9781482283716-31.

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"CYTOKINES IN HEMATOPOIESIS." In Cytokines and Cytokine Receptors. CRC Press, 2001. http://dx.doi.org/10.1201/9781482283716-9.

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Cohen, S. B. A., J. Clayton, M. Londei, and M. Feldmann. "T cells and cytokines." In Cytokines. Oxford University PressOxford, 1995. http://dx.doi.org/10.1093/oso/9780199635672.003.0011.

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Abstract The functions of T cells and cytokines are intimately interlinked. It was not until T cell growth factors were defined and subsequently purified, and the cDNA encoding it cloned as ‘interleukin 2’ (1), that abundant non-malignant T cells could be cultured. The isolation of this and other T cell growth factors, now included in the broader category of cytokines, has permitted the development of long-term T cell-lines and clones. T cells can be isolated from normal healthy individuals or patients with disease, according to their antigen specificity and/or phenotype, and then perpetuated
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Schötze, Stefan, and Martin Kronke. "Measurement of cytokine induction of PC-specific phospholipase C and sphingomyelinases." In Cytokines. Oxford University PressOxford, 1995. http://dx.doi.org/10.1093/oso/9780199635672.003.0007.

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Abstract Cytokines play a vital role as mediators of intercellular communication within the immune system. One of the hallmarks of cytokine function is the marked redundancy of biological activities. The overlapping biological functions of TNF/IL-1 and GM-CSF/IL-3 are just two examples. The redundancy of cytokine activities may be based on the utilization of shared key components of intracellular signalling pathways. The principal architecture of major signalling pathways used by cytokines consists of series of proteins including G-proteins, second messenger generating enzymes, protein kinases
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"CYTOKINES AND CYTOKINE MODULATORS." In Meyler's Side Effects of Drugs in Cancer and Immunology. Elsevier, 2010. http://dx.doi.org/10.1016/b978-0-444-53267-1.50006-x.

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O'Shea, John J., Massimo Gadina, and Richard Siegel. "Cytokines and cytokine receptors." In Clinical Immunology. Elsevier, 2013. http://dx.doi.org/10.1016/b978-0-7234-3691-1.00033-7.

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Mak, Tak W., and Mary E. Saunders. "Cytokines and Cytokine Receptors." In The Immune Response. Elsevier, 2006. http://dx.doi.org/10.1016/b978-012088451-3.50019-3.

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O'Shea, John J., Massimo Gadina, Giuseppe Sciumè,, and Françoise Meylan. "Cytokines and Cytokine Receptors." In Clinical Immunology. Elsevier, 2023. http://dx.doi.org/10.1016/b978-0-7020-8165-1.00014-9.

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Conference papers on the topic "Cytokines"

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Kimmel, Jeremy D., Morgan V. DiLeo, Isabella E. Valenti, Gregory A. Gibson, Simon C. Watkins, and William J. Federspiel. "Dynamics of Cytokine Capture Within Hemoadsorption Beads Used to Treat Sepsis." In ASME 2009 Summer Bioengineering Conference. American Society of Mechanical Engineers, 2009. http://dx.doi.org/10.1115/sbc2009-204764.

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Sepsis is a serious medical condition characterized by systemic inflammation caused by infection, and affects more than 750,000 individuals per year in the US, with a mortality rate of approximately 30% [1]. The pathophysiology of sepsis is complex and not entirely understood, but is believed to be related to the dysfunction of multiple interdependent humoral mediator pathways, including redundant release of inflammatory cytokines [2]. Removal of both pro- and anti-inflammatory cytokines from the circulating blood is believed to be a promising therapy for severe sepsis [3]. We are developing a
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Pereira, Clayrton de Barros, Yuri Felix Pedra, and Renata Dellalibera-Joviliano. "Profile of IL-1 beta, INF-gamma, IL-4 and IL-17 in patients with COVID-19." In III SEVEN INTERNATIONAL MULTIDISCIPLINARY CONGRESS. Seven Congress, 2023. http://dx.doi.org/10.56238/seveniiimulti2023-175.

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The immune response to SARS-CoV-2 is mediated by several soluble chemotactic factors, including cytokines whose levels vary at different stages and types of infections. Clinical evidence shows that "cytokine storm," in which the body has high levels of several pro-inflammatory cytokines, is common in several patients with severe COVID-19. Thus, the aim of this study was to evaluate the inflammatory response mediated by the cytokines IL-1 Beta, INF-Gama, IL-4 and IL-17 in patients with COVID. Sandwich-type immunoenzymatic assays (ELISA sandwich) were performed to determine the serum cytokine co
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Jurišić, Vladimir. "POSSIBILITIES OF CYTOKINE DETERMINATION AND THEIR ANALYSIS IN VARIOUS TISSUES." In 1st INTERNATIONAL Conference on Chemo and BioInformatics. Institute for Information Technologies, University of Kragujevac,, 2021. http://dx.doi.org/10.46793/iccbi21.089j.

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Cytokines are small proteins that participate in many interactions between cells of the immune system as well as between many tissue cells including tumors. Currently, there is no universal classification of cytokines and they can be analyzed based on the cells that produce them or based on the type of activity. Cytokines have been studied for many years in medicine firstly in cancer patients in serum, but also in many other diseases including inflammation or other autoimmune diseases or other pathological conditions. Cytokines are still being discovered, and for many of them the structure, bi
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Plotnikova, E. M., I. A. Nesterova, and R. N. Nizamov. "STUDYING THE RESPONSE OF CELL CULTURES TO THE PRESENCE OF CYTOKINES IN THE NUTRITIONAL MEDIUM." In SAKHAROV READINGS 2022: ENVIRONMENTAL PROBLEMS OF THE XXI CENTURY. International Sakharov Environmental Institute of Belarusian State University, 2022. http://dx.doi.org/10.46646/sakh-2022-2-7-10.

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Currently, a new generation of immunomodulators, cytokines, are widely used in medicine and veterinary medicine. Cytokines are active in very low concentrations, they regulate the proliferation and differentiation of cells of the immune system. Taking into account the high biological activity for cells of animal, plant and microbial origin in vivo and in vitro, we conducted the present studies, the purpose of which was to study the possibility of using cytokines as activators of the metabolism of animal cell cultures in vitro for the reproduction of viruses on them. In the experiments, cell cu
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Kruglyakova, M. V., O. V. Smirnova, and N. M. Titova. "CHARACTERISTICS OF THE CYTOKINE PROFILE IN PHYSIOLOGICAL AND COMPLICATED PREGNANCY." In Культура, наука, образование: проблемы и перспективы. Нижневартовский государственный университет, 2021. http://dx.doi.org/10.36906/ksp-2021/79.

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One of the priority tasks of any state is to protect the health of mothers and children. Despite the great advances in diagnostics and methods for preventing the occurrence of pathologies during pregnancy, the percentage of normal births is decreasing every year. One of the most serious complications of pregnancy is preeclampsia, the prevalence of which in the world is increasing every year. This article presents data on the cytokine profile in preeclampsia. The properties and role of the main cytokines in physiological and complicated (preeclampsia) pregnancy, relative to the control group, a
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Wang, Wei, Hamada A. Aboubakr, James Vang, Victor Brenk, Sagar M. Goyal, and James Collins. "Nanomagnetic Biosensor for the Detection of Porcine Interferon Gamma." In 2017 Design of Medical Devices Conference. American Society of Mechanical Engineers, 2017. http://dx.doi.org/10.1115/dmd2017-3375.

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Due to the anatomical and physiological similarities to humans that include similar heart size, flow rate, skin, liver enzymes and bone healing, porcine models as a powerful investigational platform have been widely used in research areas such as diabetes, obesity and islet transplantation [1]. The advantages of relative low cost, ease in handling and comparatively short period of breeding time may make swine provide a promising solution to the shortage of human donors and difficulty in isolating purified islets from adult human in future. Porcine cytokines play a significant role in innate im
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Rippinen, D. V., and A. O. Solovieva. "CHARACTERISATION OF FIBROBLAST-LIKE SYNOVIOCYTES AS THE BASIS OF AN IN VITRO MODEL FOR TESTING DRUGS FOR RHEUMATOID ARTHRITIS THERAPY." In XI МЕЖДУНАРОДНАЯ КОНФЕРЕНЦИЯ МОЛОДЫХ УЧЕНЫХ: БИОИНФОРМАТИКОВ, БИОТЕХНОЛОГОВ, БИОФИЗИКОВ, ВИРУСОЛОГОВ, МОЛЕКУЛЯРНЫХ БИОЛОГОВ И СПЕЦИАЛИСТОВ ФУНДАМЕНТАЛЬНОЙ МЕДИЦИНЫ. IPC NSU, 2024. https://doi.org/10.25205/978-5-4437-1691-6-96.

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Rheumatoid arthritis (RA) is an autoimmune disease, the prevalence and social significance of which is extremely high. To date, there is an active search for effective targeting drugs and relevant in vitro test systems. In this work we have carried out a comparative characterisation of fibroblast-like synoviocyte lines isolated from patients with RA. Their migration rate, cytokine secretion, and response to proinflammatory cytokines were analysed.
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Kuzmina, L. P., A. G. Khotuleva, and M. M. Kolyaskina. "GENETIC POLYMORPHISM OF CYTOKINES FOR OCCUPATIONAL BRONCHO OBSTRUCTIVE DISEASES DEVELOPMENT RISK AND PROGNOSIS ASSESSMENT." In The 17th «OCCUPATION and HEALTH» Russian National Congress with International Participation (OHRNC-2023). FSBSI «IRIOH», 2023. http://dx.doi.org/10.31089/978-5-6042929-1-4-2023-1-265-268.

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One of the significant systems in the pathogenesis of lung diseases is the system of cytokines. Genetic polymorphism of cytokines can be associated with different levels of cytokine production when exposed to a stimulus of the same intensity in response to antigenic irritation, or tissue damage, which can determine individual sensitivity to chemicals. The purpose of this study was to evaluate the presence of associations of single nucleotide polymorphisms of cytokine genes with the development and severity of occupational bronchoobstructive diseases, taking into account the specifics of occupa
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Maidhof, Robert, Neena Rajan, and Nadeen O. Chahine. "Effect of Inflammation on the Osmotic Response of Nucleus Pulposus Cells." In ASME 2012 Summer Bioengineering Conference. American Society of Mechanical Engineers, 2012. http://dx.doi.org/10.1115/sbc2012-80358.

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Intervertebral disc (IVD) degeneration is accompanied by elevated levels of pro-inflammatory cytokines, particularly IL-1β and TNF-α [1]. Disc cells from the nucleus pulposus (NPs) respond to cytokine stimulation with increased catabolic breakdown of the tissue, resulting in a positive feedback of disc integrity loss and further inflammation [2]. Previous studies by our group have examined the response of NP cells to Toll-Like Receptor-4 (TLR-4) activation through stimulation with lipopolysaccharide (LPS). TLR-4 is a pattern recognition receptor that is activated in innate immunity and by poly
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Ригер, Николай Александрович, Элеонора Николаевна Трушина, and Андрей Николаевич Тимонин. "INFLUENCE OF HIGH PHYSICAL LOADS ON THE IMMUNOREGULATORY STATUS OF ATHLETES." In Сборник избранных статей по материалам научных конференций ГНИИ "Нацразвитие" (Санкт-Петербург, Август 2022). Crossref, 2022. http://dx.doi.org/10.37539/aug304.2022.84.56.002.

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В статье приводятся данные изучения цитокинового профиля (определение уровней содержания интерлейкинов: IL-4, IL-10, IL-18 и γ-интерферона (γ-IFN) методом твердофазного иммуноферментного анализа у17 спортсменов - биатлонистов высшей спортивной квалификации и 17 здоровых добровольцев со средней физической активностью. Полученные результаты подтверждают значительную вариабельность содержания иммунорегуляторных цитокинов в сыворотке крови здоровых людей. Повышение уровней провоспалительных цитокинов у спортсменов свидетельствует о напряженности иммунного ответа при интенсивных физических нагрузка
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Reports on the topic "Cytokines"

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Xu, Guochao, and Xiaozhou Mao. The level of TH1 cytokines, TH2 cytokines and TH17 cytokines in patients with COVID-19 infection : A meta-analysis. INPLASY - International Platform of Registered Systematic Review and Meta-analysis Protocols, 2023. http://dx.doi.org/10.37766/inplasy2023.8.0023.

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Mao, xiaozhou, sheng Zheng, and jiangyan Luo. Imbalance of TH 1 cytokines, TH 2 cytokines and associated cytokines in patients with chronic hepatitis B : A meta-analysis. INPLASY - International Platform of Registered Systematic Review and Meta-analysis Protocols, 2023. http://dx.doi.org/10.37766/inplasy2023.2.0034.

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Kurtzman, Scott H. Cytokines, Neovascularization and Breast Cancer. Defense Technical Information Center, 1998. http://dx.doi.org/10.21236/ada371368.

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Kurtzman, Scott H. Cytokines, Neovascularization and Breast Cancer. Defense Technical Information Center, 1998. http://dx.doi.org/10.21236/ada383239.

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Zeng, Yulin, Liwei Wang, Hai Zhou, and Yu Qi. Th1/Th2 cytokine profiles differentiating tuberculous from malignant pleural effusions: A systematic review and meta-analysis. INPLASY - International Platform of Registered Systematic Review and Meta-analysis Protocols, 2022. http://dx.doi.org/10.37766/inplasy2022.1.0005.

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Review question / Objective: To clarify which one has a different predominance of Th1 and Th2 immune responses in malignant and tuberculous pleural effusions. We did a meta-analysis of the results published previously to assess the levels of Th1/Th2 cytokines in two types of pleural effusion and evaluated its ability to distinguish TPE from MPE. Condition being studied: Malignant and tuberculous pleural effusions are the two most common types of exudative pleural effusions, both of which can be seen with the typical accumulation of lymphocytes. Immune responses mediated by either the Th1 or Th
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lv, Haibing, meng Guo, Chuang Guo, and Kuanjun He. The Interrelationships Between Cytokines and Schizophrenia:A Systematic review. INPLASY - International Platform of Registered Systematic Review and Meta-analysis Protocols, 2024. http://dx.doi.org/10.37766/inplasy2024.7.0128.

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Tumwasorn, Somying, and Asada Leelahavanichkul. Effect of Lactobacillus and Bifidobacterium on the inhibition of Clostridium difficile in mouse infection model. Chulalongkorn University, 2018. https://doi.org/10.58837/chula.res.2018.25.

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Clostridium difficile is a major cause antibiotic-associated diarrhea and colitis in patients with broad-spectrum antibiotic therapy. A disruption of the gut microbiota by using antibiotics results in colonization with C. difficile and release of toxins that cause leaky gut and the production inflammatory cytokines. We identified six specific strains of Lactobacillus or Bifidobacterium are able to reduce leaky gut and inflammation caused by C. difficile in vitro. In this study, we aim to investigate the effect of these strains either alone or in combination on the inhibition of C. difficile in
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Grimley, Phillip M. Use of Cytokines to Prevent Breast Cancer Growth and Progression. Defense Technical Information Center, 1996. http://dx.doi.org/10.21236/ada325362.

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Bhowmick, Neil A. Regulation and Function of Cytokines that Predict Prostate Cancer Metastasis. Defense Technical Information Center, 2012. http://dx.doi.org/10.21236/ada569356.

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Grimley, Philip M. Use of Cytokines to Prevent Breast Cancer Growth and Progression. Defense Technical Information Center, 1997. http://dx.doi.org/10.21236/ada339111.

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