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Journal articles on the topic 'Cytopathic effect'

Author: Grafiati

Published: 4 June 2021

Last updated: 26 July 2025

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1

Rogers, Susan, and Dale W. Vance. "Unusual cytopathic effect in tissue culture." Clinical Microbiology Newsletter 7, no. 1 (1985): 7. http://dx.doi.org/10.1016/s0196-4399(85)80016-7.

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2

Saravanan, Chandrassegar, Zhiyi Cao, Janardan Kumar, et al. "Milk Components InhibitAcanthamoeba-Induced Cytopathic Effect." Investigative Opthalmology & Visual Science 49, no. 3 (2008): 1010. http://dx.doi.org/10.1167/iovs.07-1130.

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3

Vojtkovská, Veronika, Dana Lobová, Eva Voslářová, and Vladimír Večerek. "Impact of the Application of Gaseous Ozone on Selected Pathogens Found in Animal Shelters and Other Facilities." Animals 13, no. 20 (2023): 3230. http://dx.doi.org/10.3390/ani13203230.

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Correctly selecting disinfection procedures is crucial in facilities housing a high number of animals as it directly affects their health. The aim of this study was to verify the virucidal effect of gaseous ozone delivered by commercially available generators under controlled experimental conditions on a selection of viral pathogens (feline coronavirus, canine coronavirus, feline calicivirus, feline parvovirus) commonly found in shelters and other facilities. Two ozone generators with outputs of 3.5 g/h and 20 g/h were used to produce ozone. Virus viability after the application of ozone was e

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4

Cao, Zhiyi. "Effect of Human Tears on Acanthamoeba-Induced Cytopathic Effect." Archives of Ophthalmology 126, no. 3 (2008): 348. http://dx.doi.org/10.1001/archophthalmol.2007.74.

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5

Kavi, J., I. Chant, M. Maris, and P. E. Rose. "CYTOPATHIC EFFECT OF VEROTOXIN ON ENDOTHELIAL CELLS." Lancet 330, no. 8566 (1987): 1035. http://dx.doi.org/10.1016/s0140-6736(87)92609-2.

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6

Deshmukh, Dr Chanchal. "Study The Cytopathic Effect of BmNPV in The BOMBYX MORI Ovarian Cell Lines." Paripex - Indian Journal Of Research 3, no. 5 (2012): 243–44. http://dx.doi.org/10.15373/22501991/may2014/76.

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7

Muddu Krishna, C., J. N. Kolla, Hari Babu Bollikolla, T. Sravan Kumar Reddy, and S. Asha. "Ethyl Gallate: Promising Cytoprotective against HIV-1-Induced Cytopathy and Antiretroviral-Induced Cytotoxicity." Advances in Virology 2023 (July 12, 2023): 1–8. http://dx.doi.org/10.1155/2023/6727762.

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Introduction. HIV-1 infection in cell culture is typically characterized by certain cytopathic effects such as vacuolization of cells and development of syncytia, which further lead to cell death. In addition, the majority of drugs during HIV treatment exhibit serious adverse effects in patients, apart from their beneficial role. During the screening of cytoprotective agents to protect the cells from HIV-1-associated cell death and also drug-associated toxicity, antioxidants from a natural source are assumed to be a choice. A well-known antioxidant, ethyl gallate (EG), was selected for cytopro

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8

El-tanani, Shaimaa, Thangal Yumnamcha, Lalit Pukhrambam Singh, and Ahmed S. Ibrahim. "Differential Effects of Cytopathic Hypoxia on Human Retinal Endothelial Cellular Behavior: Implication for Ischemic Retinopathies." International Journal of Molecular Sciences 23, no. 8 (2022): 4274. http://dx.doi.org/10.3390/ijms23084274.

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Loss of barrier integrity of retinal endothelial cells (RECs) is an early feature of ischemic retinopathies (IRs), but the triggering mechanisms remain incompletely understood. Previous studies have reported mitochondrial dysfunction in several forms of IRs, which creates a cytopathic hypoxic environment where cells cannot use oxygen for energy production. Nonetheless, the contribution of cytopathic hypoxia to the REC barrier failure has not been fully explored. In this study, we dissect in-depth the role of cytopathic hypoxia in impairing the barrier function of REC. We employed the electric

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9

Bezek, David M., Yrjö T. Gröhn, and Edward J. Dubovi. "Effect of acute infection with noncytopathic or cytopathic bovine viral diarrhea virus isolates on bovine platelets." American Journal of Veterinary Research 55, no. 8 (1994): 1115–19. http://dx.doi.org/10.2460/ajvr.1994.55.08.1115.

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Summary A total of 21 calves were inoculated IV with 1 of the following isolates of bovine viral diarrhea virus (BVDV); CD87 (n = 10), NY-1 (n = 3), NADL (n = 5), or were sham-inoculated with virus-free medium (n = 3). Subsequent to inoculation, platelet counts were monitored to detect differences between noncytopathic (CD87, NY-1) and cytopathic (NADL) isolates in their ability to induce thrombocytopenia. Platelet count decrease throughout infection was statistically analyzed by comparing the slope of the line drawn from the count on the day of infection to the lowest count achieved by that c

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10

Kuropka, Piotr, Maciej Dobrzynski, Barbara Bazanow, et al. "A Study of the Impact of Graphene Oxide on Viral Infection Related to A549 and TC28a2 Human Cell Lines." Materials 14, no. 24 (2021): 7788. http://dx.doi.org/10.3390/ma14247788.

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Graphene has been one of the most tested materials since its discovery in 2004. It is known for its special properties, such as electrical conductivity, elasticity and flexibility, antimicrobial effect, and high biocompatibility with many mammal cells. In medicine, the antibacterial, antiviral, and antitumor properties of graphene have been tested as intensively as its drug carrying ability. In this study, the protective effect of graphene oxide against Rubella virus infection of human lung epithelial carcinoma cells and human chondrocyte cells was examined. Cells were incubated with graphene

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11

Wales, Samantha Q., Diana Ngo, Kaoru Hida, and Michael Kulka. "Temperature and density dependent induction of a cytopathic effect following infection with non-cytopathic HAV strains." Virology 430, no. 1 (2012): 30–42. http://dx.doi.org/10.1016/j.virol.2012.04.010.

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12

Taylor, W. M., M. S. Pidherney, H. Alizadeh, and J. Y. Niederkorn. "In vitro Characterization of Acanthamoeba castellanii Cytopathic Effect." Journal of Parasitology 81, no. 4 (1995): 603. http://dx.doi.org/10.2307/3283860.

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13

Sam, Afshin, Felicia Goodrum, Robert Ricciotti, Kenneth Knox, and Richard Sobonya. "Medical image of the week: CMV cytopathic effect." Southwest Journal of Pulmonary and Critical Care 9, no. 6 (2014): 341–42. http://dx.doi.org/10.13175/swjpcc161-14.

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14

HOLLYER, TARAS T., PAT A. DEGAGNE, and MICHELLE J. ALFA. "Characterization of the Cytopathic Effect of Haemophilus ducreyi." Sexually Transmitted Diseases 21, no. 5 (1994): 247–57. http://dx.doi.org/10.1097/00007435-199409000-00002.

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15

Croissant, Odile, Françoise Breitburd, and Gérard Orth. "Specificity of cytopathic effect of cutaneous human papillomaviruses." Clinics in Dermatology 3, no. 4 (1985): 43–55. http://dx.doi.org/10.1016/0738-081x(85)90048-3.

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16

GONZÁLEZ-ROBLES, ARTURO, AMPARO LÁZARO-HALLER, MARTHA ESPINOSA-CANTELLANO, FERNANDO ANAYA-VELÁZQUEZ, and ADOLFO MARTÍNEZ-PALOMO. "Trichomonas vaginalis: Ultrastructural Bases of the Cytopathic Effect." Journal of Eukaryotic Microbiology 42, no. 5 (1995): 641–51. http://dx.doi.org/10.1111/j.1550-7408.1995.tb05921.x.

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17

Espinosa-Cantellano, Martha, Arturo González-Robles, Bibiana Chávez, et al. "Entamoeba dispar: infrastructure, Surface Properties and Cytopathic Effect." Journal of Eukaryotic Microbiology 45, no. 3 (1998): 265–72. http://dx.doi.org/10.1111/j.1550-7408.1998.tb04535.x.

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18

IWATA, Akira, Noriko MIZUKOSHI IWATA, Toshiki SAITO, Kazushige HAMADA, Yoshihiro SOKAWA, and Susumu UEDA. "Cytopathic Effect Inhibition Assay for Canine Interferon Activity." Journal of Veterinary Medical Science 58, no. 1 (1996): 23–27. http://dx.doi.org/10.1292/jvms.58.23.

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19

Chavez, B., L. Gonzalezmariscal, R. Cedillorivera, and A. Martinezpalomo. "Giardia lamblia:In Vitro Cytopathic Effect of Human Isolates." Experimental Parasitology 80, no. 1 (1995): 133–38. http://dx.doi.org/10.1006/expr.1995.1015.

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20

LeBlanc, Robert E., and Zahra Maleki. "Herpes simplex viral cytopathic effect in urine cytology." Diagnostic Cytopathology 41, no. 1 (2011): 61–62. http://dx.doi.org/10.1002/dc.21809.

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21

Papageorgiou, Konstantinos, Aikaterini Stoikou, Dimitrios K. Papadopoulos, et al. "Pseudorabies Virus Prevalence in Lung Samples of Hunted Wild Boars in Northwestern Greece." Pathogens 13, no. 11 (2024): 929. http://dx.doi.org/10.3390/pathogens13110929.

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Aujeszky’s Disease, caused by the pseudorabies virus (PRV), is an acute, often fatal disease affecting mainly pigs and incidentally other animals. While eradicated in several countries, PRV persists in wild boar populations, posing a risk to domestic pigs. This study investigates PRV prevalence in wild boars in the region of Epirus, located in the northwest of Greece. During the 2021–2022 hunting season, 110 lung samples from hunted wild boars were collected and analyzed for PRV DNA and cytopathic effects in cell cultures. PRV DNA was detected in 19 samples (17.3%), 18 of which exhibiting cyto

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22

Kharseeva, Galina Georgievna, A. A. Alieva, L. P. Alekseeva, Ye O. Mangutov, and L. A. Shovkun. "CYPOPATHIC EFFECT OF DIPHTHERIA PATHOGEN IN THE COMPOSITION OF BIOFILM." Russian Clinical Laboratory Diagnostics 64, no. 11 (2019): 681–85. http://dx.doi.org/10.18821/0869-2084-2019-64-11-681-685.

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When the nasopharynx is colonized with toxigenic strains of the diphtheria pathogen, toxin is released, which contributes to the death of epithelial cells. But in bacterial carriers, the development of the clinical picture of the disease does not occur. This is due to the peculiarities of the state of their immune system, as well as the peculiarities of the production of diphtheria exotoxin by corynebacteria in the biofilm. Goal. Determining the nature of the cytopathic effect of C. diphtheriae as part of a biofilm in CHO-K1 cell culture. The planktonic and biofilm (120- and 720-hour) cultures

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23

Hallam, Jennifer C., Sofia Sandalli, Iris Floria, et al. "D-Serine reduces the expression of the cytopathic genotoxin colibactin." Microbial Cell 10, no. 3 (2023): 63–77. http://dx.doi.org/10.15698/mic2023.03.793.

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Some Escherichia coli strains harbour the pks island, a 54 kb genomic island en-coding the biosynthesis genes for a genotoxic compound named colibactin. In eukaryotic cells, colibactin can induce DNA damage, cell cycle arrest and chro-mosomal instability. Production of colibactin has been implicated in the devel-opment of colorectal cancer (CRC). In this study, we demonstrate the inhibito-ry effect of D-Serine on the expression of the pks island in both prototypic and clinically-associated colibactin-producing strains and determine the implications for cytopathic effects on host cells. We also

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24

George, Kathleen M., Lucia P. Barker, Diane M. Welty, and P. L. C. Small. "Partial Purification and Characterization of Biological Effects of a Lipid Toxin Produced byMycobacterium ulcerans." Infection and Immunity 66, no. 2 (1998): 587–93. http://dx.doi.org/10.1128/iai.66.2.587-593.1998.

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ABSTRACT Organisms in the genus Mycobacterium cause a variety of human diseases. One member of the genus, M. ulcerans, causes a necrotizing skin disease called Buruli ulcer. Buruli ulcer is unique among mycobacterial diseases in that the organisms at the site of infection are extracellular and there is little acute inflammatory response. Previous literature reported the presence of a toxin in the culture supernatant of M. ulcerans which causes a cytopathic effect on the mouse fibroblast cell line L929 in which the adherent cells round up and detach from the tissue culture plate. Here we report

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25

Kilapandal Venkatraman, Sindhuja Murali, Paolo Gattuso, and Lin Cheng. "Vanishing Viral Cytopathic Effect Diagnoses in the Cytopatholoogy Laboratory." Journal of the American Society of Cytopathology 10, no. 5 (2021): S45. http://dx.doi.org/10.1016/j.jasc.2021.07.073.

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26

Gadea, I., J. Zapardiel, P. Ruiz, M. I. Gegúndez, J. Esteban, and F. Soriano. "Cytopathic effect mimicking virus culture due to Mycobacterium tuberculosis." Journal of Clinical Microbiology 31, no. 9 (1993): 2517–18. http://dx.doi.org/10.1128/jcm.31.9.2517-2518.1993.

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27

Cromeans, T., H. A. Fields, and M. D. Sobsey. "Replication Kinetics and Cytopathic Effect of Hepatitis A Virus." Journal of General Virology 70, no. 8 (1989): 2051–62. http://dx.doi.org/10.1099/0022-1317-70-8-2051.

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28

Consales, Cleide A., Ronaldo Z. Mendonca, Neusa M. F. Gallina, and Carlos A. Pereira. "Cytopathic effect induced by rabies virus in McCoy cells." Journal of Virological Methods 27, no. 3 (1990): 277–85. http://dx.doi.org/10.1016/0166-0934(90)90096-x.

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29

González-Robles, Arturo, Lizbeth Salazar-Villatoro, Maritza Omaña-Molina, Jacob Lorenzo-Morales, and Adolfo Martínez-Palomo. "Acanthamoeba royreba: Morphological features and in vitro cytopathic effect." Experimental Parasitology 133, no. 4 (2013): 369–75. http://dx.doi.org/10.1016/j.exppara.2013.01.011.

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30

Laurent-Crawford, Anne G., Bernard Krust, Sylviane Muller, et al. "The cytopathic effect of hiv is associated with apoptosis." Virology 185, no. 2 (1991): 829–39. http://dx.doi.org/10.1016/0042-6822(91)90554-o.

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31

Fenyö, Eva Maria, Jan Albert, and Birgitta Åsjö. "Replicative capacity, cytopathic effect and cell tropism of HIV." Aids 3, Supplement (1989): S5–12. http://dx.doi.org/10.1097/00002030-198901001-00002.

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32

Bruss, Volker. "Revisiting the cytopathic effect of hepatitis B virus infection." Hepatology 36, no. 6 (2002): 1327–29. http://dx.doi.org/10.1002/hep.1840360605.

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33

Xu, Zixi, Wange Lou, Wenxin Lu, and Wenxia Wei. "Cell State Recognition of Cytopathic Effect with YOLO Detector." Journal of Physics: Conference Series 2456, no. 1 (2023): 012029. http://dx.doi.org/10.1088/1742-6596/2456/1/012029.

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Abstract Cell state recognition and evaluation of its life cycle are the fundamental and critical procedure to identify the pathological mechanism of viruses and analyze pharmacodynamic effectiveness. Modern life science research is based on large-scale biological experiments so that it is inefficiency to estimate and decide the physicochemical results on petri dishes. With the development of target recognition in computer science, especially YOLO (You Only Look Once) approach, we are able to incorporate unified, real-time object detection into cell state recognition in this paper, which reali

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34

Zhang, Hangchun, Shih-Pong Chao, Li-Hua Ping, Ken Grace, Berwyn Clarke, and Stanley M. Lemon. "An Infectious cDNA Clone of a Cytopathic Hepatitis A Virus: Genomic Regions Associated with Rapid Replication and Cytopathic Effect." Virology 212, no. 2 (1995): 686–97. http://dx.doi.org/10.1006/viro.1995.1526.

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35

Carthy, Christopher M., David J. Granville, Kathleen A. Watson, et al. "Caspase Activation and Specific Cleavage of Substrates after Coxsackievirus B3-Induced Cytopathic Effect in HeLa Cells." Journal of Virology 72, no. 9 (1998): 7669–75. http://dx.doi.org/10.1128/jvi.72.9.7669-7675.1998.

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ABSTRACT Coxsackievirus B3 (CVB3), an enterovirus in the familyPicornaviridae, induces cytopathic changes in cell culture systems and directly injures multiple susceptible organs and tissues in vivo, including the myocardium, early after infection. Biochemical analysis of the cell death pathway in CVB3-infected HeLa cells demonstrated that the 32-kDa proform of caspase 3 is cleaved subsequent to the degenerative morphological changes seen in infected HeLa cells. Caspase activation assays confirm that the cleaved caspase 3 is proteolytically active. The caspase 3 substrates poly(ADP-ribose) pol

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36

Kim, Eunhee, Joo Hang Kim, Taeyoung Koo, Joo Hyuk Sohn, and Chae Ok Yun. "Increased Cytopathic Effect of Replicating Adenovirus Expressing Adenovirus Death Protein." Cancer Research and Treatment 35, no. 5 (2003): 425–32. http://dx.doi.org/10.4143/crt.2003.35.5.425.

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37

Alfa, M. J. "Cytopathic effect of Haemophilus ducreyi for human foreskin cell culture." Journal of Medical Microbiology 37, no. 1 (1992): 43–50. http://dx.doi.org/10.1099/00222615-37-1-43.

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38

Chao, Alexander T., Boon Heng Lee, Kah Fei Wan, et al. "Development of a Cytopathic Effect-Based Phenotypic Screening Assay againstCryptosporidium." ACS Infectious Diseases 4, no. 4 (2018): 635–45. http://dx.doi.org/10.1021/acsinfecdis.7b00247.

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39

Ayala, Gustavo, Thomas M. Wheeler, Moshe Shalev, et al. "Cytopathic effect of in situ gene therapy in prostate cancer." Human Pathology 31, no. 7 (2000): 866–70. http://dx.doi.org/10.1053/hupa.2000.8453.

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40

Vasconcelos, D., M. Oglesbee, and E. Norrby. "The cellular stress response increases measles virus-induced cytopathic effect." Journal of General Virology 79, no. 7 (1998): 1769–73. http://dx.doi.org/10.1099/0022-1317-79-7-1769.

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41

DOYSABAS, Karla Cristine C., Mami OBA, Tomoki ISHIBASHI, et al. "ATeam technology for detecting early signs of viral cytopathic effect." Journal of Veterinary Medical Science 82, no. 3 (2020): 387–93. http://dx.doi.org/10.1292/jvms.20-0021.

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42

Poncet, Delphine, Anne-Laure Pauleau, Gyorgy Szabadkai, et al. "Cytopathic effects of the cytomegalovirus-encoded apoptosis inhibitory protein vMIA." Journal of Cell Biology 174, no. 7 (2006): 985–96. http://dx.doi.org/10.1083/jcb.200604069.

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Replication of human cytomegalovirus (CMV) requires the expression of the viral mitochondria–localized inhibitor of apoptosis (vMIA). vMIA inhibits apoptosis by recruiting Bax to mitochondria, resulting in its neutralization. We show that vMIA decreases cell size, reduces actin polymerization, and induces cell rounding. As compared with vMIA-expressing CMV, vMIA-deficient CMV, which replicates in fibroblasts expressing the adenoviral apoptosis suppressor E1B19K, induces less cytopathic effects. These vMIA effects can be separated from its cell death–inhibitory function because vMIA modulates c

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43

Hashimoto, Naoyuki, Hiroshi Tazawa, Satoru Kikuchi, et al. "Abstract 7241: Combination of CDK4/6 inhibitor promotes the antitumor effect of oncolytic adenovirus against canine breast cancer cells." Cancer Research 84, no. 6_Supplement (2024): 7241. http://dx.doi.org/10.1158/1538-7445.am2024-7241.

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Abstract Background: Oncolytic virotherapy has emerged as a novel antitumor platform to induce tumor-specific cytopathic effect against human cancer cells. However, whether oncolytic virotherapy is effective to canine cancer cells remains unclear. We developed telomerase-specific oncolytic adenoviruses OBP-301 and a p53-armed OBP-702 based on human adenovirus serotype 5. OBP-301 and OBP-702 have therapeutic potential against various types of human cancer cells. As recent report has suggested that human adenovirus serotype 5 induces cytopathic effect against canine cancer cells, OBP-301 and OBP

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44

Payment, Pierre, and Michel Trudel. "Influence of inoculum size, incubation temperature, and cell culture density on virus detection in environmental samples." Canadian Journal of Microbiology 31, no. 11 (1985): 977–80. http://dx.doi.org/10.1139/m85-185.

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The influence of inoculum size and cell culture density on virus titer by cytopathic effect or plaque assay was studied using poliovirus type 1 and BGM (Buffalo green monkey) cells as a model for this evaluation. With a plaque assay system, a linear relationship was observed for an inoculum size of up 1 mL/25 cm2; a marked decrease in the number of plaques was observed when over 1 mL of sample was inoculated on this surface area. Cell culture density also affected virus titer; maximal titers were observed when cells were seeded at 25 000 to 75 000 cells/mL and incubated for 6 days before infec

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45

Huelsenbeck, Johannes, Stefanie Dreger, Ralf Gerhard, Holger Barth, Ingo Just, and Harald Genth. "Difference in the Cytotoxic Effects of Toxin B from Clostridium difficile Strain VPI 10463 and Toxin B from Variant Clostridium difficile Strain 1470." Infection and Immunity 75, no. 2 (2006): 801–9. http://dx.doi.org/10.1128/iai.01705-06.

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ABSTRACT Glucosylation of RhoA, Rac1, and Cdc42 by Clostridium difficile toxin B from strain VPI 10463 (TcdB) results in actin reorganization (cytopathic effect) and apoptosis (cytotoxic effect). Toxin B from variant C. difficile strain 1470 serotype F (TcdBF) differs from TcdB with regard to substrate proteins, as it glucosylates Rac1 and R-Ras but not RhoA and Cdc42. In this study, we addressed the question of whether the cellular effects of the toxins depend on their protein substrate specificity. Rat basophilic leukemia (RBL) cells were synchronized using the thymidine double-block techniq

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46

Yun, Chae-Ok, Eunhee Kim, Taeyoung Koo, Hoguen Kim, Young-sook Lee, and Joo-Hang Kim. "ADP-overexpressing adenovirus elicits enhanced cytopathic effect by induction of apoptosis." Cancer Gene Therapy 12, no. 1 (2004): 61–71. http://dx.doi.org/10.1038/sj.cgt.7700769.

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47

McCaughey, Conall, Xiaohong Shi, Richard M. Elliott, Dorothy E. Wyatt, Hugh J. O’Neill, and Peter V. Coyle. "Low pH-induced cytopathic effect—a survey of seven hantavirus strains." Journal of Virological Methods 81, no. 1-2 (1999): 193–97. http://dx.doi.org/10.1016/s0166-0934(99)00042-7.

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48

Moe, K. T., M. Singh, P. Gopalakrishnakone, et al. "Cytopathic effect of Blastocystis hominis after intramuscular inoculation into laboratory mice." Parasitology Research 84, no. 6 (1998): 450–54. http://dx.doi.org/10.1007/s004360050428.

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49

Hofmann, J., M. W. Pletz, and U. G. Liebert. "Rubella virus-induced cytopathic effect in vitro is caused by apoptosis." Journal of General Virology 80, no. 7 (1999): 1657–64. http://dx.doi.org/10.1099/0022-1317-80-7-1657.

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50

Duval, R., S. Delebassée, P. J. P. Cardot, and C. Bosgiraud. "Visna virus-induced cytopathic effect in vitro is caused by apoptosis." Archives of Virology 147, no. 5 (2002): 943–59. http://dx.doi.org/10.1007/s00705-001-0791-1.

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