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Journal articles on the topic 'Cytologie – urine'

Author: Grafiati

Published: 29 March 2025

Last updated: 31 July 2025

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1

Lau, Paul, Joseph L. Chin, Stephen Pautler, Hassan Razvi, and Jonathan I. Izawa. "NMP22 is predictive of recurrence in high-risk superficial bladder cancer patients." Canadian Urological Association Journal 3, no. 6 (2013): 454. http://dx.doi.org/10.5489/cuaj.1173.

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Introduction: The nuclear matrix protein 22 (NMP22) assay hasbeen shown to have greater sensitivity for the diagnosis and detectionof recurrent urothelial carcinoma of the bladder (UCB) overthat of traditional urine cytology. We assessed the use of NMP22to predict which high-risk superficial UCB patients will have recurrence,progression or disease-related death; we compared theseresults to standard urine cytology.Methods: One hundred consecutive patients with high-risk superficialUCB were enrolled. During surveillance, urine was collectedfor cytology and NMP22 testing. Patients were followed f

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Pitra, Tomáš, Marie Dikanová, Milan Hora, Michal Michal, Ondřej Hes, and Kristýna Pivovarčíková. "Correlation of invasive methods and urine cytology in detection of urothelial neoplasms: one centre early experience with application of The Paris System for Reporting Urinary Cytology." Czech Urology 22, no. 4 (2018): 275–84. https://doi.org/10.48095/cccu2018042.

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Tatomirovic, Zeljka, Radojka Bokun, Ljljana Ignjatovic, Anastasija Aleksic, Vesna Skuletic, and Jovan Dimitrijevic. "The significance of cytologic examination of urine in the diagnosis of renal allograft dysfunction." Vojnosanitetski pregled 60, no. 3 (2003): 299–304. http://dx.doi.org/10.2298/vsp0303299t.

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Background. This paper presents our experience with cytologic examination of urine in diagnosing renal allograft dysfunction. Methods. The study group included 23 patients with renal allograft dysfunction, selected from 56 patients who underwent renal transplantation. Etiologic diagnosis was made according to the clinical picture, histological findings during allograft biopsy, and cytologic examination of urine. Urine sediment was obtained in cytocentrifuge and was air dried and stained with May Grunwald Giemsa. Results. Out of 23 patients with allograft dysfunction in 18 (78.3%) patient it wa

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Astvatsaturyan, Kristine, David Frishberg, and Arsen Ramazyan. "Cytology of the Urinary Tract: Specimen Sampling, Preparation, Adequacy, and Normal Cellular Components." CMAS Journal 1 (April 17, 2024): 2. http://dx.doi.org/10.25259/cmasj_04_01.

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Urine evaluation is one of the oldest tests used in ancient medicine. Cytologic examination of urine is a simple, non-invasive, cost effective, and reliable method to uncover a wide variety of reactive and neoplastic processes in urothelium. Urinary tract lesions are often multifocal, may be inapparent on cystoscopic examination or inaccessible to directly biopsy. Thus, urine cytology remains one of the most common methods for the initial diagnosis of urothelial carcinoma that may be manageable with early detection. In this article we review indications for urine cytology, sampling techniques,

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Longo, Thomas Andrew, Ajay Gopalakrishna, Joseph J. Fantony, and Brant Allen Inman. "Your opinion counts: How do you treat atypical/suspicious cytology?" Journal of Clinical Oncology 34, no. 2_suppl (2016): 463. http://dx.doi.org/10.1200/jco.2016.34.2_suppl.463.

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463 Background: Urine cytology has often been reported as a highly specific but poorly sensitive test. Cytology is reported as positive, negative, atypical, or suspicious. Atypical/suspicious cytologies account for roughly a quarter of the results and present a clinical dilemma. Physicians’ risk aversion means they are typically treated as positive and result in clinical action. We test the effects of this assumption on sensitivity and specificity. Methods: After IRB approval, we queried clinical and pathology databases to identify all subjects at Duke University Medical Center who had undergo

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Barkan, Güliz A., Eva M. Wojcik, Ritu Nayar, et al. "The Paris System for Reporting Urinary Cytology: The Quest to Develop a Standardized Terminology." Acta Cytologica 60, no. 3 (2016): 185–97. http://dx.doi.org/10.1159/000446270.

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The main purpose of urine cytology is to detect high-grade urothelial carcinoma (HGUC). With this principle in mind, The Paris System (TPS) Working Group, composed of cytopathologists, surgical pathologists, and urologists, has proposed and published a standardized reporting system that includes specific diagnostic categories and cytomorphologic criteria for the reliable diagnosis of HGUC. This paper outlines the essential elements of TPS and the process that led to the formation and rationale of the reporting system. The Paris System Working Group, organized at the 2013 International Congress

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Sharma, Anurag, Shivani Sharma, Niharika Patnaik, et al. "Cytomorphologic and Immunophenotypic Profile of a Cohort of Small Cell Carcinoma of the Urinary Bladder." Acta Cytologica 60, no. 5 (2016): 475–80. http://dx.doi.org/10.1159/000449399.

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Background: The incidence of primary small cell carcinoma (SCC) of the urinary bladder is extremely rare. We sought to analyze the cytologic and immunophenotypic features of SCC of the urinary bladder in urine and reassert the importance of cytologic examination of urine specimens for diagnosis of this tumor. Methods: We studied the clinical and cytomorphologic features in the presurgical urine specimens (4 voided urine and 2 bladder-washing specimens) of histopathologically and immunohistochemically proven cases of SCC of the urinary bladder. Results: There were 6 cases, all males, with an ag

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Boccafoschi, C., F. Montefiore, S. Treffiletti, D. Signorello, and A. Langé. "Preliminary comparative considerations about urinary cytology and the Bard BTA test in the diagnosis and follow-up of superficial bladder cancer." Urologia Journal 62, no. 1_suppl (1995): 88–90. http://dx.doi.org/10.1177/039156039506201s23.

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— The value of urinary cytology in the diagnosis and follow-up of superficial transitional cell carcinoma of the bladder is well known. Results of traditional cytologic examinations may be affected by the different methods of urine collection, preservation, manipulation and observation of the samples so that more objective tools are desirable. The aim of this study in to compare the traditional cytologic examinations with a new diagnostic in-vitro test (Bard BTA test), which can detect antigen complexes in the urine due to the contact of the tumour cells with the basement membrane. The Bard BT

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Umar, Ahmed M., Uzodimma E. Onwuasoanya, Emmanuel U. Oyibo, Adamu Dahiru, and Ismaila A. Mungadi. "The pattern of urine cytology among patients with clinical diagnosis of bladder tumor in a tertiary hospital northwest Nigeria." International Surgery Journal 6, no. 10 (2019): 3521. http://dx.doi.org/10.18203/2349-2902.isj20194402.

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Background: Urine cytology is a simple, safe, non-invasive and cheap investigation that is used as adjunct to cystoscopy in the diagnosis of bladder cancer. Its low sensitivity is a major limitation against its use as a sole diagnostic test for bladder cancer. The objective of this study was to determine the pattern of urine cytology seen in patients with clinical diagnosis of bladder tumour in our practice.Methods: This is a retrospective study of patients with clinical diagnosis of bladder tumour that had urine cytology in our centre. The age and gender of the patients, number of urine cytol

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Mendoza, R. P., T. Haidary, and R. Gupta. "Paris System Has A Higher Cytohistologic Correlation And Reproducibility Than Traditional Urine Cytology Method." American Journal of Clinical Pathology 154, Supplement_1 (2020): S94. http://dx.doi.org/10.1093/ajcp/aqaa161.206.

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Abstract Introduction/Objective The major limitation of urine cytology is the lack of consensus regarding the terminology and diagnostic criteria that should be used for urothelial atypia. The main goal of the newly proposed Paris System for Reporting Urine Cytology is to concentrate primarily on the detection of high grade urothelial carcinoma while minimizing the detection of low grade lesions. This study aimed to apply the criteria and categories of the Paris system in retrospectively collected urine cytology specimens and assess histologic correlation and reproducibility. Methods Two senio

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Badruddoza, SM, FA Azim, AJE Nahar Rahman, et al. "Cytohistologic Correlation of Urothelial Cancers– A study of 57 Cases." TAJ: Journal of Teachers Association 30, no. 1 (2018): 1–10. http://dx.doi.org/10.3329/taj.v30i1.39114.

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Transitional cell carcinoma (TCC) comprises about 90% of all primary tumors of urinary bladder. The accuracy of multiple voided urine cytology justifies its continued use as a first line diagnostic and detection technique, particularly for high grade invasive cancers and clinically unsuspected case of carcinoma particularly carcinoma in-situ. In this study 57 cases were taken to see correlation of cytology, histology, stage, morphological pattern and sensitivity and specificity of urothelial cancers. Out of 57, 53 (92.99)% were positive for malignancy and 4(7.01%) were negative. There were 14

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Oh, Han Yeong, Ha Ju So, Seong Hyun Kim, Dong Wook Kim, and Hyun Chang Kim. "The Development of the Liquid Cell Smear Device for Liquid-Based Cytology Test." Applied Mechanics and Materials 284-287 (January 2013): 1564–68. http://dx.doi.org/10.4028/www.scientific.net/amm.284-287.1564.

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This paper describes the development and validation of the liquid cell smears device for early cancer detection. In this study, the liquid cell smears device with the automated production of cell slides for Liquid-based Cytology Test has been developed. To validate the Liquid cell smear device, we used each 100 samples related to cervix, sputum, urine, body fluids, and thyroid. Experimental conditions were divided into five, which were the distance of the cylinder, the moving party's ascent and descent distance, and time to stop the smears. After staining, their verification was conducted thro

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Tatomirovic, Zeljka, Radojka Bokun, Jovan Dimitrijevic, Ljiljana Ignjatovic, Anastasija Aleksic, and Rajko Hrvacevic. "The value of urine cytologic examination findings in the diagnosis of the acute renal allograft rejection." Vojnosanitetski pregled 60, no. 1 (2003): 35–41. http://dx.doi.org/10.2298/vsp0301035t.

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Background. Acute rejection of allograft is one of the most serious complications of renal transplantation that requires fast and precise diagnostic approach. In this paper our experience in cytologic urinalysis as a diagnostic method of the acute renal allograft rejection was reviewed. Methods. The study group included 20 of 56 patients with transplanted kidneys who were assumed for the acute allograft rejection according to allograft dysfunction and/or urine cytology findings. Histological findings confirmed allograft rejection in 4 patients. Urine sediment obtained in cytocentrifuge was air

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Pillay, Pavitra, Lisette van Lieshout, Myra Taylor, et al. "Cervical cytology as a diagnostic tool for female genital schistosomiasis: Correlation to cervical atypia and Schistosoma polymerase chain reaction." CytoJournal 13 (April 20, 2016): 10. http://dx.doi.org/10.4103/1742-6413.180784.

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Background: Female genital schistosomiasis (FGS) is a tissue reaction to lodged ova of Schistosoma haematobium in the genital mucosa. Lesions can make the mucosa friable and prone to bleeding and discharge. Women with FGS may have an increased risk of HIV acquisition, and FGS may act as a cofactor in the development of cervical cancer. Objectives: To explore cytology as a method for diagnosing FGS and to discuss the diagnostic challenges in low-resource rural areas. The correlation between FGS and squamous cell atypia (SCA) is also explored and discussed. Cytology results are compared to Schis

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Moretti, M., B. Malcangi, A. Cichero, P. Pittaluga, M. Varaldo, and A. Decensi. "Follow-Up Del Carcinoma Vescicale Superficiale: Approccio Integrato e Ipotesi Prognostiche." Urologia Journal 61, no. 1_suppl (1994): 7–10. http://dx.doi.org/10.1177/039156039406101s01.

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The follow-up of superficial bladder cancer, after TUR and endovesical administration of BCG or other drugs, involves many methods: we studied two groups of patients who underwent TUR for superficial bladder cancer. A group of 54 patients underwent cystoscopy, urine cytologic examination and cytometry; a second group of 30 patients underwent mapping too. The results of the three examinations were compared: high ploidy values were related both with recurrence and progression. The results of cytology plus cytometry were predictive of mapping results and bladder biopsies were useless in up to 50%

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Sofocleous, C. T., K. T. Brown, S. Savage, et al. "Upper urinary tract metastases from adenocarcinoma of the colon." Acta Radiologica 46, no. 4 (2005): 437–40. http://dx.doi.org/10.1080/02841850510021229.

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An unusual presentation of colorectal metastasis to the upper urinary tract is reported. The metastasis manifested as a filling defect seen during antegrade pyelography. Cytologic evaluation of aspirated material demonstrated metastatic colonic adenocarcinoma. A dilated collecting system may be caused by intraluminal material including tumor and blood clots. Whenever fixed filling defects are encountered, urine cytology should be sent even in the absence of renal parenchymal involvement by tumor. The cytological evaluation may allow for prompt diagnosis and treatment.

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Tomašov, Martina. "New trends in urine cytology." Urologie pro praxi 22, no. 1 (2021): 19–21. http://dx.doi.org/10.36290/uro.2021.003.

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Yamazaki, Hiroyuki, Tsuneyuki Wada, Hiroshi Asano, Hiromasa Fujita, Kazuhira Okamoto, and Hidemichi Watari. "Comparison between Urine and Cervical High-Risk HPV Tests for Japanese Women with ASC-US." Diagnostics 11, no. 10 (2021): 1895. http://dx.doi.org/10.3390/diagnostics11101895.

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Most uterine cervical cancers are caused by the persistent infection of the high-risk human papillomavirus (hrHPV). Thus, the hrHPV-DNA test, which examines specimens from the cervix, is the standard screening method as well as cytology in western countries. Urine sampling for the hrHPV-DNA test would be easier and help improving screening rates. This study prospectively investigated the concordance between urine and cervical hrHPV tests for patients with atypical squamous cells of undetermined significance (ASC-US) in cervical cytology. We recruited 338 women with the cytologic diagnosis of A

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Yamazaki, Hiroyuki, Tsuneyuki Wada, Hiroshi Asano, Hiromasa Fujita, Kazuhira Okamoto, and Hidemichi Watari. "Comparison between Urine and Cervical High-Risk HPV Tests for Japanese Women with ASC-US." Diagnostics 11, no. 10 (2021): 1895. http://dx.doi.org/10.3390/diagnostics11101895.

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Most uterine cervical cancers are caused by the persistent infection of the high-risk human papillomavirus (hrHPV). Thus, the hrHPV-DNA test, which examines specimens from the cervix, is the standard screening method as well as cytology in western countries. Urine sampling for the hrHPV-DNA test would be easier and help improving screening rates. This study prospectively investigated the concordance between urine and cervical hrHPV tests for patients with atypical squamous cells of undetermined significance (ASC-US) in cervical cytology. We recruited 338 women with the cytologic diagnosis of A

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Peña, Karla B., Francesc Riu, Anna Hernandez, Carmen Guilarte, Joan Badia, and David Parada. "Usefulness of the Urine Methylation Test (Bladder EpiCheck®) in Follow-Up Patients with Non-Muscle Invasive Bladder Cancer and Cytological Diagnosis of Atypical Urothelial Cells—An Institutional Study." Journal of Clinical Medicine 11, no. 13 (2022): 3855. http://dx.doi.org/10.3390/jcm11133855.

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Urothelial bladder cancer is a heterogeneous disease and one of the most common cancers worldwide. Bladder cancer ranges from low-grade tumors that recur and require long-term invasive surveillance to high-grade tumors with high mortality. After the initial contemporary treatment in non-muscle invasive bladder cancer, recurrence and progression rates remain high. Follow-up of these patients involves the use of cystoscopies, cytology, and imaging of the upper urinary tract in selected patients. However, in this context, both cystoscopy and cytology have limitations. In the follow-up of bladder

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Dr., D. G. Jaiswal, and S. D. Dakhure Dr. "Utility of Urine Cytology in Urinary Tract Neoplasm with Histopathological Correlation." International Journal of Science and Healthcare Research 4, no. 3 (2019): 199–204. https://doi.org/10.5281/zenodo.3935451.

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<strong>Background:</strong> Urinary bladder tumor is the sixth most common tumor diagnosed worldwide. Urine cytology is an important screening tool of patients for urothelial carcinoma (UC) and follow-up of patients with treated disease. The aim of this study to determine the sensitivity of urine cytology in detection of urinary tract neoplasms with its clinical and histopathological correlation. <strong>Material & Methods:</strong> A five years prospective study includes 73 cases of urine cytology from January 2014 to December 2018 at a tertiary care hospital in the Depart

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Arville, Brent, Emily O’Rourke, Fai Chung, Mahul Amin, and Shikha Bose. "Evaluation of a triple combination of cytokeratin 20, p53 and CD44 for improving detection of urothelial carcinoma in urine cytology specimens." CytoJournal 10 (December 27, 2013): 25. http://dx.doi.org/10.4103/1742-6413.123784.

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Background: Atypical urine cytology results trigger cystoscopy or molecular tests, both of which are costly, complex and difficult to perform tests. Several immunostains are being investigated to improve cancer detection; however, cytology material is limited and restricts the use of multiple immunostains. This study was designed to determine the utility of a cocktail of three stains, cytokeratin (CK20), p53 and CD44 in urine cytology samples for improving the detection of urothelial carcinoma. Materials and Methods: Urine cytology specimens with cell blocks containing adequate cytologic mater

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Brown, Felix M. "URINE CYTOLOGY." Urologic Clinics of North America 27, no. 1 (2000): 25–37. http://dx.doi.org/10.1016/s0094-0143(05)70231-7.

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Vap, Linda M., and Sarah B. Shropshire. "Urine Cytology." Veterinary Clinics of North America: Small Animal Practice 47, no. 1 (2017): 135–49. http://dx.doi.org/10.1016/j.cvsm.2016.07.009.

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Glass, Ryan, Lisa Rosen, Karen Chau, et al. "Analysis of the Cytomorphological Features in Atypical Urine Specimens following Application of The Paris System for Reporting Urinary Cytology." Acta Cytologica 62, no. 1 (2017): 54–61. http://dx.doi.org/10.1159/000481278.

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Background: This study investigates the use of The Paris System (TPS) for Reporting Urinary Cytopathology and examines the performance of individual and combined morphological features in atypical urine cytologies. Methods: We reviewed 118 atypical cytologies with subsequent bladder biopsies for the presence of several morphological features and reclassified them into Paris System categories. The sensitivity and specificity of individual and combined features were calculated along with the risk of malignancy. Results: An elevated nuclear-to-cytoplasmic ratio was only predictive of malignancy i

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Jones, Eleanor R., Suzanne Carter, Helena O'Flynn, et al. "DEveloping Tests for Endometrial Cancer deTection (DETECT): protocol for a diagnostic accuracy study of urine and vaginal samples for the detection of endometrial cancer by cytology in women with postmenopausal bleeding." BMJ Open 11, no. 7 (2021): e050755. http://dx.doi.org/10.1136/bmjopen-2021-050755.

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IntroductionPostmenopausal bleeding (PMB), the red flag symptom for endometrial cancer, triggers urgent investigation by transvaginal ultrasound scan, hysteroscopy and/or endometrial biopsy. These investigations are costly, invasive and often painful or distressing for women. In a pilot study, we found that voided urine and non-invasive vaginal samples from women with endometrial cancer contain malignant cells that can be identified by cytology. The aim of the DEveloping Tests for Endometrial Cancer deTection (DETECT) Study is to determine the diagnostic test accuracy of urine and vaginal cyto

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Smith, A., M. E. Nielsen, J. Ferguson, et al. "Patterns of utilization of urine-based markers in non-muscle-invasive bladder cancer: Results from the BCAN/SUO/AUA/LUGPA electronic survey." Journal of Clinical Oncology 29, no. 7_suppl (2011): 261. http://dx.doi.org/10.1200/jco.2011.29.7_suppl.261.

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261 Background: In addition to cytologic evaluation, there are currently four urine-based tests approved by the FDA for bladder cancer detection. At this point, the Guidelines panels from the AUA and EAU do not make specific recommendations about the ideal role of these tests. Furthermore, there is a paucity of data on current patterns of care in this area of practice. Methods: An electronic survey was developed by the Bladder Cancer Advocacy Network (BCAN) to elicit self-reported practices of the use of cytology and urine-based markers in the settings of general use, surveillance, and assessm

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Raab, Stephen S., Dana Marie Grzybicki, Colleen M. Vrbin, and Kim R. Geisinger. "Urine Cytology Discrepancies." American Journal of Clinical Pathology 127, no. 6 (2007): 946–53. http://dx.doi.org/10.1309/xuvxfxmfpl7telce.

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Choi, Song-Yi, Kyung-Hee Kim, Kwang-Sun Suh, and Min-Kyung Yeo. "Diagnostic significance of dual immunocytochemical staining of p53/cytokeratin20 on liquid-based urine cytology to detect urothelial carcinoma." Cytojournal 17 (February 27, 2020): 3. http://dx.doi.org/10.25259/cytojournal_88_2019.

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Background: Urine cytology is a noninvasive and inexpensive method; however, it is limited in low sensitivity for detecting and monitoring urothelial carcinoma (UC). To overcome limitation of cytology, several tests using urine samples have been attempted that immunocytochemical staining is an inexpensive and easy to perform ancillary technique. Dual immunocytochemical staining for p53 and cytokeratin 20 (CK20) is assessed in liquid-based urine cytology slides. Materials and Methods: Liquid-based urine cytology samples collected between 2008 and 2013 and matched follow-up biopsy samples of hig

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Schnadig, Vicki J., Adekunle Adesokan, Durwood Neal, and Zoran Gatalica. "Urinary Cytologic Findings in Patients With Benign and Malignant Adenomatous Polyps of the Prostatic Urethra." Archives of Pathology & Laboratory Medicine 124, no. 7 (2000): 1047–52. http://dx.doi.org/10.5858/2000-124-1047-ucfipw.

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Abstract Context.—Urethral adenomatous polyps with prostatic epithelium (also known as benign prostatic epithelial polyps [BPEPs]) are a documented cause of hematuria, dysuria, and hematospermia, conditions that may prompt cytologic evaluation of urine. Design.—The urine cytologic test findings in 5 cases of biopsy-proven BPEPs and in 1 case of prostatic ductal adenocarcinoma (PDA) that presented as a urethral polyp were retrospectively evaluated. Immunocytochemical stain for prostate-specific antigen (PSA), prostatic acid phosphatase (PAP), and high-molecular-weight cytokeratin (34βE12) were

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Khattab, Ruba, Hui Zhu, and Jordan Reynolds. "Cytologic-histologic Correlation of Benign/Metaplastic Bladder Conditions with Urine Cytology: A Retrospective Slide Review." Journal of the American Society of Cytopathology 3, no. 5 (2014): S30. http://dx.doi.org/10.1016/j.jasc.2014.09.062.

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Lee, Paul, Christopher Owens, and Andrew Fischer. "Sensitivity of Urine Cytology for High Grade Urothelial Carcinoma and Explanations for False-Negative Cytologies." Journal of the American Society of Cytopathology 4, no. 6 (2015): S19—S20. http://dx.doi.org/10.1016/j.jasc.2015.09.043.

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Viswanath, S., B. Zelhof, E. Ho, K. Sethia, and R. Mills. "Is Routine Urine Cytology Useful in the Haematuria Clinic?" Annals of The Royal College of Surgeons of England 90, no. 2 (2008): 153–55. http://dx.doi.org/10.1308/003588408x242006.

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INTRODUCTION The objective of this study was to determine the value of routine urine cytology in the initial evaluation of patients presenting to a one-stop haematuria clinic. PATIENTS AND METHODS A total of 1000 consecutive patients who attended the haematuria clinic between June 2003 and November 2004 were studied prospectively. A standard protocol was used to investigate these patients. This included urine cytology, upper tract imaging and flexible cystoscopy. RESULTS Overall, 986 samples of urine were sent for cytology. In 126 patients, the report was abnormal; of these, 71 patients were f

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Kaur, Dr Kanwalpreet. "Role of CK20 immunocytochemistry as an adjuvant to urine cytology in the detection of urothelial malignancy." Journal of Medical Science and clinical Research 12, no. 11 (2024): 48–54. https://doi.org/10.18535/jmscr/v12i11.07.

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Introduction: Urine cytology has been a non-invasive method of choice for detecting urothelial carcinomas but it has several drawbacks including low sensitivity for low grade urothelial lesions, morphology being easily affected by infection, instrumentation, surgery, chemo or immune therapy. Additional screening tests with high sensitivity and specificity for urothelial tumours of all grades are indicated to help improve the diagnostic ability of urine cytology as well as to reduce the need for frequent cystoscopies, especially in those with low-risk disease. Objective: We studied the role of

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Ikeda, H., Y. Ishida, T. Dejima, M. Nomura, and H. Sanefuji. "The significance of urine NMP22 in the screening of urothelial cancer (comparison of ELISA and immunochromatography method)." Journal of Clinical Oncology 27, no. 15_suppl (2009): e16024-e16024. http://dx.doi.org/10.1200/jco.2009.27.15_suppl.e16024.

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e16024 Background: The early diagnosis of urothelial cancer allows for effective local treatment and optimizes the success of surgical therapy. Urine nuclear matrix protein 22 (NMP22) was introduced for the detection of transitional cell carcinoma. Add to old NMP22 (ELISA), new NMP22 (immunochromotography method : BladderChek) can be available from 2004. The objective of this study is to determine whether there are any correlation between urine NMP22 (two methods) and the grade or stage of urothelial cancer, and whether it can serve as a biochemical marker of urothelial cancer. Methods: A tota

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Ann Pereira, Loretta, Hilda Fernandes, and Amritha Chidambaram. "Implementing the Paris System into Reclassifying Urine Cytology: A Descriptive Analysis." International Journal of Science and Research (IJSR) 10, no. 11 (2021): 399–403. https://doi.org/10.21275/art20193124.

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Jateen, Anshuman, Pritish Patnaik Pritam, Panda Sabyasachi, et al. "A Comparison of Urinary Cytology and Histopathological Study in Urinary Bladder Transitional Cell Carcinoma at Our Institute in a Prospective Study." International Journal of Pharmaceutical and Clinical Research 16, no. 1 (2024): 1304–13. https://doi.org/10.5281/zenodo.11116413.

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<strong>Background: </strong>Urine cytology is a standard diagnostic test to aid in diagnosis of bladder cancer. It detects the exfoliated cells from urinary tract and helps identify the presence of malignancy. The prognostic value of conventional cytology to monitor patients with superficial bladder carcinoma is well established. The study aims to correlate urine cytology with histopathology of the bladder transitional cell carcinoma and to study the role of urinary cytology in its diagnosis. <strong>Methods: </strong>70 Patients admitted in Department of Urology, SCB Medical C

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Saharti, Samah, Hessa Aljhdali, Rana Ajabnoor, et al. "Cytospin performance when using Paris system for reporting urinary cytology." Cytojournal 19 (August 5, 2022): 47. http://dx.doi.org/10.25259/cytojournal_48_2021.

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Objectives: The Paris System (TPS) for Reporting Urine Cytology has significantly improved the approach to evaluating urine cytology. TPS criteria were defined mainly according to ThinPrep and SurePath preparations, as they are widely utilized. The objective of this study is to validate urine cytology interpretation according to the TPS classification using cytospin technique in relation to the gold slandered histology. Material and Methods: This retrospective study examined and analyzed 316 urine specimens from King Abdulaziz University Hospital between 2015 and 2020. Cytospin technique is pe

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Curling, Marigold, G. Broome, and W. F. Hendry. "How Accurate is Urine Cytology?" Journal of the Royal Society of Medicine 79, no. 6 (1986): 336–38. http://dx.doi.org/10.1177/014107688607900609.

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Exfoliative urinary cytology was performed on 260 new cases of histologically proven urothelial cancer. The site, size, shape and histological grade of the tumours were documented, and they were classified by the TNM system. Overall, urine cytology was positive in 135 (52%), suspicious in 28 (11%) and negative in 97 (38%) cases. Malignant cells were found most often when the urothelial tumours were large, papillary and solid, moderately or poorly differentiated and invasive (T2–4). Most upper tract tumours and those situated in bladder diverticula had positive urinary cytology. This study conf

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Zaharopoulos, Paul, Jick Y. Wong, and Julie W. Wen. "Matrix crystals in cytologic urine specimens." Diagnostic Cytopathology 6, no. 6 (1990): 390–95. http://dx.doi.org/10.1002/dc.2840060604.

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Ranade, Ranjana Shashidhar, Netra Prakash Kori, and Vidisha Sharatchandra Athanikar. "Utility of Urine Cytology in Genitourinary Lesions and Implication of Paris System in the Diagnosis of Urothelial Carcinoma - Five Years of Experience from a Tertiary Care Centre at North Karnataka." Journal of Evidence Based Medicine and Healthcare 8, no. 02 (2021): 58–63. http://dx.doi.org/10.18410/jebmh/2021/12.

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BACKGROUND Urine cytology when combined with cystoscopy remains a gold standard in screening and surveillance of urothelial carcinoma. Paris system for reporting urine cytology (PSRUC) gives seven well defined diagnostic criteria. We aimed to analyse utility of urine cytology in patients with urogenital symptoms, compare existing institutional system (EIS) with PSRUC and assess the performance of both reporting systems in predicting subsequent high-grade urothelial carcinoma on histopathology. METHODS A five year retrospective study included a total of 146 urine samples from 74 patients. Each

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Jess, Heidi, Alaa Afify, and Eric Huang. "A Retrospective Review of Atypical Clusters in Urine Cytology: Analysis of Cytologic Features and Clinical Significance." Journal of the American Society of Cytopathology 1, no. 1 (2012): S28. http://dx.doi.org/10.1016/j.jasc.2012.08.059.

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Shadab, Rangrez, Saziya R. Bidi, Shridhar C. Ghagane, and R. B. Nerli. "EMERGING ROLE OF URINARY BIOMARKERS IN DETECTION OF UROTHELIAL BLADDER CARCINOMA IN SOUTH INDIAN POPULATION." Journal of Advanced Scientific Research 13, no. 09 (2022): 104–12. http://dx.doi.org/10.55218/jasr.202213914.

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Urine cytology is used for screening of exfoliated bladder cells from voided urine but lacks sensitivity. This study aims to check the efficacy of 5-aminolevulinic acid (5- ALA) fluorescence cytology and establish a high sensitivity approach in detecting flat, in-situ and/or small lesions that are hardly visible under conventional cystoscopy. Intracellular PPIX allows red fluorescence detection. In this study, 5-ALA fluorescent cytology using urine was compared with conventional cytology in the diagnosis of bladder tumors. In this prospective study, we compared the sensitivity and specificity

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Rahman, Mohammad Shafiqur, ASM Azizur Rahman Siddique, Mohammad Saiful Islam, and Faika Farah Ahmed. "Combined urine Cytology and Cystoscopy can detect recurrence of superficial transitional cell carcinoma of the urinary bladder." Bangabandhu Sheikh Mujib Medical University Journal 12, no. 1 (2019): 1–5. http://dx.doi.org/10.3329/bsmmuj.v12i1.38821.

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The study was aimed to evaluate the accuracy of combined urine cytology and cystoscopy for the detection of recurrence of superficial transitional cell carcinoma of the urinary bladder without bladder biopsy. Total 60 patients of superficial TCC of urinary bladder were selected of these 48 were male and 12 were female with age were between 41 to 80 years (mean age- 63.15 years).Urine cytology was done for all patients .Then cystoscopy done with targeted biopsy taken from any apparently visible growth in the bladder and systematic biopsy were taken where there was no growth. Reports of the cyto

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Abdulwahab-Ahmed, Abdullahi, Kabiru Abdullahi, Mohammed A. Umar, Ngwobia P. Agwu, Abubakar S. Muhammad, and Abdullahi Khalid. "The pattern of urine cytology in a tertiary health care facility Northwest Nigeria." International Surgery Journal 6, no. 5 (2019): 1458. http://dx.doi.org/10.18203/2349-2902.isj20191866.

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Background: Urine cytology is an important investigation in the management of urothelial cancer. It is particularly an important test in the management of urinary tract cancers because of its non-invasive nature. Objective of study to review our practice of urine cytology as a diagnostic tool in the management of urinary tract pathology.Methods: A seventeen years retrospective study from 1st January, 2001 to 31st December, 2017 where records of patients who had urine cytology in Usmanu Danfodio University Teaching Hospital (UDUTH), Sokoto, Nigeria were reviewed and data was extracted and analy

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Allison, Derek B., Rajni Sharma, Morgan L. Cowan, and Christopher J. VandenBussche. "Evaluation of Sienna Cancer Diagnostics hTERT Antibody on 500 Consecutive Urinary Tract Specimens." Acta Cytologica 62, no. 4 (2018): 302–10. http://dx.doi.org/10.1159/000489181.

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Objectives: Telomerase activity can be detected in up to 90% of urothelial carcinomas (UC). Telomerase activity can also be detected in urinary tract cytology (UTC) specimens and indicate an increased risk of UC. We evaluated the performance of a commercially available antibody that putatively binds the telomerase reverse transcriptase (hTERT) subunit on 500 UTC specimens. Study Design: Unstained CytospinTM preparations were created from residual urine specimens and were stained using the anti-hTERT antibody (SCD-A7). Two algorithms were developed for concatenating the hTERT result and cytolog

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Auwal, S., SU Alhassan, AA Sani, et al. "Efficacy of Urine Cytology in the Diagnosis of Bladder Cancer in Aminu Kano Teaching Hospital: Comparism of Cytology and Histological Findings." Nig J Uro 10, no. 1 & 2 (2020): 17–23. https://doi.org/10.5281/zenodo.6569755.

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<strong>ABSTRACT</strong> <strong>Background: </strong>Bladder cancer is a common urologic malignancy worldwide and second most common genitourinary malignancy after prostate cancer. Diagnosis of bladder cancer in developing countries is challenging. Despite the varying results in detection rate of bladder cancer by using the urine cytology, the method can be used in developing countries such as Nigeria, where there are limited diagnostic facilities. <strong>Objective: </strong>The general objective of the study was to determine the efficacy of urine cytology in the diagnosis of bladder cancer

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Kral, Milan, Pavel Zemla, David Hradil, et al. "Iodinated Contrast Medium Affects Urine Cytology Assessment: A Prospective, Single-Blind Study and Its Impact on Urological Practice." Diagnostics 12, no. 10 (2022): 2483. http://dx.doi.org/10.3390/diagnostics12102483.

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During endoscopic procedures for suspected urothelial tumors of the upper urinary tract, radiographic imaging using an iodinated contrast medium is often required. However, following ureteropyelography, we detected changes in cytology characteristics not correlating with real cytology findings in naive urine. The aim of our study was to assess cytology changes between naive and postcontrast urine according to The Paris System of cytology classification. Methods: We prospectively assessed urine samples from 89 patients (23 patients with histologically proven urothelial cancer and 66 healthy vol

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Shukla, Prakriti, and Tushar Ojha. "Risk Prediction of Bladder Carcinomas in Atypical Urine Specimens by Redefining Diagnostic Cytomorphological Criteria." Acta Medica International 12, no. 1 (2025): 1–6. https://doi.org/10.4103/amit.amit_92_24.

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Abstract Introduction: Urine cytology in bladder tumors is challenging due to the lack of definite cytomorphological criteria in categorizing atypical cases. The study aims to re-evaluate atypia in the light of three definitive cytological parameters (high N/C ratio, hyperchromasia, and irregular nuclear contours) and correlate with the follow-up histopathology and cytopathology with an attempt to redefine the morphological features that would aid in distinguishing reactive atypia from malignancy. Materials and Methods: A retrospective analysis of 56 atypical urine specimens was performed cons

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Guo, Aiye, Xiuhua Wang, Juan Shi, Changyi Sun, and Zhen Wan. "Bladder tumour antigen (BTA stat) test compared to the urine cytology in the diagnosis of bladder cancer: A meta-analysis." Canadian Urological Association Journal 8, no. 5-6 (2014): 347. http://dx.doi.org/10.5489/cuaj.1668.

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Introduction: We evaluate the diagnostic value of bladder tumour antigen (BTA stat) tests compared with urine cytology test in detecting bladder cancer.Methods: We searched public databases including PubMed, MEDLINE Springer, Elsevier Science Direct, Cochrane Library and Google Scholar before December 2012. To collect relevant data of BTA stat tests and urine cytology tests in patients with bladder cancer, we studied meta-analyses of sensitivity, specificity, positive likelihood ratio (LR), negative LR and diagnostic odds ratios (DOR) of BTA stat tests and cytology tests from published studies

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