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Dissertations / Theses on the topic 'Cytoplasmic and Nuclear Transcription'

Author: Grafiati

Published: 4 June 2021

Last updated: 4 February 2022

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1

Vu, Anthony. "Nuclear and Cytoplasmic Roles of the Transcription factor REST." Diss., [La Jolla] : University of California, San Diego, 2009. http://wwwlib.umi.com/cr/ucsd/fullcit?p1469263.

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Thesis (M.S.)--University of California, San Diego, 2009.<br>Title from first page of PDF file (viewed Oct. 7, 2009). Available via ProQuest Digital Dissertations. Includes bibliographical references (p. 58-61).

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2

Li, Yong. "Cytoplasmic domain of CD44 acts as a nuclear transcription regulator." Karlsruhe : FZKA, 2004. http://bibliothek.fzk.de/zb/berichte/FZKA6917.pdf.

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3

Holter, Elin. "Modulation of nuclear receptor activity by a unique class of corepressors /." Stockholm, 2004. http://diss.kib.ki.se/2004/91-7140-039-7/.

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4

Osman, Waffa. "Modulation of nuclear receptor function by interacting proteins /." Stockholm : Karolinska institutet, 2007. http://diss.kib.ki.se/2007/978-91-7357-264-4/.

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5

Ruan, Xuan 1974. "Differential circadian regulation of Bmal1 transcription by orphan nuclear receptors." Thesis, McGill University, 2008. http://digitool.Library.McGill.CA:80/R/?func=dbin-jump-full&object_id=112358.

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In mammals, circadian rhythms are generated by transcriptional-translational feedback loops consisting of a set of clock genes and their protein products. Among them, Bmal1 is a critical clock gene in generating and maintaining circadian rhythms. Moreover, orphan nuclear receptors REV-ERBs and RORs were known to respectively repress and activate Bmal1 transcription. In our study, we further demonstrated that: (1) REV-ERBalpha might be the main regulator in maintaining Bmal1 oscillation in thymus. (2) Rorgamma mRNA is constant in muscle and testis, and rhythmic in liver, while Rorgammat mRNA is

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6

Li, Yong [Verfasser]. "Cytoplasmic domain of CD44 acts as a nuclear transcription regulator / Forschungszentrum Karlsruhe GmbH, Karlsruhe. Yong Li." Karlsruhe : FZKA, 2004. http://d-nb.info/971463921/34.

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7

Loinder, Kristina. "Nuclear receptor corepressor N-CoR : role in transcriptional repression /." Linköping : Univ, 2004. http://www.bibl.liu.se/liupubl/disp/disp2004/med869s.pdf.

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8

Wallén, Åsa. "Some aspects of nuclear receptor function in the CNS : novel roles of Nurr1 and RXR in developing and mature neurons /." Stockholm, 2002.

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9

Lindquist, Per J. G. "Molecular cloning and characterization of the murine acyl-CoA thioesterase CTE-I /." Stockholm, 2004. http://diss.kib.ki.se/2004/91-7349-878-5/.

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10

Skogsberg, Josefin. "PPAR delta : its role in cholesterol metabolism /." Stockholm, 2003. http://diss.kib.ki.se/2003/91-7349-604-9.

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11

Båvner, Ann. "Molecular mechanisms of transcriptional repression by the orphan receptor SHP /." Stockholm, 2005. http://diss.kib.ki.se/2005/91-7140-212-8/.

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12

Kannisto, Katja. "The metabolic syndrome : studies on thrifty genes /." Stockholm, 2004. http://diss.kib.ki.se/2004/91-7140-051-6/.

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13

Wu, Xiaoyang. "Regulation of Nuclear Hormone Receptors by Corepressors and Coactivators: a Dissertation." eScholarship@UMMS, 2001. https://escholarship.umassmed.edu/gsbs_diss/106.

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Nuclear hormone receptors (NHR) constitute a superfamily of ligand inducible transcriptional activators that enable an organism to regulate development and homeostasis through switching on or off target genes in response to stimuli reflecting changes in environment as well as endocrine. NHRs include classical steroid hormone receptors (GR, AR, ER and MR) and retinoid, thyroid hormone receptors. One long-term goal of our lab is to understand the molecular mechanisms through which the transcriptional activity of NHRs is regulated. Extensive studies in the past few years have revealed that in add

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14

Rouland, Lila. "Étude de la fonction transcriptionnelle de la parkine dans les cancers cérébraux." Electronic Thesis or Diss., Université Côte d'Azur (ComUE), 2019. http://www.theses.fr/2019AZUR6002.

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La parkine, est une protéine responsable de certaines formes autosomiques familiales récessives de la maladie de Parkinson. Elle est principalement considérée comme une ubiquitine ligase E3 mais la parkine se comporte également comme facteur de transcription (FT). En effet, elle réprime trancriptionnellement p53 et module différemment l’expression des presenilines puisqu’elle active PS1 et réprime PS2. A ce jour, trois cibles transcriptionnelles de la parkine p53, PS1 et PS2 ont été identifiées. Il est intéressant de noter que la parkine joue également un rôle dans le cancer en tant que suppre

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15

Du, Tung-Gia. "Role of nuclear RNP assembly in cytoplasmic mRNA localization." Diss., lmu, 2007. http://nbn-resolving.de/urn:nbn:de:bvb:19-76883.

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16

Ribeiro, Maria Margarida. "Genetics of Pinus pinaster Aiton with cytoplasmic and nuclear markers /." Umeå : Swedish Univ. of Agricultural Sciences (Sveriges lantbruksuniv.), 2001. http://epsilon.slu.se/avh/2001/91-576-6061-1.pdf.

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17

Wilkie, Gavin S. "Nuclear export and cytoplasmic localisation of mRNA in Drosophila melanogaster." Thesis, University of Edinburgh, 2001. http://hdl.handle.net/1842/13237.

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This thesis defines the entire pathway of mRNA movement in <i>Drosophila</i> embryonic blastoderm nuclei, from intranuclear sites of synthesis to final sites of localisation in the cytoplasm. It shows that transcription of individual genes can take place in all parts of the nucleus and that genes are not significantly redistributed to new positions when they become active. Furthermore, mRNA export intermediates in the nucleus are evenly distributed, consistent with their movement occurring by unconstrained diffusion within the nucleoplasm. In order to identify proteins involved in intracellula

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18

Östberg, Tove. "Determinants of ligand-induced nuclear receptor activation /." Stockholm : Karolinska institutet, 2004. http://diss.kib.ki.se/2004/91-7349-938-2/.

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19

Sun, Fangzhen. "Nuclear-cytoplasmic interactions during oocyte maturation and early embryogenesis in sheep." Thesis, University of Cambridge, 1989. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.335218.

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20

Soltani, Ali. "Nuclear-Cytoplasmic Interaction Analysis: A Critical Step for Wheat Germplasm Enhancement." Diss., North Dakota State University, 2014. https://hdl.handle.net/10365/27279.

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Wheat (Triticum aestivum) possesses the largest set of available alloplasmic lines in either the plant or animal kingdom. These alloplasmic lines consist of novel combinations of wheat cultivar nuclei and cytoplasm, derived from the Triticum and Aegilops genus. This set of alloplasmic lines provides a unique genetic resource for the enhancement of existing germplasm. The current study was devised to address several aspects of cytoplasm genetics, including cytoplasm evolution and its interaction with the nuclear genome. Initially, the ATP6 gene from 46 different alloplasmic lines was isolated a

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21

Mansén, Anethe. "Gene regulation by nuclear hormone receptors in vivo /." Stockholm, 2003. http://diss.kib.ki.se/2003/91-7349-678-2.

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22

Filatova, Alina. "Mechanism and Control of Nuclear-Cytoplasmic Translocation of the Transporter Regulator RS1." kostenfrei, 2009. http://www.opus-bayern.de/uni-wuerzburg/volltexte/2009/3851/.

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23

Stommel, Jayne M. "The regulation of p53 and MDM2 by nuclear-cytoplasmic shuttling and degradation /." Diss., Connect to a 24 p. preview or request complete full text in PDF format. Access restricted to UC campuses, 2002. http://wwwlib.umi.com/cr/ucsd/fullcit?p3071042.

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24

MAHMOUD, NADY ABDELMOEZ ATTA. "On-chip Electrophoretic Fractionation of Cytoplasmic and Nuclear RNA from Single Cells." Kyoto University, 2019. http://hdl.handle.net/2433/244546.

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25

Carlsson, Jenny. "The mitochondrial influence on nuclear gene expression in cytoplasmic male-sterile Brassica napus /." Uppsala : Dept. of Plant Biology and Forest Genetics, Swedish University of Agricultural Sciences, 2007. http://epsilon.slu.se/200768.pdf.

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26

Navickas, Albertas. "Cytoplasmic control of sense-antisense mRNA pairs in Saccharomyces cerevisiae." Thesis, Paris 6, 2016. http://www.theses.fr/2016PA066381/document.

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Les récentes études transcriptomiques chez divers organismes ont montré que la transcription des gènes convergents peut produire des ARN messagers (ARNm) chevauchants. Ce phénomène a été analysé dans le contexte de l’interférence par ARN (ARNi) nucléaire, et peu d’information existe quant au destin cytoplasmique des messagers 3’ chevauchants ou leur impact sur l’expression des gènes. Dans ce travail, nous avons abordé les conséquences potentielles de l’interaction entre des paires d’ARNm sens-antisens chez Saccharomyces cerevisiae, un organisme modèle naturellement dépourvu de l’ARNi. Nous avo

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27

Johansson, Lotta. "Studies on the atypical orphan receptor SHP /." Stockholm : [Karolinska institutets bibl.], 2001. http://diss.kib.ki.se/2001/91-7349-071-7/.

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28

Vellani, Trina Sehar. "A/a incompatibility in Neurospora crassa : novel suppressors and nuclear incompatibility." Thesis, University of British Columbia, 1991. http://hdl.handle.net/2429/30418.

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The sexual functions of the mating type gene (mt) of Neurospora crassa include specification of mating identity (Shear and Dodge, 1927) and perithecial maturation (Griffiths and DeLange, 1978; Staben and Yanofsky, 1990). The gene also acts as a vegetative incompatibility locus, so that A + a heterokaryons (Beadle and Coonradt, 1944) or A/a duplication strains (Newmeyer and Taylor, 1967) grow poorly or not at all. An intriguing question regarding the mating type gene is this: How does it control both the switch between somatic and meiotic events and heterokaryon incompatibility? Several researc

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29

Knecht, Sharmon M. "PI3K mediates S. aureus invasion leading to peri-nuclear vimentin collapse in human endothelial cells." Virtual Press, 2005. http://liblink.bsu.edu/uhtbin/catkey/1319545.

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Staphylococcus aureus (S. aureus) is a medically important bacterial pathogen associated with many diseases and infections of the respiratory system, wound sites, surgical incisions, and other portals of entry and exit. S. aureus is able to invade cells via mechanisms that have yet to be fully characterized. Vimentin, a protein filament of the animal cell cytoskeleton, and phosphoinositide 3-kinase (PI3K), a family of kinases responsible for initiating several cell signaling events, were found to be associated with S. aureus invasion. Confocal microscopy revealed that the vimentin network in h

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30

Seo, Wooseok. "Functional analysis of murine CD43 shedding : a role for the CD43 cytoplasmic tail in nuclear signalling." Thesis, University of British Columbia, 2008. http://hdl.handle.net/2429/629.

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CD43, a representative of the leukocyte mucin family proteins, is a transmembrane protein highly expressed on most lymphohemopoietic cells and is believed to play a role in the regulation of leukocyte activation and/or migration. CD43 was shown to be proteolytically shed from human cells and high concentrations of soluble CD43 have been found in human plasma. The biological significance of CD43 shedding however remains enigmatic. To study the functional significance of CD43 shedding, we initiated our study by investigating whether CD43 shedding also occurs in the murine system and confirmed u

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31

Winck, Flavia Vischi. "Nuclear proteomics and transcription factor profiling in Chlamydomonas reinhardtii." Phd thesis, Universität Potsdam, 2011. http://opus.kobv.de/ubp/volltexte/2011/5390/.

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The transcriptional regulation of the cellular mechanisms involves many different components and different levels of control which together contribute to fine tune the response of cells to different environmental stimuli. In some responses, diverse signaling pathways can be controlled simultaneously. One of the most important cellular processes that seem to possess multiple levels of regulation is photosynthesis. A model organism for studying photosynthesis-related processes is the unicellular green algae Chlamydomonas reinhardtii, due to advantages related to culturing, genetic manipulation a

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32

Stollar, Rachel. "Fine mapping of the nuclear restorer locus for cytoplasmic male sterility in Brassica napus." Thesis, McGill University, 2001. http://digitool.Library.McGill.CA:80/R/?func=dbin-jump-full&object_id=34014.

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This thesis will discuss the 'Polima' cytoplasmic male sterility (CMS) system (pol) in Brassica napus (Canola) and detailed genetic mapping of the region surrounding restorer gene ( Rfp) for that system This fine mapping of the Rfp region will facilitate efforts to clone the gene that will eventually lead to its characterization. Knowledge of the structure of Rfp will provide insight in the molecular mechanisms governing mitochondrial gene statement as well as pollen production and may lead to the development of alternative methods of pollination control. In addition, it is possible that nucle

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33

Oruganty, Aparna. "Role of the Cytoplasmic Polyadenylation Element Binding Proteins in Neuron: A Dissertation." eScholarship@UMMS, 2013. http://escholarship.umassmed.edu/gsbs_diss/648.

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Genome regulation is an extremely complex phenomenon. There are various mechanisms in place to ensure smooth performance of the organism. Post-transcriptional regulation of gene expression is one such mechanism. Many proteins bind to mRNAs and regulate their translation. In this thesis, I have focused on the Cytoplasmic Polyadenylation Element Binding family of proteins (CPEB1-4); a group of sequence specific RNA binding proteins important for cell cycle progression, senescence, neuronal function and plasticity. CPEB protein binds mRNAs containing a short Cytoplasmic Polyadenylation Element (C

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34

Francisco, Camille. "Role of eEF1A in the Nuclear Export of the VHL Tumour Suppressor Protein." Thèse, Université d'Ottawa / University of Ottawa, 2012. http://hdl.handle.net/10393/23279.

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The ability of proteins to engage in nuclear-cytoplasmic shuttling is required for their proper function. The nuclear export of the von Hippel Lindau (VHL) tumour suppressor protein is necessary for the proteasomal degradation of the hypoxia inducible factor alpha (HIFα). Studies have identified that the nuclear export of VHL and other proteins encoding a Transcription-Dependent Nuclear Export Motif (TD-NEM) is independent of the classical CRM1 nuclear export pathway but requires ongoing transcription. Furthermore, the eukaryotic elongation factor 1 alpha (eEF1A) was identified as a mandatory

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35

Selwood, Simon Peter. "Nuclear-mitochondrial communication in response to mitochondrial stress." Thesis, University of Newcastle Upon Tyne, 1998. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.287824.

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36

White, Hilary Louise. "Transcription in the human #beta# globin locus." Thesis, University of Oxford, 1996. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.337833.

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37

Nordzell, Mariette. "Functional studies on the nuclear receptor Nurr1 /." Stockholm : Karolinska institutet, 2004. http://diss.kib.ki.se/2004/91-7349-867-X/.

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38

Carlsson, Peter. "Nuclear receptors studied by molecular dynamics computer simulations /." Stockholm, 2004. http://diss.kib.ki.se/2004/91-7349-823-8.

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39

Lau, Yue-huen Thomas. "Nuclear transcription factors and hypoxia-inducible genes in chronic liver hypoxia." Click to view the E-thesis via HKUTO, 2005. http://sunzi.lib.hku.hk/hkuto/record/B31939302.

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40

Lau, Yue-huen Thomas, and 劉汝這. "Nuclear transcription factors and hypoxia-inducible genes in chronic liver hypoxia." Thesis, The University of Hong Kong (Pokfulam, Hong Kong), 2005. http://hub.hku.hk/bib/B31939302.

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41

Salat, Canela Clàudia 1989. "Nuclear and non-nuclear roles of the MAP kinase Sty1 on cell cycle, cell polarity and transcription." Doctoral thesis, Universitat Pompeu Fabra, 2020. http://hdl.handle.net/10803/670276.

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Living organisms must respond to changes in their environment in order to overcome stress situations. In Schizosaccharomyces pombe, Sty1 MAP kinase is required to survive to a wide range of environmental stresses. The main outcome of Sty1 activation is the regulation of gene expression through the transcription factor Atf1. Nonetheless, Sty1 also participates in other cellular processes both in a stress-dependent and –independent fashion. In this thesis, I give an insight into some nuclear and non-nuclear functions of Sty1. Specifically, I describe the contribution of cell cycle and cell pola

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42

Lin, Wan-Jung. "The nuclear actions of IGFBP-3." Online access for everyone, 2006. http://www.dissertations.wsu.edu/Thesis/Summer2006/w%5Flin%5F072606.pdf.

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43

Menassa, Rima. "Nuclear-mitochondrial gene interactions and mitochondrial gene expression in Brassica napus." Thesis, National Library of Canada = Bibliothèque nationale du Canada, 1998. http://www.collectionscanada.ca/obj/s4/f2/dsk1/tape10/PQDD_0018/NQ44513.pdf.

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44

Barthelson, Roger, Georgina Lambert, Cheryl Vanier, Ronald Lynch, and David Galbraith. "Comparison of the contributions of the nuclear and cytoplasmic compartments to global gene expression in human cells." BioMed Central, 2007. http://hdl.handle.net/10150/610400.

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BACKGROUND:In the most general sense, studies involving global analysis of gene expression aim to provide a comprehensive catalog of the components involved in the production of recognizable cellular phenotypes. These studies are often limited by the available technologies. One technology, based on microarrays, categorizes gene expression in terms of the abundance of RNA transcripts, and typically employs RNA prepared from whole cells, where cytoplasmic RNA predominates.RESULTS:Using microarrays comprising oligonucleotide probes that represent either protein-coding transcripts or microRNAs (mi

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45

Wargachuk, Richard Burns. "Fine mapping and functional analysis of the radish Rfo nuclear restorer locus." Thesis, McGill University, 2004. http://digitool.Library.McGill.CA:80/R/?func=dbin-jump-full&object_id=81454.

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Cytoplasmic male sterility (CMS) is a widespread, maternally inherited trait that results in an inability of plants to produce functional pollen. The Ogura CMS system originated in radish, but has since been transferred to, and confers male sterility on, plants in the related genus Brassica . A gene which restores male fertility is needed for the Ogura CMS system to be exploited commercially for hybrid seed production in oilseed species such as Brassica napus. The restorer gene Rfo is a dominant radish nuclear gene that restores the male fertility to plants with Ogura cytoplasm. This ge

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46

Radkov, Stoyan Atanassov. "Repression of transcription by the Epstein-Barr virus nuclear antigen (EBNA) 3C." Thesis, Imperial College London, 1999. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.313367.

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47

Ellis, Richard David. "Activation of the transcription factor nuclear factor kappa B in Crohn's disease." Thesis, King's College London (University of London), 2000. https://kclpure.kcl.ac.uk/portal/en/theses/activation-of-the-transcription-factor-nuclear-factor-kappa-b-in-crohns-disease(392a2a2a-0fbd-4cfd-b037-5a0d07d5bc5e).html.

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48

MacLean, Daniel. "Plastid transcriptomics and transcription of nuclear genes for the plastid genetic system." Thesis, University of Cambridge, 2005. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.614945.

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49

Gupta, Pallavi. "Lamin AC mutations and heart: Nuclear envelope damage or disruption of transcription?" Thesis, University of Ottawa (Canada), 2010. http://hdl.handle.net/10393/28596.

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Mutations in the LMNA gene, which encodes the nuclear lamin A/C protein, are implicated in the pathogenesis of over ten phenotypically diverse diseases, including dilated cardiomyopathy (DCM). Two hypotheses have been proposed to explain the tissue specificity of LMNA mutations: 1) Nuclear fragility which may affect to a greater extent mechanically stressed tissues such as cardiac muscle (structural hypothesis); and 2) dysregulation of gene transcription. The objective of this study was to determine which hypothesis explains how LMNA mutations cause DCM. In our cohort of 25 DCM patients, 34%

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50

Adshead, James Michael. "The expression of class III PAX genes in transitional cell carcinoma of the human bladder." Thesis, Imperial College London, 2000. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.248409.

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