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Journal articles on the topic 'D2/D5'

Author: Grafiati

Published: 4 June 2021

Last updated: 1 February 2022

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1

Caiado, José Renato Costa, Francisco Aloízio Fonseca, José Frederico Straggiotti Silva, and Reginaldo da Silva Fontes. "Tratamento de éguas receptoras de embriões visando sua utilização no segundo dia pós-ovulação." Revista Brasileira de Zootecnia 36, no. 2 (2007): 360–68. http://dx.doi.org/10.1590/s1516-35982007000200012.

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Durante as estações de monta de 2001/2002 e 2002/2003, 43 éguas da raça Mangalarga Marchador receptoras de embriões foram tratadas aleatoriamente, via intramuscular, com 200 mg/dia de progesterona oleosa (P4) e 41 éguas da mesma raça receberam 0,044 mg/kg/dia de Altrenogest, aleatoriamente, via oral. Ambos os tratamentos foram efetuados entre D0 (dia da ovulação) e D5. As receptoras foram avaliadas no D2 e, se consideradas aptas, foram inovuladas. Dois grupos de 85 éguas da mesma raça foram utilizados aleatoriamente como controle e não receberam progestágeno, mas foram avaliados e inovulados e

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2

O’Dowd, Brian F., Tuan Nguyen, Xiaodong Ji, and Susan R. George. "D5 dopamine receptor carboxyl tail involved in D5–D2 heteromer formation." Biochemical and Biophysical Research Communications 431, no. 3 (2013): 586–89. http://dx.doi.org/10.1016/j.bbrc.2012.12.139.

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3

Damon, D. H., P. A. D'Amore, and J. A. Wagner. "Nerve growth factor and fibroblast growth factor regulate neurite outgrowth and gene expression in PC12 cells via both protein kinase C- and cAMP-independent mechanisms." Journal of Cell Biology 110, no. 4 (1990): 1333–39. http://dx.doi.org/10.1083/jcb.110.4.1333.

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Nerve growth factor (NGF), acidic fibroblast growth factor (aFGF), and basic fibroblast growth factor (bFGF) promote the survival and differentiation of a variety of peripheral and central neurons. The signal transduction mechanisms that mediate the actions of these factors in neuronal cells are not well understood. We examined the effect of a deficiency in protein kinase C (PKC) and/or cAMP second messenger systems on the actions of NGF, aFGF, and bFGF in the pheochromocytoma (PC12) cell line. Activation of PKC was not required for NGF, aFGF, and bFGF to maximally induce ornithine decarboxyla

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4

Olajide, R. "Pride of Barbados (Delonix regia) seed meal improved the egg quality parameters of black Harco laying hens." Nigerian Journal of Animal Production 48, no. 2 (2021): 79–89. http://dx.doi.org/10.51791/njap.v48i2.2938.

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Nutritional evaluation of Delonix regia seed meal (DRSM) as an alternative energy feed ingredient in replacement of maize was carried out using one hundred and thirty-five (135) black Harco laying hens at twenty weeks old. Five experimental diets were formulated with 0 (60% Maize + 0% DRSM), 25 (45% Maize + 15% DRSM), 50 (30% Maize + 30% DRSM), 75 (15% Maize + 45% DRSM) and 100% (0% Maize + 60% DRSM) replacement of maize with DRSM weight for weight, designated as D1, D2, D3, D4 and D5 respectively. The experimental birds were randomly assigned to 5 experimental diets in a Completely Randomized

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Yang, Zhiwei, Laureano D. Asico, Peiying Yu, et al. "D5 dopamine receptor regulation of reactive oxygen species production, NADPH oxidase, and blood pressure." American Journal of Physiology-Regulatory, Integrative and Comparative Physiology 290, no. 1 (2006): R96—R104. http://dx.doi.org/10.1152/ajpregu.00434.2005.

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Activation of D1-like receptors (D1 and/or D5) induces antioxidant responses; however, the mechanism(s) involved in their antioxidant actions are not known. We hypothesized that stimulation of the D5 receptor inhibits NADPH oxidase activity, and thus the production of reactive oxygen species (ROS). We investigated this issue in D5 receptor-deficient (D5−/−) and wild-type (D5+/+) mice. NADPH oxidase protein expression (gp91phox, p47phox, and Nox 4) and activity in kidney and brain, as well as plasma thiobarbituric acid-reactive substances (TBARS) were higher in D5−/− than in D5+/+ mice. Further

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Saxena, Neha, Asha Dhawan, Meera D. Ansal, and Vikas Phulia. "Effect of plant and animal protein sources on the growth, gonadal maturity and proximate composition of Labeo rohita (Hamilton, 1822)." Journal of Applied and Natural Science 7, no. 2 (2015): 631–38. http://dx.doi.org/10.31018/jans.v7i2.657.

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The aim of the present study was to evaluate the effect of plant and animal sources in the diet of Labeo rohita with an overall goal of gaining sustainable fish and egg production. Fishes with an initial weight of 310-323 g were fed with five different isocaloric (3Kcalg-1) diets viz. D1 ( control diet- 30% rice bran + 70% groundnut meal), D2 (30% rice bran + 50% groundnut meal + 20% fish meal), D3 (30% rice bran + 50% groundnut meal + 20% mustard meal), D4 (30% rice bran + 30% groundnut meal + 20% mustard meal + 20 % fish meal) and D5 (30% rice bran + 30% soybean meal + 20% mustard meal + 20

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7

Werstiuk, Nick Henry, and George Timmins. "Protium–deuterium exchange of styrenes in dilute acid at elevated temperatures." Canadian Journal of Chemistry 66, no. 9 (1988): 2309–12. http://dx.doi.org/10.1139/v88-366.

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A modified high temperature – dilute acid method is used to synthesize phenylethene-2,2-d2 ("styrene-2,2-d2") (1b), 2-phenylpropene-1,1,3,3,3-d5 ("α-trideuteriomethylstyrene-2,2-d5") (2b), and E-1-phenylpropene-2-d ("trans-β-methylstyrene-2-d") (3b) from phenylethene ("styrene") (1a), 2-phenylpropene ("α-methylstyrene") (2a), and E-1-phenylpropene ("trans-β-methylstyrene") (3a), respectively. The deuteriated substitution product E-1,3-diphenyl-1-butene-2,4,4,4-d4 (4b) is also obtained from 1a. Labelled substitution products 1,3,3-tri-trideuteriomethyl-1-phenylindane-2,2-d11 (5b), 4-trideuterio

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Komba, Shiro, Eiichi Kotake-Nara та Wakako Tsuzuki. "Simultaneous Synthesis of Vitamins D2, D4, D5, D6, and D7 from Commercially Available Phytosterol, β-Sitosterol, and Identification of Each Vitamin D by HSQC NMR". Metabolites 9, № 6 (2019): 107. http://dx.doi.org/10.3390/metabo9060107.

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We succeeded in simultaneously synthesizing the vitamin D family, vitamins D2, D4, D5, D6, and D7, from β-sitosterol, which is sold as a commercially available reagent from Tokyo Chemical Industry Co., Ltd. It is officially sold as a mixture of four phytosterols {β-sitosterol (40–45%), campesterol (20–30%), stigmasterol, and brassicasterol}. Owing to this, we anticipated that, using this reagent, various vitamin D analogs could be synthesized simultaneously. We also synthesized vitamin D3 from pure cholesterol and analyzed and compared all vitamin D analogs (D2, D3, D4, D5, D6, and D7) by HSQC

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Owen, L. J., and B. G. Keevil. "Testosterone measurement by liquid chromatography tandem mass spectrometry: the importance of internal standard choice." Annals of Clinical Biochemistry: International Journal of Laboratory Medicine 49, no. 6 (2012): 600–602. http://dx.doi.org/10.1258/acb.2012.012037.

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Background Testosterone measurement by liquid chromatography tandem mass spectrometry (LC-MS/MS) is well accepted as the preferred technique for the analysis of testosterone. Variation is seen between assays and is likely to be due to method differences. One area of inconsistency among assays is the choice of internal standard. We investigated the effects of three internal standards. Methods Testosterone with two deuterium (D2), five deuterium (D5) and three carbon 13 enrichment (C13) were separately assessed. Samples were extracted using ether following the addition of 10 μL of internal stand

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VERMA, AJAY. "Wheat genotypes evaluated for GxE interactions in Central Zone of the country by AMMI analysis." Annals of Plant and Soil Research 23, no. 3 (2021): 341–45. http://dx.doi.org/10.47815/apsr.2021.10081.

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Highly significant effects of environments, GxE interaction and genotypes were observed for cropping years 2017-18 and 2018-19. Further analysis of interactions sum of squares bifurcated into seven significant multiplicative interactions principal components to assess the performances of genotypes as per AMMI based measures. For the first year of study wheat genotypes (G5, G6, G7) had top ranked by EV2, D2, ASV, ASV1 and ASTAB2 measures. MASV & MASV1 pointed towards G7, G8, G6 wheat genotypes. Association among these measures displayed graphically in a biplot analysis. Largest cluster comp

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Hodder, AN, KA Holland, and ID Rae. "Thermal-Degradation of Polymers. I. Integrity of Monomer Derived From Thermal-Degradation of Poly(Methyl Methacrylate) and Poly(Methacrylonitrile)." Australian Journal of Chemistry 39, no. 11 (1986): 1883. http://dx.doi.org/10.1071/ch9861883.

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A random copolymer of methyl methacrylate and its (D5)analogue has been used to show that thermal degradation of the polymer regenerates the original monomer units. A similar result has been obtained for poly( methacrylonitrile ). In each case, thermal degradation at 200° produced mainly the (D0)- and (D5)-species, while at higher temperatures some (D2)- and (D3)-ions were observed in the mass spectrum of the recovered monomer.

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12

Ladines, Cecilia A., Chunyu Zeng, Laureano D. Asico, et al. "Impaired renal D1-like and D2-like dopamine receptor interaction in the spontaneously hypertensive rat." American Journal of Physiology-Regulatory, Integrative and Comparative Physiology 281, no. 4 (2001): R1071—R1078. http://dx.doi.org/10.1152/ajpregu.2001.281.4.r1071.

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D1-like (D1, D5) and D2-like (D2, D3, D4) dopamine receptors interact in the kidney to produce a natriuresis and a diuresis. Disruption of D1 or D3 receptors in mice results in hypertension that is caused, in part, by a decreased ability to excrete an acute saline load. We studied D1-like and D2-like receptor interaction in anesthetized spontaneously hypertensive rats (SHR) by the intrarenal infusion of Z-1046 (a novel dopamine receptor agonist with rank order potency of D3≥D4>D2>D5>D1). Z-1046 increased glomerular filtration rate (GFR), urine flow, and sodium excretion in normotensiv

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13

Sinzato, Yuri K., Eduardo Klöppel, Carolina A. Miranda, et al. "Comparison of streptozotocin-induced diabetes at different moments of the life of female rats for translational studies." Laboratory Animals 55, no. 4 (2021): 329–40. http://dx.doi.org/10.1177/00236772211001895.

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Animal models are widely used for studying diabetes in translational research. However, methods for induction of diabetes are conflicting with regards to their efficacy, reproducibility and cost. A comparison of outcomes between the diabetic models is still unknown, especially full-term pregnancy.To understand the comparison, we analyzed the streptozotocin (STZ)-induced diabetes at three life-different moments during the neonatal period in Sprague–Dawley female rats: at the first (D1), second (D2) and fifth (D5) day of postnatal life. At adulthood (90 days; D90), the animals were submitted to

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14

Inyang, U. A., and T. O. Ososanya. "Reduction of faecal shedding of parasites in West African dwarf bucks fed yeast and Lactobacillus acidophilus." Nigerian Journal of Animal Production 44, no. 3 (2021): 384–92. http://dx.doi.org/10.51791/njap.v44i3.659.

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Ruminants serve as reservoirs of pathogenic microorganisms and their faecal shedding forms the vehicle of entry into human food chain which in turn causes food borne diseases. Usually drugs and live vaccines are the main control measures; however, due to increasing concerns of resistance and residues in meat with prophylactic drug use and the high cost of vaccines, alternative control methods are needed. The aim of this study was to determine if administration of probiotics could influence the shedding of faecal pathogenic bacteria and parasites/helminthes from WAD goats. In a completely rando

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15

Khan, Nangial, Yingchun Han, Fangfang Xing, et al. "Plant Density Influences Reproductive Growth, Lint Yield and Boll Spatial Distribution of Cotton." Agronomy 10, no. 1 (2019): 14. http://dx.doi.org/10.3390/agronomy10010014.

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The number of cotton plants grown per unit of ground area has gained attention due to the high prices of inputs and lower production. Cotton yield per unit of area in Henan province has been stagnant in the last few years. The objectives of this study were to investigate cotton growth, yield, boll spatial distribution and biomass accumulation using different plant densities at cultivation and to find out the optimal plant density. A 2-year field experiment was conducted in a randomized complete block design under six plant densities (D1, 15,000; D2, 33,000; D3, 51,000; D4, 69,000; D5, 87,000 a

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16

Sunahara, Roger K., Philip Seeman, Hubert H. M. Van Tol, and Hyman B. Niznik. "Dopamine Receptors and Antipsychotic Drug Response." British Journal of Psychiatry 163, S22 (1993): 31–38. http://dx.doi.org/10.1192/s000712500029257x.

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Dopamine receptors have been divided into two major types – D1 and D2 – based primarily on pharmacological and biochemical criteria. Recent advances in the molecular biology of the dopamine receptor system have allowed the identification and characterisation of at least five distinct neuronal dopamine receptor genes (D1 to D5). These genes encode dopamine receptors belonging to the D1 receptor family, termed D1 and D5, and three D2-like receptors, termed D2, D3 and D4. These receptors are distinguished on the basis of their primary structure, chromosomal location, mRNA size and tissue distribu

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MISSALE, CRISTINA, S. RUSSEL NASH, SUSAN W. ROBINSON, MOHAMED JABER, and MARC G. CARON. "Dopamine Receptors: From Structure to Function." Physiological Reviews 78, no. 1 (1998): 189–225. http://dx.doi.org/10.1152/physrev.1998.78.1.189.

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Missale, Cristina, S. Russel Nash, Susan W. Robinson, Mohamed Jaber, and Marc G. Caron. Dopamine Receptors: From Structure to Function. Physiol. Rev. 78: 189–225, 1998. — The diverse physiological actions of dopamine are mediated by at least five distinct G protein-coupled receptor subtypes. Two D1-like receptor subtypes (D1 and D5) couple to the G protein Gs and activate adenylyl cyclase. The other receptor subtypes belong to the D2-like subfamily (D2 , D3 , and D4) and are prototypic of G protein-coupled receptors that inhibit adenylyl cyclase and activate K+ channels. The genes for the D1 a

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18

E. O, Agboola, Adebayo I. A, and Babalola B. T. "Growth Performance of Heteroclarias Juveniles Fed Graded Levels of Autoclaved Castor Seed (Ricinus communis L.) Cake Based Diets." International Journal of Aquaculture Research and Development 1, no. 2 (2020): 1–12. http://dx.doi.org/10.14302/issn.2691-6622.ijar-20-3312.

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An 84 day feeding trial was conducted on the juveniles (42.51±0.09g) of hybrid catfish, Heteroclarias, in order to evaluate the nutritional potential of 30 minutes autoclaved castor seed cake isonitrogenous (40% crude protein) and isocaloric (3212Kcal/Kg) diets replacing soybean meal at 0, 12.5, 25, 37.5 and 50%, the diets being designated D1, D2, D3, D4 and D5 respectively. Prior to this, the castor seeds (Ricinus communis L.), ZiboCastor No. 3 variety, collected from Ado-Ekiti metropolis, Nigeria were subjected to 0, 20, 30 and 40 minutes autoclaved at 121oC, dehauled, grounded, oil extracte

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O'Sullivan, Gerard J., Anthony Kinsella, David R. Sibley, Orna Tighe, David T. Croke, and John L. Waddington. "Ethological resolution of behavioural topography and D1-like versus D2-like agonist responses in congenic D5 dopamine receptor mutants: Identification of D5:D2-like interactions." Synapse 55, no. 4 (2005): 201–11. http://dx.doi.org/10.1002/syn.20107.

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Recacha, Rosario, David Jiménez, Li Tian, Román Barredo, Carl G. Gahmberg, and José M. Casasnovas. "Crystal structures of an ICAM-5 ectodomain fragment show electrostatic-based homophilic adhesions." Acta Crystallographica Section D Biological Crystallography 70, no. 7 (2014): 1934–43. http://dx.doi.org/10.1107/s1399004714009468.

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Intercellular cell adhesion molecule-5 (ICAM-5) is a member of the ICAM subfamily that is exclusively expressed in the telencephalon region of the brain. The crystal structure of the four most N-terminal glycosylated domains (D1–D4) of ICAM-5 was determined in three different space groups and the D1–D5 fragment was modelled. The structures showed a curved molecule with two pronounced interdomain bends between D2 and D3 and between D3 and D4, as well as some interdomain flexibility. In contrast to ICAM-1, ICAM-5 has patches of positive and negative electrostatic charge at D1–D2 and at D3–D5, re

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21

Yang, Hong-Wei, Li-Jun Zhou, Neng-Wei Hu, Wen-Jun Xin, and Xian-Guo Liu. "Activation of Spinal D1/D5 Receptors Induces Late-Phase LTP of C-Fiber–Evoked Field Potentials in Rat Spinal Dorsal Horn." Journal of Neurophysiology 94, no. 2 (2005): 961–67. http://dx.doi.org/10.1152/jn.01324.2004.

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Long-term potentiation (LTP) of C-fiber–evoked field potentials in spinal dorsal horn may be relevant to pathological pain. Our previous work has shown that the late phase of the spinal LTP is protein synthesis–dependent. Considerable evidence has accumulated that dopamine D1/D5 receptors are important for late-phase LTP in hippocampus. In this study, the role of D1/D5 receptors in LTP of C-fiber–evoked field potentials in spinal dorsal horn was evaluated in urethan-anesthetized Sprague-Dawley rats. We found the following. 1) Spinal application of SKF 38393, a D1/D5 receptor agonist, induced a

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Awenowicz, Patrick W., and Linda L. Porter. "Local Application of Dopamine Inhibits Pyramidal Tract Neuron Activity in the Rodent Motor Cortex." Journal of Neurophysiology 88, no. 6 (2002): 3439–51. http://dx.doi.org/10.1152/jn.00078.2002.

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Cortical neurons respond in a variety of ways to locally applied dopamine, perhaps because of the activation of different receptors within or among subpopulations of cells. This study was conducted to assess the effects of dopamine and the receptor subtypes that mediate the responses of a specific population of neurons, the pyramidal tract neurons (PTNs) in the rodent motor cortex. The specific subfamilies of dopamine receptors expressed by PTNs also were determined. PTNs were identified by antidromic stimulation in intact animals. Extracellular recordings of their spontaneous activity and glu

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Petrik, Attila, Barbara Beke, László Fodor, and Réka Lukács. "Cenozoic structural evolution of the southwestern Bükk Mts. and the southern part of the Darnó Deformation Belt (NE Hungary)." Geologica Carpathica 67, no. 1 (2016): 83–104. http://dx.doi.org/10.1515/geoca-2016-0005.

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Abstract Extensive structural field observations and seismic interpretation allowed us to delineate 7 deformation phases in the study area for the Cenozoic period. Phase D1 indicates NW–SE compression and perpendicular extension in the Late Oligocene–early Eggenburgian and it was responsible for the development of a wedge-shaped Paleogene sequence in front of north-westward propagating blind reverse faults. D2 is represented by E–W compression and perpendicular extension in the middle Eggenburgian–early Ottnangian. The D1 and D2 phases resulted in the erosion of Paleogene suites on elevated hi

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Morais, R. C. L., G. A. Dutra, J. P. Oliveira, F. C. V. L. Fonseca, C. F. P. M. Carvalho, and J. C. F. Jacob. "Ultrassonografia testicular no modo color Doppler∕ espectral e avaliação andrológica de garanhões tratados com gonadotrofina coriônica humana (hCG) em diferentes estações do ano." Arquivo Brasileiro de Medicina Veterinária e Zootecnia 72, no. 4 (2020): 1137–44. http://dx.doi.org/10.1590/1678-4162-11437.

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RESUMO Utilizaram-se quatro garanhões nos meses de janeiro, abril, julho e outubro de 2016, em dois protocolos, em que: GI (n=4; 5mL de solução salina, i.v.) e GII (n=4; 5000UI de hCG, i.v.) e subdividiram-se esses protocolos em ciclos (C1 e C2), seguindo o esquema crossover, sendo: CI=animais 1 (GI) e 2 (GII), avaliados nos dias D1, D3 e D5, e animais 3 (GI) e 4 (GII), em D2, D4 e D6; CII= animais 1 (GII) e 2 (GI), em D1, D3, D5, e animais 3 (GII) e 4 (GI), em D2, D4 e D6. Realizou-se o tratamento em D1 e D2 de cada ciclo e a ultrassonografia testicular no modo color Doppler e Doppler espectr

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So, Christopher H., Vaneeta Verma, Mohammad Alijaniaram, et al. "Calcium Signaling by Dopamine D5 Receptor and D5-D2 Receptor Hetero-Oligomers Occurs by a Mechanism Distinct from That for Dopamine D1-D2 Receptor Hetero-Oligomers." Molecular Pharmacology 75, no. 4 (2009): 843–54. http://dx.doi.org/10.1124/mol.108.051805.

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Ma’rifah, Faridlotul, Miftahul Rohmah Saputri, Agoes Soegianto, Bambang Irawan, and Trisnadi Widyaleksono Catur Putranto. "The Change of Metallothionein and Oxidative Response in Gills of the Oreochromis niloticus after Exposure to Copper." Animals 9, no. 6 (2019): 353. http://dx.doi.org/10.3390/ani9060353.

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In the present study, we investigated the effects of waterborne copper (Cu) on the levels of metallothionein (MT) and malondialdehyde (MDA), as well as activities of superoxide dismutase (SOD) and catalase (CAT) in gills of cichlid fish Oreochromis niloticus. The Cu concentrations in gills were measured using an atomic absorption spectrometer. The sandwich-ELISA was used to measure MT, SOD, CAT, and MDA. The Cu concentrations in gills of fish that were exposed to 1, 5, and 10 mg Cu/L were significantly increased at day 1 (D1), then gradually decreased starting from D2, and reaches the similar

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Galvan, Adriana, Xing Hu, Karen S. Rommelfanger, et al. "Localization and function of dopamine receptors in the subthalamic nucleus of normal and parkinsonian monkeys." Journal of Neurophysiology 112, no. 2 (2014): 467–79. http://dx.doi.org/10.1152/jn.00849.2013.

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The subthalamic nucleus (STN) receives a dopaminergic innervation from the substantia nigra pars compacta, but the role of this projection remains poorly understood, particularly in primates. To address this issue, we used immuno-electron microscopy to localize D1, D2, and D5 dopamine receptors in the STN of rhesus macaques and studied the electrophysiological effects of activating D1-like or D2-like receptors in normal and 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP)-treated parkinsonian monkeys. Labeling of D1 and D2 receptors was primarily found presynaptically, on preterminal axons

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Eroles, Pilar, Isabel Benet, Isabel Marugan, Ana Belen Teruel, Carlos Solano, and Maria Jose Terol. "Study of the Expression of Angiogenic Factors and Dopaminergic Receptors: Correlation with ZAP70, CD38 and the Mutational State in Chronic Lymphocytic Leukaemia (CLL)." Blood 108, no. 11 (2006): 4928. http://dx.doi.org/10.1182/blood.v108.11.4928.4928.

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Abstract The angiogenesis is a well known process implicate in the progression of CLL. In this disease has been described an increase of angiogenic and pro-angiogenic factors in serum and angiogenic receptors in B cells, mainly in advances stages. Recently had been known that the agonist of the dopaminergic receptor D2 can inhibit the tumour growth and a possible mechanism mediator is the internalization of VEGFR-2. The aim of this work had been to analyze the expression of the dopaminergic receptors (D1, D2, D3, D4 and D5), the angiogenic receptors and its correlation with the main biological

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Vargas-Ceballos, Manuel A., Daniel Badillo-Zapata, Olimpia Chong-Carrillo, Jesús T. Ponce-Palafox, Luis Héctor Hernández-Hernández, and Fernando Vega-Villasante. "Intake of different food sources in the first zoeae stages of Macrobrachium tenellum (Decapoda: Palaemonidae)." Latin American Journal of Aquatic Research 48, no. 1 (2020): 156–61. http://dx.doi.org/10.3856/vol48-issue1-fulltext-2344.

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The objective of this work was to assess the acceptance of live and inert food by Macrobrachium tenellum during the early larval stages. The larvae were obtained by collecting wild ovigerous females in the Ameca River in the State of Jalisco, Mexico. Eight treatments (diets) were used to feed the larvae: D1, control (fasting); D2, micro-pulverized food (Purina®); D3, living, newly hatched nauplii of Artemia franciscana (INVE®, Salt Lake City, Utah, USA); D4, commercial paste containing microalgae (Instant Algae Rotifer Diet®); D5, water extracted from a biofloc system; D6, cooked egg yolk; D7,

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Kim, Yongju, Jeong Eun Park, Jeong Jae Wie, Su Geun Yang, Don Haeng Lee, and Young-Joo Jin. "Effects of Helix Geometry on Magnetic Guiding of Helical Polymer Composites on a Gastric Cancer Model: A Feasibility Study." Materials 13, no. 4 (2020): 1014. http://dx.doi.org/10.3390/ma13041014.

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This study investigates the effects of soft-robot geometry on magnetic guiding to develop an efficient helical mediator on a three-dimensional (3D) gastric cancer model. Four different magnetically active helical soft robots are synthesized by the inclusion of 5-μm iron particles in polydimethylsiloxane matrices. The soft robots are named based on the diameter and length (D2-L15, D5-L20, D5-L25, and D5-L35) with samples having varied helical pitch and weight values. Then, the four samples are tested on a flat surface as well as a stomach model with various 3D wrinkles. We analyze the underlyin

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Rappaport, M. S., S. C. Sealfon, A. Prikhozhan, G. W. Huntley, and J. H. Morrison. "Heterogeneous distribution of D1, D2 and D5 receptor mRNAs in monkey striatum." Brain Research 616, no. 1-2 (1993): 242–50. http://dx.doi.org/10.1016/0006-8993(93)90215-9.

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Yamamoto, Kei, Romain Fontaine, Catherine Pasqualini, and Philippe Vernier. "Classification of Dopamine Receptor Genes in Vertebrates: Nine Subtypes in Osteichthyes." Brain, Behavior and Evolution 86, no. 3-4 (2015): 164–75. http://dx.doi.org/10.1159/000441550.

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Dopamine neurotransmission regulates various brain functions, and its regulatory roles are mediated by two families of G protein-coupled receptors: the D1 and D2 receptor families. In mammals, the D1 family comprises two receptor subtypes (D1 and D5), while the D2 family comprises three receptor subtypes (D2, D3 and D4). Phylogenetic analyses of dopamine receptor genes strongly suggest that the common ancestor of Osteichthyes (bony jawed vertebrates) possessed four subtypes in the D1 family and five subtypes in the D2 family. Mammals have secondarily lost almost half of the ancestral dopamine

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Gava, Emanuel, Marcos V. Faria, Welton L. Zaluski, Jocimar C. Rosa, Elida AP Paiva, and Nathany R. Chiquito. "Agronomic performance of experimental super sweet corn hybrids." Horticultura Brasileira 39, no. 2 (2021): 199–204. http://dx.doi.org/10.1590/s0102-0536-20210211.

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ABSTRACT Super sweet is classified as a special type of corn, due to the presence of genes which promote sugar accumulation in grains, significantly reducing starch content in the endosperm. This study aimed to evaluate the agronomic performance of experimental super sweet corn hybrids, carrying the gene shrunken-2, in order to identify and select promising genotypes for Southern Brazil. The experiments were carried out in two sowing seasons in 2017/18, in the experimental field of UNICENTRO, Guarapuava-PR, Brazil. Thirty-two experimental hybrids resulting from an 8x4 partial diallel among sup

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Gorelova, Natalia, Jeremy K. Seamans, and Charles R. Yang. "Mechanisms of Dopamine Activation of Fast-Spiking Interneurons That Exert Inhibition in Rat Prefrontal Cortex." Journal of Neurophysiology 88, no. 6 (2002): 3150–66. http://dx.doi.org/10.1152/jn.00335.2002.

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Prefrontal cortical dopamine (DA) modulates pyramidal cell excitability directly and indirectly by way of its actions on local circuit GABAergic interneurons. DA modulation of interneuronal functions is implicated in the computational properties of prefrontal networks during cognitive processes and in schizophrenia. Morphologically and electrophysiologically distinct classes of putative GABAergic interneurons are found in layers II-V of rat prefrontal cortex. Our whole cell patch-clamp study shows that DA induced a direct, TTX-insensitive, reversible membrane depolarization, and increased the

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Mills, Kayla M., Tabitha Steckler, Megan Bock, Amanda M. Minton, Steve Terlouw, and Kara R. Stewart. "PSII-20 Effect of mixing of extended boar semen using a bulk semen delivery system after 2 and 5 days in storage." Journal of Animal Science 97, Supplement_2 (2019): 234. http://dx.doi.org/10.1093/jas/skz122.412.

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Abstract With the increase in utilization of bulk semen delivery systems, the objective of this study was to determine whether differences in semen quality exist from mixing stored bulk semen. Semen with motility and normal morphology >75% were used to create 4, 70-dose and 4, 35-dose bulk semen bags. Semen was cooled and transported 235 miles. On d2 or d5, a bag was mixed and hung for 15 min. Doses were removed every 2 minutes. One 70-dose (70M) and one 35-dose bag (35M) were mixed every 5th dose, while the remaining 70-dose (70NM) and 35-dose (35NM) bags were not mixed. Doses were weighed

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Rentziou, Gianna, Katerina Saltiki, Efstathios Manios, et al. "Effects of Recombinant Human Thyrotropin Administration on 24-Hour Arterial Pressure in Female Undergoing Evaluation for Differentiated Thyroid Cancer." International Journal of Endocrinology 2014 (2014): 1–8. http://dx.doi.org/10.1155/2014/270213.

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Objective.Thyroid-stimulating-hormone (TSH) receptors are expressed in endothelial cells. We investigated whether elevated TSH levels after acute recombinant TSH (rhTSH) administration may result in alterations in blood pressure (BP) in premenopausal women with well-differentiated thyroid carcinoma (DTC).Designs.Thirty euthyroid DTC female patients were evaluated by rhTSH stimulation test (mean age40.4±8.6years). A 24 h ambulatory systolic and diastolic blood pressure (SBP, DBP) monitoring (24 hr ABPM) was performed on days 2-3(D2-3). TSH was measured on day 1(D1), day 3(D3), and day 5(D5). Ce

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Eboibi, B. E., K. O. Adiotomre, F. Onobrudu, and E. Osioh. "Anaerobic Digestion of Cassava (Manihot Esculenta) Waste: Effects of Inoculum on Biogas Production Rate." Nigerian Journal of Environmental Sciences and Technology 4, no. 2 (2020): 411–20. http://dx.doi.org/10.36263/nijest.2020.02.0226.

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In this paper, cow manure fluid was used as inoculums to investigate biogas production rate from anaerobic digestion of cassava peel at mesophilic temperature (280C). The anaerobic experiment was conducted using six batch digesters (D1, D2, D3, D4, D5 and D6) each of 20L capacity for 40-day hydraulic retention. Each digester, was loaded with 5kg of cassava peel (CP) and 0%, 10%, 20%, 30%, 40% and 50% of inoculum to CP. Hashimoto model was used to obtain the digestion kinetic parameters. The results of the study showed that inoculums influenced the rate of biogas production, showing variations

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Al-Siweedi, Saif Yousif Abdullah, P. Nambiar, P. Shanmuhasuntharam, and W. C. Ngeow. "Gaining Surgical Access for Repositioning the Inferior Alveolar Neurovascular Bundle." Scientific World Journal 2014 (2014): 1–11. http://dx.doi.org/10.1155/2014/719243.

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This study is aimed at determining anatomical landmarks that can be used to gain access to the inferior alveolar neurovascular (IAN) bundle. Scanned CBCT (i-CAT machine) data of sixty patients and reconstructions performed using the SimPlant dental implant software were reviewed. Outcome variables were the linear distances of the mandibular canal to the inferior border and the buccal cortex of the mandible, measured immediately at the mental foramen (D1) and at 10, 20, 30, and 40 mm (D2–D5) distal to it. Predictor variables were age, ethnicity, and gender of subjects. Apicobasal assessment of

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Kotake-Nara, Eiichi, Shiro Komba, and Megumi Hase. "Uptake of Vitamins D2, D3, D4, D5, D6, and D7 Solubilized in Mixed Micelles by Human Intestinal Cells, Caco-2, an Enhancing Effect of Lysophosphatidylcholine on the Cellular Uptake, and Estimation of Vitamins D’ Biological Activities." Nutrients 13, no. 4 (2021): 1126. http://dx.doi.org/10.3390/nu13041126.

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Vitamins D have various biological activities, as well as intestinal calcium absorption. There has been recent concern about insufficient vitamin D intake. In addition to vitamins D2 and D3, there are lesser-known vitamins D4–D7. We synthesized vitamins D5–D7, which are not commercially available, and then evaluated and compared the mixed micelles-solubilized vitamins D uptake by Caco-2 cells. Except for vitamin D5, the uptake amounts of vitamins D4–D7 by differentiated Caco-2 cells were similar to those of vitamins D2 and D3. The facilitative diffusion rate in the ezetimibe inhibited pathway

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Snoeck, P. P. N., M. Henry, and M. I. V. Melo. "Efeito de diferentes diluidores sobre a viabilidade espermática pós-descongelação de sêmen eqüino." Arquivo Brasileiro de Medicina Veterinária e Zootecnia 59, no. 1 (2007): 56–64. http://dx.doi.org/10.1590/s0102-09352007000100010.

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Estudou-se o efeito de diferentes concentrações de gema de ovo, açúcares e tampões nos diluidores sobre a viabilidade espermática pós-descongelação de sêmen eqüino. Os diluidores foram: D1 = 10% de gema de ovo e acréscimo de 50% de lactose e glicose-EDTA em relação ao D5; D2= 10% de gema de ovo e redução de 50% de lactose e glicose-EDTA em relação ao D5; D3= 20% de gema de ovo e acréscimo de 50% de lactose e glicose-EDTA em relação ao D5; D4= 20% de gema de ovo e redução de 50% de lactose e glicose-EDTA em relação ao D5; D5= 20% de gema de ovo e composição de lactose e glicose-EDTA segundo Mar

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Kollipara, K. P., R. J. Singh, and T. Hymowitz. "Genomic diversity in aneudiploid (2n = 38) and diploid (2n = 40) Glycine tomentella revealed by cytogenetic and biochemical methods." Genome 36, no. 3 (1993): 391–96. http://dx.doi.org/10.1139/g93-054.

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Of the 15 perennial species of the subgenus Glycine Willd., G. tomentella Hayata is unique in that it has four cytotypes (2n = 38, 40, 78, and 80) and a wide range of geographical distributions. The objective of this study was to uncover the genomic diversity among accessions of aneudiploid (2n = 38) and diploid (2n = 40) G. tomentella based on crossability rate, hybrid seed and seedling viability, meiotic chromosome pairing of F1 hybrids, and seed protein and protease inhibitor profiles. Aneudiploid and diploid G. tomentella accessions were divided into two (D1 and D2) and three [D3(A,B,C), D

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Singh, Ram J., Krishna P. Kollipara, and Theodore Hymowitz. "The genomes of Glycine canescens F.J. Herm., and G. tomentella Hayata of Western Australia and their phylogenetic relationships in the genus Glycine Willd." Genome 41, no. 5 (1998): 669–79. http://dx.doi.org/10.1139/g98-051.

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A multidisciplinary approach is an extremely powerful tool for determining genomic diversity and establishing genomic relationships within and among species. This study used cytogenetics and a molecular method (ITS of the rDNA) to uncover genomic diversity in Glycine canescens and Glycine tomentella and to establish their phylogenetic relationships with the other diploid species of the genus Glycine. Cytogenetics revealed that G. canescens accessions (PIs 583944, 583946, 583953, and 591575) from Western Australia were genomically similar. However, they were differentiated by a paracentric inve

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Beserra, Poliana S., Gustavo A. Sales, Expedito J. M. Santana, et al. "Relação entre a biometria ultra-sonográfica em modo B do bulbo ocular e os diâmetros fronto occiptal e bizigomático em Canis familiaris." Pesquisa Veterinária Brasileira 29, no. 4 (2009): 286–90. http://dx.doi.org/10.1590/s0100-736x2009000400002.

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Avaliou-se 31 cães saudáveis, sem raça definida, sendo 10 machos e 21 fêmeas, com 8 meses a 7 anos de idade e peso de1,5-28 kg. Inicialmente foram mensurados os diâmetros fronto-occiptal (DFO) e bizigomático (DBZ) do crânio com o auxílio de um paquímetro. A ultra-sonografia transpalpebral em modo-B foi realizada para mensurar as estruturas do bulbo ocular, conforme se segue: D1- espessura da córnea; D2- distância entre o ponto central da imagem da córnea e a da cápsula anterior do cristalino (câmara anterior); D3- distância entre o ponto central da imagem da córnea e a da cápsula posterior do

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Niu, Jin, Chun-Hou Li, Yong-Jian Liu, et al. "Dietary values of astaxanthin and canthaxanthin in Penaeus monodon in the presence and absence of cholesterol supplementation: effect on growth, nutrient digestibility and tissue carotenoid composition." British Journal of Nutrition 108, no. 1 (2011): 80–91. http://dx.doi.org/10.1017/s0007114511005423.

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Penaeus monodon (mean initial wet weight 1·19 (se 0·01) g) were fed seven diets in triplicate: a control diet (D1) without carotenoids; three diets formulated to supply 0·1 % astaxanthin alone (D2), 0·2 % astaxanthin alone (D3), and a combination of 0·1 % astaxanthin and 1 % cholesterol (D4); three diets with 0·07 % canthaxanthin alone (D5), 0·13 % canthaxanthin alone (D6), and a combination of 0·07 % canthaxanthin and 1 % cholesterol (D7). Weight gain (WG, %), specific growth rate (SGR, %/d) and survival were chosen as parameters of shrimp growth performance. Total antioxidant status (TAS), s

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Banobe, Christin Octavia, I. Gusti Ayu Wita Kusumawati, and Ni Ketut Wiradnyani. "NILAI ZAT GIZI MAKRO DAN AKTIVITAS ANTIOKSIDAN TEMPE KEDELAI (Glycine max L.) KOMBINASI BIJI KECIPIR (Psophocarpus tetragonolobus L.)." Pro Food 5, no. 2 (2019): 486. http://dx.doi.org/10.29303/profood.v5i2.111.

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ABSTRAK  Dangerous diseases, such as cancer, cardiovascular disease and degenerative diseases including diabetes are the roles of oxidative stress caused by free radicals. Antioxidants are needed by the body to overcome and prevent oxidative stress. Soybean (Glycine max L.) has been studied in recent years as an antioxidant. In addition to soybeans, winged bean is also a plant that has the same activity as soybeans.The purpose of this study was to determine the value of macro nutrients and antioxidant activity of soybean tempeh products with a combination of winged beans. The soybean wit

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Zeng, Chunyu, Meng Zhang, Laureano D. Asico, Gilbert M. Eisner, and Pedro A. Jose. "The dopaminergic system in hypertension." Clinical Science 112, no. 12 (2007): 583–97. http://dx.doi.org/10.1042/cs20070018.

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Dopamine plays an important role in the pathogenesis of hypertension by regulating epithelial sodium transport, vascular smooth muscle contractility and production of reactive oxygen species and by interacting with the renin–angiotensin and sympathetic nervous systems. Dopamine receptors are classified into D1-like (D1 and D5) and D2-like (D2, D3 and D4) subtypes based on their structure and pharmacology. Each of the dopamine receptor subtypes participates in the regulation of blood pressure by mechanisms specific for the subtype. Some receptors regulate blood pressure by influencing the centr

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Zeng, Chunyu, Ines Armando, Yingjin Luo, Gilbert M. Eisner, Robin A. Felder, and Pedro A. Jose. "Dysregulation of dopamine-dependent mechanisms as a determinant of hypertension: studies in dopamine receptor knockout mice." American Journal of Physiology-Heart and Circulatory Physiology 294, no. 2 (2008): H551—H569. http://dx.doi.org/10.1152/ajpheart.01036.2007.

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Dopamine plays an important role in the pathogenesis of hypertension by regulating epithelial sodium transport and by interacting with vasoactive hormones/humoral factors, such as aldosterone, angiotensin, catecholamines, endothelin, oxytocin, prolactin pro-opiomelancortin, reactive oxygen species, renin, and vasopressin. Dopamine receptors are classified into D1-like (D1 and D5) and D2-like (D2, D3, and D4) subtypes based on their structure and pharmacology. In recent years, mice deficient in one or more of the five dopamine receptor subtypes have been generated, leading to a better understan

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Jose, P. A., J. R. Raymond, M. D. Bates, A. Aperia, R. A. Felder, and R. M. Carey. "The renal dopamine receptors." Journal of the American Society of Nephrology 2, no. 8 (1992): 1265–78. http://dx.doi.org/10.1681/asn.v281265.

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Dopamine is an endogenous catecholamine that modulates many functions including behavior, movement, nerve conduction, hormone synthesis and release, blood pressure, and ion fluxes. Dopamine receptors in the brain have been classically divided into D1 and D2 subtypes, based on pharmacological data. However, molecular biology techniques have identified many more dopamine receptor subtypes. Several of the receptors cloned from the brain correspond to the classically described D1 and D2 receptors. Several D1 receptor subtypes have been cloned (D1A, D1B, and D5) and are each coupled to the stimulat

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Muir, T. L. "Structural evolution of the Hemlo greenstone belt in the vicinity of the world-class Hemlo gold deposit." Canadian Journal of Earth Sciences 40, no. 3 (2003): 395–430. http://dx.doi.org/10.1139/e03-004.

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A complex history of volcano-sedimentary deposition, polyphase strain, multiple intrusive events, and various stages of porphyroblastesis is indicated for the Hemlo gold deposit area within the Hemlo greenstone belt. Structural elements can be assigned to at least six stages of development (D1D6). D1 generated small-scale folds and low-angle faults (thrusts?) with no planar fabric, except within strain aureoles around the earliest intrusions. D2 was a progressive event resulting from northeast-directed compression, which generated regional, predominantly S-shaped folds (early D2); penetrative

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Prabhu, Varun V., Neel S. Madhukar, Coryandar Gilvary, et al. "Dopamine Receptor D5 is a Modulator of Tumor Response to Dopamine Receptor D2 Antagonism." Clinical Cancer Research 25, no. 7 (2018): 2305–13. http://dx.doi.org/10.1158/1078-0432.ccr-18-2572.

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