Journal articles on the topic 'Dalton Twp'

Abstract This article presents the results of scientific-pedagogical research, which consisted in analyzing the American experience of the Dalton plan in the schooling of the Netherlands, the ranking surveys according to strict criteria, and the implementation of an adapted version of the original American pedagogical model of the Dalton Plan in the schooling of Holland; characterizing the features of the introduction of the Dalton Plan into the Dutch educational systems. While researching the works of M. Montessory, H. Parkhurst and D. Lager, had been examined as the main source of the study. The archival documents of the biggest collection of Helen Parkhurst papers of the Archive of University of Wisconsin Stevens Point had been analyzed. It was studied that American experience of the Dalton Plan is top ranked among private institutions of the country. It is obvious that after the United States, the country of the Dalton Plan origin, the continental Europe and Holland have a dominant position regarding the implementation of the Dalton plan in the educational systems. It is stated that schools implementing the Dalton Plan are united in recognizing the fact that such a pedagogical model ensures the development of the student’s individuality and his social experience. The special advantage the Dalton students obtain is the ability to use different approaches and sources in seeking information that is necessary for the organization and achievement of their own research. The ideas of the Dalton Plan can be justified in the light of modern theory and research. The Dalton Plan was successfully implemented into the primary and secondary schools of the Netherlands ranked the counrty11th in the world education survey. The Dalton Plan philosophy became one of the components of the complicated Dutch educational system.

Untuk sekedar memberikan gambaran mengenai peranan notaris dalam pembangunan hukum nasional kiranya para notaris sebagai anggota masyarakat Indonesia terpanggil untuk mengetahui dan memahami ketetapan-ketetapan Majelis Permusyawaratan Rakyat, sebagai suatu lembaga tertinggi negara yang berwenang menetapkan Garis-garis Besar Haluan Negara, termasuk dalam pembangunan hukum nasional, kebijaksanaan-kebijaksanaan mana dituangkan dalarn Ketetapan-ketetapan MPR. Dalarn salah satu ketetapannya, yakni TAP MPR/IV/1973 yang kemudian dirumuskan lebih lanjut di dalam Repelita II Bab 27 telah digariskan bahwa pembangunan hukum harus diarahkan pada tiga (3) sasaran pokok, yakni yang meliputi materi atau substansi hukum, pelaksana hukum dan masyarakat yang menjadisasaran pembangunan hukum.

The landslide is a global geological disasters, causing casualties and huge economic losses. This paper, the Dalian Xinghai Zhong Long Yuan landslides treatment project, analysis of landslides generated by internal causes and predisposing factors, obtained a landslide failure mechanism, and the causes of slope cutting, improve cut flood drainage structures, prestressed anchor Mississauga solid technical measures. The construction process for top of the hill horizontal displacement, deep horizontal displacement and anchor bearing capacity monitoring results show that the landslide control program is correct and effective measures to achieve the desired effect, made landslides governance success to reference for landslide control work for the Dalian region and the coastal cities.

Abstract Thrombotic Thrombocytopenic Purpura (TTP), a life-threatening microangiopathic thrombotic disorder, requires immediate diagnosis and plasma exchange therapy. Development of TTP is related to functional deficiency of a metalloprotease, ADAMTS13, that leads to accumulation of ultra large von Willebrand factor (vWF) and subsequent platelet thrombosis. Currently no clinical test is available for a rapid detection of functional ADAMTS13 activity. In this study, a recombinant vWF peptide containing the ADAMTS13 cleavage site and a 6 X Histidine tag was used as a substrate for ADAMTS13. ADAMTS13 cleaved the substrate in a dose-dependent manner, generating a ~7739 Dalton peptide containing a 6 X Histidine tag. This cleaved peptide, bound to an IMAC/Nickel ProteinChip, was quantified using Surface Enhanced Laser Desorption/Ionization Time-of-flight Mass Spectrometry (SELDI-TOF-MS). The assay is capable of quantifying ADAMTS13 activity as low as 2.5 % in plasma within 3–4 hours. When the cleaved peptide was quantified as a ratio of an internal control peptide, the test displayed excellent reproducibility, with an average inter-assay CV of < 33 %. Further validation of the test in healthy donors (n=39) revealed normal ADAMTS13 activity with a mean of 92.5% + 16.6. Sixteen patients with idiopathic TTP displayed mean ADAMTS13 activity of 1.73% + 3.62 at presentation, prior to any therapy. Further utility of this novel method includes functional determination of ADAMTS13 antibody titers in cases of acquired TTP. In summary, we have devised a novel SELDI-TOF-MS assay that offers a rapid, cost-effective, and functionally relevant test for timely diagnosis and management of TTP patients.

The purpose of this study is to undestand the effect and mechanism of preventing ultrafiltration(UF) membrane fouling by using magnetic ion exchange resin (MIEX®) in terms of fractional compent and molecular weight of NOM. In the experiment, pretreatment decreasing trans-membrane pressure and preventing membrane fouling were studied. The result showed: when the MIEX® dosage reached 800 bed volume (BV), the polymeric aluminium chloride (PAC) dosage could be reduced to 14 mg/L, and the Trans-Membrane Pressure (TMP) could be recovered effectively after hydraulic flush. This pretreatment could remove most of the hydrophobic and hydrophilic charged organics as well as some neutral organics. Foulants of molecular weight (MW) <1000 dalton (Da) and 3000 Da < MW < 100,000 Da organics could be removed by 40.7% and 96.0%, respectively. By reducing pore blocking and membrane cake resistance, the ultrafiltration (UF) membrane reduced the total resistance of membrane. As a result, membrane fouling was alleviated and the water production ratio was enhanced.

A cDNA clone encoding a gamma interferon (IFN-gamma)-inducible mRNA in human cells of the macrophage lineage was isolated and characterized. The corresponding gene, gamma.1, was selectively induced by IFN-gamma, responding a hundredfold better to IFN-gamma than to IFN-alpha. The induction was rapid and transient, with maximal mRNA accumulation at about 3 h and decline to the basal level after 48 h. Transcriptional activation could be detected as early as 5 min after IFN-gamma stimulation and accounted entirely for the mRNA accumulation. The induction of gamma.1 by IFN-gamma was cell-type restricted, being seen only in macrophages and endothelial cells. In addition, phorbol ester-induced differentiation of promyelocytic HL-60 cells and promonocytic THP-1 cells rendered the gamma.1 gene inducible by IFN-gamma. The 1.0-kilobase gamma.1 cDNA sequence encoded a small predicted polypeptide of 38 amino acids and had a conserved sequence associated with rapidly turning over mRNAs. In vitro translation of the gamma.1 transcript yielded a 4,000-dalton polypeptide.

A cDNA clone encoding a gamma interferon (IFN-gamma)-inducible mRNA in human cells of the macrophage lineage was isolated and characterized. The corresponding gene, gamma.1, was selectively induced by IFN-gamma, responding a hundredfold better to IFN-gamma than to IFN-alpha. The induction was rapid and transient, with maximal mRNA accumulation at about 3 h and decline to the basal level after 48 h. Transcriptional activation could be detected as early as 5 min after IFN-gamma stimulation and accounted entirely for the mRNA accumulation. The induction of gamma.1 by IFN-gamma was cell-type restricted, being seen only in macrophages and endothelial cells. In addition, phorbol ester-induced differentiation of promyelocytic HL-60 cells and promonocytic THP-1 cells rendered the gamma.1 gene inducible by IFN-gamma. The 1.0-kilobase gamma.1 cDNA sequence encoded a small predicted polypeptide of 38 amino acids and had a conserved sequence associated with rapidly turning over mRNAs. In vitro translation of the gamma.1 transcript yielded a 4,000-dalton polypeptide.

Abstract. The aim of this work is to elucidate the impact of changes in solar irradiance and energetic particles vs. volcanic eruptions on tropospheric global climate during the Dalton Minimum (DM, 1780–1840 AD). Separate variations in the (i) solar irradiance in the UV-C with wavelengths λ < 250 nm, (ii) irradiance at wavelengths λ > 250 nm, (iii) in energetic particle spectrum, and (iv) volcanic aerosol forcing were analyzed separately, and (v) in combination, by means of small ensemble calculations using a coupled atmosphere-ocean chemistry-climate-model. Global and hemispheric mean surface temperatures show a significant dependence on solar irradiance at λ > 250 nm. Also, powerful volcanic eruptions in 1809, 1815, 1831 and 1835 significantly decrease global mean temperature by up to 0.5 K for 2–3 yr after the eruption. However, while the volcanic effect is clearly discernible in the southern hemispheric mean temperature, it is less significant in the Northern Hemisphere, partly because the two largest volcanic eruptions occurred in the SH tropics and during seasons when the aerosols were mainly transported southward, partly because of the higher northern internal variability. In the simulation including all forcings, temperatures are in reasonable agreement with the tree-ring-based temperature anomalies of the Northern Hemisphere. Interestingly, the model suggests that solar irradiance changes at λ < 250 nm and in energetic particle spectra have only insignificant impact on the climate during the Dalton Minimum. This downscales the importance of top-down processes (stemming from changes at λ < 250 nm) relative to bottom-up processes (from λ > 250 nm). Reduction of irradiance at λ > 250 nm leads to a significant (up to 2%) decrease of the ocean heat content (OHC) between the 0 and 300 m of depth, whereas the changes in irradiance at λ < 250 nm or in energetic particle have virtually no effect. Also, volcanic aerosol yields a very strong response, reducing the OHC of the upper ocean by up to 1.5%. In the simulation with all forcings, the OHC of the uppermost levels recovers after 8–15 yr after volcanic eruption, while the solar signal and the different volcanic eruptions dominate the OHC changes in the deeper ocean and prevent its recovery during the DM. Finally, the simulations suggest that the volcanic eruptions during the DM had a significant impact on the precipitation patterns caused by a widening of the Hadley cell and a shift of the intertropical convergence zone.

Abstract. The aim of this work is to elucidate the impact of changes in solar irradiance and energetic particles versus volcanic eruptions on tropospheric global climate during the Dalton Minimum (DM, AD 1780–1840). Separate variations in the (i) solar irradiance in the UV-C with wavelengths λ < 250 nm, (ii) irradiance at wavelengths λ > 250 nm, (iii) in energetic particle spectrum, and (iv) volcanic aerosol forcing were analyzed separately, and (v) in combination, by means of small ensemble calculations using a coupled atmosphere–ocean chemistry–climate model. Global and hemispheric mean surface temperatures show a significant dependence on solar irradiance at λ > 250 nm. Also, powerful volcanic eruptions in 1809, 1815, 1831 and 1835 significantly decreased global mean temperature by up to 0.5 K for 2–3 years after the eruption. However, while the volcanic effect is clearly discernible in the Southern Hemispheric mean temperature, it is less significant in the Northern Hemisphere, partly because the two largest volcanic eruptions occurred in the SH tropics and during seasons when the aerosols were mainly transported southward, partly because of the higher northern internal variability. In the simulation including all forcings, temperatures are in reasonable agreement with the tree ring-based temperature anomalies of the Northern Hemisphere. Interestingly, the model suggests that solar irradiance changes at λ < 250 nm and in energetic particle spectra have only an insignificant impact on the climate during the Dalton Minimum. This downscales the importance of top–down processes (stemming from changes at λ < 250 nm) relative to bottom–up processes (from λ > 250 nm). Reduction of irradiance at λ > 250 nm leads to a significant (up to 2%) decrease in the ocean heat content (OHC) between 0 and 300 m in depth, whereas the changes in irradiance at λ < 250 nm or in energetic particles have virtually no effect. Also, volcanic aerosol yields a very strong response, reducing the OHC of the upper ocean by up to 1.5%. In the simulation with all forcings, the OHC of the uppermost levels recovers after 8–15 years after volcanic eruption, while the solar signal and the different volcanic eruptions dominate the OHC changes in the deeper ocean and prevent its recovery during the DM. Finally, the simulations suggest that the volcanic eruptions during the DM had a significant impact on the precipitation patterns caused by a widening of the Hadley cell and a shift in the intertropical convergence zone.

Based on the background of Dalian subway running through bridge pile foundation, a 3d numerical model is built by the finite element software MIDAS/GTS in order to research the laws of the internal force and the displacement of the pile and soil during the Construction process. The outcome reflects that the sedimentation value of the top of the pile is bigger than others. Because the bigger thrust about the shield machine, the horizontal displacement of the pile is increasing at first and decreasing at last from a positive into a negative. Because of the loss of the soil, the soil beside the pile collapses and causes strong friction force. The surface sedimentation value which is near the central line of the tunnel is bigger than other place. This paper is of good reference roles in the similar underground engineering in Dalian.

The development status and trend of the patents related to sewage treatment technology in Dalian, China in the past decade may affect the future environmental protection industry development. The status quo of patent applications related to wastewater treatment technology was analyzed from the perspectives of application volume, disclosure volume, application organization, type composition of invention and utility model patent products and legal status. The results indicated that the total number of filed patents were 894, and the number of issued patents were 914 in recent ten years, showing an increasing trend for sewage treatment technology in Dalian, China. However, there were distinct differences between the application agencies of invention patents and utility model patents. Most of the invention patents came from universities, with 264 in the top five, and most of the utility model patents came from enterprises, with 134 in the top five. Among the product types, the highest number of patent applications was water, wastewater, or sludge treatment technology, a total of 761. At this point, the two patent directions had the same trend. In the state of law, although the number of applications and disclosures was 470, which was more than 416 actually authorized, it was not difficult to find that sewage treatment industry in Dalian, China was in an increasingly developing stage and the patents actually obtained had higher quality assurance. In conclusion, this essay from the perspective of patent application made a simple explanation the future development of sewage treatment industry and the problems existing in the practical application of sewage treatment technology. Finally, from the perspective of patent application, the paper analyzed the future development of sewage treatment industry and the problems existing in the practical application of sewage treatment technology.

Abstract We have previously reported the purification of a 37-kd platelet- agglutinating protein (PAP p37) from the plasma of a patient with thrombotic thrombocytopenic purpura (TTP) that was shown to be present in a subset of TTP patients. The platelet agglutination induced by PAP p37 has been shown to be inhibited by IgG from normal human adults and the same TTP patient after recovery. To elucidate the mechanism of inhibition of IgG, the interaction between PAP p37 and IgG was studied. The complex formation was demonstrated by the binding of fluid-phase IgG from normal adults and the same TTP patient after recovery to adsorbed PAP by using an enzyme-linked immunosorbent assay. The binding was specific, concentration dependent, and saturable. IgG purified from a 5-month-old baby and the same TTP patient during active disease did not form complex with PAP p37. The IgG covalently cross-linked to Sepharose 4B bound 125I-PAP p37 but not 125I-fibrinogen. Sucrose density gradient ultracentrifugation of a mixture of 125I-PAP p37 and IgG also revealed the fluid-phase complex formation with a sedimentation value of 19S. Complexes of molecular weight ranging from 180,000 to over 350,000 daltons were also detected by molecular sieve chromatography. The IgG that was bound to PAP p37 conjugated to Sepharose 4B inhibited the agglutination of washed platelets induced by TTP plasma containing PAP p37, whereas the IgG that was not bound to PAP p37 did not have a significant inhibitory effect. The complex formation between PAP p37 and specific IgG is likely to account for the in vitro inhibition of TTP plasma-induced agglutination and, at least partly, the in vivo successful treatment with specific IgG-containing normal plasma.

We have previously reported the purification of a 37-kd platelet- agglutinating protein (PAP p37) from the plasma of a patient with thrombotic thrombocytopenic purpura (TTP) that was shown to be present in a subset of TTP patients. The platelet agglutination induced by PAP p37 has been shown to be inhibited by IgG from normal human adults and the same TTP patient after recovery. To elucidate the mechanism of inhibition of IgG, the interaction between PAP p37 and IgG was studied. The complex formation was demonstrated by the binding of fluid-phase IgG from normal adults and the same TTP patient after recovery to adsorbed PAP by using an enzyme-linked immunosorbent assay. The binding was specific, concentration dependent, and saturable. IgG purified from a 5-month-old baby and the same TTP patient during active disease did not form complex with PAP p37. The IgG covalently cross-linked to Sepharose 4B bound 125I-PAP p37 but not 125I-fibrinogen. Sucrose density gradient ultracentrifugation of a mixture of 125I-PAP p37 and IgG also revealed the fluid-phase complex formation with a sedimentation value of 19S. Complexes of molecular weight ranging from 180,000 to over 350,000 daltons were also detected by molecular sieve chromatography. The IgG that was bound to PAP p37 conjugated to Sepharose 4B inhibited the agglutination of washed platelets induced by TTP plasma containing PAP p37, whereas the IgG that was not bound to PAP p37 did not have a significant inhibitory effect. The complex formation between PAP p37 and specific IgG is likely to account for the in vitro inhibition of TTP plasma-induced agglutination and, at least partly, the in vivo successful treatment with specific IgG-containing normal plasma.

Surface Enhanced Laser Desorption/Ionization Time Of Flight (SELDI-TOF) mass spectrometry is characterized by integration of mass spectrometry with surface chemistry, which gives rise to rapid purification and subsequent determination of protein/peptide analytes. There are several surface matrices, named proteinChips, available for analyzing a particular analyte or a subset of biomolecules in biological samples. Each proteinChip has a unique surface property suitable for fractionation of a specific group of molecules. This article demonstrates the application of SELDI-TOF for the analysis of a cleaved peptide (Mr7739 daltons) from von Willebrand Factor by a metalloproteinase, ADAMTS13. Deficiency of ADAMTS13 is a known primary risk factor for the devastating hematological disorder, Thrombotic thrombocytopenic purpura (TTP). Rapid determination of ADAMTS13 activity helps clinicians tremendously in making the correct diagnosis and initiating timely therapy. Most patients with TTP are acquired cases who exhibit a production of autoimmune antibodies against ADAMTS13 protease. TTP's clinical course is critically controlled by the autoantibody's ability to inhibit ADAMTS13 function. Thus, a second SELDI-TOF based test has been devised to measure ADAMTS13 autoantibody activity for the evaluation of TTP disease activity. In conclusion, the unique features of SELDI-TOF which allow for the examination of the role of key proteases in disease processes have opened up new doors for the clinical application of mass spectrometer based techniques.

Abstract We produced two hybridomas by fusion of mouse myeloma cells with splenocytes from a mouse immunized with the THP-1 human monocytoid leukemia cell line. Two cloned hybridoma cell lines, designated as TM2 and TM3, were obtained. They secreted antibodies against a unique cell surface antigen expressed on all normal peripheral blood monocytes, neutrophilic granulocytes, platelets, and mitogen-induced lymphoblasts, some cells from patients with immature-type lymphoid leukemias. However, the antibodies reacted neither with large numbers of peripheral blood lymphocytes nor with red cells. Cross-blocking studies showed that these monoclonal antibodies recognized the same or a nearly positioned antigen epitope. Immunoprecipitation of THP-1 cell extract with TM2 or TM3 under reducing and nonreducing conditions yielded a specific band of mol wt equal to 120,000 daltons. This determinant appeared to be involved in granulocyte chemotaxis, since neutrophilic granulocytes exposed to TM2 or TM3 showed a significant decrease in chemotaxis toward endotoxin-activated serum. These two monoclonal antibodies did not affect O2- release or luminol-dependent chemiluminescence of neutrophils. Moreover, they did not alter platelet aggregation induced by thrombin. TM2 and TM3 will provide a new reagent in defining the linkage between lymphoid and myeloid differentiation and intermyeloid development.

We produced two hybridomas by fusion of mouse myeloma cells with splenocytes from a mouse immunized with the THP-1 human monocytoid leukemia cell line. Two cloned hybridoma cell lines, designated as TM2 and TM3, were obtained. They secreted antibodies against a unique cell surface antigen expressed on all normal peripheral blood monocytes, neutrophilic granulocytes, platelets, and mitogen-induced lymphoblasts, some cells from patients with immature-type lymphoid leukemias. However, the antibodies reacted neither with large numbers of peripheral blood lymphocytes nor with red cells. Cross-blocking studies showed that these monoclonal antibodies recognized the same or a nearly positioned antigen epitope. Immunoprecipitation of THP-1 cell extract with TM2 or TM3 under reducing and nonreducing conditions yielded a specific band of mol wt equal to 120,000 daltons. This determinant appeared to be involved in granulocyte chemotaxis, since neutrophilic granulocytes exposed to TM2 or TM3 showed a significant decrease in chemotaxis toward endotoxin-activated serum. These two monoclonal antibodies did not affect O2- release or luminol-dependent chemiluminescence of neutrophils. Moreover, they did not alter platelet aggregation induced by thrombin. TM2 and TM3 will provide a new reagent in defining the linkage between lymphoid and myeloid differentiation and intermyeloid development.

Aqueous phase separation (APS) is a recently developed sustainable alternative to the conventional organic solvent based nonsolvent-induced phase separation (NIPS) method to prepare polymeric membranes. In APS, polyelectrolytes are precipitated from aqueous solutions through pH or salinity switches. Although APS differs from NIPS in the polymer and solvents, they share many tuning parameters. In this work, we investigate the APS-based preparation of membranes from poly(styrene-alt-maleic acid) (PSaMA) with a focus on acid concentration in the coagulation bath, and polymer and additive concentration in the casting solution. Nanofiltration membranes are prepared using significantly lower concentrations of acid: 0.3 M HCl compared to the 2 M of either acetic or phosphoric acid used in previous works. It is shown that higher polymer concentrations can be used to prevent defect formation in the top layer. In addition, acetic acid concentration also strongly affects casting solution viscosity and thus can be used to control membrane structure, where lower acetic acid concentrations can prevent the formation of macrovoids in the support structure. The prepared nanofiltration membranes exhibit a very low molecular weight cutoff (210 ± 40 dalton), making these sustainable membranes very relevant for the removal of contaminants of emerging concern. Understanding how the parameters described here affect membrane preparation and performance is essential to optimizing membranes prepared with APS towards this important application.

Bacille Calmette-Guerin (BCG) still the only authenticated vaccine against tuberculosis. Due to its drawbacks, a need for a new formula has emerged. The implication of “Nanovaccinology” is one of the possible alternatives. The non-viral vectors have a low transfection ability. In the context, this work aims to add two adjuvants to a calcium phosphate nanoparticles (CPNPs) functionalized with early secreted antigenic target 6-kilo dalton ( ESAT-6) cloned pcDNA3.1(+) plasmid. ESAT-6 gene is specific to mycobacterium tuberculosis complex (MTC) and encodes a T-cell antigen. The adjuvants in practice are Herring protamine and cytosine-phosphodiester bond-guanosine-oligodeoxynucleotide 7909 ( CpG-ODN 7909). Each has a different strategy in enhancing immune response; protamine is particulate adjuvant while CpG is an immunopotentiator substance. Nano complex was transfected into THP-1 monocytic cell line after its activation to a macrophage via 100nM PMA. Cellular immune response, interleukin-12 (IL-12), and tumor necrosis factor –alfa (TNF-ɑ) also ESAT-6 protein production were assayed via the Sandwich ELISA technique. Results revealed that CPNPs offer only partial protection to the adsorbed plasmid against enzymatic degradation. Nano complex formula with two adjuvants resulted in significantly higher cellular immune response comparing to formula carrying one adjuvant. In conclusion, the implication of CPNPs in gene delivery accompanied with two adjuvants each possess different strategy, will result in partial protection to the delivered gene with upsurge cellular immune response.

More and more irregular structure appears in people's lives, while the theoretical research and disaster experience show that the irregular structure in the earthquake will produce translation and torsion coupled spatial vibration, and sometimes it will cause very serious consequences. Being based on the practical engineering -the Castle Hotel of Dalian, this text makes use of finite element analysis software--- ANSYS. By analyzing the dynamic characteristics and seismic response, we get the self-vibration characteristics of the structure and the time history curve of top level displacement and acceleration of the structure under the effect of earthquake forces. The calculation results indicate that it is effective and reasonable to set up three-dimensional finite element model used for the analyzing of seismic response by ANSYS.

City sustainability is an important issue in the urbanization process. In this paper, the sustainability of 14 cities in Liaoning province in China is evaluated and predicted. The process of evaluating city sustainability is viewed as a multi-criteria decision-making problem. A simple additive weighting method is used for aggregating the normalized sustainability criteria data, built based on the three-pillar model and the associated weights. The results indicate that although the sustainability of the cities in Liaoning province is not perfect, the cities show better development momentum. For example, only two cities’ (Shenyang and Dalian) average performance scores in 2010–2016 were over 0.5, but all the cities’ sustainability improved in 2016 compared to 2010. We develop a stochastic simulation procedure used for predicting a city’s sustainability in future years. Many prediction results were obtained, including the maximum, minimum, and average performance scores of the cities, the pairwise priority matrix representing the ratio of one city outperforming another, and the ranking of cities’ sustainability with probabilities. The prediction results indicate various degrees of increase for almost all the cities’ sustainability in the future, which is consistent with the judgment of better development momentum determined from the evaluation results. Moreover, the cities of Dandong, Panjin may exceed Shenyang, Dalian, and rank in the top among all the cities in future years.

Abstract The Lushun-Dalian area of the South Liaodong Peninsula, in NE China, located in the SE margin of the North China Craton (NCC) exposes a suite of Middle-Late Proterozoic low-grade metamorphic sedimentary rocks which can be divided into a lower competent layer, a middle incompetent layer, and an upper competent layer on the basis of lithology and deformation style. Two stages of deformation recorded both in the metasedimentary rocks and a magmatic complex intruded in them indicate that the Lushun-Dalian area is a key region to decipher the Triassic–Jurassic tectonic evolution of the eastern NCC. The earliest D1 deformation mylonitized the magmatic complex and thrusted it northeastward over the low-grade metasedimentary rocks, in which a series of NE-verging folds and NE-directed brittle thrust faults developed. The D2 deformation erased the D1 fabrics in the incompetent layer by a top-to-the-NW ductile shearing and refolded the D1 fabrics in the lower and upper competent units, producing a series of km-scale SW-plunging folds. New zircon secondary ion mass spectrometry and laser ablation–inductively coupled plasma–mass spectrometry U-Pb ages from the magmatic complex and the granite porphyry dikes intruded in it, combined with the unconformity between the low-grade metasedimentary rocks and the Early Cretaceous volcanic rocks, indicate that D1 and D2 occurred after 211 Ma and before the Early Cretaceous. The decrease of the deformation intensity of D1 and D2 from the Lushun-Dalian area toward the interior of the NCC in the NE and NW directions suggests that D1 was the structural response in the overriding plate to the NCC-South China Block convergence during the Late Triassic to Early Jurassic, and D2 was the structural response to the northwestward subduction of the Paleo–Pacific plate beneath the NCC in the Middle-Late Jurassic. The superimposition of D2 on D1 recorded a significant tectonic transformation from the nearly E-W–trending Tethysian domain to the NE-SW–trending Pacific domain.

Sugar beet (Beta vulgaris L.) plants exhibiting dull green and chlorotic foliage were first observed in a field near Dalton, NE, in late July 1999. Root symptoms included distal tip rot with internal, yellow-brown, water-soaked tissues. Isolations on MBV medium (1) consistently yielded Aphanomyces cochlioides Drechs. Water cultures produced primary zoospores that encysted at the tips of sporangiophores, followed by release of secondary zoospores within 12 h. Seedlings inoculated with zoospores began to die 2 weeks after emergence in a greenhouse. Symptoms on hypocotyls began as water-soaked lesions that turned black and thread-like. The causal agent was reisolated from infected seedlings, completing Koch's postulates. The disease was subsequently found in more than 15 separate fields, representing 5 of 11 sugar beet-growing counties in Nebraska and 1 county in Wyoming. In October, plants from the same fields were observed with stunted, distorted roots and superficial, scabby lesions associated with latent A. cochlioides infection. The pathogen could not be isolated from this stage but was confirmed by observing mature oospores within thin, stained sections under a microscope. The sections were additionally mixed with sterile potting soil and planted in the greenhouse with sugar beets. Several weeks after emergence, seedlings began to die, and the pathogen was reisolated. This represents the first report of Aphanomyces root rot and its spread in the Central High Plains. It also confirms that the described latent symptoms on sugar beet are caused by A. cochlioides. Reference: (1). W. F. Pfender et al. Plant Dis. 68:845, 1984.

Based on the problem of tunnel running through bridge pile foundation, a 3d numerical model is built by the finite element software MIDAS/GTS in order to research the internal force and the displacement of the pile and soil during the Construction process. The sedimentation value of the top of the pile is bigger than others. Because the bigger thrust about the Shield machine, the horizontal displacement of the pile is increasing at first and decreasing at last from a positive into a negative. Because of the loss of the soil, the soil beside the pile collapses and causes strong friction force. The surface sedimentation value which is near the central line of the tunnel is bigger than other place. This paper is of good reference roles in the similar underground engineering in Dalian.

We directly expressed human R-ras 23,000-dalton protein (p23) cDNA in Escherichia coli under the control of the trp promoter. GTP-dependent phosphorylation of a p23 threonine 85 substitution mutant was observed. This result is in direct analogy to the autokinase activity of H-ras and K-ras threonine 59 substitution mutants. Normal p23 protein was detected in the human fibrosarcoma cell line HT1080 by immunoprecipitation with rabbit antibodies raised against an E. coli-expressed R-ras fusion protein. The R-ras p23 protein was found to be 3H labeled in the presence of [9,10(n)-3H]palmitic acid and is associated with the P100 membrane fraction of HT1080 cells. These data suggest that human R-ras p23 has biochemical properties very similar to those of the p21 products of the H-, K-, and N-ras proto-oncogenes. We constructed an R-ras minigene and engineered the expression of normal and mutant alleles from the simian virus 40 early region promoter. Normal and mutant R-ras gene products were authenticated by transient expression in COS-7 cells and immunoprecipitation. The valine 38-substituted R-ras p23 displayed reduced electrophoretic mobility. R-ras p21-like proteins, made by eliminating the first 26 R-ras codons, displayed evident mobility differences between the pro form and mature form, along with a valine 12 substitution-dependent change in electrophoretic mobility. Rat-1 fibroblasts were transfected with normal and mutant R-ras alleles and normal and activated H-ras alleles. Unlike the human T24 bladder oncogene-encoded p21, mutant R-ras alleles do not cause monolayer focus formation or growth in soft agar of rat fibroblasts.

We directly expressed human R-ras 23,000-dalton protein (p23) cDNA in Escherichia coli under the control of the trp promoter. GTP-dependent phosphorylation of a p23 threonine 85 substitution mutant was observed. This result is in direct analogy to the autokinase activity of H-ras and K-ras threonine 59 substitution mutants. Normal p23 protein was detected in the human fibrosarcoma cell line HT1080 by immunoprecipitation with rabbit antibodies raised against an E. coli-expressed R-ras fusion protein. The R-ras p23 protein was found to be 3H labeled in the presence of [9,10(n)-3H]palmitic acid and is associated with the P100 membrane fraction of HT1080 cells. These data suggest that human R-ras p23 has biochemical properties very similar to those of the p21 products of the H-, K-, and N-ras proto-oncogenes. We constructed an R-ras minigene and engineered the expression of normal and mutant alleles from the simian virus 40 early region promoter. Normal and mutant R-ras gene products were authenticated by transient expression in COS-7 cells and immunoprecipitation. The valine 38-substituted R-ras p23 displayed reduced electrophoretic mobility. R-ras p21-like proteins, made by eliminating the first 26 R-ras codons, displayed evident mobility differences between the pro form and mature form, along with a valine 12 substitution-dependent change in electrophoretic mobility. Rat-1 fibroblasts were transfected with normal and mutant R-ras alleles and normal and activated H-ras alleles. Unlike the human T24 bladder oncogene-encoded p21, mutant R-ras alleles do not cause monolayer focus formation or growth in soft agar of rat fibroblasts.

As people age, the community gradually becomes the main place for their daily activities. In old residential communities in China, variations in behaviors and venue choices of older adults reflect gender differences. This study focuses on the behavioral gender differences in old residential communities and the characteristics of venue use under the influence of the unique policies and culture of China. Semistructured interviews, behavioral mapping, and photo recording were utilized for data collection. The results showed that gender differences were reflected in the variability of behaviors and venue use of older adults. These differences are due to people’s living habits and gender characteristics as well as the top–down development of feminism in China. This study highlights the important role played by policies and culture in behavioral differences and stresses that systematically environmental construction could be used as a balanced means to address gender differences in old residential communities. This study also suggests minimizing activities with a strong gender orientation, balancing the gender allocation of service staff for older adults, and emphasizing space flexibility and versatility could help achieve a gender-balanced community environment.

The NAD+ -specific glutamate dehydrogenase (NAD-GDH) of the filamentous fungus Neurospora crassa is a tetrameric enzyme, regulated by catabolite repression. The amino acid sequence of this enzyme had been published several years ago. With the object of investigating the molecular mechanism of catabolite repression, the nucleotide sequence of genomic clones containing the coding region, along with 5′- and 3′-flanking noncoding segments of the NAD-GDH transcription unit, was obtained. The gdh structural gene was shown to code for a polypeptide of 1047 residues, with a calculated molecular mass of 118 280 daltons. The coding sequence is interrupted by two short introns located close to the N- and C-terminal domains of the polypeptide. Consensus intron boundaries and internal splice sequences resemble closely those of other N. crassa genes. A comparison of the amino acid sequence deduced from the nucleotide sequence with the previously published sequence showed several discrepancies between the two. Nucleotide sequence corresponding to a gap in the amino acid sequence was located in the genomic clone. Genetic mapping by restriction fragment length polymorphism analysis localized the gdh gene close to the loci trp-1 and con-7 on the right arm of linkage group III.Key words: Neurospora, NAD-specifïc glutamate dehydrogenase, sequences, gene map.

At present, there are few relevant studies on the intensive sea use, and few scholars have provided qualitative and quantitative research examples on the interaction and interaction coupling relationship between intensive sea use and the marine economy. This study constructs comprehensive evaluation indicator systems using the Liaoning Coastal Economic Belt as the research object. The set pair analysis method is used to obtain comprehensive results, and the coupling coordination degree model is employed to carry out an in-depth analysis of the spatiotemporal characteristics of the interaction between intensive sea use and the marine economy. The results show the following. (1) The six cities in the Liaoning Coastal Economic Belt exhibited a fluctuating upward trend in the composite index for intensive sea use, but the intensive sea use level differed among the cities. The intensive sea use level of Huludao was the lowest among the six cities. (2) All cities in the Liaoning Coastal Economic Belt witnessed an upward trend in the marine economy development index, and the gaps between the cities gradually narrowed. The marine economy development index was ranked from top to bottom as follows: Jinzhou, Panjin, Dalian, Yingkou, Dandong, and Huludao. (3)The coupling coordination degree between intensive sea use and marine economy development was relatively stable in Dalian, Jinzhou, Yingkou, and Panjin, ranging approximately from 0.76 to 0.96, which indicates that the four cities witnessed good coordination between sea area utilization and marine economy development. The coupling coordination degree of Dandong and Huludao were relatively low, and Huludao consistently witnessed a low value.

Based on scheme of Dalian gulf cross-sea bridge, in this paper, a 3-dimensional FE model for Self-anchored cable-stayed suspension bridge is established with finite element program and pile-soil-structure interaction is simulated by use of the equivalent embed fixation model. Based on the FE model, model analysis is carried out and the effects of pile-soil-structure interaction on dynamic behavior of long-span self-anchored cable-stayed suspension bridge are specially studied. The seismic response analysis result considering that pile-soil-structure interaction was compared with that of without considering such interaction. The analysis result show that interaction reduced horizontal displacement in middle span of stiffening beam and top of tower, horizontal moment not only at bottom of tower, but also assistant piers. The research results provide some theoretical foundation to composite structure system.

This paper studies the applicability of vibro-replacement stone pile in combination of a port project in Dalian as well as heavy dynamic sounding and standard penetration test, studies the reinforcement effect of pile distance and feeding type on vibro-replacement stone and analyzes reinforcement effects of the side pile and the earth among piles. The results show: smaller pile distance will bring better pile compactness; for the vibro-replacement stone pile constructed in soft earth with undrained strength less than 20kPa with the conventional method, it is not easy to form compact pile; the reinforcement effect works only within 0.6m on the top; vibro-replacement stone pile with bottom feeding mode can form compact piles, but the pile has the interlayer which is not compact enough partially; the strength of the earth among piles fails to improve obviously before and after the stone pile is formed.

The Harbin–Dalian high-speed railway in northeastern China has a significant portion of track foundation built on seasonally frozen ground. Wide-spread frost heave was observed during the first winter of its operation and the heave occurred mainly in coarse fills that were considered not susceptible to frost heave. This paper first presents the field data of frost heave and frost depth observed along the railway. It then analyses alternative mechanisms that have been considered to have caused the observed frost heave. The three most likely mechanisms are poor quality control of fine content in the coarse fill, the top-down water supply mechanism, and the bottom-up water supply mechanism. The likelihoods of these mechanisms are analysed against observed field data, using a one-dimensional frost heave model. The results indicate that the most likely explanation for the unexpected frost heave is a combined action of different mechanisms.

In this experiment, 25 oil degrading bacteria strains were isolated from the beach near Dalian Bay. The top 4 high efficient oil-degrading bacteria（SQ、SY 、SW、SC） were selected to be studied. Using Physiological and biochemical identification, electron microscopy, and 16S rDNA sequence analysis, strain SQ was identified as Advenella kashmirensis，SY was identified as Achromobacter xylosoxidans, SW was identified as Acinetobacter venetianus，SC was identified as Alcaligenes xylosoxidans subsp.xylosoxidans. For the first time this experiment provided reference to application and degradation characteristics of Advenella kashmirensis in crude oil treatment. These four marine oil degrading bacteria were selected to form bacterial consortium. The most efficient mixed strains were constructed by using these four strains with proportional combination. The oil removal ratio of the optimal mixed strains increased to 70.33%, nearly 25% higher than the highest degradation rate of single bacterium, showing significant synergism in the bacterial consortium. Advenella kashmirensis enhanced oil degradation obviously, playing a crucial role in the bacterial consortium.

Based on scheme of Dalian gulf cross-sea bridge, in this paper, a 3-dimensional FE model for Self-anchored cable-stayed suspension bridge is established with finite element program and pile-soil-structure interaction is simulated by use of the equivalent embed fixation model. Based on the FE model, model analysis is carried out and the effects of pile-soil-structure interaction on dynamic behavior of long-span self-anchored cable-stayed suspension bridge are specially studied. The seismic response analysis result considering that pile-soil-structure interaction was compared with that of without considering such interaction. The analysis result show that interaction extend the nature period of structure, has the greatest impact to the first vibration mode; meanwhile, enlarged longitudinal displacement and moment of stiffening beam in middle of main span, longitudinal displacement on top of tower and axial force at bottom, but reduced the moment of tower at bottom. The research results provide some theoretical foundation to composite structure system.

This paper reviews results obtained by the research groups developing the low-energy high-current pulsed electron beam (LEHCPEB) in Dalian (China) and Metz (France) on the surface treatment of light alloys. The pulsed electron irradiation induces an ultra-fast thermal cycle at the surface combined with the formation of thermal stress and shock waves. As illustrated for Mg alloys and Ti, this results in deep subsurface hardening (over several 100 μm) which improves the wear resistance. The analysis of the top surface melted surface of light alloys also often witnesses evaporation and condensation of chemical species. This phenomenon can significantly modify the melt chemistry and was also suggested to lead to the development of specific solidification textures in the rapidly solidified layer. The potential use of the LEHCPEB technique for producing thermomechanical treatments under the so-called heating mode and, thus, modify the surface crystallographic texture, and enhance solid-state diffusion is also demonstrated in the case of the FeAl intermetallic compound.

In this study concentration techniques regularly used for viral detection, i.e. flat-bed ultrafiltration and Filterite cartridge filtration, were evaluated for their efficacies in the recovery of protozoan parasites from water. Recovery of cysts was studied using tap water seeded with Giardia muris cysts and compared to methods designed for the detection of protozoan parasites. Recovery of cysts utilizing 1.2µm membrane filters was 11.1% (4.5-23%) compared to 11.6% (2.7-25.5%) with ultrafiltration (pore size 46-50 Å, with a molecular cut off of 50 000 daltons). Comparison of these methods for the isolation of Giardia cysts and Cryptosporidium oocysts from environmental water samples also indicated a similar efficacy. The recovery of cysts from 1001 of seeded samples using a Cuno wynd cartridge filter was 12.2% (1.6-46%) compared to 13.4% (5-24.2%) using a Filterite cartridge filter. Although the results indicated similar recovery efficacies for these two methods, use of Filterite resulted in a more consistent recovery rate. This study also indicated that the use of cartridge filters for the processing of large volume water samples (1001) showed a slightly better recovery efficacy than the flat-bed filtration technique which limits sample volume to about 101. This study shows that concentration techniques utilised for the isolation of enteric viruses can also be applied for the detection of protozoan parasites from water. This procedure allows for co-analysis of both viruses and protozoan parasites and provides a more rapid and cost-effective evaluation of water quality.

Base on the elastic-plastic analytical theory, an elastic-plastic time-history analysis of self-anchored cable-stayed suspension bridge, which engineering background is Dalian Gulf Cross-sea Bridge program, is performed by using general finite element software Midas/Civil. The material nonlinearity of structure is considered with reinforcement concrete fiber model, and distributed hinge type is adopted to simulate for plastic hinge. Compared with the results of an elastic time-history analysis, it is shown that for the structure into the elastic-plastic stage, because of the production of plastic hinge, the input seismic energy is dissipated partially, and the internal forces of structural elements are reduced. The bending moments and axial forces occur mainly in the main tower root. Furthermore, the rotation properties of the plastic hinge causes displacement increasing of certain parts of the structure, which assumes mainly the vertical displacement present on the top of main tower and the main beam. In conclusion, it is proposed that caging devices are set in the design.

AbstractThe lithological and biotic succession across the late Precambrian to early Cambrian interval is outlined for the Dalir and Valiabad successions of the Elburz Mountains of Iran. The Lower Dolomite Member contains an assemblage of phosphatic tubes and other poorly preserved remains. The succeeding Lower Shale Member bears macroscopic chuariamorphid algae. Early skeletal fossil diversity rises through the Middle Dolomite Member, with the successive appearance ofProtohertzina anabarica, Cambrotubulus decurvatusandAnabarites trisulcatus, culminating near the top of the dolomites with the appearance ofPurellasp.,Maikhanella multa, Tiksitheca licisand circothecids. This succession is compared with lower to upper parts of the Nemakit-Daldyn Formation of Siberia. The overlying Upper Shale Member bears phosphatic beds at its base with allathecids and an uncoiled pelagiellid (?Aldanellasp.) that suggest comparison with lower Tommotian strata and the Precambrian–Cambrian boundary phosphorite event of southern and central Asia. A rich assemblage of molluscs appears high in the Upper Shale Member, including theLatouchella korobkovigroup and thePelagiella lorenzigroup. The succession is broadly homotaxial with those from the Siberian Platform and Mongolia and those platforms bordering Gondwana (India, Kazakhstan, South China).

Sustainable supply chain management (SSCM) has been attracting extensive attention from both practitioners and scholars. The main objective of this paper is to visualize and conduct a systematic scientometric review on 9151 articles and reviews published from 2007 to 2021. Research techniques of co-author analysis, co-word analysis, and co-citation analysis are applied to reveal the social structure, conceptual structure, and intellectual structure of the SSCM field, identify main concepts and research hotspots, and illuminate major specialties and emerging trends. The results of this work show that: (1) the top five most productive scholars are Joseph Sarkis, Kannan Govindan, Minglang Tseng, Angappa Gunasekaran, and Charbel Jose Chiappetta Jabbour. The top five most productive institutions are Hong Kong Polytech University, Islamic Azad University, University of Southern Denmark, Dalian University of Technology, and University of Tehran. (2) The main concepts include sustainable supply chain management, green supply chain management, circular economy, corporate social responsibility, and reverse logistics. The research hotspots of the SSCM field, currently, are game theory and circular economy related topics. (3) The leading researchers and influential journals are also identified. The emerging trends include sustainable supplier selection, circular economy, cap-and-trade regulation, blockchain technology, big data analytics, the COVID-19 pandemic, and the best-worst method and logistics performance. Finally, limitations and future researches are discussed. We expect this paper will show a big picture of the SSCM field for researchers as well as practitioners.

The lowest Cambrian of Avalon, or Placentian Series, is a relatively thick sequence (1,400 m) in southeastern Newfoundland. A newly proposed body fossil zonation supplements an existing trace fossil zonation of the lower part of the Placentian Series and includes strata to the top of the sub-trilobitic Lower Cambrian.The Sabellidites cambriensis Zone brackets the Precambrian–Cambrian boundary and comprises peritidal and wave-influenced subtidal facies deposited during deepening through the lower part of the Chapel Island Formation. Younger “Ladatheca” cylindrica Zone strata include the deepest facies of the Chapel Island Formation. The base of the overlying Watsonella crosbyi Zone (a post-Nemakit Daldyn and pre-Tommotian equivalent) is significantly diachronous because the diagnostic mollusks were preferentially preserved in pyritiferous offshore muds rather than in coeval nearshore muds. High diversity, upper Watsonella crosbyi Zone faunas (18 species) are limited to peritidal limestones of member 4 and are dominated by calcareous small shelly fossils. A thick interval (ca. 430 m) without body fossils and an important episode of block faulting that led to 750 m of differential erosion preceded deposition of the lower part of the Bonavista Group (=Sunnaginia imbricata Zone, an interval considered to be largely older than the Tommotian). Although much Early Cambrian time may be lost as a result of erosion at Random Formation–Bonavista Group unconformities, many Watsonella crosbyi Zone species reappear in the Sunnaginia imbricata Zone. Shoaling accompanied the immigration event defining the base of the Camenella baltica Zone, and an unconformity following regional offlap marks the top of the Placentian Series.Calcareous, and not phosphatic, composition is most common in earliest Cambrian shelly remains. Little evidence suggests that a global, Precambrian–Cambrian boundary interval “phosphogenic” event either resulted in deposition of local phosphate deposits in the Tethyan region or had a role in the appearance of mineralized skeletons.Twenty metazoans and problematica and an alga are illustrated from the Chapel Island Formation. Bemella? vonbitteri Landing n. sp. and Halkieria stonei Landing n. sp. are described. The monoplacophoran Archaeospira? avalonensis Landing n. sp. has right-and left-handed conchs comparable to those of Archaeospira (=Yangtzespira) from China. Anabarites is the senior generic synonym of Tiksitheca.

Abstract. Infrastructure built on perennially frozen ice-rich ground relies heavily on thermally stable subsurface conditions. Climate-warming-induced deepening of ground thaw puts such infrastructure at risk of failure. For better assessing the risk of large-scale future damage to Arctic infrastructure, improved strategies for model-based approaches are urgently needed. We used the laterally coupled 1D heat conduction model CryoGrid3 to simulate permafrost degradation affected by linear infrastructure. We present a case study of a gravel road built on continuous permafrost (Dalton highway, Alaska) and forced our model under historical and strong future warming conditions (following the RCP8.5 scenario). As expected, the presence of a gravel road in the model leads to higher net heat flux entering the ground compared to a reference run without infrastructure and thus a higher rate of thaw. Further, our results suggest that road failure is likely a consequence of lateral destabilisation due to talik formation in the ground beside the road rather than a direct consequence of a top-down thawing and deepening of the active layer below the road centre. In line with previous studies, we identify enhanced snow accumulation and ponding (both a consequence of infrastructure presence) as key factors for increased soil temperatures and road degradation. Using differing horizontal model resolutions we show that it is possible to capture these key factors and their impact on thawing dynamics with a low number of lateral model units, underlining the potential of our model approach for use in pan-Arctic risk assessments. Our results suggest a general two-phase behaviour of permafrost degradation: an initial phase of slow and gradual thaw, followed by a strong increase in thawing rates after the exceedance of a critical ground warming. The timing of this transition and the magnitude of thaw rate acceleration differ strongly between undisturbed tundra and infrastructure-affected permafrost ground. Our model results suggest that current model-based approaches which do not explicitly take into account infrastructure in their designs are likely to strongly underestimate the timing of future Arctic infrastructure failure. By using a laterally coupled 1D model to simulate linear infrastructure, we infer results in line with outcomes from more complex 2D and 3D models, but our model's computational efficiency allows us to account for long-term climate change impacts on infrastructure from permafrost degradation. Our model simulations underline that it is crucial to consider climate warming when planning and constructing infrastructure on permafrost as a transition from a stable to a highly unstable state can well occur within the service lifetime (about 30 years) of such a construction. Such a transition can even be triggered in the coming decade by climate change for infrastructure built on high northern latitude continuous permafrost that displays cold and relatively stable conditions today.

Purpose Performed over a five-year time horizon, this paper aims to analyze the progression rates of technological innovation across 15 sub-provincial Chinese cities. The authors quantify and rate innovation performance, then rank the cities based on a purpose-built index designed to gauge the rate of technological progress. Design/methodology/approach Using the inferior constraint method, and a variety of national sources of data, the authors construct an innovation index based in part on new product sales revenue, proportion of college students, research and development expenditure of industrial enterprises in relation to gross industrial output value, contract deals in technical markets per capita, hazard-free treatment rate of waste, enterprises with technical development agencies accounts for industrial enterprises, number of high-tech enterprises and invention patent ownership per million population. Findings The findings provide a methodology for indexing cities, with 15 Chinese provincial cities as examples. Among the top five cities with the highest technological innovation index were Shenzhen, Nanjing, Guangzhou, Hangzhou and Wuhan. In the bottom were Shenyang, Changchun, Dalian, Xi’an and Harbin. Research limitations/implications This study applied a new model of innovation at the city level for China. Application to other industries (real estate, manufacturing, etc.) and countries will extend boundaries of this model and show its wider applicability. Practical implications Companies can use this research and methodology when seeking new investments in high tech and innovative products. Locations offering more hospitable environments should be prioritized ceteris paribus. Originality/value One weakness of much of the international business and competitiveness literature is that it often views the country as the primary unit of analysis. In this way, nuanced views of the institutional environments within countries are often overlooked. This paper proposes a measure of regional rates of innovativeness across China.

A Review of: Ramírez, M. L., McMillan, G., Dalton, J. T., Hanlon, A., Smith, H. S., & Kern, C. (2014). Do open access electronic theses and dissertations diminish publishing opportunities in the sciences? College & Research Libraries, 75(6), 808-821. http://dx.doi.org/10.5860/ crl.75.6.808 Abstract Objective – To assess science journal publishers’ attitudes and policies regarding open access electronic theses and dissertations (ETDs). Design – Survey questionnaire. Setting – Science journal publications. Subjects – Editorial team members from 290 high-impact science journals. Methods – The 16,455 science journals listed in the 2005-09 Thompson Reuter’s Journal Performance Indicators (JPI) were identified as the base population for this study. The top five journals, as ranked by relative impact factor, from each of the 171 JPI-defined science disciplines were selected for the sampling frame. After the removal of duplicates, defunct titles, and pretest participants, the 715 resulting journals were grouped into 14 broader subject groups defined by the researchers. Randomized systematic sample was then employed to select a final sample size of 300 journals. Ten additional titles were later removed due to publication scope. Email invitations to participate in the survey were sent to the selected journals on August 9, 2012. After two email reminders, the web survey closed on August 27. Six phone follow-ups were made to a random sample of 100 out of the 246 non-responders between September 7 and 14 to increase the response rate. Main Results – The final response rate for the survey was 24.8% (72 out of 290), and the findings had an 11.5% margin of error with 95% confidence interval. Only 12.5% of the journals surveyed indicated they would “never accept” manuscripts derived from open access ETDs, while 51.4% indicated revised EDTs are “always welcome.” The rest of the respondents had some acceptance restrictions, including case-by-case review (19.4%), accept only if the content differs significantly from the original (8.3%), accept or only if access to the original ETD was limited (1.4%). Five of the 72 respondents (6.9%) did not have a policy for accepting ETDs. Of the 17 researcher-created discipline categories, Engineering titles had the highest (85.7%, or 12 out of 14) and Medical journals had the lowest (25%, or 3 out of 14) proportion of respondents who would “always welcome” manuscripts derived from open access ETDs. At least 50% of the journals from every type of publishing entity indicated they would “always welcome” revised ETDs. However, there are differences between the entities: University Presses were most likely to “always welcome” revised ETDs (87.5%), Commercial Publishers were more likely to have some acceptance restrictions (41.7%), and Academic Societies were the most likely entity to “never welcome” revised ETDs (12.7%). Lastly, in a comparison of the results of this study with the results from a similar 2013 study conducted on social science, arts and humanities (SS&H) journals, the authors found statistically significant differences (p=0.025, α=0.05) between the editorial policies regarding revised ETDs of science and SS&H journals. Conclusion – The study results suggest that, contrary to common perceptions, the majority of high-impact science journals would actually welcome revised open access ETDs submissions. Therefore, science scholars would not greatly reduce their chances for publishing manuscripts derived from EDTs by making the original ETDs accessible online.

Xanthium orientale subsp. italicum (Moretti) Greuter is an annual herbaceous plant in the Asteraceae family, native to North America. It was first found in Beijing, China, in 1991. Since then, it has spread into many provinces such as Heilongjiang, Jilin, Liaoning, Hebei, Shandong, Xinjiang, and so on. Furthermore, it has been listed as one of the dangerous quarantine weeds in China (4). This noxious invasive weed has a strong ability to acclimatize to new environments. X. orientale subsp. italicum can usually be found in alluvial flatlands, riverbanks, wastelands, roadsides, pastures, as well as farmlands. The presence of this plant decreases the native biodiversity and influences the production of agriculture and stockbreeding. In August 2013, a rust disease was first observed on X. orientale subsp. italicum in Dalian, Liaoning Province, northeast China. Various sized lesions were found on approximately one third of the leaves of each infected plant. These lesions were yellow in the early stage of infection; gradually the center of each lesion turned brown, and eventually the infected lesions became necrotic and ruptured. The small (on average 4 mm in diameter) and dark brown raised telia appeared in the center of the lesions on the lower leaf surface. The teliospores were brown, clavate, two-celled, and measured 42 to 58 × 12 to 21 μm. Teliospores had a conical top, constricted septa, and a persistent pedicel (22 to 70 μm in length). The walls of the teliospores were smooth, 0.8 to 1.2 μm thick at the side and 4 to 8 μm thick at the apex. The size, color, and morphology of the teliospores fit the description of Puccinia xanthii (1,3). A pathogenicity test was conducted by the method of detached leaf inoculation (2). We collected 48 healthy leaves from six individuals of X. orientale subsp. italicum plants, eight from each individual. Teliospores from disease samples were suspended to 1 × 105 spores per ml with sterile water and then smeared on 24 leaves (four per individual); the remaining leaves were inoculated with sterile water as control. Each of the leaves was put on a moist filter paper in a petri dish, and was cultured in a chamber with a 12-h photoperiod at 25°C. Seven days later, dark brown raised telia were observed on all inoculated leaves but not on control ones. The teliospores were removed from the sorus on inoculated leaves, and according to the morphology confirmed to be those of P. xanthii. The rust caused by P. xanthii has been documented in different hosts in many other countries such as Spain, France, Italy, former Yugoslavia, Australia, the United States, and South Africa. In addition, the rust fungus was found to infect X. orientale subsp. italicum in eastern Hungary (1). To our knowledge, this is the first report of P. xanthii attacking the invasive plant X. orientale subsp. italicum in China. It is important to study the potential of using this rust fungus as a biological control agent of X. orientale subsp. italicum. This work was supported by the Project of the National Natural Science Foundation of China (31270582). References: (1) I. Dávid et al. Plant Dis. 87:1536, 2003. (2) Z. D. Fang. Research Methods of Plant Disease, 1998. (3) J. A. Parmelee. Can. J. Bot. 47:1391, 1969. (4) F. H. Wan et al. Biological Invasion: Color Illustration of Invasive Alien Plants in China, 2012.

<p><strong>List of abstracts and authors:</strong></p><p><strong>1. Antipsychotics in anxiety disorders</strong></p><p>Christer Allgulander</p><p><strong>2. Anxiety in somatic disorders</strong></p><p>Christer Allgulander</p><p><strong>3. Community rehabilitation of the schizophrenic patient</strong></p><p>Orlando Alonso Betancourt, Maricela Morales Herrera</p><p><strong>4. Dual diagnosis: A theory-driven multidisciplinary approach for integrative care</strong></p><p>David Blackbeard</p><p><strong>5. The emotional language of the gut - when 'psyche' meets 'soma'</strong></p><p>Helen Clark</p><p><strong>6. The Psychotherapy of bipolar disorder</strong></p><p>Franco Colin</p><p><strong>7. The Psychotherapy of bipolar disorder</strong></p><p>Franco Colin</p><p><strong>8. Developing and adopting mental health policies and plans in Africa: Lessons from South Africa, Uganda and Zambia</strong></p><p>Sara Cooper, Sharon Kleintjes, Cynthia Isaacs, Fred Kigozi, Sheila Ndyanabangi, Augustus Kapungwe, John Mayeya, Michelle Funk, Natalie Drew, Crick Lund</p><p><strong>9. The importance of relapse prevention in schizophrenia</strong></p><p>Robin Emsley</p><p><strong>10. Mental Health care act: Fact or fiction?</strong></p><p>Helmut Erlacher, M Nagdee</p><p><strong>11. Does a dedicated 72-hour observation facility in a district hospital reduce the need for involuntary admissions to a psychiatric hospital?</strong></p><p>Lennart Eriksson</p><p><strong>12. The incidence and risk factors for dementia in the Ibadan study of ageing</strong></p><p>Oye Gureje, Lola Kola, Adesola Ogunniyi, Taiwo Abiona</p><p><strong>13. Is depression a disease of inflammation?</strong></p><p><strong></strong>Angelos Halaris</p><p><strong>14. Paediatric bipolar disorder: More heat than light?</strong></p><p>Sue Hawkridge</p><p><strong>15. EBM: Anova Conundrum</strong></p><p>Elizabeth L (Hoepie) Howell</p><p><strong>16. Tracking the legal status of a cohort of inpatients on discharge from a 72-hour assessment unit</strong></p><p>Bernard Janse van Rensburg</p><p><strong>17. Dual diagnosis units in psychiatric facilities: Opportunities and challenges</strong></p><p>Yasmien Jeenah</p><p><strong>18. Alcohol-induced psychotic disorder: A comparative study on the clinical characteristics of patients with alcohol dependence and schizophrenia</strong></p><p>Gerhard Jordaan, D G Nel, R Hewlett, R Emsley</p><p><strong>19. Anxiety disorders: the first evidence for a role in preventive psychiatry</strong></p><p>Andre F Joubert</p><p><strong>20. The end of risk assessment and the beginning of start</strong></p><p>Sean Kaliski</p><p><strong>21. Psychiatric disorders abd psychosocial correlates of high HIV risk sexual behaviour in war-effected Eatern Uganda</strong></p><p>E Kinyada, H A Weiss, M Mungherera, P Onyango Mangen, E Ngabirano, R Kajungu, J Kagugube, W Muhwezi, J Muron, V Patel</p><p><strong>22. One year of Forensic Psychiatric assessment in the Northern Cape: A comparison with an established assessment service in the Eastern Cape</strong></p><p>N K Kirimi, C Visser</p><p><strong>23. Mental Health service user priorities for service delivery in South Africa</strong></p><p>Sharon Kleintjes, Crick Lund, Leslie Swartz, Alan Flisher and MHaPP Research Programme Consortium</p><p><strong>24. The nature and extent of over-the-counter and prescription drug abuse in cape town</strong></p><p>Liezl Kramer</p><p><strong>25. Physical health issues in long-term psychiatric inpatients: An audit of nursing statistics and clinical files at Weskoppies Hospital</strong></p><p>Christa Kruger</p><p><strong>26. Suicide risk in Schizophrenia - 20 Years later, a cohort study</strong></p><p>Gian Lippi, Ean Smit, Joyce Jordaan, Louw Roos</p><p><strong>27.Developing mental health information systems in South Africa: Lessons from pilot projects in Northern Cape and KwaZulu-Natal</strong></p><p>Crick Lund, S Skeen, N Mapena, C Isaacs, T Mirozev and the Mental Health and Poverty Research Programme Consortium Institution</p><p><strong>28. Mental health aspects of South African emigration</strong></p><p>Maria Marchetti-Mercer</p><p><strong>29. What services SADAG can offer your patients</strong></p><p>Elizabeth Matare</p><p><strong>30. Culture and language in psychiatry</strong></p><p>Dan Mkize</p><p><strong>31. Latest psychotic episode</strong></p><p>Povl Munk-Jorgensen</p><p><strong>32. The Forensic profile of female offenders</strong></p><p>Mo Nagdee, Helmut Fletcher</p><p><strong>33. The intra-personal emotional impact of practising psychiatry</strong></p><p>Margaret Nair</p><p><strong>34. Highly sensitive persons (HSPs) and implications for treatment</strong></p><p>Margaret Nair</p><p><strong>35. Task shifting in mental health - The Kenyan experience</strong></p><p>David M Ndetei</p><p><strong>36. Bridging the gap between traditional healers and mental health in todya's modern psychiatry</strong></p><p>David M Ndetei</p><p><strong>37. Integrating to achieve modern psychiatry</strong></p><p>David M Ndetei</p><p><strong>38. Non-medical prescribing: Outcomes from a pharmacist-led post-traumatic stress disorder clinic</strong></p><p>A Parkinson</p><p><strong>39. Is there a causal relationship between alcohol and HIV? Implications for policy, practice and future research</strong></p><p>Charles Parry</p><p><strong>40. Global mental health - A new global health discipline comes of age</strong></p><p>Vikram Patel</p><p><strong>41. Integrating mental health into primary health care: Lessons from pilot District demonstration sites in Uganda and South Africa</strong></p><p>Inge Petersen, Arvin Bhana, K Baillie and MhaPP Research Programme Consortium</p><p><strong>42. Personality disorders -The orphan child in axis I - Axis II Dichotomy</strong></p><p><strong></strong>Willie Pienaar</p><p><strong>43. Case Studies in Psychiatric Ethics</strong></p><p>Willie Pienaar</p><p><strong>44. Coronary artery disease and depression: Insights into pathogenesis and clinical implications</strong></p><p>Janus Pretorius</p><p><strong>45. Impact of the Mental Health Care Act No. 17 of 2002 on designated hospitals in KwaZulu-Natal: Triumphs and trials</strong></p><p>Suvira Ramlall, Jennifer Chipps</p><p><strong>46. Biological basis of addication</strong></p><p>Solomon Rataemane</p><p><strong>47. Genetics of Schizophrenia</strong></p><p>Louw Roos</p><p><strong>48. Management of delirium - Recent advances</strong></p><p>Shaquir Salduker</p><p><strong>49. Social neuroscience: Brain research on social issues</strong></p><p>Manfred Spitzer</p><p><strong>50. Experiments on the unconscious</strong></p><p>Manfred Spitzer</p><p><strong>51. The Psychology and neuroscience of music</strong></p><p>Manfred Spitzer</p><p><strong>52. Mental disorders in DSM-V</strong></p><p>Dan Stein</p><p><strong>53. Personality, trauma exposure, PTSD and depression in a cohort of SA Metro policemen: A longitudinal study</strong></p><p>Ugashvaree Subramaney</p><p><strong>54. Eating disorders: An African perspective</strong></p><p>Christopher Szabo</p><p><strong>55. An evaluation of the WHO African Regional strategy for mental health 2001-2010</strong></p><p>Thandi van Heyningen, M Majavu, C Lund</p><p><strong>56. A unitary model for the motor origin of bipolar mood disorders and schizophrenia</strong></p><p>Jacques J M van Hoof</p><p><strong>57. The origin of mentalisation and the treatment of personality disorders</strong></p><p>Jacques J M Hoof</p><p><strong>58. How to account practically for 'The Cause' in psychiatric diagnostic classification</strong></p><p>C W (Werdie) van Staden</p><p><strong>POSTER PRESENTATIONS</strong></p><p><strong>59. Problem drinking and physical and sexual abuse at WSU Faculty of Health Sciences, Mthatha, 2009</strong></p><p>Orlando Alonso Betancourt, Maricela Morales Herrera, E, N Kwizera, J L Bernal Munoz</p><p><strong>60. Prevalence of alcohol drinking problems and other substances at WSU Faculty of Health Sciences, Mthatha, 2009</strong></p><p>Orlando Alonso Betancourt, Maricela Morales Herrera, E, N Kwizera, J L Bernal Munoz</p><p><strong>61. Lessons learnt from a modified assertive community-based treatment programme in a developing country</strong></p><p>Ulla Botha, Liezl Koen, John Joska, Linda Hering, Piet Ooosthuizen</p><p><strong>62. Perceptions of psychologists regarding the use of religion and spirituality in therapy</strong></p><p>Ottilia Brown, Diane Elkonin</p><p><strong>63. Resilience in families where a member is living with schizophreni</strong></p><p>Ottilia Brown, Jason Haddad, Greg Howcroft</p><p><strong>64. Fusion and grandiosity - The mastersonian approach to the narcissistic disorder of the self</strong></p><p>William Griffiths, D Macklin, Loray Daws</p><p><strong>65. Not being allowed to exist - The mastersonian approach to the Schizoid disorder of the self</strong></p><p>William Griffiths, D Macklin, Loray Daws</p><p><strong>66. Risky drug-injecting behaviours in Cape Town and the need for a needle exchange programme</strong></p><p>Volker Hitzeroth</p><p><strong>67. Neuroleptic malignant syndrome in adolescents in the Western Cape: A case series</strong></p><p>Terri Henderson</p><p><strong>68. Experience and view of local academic psychiatrists on the role of spirituality in South African specialist psychiatry, compared with a qualitative analysis of the medical literature</strong></p><p>Bernard Janse van Rensburg</p><p><strong>69. The role of defined spirituality in local specialist psychiatric practice and training: A model and operational guidelines for South African clinical care scenarios</strong></p><p>Bernard Janse van Rensburg</p><p><strong>70. Handedness in schizophrenia and schizoaffective disorder in an Afrikaner founder population</strong></p><p>Marinda Joubert, J L Roos, J Jordaan</p><p><strong>71. A role for structural equation modelling in subtyping schizophrenia in an African population</strong></p><p>Liezl Koen, Dana Niehaus, Esme Jordaan, Robin Emsley</p><p><strong>72. Caregivers of disabled elderly persons in Nigeria</strong></p><p>Lola Kola, Oye Gureje, Adesola Ogunniyi, Dapo Olley</p><p><strong>73. HIV Seropositivity in recently admitted and long-term psychiatric inpatients: Prevalence and diagnostic profile</strong></p><p>Christina Kruger, M P Henning, L Fletcher</p><p><strong>74. Syphilis seropisitivity in recently admitted longterm psychiatry inpatients: Prevalence and diagnostic profile</strong></p><p>Christina Kruger, M P Henning, L Fletcher</p><p><strong>75. 'The Great Suppression'</strong></p><p>Sarah Lamont, Joel Shapiro, Thandi Groves, Lindsey Bowes</p><p><strong>76. Not being allowed to grow up - The Mastersonian approach to the borderline personality</strong></p><p>Daleen Macklin, W Griffiths</p><p><strong>77. Exploring the internal confirguration of the cycloid personality: A Rorschach comprehensive system study</strong></p><p>Daleen Macklin, Loray Daws, M Aronstam</p><p><strong>78. A survey to determine the level of HIV related knowledge among adult psychiatric patients admitted to Weskoppies Hospital</strong></p><p><strong></strong> T G Magagula, M M Mamabolo, C Kruger, L Fletcher</p><p><strong>79. A survey of risk behaviour for contracting HIV among adult psychiatric patients admitted to Weskoppies Hospital</strong></p><p>M M Mamabolo, T G Magagula, C Kruger, L Fletcher</p><p><strong>80. A retrospective review of state sector outpatients (Tara Hospital) prescribed Olanzapine: Adherence to metabolic and cardiovascular screening and monitoring guidelines</strong></p><p>Carina Marsay, C P Szabo</p><p><strong>81. Reported rapes at a hospital rape centre: Demographic and clinical profiles</strong></p><p>Lindi Martin, Kees Lammers, Donavan Andrews, Soraya Seedat</p><p><strong>82. Exit examination in Final-Year medical students: Measurement validity of oral examinations in psychiatry</strong></p><p>Mpogisheng Mashile, D J H Niehaus, L Koen, E Jordaan</p><p><strong>83. Trends of suicide in the Transkei region of South Africa</strong></p><p>Banwari Meel</p><p><strong>84. Functional neuro-imaging in survivors of torture</strong></p><p>Thriya Ramasar, U Subramaney, M D T H W Vangu, N S Perumal</p><p><strong>85. Newly diagnosed HIV+ in South Africa: Do men and women enroll in care?</strong></p><p>Dinesh Singh, S Hoffman, E A Kelvin, K Blanchard, N Lince, J E Mantell, G Ramjee, T M Exner</p><p><strong>86. Diagnostic utitlity of the International HIC Dementia scale for Asymptomatic HIV-Associated neurocognitive impairment and HIV-Associated neurocognitive disorder in South Africa</strong></p><p>Dinesh Singh, K Goodkin, D J Hardy, E Lopez, G Morales</p><p><strong>87. The Psychological sequelae of first trimester termination of pregnancy (TOP): The impact of resilience</strong></p><p>Ugashvaree Subramaney</p><p><strong>88. Drugs and other therapies under investigation for PTSD: An international database</strong></p><p>Sharain Suliman, Soraya Seedat</p><p><strong>89. Frequency and correlates of HIV Testing in patients with severe mental illness</strong></p><p>Hendrik Temmingh, Leanne Parasram, John Joska, Tania Timmermans, Pete Milligan, Helen van der Plas, Henk Temmingh</p><p><strong>90. A proposed mental health service and personnel organogram for the Elizabeth Donkin psychiatric Hospital</strong></p><p>Stephan van Wyk, Zukiswa Zingela</p><p><strong>91. A brief report on the current state of mental health care services in the Eastern Cape</strong></p><p>Stephan van Wyk, Zukiswa Zingela, Kiran Sukeri, Heloise Uys, Mo Nagdee, Maricela Morales, Helmut Erlacher, Orlando Alonso</p><p><strong>92. An integrated mental health care service model for the Nelson Mandela Bay Metro</strong></p><p>Stephan van Wyk, Zukiswa Zingela, Kiran Sukeri</p><p><strong>93. Traditional and alternative healers: Prevalence of use in psychiatric patients</strong></p><p>Zukiswa Zingela, S van Wyk, W Esterhuysen, E Carr, L Gaauche</p>

The paper presents the interaction system within soil working mechanical process, consisting of two elements, namely the soil and the tool metal, between which there is a relative movement at the level of the interface between the two elements. Research has shown that there are at least two main forces acting on the active parts: friction and impact, the action of these forces causing wear. In order to test the soil working knives under laboratory conditions, a test stand was used to test different types of soil working knives by modifying their functional parameters, respectively the working depth, knife angle relative to the soil, lateral angle relative to the forward direction, working speed and, if necessary, granulation and moisture of the test medium respectively.

This study aims to investigate the feasibility of using nonwoven fabric material (NB) as bedding material in a circulating fluidized bed biofilter (FBB), coupling with a submerged membrane adsorption hybrid system (SMAHS) to treat high strength synthetic wastewater containing refractory organic pollutants. The results show that the NBFBB could remove major part of the organic pollutants at relatively low influent feeding rate of 10 and 20 mL/min with the bed depth of 25 cm and minimum recirculation rate of 50%. The integrated NB–FBB–SMAHS system exhibited excellent DOC and nutrient removal with the bed depth of 45 cm and 50% recirculation rate. At the NBFBB influent feeding rate of 50 mL/min, the system removed more than 96% of DOC, 100% of NH4–N and 84.2% PO4–P with a low TMP development of 9.5 kPa. Molecular weight (MW) distributions also indicated that the system could eliminate dissolved organic pollutants range from 90 to 40200 Daltons.

In this paper, numerical and experimental investigations are presented on the hydrodynamic performance of a horizontal tidal current turbine (TCT) designed and made by our Dalian University of Technology (DUT) research group. Thus, it is given the acronym: DUTTCT. An open-source computational fluid dynamics (CFD) solver, called pimpledymfoam, is employed to perform numerical simulations for design analysis, while experimental tests are conducted in a DUT towing tank. The important factors, including self-starting velocity, tip speed ratio (TSR), and yaw angle, which play important roles in the turbine output power, are studied in the investigations. Results obtained show that the maximum power efficiency of the newly developed turbine (DUTTCT) could reach up to 47.6%, and all its power efficiency is over 40% in the TSR range from 3.5 to 6; the self-starting velocity of DUTTCT is about 0.745 m/s; and the yaw angle has negligible influence on its efficiency as it is less than 10 deg.