Academic literature on the topic 'D 3.5 UL 2006 B687'

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Journal articles on the topic "D 3.5 UL 2006 B687"

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Rivero, Gustavo A., Dangayach Priti, Jun Zhang, and Marylin Li. "Acute Differentiation Syndrome Is a Biological Consequence Of Treatment With Azanucleoside In Isocitrate Dehydrogenase-1 (IDH-1) and SFR2 mutated Myelodysplasia Derived Acute Myelogenous Leukemia." Blood 122, no. 21 (2013): 4982. http://dx.doi.org/10.1182/blood.v122.21.4982.4982.

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Abstract Background Treatment related toxicity complicates outcome in elderly patients with AML (Estey et al. Blood. 2006). Conventionally, 7+3 induction (anthracycline plus cytarabine) results in Complete Remission rate of about 30%. Regimens with less toxicity, such as 10-days (d) schedule of DAC, seem promising with CR rate of 47% (Blum et al. PNAS. 2010). In secondary MDS derived AML, response prediction could be derived from mutation status in epigenetic modifiers (IDH1, IDH2, DNMT3 A, TET2), transcriptional regulators (RUNX1, CBL), and genes in spliceosome machinery, such as SF3B1 and SR
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2

Niesvizky, R., D. S. Jayabalan, J. R. Furst, et al. "Clarithromycin, lenalidomide and dexamethasone combination therapy as primary treatment of multiple myeloma." Journal of Clinical Oncology 24, no. 18_suppl (2006): 7545. http://dx.doi.org/10.1200/jco.2006.24.18_suppl.7545.

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7545 Background: Lenalidomide (Revlamid [R]) is the leading clinical compound in a new group of drugs called IMiDs. Our group demonstrated that clarithromycin (Biaxin [Bi]) augments tumor mass reduction and improves responses in patients (pts) receiving low-dose thalidomide and/or dexamethasone (D). We report the results of the combination of Bi plus R plus D (BiRD) in newly diagnosed MM. Methods: A phase II trial designed to accrue 50 pts. A 2-stage design rejects a CR rate of < 10% (alt >30%). Between Nov. 2004 and Jan. 2006, 46 pts have been accrued of which 40 pts are eligible for ev
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Gaballa, Sameh, Neil D. Palmisiano, Onder Alpdogan, et al. "Clinical Outcomes of 2-Step Approach to Haploidentical Hematopoietic Stem Cell Transplantation (HSCT): Effects of CD34 Stem Cell Dose in the Setting of a Consistent T-Cell Dose." Blood 124, no. 21 (2014): 1212. http://dx.doi.org/10.1182/blood.v124.21.1212.1212.

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Abstract Introduction: Haploidentical (HI) HSCT offers a curative option to patients (pts) who lack an HLA matched donor. In the 2-step approach, pts receive a relatively large, fixed T-cell dose (2 x 108/kg) followed 2 days later by cyclophosphamide (CY). CY eradicates only the alloreactive T-cells, thus inducing bidirectional tolerance. CD34-selected stem cells are then infused and are not exposed to CY. Unlike T-cell depleted approaches, the 2 step regimen allows for rapid immune recovery and lower infectious complications. Coupled with acceptable GVHD rates, this approach has been associat
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Advani, Anjali S., Holly Gundacker, Marilyn L. Slovak, et al. "Outcome and Prevalence of Hyperdiploidy and Hypodiploidy in Adults with Newly Diagnosed Acute Lymphocytic Leukemia: A SWOG Study." Blood 118, no. 21 (2011): 2555. http://dx.doi.org/10.1182/blood.v118.21.2555.2555.

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Abstract Abstract 2555 High hyperdiploidy is present in 30% of children with acute lymphocytic leukemia (ALL), and is associated with a favorable prognosis. We evaluated pts with newly diagnosed ALL treated on SWOG trials S9400 (1995–2000) and S0333 (2005–2010) to determine the prevalence and prognostic impact of hyperdiploidy in adults with ALL. Additionally, we examined the prognostic impact of hypodiploidy, a feature typically associated with a poor prognosis in children. Methods: One-hundred and eighty-five pts treated on S9400 and S0333 with successful cytogenetic (CG) analysis were inclu
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Fujimura, Yoshihiro, Yumi Yoshii, Masanori Matsumoto, et al. "A Long-Term Phenotype Analysis Of 51 Patients With Upshaw–Schulman Syndrome In Japan, With Special References To Pregnancy and Renal Failure That Requires Hemodialysis." Blood 122, no. 21 (2013): 3545. http://dx.doi.org/10.1182/blood.v122.21.3545.3545.

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Abstract Backgrounds and Aims The classic hallmarks of Upshaw Schulman syndrome (USS) are severe newborn jaundice with a negative Coombs test that requires an exchange transfusion and repeated childhood episodes of thrombocytopenia and microangiopathic hemolytic anemia that are reversed by infusions of fresh frozen plasma. But now, it is well established that USS is a hereditary deficiency in the activity of von Willebrand factor (VWF)-cleaving protease, termed ADAMTS13. The inheritance mode is autosomal recessive, and their parents are usually asymptomatic carriers having one disease-causing
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Thi Hong Nhung, Pham, Do Hanh Nguyen, Bui Thi Yen, Do Thi Le Hang, Vu Thi Thom, and Dinh Doan Long. "Genotyping ITS and matK regions of Hedera nepalensis K. Koch in Vietnam." VNU Journal of Science: Medical and Pharmaceutical Sciences 36, no. 3 (2020). http://dx.doi.org/10.25073/2588-1132/vnumps.4241.

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This study develops procedures for cloning ITS and matK genes on six specimens in order to exploit and conserve the genetic resources of H. nepalensis and evaluate its genetic diversity based on molecular markers. The study methods include DNA extraction from dried leaf samples, amplification of ITS and matK regions using PCR, sequencing and comparing with the sequences on Genbank. The study results include a successfully-established process of cloning ITS and matK genes; successful amplification and sequencing of the ITS and matK regions. The results also show that four samples (N1-N4) were 1
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