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Relevant bibliographies by topics / Cytoprotective agent

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Academic literature on the topic 'Cytoprotective agent'

Author: Grafiati

Published: 2 June 2025

Last updated: 31 July 2025

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Journal articles on the topic "Cytoprotective agent"

1

Marcantonini, Giada, Desirée Bartolini, Linda Zatini, et al. "Natural Cryoprotective and Cytoprotective Agents in Cryopreservation: A Focus on Melatonin." Molecules 27, no. 10 (2022): 3254. http://dx.doi.org/10.3390/molecules27103254.

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Cryoprotective and cytoprotective agents (Cytoprotective Agents) are fundamental components of the cryopreservation process. This review presents the essentials of the cryopreservation process by examining its drawbacks and the role of cytoprotective agents in protecting cell physiology. Natural cryoprotective and cytoprotective agents, such as antifreeze proteins, sugars and natural deep eutectic systems, have been compared with synthetic ones, addressing their mechanisms of action and efficacy of protection. The final part of this article focuses melatonin, a hormonal substance with antioxid

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Bock, Fabian, Khurrum Shahzad, Nathalie Vergnolle, and Berend Isermann. "Activated protein C based therapeutic strategies in chronic diseases." Thrombosis and Haemostasis 111, no. 04 (2014): 610–17. http://dx.doi.org/10.1160/th13-11-0967.

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SummaryActivated protein C (aPC) is a natural anticoagulant and a potent antiinflammatory and cytoprotective agent. At the expense of increased bleeding risk aPC has been used – with some success – in sepsis. The design of cytoprotective-selective aPC variants circumvents this limitation of increased bleeding, reviving the interest in aPC as a therapeutic agent. Emerging studies suggest that aPC’s beneficial effects are not restricted to acute illness, but likewise relevant in chronic diseases, such as diabetic nephropathy, neurodegeneration or wound healing. Epigenetic regulation of gene expr

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Johns, Paul, Suzette L. Pereira, Amanda E. Leonard, et al. "Cytoprotective Agent in Lactobacillus bulgaricus Extracts." Current Microbiology 54, no. 2 (2007): 131–35. http://dx.doi.org/10.1007/s00284-006-0256-6.

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Sikiric, Predrag, Rudolf Rucman, Branko Turkovic, et al. "Novel Cytoprotective Mediator, Stable Gastric Pentadecapeptide BPC 157. Vascular Recruitment and Gastrointestinal Tract Healing." Current Pharmaceutical Design 24, no. 18 (2018): 1990–2001. http://dx.doi.org/10.2174/1381612824666180608101119.

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Years ago, we revealed a novel cytoprotective mediator, stable gastric pentadecapeptide BPC 157, particular anti-ulcer peptide that heals different organs lesions when given as a therapy, native in human gastric juice while maintaining GI-tract mucosal integrity, already tested in trials (ulcerative colitis and now multiple sclerosis). The stomach cytoprotection is the most fundamental concept, stomach cell protection and endothelium protection are largely elaborated, but so far cell, protection and endothelium protection outside of the stomach were not implemented in the therapy. However, hav

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Muddu Krishna, C., J. N. Kolla, Hari Babu Bollikolla, T. Sravan Kumar Reddy, and S. Asha. "Ethyl Gallate: Promising Cytoprotective against HIV-1-Induced Cytopathy and Antiretroviral-Induced Cytotoxicity." Advances in Virology 2023 (July 12, 2023): 1–8. http://dx.doi.org/10.1155/2023/6727762.

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Introduction. HIV-1 infection in cell culture is typically characterized by certain cytopathic effects such as vacuolization of cells and development of syncytia, which further lead to cell death. In addition, the majority of drugs during HIV treatment exhibit serious adverse effects in patients, apart from their beneficial role. During the screening of cytoprotective agents to protect the cells from HIV-1-associated cell death and also drug-associated toxicity, antioxidants from a natural source are assumed to be a choice. A well-known antioxidant, ethyl gallate (EG), was selected for cytopro

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Gundersen, R. Y., P. Vaagenes, T. Breivik, F. Fonnum, and P. K. Opstad. "Glycine - an important neurotransmitter and cytoprotective agent." Acta Anaesthesiologica Scandinavica 49, no. 8 (2005): 1108–16. http://dx.doi.org/10.1111/j.1399-6576.2005.00786.x.

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Hackler, László, Márió Gyuris, Orsolya Huzián, et al. "Enantioselective Synthesis of 8-Hydroxyquinoline Derivative, Q134 as a Hypoxic Adaptation Inducing Agent." Molecules 24, no. 23 (2019): 4269. http://dx.doi.org/10.3390/molecules24234269.

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Hypoxia is a common feature of neurodegenerative diseases, including Alzheimer’s disease that may be responsible for disease pathogenesis and progression. Therefore, the hypoxia-inducible factor (HIF)1 system, responsible for hypoxic adaptation, is a potential therapeutic target to combat these diseases by activators of cytoprotective protein induction. We have selected a candidate molecule from our cytoprotective hydroxyquinoline library and developed a novel enantioselective synthesis for the production of its enantiomers. The use of quinidine or quinine as a catalyst enabled the preparation

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Plotnikov, Evgenii, Innokenty Losenkov, Elena Epimakhova, and Nikolay Bohan. "Protective Effects of Pyruvic Acid Salt Against Lithium Toxicity and Oxidative Damage in Human Blood Mononuclear Cells." Advanced Pharmaceutical Bulletin 9, no. 2 (2019): 302–6. http://dx.doi.org/10.15171/apb.2019.035.

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Purpose: Aim of present work was to study cytoprotective properties of lithium pyruvate, as a prospective pharmacological agent. Pyruvate has a lot of potential benefits due to positive influence on cell metabolism. Lithium is "gold-standard" mood-stabilizer. Combination of both may lead advantages. Methods: Lithium pyruvate was tested as cytoprotector on human blood mononuclears under induced oxidative stress. Cells were obtained from healthy donors and patients with alcoholism. The detection of cell viability, apoptosis and determination of oxidative stress level were conducted by flow cytom

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Kuprash, Liana, Tetyana Panteleymonova, Nina Sykalo, Irina Labunets, and Vladislav Bezrukov. "Nootropic properties of a new combined cytoprotective agent." Issue 3 2022, no. 3 2022 (August 11, 2022): 92–100. http://dx.doi.org/10.47855/jal9020-2022-3-4.

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Medicinal products of nootropic action, which have a positive effect on neurometabolism and normalize memory and intellectual functions, are an important component of complex pharmacotherapy for various neurological and cerebrovascular diseases. The aim of the work was an experimental study of the nootropic activity of the new combined drug Melarginin, which includes 3-(2,2,2-trimethylhydrazinium) propionate (meldonium), L-arginine, and inosine in a fixed ratio. In experiments on female Balb/c mice, it was established that Melarginin in doses of 250 and 500 mg/kg (per os for 14 days) statistic

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Martinel Lamas, D. J., M. B. Nicoud, H. A. Sterle, G. A. Cremaschi, and V. A. Medina. "Histamine: a potential cytoprotective agent to improve cancer therapy?" Cell Death & Disease 6, no. 12 (2015): e2029-e2029. http://dx.doi.org/10.1038/cddis.2015.378.

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Dissertations / Theses on the topic "Cytoprotective agent"

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Ekborn, Andreas. "Cisplatin induced ototoxicity : pharmacokinetics, prediction and prevention /." Stockholm, 2003. http://diss.kib.ki.se/2003/91-7349-721-5.

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Trefry, John Christopher. "The Development of Silver Nanoparticles as Antiviral Agents." Wright State University / OhioLINK, 2011. http://rave.ohiolink.edu/etdc/view?acc_num=wright1307721406.

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Dinh, Hong-Khanh Bao. "Gene expression profiling of thermal induced injury : a drug discovery and development tool for evaluating potential cytoprotective agents for the amelioration of thermal and laser injury to the eye /." Full text (PDF) from UMI/Dissertation Abstracts International, 2001. http://wwwlib.umi.com/cr/utexas/fullcit?p3008316.

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Levi, Micha. "Regional pharmacokinetics of the cytoprotective agent amifostine." 2001. http://catalog.hathitrust.org/api/volumes/oclc/68914919.html.

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Downing, Ashleigh A. "Inter and intra-specific differences in medicinal plant use for the treatment of type II diabetes symptoms by the Cree Elders of Eeyou Istchee (QC)." Thèse, 2010. http://hdl.handle.net/1866/5525.

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Au Canada, nous remarquons une prédominance du diabète de type 2 au sein des communautés autochtones. Une approche ethnobotanique est utilisée en collaboration avec la Nation Crie de Eeyou Istchee afin de déterminer quels traitements à base de plantes peuvent être utilisés pour contrer les différentes conditions qui, collectivement, forment le diabète. Les pharmacopées de deux communautés cries, soit celles de Waskaganish et de Nemaska, ont été établies puis comparées à celles de étudiées antérieurement : communautés Whapmagoostui et Mistissini. Malgré les différences géographiques de ces grou

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Books on the topic "Cytoprotective agent"

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Grdina, David J. Molecular mechanisms in cytoprotection and chemoprevention with ETHYOL (amifostine). Pro-Ed Communications, 1997.

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Filaretova, L. P. (Li︠u︡dmila Pavlovna) and Takeuchi K. (Koji), eds. Cell/tissue injury and cytoprotection/organoprotection in the gastrointestinal tract: Mechanisms, prevention, and treatment. Karger, 2012.

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International Symposium on Gastrointestinal Cytoprotection (3rd 1991 Pécs, Hungary). Cell injury and protection in the gastrointestinal tract: From basic sciences to clinical perspectives : proceedings of the Third International Symposium on Gastrointestinal Cytoprotection, held at Pécs, Hungary, October 7-8, 1991. Edited by Mózsik Gyula. Akadémiai Kiadó, 1993.

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4

Neuroprotection methods and protocols. Humana Press, 2008.

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Borsello, Tiziana. Neuroprotection Methods and Protocols. Humana Press, 2011.

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Neuroprotection Methods and Protocols. Humana Press, 2007.

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Neuroprotection Methods and Protocols. Humana Press, 2007.

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Book chapters on the topic "Cytoprotective agent"

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Minematsu, K. "Combination Therapy with Cytoprotective Agents." In Thrombolytic Therapy in Acute Ischemic Stroke III. Springer Japan, 1995. http://dx.doi.org/10.1007/978-4-431-68459-6_20.

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Barankiewicz, Jerzy, Anne M. Danks, and Paul J. Marangos. "Can Adenosine Deaminase Inhibitors be Cytoprotective Agents?" In Advances in Experimental Medicine and Biology. Springer US, 1998. http://dx.doi.org/10.1007/978-1-4615-5381-6_79.

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Beccarello, A., L. Bortolato, C. Paleari, C. Triches, M. Awasum, and F. Lirussi. "Treatment of Chronic Liver Disease. Do Cytoprotective Agents Interfere with Drug-Metabolizing Activity?" In Cell Injury and Protection in the Gastrointestinal Tract. Springer Netherlands, 1997. http://dx.doi.org/10.1007/978-94-011-5392-8_27.

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4

Fernández-Moriano, Carlos, Elena González-Burgos, and Maria Pilar Gómez-Serranillos. "Lipid Peroxidation and Mitochondrial Dysfunction in Alzheimer's and Parkinson's Diseases: Role of Natural Products as Cytoprotective Agents." In Neuroprotective Natural Products. Wiley-VCH Verlag GmbH & Co. KGaA, 2017. http://dx.doi.org/10.1002/9783527803781.ch6.

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5

Kaur, Sharanjit, Harinder Jot Singh, Sanjay Nayyar, Navpreet Kaur, and Sami Manzoor. "Effectiveness of Trimetazidine, a Cytoprotective Agent in Ischemic Heart Disease." In Technological Innovation in Pharmaceutical Research Vol. 6. Book Publisher International (a part of SCIENCEDOMAIN International), 2021. http://dx.doi.org/10.9734/bpi/tipr/v6/10092d.

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Cardinali, Daniel P. "THE USE OF MELATONIN AS A CHRONOBIOTIC-CYTOPROTECTIVE AGENT IN SLEEP DISORDERS." In The Physiologic Nature of Sleep. PUBLISHED BY IMPERIAL COLLEGE PRESS AND DISTRIBUTED BY WORLD SCIENTIFIC PUBLISHING CO., 2005. http://dx.doi.org/10.1142/9781860947186_0021.

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Mansfield, Caroline S., and Tim Hyndman. "Gastric Cytoprotective Agents." In Canine and Feline Gastroenterology. Elsevier, 2013. http://dx.doi.org/10.1016/b978-1-4160-3661-6.00045-6.

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Webster, Cynthia R. L. "Hepatobiliary Cytoprotective Agents." In Canine and Feline Gastroenterology. Elsevier, 2013. http://dx.doi.org/10.1016/b978-1-4160-3661-6.00046-8.

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Heidari, Reza, and M. Mehdi Ommati. "The Role of Taurine in the Reproductive System: A Focus on Mitochondria-related Mechanisms." In Taurine and the Mitochondrion: Applications in the Pharmacotherapy of Human Diseases. BENTHAM SCIENCE PUBLISHERS, 2023. http://dx.doi.org/10.2174/9789815124484123010012.

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&nbsp;The cytoprotective features of taurine (TAU), including anti-programmed cell death, membrane stabilization, antioxidant, anti-inflammation, osmoregulation, and intracellular calcium homeostasis regulation, have been well addressed in the literature. TAU has also been considered a potent agent for diminishing various xenobiotics caused by physiological and pathophysiological alterations through its antioxidant action in reproductive and non-reproductive organs. Hence, exogenous TAU administration is the topic of many in-depth investigations. Several studies revealed that the antioxida

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"Naturally Occurring Antimutagenic and Cytoprotective Agents." In Biologically Active Natural Products. CRC Press, 1999. http://dx.doi.org/10.1201/9781420048650-14.

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Conference papers on the topic "Cytoprotective agent"

1

Kumar, A., J. Fareed, W. H. Wehrmacher, D. Hoppensteadt, O. Ulutin, and J. M. Walenga. "ENDOTHELIAL FUNCTION MODULATION AND CONTROL OF VASCULAR AND THROMBOTIC DISORDERS: EXPERIMENTAL RESULTS WITH A POLYDEOXY RIBONUCLEOTIDE AGENT DEFIBROTIDE." In XIth International Congress on Thrombosis and Haemostasis. Schattauer GmbH, 1987. http://dx.doi.org/10.1055/s-0038-1643149.

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Numerous approaches with single and multiple drugs modulating protease cascade, platelet function and blood viscosity and to reduce blood lipids to manage thrombotic processes have been tried. Defibrotide, a polydeoxyribonucleotide, (Mr =17,000) offers a new approach to vascular and related thrombotic processes as it acts via modulation of endothelial cell function. We have used a primate model (Macaca mulatta) to study the endogenous action of this agent after the oral (10-25 mg/kg) and intravenous (5-10 mg/kg) administration. This agent produced no effect on clotting tests and ex vivo labora

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Bergmann, I., T. Siepmann, P. KLeinert, G. P. Pescarmona, W. Lôsche, and U. Till. "BENEFIT OF A CELL PENETRABLE SH-COMPOUND FOR PLATELET PREPARATION AND STORAGE." In XIth International Congress on Thrombosis and Haemostasis. Schattauer GmbH, 1987. http://dx.doi.org/10.1055/s-0038-1644596.

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The SH-containing drug 2-mercaptopropionylglycine (2-MPG) which inhibits platelet aggregation in a reversible manner was used as a cytoprotective agent in some experiments on storage of human platelets for transfusion.In vitro-experimentss Blood of 6 healthy volunteers was collected in ACD (control) and in ACD containing 2-MPG. Platelets were stored as PRP at room temperature. Daily, samples of stored platelets were spun down, resuspended in fresh homologous plasma adjusted to pH 7.4, and rewarmed to 37° C for 1 hour, thus simulating in vitro the in vivo-conditions after platelet transfusion.

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