Relevant bibliographies by topics / DAA

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  2. Dissertations / Theses
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  5. Conference papers
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Academic literature on the topic 'DAA'

Author: Grafiati
Published: 4 June 2021
Last updated: 18 June 2025

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Journal articles on the topic "DAA"

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GEERS, THOMAS L., and BRADY J. TOOTHAKER. "THIRD-ORDER DOUBLY ASYMPTOTIC APPROXIMATIONS FOR COMPUTATIONAL ACOUSTICS." Journal of Computational Acoustics 08, no. 01 (2000): 101–20. http://dx.doi.org/10.1142/s0218396x00000078.

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A fully and symmetrically matched, third-order doubly asymptotic computational boundary (DAA3) is presented in both operator and matrix forms. Its performance is then compared with that of other DAA boundaries for the spherical geometry, which admits an exact series solution. Based on stability, accuracy and passivity as performance criteria, DAA3 is found to be superior to all other DAAs formulated to date. However, there are other third-order forms that are nearly as good, and are easier to implement in boundary-element form. The existence of both DAA2 and DAA3 boundaries enables the analyst to assess solution accuracy for a given problem through the comparison of results produced with these higher approximations of different order.
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Yoder, Laura E., John G. Rehm, Hunter R. Smith, et al. "Evaluation of Simulated Shelf-Life Conditions for Food Service Applications on Chicken Tenderloins." Animals 11, no. 7 (2021): 2028. http://dx.doi.org/10.3390/ani11072028.

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The objective of this study was to validate the shelf-life of marinated and frozen chicken tenderloins. Treatments were randomly assigned to the age of the tenderloins post-harvest, days aged (DA): DA4, DA5, DA6, DA7, and DA8. Microbial analyses were used to analyze the growth of aerobic, psychotropic, and lactobacilli bacteria to assess the shelf-life of bulk-packaged chicken tenderloins. Tenderloins were sampled fresh, then vacuum tumbled in a marinade. After marination, the tenderloins were sampled with the remaining tenderloins packaged and frozen (−25 °C). After freezing the chicken tenderloins were slacked in a refrigerated cooler (2.2 °C) for up to 132 h (h) and sampled at 36 h, then every 24 h following. After marination, each treatment significantly (p < 0.05) decreased in aerobic and psychotropic counts except DA4. During slacking, no treatment crossed the threshold of 106 CFU/mL (Log 6) set for this study. Though none crossed the threshold, treatments DA4, DA5, and DA6 had significant (p < 0.05) increases in aerobic bacteria after 7 days of age. The psychotropic bacteria continuously grew at each sampling period, with DA4 and DA5 surpassing the other treatments (p < 0.05) at 108 h and 132 h reaching 105 CFU/mL. Every treatment remained below the spoilage threshold, suggesting that this method of storage is suitable for chicken tenderloin shelf-life.
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Sahoo, Monalisha, Laxmipriya Sahoo, Anuj Kumar Rai, et al. "Assessment of Physiological Maturity through Pod and Seed Developmental Pattern in Local Land Races of Green Gram (Vigna radiata L. Wilczek)." International Journal of Plant & Soil Science 37, no. 3 (2025): 71–79. https://doi.org/10.9734/ijpss/2025/v37i35348.

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For assessing physiological maturity through pod and seed developmental patterns in local landraces of green gram (Vigna radiata L. Wilczek), a sufficient number of flowers were tagged on the day of anthesis for all the genotypes. Ten fruits were harvested per replication for each genotype of five harvesting stages starting from 7 days after anthesis and at seven-day intervals. The harvested pods and seeds were utilized for the study. Enhancement in pod length, weight, no of seed/pod and 1000 seed weight was noted up to 28 DAA in most of the genotypes. Continuous increase in seed fresh weight was noted up to 28 DAA whereas dry weight continued to increase till 35 DAA in correspondence with loss in moisture. Maximum dry matter accumulation was between 14 DAA-21 DAA. Significant moisture loss was recorded for all genotypes from 21 DAA-35 DAA. The highest germination was achieved at 35 DAA for all genotypes except V1 and V4 for which the highest germination was recorded at 28 DAA. Enhancement in shoot length was up to 35 DAA for all genotypes whereas for root length it was till 28 DAA for most of the genotypes. Vigour Index 1 was noted to be constantly enhanced with progress in development up to 35 DAA for most of the genotypes whereas an increase in vigour index II was 28 DAA except V5. Germination and vigor index decreased after 28 DAA in 2 genotypes and 35 DAA for 3 genotypes indicating attainment of physiological maturity between 28-35 DAA.
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Pietrzak, J. R. T., D. B. Geldenhuys, N. Sikhauli, J. N. Cakic, and L. Mokete. "Current perspectives of south african orthopaedic surgeons to the direct anterior approach in total hip arthroplasty." East African Orthopaedic Journal 18, no. 1 (2024): 21–33. http://dx.doi.org/10.4314/eaoj.v18i1.4.

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Background: Despite the global increase in popularity for the use of the Direct Anterior Approach (DAA) for Total Hip Arthroplasty (THA), the current beliefs and reasons for its use and disuse amongst South African orthopaedic surgeons is not well understood. Objective: To determine the perspectives regarding DAA compared to other surgical approaches to THA. Methods: We conducted an anonymous online survey sent to all current members of the South African Orthopedic Association (SAOA). Results: The response rate was 24.25% (n=194). There were 76 (39.18%) respondents that have performed DAA (DAA Performers) and 118 (60.82%) that have never performed DAA (DAA nonperformers). A proportion of 50% and 11.84% of DAA performers were between 30 to 45 years and older than 60 years of age, respectively (p<0.000). The DAA is the preferred approach to THA for 36.84% (n=28) of DAA performers, whilst 63.16% (n=48) prefer an alternative approach. Both DAA performers who prefer DAA and those who prefer alternative approaches consider DAA more satisfactory for length of hospital stay (p<0.000) and short-term functional outcomes (p=0.002) compared to other surgical approaches. For DAA non-performers, the primary reasons for not performing DAA THA were inexperience in surgical technique (72.09%), increased operative time (12.79%), unsatisfactory outcomes (27.91%) and learning curve (67.44%). There were 5 (18.52%) and 30 (70.33%) surgeons who have been in clinical practice for more than 10 years that do and do not intend to use DAA in the future, respectively (p<0.000). Conclusion: The trends of the adoption of the DAA by South African orthopaedic surgeons show increasing popularity, similar to patterns seen in the United Kingdom and the United States of America. Younger surgeons are more likely to perform the DAA THA whilst more experienced surgeons are less likely to deviate from their current standard of practice.
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Iranpour, Nima, Gregory J. Dore, Marianne Martinello, Gail V. Matthews, Jason Grebely, and Behzad Hajarizadeh. "Estimated uptake of hepatitis C direct-acting antiviral treatment among individuals with HIV co-infection in Australia: a retrospective cohort study." Sexual Health 17, no. 3 (2020): 223. http://dx.doi.org/10.1071/sh19101.

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Background Unrestricted access to direct-acting antiviral (DAA) therapy for hepatitis C virus (HCV) infection has been available in Australia since March 2016. Individuals with HIV–HCV co-infection are at a greater risk of liver fibrosis progression. This study estimated DAA treatment uptake among individuals with HIV–HCV co-infection, during the first year of DAA treatment access in Australia. Methods: Pharmaceutical Benefits Scheme (PBS) data on dispensed DAA and antiretroviral therapy (ART) prescriptions from March 2016 to March 2017 were used for analysis. Results: During March 2016 to March 2017, a total of 935 individuals with HIV–HCV co-infection were receiving ART and initiated DAA treatment, with 93% to 97% completing their prescribed course. Estimated DAA treatment uptake in the HIV–HCV-infected population was 41% (935/2290). Most were men (94%). Median age was 50 years. DAA treatment was initiated by specialists in 64% of cases (n = 602), and by general practitioners (GPs) in 25% of cases (n = 238). The proportion of individuals initiated on DAA by GPs increased from 20% in March–April 2016 to 26% in January–March 2017. Most specialists (77%) and GPs (72%) initiated DAA treatment for one to three patients. Among individuals initiated on DAA by GPs, 68% received their ART prescription from the same GP. Conclusions: A high level of DAA treatment uptake and completion was observed among individuals with HIV–HCV co-infection during the first year of DAA treatment access. The proportion of individuals prescribed DAA by GPs increased over time; this is important for broadened access.
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Gao, Zhan, Zhihao Yu, Xiaoli Zhang, et al. "Exploration on Optimized Control Way of D-Amino Acid for Efficiently Mitigating Membrane Biofouling of Membrane Bioreactor." Membranes 11, no. 8 (2021): 612. http://dx.doi.org/10.3390/membranes11080612.

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The thorny issue of membrane biofouling in membrane bioreactors (MBR) calls for new effective control measures. Herein, D-amino acid (DAA) was employed to mediate MBR membrane biofouling by inhibiting biofilm information and disintegrating formed biofilm. Different DAA control ways involving membrane property, DAA-adding timing, and DAA-control mode were explored through experiments and the multiple linear regression model and the response surface methodology. The optimized DAA control ways were acquired, involving DAA used as an active agent, and the DAA-adding timing of 4 h cultured before running, as well as both hydrophilic and hydrophobic membrane, resulting in an approximately 40.24% decrease in the membrane biofouling rate in comparison with the conventional MBR. DAA is an efficient membrane biofouling mediating approach for MBR under optimized control ways combination and a facile solution for solving membrane biofouling in actual membrane systems.
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Feng, Huang, Xiaohui Bian, Yuru Lan, Yunfei Ling, and Yong jun Qian. "Tetralogy of Fallot with Double Aortic Arch in an 8-Month-Old Girl: A Rare Association." Heart Surgery Forum 23, no. 4 (2020): E507—E509. http://dx.doi.org/10.1532/hsf.2945.

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Double aortic arch (DAA) is an extremely rare congenital anomaly that can be divided into right dominant, left dominant, and balanced DAA according to the relative size of the two arches. The incidence of balanced DAA is only 5% among double arch anomalies. DAA is symptomatic only when it produces symptoms secondary to compression of the trachea or esophagus. DAA is rarely associated with other congenital heart diseases. In this report, we present a rare case of asymptomatic DAA combined with Tetralogy of Fallot (TOF) in an 8-month-old girl.
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Kim, Won-Jin, Woong Kim, Jang-Mi Bae, Jungsoo Gim, and Seok-Jun Kim. "Dehydroabietic Acid Is a Novel Survivin Inhibitor for Gastric Cancer." Plants 10, no. 6 (2021): 1047. http://dx.doi.org/10.3390/plants10061047.

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Gastric cancer is a malignant tumor with a high incidence and mortality rate worldwide. Nevertheless, anticancer drugs that can be used for gastric cancer treatment are limited. Therefore, it is important to develop targeted anticancer drugs for the treatment of gastric cancer. Dehydroabietic acid (DAA) is a diterpene found in tree pine. Previous studies have demonstrated that DAA inhibits gastric cancer cell proliferation by inducing apoptosis. However, we did not know how DAA inhibits the proliferation of gastric cancer cells through apoptosis. In this study, we attempted to identify the genes that induce cell cycle arrest and cell death, as well as those which are altered by DAA treatment. DAA-regulated genes were screened using RNA-Seq and differentially expressed genes (DEGs) analysis in AGS cells. RNA-Seq analysis revealed that the expression of survivin, an apoptosis inhibitor, was significantly reduced by DAA treatment. We also confirmed that DAA decreased survivin expression by RT-PCR and Western blotting analysis. In addition, the ability of DAA to inhibit survivin was compared to that of YM-155, a known survivin inhibitor. DAA was found to have a stronger inhibitory effect in comparison with YM-155. DAA also caused an increase in cleaved caspase-3, an apoptosis-activating protein. In conclusion, DAA is a potential anticancer agent for gastric cancer that inhibits survivin expression.
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Wangensteen, Rosemary, Manuel Gómez-Guzmán, Inmaculada Banegas, et al. "Vasoconstrictor and Pressor Effects of Des-Aspartate-Angiotensin I in Rat." Biomedicines 10, no. 6 (2022): 1230. http://dx.doi.org/10.3390/biomedicines10061230.

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This study investigated the vasoactive effects of des-aspartate-angiotensin-I (DAA-I) in male Wistar rats on whole body vascular bed, isolated perfused kidneys, and aortic rings. Dose–response curves to DAA-I were compared with those to angiotensin II (Ang II). The Ang II-type-1 (AT1) receptor blocker, losartan, was used to evaluate the role of AT1 receptors in the responses to DAA-I. Studies were also conducted of the responsiveness in aortic rings after endothelium removal, nitric oxide synthase inhibition, or AT2 receptor blockade. DAA-I induced a dose-related systemic pressor response that was shifted to the right compared with Ang II. Losartan markedly attenuated the responsiveness to DAA-I. DAA-I showed a similar pattern in renal vasculature and aortic rings. In aortic rings, removal of endothelium and nitric oxide inhibition increased the sensitivity and maximal response to DAA-I and Ang II. AT2 receptor blockade did not significantly affect the responsiveness to DAA-I. According to these findings, DAA-I increases the systemic blood pressure and vascular tone in conductance and resistance vessels via AT1 receptor activation. This vasoconstrictor effect of DAA-I participates in the homeostatic control of arterial pressure, which can also contribute to the pathogenesis of hypertension. DAA-I may therefore be a potential therapeutic target in cardiovascular disease.
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Lin, Shu-Hsien, Kun-Ta Wu, Chih-Chi Wang, et al. "Immune Responses to Anti-Hepatitis C Virus Antibodies during Pre-Liver Transplantation Direct-Acting Antiviral Therapy in Hepatitis C Virus-Infected Recipients Associated with Post-Liver Transplantation Allograft Injury." Antibodies 13, no. 1 (2024): 7. http://dx.doi.org/10.3390/antib13010007.

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Background and Aims: The impact of antibody responses following direct-acting antiviral (DAA) therapy in hepatitis C virus (HCV)-infected recipients before and after liver transplantation (LT) is still undetermined. Methods: In this observational cohort study, we aimed to explore the association between changes in anti-HCV antibody titers following pre-LT DAA therapy and allograft injury, including biliary complications (BCs) and acute cellular rejection (ACR). Results: A total of 153 cases were enrolled from January 2015 to February 2021. Serum anti-HCV antibody titers were assessed before and after (day 30) LT. Among all recipients, 31/153 (20.3%) had pre-LT DAA therapy (the DAA group) and 122/153 (79.7%) did not undergo pre-LT DAA therapy (the DAA-naïve group). A higher incidence of post-LT BCs was observed in the DAA group (p = 0.028). Compared with the DAA-naïve group, the DAA group had a significantly higher mean level of anti-HCV titer upregulation (p = 0.0024); furthermore, among the recipients with BCs (n = 28) and ACR (n = 41), those in the DAA group exhibited significantly higher mean levels of anti-HCV antibody titer upregulation (p < 0.005). Conclusions: In conclusion, we speculate that the upregulation of anti-HCV antibody titers, which might have been induced via the restoration of HCV-specific immune responses through pre-LT DAA therapy, was associated with post-LT allograft injury.
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Dissertations / Theses on the topic "DAA"

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Baskin, Cyndy. ""Mino-Yaa-Daa: An urban community-based approach"." School of Native Human Services, 1997. http://142.51.24.159/dspace/handle/10219/471.

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Gabriel Dumont Non-Profit Homes (Metro Toronto) Inc. includes a centralized 80 unit apartment complex and 7 townhouses on a separate site. Located in Scarborough, Ontario all units have 3 or 4 bedrooms. Incorporated in 1985 and opened in 1986, the complex is financially sponsored by the Canada Mortage and Housing Corporation. Geared to income housing is offered on a monthly rent-geared-to-income basis. The majority of families in the complex are headed by single mothers.
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Shetty, Siddharth. "Detect and Avoid (DAA) mechanism for coexistence of commercial WiMedia Ultrawideband products with WiMax service." Diss., Connect to online resource, 2006. http://gateway.proquest.com/openurl?url_ver=Z39.88-2004&rft_val_fmt=info:ofi/fmt:kev:mtx:dissertation&res_dat=xri:pqdiss&rft_dat=xri:pqdiss:1435229.

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Nordien, Rozeena. "A Decade of Hepatitis C at the UCT/GSH Liver Clinic in the Pre-DAA era." Master's thesis, Faculty of Health Sciences, 2019. http://hdl.handle.net/11427/31175.

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Background Hepatitis C (HCV) in South Africa is incompletely characterised and understood. Epidemiological and clinical data will better inform our understanding and assist national policy decision making. On the background of more than two decades of clinical challenges in HCV management, the advent of direct acting antivirals (DAA) now makes HCV elimination plausible. To better understand the base from which we come, we elected to review and characterise our HCV experience at Groote Schuur Hospital (GSH) in the Pegylated interferon (Peg-IFN) and Ribavirin (RBV) management era. Methods Patients with chronic HCV attending GSH Liver Clinic from 2002 to 2014, were included, in the analysis. Relevant data were extracted from a registry and existing clinical records accessed. Two brands of Peg-IFN were available and those treated with the first generation add-on protease inhibitor, telaprevir, were included. Results 238 patients were included in the analysis, median age of 47 (IQR 37-58) years, men 60.5%. Men were significantly younger than women, 43.5 (35-52) vs 55 (42-64) years, respectively, p< 0.0001. Ethnically, the majority were white (55.9%) or mixed-ancestry (21.8%), 16.4% were HIV co-infected, 3.7% hepatitis B (HBV) co-infected and 0.4% triple infected with HCV, HBV and HIV. The most likely mode of HCV acquisition was blood/blood product exposure prior to 1992 (32.8%) and injecting drug use (IDU) 17.6%, while 30.3%, had no clear risk factor identifiable. Genotypes (GT) 1 to 5 were observed with GT-1 (34.9%) predominating. In those biopsied, (n=90), 30% ≥F3 fibrosis, with 15.6% cirrhotic. With IL28B polymorphisms, heterozygous CT (23.9%) and CC genotype (15.5%), were most frequent. 32.6% accessed Peg-IFN/Ribavirin-based therapy, 6.5% (n=5) with add-on telaprevir. GT-1 (35.1%) was most prevalent in the treatment group, followed by GT-3 (26%) and GT-5 (18.2%); 10% were HIV co-infected. Overall SVR rate was 75.3% with 37% of GT-1 not achieving SVR; 49.4% experienced adverse events including cytopaenias (32.5%) and depression (15.6%) with 15.6% requiring erythropoietin for anaemia and 15.6% GM-CSF for neutropaenia. Conclusion HCV patients in the Peg-IFN/Ribavirin management era typified the epidemiology of HCV. GT distribution was pangenotypic and treatment outcomes were encouraging despite treatment challenges. Patient selection, IL28B and sensible cytopaenia support, likely accounted for this. However numbers treated were limited and the DAA era of therapy allows for a rapid expansion of therapy with now growing numbers of patients and a changing local epidemiology.
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Jayaraman, Jayakumar. "Dental age assessment (DAA) : development and validation of reference dataset for southern Chinese and its application to East Asian populations." Thesis, The University of Hong Kong (Pokfulam, Hong Kong), 2014. http://hdl.handle.net/10722/207191.

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Age assessment which is an integral part of forensic and clinical practice when assessed using the extent of dental development has proven to be more accurate than other methods. Variations in dental development have necessitated the construction of ethnic specific reference datasets (RDS) to ensure accurate age assessments. Age estimated from ethnically different RDS in southern Chinese subjects has been shown to be inaccurate. A systematic review and meta-analysis from the most commonly used French-Canadian dataset revealed consistent over-estimations of age of global population groups, inferring the need for population specific RDS. A study which compared a group of 400 five years old children born in the 1980s and the 2000s demonstrated that children born in recent decades have more advanced dental development. Hence, only the most recent samples were included in the construction of a RDS for southern Chinese using dental panoramic radiographs of 2306 subjects. The reference dataset was subsequently validated on 484 subjects of southern Chinese origin by conducting dental age assessments (DAA) using un-weighted and weighted methods of dental age calculations. Paired t-test demonstrated that all methods of assessments were able to accurately estimate the age (p>0.05). The overall age differences ranged from -0.01 to 0.11 years for males and -0.03 to 0.10 years for females respectively. In addition, to test the accuracy of different ethnic datasets, 266 southern Chinese subjects for whom age had been estimated using the UK Caucasian and French-Canadian datasets were re-scored using the southern Chinese RDS. The latter was able to estimate the age of 80% of the subjects within a range of 12 months and the importance of population specific reference standards was elucidated. The validated southern Chinese RDS on dental development can thus be used to estimate the age of children and young adults of southern Chinese origin. This RDS was also tested for applicability on the records of 953 subject obtained from Japan, Thailand and Philippines. A similar method of validation was conducted and the southern Chinese RDS estimated the age of Thai males, Filipino and Japanese subjects with a reasonable degree of accuracy. The genetic similarity between the southern Han Chinese and the other East Asian population groups may account for the obtained accuracy. The secular trend study was the first of its kind study in Asia that demonstrated advanced dental maturation in children born in recent decades. Natural calamities that strike East Asia leave thousands of people missing. In those circumstances, dental age assessment using the southern Chinese RDS would help in the process of identifying deceased victims. Furthermore, only half of the children in the world below the age of five years are registered; thus the need for determining age is of foremost importance to safeguard them against age specific crimes. Methods of establishing reference datasets and conducting accurate age assessments that have been investigated and tested in this study indicate that the methodology can be applied to any ethnic population group in the world.<br>published_or_final_version<br>Paediatric Dentistry<br>Doctoral<br>Doctor of Philosophy
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Edraki, Julia, and Lehmann Cherryl Wabingga-. "Hundars betydelse för att främja hälsa hos personer med demenssjukdom : En litteraturöversikt." Thesis, Ersta Sköndal Bräcke högskola, Institutionen för vårdvetenskap, 2018. http://urn.kb.se/resolve?urn=urn:nbn:se:esh:diva-6819.

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Bakgrund: Demenssjukdomar är en av världens största folksjukdomar. Sjukdomen karakteriseras av nedsatt kognition, perceptionssvårigheter och personlighetsförändringar. Samtidigt kan demenssjukdomen medföra sekundära symtom såsom depression och aggression. Dessa symtom kan uppkomma till följd av att individen upplever hot för sin identitet som därmed påverkar individens hälsa negativt. Sedan många hundra år tillbaka i tiden har hundar ansetts ha en positiv effekt på människors hälsa. I samband med att den medicinska vetenskapen fokuserade mer på läkemedlens botande möjlighet hamnade djurens effekt i skuggan. Idag kan hundar användas som behandlingstillägg inom många olika områden och som olika behandlingsformer.  Syfte: Syftet med studien är att belysa hundens betydelse som resurs för att främja god hälsa hos personer med demenssjukdom. Metod: En litteraturöversikt har genomförts i detta examensarbete, där det analyserades 10 vårdvetenskapliga artiklar av kvantitativ forskningsdesign.  Resultat: Resultatet består av fyra kategorier: hundens påverkan på psykisk hälsa, hundens påverkan på beteende, hundens påverkan på kognition och hundens påverkan på fysisk funktion. Minskad depression, aggression, förbättrad social kompetens och kognition kunde påvisas av interventioner med hund. Det har dock inte framkommit att antidepressiva läkemedel reducerades i samband med interventionen. En studie har kunnat påvisa effekten av hundar på fysisk funktion hos personer med demenssjukdom.  Diskussion:Hundar har genom sin närvaro en positiv inverkan på hälsan hos personer med demenssjukdom genom att dämpa symtom som sjukdomen medför. Lite underlag kunde även hittas för att hundar kan positivt påverka den fysiska funktionen genom att uppmuntra personen med demenssjukdom till ökad aktivitet. Dessa djur kan vara den enkla och eleganta resursen som Barker förespråkar för att främja hälsa hos personer med demenssjukdom.
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Piovesan, Sara. "VIROLOGICAL AND CLINICAL OUTCOMES WITH ORAL ANTIVIRAL THERAPY IN HCV-RELATED CIRRHOSIS." Doctoral thesis, Università degli studi di Padova, 2017. http://hdl.handle.net/11577/3423263.

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The hepatitis C virus (HCV) treatment landscape has rapidly changed over recent years. The development of direct-acting antiviral (DAA) agents that specifically target various steps in the HCV lifecycle has revolutionized therapeutic options for patients with HCV, with the development of highly effective and well-tolerated oral interferon-free (IFN-free) regimens. There are several DAAs that have been approved and others that are currently in development, targeting different nonstructural HCV or host proteins that are essential for HCV replication. Data on virological response in different HCV genotypes and patients subgroups are well established in the literature, while results on clinical outcome are much more limited. In this thesis, I will describe real-life virological and clinical outcome with DAA therapy in a large cohort of patients with HCV treated in clinical practice in the Veneto Region. For this purpose, we have used the NAVIGATORE web-platform that is recording and monitoring all HCV-DAA based treatments in the Veneto region and we have assessed virological and clinical outcomes of DAAs treatment in 3 subgroups of patients: 1) HCV infected cirrhotics (both compensated and decompensated) to clarify drugs efficacy and clinical outcomes, including long term benefits of treatment, 2) Patients with extrahepatic manifestations due to HCV and 3) patients with HCV aged > 70 years. Our analysis has been based on a cohort of 2946 cirrhotic patients. DAAs were safe and efficacious in these patients, including those with advanced, or decompensated cirrhosis. SVR rates for most genotypes were excellent, but the initially used Sofosbuvir plus Ribavirin regimens were suboptimal in HCV-1 and HCV-3 infected patients. Efficacy was not significantly affected by common comorbidities but it was reduced in patients with Child B cirrhosis. Severe adverse event were unusually: tolerability and safety were excellent in patients with Child A cirrhosis, while were reduced in Child B patients, particularly when treated with Ribavirin containing regimens. Patients with decompensated cirrhosis often showed an improvement in Child scores and patients with compensated cirrhosis showed a reduced incidence of complications, compared to the expected rates in the natural history of untreated disease. The "de novo" incidence of HCC was also reduced during and after DAA and the incidence of HCC recurrence not increased during and after DAAs. A subgroup of patients developed an aggressive type of HCC during therapy, and this was more frequent in non-responders, an observation that certainly deserves further evaluation. Extrahepatic manifestations of HCV infection also improved with successful antiviral therapy. Moreover, a sub-analysis in a group of patients over 70 years, the "elderly group", confirmed excellent safety and efficacy of DAAs also in this setting.<br>Il panorama del trattamento dell'epatite C si è rapidamente modificato negli ultimi 7 anni. Lo sviluppo di antivirali diretti (direct-acting antiviral = DAA), che hanno come bersaglio diversi punti nel ciclo vitale del virus dell'epatite C (HCV), ha rivoluzionato le opzioni terapeutiche per i pazienti con epatite C, con la disponibilità di regimi orali (non più basati sull'interferone) altamente efficaci e ottimamente tollerati. Ci sono diversi DAAs attualmente in sviluppo o già approvati, che hanno come bersaglio diverse proteine di HCV non-strutturali o altri targets essenziali per la replicazione di HCV. I dati di risposta virologica nei diversi genotipi HCV e in diversi sottogruppi di pazienti sono ben documentati in letteratura, mentre i risultati sugli outcomes clinici sono molto più limitati. In questa tesi sono descritti gli outcomes "real-life" clinici e virologici, ottenuti con la terapia con DAA in una larga coorte di pazienti con epatopatia HCV correlata, trattati nella pratica clinica nella Regione Veneto. A tal proposito, abbiamo usato la piattaforma NAVIGATORE, che registra e monitorizza tutti i trattamenti per HCV DAA-based in Veneto, ed abbiamo valutato gli outcomes clinici e virologici ottenuti con trattamenti con DAA in 3 gruppi di pazienti: 1) pazienti con cirrosi HCV correlata (sia compensati che scompensati) allo scopo di verificare l'efficacia e gli outcomes clinici, inclusi i benefici a lungo termine del trattamento, in questa categoria di pazienti., 2) pazienti con manifestazioni extraepatiche da HCV e 3) un gruppo di pazienti con età > 70 anni. La nostra analisi ha considerato una coorte di 2946 pazienti cirrotici. I DAAs si sono dimostrati sicuri ed efficaci in questi pazienti, inclusi quelli con cirrosi avanzata o scompensata. I tassi di SVR per la maggior parte dei genotipi sono stati eccellenti, ma i regimi usati inizialmente con solo sofosbuvir e ribavirina erano subottimali nei pazienti con infezione da genotipo 1 e 3. L'efficacia non è stata significativamente influenzata dalla presenza delle più comuni comorbidità, ma è risultata ridotta nei pazienti con cirrosi in Child B. Gli effetti collaterali gravi sono rari: la tollerabilità e la sicurezza sono state eccellenti nei pazienti sia con fibrosi F3 che in quelli con cirrosi in Child A, mentre sono risultate ridotte nei pazienti in Child B, particolarmente quando trattati con regimi contenenti ribavirina. I pazienti con cirrosi scompensata hanno spesso presentato un miglioramento nel punteggio di Child ed i pazienti con cirrosi compensata hanno mostrato una ridotta incidenza di complicanze rispetto ai tassi attesi nella storia naturale della malattia non trattata. L'incidenza di HCC "de novo" è risultata ridotta durante e dopo terapia con DAA e l'incidenza della recidiva di HCC non è aumentata durante o dopo terapia con DAA. Un sottogruppo di questi pazienti ha sviluppato un tipo di HCC più aggressivo durante la terapia, e ciò si è verificato più frequentemente nei pazienti non-responder alla terapia, osservazione questa che certo merita ulteriori valutazioni. Anche le manifestazioni extraepatiche HCV correlate sono migliorate in relazione al successo terapeutico. Inoltre una sub-analisi in un gruppo di pazienti ultra-settantenni ("gruppo Anziani") ha confermato una sicurezza ed una efficacia della terapia con DAA eccellenti anche in questo setting.
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Renken, Svenja [Verfasser]. "Vergleich der Implantation eines Hüftgelenkschaftes mit Bipolarkopf nach Schenkelhalsfraktur in konventioneller Technik nach Watson-Jones versus minimal invasiv direkt vorderem Zugang (DAA) in Bezug auf die Frühmobilisationsphase : eine prospektiv randomisierte Studie / Svenja Renken." Lübeck : Zentrale Hochschulbibliothek Lübeck, 2012. http://d-nb.info/1028952201/34.

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Yuen, Hong-chau. "Zhong Lü nei dan Dao De guan yan jiu /." View abstract or full-text, 2004. http://library.ust.hk/cgi/db/thesis.pl?HUMA%202004%20YUEN.

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Li, Pei. "Sui Tang wu dai dao jiao mei xue si xiang yan jiu." Chengdu Shi : Sichuan chu ban ji tuan Ba Shu shu she, 2005.

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Luk, Kei Yeung. "Lao Zhuang "dao" yu "wu wei" gai nian de dang dai quan shi /." View abstract or full-text, 2009. http://library.ust.hk/cgi/db/thesis.pl?HUMA%202009%20LUK.

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Books on the topic "DAA"

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Saggu, Balwant Singh. Harmeet daa ghar. B.S. Saggu, 1986.

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Khudri, Amin. Dawa li kull daa. Maktabat Madbūlī, 2003.

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Atwal, Harjeet. Sappan daa bhar bartania. Shiv Prakashan, 2004.

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Rana, Ranjit singh. Saadey Samean Daa Punjab. Panj Nad publicatuins, 2000.

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T͡Sydenov, Kim. Busakhal daa khabar: Zokhëolnuudaĭ nom. Buri︠a︡ad-Mongol Nom Khėblėl, 2017.

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UNICEF, ed. Daa ta yeeri daabaaru Yini. Programme Education UNICEF, 1994.

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B, Gonchikova R., T͡S︡ybenova N. T, and Gėndėnova T͡S︡ M, eds. Buri͡a︡adkhan ai͡a︡lgam ḣaĭkhan daa--: Duunuud. Buri͡a︡adaĭ nomoĭ khėblėl, 1985.

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Baast, B. Khaana amʹdarna daa, khȯȯrkhiĭ!: (tuuzh, zhu̇zhig, tėmdėglėl, zakhidal). Mȯnkhiĭn U̇sėg, 2013.

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Matius, Kanangadju, ed. Tesa-tesa eo-eo ri ara basa Daa =: Percakapan sehari-hari dalam bahasa Da'a = Everyday conversations in Da'a. Universitas Hasanuddin, 1989.

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Gwaai, Edenshaw, and Edenshaw Jaalen, eds. Daa _Galang sding: _Xaayda_Ga Giiahl_Galang ga = The two brothers : a Haida story = Les deux frères : un récit haïda. Summerthought Pub., 2011.

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Book chapters on the topic "DAA"

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Nakamura, Junichi. "Direct Anterior Approach (DAA)." In Advances in Total Hip Arthroplasty. Springer Nature Singapore, 2024. http://dx.doi.org/10.1007/978-981-97-2461-1_50.

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Zvi, Yoav S., and Chris Sambaziotis. "Direct Anterior Approach (DAA)." In Revision Total Hip Arthroplasty. Springer Nature Switzerland, 2025. https://doi.org/10.1007/978-3-031-83959-7_19.

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Yang, Bo, Kang Yang, Yu Qin, Zhenfeng Zhang, and Dengguo Feng. "DAA-TZ: An Efficient DAA Scheme for Mobile Devices Using ARM TrustZone." In Trust and Trustworthy Computing. Springer International Publishing, 2015. http://dx.doi.org/10.1007/978-3-319-22846-4_13.

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Qin, Yu, Xiaobo Chu, Dengguo Feng, and Wei Feng. "DAA Protocol Analysis and Verification." In Trusted Systems. Springer Berlin Heidelberg, 2012. http://dx.doi.org/10.1007/978-3-642-32298-3_21.

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Cesena, Emanuele, Hans Löhr, Gianluca Ramunno, Ahmad-Reza Sadeghi, and Davide Vernizzi. "Anonymous Authentication with TLS and DAA." In Trust and Trustworthy Computing. Springer Berlin Heidelberg, 2010. http://dx.doi.org/10.1007/978-3-642-13869-0_4.

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Chen, Liqun, Paul Morrissey, and Nigel P. Smart. "On Proofs of Security for DAA Schemes." In Provable Security. Springer Berlin Heidelberg, 2008. http://dx.doi.org/10.1007/978-3-540-88733-1_11.

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Xi, Li, Kang Yang, Zhenfeng Zhang, and Dengguo Feng. "DAA-Related APIs in TPM 2.0 Revisited." In Trust and Trustworthy Computing. Springer International Publishing, 2014. http://dx.doi.org/10.1007/978-3-319-08593-7_1.

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Proudler, Graeme, Liqun Chen, and Chris Dalton. "Direct Anonymous Attestation (DAA) in More Depth." In Trusted Computing Platforms. Springer International Publishing, 2014. http://dx.doi.org/10.1007/978-3-319-08744-3_12.

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Chen, Liqun, and Rainer Urian. "DAA-A: Direct Anonymous Attestation with Attributes." In Trust and Trustworthy Computing. Springer International Publishing, 2015. http://dx.doi.org/10.1007/978-3-319-22846-4_14.

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Chen, Liqun. "A DAA Scheme Requiring Less TPM Resources." In Information Security and Cryptology. Springer Berlin Heidelberg, 2010. http://dx.doi.org/10.1007/978-3-642-16342-5_26.

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Conference papers on the topic "DAA"

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Qian, Jin, Jun Luo, Liquan Chen, Bangwei Yin, Jiaorui Shen, and Chao Chen. "A Lattice-Based Single-Domain DAA Protocol for Smart Grid Scenarios." In 2024 10th International Conference on Computer and Communications (ICCC). IEEE, 2024. https://doi.org/10.1109/iccc62609.2024.10942166.

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Stroeve, Sybert. "Stochastic Dynamic Agent-based Modelling for Evaluation of ACAS and DAA Systems." In 2025 Integrated Communications, Navigation and Surveillance Conference (ICNS). IEEE, 2025. https://doi.org/10.1109/icns65417.2025.10976787.

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Eckstein, Bruce. "UAS DAA architecture considerations." In 2015 Integrated Communication, Navigation and Surveillance Conference (ICNS). IEEE, 2015. http://dx.doi.org/10.1109/icnsurv.2015.7121364.

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Lin, C. E., P. C. Shao, H. T. Bui, and Y. Y. Lin. "DAA Solution on UTM." In 2021 Integrated Communications Navigation and Surveillance Conference (ICNS). IEEE, 2021. http://dx.doi.org/10.1109/icns52807.2021.9441641.

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Zhen, Hong-hu, and Yue Chen. "Bilinear Pairing Based DAA Protocol." In 2009 International Conference on Computational Intelligence and Natural Computing (CINC). IEEE, 2009. http://dx.doi.org/10.1109/cinc.2009.116.

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Sriraman, L., and T. N. Prabakar. "Multiplexer based two variables DAA." In 2014 2nd International Conference on Devices, Circuits and Systems (ICDCS). IEEE, 2014. http://dx.doi.org/10.1109/icdcsyst.2014.6926139.

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"RTCA SC-228 and DAA." In 2017 Integrated Communications, Navigation and Surveillance Conference (ICNS). IEEE, 2017. http://dx.doi.org/10.1109/icnsurv.2017.8012051.

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Euteneuer, Eric, Greg Loegering, Satish Krishnan, and Jim Jewell. "Required surveillance sensors for DAA." In 2014 IEEE/AIAA 33rd Digital Avionics Systems Conference (DASC). IEEE, 2014. http://dx.doi.org/10.1109/dasc.2014.6979508.

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Loegering, Greg. "Required surveillance sensors for DAA." In 2014 IEEE/AIAA 33rd Digital Avionics Systems Conference (DASC). IEEE, 2014. http://dx.doi.org/10.1109/dasc.2014.6979648.

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Dietz, J., C. Graf, P. Buggisch, et al. "Herkunft und Prävalenz von seltenen HCV Genotypen bei DAA-naiven und DAA-erfahrenen Patienten." In Viszeralmedizin 2021 Gemeinsame Jahrestagung Deutsche Gesellschaft für Gastroenterologie, Verdauungs- und Stoffwechselkrankheiten (DGVS), Sektion Endoskopie der DGVS, Deutsche Gesellschaft für Allgemein und Viszeralchirurgie (DGAV). Georg Thieme Verlag KG, 2021. http://dx.doi.org/10.1055/s-0041-1733694.

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Reports on the topic "DAA"

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Hung, Hsuan-Yu, and Chung-Yu Chen. The impact of Sofosbuvir/Velpatasvir/Voxilaprevir treatment on serum hyperglycemia in HCV infections: A Systematic Review. INPLASY - International Platform of Registered Systematic Review and Meta-analysis Protocols, 2021. http://dx.doi.org/10.37766/inplasy2021.12.0109.

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Review question / Objective: To assess the possible cause of events, the incidence of grade 3 hyperglycemia after treating Sofosbuvir/Velpatasvir/Voxilaprevir in HCV infections. Condition being studied: Sofosbuvir, velpatasvir, and voxilaprevir (SOF/VEL/VOX) is an effective, safe rescue therapy regimen for patients have previously been treated failure. Initiating Direct-Acting Antiviral (DAA) treatment for HCV infection with diabetes have experienced hypoglycemia, it could improve insulin resistance due to clean HCV. However, some studies shown that SOF/VEL/VOX has Grade 3 hyperglycemia adverse events. This finding contradicts that other DAAs studies. Information sources: Conducting a comprehensive literature search on the pubmed, Cochrane, clinicalkey, Embase, and MEDLINE electronic databases.
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Gaylord, J., S. Ruppert, G. Abdulla, and D. Laney. DOE Data Day Report. Office of Scientific and Technical Information (OSTI), 2019. http://dx.doi.org/10.2172/1579608.

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Canavan, G. H. Analysis of DNA impact test data. Office of Scientific and Technical Information (OSTI), 1997. http://dx.doi.org/10.2172/560796.

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Nasution, Sri. Tata Kelola Data dan Perlindungan Data Pribadi melalui ASEAN Digital Masterplan 2025. Center for Indonesian Policy Studies, 2021. http://dx.doi.org/10.35497/353778.

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Cindy, Massita Ayu, and Vivid Amalia Khusna. Potensi Industri Data Center Berbasis Energi Terbarukan untuk mendukung Keamanan Nasional. Purnomo Yusgiantoro Center, 2024. https://doi.org/10.33116/pyc-br-9.

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Dengan penetrasi internet mencapai 79,5% dari populasi Indonesia, kebutuhan akan layanan data center semakin meningkat seiring dengan transformasi digital yang pesat di sektor pemerintahan, ekonomi, dan layanan publik. Industri data center menghadapi tantangan besar terkait konsumsi energi dan dampak lingkungan, yang menuntut transisi ke energi terbarukan, seperti tenaga surya, angin, air, dan panas bumi. Indonesia memiliki keunggulan kompetitif berupa sumber daya energi terbarukan yang melimpah, konektivitas global, dan kebijakan pemerintah yang mendukung. Namun, implementasi data center berbasis energi hijau membutuhkan upaya strategis, seperti penyederhanaan proses perizinan, penguatan infrastruktur energi terbarukan, penerapan kebijakan efisiensi energi, dan insentif bagi investor. Laporan ini mengkaji potensi pengembangan industri pusat data (data center) berbasis energi terbarukan di Indonesia, yang memainkan peran strategis dalam mendukung keamanan nasional melalui penyediaan infrastruktur digital yang andal, berkelanjutan, dan ramah lingkungan. Rekomendasi strategis dalam laporan ini mencakup penerapan teknologi hemat energi, pemanfaatan Renewable Energy Certificates (REC), dan pengembangan mekanisme power wheeling untuk mendukung operasional data center yang ramah lingkungan.
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Ploskey, Gene R., Christopher B. Cook, P. Scott Titzler, and Russell A. Moursund. Optimization of Hydroacoustic Deployments at John Day Dam. Office of Scientific and Technical Information (OSTI), 2002. http://dx.doi.org/10.2172/15002441.

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Reid, D. R. Company data management: a day in the life. Natural Resources Canada/ESS/Scientific and Technical Publishing Services, 1994. http://dx.doi.org/10.4095/193890.

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Phillips, Sara. Cheaper gene screening makes for DNA data dilemma. Monash University, 2023. http://dx.doi.org/10.54377/fa80-9689.

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Ruslan, Kadir, and Octavia Prasetyo. Perbaikan Data Perkebunan Indonesia: Kopi, Gula dan Kakao. Center for Indonesian Policy Studies, 2021. http://dx.doi.org/10.35497/349237.

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Kotz, Andrew J., and Kenneth J. Kelly. MOVES Activity Updates Using Fleet DNA Data: Interim Report. Office of Scientific and Technical Information (OSTI), 2019. http://dx.doi.org/10.2172/1491376.

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