Academic literature on the topic 'Dalton Twp'
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Journal articles on the topic "Dalton Twp"
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Greisch, Jean-François, Sem Tamara, Richard A. Scheltema, Howard W. R. Maxwell, Robert D. Fagerlund, Peter C. Fineran, Stephan Tetter, Donald Hilvert, and Albert J. R. Heck. "Expanding the mass range for UVPD-based native top-down mass spectrometry." Chemical Science 10, no. 30 (2019): 7163–71. http://dx.doi.org/10.1039/c9sc01857c.
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Vorobiova, Lolita. "American Experience of the Dalton Plan in the Dutch Schooling." Comparative Professional Pedagogy 9, no. 2 (June 1, 2019): 74–79. http://dx.doi.org/10.2478/rpp-2019-0021.
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Abstract This article presents the results of scientific-pedagogical research, which consisted in analyzing the American experience of the Dalton plan in the schooling of the Netherlands, the ranking surveys according to strict criteria, and the implementation of an adapted version of the original American pedagogical model of the Dalton Plan in the schooling of Holland; characterizing the features of the introduction of the Dalton Plan into the Dutch educational systems. While researching the works of M. Montessory, H. Parkhurst and D. Lager, had been examined as the main source of the study. The archival documents of the biggest collection of Helen Parkhurst papers of the Archive of University of Wisconsin Stevens Point had been analyzed. It was studied that American experience of the Dalton Plan is top ranked among private institutions of the country. It is obvious that after the United States, the country of the Dalton Plan origin, the continental Europe and Holland have a dominant position regarding the implementation of the Dalton plan in the educational systems. It is stated that schools implementing the Dalton Plan are united in recognizing the fact that such a pedagogical model ensures the development of the student’s individuality and his social experience. The special advantage the Dalton students obtain is the ability to use different approaches and sources in seeking information that is necessary for the organization and achievement of their own research. The ideas of the Dalton Plan can be justified in the light of modern theory and research. The Dalton Plan was successfully implemented into the primary and secondary schools of the Netherlands ranked the counrty11th in the world education survey. The Dalton Plan philosophy became one of the components of the complicated Dutch educational system.
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Sharma, Gunjan, and Biplob Koch. "IN VIVO THERAPEUTIC EFFICACY OF TWO RUTHENIUM COMPLEXES AND TUMOR REGRESSION IN DALTON’S LYMPHOMA ASCITES TUMOR MODEL." International Journal of Pharmacy and Biological Sciences 6, no. 3 (July 1, 2016): 121–27. http://dx.doi.org/10.21276/ijpbs.2016.6.3.14.
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Ramelan, Soetomo. "Peranan Notaris dalam Pembangunan Hukum." Jurnal Hukum & Pembangunan 16, no. 4 (June 14, 2017): 352. http://dx.doi.org/10.21143/jhp.vol16.no4.1209.
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Untuk sekedar memberikan gambaran mengenai peranan notaris dalam pembangunan hukum nasional kiranya para notaris sebagai anggota masyarakat Indonesia terpanggil untuk mengetahui dan memahami ketetapan-ketetapan Majelis Permusyawaratan Rakyat, sebagai suatu lembaga tertinggi negara yang berwenang menetapkan Garis-garis Besar Haluan Negara, termasuk dalam pembangunan hukum nasional, kebijaksanaan-kebijaksanaan mana dituangkan dalarn Ketetapan-ketetapan MPR. Dalarn salah satu ketetapannya, yakni TAP MPR/IV/1973 yang kemudian dirumuskan lebih lanjut di dalam Repelita II Bab 27 telah digariskan bahwa pembangunan hukum harus diarahkan pada tiga (3) sasaran pokok, yakni yang meliputi materi atau substansi hukum, pelaksana hukum dan masyarakat yang menjadisasaran pembangunan hukum.
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Li, Jin Kui, Hua Zhong Sun, and Xia Li. "Landslide Machanism in Xinghai Zhong Long Yuan and Its Reinforcement Technology." Advanced Materials Research 671-674 (March 2013): 60–64. http://dx.doi.org/10.4028/www.scientific.net/amr.671-674.60.
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The landslide is a global geological disasters, causing casualties and huge economic losses. This paper, the Dalian Xinghai Zhong Long Yuan landslides treatment project, analysis of landslides generated by internal causes and predisposing factors, obtained a landslide failure mechanism, and the causes of slope cutting, improve cut flood drainage structures, prestressed anchor Mississauga solid technical measures. The construction process for top of the hill horizontal displacement, deep horizontal displacement and anchor bearing capacity monitoring results show that the landslide control program is correct and effective measures to achieve the desired effect, made landslides governance success to reference for landslide control work for the Dalian region and the coastal cities.
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Wu, Haifeng, Spero Cataland, Michael Bissell, and Ming Jin. "A Rapid Test for the Diagnosis of Thrombotic Thrombocytopenic Purpura Using SELDI-TOF-Mass Spectrometry." Blood 106, no. 11 (November 16, 2005): 2660. http://dx.doi.org/10.1182/blood.v106.11.2660.2660.
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Abstract Thrombotic Thrombocytopenic Purpura (TTP), a life-threatening microangiopathic thrombotic disorder, requires immediate diagnosis and plasma exchange therapy. Development of TTP is related to functional deficiency of a metalloprotease, ADAMTS13, that leads to accumulation of ultra large von Willebrand factor (vWF) and subsequent platelet thrombosis. Currently no clinical test is available for a rapid detection of functional ADAMTS13 activity. In this study, a recombinant vWF peptide containing the ADAMTS13 cleavage site and a 6 X Histidine tag was used as a substrate for ADAMTS13. ADAMTS13 cleaved the substrate in a dose-dependent manner, generating a ~7739 Dalton peptide containing a 6 X Histidine tag. This cleaved peptide, bound to an IMAC/Nickel ProteinChip, was quantified using Surface Enhanced Laser Desorption/Ionization Time-of-flight Mass Spectrometry (SELDI-TOF-MS). The assay is capable of quantifying ADAMTS13 activity as low as 2.5 % in plasma within 3–4 hours. When the cleaved peptide was quantified as a ratio of an internal control peptide, the test displayed excellent reproducibility, with an average inter-assay CV of < 33 %. Further validation of the test in healthy donors (n=39) revealed normal ADAMTS13 activity with a mean of 92.5% + 16.6. Sixteen patients with idiopathic TTP displayed mean ADAMTS13 activity of 1.73% + 3.62 at presentation, prior to any therapy. Further utility of this novel method includes functional determination of ADAMTS13 antibody titers in cases of acquired TTP. In summary, we have devised a novel SELDI-TOF-MS assay that offers a rapid, cost-effective, and functionally relevant test for timely diagnosis and management of TTP patients.
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Wang, Mark Y. L. "The disappearing rural-urban boundary: rural socioeconomic transformation in the Shenyang-Dalian region of China." Third World Planning Review 19, no. 3 (August 1997): 229. http://dx.doi.org/10.3828/twpr.19.3.g38371x1172g0318.
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Xu, H., W. Chen, J. Sun, and Z. Yuan. "Impact of magnetic ion exchange resin pretreatment on alleviating UF membrane fouling." Water Supply 11, no. 1 (March 1, 2011): 7–14. http://dx.doi.org/10.2166/ws.2011.002.
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The purpose of this study is to undestand the effect and mechanism of preventing ultrafiltration(UF) membrane fouling by using magnetic ion exchange resin (MIEX®) in terms of fractional compent and molecular weight of NOM. In the experiment, pretreatment decreasing trans-membrane pressure and preventing membrane fouling were studied. The result showed: when the MIEX® dosage reached 800 bed volume (BV), the polymeric aluminium chloride (PAC) dosage could be reduced to 14 mg/L, and the Trans-Membrane Pressure (TMP) could be recovered effectively after hydraulic flush. This pretreatment could remove most of the hydrophobic and hydrophilic charged organics as well as some neutral organics. Foulants of molecular weight (MW) <1000 dalton (Da) and 3000 Da < MW < 100,000 Da organics could be removed by 40.7% and 96.0%, respectively. By reducing pore blocking and membrane cake resistance, the ultrafiltration (UF) membrane reduced the total resistance of membrane. As a result, membrane fouling was alleviated and the water production ratio was enhanced.
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Fan, X. D., G. R. Stark, and B. R. Bloom. "Molecular cloning of a gene selectively induced by gamma interferon from human macrophage cell line U937." Molecular and Cellular Biology 9, no. 5 (May 1989): 1922–28. http://dx.doi.org/10.1128/mcb.9.5.1922.
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A cDNA clone encoding a gamma interferon (IFN-gamma)-inducible mRNA in human cells of the macrophage lineage was isolated and characterized. The corresponding gene, gamma.1, was selectively induced by IFN-gamma, responding a hundredfold better to IFN-gamma than to IFN-alpha. The induction was rapid and transient, with maximal mRNA accumulation at about 3 h and decline to the basal level after 48 h. Transcriptional activation could be detected as early as 5 min after IFN-gamma stimulation and accounted entirely for the mRNA accumulation. The induction of gamma.1 by IFN-gamma was cell-type restricted, being seen only in macrophages and endothelial cells. In addition, phorbol ester-induced differentiation of promyelocytic HL-60 cells and promonocytic THP-1 cells rendered the gamma.1 gene inducible by IFN-gamma. The 1.0-kilobase gamma.1 cDNA sequence encoded a small predicted polypeptide of 38 amino acids and had a conserved sequence associated with rapidly turning over mRNAs. In vitro translation of the gamma.1 transcript yielded a 4,000-dalton polypeptide.
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Fan, X. D., G. R. Stark, and B. R. Bloom. "Molecular cloning of a gene selectively induced by gamma interferon from human macrophage cell line U937." Molecular and Cellular Biology 9, no. 5 (May 1989): 1922–28. http://dx.doi.org/10.1128/mcb.9.5.1922-1928.1989.
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A cDNA clone encoding a gamma interferon (IFN-gamma)-inducible mRNA in human cells of the macrophage lineage was isolated and characterized. The corresponding gene, gamma.1, was selectively induced by IFN-gamma, responding a hundredfold better to IFN-gamma than to IFN-alpha. The induction was rapid and transient, with maximal mRNA accumulation at about 3 h and decline to the basal level after 48 h. Transcriptional activation could be detected as early as 5 min after IFN-gamma stimulation and accounted entirely for the mRNA accumulation. The induction of gamma.1 by IFN-gamma was cell-type restricted, being seen only in macrophages and endothelial cells. In addition, phorbol ester-induced differentiation of promyelocytic HL-60 cells and promonocytic THP-1 cells rendered the gamma.1 gene inducible by IFN-gamma. The 1.0-kilobase gamma.1 cDNA sequence encoded a small predicted polypeptide of 38 amino acids and had a conserved sequence associated with rapidly turning over mRNAs. In vitro translation of the gamma.1 transcript yielded a 4,000-dalton polypeptide.
Dissertations / Theses on the topic "Dalton Twp"
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Li, Li S. M. (Massachusetts Institute of Technology). "The incidence of popular complaints of farmers on land compensation : a case study of two villages in Dalian, Liaoning Province, China." Thesis, Massachusetts Institute of Technology, 2006. http://hdl.handle.net/1721.1/37671.
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Thesis (M.C.P.)--Massachusetts Institute of Technology, Dept. of Urban Studies and Planning, 2006.Includes bibliographical references (leaves 41-42).
The thesis analyzed the reason for the incidence of lodging popular complaints triggered by a land requisition in two villages in Dalian, Liaoning Province, China. The thesis only took the popular protests on land compensation as a background. The main topic was how charismatic leaders mitigated the dissatisfaction toward land compensation. A field research was performed during which intensive interviews were conducted with the villagers and village leaders concerned in the case. The possible factors of causing the different results of popular complaints were discussed. The factor of village leadership was studies in detail. The thesis explained the relationship between village leadership and the happening of complaints. By analyzing the results of interviews, four aspects of village leadership were specified: leadership and economic rewards, leadership and communication, leadership and social norms, and leadership and historic trajectory. The thesis showed that the case in the background of current China could only partially be predicted by the existing theories in western world. Further research need to be conducted specifically against the background of China.
by Li Li.
M.C.P.
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Fahleson, Tobias. "Derivation and application of response functions for nonlinear absorption and dichroisms." Doctoral thesis, KTH, Teoretisk kemi och biologi, 2017. http://urn.kb.se/resolve?urn=urn:nbn:se:kth:diva-218662.
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This thesis explores and expands upon theoretical means of quantifying a number of nonlinear spectroscopies, including two-photon absorption, resonant-inelastic x-ray scattering, Jones birefringence, and magnetic circular dichroism. On top of that, detailed information is given for the derivation and program implementation of damped cubic response functions. Complex-valued cubic response functions have been implemented in the quantum chemistry package DALTON, based on working equations formulated for an approximate-state wave function. An assessment of the implementation, such that for small frequencies the second-order hyperpolarizability should behave according to an analytic function that depends quadratically on the optical frequencies. It is demonstrated how two-photon absorption (TPA) can be described either through second-order transition moments or via the damped cubic response function. A few calculated TPA profiles are produced for a set of smaller molecules, in order to display the capability of the cubic response function in the x-ray frequency region. Resonance-inelastic x-ray scattering (RIXS) is explored in a similar manner as two-photon absorption. It is shown how the second-order hyperpolarizability can represent RIXS in the limit of intermediate-state and final-state resonances. Complications emerging from the complex dispersion of the hyperpolarizability are discussed. Moreover, linear birefringences, with focus on the Jones birefringence, are investigated for noble gases, monosubstituted benzenes, furan homologues, and a pure acetonitrile liquid. A linear relation between the Jones birefringence and the empirical para-Hammett constant as well as the permanent electric dipole moment is presented. Estimations of three linear birefringences --- Kerr, Cotton--Mouton, and Jones ---are obtained by averaging over a set of liquid snapshots. The Jones effect for acetonitrile turns out to be unusually large inmparison to the other two investigated linear birefringences. The final chapter of the thesis investigates magnetically induced circular dichroism (MCD). A question regarding relative stability of the first set of excited states for DNA-related molecular systems is resolved through MCD by exploiting the signed nature of circular dichroisms. Furthermore, to what extent solvent contributions affect MCD spectra is explored. The effect on uracil MCD spectrum due to thionation is studied, for which the degree of redshifting for systems 2-thiouracil and 4-thiouracil can be seen to be addative as compared to the 2,4-dithiouracil system.QC 20171129
Books on the topic "Dalton Twp"
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Dalton, William. The Dalton journal: Two whaling voyages to the South Seas, 1823-1829. [Canberra]: National Library of Australia, 1990.
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Bedock, Camille. Why Study Bundles of Reforms? Oxford University Press, 2017. http://dx.doi.org/10.1093/oso/9780198779582.003.0002.
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This chapter starts by presenting the numerous conceptual and empirical arguments that have been put forward suggesting that political elites in Western European democracies have been trapped in areas of turbulence for the last two decades, with this taking the form of a general ‘erosion of political support’ (Dalton 2004). This perceived crisis of consolidated democracies has led to a broad debate on democratic institutions. The chapter then presents the dependent variable studied in this book, the bundle of reforms. The chapter commonly refers to ‘institutional systems’. The starting point, based on the existing literature and specifically on Lijphart’s work, is that democratic institutions evaluated together constitute a system. As a consequence, democratic reforms should also be studied taking into account the systemic nature of democratic institutions. The bundle of reforms constitutes a relevant unit of analysis with which to analyse reforms affecting multiple dimensions of the institutions simultaneously.
Book chapters on the topic "Dalton Twp"
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Boyd, Taylor. "Education Reform in Ontario: Building Capacity Through Collaboration." In Implementing Deeper Learning and 21st Education Reforms, 39–58. Cham: Springer International Publishing, 2020. http://dx.doi.org/10.1007/978-3-030-57039-2_2.
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Abstract The education system of the province of Ontario, Canada ranks among the best in the world and has been touted as a model of excellence for other countries seeking to improve their education system. In a system-wide reform, leaders used a political and professional perspective to improve student performance on basic academic skills. The school system rose to renown after this reform which moved Ontario from a “good” system in 2000 to a “great” one between 2003 and 2010 (Mourshed M, Chijioke C, Barber M. How the world’s most improved school systems keep getting better, a report McKinsey & Company. Retrieved from https://www.mckinsey.com/industries/social-sector/our-insights/how-the-worlds-most-improved-school-systems-keep-getting-better, (2010)). Premier Dalton McGuinty arrived in office in 2003 with education as his priority and was dubbed the “Education Premier” because of this mandate. His plan for reform had two primary goals: to improve student literacy and numeracy, and to increase secondary school graduation rates. McGuinty also wanted to rebuild public trust that had been damaged under the previous administration. The essential element of Ontario’s approach to education reform was allowing educators to develop their own plans for improvement. Giving responsibility and freedom to educators was critical in improving professional norms and accountability among teachers (Mourshed M, Chijioke C, Barber M. How the world’s most improved school systems keep getting better, a report McKinsey & Company. Retrieved from https://www.mckinsey.com/industries/social-sector/our-insights/how-the-worlds-most-improved-school-systems-keep-getting-better, (2010)) and the sustained political leadership throughout the entire reform concluding in 2013 provided an extended trajectory for implementing and adjusting learning initiatives. The Ministry of Education’s Student Achievement Division, which was responsible for designing and implementing strategies for student success, took a flexible “learning as we go” attitude in which the reform strategy adapted and improved over time (Directions Evidence and Policy Research Group. The Ontario student achievement division student success strategy evidence of improvement study. Retrieved from http://www.edu.gov.on.ca/eng/research/EvidenceOfImprovementStudy.pdf, (2014)). This chapter will discuss influences on the reform design and key components of strategies to support student and teacher development and build a relationship of accountability and trust among teachers, the government and the public. The successes and shortcomings of this reform will be discussed in the context of their role in creating a foundation for the province’s next steps towards fostering twenty-first century competencies in classrooms.
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Scerri, Eric. "From Dalton to the Discovery of the Periodic System." In A Tale of Seven Elements. Oxford University Press, 2013. http://dx.doi.org/10.1093/oso/9780195391312.003.0006.
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Our story begins, somewhat arbitrarily, in the English city of Manchester around the turn of the nineteenth century. There, a child prodigy by the name of John Dalton, at the tender age of fifteen is teaching in a school with his older brother. Within a few years, John Dalton’s interests have developed to encompass meteorology, physics, and chemistry. Among the questions that puzzle him is why the various component gases in the air such as oxygen, nitrogen, and carbon dioxide do not separate from each other. Why does the mixture of gases in the air remain as a homogeneous mixture? As a result of pursuing this question, Dalton develops what is to become modern atomic theory. The ultimate constituents of all substances, he supposes, are hard microscopic spheres or atoms that were first discussed by the ancient Greek philosophers and taken up again by modern scientists like Newton, Gassendi, and Boscovich. But Dalton goes a good deal further than all of these thinkers in establishing one all-important quantitative characteristic for each kind of atom, namely its weight. This he does by considering quantitative data on chemical experiments. For example, he finds that the ratio for the weight in which hydrogen and oxygen combine together is one to eight. Dalton assumes that water consists of one atom of each of these two elements. He takes a hydrogen atom to have a weight of 1 unit and therefore reasons that oxygen must have a weight of 8 units. Similarly, he deduces the weights for a number of other atoms and even molecules as we now call them. For the first time the elements acquire a quantitative property, by means of which they may be compared. This feature will eventually lead to an accurate classification of all the elements in the form of the periodic system, but this is yet to come. Before that can happen the notion of atoms provokes tremendous debates and disagreements among the experts of Dalton’s day.
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Hess, Earl J. "Dalton and Resaca." In Fighting for Atlanta, 26–47. University of North Carolina Press, 2018. http://dx.doi.org/10.5149/northcarolina/9781469643427.003.0002.
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Confederate earthworks were located on high, dominating ridges during the first confrontation of the Atlanta campaign at Dalton. These positions were nearly impervious to direct attack even though they contained only light fieldworks. But the Federals could outflank them by using gaps located in those ridges well beyond the Confederate flanks. From the beginning of the campaign Sherman was able to use maneuver with judicious use of holding works to pry Johnston from strong positions with minimal loss. At Resaca, the next battle of the campaign, the Confederates had far less advantageous ground to defend and they failed to construct proper fortifications to compensate for that disadvantage. As a result they suffered heavy losses and were compelled to evacuate the position after only two days of fighting.
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Oriakhi, Christopher O. "Atomic Structure and Isotopes." In Chemistry in Quantitative Language. Oxford University Press, 2009. http://dx.doi.org/10.1093/oso/9780195367997.003.0007.
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John Dalton proposed his theory of the atom in 1808 based on experimental data and chemical laws known in his day. The theory states that: 1. All chemical elements are made up of tiny indivisible particles called atoms. 2. Atoms cannot be created or destroyed. Chemical reactions only rearrange the manner in which atoms are combined. 3. Atoms of the same element are identical in all respects and have the same masses and physical and chemical properties. Atoms of different elements have different masses as well as different physical and chemical properties. 4. Combination of elements to form a compound occurs between small, whole-number ratios of atoms. Dalton’s theory resulted in the formulation of the law of conservation of mass and the law of multiple proportions. In a chemical reaction matter is neither created nor destroyed. The mass of products is equal to the mass of the reactants. If two elements form more than one compound between them, the masses of one element that combine with a fixed mass of the second element are in a ratio of whole numbers. Nitrogen and oxygen combine to form different compounds such as NO, NO2, and N2O. According to this law the number of nitrogen to oxygen atoms in these compounds should be a simple ratio of two small whole numbers. This is one of the basic laws of stoichiometry, as we shall see in chapter 9. An atom consists of a central nucleus, which contains roughly 99.9% of the total mass of the atom, and a surrounding cloud of electrons. The nucleus is composed of two kinds of particles, the protons and the neutrons, which are collectively known as the nucleons. The proton is positively charged while the neutron is electrically neutral. The electrons have a negative charge and surround the nucleus in “shells” of definite energy levels. (Note: energy level will be discussed in chapter 10.) In a neutral (unreacted) atom, the number of electrons is equal to the number of protons, so the atom has a charge of zero.
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Kauffmann, C. M. "The Study of Medieval Art I: 1900–50." In A Century of British Medieval Studies. British Academy, 2007. http://dx.doi.org/10.5871/bacad/9780197263952.003.0028.
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This chapter examines the history of the study of medieval art in Great Britain during the first half of the twentieth century. Before 1932, no British university offered an honours degree course in the history of art. In the case of the British Academy, art did not figure in any of its sections until 1923 when the title of Section Two was changed to Medieval and Modern History and Archaeology and Art. Three fellows of this section include M.R. James, G.F. Warner and O.M. Dalton. This chapter also highlights the contributions of continental art historians to the development of British medieval studies. They include Hugo Buchtal, Otto Demus and Ernst Kitzinger.
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Scerri, Eric. "Discoverers of the Periodic System." In The Periodic Table. Oxford University Press, 2019. http://dx.doi.org/10.1093/oso/9780190914363.003.0008.
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The periodic system was not discovered by Dmitri Mendeleev alone, as is commonly thought, or even just by Mendeleev and Julius Lothar Meyer. It was discovered by as many as five or six individuals at about the same time, in the decade of the 1860s, following the rationalization of atomic weights at the Karlsruhe conference. It became apparent by the middle of the nineteenth century that something needed to be done to resolve the widespread confusion over equivalent and atomic weights. Amedeo Avogadro had already proposed a solution to Gay-Lussac’s law that preserved John Dalton’s indivisible elemental particles. Recall that Gay-Lussac had observed that volumes of gases entering into chemical combination and their gaseous products are in a ratio of small integers. Dalton had refused to accept this viewpoint because it implied that atoms appeared to divide in some instances, such as the combination of hydrogen and oxygen to create steam. Avogadro had suggested that such “atoms” must be diatomic; that is, in their most elemental form they must be double. Thus, the oxygen atom was not dividing; rather, it was an oxygen molecule, which consisted of two oxygen atoms, that was coming apart. Unfortunately, the terms in which Avogadro expressed his views were rather obscure and failed to make much impression on the chemists of the day. Two exceptions were the French physicist and chemist André Ampère and the Alsatian chemist Charles Gerhardt, both of whom adopted the view that elemental gases were composed of diatomic molecules. One consequence of the general refusal to recognize the existence of diatomic molecules as the ultimate “atoms” of gaseous elements was that, as mentioned in chapter 2, the confusion between equivalent weights and atomic weights continued to reign. Although the relative weights of oxygen to hydrogen in water are approximately 8 to 1, the relative weight of the oxygen atom to the hydrogen atom takes on values of 8 or 16 depending on what one considers the correct formula for water to be.
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Voskuil, Lynn. "From Specimen to System." In Ecological Form, 161–81. Fordham University Press, 2018. http://dx.doi.org/10.5422/fordham/9780823282128.003.0009.
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The discipline of nineteenth-century botany was central both to the British imperial project and to the development of global theory. This article shows how the work of botanist Joseph Dalton Hooker (1817–1911) advanced certain concepts of globalization by exploring scale relationships in two mid-century texts—a systematic botany, Flora Indica (1855), and a travel narrative, Himalayan Journals (1854)—and by analyzing in particular the methodologies that link individual botanical species and their global distribution. In doing so, he drew upon tropes of the sublime and related aesthetic techniques to raise crucial hermeneutical questions and to perform an important scale critique. His contributions underscore the need for new scale critiques in the humanities today and the recognition that such critiques have significant antecedents in the work of nineteenth-century writers and scientists.
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Blackmore, R. D. "Chapter LV: Getting into Chancery." In Lorna Doone. Oxford University Press, 2008. http://dx.doi.org/10.1093/owc/9780199537594.003.0057.
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TWO of the Devonshire officers (Captains Pyke and Dallan) now took command of the men who were left, and ordered all to go home again, commending much the bravery which had been displayed on all sides, and the loyalty to the King, and the English...
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Lowery, Malinda Maynor. "A Creative State, Not a Welfare State." In The Lumbee Indians, 202–36. University of North Carolina Press, 2018. http://dx.doi.org/10.5149/northcarolina/9781469646374.003.0008.
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Lumbee advocates believed that Lumbees should harness the full power of self-determination provided by the federal government. Federal recognition does not legitimize a tribe’s identity, but it does give a tribe’s inherent sovereignty a unique place within the American political system. This chapter outlines the Lumbee fight for federal recognition throughout the late twentieth and early twenty-first centuries. Opposition came from the federal government, Washington political infighting, and other Indian tribes. Despite disappointment at the federal level, Lumbee organizations worked together to create a tribal government and constitution for the Lumbee people, as well as debated with each other about how best to do that. The topic of gaming was particularly controversial. Eventually Lumbees decided on an electoral system of government with representation on a district basis. The Lumbee constitution defined two important aspects of Lumbee identity: kinship and place.Important players in the Lumbee fight for sovereignty included Arlinda Locklear, Julian Pierce, Helen Maynor Schierbeck, and Dalton Brooks.
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Li, Chen, Min Jiang, and Mark Yaolin Wang. "Collision between two public interests in housing demolition and relocation in Dalian, China." In Handbook on Space, Place and Law, 118–28. Edward Elgar Publishing, 2021. http://dx.doi.org/10.4337/9781788977203.00022.
Full textConference papers on the topic "Dalton Twp"
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Simone, E. R., T. A. Davies, N. A. Zabe, S. M. Greenberg-seperaky, and N. E. Larsen. "EARLY PLATELET-THROMBIN RECEPTORS AND THEIR FUNCTIONS." In XIth International Congress on Thrombosis and Haemostasis. Schattauer GmbH, 1987. http://dx.doi.org/10.1055/s-0038-1643730.
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Human platelets possess less than 1000 high affinity [Kd=10-9]and 50-100,000 receptors of lower [Kd=10-7] affinity for o(α-thrombin. The selective derivatization of thrombin with the bifunctional crosslinking agent, DNCO, has enabled us to identify these receptorsvia covalent binding of either active siteinhibited tosyllyslmethylketothrombin (TLCK-T) or active Ctf-thrombin (T).Kinetic studies of the inhibition of the platelet-thrombin response by covalently and noncovalently bound TLCK-T have helped to elucidate the roles of the high and low affinity thrombin receptors. The activation parameters examined were initial membrane depolarization, cytoplasmic alkalinization,dense granule secretion of serotonin and lysosomal secretion of β-glucuronidase.Isolation and characterization of the thrombin receptors after covalent photocoupling of the TLCK-T or active T- were performed after solubilization by gel filtration. The intact, high affinity receptor moiety, a glycoprotein, has an approximate molecular weight of∽lSO.OOO daltons; occasionally this protein is found as a dimer of ∽360,000 daltons. When exposed to o(α-T the receptor undergoes proteolysis, leaving a protein of∽80,000 daltons and releasing the remaining glycoprotein into the medium.Higher doses of active T have been shown to bind with lower affinity to a larger protein of approximate molecular weight 600,000 daltons anda smaller protein of 46,000 daltons. Both proteins are nonsusceptible to thrombin proteolysis. Reduction and alkylation of the600,000 dalton complex yielded two and possibly three high molecular weight components (200,000, 160,000, and possibly 145,000daltons) which may correspond to previously suggested GP-Ia and GP-Ib of the GP-I complex. Under different solubilization conditions, two other membrane proteins have been found to be part of the GP-I complex; one which is not a glycoprotein, GP-Ic, while the other is associated with the glycocalyx and is called glycocalicin. Glycocalicin and GP-Icdo inhibit thrombin binding,implying that the low affinity receptor is indeed the previously suggested GP-I complex and does not appear to be directly involved withplatelet activation.Examination of the effect of dose and duration of incubation with non-covalently binding TLCK-T on subsequent α-thrombin response suggests the existence of positive cooperativity among thrombin receptors.Although TLCK-T has the same affinity for platelets (Kd) as T , the rateof binding and therefore that of dissociation are lower. Thus for incubation times of 1 minute or less with up to a 2x saturating TLCK-T dose, the subsequent depolarization response to a saturating T dose was enhanced. Exposure to higher TLCK-T (5x saturating)doses led to significant inhibition.Verification of the potentiation observed in noncovalent TLCK-T studies was performed using TLCK-T covalently bound to the platelet receptor with DNCO. Several hundred thrombin molecules were bound to the platelet when a subsaturating dose of TLCK-T(0.0025 U/ml) was used to crosslink, whileseveral thousand resulted with a saturating (0.05 U/ml) TLCK-T dose. Positive cooperativity was observed with low αT doses (0.005 U/ml) when several hundred high affinity receptors are blocked. The parameters studied which exhibited this positive cooperativity were depolarization, pH change and serotonin secretion, α-Glucuronidase secretion was normal. The presence and degreeof enhancement were donor-variableand suggest different threshhold thrombin dose requirements. The enhancement observed can be attributed to either an increased rate of binding (increased affinity) or to an increased number of exposed binding sites. Since little difference was found between the number of TLCK-T molecules bound after30 versus 60 seconds, we conclude that thepotentiation is more likely due to an increased number of exposed binding sites. Results from covalent crosslinks using a fluorescein and rhodamine labeled-TLCK-T and the fluorescence activated cellsorter support this hypothesis. The sensitization of the high affinity binding sitesby partial occupancy implies these bindingsites are responsible for depolarization, pH change and dense granule secretion (the rapid initial activation response), while βglucuronidase secretion, a secondary response, is otherwise controlled.
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Huzoor-Akbar, H., and Khursheed Anwer. "EVIDENCE THAT ABNORMAL PLATELET AGGREGATION IN SPONTANEOUSLY HYPERTENSIVE RATS IS LINKED WITH PHOSPHOINOSITIDES TURNOVER AND PHOSPHORYLATION OF 47,000 DALTON PROTEIN." In XIth International Congress on Thrombosis and Haemostasis. Schattauer GmbH, 1987. http://dx.doi.org/10.1055/s-0038-1643810.
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We have shown earlier that abnormal platelet aggregation in spontaneously hypertensive rats (SHR) is not caused by prostaglandins (Thromb. Res. 41, 555-566, 1986). In this study platelets from SHR and normotensive (Wistar Kyoto, WKY) rats were used to examine the role of phosphoinositides (Pins) and protein phosphorylation in increased platelet activation in hypertension. Thrombin (0.05 U/ml) induced rapid hydrolysis of phosphatidylinositol-4,5-bis-phosphate (PIP2), phosphatidyl-inositol-4-phosphate (PIP), and phosphatidylinositol (PI) in (32p)-pO4 labeled platelets. However, significantly greater hydrolysis of PIP2 and PI was seen in SHR platelets than in WKY platelets (see Table). Thrombin also caused two- to three-fold increased accumulation of phosphatidic acid (PA) in SHR platelets than in WKY platelets (see Table).Thrombin caused phosphorylation of 18,000 Dalton (P18) and 47, Dalton (P47) proteins in SHR and WKY Platelets. Significantly increased phosphorylation of P47 was seen at 5, 15, 60 and 240 seconds of incubation with thrombin in SHR platelets (60%, 68%, 98% and 91%) than in WKY platelets (13%, 37%, 44% and 47%). The extent of P18 phosphorylation was same in both SHR and WKY platelets. Aspirin (500 uM) did not affect phosphorylation of P47 or P18 in SHR or WKY Platelets. These data lead us to suggest that increased turnover of Pins and increased phosphorylation of P47 are involved in abnormal platelet aggregation in SHR (Supported in part by the COHC grant #86-01-A and the Ohio University College of Osteopathic Medicine).
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Brace, L. D., J. Fareed, and D. Hoppensteadt. "HEPARIN-INDUCED PLATELET AGGREGATION (H-IPA): DOSE/RESPONSE RELATIONSHIPS FOR TWO LOW MOLECULAR WEIGHT (LMW)HEPARIN PREPARATIONS (CY 216 and CY 222)." In XIth International Congress on Thrombosis and Haemostasis. Schattauer GmbH, 1987. http://dx.doi.org/10.1055/s-0038-1642870.
Full textAbstract:
We have previously demonstrated that unfractionated heparin causes platelet aggregation (>50%) in about 40% of normal healthy donors tested. H-IPA occurs in a dose-dependent manner and can be inhibited by antogonists of the thromboxane pathway. Using a LMW heparin preparation (PK 10169) and fractions of this agent separated on the basis of molecular weight (MW) by gel permeation chromatography, we showed that H-IPA was dependent upon the MW of the agents tested. In order to further examine this MW dependence, we tested two other LMW heparin preparations, CY 216 (Mol. wt: 5600) and CY 222 (mol. wt: 3800), and 9 subfractions of each of these agents separated on the basis of MW. Blood was drawn from the same donors whose platelets aggregated when heparin was added to their platelet-rich plasma (PRP), and placed into citrate anticoagulant. PRP was prepared, various concentrations of the agents or their fractions were added and aggregation was monitored for 40 minutes at 37°C. Dose/response curves were constructed from the data obtained with each agent. Compared to unmodified heparin with Mr = 15,000 daltons (D), the dose/response curves for CY 216 (Mr = 5000 D) and CY 222 (Mr = 3,500 D) were shifted progressively down and to the right. Dosq' response curves for each of the fractions of CY 216 and CY 222 demonstrated that as the molecular weight of the fractions decreased, the dose/response curves were also shifted progressively down and to the right. These results indicate that as MW decreases, higher concentrations of the fractions are required to cause aggregation, and the maximum aggregation obtained decreases. Fractions with MW less than 2,500 daltons caused aggregation only at concentrations exceeding supra therapeutic range. Since heparin and LMW fractions have inhibitory activity to the activated clotting factors Ila and Xa and LMW fractions have higher anti-Xa than anti-IIa activity, we measured these activities and attempted to correlate them with the ability to cause H-IPA. No correlation between AXa and H-IPA was found. We conclude that the ability to cause H-IPA is an inherent property of heparin and is molecular weight dependent.
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Siddigui, F. A., and E. C. Y. Lian. "PLATELET AGGLUTINATING PROTEIN P37 FROM A THROMBOTIC THROMBOCYTOPENIC PURPURA PLASMA FORMS A COMPLEX WITH IMMUNOGLOBULIN G." In XIth International Congress on Thrombosis and Haemostasis. Schattauer GmbH, 1987. http://dx.doi.org/10.1055/s-0038-1644589.
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A 37-KDa platelet agglutinating protein (PAP p37) from the plasma of a patient with thrombotic thrombocytopenic purpura (TTP), has been shown to be present in a subset of TTP patients. The platelet agglutination induced by PAP p37 has been demonstrated to be inhibited by igG from normal adults. To elucidate the mechanism of inhibition of IgG, the interaction between PAP p37 and IgG was studied. The complex formation was demonstrated by the binding of fluid-phase IgG to adsorbed PAP using enzyme-linked immunosorbent assay. The binding was specific, concentration dependent and saturable. The IgG covalently cross-linked to Sepharose 4B bound 125I-PAP but not to 125I-fibrinogen. Sucrose density gradient ultracentrifugation of a mixture of 125I-PAP and IgG also revealed the fluid phase complex formation with a sedimentation value of 19S. Complexes of molecular weight ranging from 180,000 to over 350,000 daltons were also detected by molecular sieve chromatography. The specific complex formation between PAP p37 and IgG is likely to account for the in vitro inhibition of TTP plasma-induced agglutination and , at least partly, the in vivo successful treatment with IgG-containing normal plasma.
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Wernet, P., M. Haurand, W. Nüsing, E. M. Schneider, K. Jaschonek, and V. Ullrich. "Production and characterization of a murine monoclonal antibody against human thromboxane synthetase." In XIth International Congress on Thrombosis and Haemostasis. Schattauer GmbH, 1987. http://dx.doi.org/10.1055/s-0038-1643382.
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Eicosanoids appear to have an important role in the actual momentary regulation of tissue blood flow. The function of constricting blood vessels by affecting the vascular tone has been assigned to thromboxane. Thromboxane synthetase, the enzyme responsible for the conversion of Prostaglandin-H2 into thromboxane A2, has been shown to be present in platelets, lung fibroblasts and the brain. Recently, thromboxane synthetase has been totally purified. The enzyme isolated from platelets appears to have a molecular weight of 58,800 Dalton and to belong to the group of cytochrome P450 proteins. In order to make a monoclonal antibody against thromboxane synthetase, BALB/c mice were injected four times i.m. with 10, 5, 5 and 4 μg of the platelet purified enzyme in complete Freund's adjuvant. The serum antibody titer against thromboxane synthetase in an ELISA was higher than 1:1000 after the second boost. One mouse received a fifth i.v. injection of 10 μg of the purified enzyme. One monoclonal antibody of the several hundreds of hybridomas screened in an ELISA revealed specific activity against thromboxane synthetase with a titer of 1:512 present in the culture supernatant. After recloning this reagent, called T0300, was used for the preparation of an immunoaffinity column, where it also reacted specifically. In immunoprecipitation experiments T0300 was able to precipitate a 58,000 D molecule. Also the biological activity of thromboxane synthetase could be blocked by monoclonal antibody T0300. In addition this reagent was employed in indirect immunofluorescence on leukemic cells employing a FACS IV cytofluorometer. Here specific staining of two megacaryocytic blast cell populations could be demonstrated. Thus T0300 appears to be a monoclonal antibody against human thromboxane synthetase.
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Cool, D. E., and R. T. A. MacGillivray. "CHARACTERIZATION OF THe HUMAN FACTOR XII GENE." In XIth International Congress on Thrombosis and Haemostasis. Schattauer GmbH, 1987. http://dx.doi.org/10.1055/s-0038-1642800.
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Surface activation of the plasma systems involved with coagulation, fibrinolysis, renin formation and kinin generation involves factor XII (Hageman factor). This protein is a 76,000 dalton glycoprotein which circulates in plasma as an inactive form of a serine protease. A human liver cDNA coding for factor XII was used to screen a human genomic phage library. Two overlapping clones were isolated, XHXII27 and XHXII76, and contain the entire gene for human factor XII. The gene is 13.5 Kbp in length and consists of 14 exons and 13 introns. The transcriptional start site of the mRNA was determined using S1 mapping and primer extension analysis. The results indicate that the 5′ untranslated end of the mRNA has a leader sequence of 47 bp and is not interrupted by an intron in the gene. DNA sequence analysis of the region upstream of the transcriptional start site does not contain TATA or CAAT sequences, which are often found in other genes transcribed by RNA polymerase II. The positions of the introns in the coding sequence separate the protein into domains which are homologous to similar regions found in fibronectin and tissue-type plasminogen activator. Furthermore, wherever protein homologies are found, the positions of the introns in the triplet codon occur in the same reading frame as in the tissue-type plasminogen activator, urokinase plasminogen activator and factor XII genes. The intron/exon organization of the factor XII gene is different to the organization of other coagulation genes such as prothrombin, factor IX and factor X. Therefore, factor XII appears to have evolved as a member of the plasminogen activator family of genes rather than as a member of the clotting factor gene family.
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kariyone, S., H. kambayashi, T. satoh, T. uchida, H. ohto, and H. maeda. "A NEW MONOCLONAL ANTIBODY TO PLATELET MEMBRANE GLYCOPROTEINIV: EXPRESSION OF GLYCOPROTEIN IV ON PLATELETS, MEGAKRYOCYTES AND ERYTHROBLASTS." In XIth International Congress on Thrombosis and Haemostasis. Schattauer GmbH, 1987. http://dx.doi.org/10.1055/s-0038-1643531.
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A New monoclonal antibody, designated as TP85, was produced by fusion of the X63.Ag8.653 murine myeloma cell line with splenocytes from BALB/C mice immunized with washed human platelets. TP85 monoclonal antibody precipitated a single petide of 97,000 daltons in both reduced and nonreduced states by immune precipitation of 125I-labelled solubilized membrane. An isoelectric point was around pH 5.0. The antibody was IgG2b in isotype, as determined by the Ouchterlony immunodiffusion method.The reactivity of TP85 was examined by using indirect immuno-fluorescent assays and ABC immunoperoxidase method. TP85 reacted with platelets, megakaryocytes and erythroblasts from normal human and patients with myeloproliferative disorders, but not with lymphocytes, granulocytes and other bone marrow cells. In a panel of cultured cell line, only 5-10% cells of K652 myeloid/ erythroid cell line were positive, but other cell lines, including common ALL(Reh), T lymphoid(Molt-3, CCRF-CEM), B lymphoid(Raji ,Daudi), myeloid(KG-l, HL-60) and monoblastoid(U937, THP-l) cell lines, were all negative.TP85 did not inhibit platelet aggregations induced by ADP, collagen, epinephrine and ristocetin while TP80 which was an antibody for GPIIb/IIIa inhibited these aggregations except induced by ristocetin.It is concluded that glycoprotein IV, which is immunoprecipitated by TP85, may exist not only on platelet membrane, but also on megakaryocytes and erythroblasts, and has no role on platelet aggregation.
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Sadler, J. Evan. "THE MOLECULAR BIOLOGY OF VON WILLEBRAND FACTOR." In XIth International Congress on Thrombosis and Haemostasis. Schattauer GmbH, 1987. http://dx.doi.org/10.1055/s-0038-1643930.
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Human von Willebrand factor (vWF) is a plasma glycoprotein that is synthesized by endothelial cells and megakaryocytes, and perhaps by syncytiotrophoblast of placenta. The biosynthesis of vWF is very complex, involving proteolytic processing, glycosyla-tion, disulfide bond formation, and sulfation. Mature vWF consists of a single subunit of ∼ 250,000 daltons that is assembled into multimer ranging from dimers to species of over 10 million daltons. vWF performs its essential hemostatic function through several binding interactions, forming a bridge between specific receptors on the platelet surface and components of damaged vascular subendothelial connective tissue. Inherited deficiency of vWF, or von Willebrand disease (vWD), is the most common genetically transmitted bleeding disorder worldwide. The last two years has been a time of very rapid progress in understanding the molecular biology of vWF. Four research groups have independently isolated and sequenced the 9 kilobase full-length vWF cDNA. The predicted protein sequence has provided a foundation for understanding the biosynthetic processing of vWF, and has clarified the relationship between vWF and a 75-100 kilodalton plasma protein of unknown function, von Willebrand antigen II (vWAgll)/ vWAgll is co-distributed with vWF in endothelial cells and platelets, and is deficient in patients with vWD. The cDNA sequence of vWF shows that vWAgll is a rather large pro-peptide for vWF, explaining the biochemical and genetic association between the two proteins. vWF has a complex evolutionary history marked by many separate gene segment duplications. The primary structure of the protein contains four distinct types of repeated domains present in two to four copies each. Repeated domains account for over 90 percent of the protein sequence. This sequence provides a framework for ordering the functional domains that have been defined by protein chemistry methods. A tryptic peptide from the amino-terminus of vWF that overlaps domain D3 binds to factor VIII and also appears to bind to heparin. Peptides that include domain A1 bind to collagens, to heparin, and to platelet glycoprotein Ib. A second collagen binding site appears to lie within domain A3. The vWF cDNA has been expressed in heterologous cells to produce small amounts of functionally and structurally normal vWF, indicating that endothelial cells are not unique in their ability to process and assemble vWF multimers. Site-directed mutagenesis has been used to show that deletion of the propeptide of vWF prevents the formation of multimers. Cloned cDNA probes have been employed to isolate vWF genomic DNA from cosmid and λ-phage libraries, and the size of the vWF gene appears to be ∼ 150 kilobases. The vWF locus has been localized to human chromosome 12p12—pter. Several intragenic RFLPs have been characterized. With them, vWF has been placed on the human genetic linkage map as the most telomeric marker currently available for the short arm of chromosome 12. A second apparently homologous locus has been identified on chromosome 22, but the relationship of this locus to the authentic vWF gene is not yet known. The mechanism of vWD has been studied by Southern blotting of genomic DNA with cDNA probes in a few patients. Three unrelated pedigrees have been shown to have total deletions of the vWF gene as the cause of severe vWD (type III). This form of gene deletion appears to predispose to the development of inhibitory alloantibodies to vWF during therapy with cryoprecipitate. During the next several years recombinant DNA methods will continue to contribute our understanding of the evolution, biosynthesis, and structure-function relationships of vWF, as well as the mechanism of additional variants of vWD at the level of gene structure.
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Ding, Haoyu, Jun Zang, Dezhi Ning, Xuanlie Zhao, Qiang Chen, Chris Blenkinsopp, and Junliang Gao. "Evaluation of the Performance of an Integrated WEC Type of Breakwater System." In ASME 2019 38th International Conference on Ocean, Offshore and Arctic Engineering. American Society of Mechanical Engineers, 2019. http://dx.doi.org/10.1115/omae2019-95739.
Full textAbstract:
Abstract A new type of coastal structure is proposed to reduce construction-cost and construction-space by integrating wave energy converters (WECs) into breakwater system. To develop this type of system to be more stable and effective, this paper focuses on investigating and improving an existing concept of integrated WEC type of breakwater system using a numerical method based on OpenFOAM®. Validation of the numerical setup is conducted by comparing the numerical predictions with relevant experimental data collected in a wave tank at Dalian University of Technology. The integrated WEC type of breakwater system considered in this paper is a pile-restrained WEC-type dual-floating breakwater system. The two floating breakwaters in this system are constrained to heave motion independently and work as a heaving-oscillating buoy type of WECs driven by a linear power take-off damping system (PTO system). Two parameters including wave transmission factor and capture width ratio (which is defined as the ratio of absorbed wave power to the incident wave power in the device width) are studied and discussed in the paper. The range of effective frequencies (range with wave transmission factor KT < 0.5 and capture width ratio CWR > 0.2) is obtained to evaluate the performance of this system with regard to both breakwater and WEC. These results indicate that damping coefficient of PTO system and gap width between two floating bodies influence wave transmission factor and capture width ratio, and the range of effective frequencies can be improved by the appropriate damping coefficient and gap width.
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Cheng, Xiaofei, Yongxue Wang, Bing Ren, and Guoyu Wang. "Numerical Study of Hydrodynamic Forces on a Submarine Piggyback Pipeline Under Wave Action." In ASME 2012 31st International Conference on Ocean, Offshore and Arctic Engineering. American Society of Mechanical Engineers, 2012. http://dx.doi.org/10.1115/omae2012-83214.
Full textAbstract:
In the paper, a 2D numerical model is established to simulate the hydrodynamic forces on a submarine piggyback pipeline under regular wave action. The two-dimensional Reynolds-averaged Navier-Stokes equations with a κ-ω turbulence model closure are solved by using a three-step Taylor-Galerkin finite element method (FEM). A Computational Lagrangian-Eulerian Advection Remap Volume of Fluid (CLEAR-VOF) method is employed to simulate free surface problems, which is inherently compatible with unstructured meshes and finite element method. The numerical results of in-line force and lift (transverse) force on the piggyback pipeline for e/D = G/D = 0.25 and KC = 25.1 are compared with physical model test results, which are conducted in a marine environmental flume in the State Key Laboratory of Coastal and Offshore Engineering, Dalian University of Technology, China. It is indicated that the numerical results coincide with the experimental results and that the numerical model can be used to predict the hydrodynamic forces on the piggyback pipeline under wave action. Based on the numerical model, the surface pressure distribution and the motion of vortices around the piggyback pipeline for e/D = G/D = 0.25, KC = 25.1 are investigated, and a characteristic vortex pattern around the piggyback pipeline denoted “anti-phase-synchronized” pattern is recognized.