Academic literature on the topic 'DBS'

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Journal articles on the topic "DBS"

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Vera, Miguel, Antonio Bravo, and Rubén Medina. "Description and Use of Three-Dimensional Numerical Phantoms of Cardiac Computed Tomography Images." Data 7, no. 8 (August 16, 2022): 115. http://dx.doi.org/10.3390/data7080115.

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The World Health Organization indicates the top cause of death is heart disease. These diseases can be detected using several imaging modalities, especially cardiac computed tomography (CT), whose images have imperfections associated with noise and certain artifacts. To minimize the impact of these imperfections on the quality of the CT images, several researchers have developed digital image processing techniques (DPIT) by which the quality is evaluated considering several metrics and databases (DB), both real and simulated. This article describes the processes that made it possible to generate and utilize six three-dimensional synthetic cardiac DBs or voxels-based numerical phantoms. An exhaustive analysis of the most relevant features of images of the left ventricle, belonging to a real CT DB of the human heart, was performed. These features are recreated in the synthetic DBs, generating a reference phantom or ground truth free of imperfections (DB1) and five phantoms, in which Poisson noise (DB2), stair-step artifact (DB3), streak artifact (DB4), both artifacts (DB5) and all imperfections (DB6) are incorporated. These DBs can be used to determine the performance of DPIT, aimed at decreasing the effect of these imperfections on the quality of cardiac images.
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Knani, Dafna, and David Alperstein. "Simulation of DBS, DBS-COOH, and DBS-CONHNH2 as Hydrogelators." Journal of Physical Chemistry A 121, no. 5 (February 2017): 1113–20. http://dx.doi.org/10.1021/acs.jpca.6b11130.

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Serdans, Beka. "DBS." Journal of Neuroscience Nursing 41, no. 1 (February 2009): 53–56. http://dx.doi.org/10.1097/jnn.0b013e318193457c.

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Newsom, Marilyn. "DBS Risks." Neurology Now 13, no. 4 (2017): 7. http://dx.doi.org/10.1097/01.nnn.0000522191.89343.48.

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Galkin, R. "DBS Programming." IEEE Journal on Selected Areas in Communications 3, no. 1 (1985): 215–18. http://dx.doi.org/10.1109/jsac.1985.1146173.

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Wood, David. "DBS standards." Journal of the Institution of Electronic and Radio Engineers 55, no. 11-12 (1985): 375. http://dx.doi.org/10.1049/jiere.1985.0121.

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Martin, Ernesto R. "DBS systems." Telecommunications Policy 9, no. 4 (December 1985): 291–300. http://dx.doi.org/10.1016/0308-5961(85)90022-9.

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Whitehead, Ian P., Que T. Lambert, Judith A. Glaven, Karon Abe, Kent L. Rossman, Gwendolyn M. Mahon, James M. Trzaskos, Robert Kay, Sharon L. Campbell, and Channing J. Der. "Dependence of Dbl and Dbs Transformation on MEK and NF-κB Activation." Molecular and Cellular Biology 19, no. 11 (November 1, 1999): 7759–70. http://dx.doi.org/10.1128/mcb.19.11.7759.

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ABSTRACT Dbs was identified initially as a transforming protein and is a member of the Dbl family of proteins (>20 mammalian members). Here we show that Dbs, like its rat homolog Ost and the closely related Dbl, exhibited guanine nucleotide exchange activity for the Rho family members RhoA and Cdc42, but not Rac1, in vitro. Dbs transforming activity was blocked by specific inhibitors of RhoA and Cdc42 function, demonstrating the importance of these small GTPases in Dbs-mediated growth deregulation. Although Dbs transformation was dependent upon the structural integrity of its pleckstrin homology (PH) domain, replacement of the PH domain with a membrane localization signal restored transforming activity. Thus, the PH domain of Dbs (but not Dbl) may be important in modulating association with the plasma membrane, where its GTPase substrates reside. Both Dbs and Dbl activate multiple signaling pathways that include activation of the Elk-1, Jun, and NF-κB transcription factors and stimulation of transcription from the cyclin D1 promoter. We found that Elk-1 and NF-κB, but not Jun, activation was necessary for Dbl and Dbs transformation. Finally, we have observed that Dbl and Dbs regulated transcription from the cyclin D1 promoter in a NF-κB-dependent manner. Previous studies have dissociated actin cytoskeletal activity from the transforming potential of RhoA and Cdc42. These observations, when taken together with those of the present study, suggest that altered gene expression, and not actin reorganization, is the critical mediator of Dbl and Rho family protein transformation.
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Kirkegaard-Nielsen, H., and O. May. "Der Einfluß des Double-Burst-Stimulierungsmusters (DBS) auf das Verhältnis zwischen DBS und Train-of-Four." AINS - Anästhesiologie · Intensivmedizin · Notfallmedizin · Schmerztherapie 30, no. 03 (May 1995): 163–66. http://dx.doi.org/10.1055/s-2007-996466.

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Franco, Ruth, Erich Fonoff, Pedro Alvarenga, Antonio Lopes, Euripides Miguel, Manoel Teixeira, Durval Damiani, and Clement Hamani. "DBS for Obesity." Brain Sciences 6, no. 3 (July 18, 2016): 21. http://dx.doi.org/10.3390/brainsci6030021.

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Dissertations / Theses on the topic "DBS"

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Rahm, Erhard. "Mehrrechner-Datenbanksysteme: Verteilte und Parallele DBS." Universität Leipzig, 2002. https://ul.qucosa.de/id/qucosa%3A32201.

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Behandelt werden - Anforderungen an Mehrrechner-DBS - Klassifikation - Verteilte und Parallele DBS - Katalogverwaltung, Namensverwaltung, Schemaarchitektur - Datenallokation in VDBS und PDBS - Verteilte und parallele Anfrageverarbeitung - Transaktionsverwaltung: Deadlock-Behandlung, Commit-Protokolle - Replizierte Datenbanken - Shared-Disk-DBS
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Monier, Pierre. "DBS multi-variables pour des problèmes de coordination multi-agents." Phd thesis, Université de Valenciennes et du Hainaut-Cambresis, 2012. http://tel.archives-ouvertes.fr/tel-00716275.

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Le formalisme CSP (Problème de Satisfaction de Contraintes) permet de représenter de nombreux problèmes de manière simple et efficace. Cependant, une partie de ces problèmes ne peut être résolue de manière classique et centralisée. Les causes peuvent être diverses : temps de rapatriement des données prohibitif, sécurité des données non garantie, etc. Les CSP Distribués(DisCSP), domaine intersectant celui des SMA et des CSP, permettent de modéliser et de résoudre ces problèmes naturellement distribués. Les raisonnements intra-agent et inter-agents sont alors basés sur un ensemble de relations entre différentes variables. Les agents interagissent afin de construire une solution globale à partir des solutions locales. Nous proposons, dans ce travail, un algorithme de résolution de DisCSP nommé Distributed Backtracking with Sessions (DBS) permettant de résoudre des DisCSP où chaque agent dispose d'un problème local complexe. DBS a la particularité de ne pas utiliser de nogoods comme la majorité des algorithmes de résolution de DisCSP mais d'utiliser à la place des sessions. Ces sessions sont des nombres permettant d'attribuer un contexte à chaque agent ainsi qu'à chaque message échangé durant la résolution du problème. Il s'agit d'un algorithme complet permettant l'utilisation de filtres sur les messages échangés sans remettre en cause la preuvede complétude. Notre proposition est évaluée, dans les cas mono-variable et multi-variables par agents, sur différents benchmarks classiques (les problèmes de coloration de graphes distribués et les DisCSP aléatoires) ainsi que sur un problème d'exploration en environnement inconnu.
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Braun, Maria. "Einfluss der intraoperativen Sedierung auf den klinischen Effekt der tiefen Hirnstimulation des Nucleus subthalamicus bei Patienten mit idiopatischem Parkinson-Syndrom." Doctoral thesis, Universitätsbibliothek Leipzig, 2011. http://nbn-resolving.de/urn:nbn:de:bsz:15-qucosa-74125.

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Ziel: Diese retrospektive Analyse sollte die Besserung nach tiefer Hirnstimulation in Abhängigkeit der verwendeten Medikamente zur Sedierung während der Elektrodenplatzierung vergleichen. Einführung: Deep brain stimulation (DBS) stellt eine effektive Therapieoption für Patienten mit fortgeschrittenem Morbus Parkinson dar. Sowohl die intraoperative Aktivität der subcortikalen Neurone als auch die intraoperative klinische Testung ist wichtig, um die exakte Elektrodenplatzierung zu kontrollieren. Beides könnte durch die Gabe von Sedativa, die intraoperativ zur Gewährleistung des Patientenkomforts und zur Optimierung der Operationsbedingungen verabreicht werden, beeinflußt werden. Material und Methoden: Wir analysierten retrospektiv die Daten von 47 Patienten, die Elektroden zur DBS implantiert bekamen. 7 Patienten erhielten während des Eingriffes keinerlei sedierende Medikation, 40 Patienten wurden Sedativa und/oder Analgetika verabreicht.( Propofol allein: n=13, Propofol und Remifentanyl: n=9, Propofol und Alfentanil: n=1, Remifentanil allein: n=13, Alfentanil und Midazolam: n=4) Ergebnisse: Es ergaben sich keine signifikanten Unterschiede zwischen den 5 Patientengruppen bezüglich der Besserung der Parkinson Symptome, gemessen an Hand der Unified Parkinson`s Disease Rating Scale Part III (UPDRS III) oder der Reduktion der Parkinson Medikamentendosis, analysiert als Levodopa Äquivalent Units (LEU). Untersuchten wir die Daten der Patienten, die Propofol während der Platzierung erhielten, zeigte sich ein signifikant schlechteres Ergebnis sowohl determiniert in der UPDRS III als auch in der LEU, verglichen mit den Patienten, die kein Propofol erhielten. Bei Einteilung der Patienten in Gruppen, die ein Opioid während der Platzierung erhielten, und Patienten die kein Opioid erhielten fielen keine signifikanten Unterschiede auf. Ergebnisse: Diese Daten könnten ein erster Hinweis sein, Propofol vorsichtig bei der Platzierung der Elektroden zur tiefen Hirnstimulation einzusetzen. Ein möglicher negativer Effekt des Propofols auf den klinischen Effekt der tiefen Hirnstimulation des Nucleus subthalamicus sollte aber in prospektiven Studien analysiert werden.
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West, Bryan Jason. "Chronoamperometric study of conformational relaxation in PPy(DBS)." College Park, Md. : University of Maryland, 2008. http://hdl.handle.net/1903/8333.

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Thesis (M.S.) -- University of Maryland, College Park, 2008.
Thesis research directed by: Dept. of Mechanical Engineering & Dept. of Aerospace Engineering. Title from t.p. of PDF. Includes bibliographical references. Published by UMI Dissertation Services, Ann Arbor, Mich. Also available in paper.
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Frässdorf, Wenke. "Rheologische und morphologische Charakterisierung von DBS-Netzwerkstrukturen in unterschiedlichen Polymermatrizes." [S.l. : s.n.], 2003. http://www.freidok.uni-freiburg.de/volltexte/822.

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Laird, Daniel T. "ADAPTIVE SIGNAL DEGRADATION INDICATION (SDI) FOR DIVERSITY BRANCH SELECTION (DBS)." International Foundation for Telemetering, 2003. http://hdl.handle.net/10150/605568.

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International Telemetering Conference Proceedings / October 20-23, 2003 / Riviera Hotel and Convention Center, Las Vegas, Nevada
One of several methods currently under investigation to increase telemetry efficiency is channel diversity selection. A spatial technique we are exploring exploits a signal quality indicator of phase demodulation to select ‘competing’ telemetry channels sourced by antenna separated by fractional wavelengths. The Advanced Range Telemetry (ARTM) program, a Centralized Test and Evaluation Improvement Program (CTEIP) research project funded by the Office of the Secretary of Defense (OSD), recently investigated three switching criteria for a multiple antenna system. This paper will discuss an algorithm that controls channel selection, or diversity branch selection (DBS), using a combination of the techniques investigated.
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Svensson, Malin, and Pauline Jolly. "Självskattad funktion av röst och tal hos patienter med essentiell tremor efter behandling med Deep Brain Stimulation : En jämförelse mellan patienter stimulerade i caudala zona incerta och en frisk kontrollgrupp." Thesis, Umeå universitet, Logopedi, 2014. http://urn.kb.se/resolve?urn=urn:nbn:se:umu:diva-98035.

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Sammanfattning Bakgrund: Deep brain stimulation (DBS) i nucleus ventralis intermedius i thalamus (VIM) eller caudala zona incerta (cZi) ger goda effekter på tremorsymptomen för patienter med essentiell tremor. Patienterna som behandlats med DBS kan få bieffekter som i vissa fall leder till talpåverkan, så kallad stimuleringsinducerad dysartri. Huruvida det finns risk för bieffekter som drabbar röstens funktion hos patienter med essentiell tremor saknas studier kring men man vet att grundsjukdomen kan påverka rösten akustiskt samt att vissa patienter utvecklar rösttremor. Att drabbas av en bieffekt efter DBS kan ha en inverkan på hur patienten subjektivt upplever resultatet av behandlingen.     Mål: Att undersöka om patienter med essentiell tremor som genomgått DBS subjektivt upplever någon form av röst- eller talbesvär jämfört med en frisk, ålders- och könsmatchad kontrollgrupp.   Metod: I studien deltog sammanlagt 42 deltagare varav 21 tillhörde en patientgrupp med essentiell tremor som genomgått DBS i cZi och de övriga 21 tillhörde en frisk, ålders- och könsmatchad kontrollgrupp. Deltagarna i de båda grupperna fick fylla i två formulär, RHI som berör röstens funktion och SOFT som berör talets funktion. Deltagarna som tillhörde patientgruppen fick också svara på fem fördjupande frågor om deras subjektiva upplevelse. Den statistiska signifikanstestningen genomfördes med avseende på om det fanns en skillnad i självskattningen mellan de båda grupperna.   Resultat: Resultaten i denna studie visade att patienterna med essentiell tremor s0m är behandlade med DBS skattar en signifikant större del subjektiva svårigheter av sin egen röst- och talfunktion jämfört med den friska kontrollgruppen.   Slutsats: Resultaten visade att det på gruppnivå finns signifikant större andel upplevda svårigheter relaterade till tal- och röstfunktionen hos patienter med essentiell tremor behandlade med DBS jämfört med en frisk kontrollgrupp. Resultaten visar även en stor individuell variation av den subjektiva upplevelsen av tal och röstpåverkan vilket är viktig information att delge patienter som ska genomgå DBS. Ett preoperativt samtal med logoped för information om möjliga bieffekter vid DBS och hur detta kan påverka patienten subjektivt är nödvändigt. De patienter som subjektivt upplever besvär med talet eller rösten bör erbjudas kontakt med logoped.
Abstract Background: Deep brain stimulation (DBS) of ventralis intermedius nucleus of thalamus (VIM) or caudala zona incerta (cZi) have been shown to be efficient in supressing tremor symptoms in patients with essential tremor. Patients who has been treated with DBS may acquire certain side effects of which in some cases results in an impact on the patients speech, known as stimulation- induced dysarthria. There is a lack of studies that investigate if there is a risk of side effects that is affecting voice functioning in patients with essential tremor. Previous studies have claimed that the disease itself may have an effect on the voice acoustics and that some patients develop voice tremor. The occurrence of a side effect caused by DBS may have an impact on the patients subjective experience of the treatment result.   Aim: To investigate whether patients with essential tremor treated with DBS are subjectively experiencing any form of voice or speech disability compared to a healthy, age and sex matched control group.   Method: The study included 42 participants all together whereof 21 was part of a patient group with essential tremor treated with DBS in cZi and the other 21 participants was part of a healthy, age and sex matched control group. The participants of both groups filled out two different forms, VHI (RHI) which affects voice function and SOFT which affects speech function. The participants in the patient group also answered five profound questions about their subjective experience. The test of statistical significance was performed with regard of if a difference was to be found in the self-ratings between the two groups.   Results: The results of the study show that patients with essential tremor whom have been treated with DBS rates a significantly greater amount of subjective difficulties related to the voice and speech functioning compared to the healthy control group.   Conclusion: The results show that the DBS-treated patients with essential tremor experience a significantly greater amount of subjective difficulties related to voice and speech functioning compared to a healthy control group. The results also show a great individual variety in the subjective experience of speech and voice function which is important information to notify patients who are due to undergo DBS-treatment. A preoperative meeting with a speech and language pathologist to be informed of possible side effects caused by the DBS and in what ways this can effect the patient subjectively is required. Patients who postoperatively experience a negative effect on speech or voice functioning should be offered contact with a speech and language pathologist.
Tal- och rösteffekter av djup hjärnstimulering hos patienter med ärftlig tremor
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Aslam, Adam Joshua. "EEG Characterization During Motor Tasks That Are Difficult for Movement Disorder Patients." DigitalCommons@CalPoly, 2017. https://digitalcommons.calpoly.edu/theses/1822.

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Movement disorders are a group of syndromes that often arise due to neurological abnormalities. Approximately 40 million Americans are affected by some form of movement disorder, significantly impacting patients’ quality of life and their ability to live independently. Deep brain stimulation (DBS) is one treatment that has shown promising results in the past couple decades, however, the currently used open-loop system has several drawbacks. By implementing a closed-loop or adaptive DBS (aDBS) system, the need for expensive parameter reprogramming sessions would be reduced, side-effects may be relieved, and habituation could be avoided. Several biomarkers, for example signals or activity derived from electroencephalogram (EEG), could potentially be used as a feedback source for aDBS. Here, we attempted to characterize cortical EEG potentials in healthy subjects performing six tasks that are difficult for those with movement disorders. Using a 32-channel EEG cap with an amplifier sampling at 500 Hz, we performed our protocol on 11 college-aged volunteers lacking any known movement disorder. For each task, we analyzed task-related power (TRP) changes, spectrograms, and topographical maps. In a finger movement exercise, we found task-related depression (TRD) in the delta band at the F4 electrode, as well as TRD at the C3 electrode in the alpha band during a pencil-pickup task, and TRD at the F3 electrode in the beta band during voluntary swallowing. While delta-ERD in the finger movement exercise was likely due to ocular artifact, the other significant results were in line with what relevant literature would predict. The findings from the work, in conjunction with a future study involving movement disorder patients, can provide insight into the use of EEG as a feedback source for aDBS. Keywords: EEG, electroencephalography, neurostimulation, deep brain stimulation, movement disorders, closed-loop DBS, adaptive DBS, aDBS
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Kania, Dramane. "Développement d’outils et de stratégies pour le diagnostic et le suivi biologique des infections VIH, VHB et VHC dans les pays à ressources limitées." Thesis, Montpellier 1, 2014. http://www.theses.fr/2014MON1T017/document.

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Le diagnostic et le suivi des infections par le VIH, VHB et VHC restent un défi dans les pays à faibles ressources qui sont par ailleurs les plus touchés. Il est urgent de pouvoir disposer d'outils de biologie simples, fiables et peu chers pour le contrôle de ces infections virales. Le défi est immense d'un point de vue clinique et politique de santé. L'objectif de ce travail de recherche effectué dans le cadre de la présente thèse est de développer et valider des stratégies et de nouveaux outils de biologie adaptés au diagnostic et au suivi des hépatites virales et de l'infection VIH dans les pays à ressources limitées. Dans un premier temps, nous avons investigué sur les résultats de sérologie VIH discordants, car en biologie et en pratique clinique, il est important d'établir le statut sérologique réel des personnes dépistées avec des résultats clairs pour une prise de décision adéquate à l'échelle individuelle. Dans ce travail, nous avons trouvé que les résultats discordants par l'algorithme de dépistage des femmes enceintes au Burkina Faso, étaient dans 94% des cas de faux positifs dus au test Determine™ HIV-1/2 et 4% de faux négatifs liés au test Genie II™ HIV-1/HIV-2. En matière de santé publique, les femmes présentant ce type de résultat peuvent être considérées comme séronégatives dans les centres où des investigations supplémentaires ne sont pas possibles, surtout dans les pays comme le Burkina Faso où la prévalence de l'infection est basse avec une faible diversité génétique. Dans un second temps, nous avons focalisé nos travaux sur la faisabilité d'une stratégie de dépistage qui combine la détection des trois infections (VIH, VHB et VHC) sur une seule carte DBS. Dans cette étude pilote, nous avons démontré que le DBS collecté en parallèle au test rapide VIH dans un centre de dépistage volontaire permet d'une part de faire la confirmation du VIH par immunoblot, et d'autre part de compléter par le diagnostic des hépatites B et C par ELISA suivi de western blot et PCR pour la confirmation pour le VHC. Cette stratégie peut servir de modèle pour promouvoir et vulgariser le dépistage des hépatites virales B et C dans les pays à ressources limitées. Le DBS peut servir de contrôle et de confirmation du diagnostic du VIH, VHB et VHC. Par la suite, nous avons évalué la performance de deux tests de 4ème génération immunoluminométriques (Elecsys® HIV Combi PT assay, Roche Diagnostics et Liaison® XL Murex HIV Ab/Ag test, DiaSorin) sur des échantillons séchés sur papier filtre en comparaison au test de diagnostic rapide et aux échantillons de sérum frais prélevés chez les patients en primo-infection VIH. Ces travaux ont clairement montré que les deux tests de 4ème génération réalisés sur papier filtre offrent de bonnes performances dans le diagnostic de la primo-infection par rapport aux tests de diagnostic rapide sur sérum frais. Cette méthode peut être utilisée pour détecter précocement le VIH chez les personnes difficiles à atteindre et les populations vivant dans des zones périphériques des pays à ressources limitées. Enfin, nous avons mis au point une technique de PCR en temps réel de détection et de quantification de l'ADN du VHB. A cet effet, nous sommes partis de deux PCR « maison » ciblant deux régions génomiques différentes (gène X pour la qPCR 1 et gène S pour la qPCR 2) en comparaison à un test commercial de charge virale (Cobas AmpliPrep/Cobas TaqMan HBV Test, version 2.0, Roche Diagnostics). La qPCR 2 avec un seuil de détection à 91 UI/ml (vs 104 UI/ml pour la qPCR 1) a montré une meilleure performance dans la quantification de l'ADN du VHB. Cette qPCR 2 peu chère est aujourd'hui produite sous forme de kit par une start-up appelée OMUNIS. Ce kit en développement fera l'objet d'une évaluation multicentrique en France, en Afrique et en Asie du Sud-Est à travers un réseau de laboratoires sous la promotion de l'ANRS
Diagnosis and management of hepatitis B, hepatitis C and HIV infections are a real challenge in middle and low-income countries. There is an urgent need for simple, reliable and inexpensive tools to control these infections in high prevalence sittings like Africa and Asia. The challenge is immense in clinical and public health policy hands. The main goal of this research work performed for our PhD is the development and validation of strategies and tools to diagnose and monitor HIV, HBV and HCV infections in resource-constrained countries. At a first step, we investigated the results of HIV discordant results, since it is important to establish the real HIV status of people tested with clear results for appropriate decision-making in biological and clinical practice. This work show that discordant results obtained in the algorithm of HIV screening among pregnant women in Burkina Faso, are false positive results in 94% of cases due to the Determine™ HIV-1/2 immunochromatographic test and false negative results in 4% of cases due to the Genie II ™ HIV-1 / HIV-2 test. In public health practice, women with this type of result can be considered as negative for HIV testing in centers where additional investigations are not possible, especially in countries like Burkina Faso with a low incidence and a low genetic diversity of HIV.In a second step, we focused our work on the feasibility of a screening strategy that detects HIV, HBV and HCV infections into a single card of DBS. In this pilot study, we demonstrated that DBS collected in parallel to HIV rapid testing in a voluntary counseling and testing center allows HIV confirmation using immunoblotting, and an additional testing by diagnosing HBV and HCV using ELISA followed by immunoblotting and PCR for HCV confirmation. This strategy can serve as a model to promote and scale-up the screening of HBV and HCV in resource-limited countries. DBS can be served as control and confirmation of HIV, HBV and HCV diagnosis. Furthermore, we evaluated the performance of two 4th generation chemiluminescent immunoassays (Elecsys HIV Combi PT assay, Roche Diagnostics and Liaison XL Murex HIV Ab/Ag test, DiaSorin) tested on filter paper samples in comparison to rapid diagnostic test and fresh serum samples from patients with acute HIV infection. These studies have clearly shown that the two 4th generation tests performed on filter paper offer good performance in terms of sensitivity for the diagnosis of HIV infection in its early phases compared with rapid diagnostic tests. This approach may be used in combination with HIV rapid tests in hard-to-reach individuals and populations living in remote areas of when an early HIV infection is suspected since rapid tests do not offer appropriate performance in this case.Finally, we developed a real-time PCR for HBV DNA detection and quantification. In this study, we evaluated two in-house PCR targeting two different regions of HBV genome (X gene for qPCR 1 and S gene for qPCR 2) in comparison with a commercial Roche HBV DNA test (Cobas AmpliPrep / Cobas TaqMan HBV Test, version 2.0, Roche Diagnostics) as a gold standard. The qPCR 2 with a low detection limit of 91 IU/ml (vs 104 IU/ml for 1 qPCR) showed a better performance in HBV DNA quantification. This inexpensive qPCR with best performance characteristics is producing by a start-up called OMUNIS. This kit will be evaluated in France, in Africa and in South and East Asia in a research study funded by ANRS (France REcherche Nord & sud Sida-hiv Hépatites)
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Keita, Abdelaye. "Prise en charge de l’infection par HIV-1 dans les pays en développement : aspects diagnostiques et évaluation immuno-virologique de l’efficacité thérapeutique dans le sang et les compartiments muqueux." Thesis, Lyon, 2018. http://www.theses.fr/2018LYSES061/document.

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A l’ère de l’objectif cible « 90-90-90 » de l’ONUSIDA de réduction de la pandémie liée à HIV, il est important d’évaluer régulièrement la cascade de prise en charge des personnes vivant avec le virus HIV afin d’en vérifier l’avancement et d’identifier d’éventuels obstacles à sa réalisation. Pour cela nous avons étudié tout d’abord efficacité du traitement antirétroviral (TAR) dans le sang de personnes nouvellement dépistées séropositives à Bamako (Mali). Dans un deuxième travail nous avons évalué la faisabilité des tests de charge virale et de résistance génotypique aux antirétroviraux à partir de sang total séché sur un support de type buvard (DBS). La troisième partie de nos travaux était consacrée à des aspects plus physiopathologiques avec l’évaluation du traitement sur les réservoirs salivaires et génitaux (patients de Bamako) et sur le microbiote vaginal, ainsi que l’étude du profil de résistance des souches archivées dans l’ADN cellulaire de biopsies rectales. Nous avons tout d’abord observé un taux important de perdus de vue à un an dans la cohorte de Bamako (environ 45%). Nous avons également constaté un taux élevé de résistance primaire aux ARV à Bamako et au Tchad (>15%). De manière rassurante, le succès virologique au bout de 1 an chez les personnes traitées était d’environ 90% ce qui correspond à l’objectif de l’ONUSIDA (3ème 90) et un faible niveau de mutations acquises a été observé chez ces personnes adhérentes au traitement. Nous avons démontré l’efficacité du TAR sur le compartiment salivaire et constaté une compartimentation du virus au niveau cervico-vaginal chez certaines femmes traitées (27%) présentant une excrétion virale au niveau vaginal avec une charge virale plasmatique indétectable et/ou des séquences génétiques différentes sur le gène pol entre le virus isolé dans la muqueuse et celui provenant du sang. De plus, une dysbiose était observée avant la mise sous traitement, avec normalisation de la flore sous TAR efficace. En ce qui concerne le travail sur les biopsies rectales, des profils similaires ont été observés entre la souche plasmatique majoritaire au moment de la mise sous TAR et celle archivée dans le rectum 1 à 5 ans après traitement. En conclusion, nos travaux apportent des informations nouvelles sur le déroulement des différentes étapes de la prise en charge de l’infection par HIV dans les pays en développement : tout d’abord une faible adhésion au traitement ce qui peut constituer un obstacle majeur à la réalisation du plan 90/90/90 ; une forte prévalence de la résistance primaire qui plaident en faveur de l’accessibilité aux différentes classes d’antirétroviraux et de leur utilisation rationnelle, de l’utilisation généralisée en routine des tests de charge virale et du développement d’un réseau de surveillance de la résistance aux ARV dans les pays à ressources limitées ; des données d’efficacité de traitement sur les réservoirs muqueux mettant en évidence l’existence d’une dysbiose et d’une compartimentation du virus au niveau génital ce qui pose le problème du risque résiduel de transmission chez certaines personnes, même sous ARV
Regularly assess to UNAIDS cascade 90-90-90 is important to check the progress and identify any obstacles to its implementation. For this we first studied efficacy of antiretroviral treatment (ART) in the blood of newly diagnosed HIV-positive in Bamako (Mali).In a second work we evaluated the feasibility of viral load and genotypic resistance tests from dried blood spot (DBS). The third part of our work is dedicated to pathophysiological aspects with evaluation of treatment on salivary and genital reservoirs (Bamako patients) and on the vaginal microbiota, as well as the study of the resistance profile of the strains archived in cellular DNA of rectal biopsies. We observed a high rate of lost to follow-up at one year in the Bamako cohort (45%). We also found a high rate of ART primary resistance in Bamako and Chad (> 15%). Reassuringly, the virological success after 1 year of treated follow was about 90% in these adherents. We also demonstrated the efficacy of ART in the salivary compartment and found a compartmentalization of the virus at the cervico-vaginal level in some women under ART. In addition, a dysbiosis was observed before ART, and a normal flora under effective ART. Similar profiles were observed on the main strain isolated in blood at the time of diagnosis and on the archived strain in the rectum after 1 to 5 years of ART.In conclusion, our work provides new information on the progress of the treatment stages of HIV infection in developing countries: low adherence to treatment which can constitute a major obstacle to achieve the plan 90/90/90; a high prevalence of primary resistance advocating accessibility and rational use of different classes of antiretrovirals drugs, widespread routine use of viral load tests and the development of ARVs resistance surveillance network in resource-limited countries; treatment efficacy data on mucosal reservoirs revealing the existence of genital dysbiosis and viral compartmentalization, which raises the problem of the residual risk of transmission in some people, even under ARVs
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Books on the topic "DBS"

1

Wall, G. The DBS report. Ottawa, Ont: Canadian Cable Television Association, 1992.

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Bower, Linda Lee. The global DBS market. Dallas, TX: MegaTech Resources, 1998.

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Bower, Linda Lee. DBS lights up the sky! Dallas, TX (2817 Andrea Lane, Dallas 75228): MegaTech Resources, 1996.

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James, Wood. Satellite communications and DBS systems. Oxford [England]: Focal Press, 1992.

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Knee, M. J. DBS pay television: Picture signal scrambling. London: British Broadcasting Corporation, 1985.

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Maddocks, M. C. D. A flat-plate antenna for DBS reception. London: BBC, 1988.

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Publications, Key Note, ed. Cable TV/DBS: An industry sector overview. 2nd ed. London: Key Note Publications, 1987.

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author, Giroux Monique L., ed. DBS: A patient guide to deep brain stimutlation. Englewood, Colorado: Movement & Neuroperformance Center Colorado, P.C., 2013.

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Maddocks, M. C. D. Array elements for a DBS flat-plate antenna. London: BBC, 1988.

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Maddocks, M. C. D. Polarisation converters for a DBS flat-plate antenna. London: BBC, 1988.

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Book chapters on the topic "DBS"

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Simola, Nicola, Micaela Morelli, Tooru Mizuno, Suzanne H. Mitchell, Harriet de Wit, H. Valerie Curran, Celia J. A. Morgan, et al. "DBS." In Encyclopedia of Psychopharmacology, 365. Berlin, Heidelberg: Springer Berlin Heidelberg, 2010. http://dx.doi.org/10.1007/978-3-540-68706-1_4177.

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Gooch, Jan W. "DBS." In Encyclopedic Dictionary of Polymers, 194. New York, NY: Springer New York, 2011. http://dx.doi.org/10.1007/978-1-4419-6247-8_3300.

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van Cann, Roderick, Slinger Jansen, and Sjaak Brinkkemper. "DBS." In Software Business Start-up Memories, 51–56. London: Palgrave Macmillan UK, 2013. http://dx.doi.org/10.1057/9781137280473_5.

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Thrun, Michael Christoph. "Databionic Swarm (DBS)." In Projection-Based Clustering through Self-Organization and Swarm Intelligence, 91–106. Wiesbaden: Springer Fachmedien Wiesbaden, 2018. http://dx.doi.org/10.1007/978-3-658-20540-9_8.

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Gabriëls, L., P. Cosyns, K. van Kuyck, and B. Nuttin. "DBS for OCD." In Textbook of Stereotactic and Functional Neurosurgery, 2897–924. Berlin, Heidelberg: Springer Berlin Heidelberg, 2009. http://dx.doi.org/10.1007/978-3-540-69960-6_173.

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Stecher, Benjamin, and Alfonso Fasano. "DBS in Crisis." In Reprogramming the Brain, 141–44. Cham: Springer Nature Switzerland, 2024. http://dx.doi.org/10.1007/978-3-031-50399-3_22.

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Hausser, Roland. "Outline of DBS." In Ontology of Communication, 21–33. Cham: Springer Nature Switzerland, 2023. http://dx.doi.org/10.1007/978-3-031-22739-4_3.

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Stecher, Benjamin, and Alfonso Fasano. "To DBS or not to DBS…That Is the Question." In Reprogramming the Brain, 11–19. Cham: Springer Nature Switzerland, 2024. http://dx.doi.org/10.1007/978-3-031-50399-3_3.

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Rahm, Erhard. "Synchronisationstechniken für zentralisierte DBS." In Synchronisation in Mehrrechner-Datenbanksystemen, 27–45. Berlin, Heidelberg: Springer Berlin Heidelberg, 1988. http://dx.doi.org/10.1007/978-3-642-74123-4_4.

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Rahm, Erhard, Gunter Saake, and Kai-Uwe Sattler. "Datenverteilung in Parallelen DBS." In Verteiltes und Paralleles Datenmanagement, 107–35. Berlin, Heidelberg: Springer Berlin Heidelberg, 2015. http://dx.doi.org/10.1007/978-3-642-45242-0_6.

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Conference papers on the topic "DBS"

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Chen, C. H., N. Li, and W. Wu. "Microstrip DBR diplexer with DBS." In 2012 4th International High Speed Intelligent Communication Forum (HSIC). IEEE, 2012. http://dx.doi.org/10.1109/hsic.2012.6212953.

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Bartolini, Andrea, Martino Ruggiero, and Luca Benini. "HVS-DBS." In the seventh ACM international conference. New York, New York, USA: ACM Press, 2009. http://dx.doi.org/10.1145/1629335.1629339.

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SALKELD, BRIAN. "Engineering for UK DBS." In 12th International Communication Satellite Systems Conference. Reston, Virigina: American Institute of Aeronautics and Astronautics, 1988. http://dx.doi.org/10.2514/6.1988-803.

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Ando, Mak. "New DBS receiver antennas." In 23rd European Microwave Conference, 1993. IEEE, 1993. http://dx.doi.org/10.1109/euma.1993.336796.

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Hollister, Brad E., Gordon Duffley, Chris Butson, Chris Johnson, and Paul Rosen. "Visual Inspection of DBS Efficacy." In 2019 IEEE Visualization Conference (VIS). IEEE, 2019. http://dx.doi.org/10.1109/visual.2019.8933720.

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Jing, Changyong, and Shaohua Ling. "Electrochemical DBS Wastewater Treatment Research." In 5th International Conference on Advanced Design and Manufacturing Engineering. Paris, France: Atlantis Press, 2015. http://dx.doi.org/10.2991/icadme-15.2015.129.

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Larson, L. "DBS, VSAT, and the future." In Short Course High Frequency Design for Communications. IEEE, 1996. http://dx.doi.org/10.1109/hfdc.1996.864094.

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Allebach, Jan P. "DBS: retrospective and future directions." In Photonics West 2001 - Electronic Imaging, edited by Reiner Eschbach and Gabriel G. Marcu. SPIE, 2000. http://dx.doi.org/10.1117/12.410810.

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Walters, David, Branimir Vojcic, Fatih Alagoz, Amina AlRustamani, and Raymond Pickholtz. "Managing congestion in DBS networks." In 18th International Communications Satellite Systems Conference and Exhibit. Reston, Virigina: American Institute of Aeronautics and Astronautics, 2000. http://dx.doi.org/10.2514/6.2000-1241.

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AUBOIN, J. "Second generation DBS satellite TWTs." In 14th International Communication Satellite Systems Conference and Exhibit. Reston, Virigina: American Institute of Aeronautics and Astronautics, 1992. http://dx.doi.org/10.2514/6.1992-1820.

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Reports on the topic "DBS"

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Scott, Ann, Joanna Duncan, David Tivey, and Wendy Babidge. Paediatric deep brain stimulation. The Sax Institute, October 2019. http://dx.doi.org/10.57022/iksx3206.

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This review aimed to assess the evidence around the use of deep brain stimulation (DBS) for paediatric patients with severe dystonia. It aimed to answer the following questions: 1) Is paediatric DBS safe, efficacious and cost effective when compared with best supportive care?, 2) Is DBS more safe or more effective for some types of paediatric dystonia than others? Are there agreed patient selection criteria?, 3) What models of care and service delivery or access and funding mechanisms are established to deliver paediatric DBS internationally?. The available evidence is limited but the growing body of level IV evidence generally supports use of DBS for improving motor function and disability. More data is needed that looks as other aspects of patient wellbeing.
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Tow Leong, Tiang, Mohd Saufi Ahmad, Ang Qian Yee, Syahrun Nizam Md Arshad@Hashim, Mohd Faizal Mohd Zahir, Mohd Azlizan Moh Adib, Nazril Husny, Tan Kheng Kwang, and Dahaman Ishak. HANDBOOK OF ELECTRICAL SYSTEM DESIGN FOR NON-DOMESTIC BUILDING. Penerbit Universiti Malaysia Perlis, 2023. http://dx.doi.org/10.58915/techrpt2023.001.

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This technical report presents the electrical system installation design for development of a factory with 1 storey and 2 storey of offices. Firstly, the general methodology of designing the electrical system are elaborated in this report. As overall, the methodologies in designing the components of the electrical system are explained and elaborated, which included: (a) load and maximum demand estimation; (b) miniature circuit breaker (MCB) selection; (c) moulded case circuit breaker (MCCB) selection; (d) air circuit breaker (ACB) selection, (e) residual current device (RCD) selection; (f) protection relay selection; (g) current transformer (CT) selection; (h) sizing selection for cable and live conductors; (i) capacitor bank selection for power factor correction (PFC); and (j) distribution transformer and its protection devices selection. Then, the electrical system of this project is computed and designed by using the methodologies aforementioned. Firstly, the electrical system of various distribution boards (DBs) with the protection/metering devices along with its phase and earthing cables for every final circuits are designed and installed in the factory. Next, the installation is proceeded with the electrical system of main switchboard (MSB) with the protection/metering devices along with its phase and earthing cables for every DBs. Also, the electrical system of PFC by using detuned capacitor bank with various protection/metering devices is designed and built in the plant. Apart from that, the factory is equipped with the electrical system of high tension (HT) room that included the distribution power transformer with the protection/metering devices along with its phase and earthing cables. Lastly, the methodologies and the computation design of the electrical system installation in the context of connected load, load currents, maximum demand, MCB, MCCB, ACB, RCD, protection relay, metering CTs, live cable, protection conductor/earth cable, detuned capacitor bank, and distribution transformer, are prepared according to several important standards, for instance, the MS IEC 60364, Electrical Installations for Buildings, Suruhanjaya Tenaga (ST) – Non-Domestic Electrical Installation Safety Code, Electricity Supply Application Handbook, Tenaga Nasional Berhad (TNB).
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Koessl, Gerald. Das System des gemeinnützigen Wohnbaus in Österreich. Liège: CIRIEC, 2022. http://dx.doi.org/10.25518/ciriec.wp202205.

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Der gemeinnützige Wohnbau spielt auf dem österreichischen Wohnungsmarkt eine bedeutende Rolle. Rund ein Viertel aller Haushalte lebt in Wohnungen, die entweder von einer gemeinnützigen Bauvereinigung (GBV) vermietet oder als Eigentumswohnung verwaltet werden. GBVs zeichnen sich durch ein besonderes Geschäftsmodell aus, das auf den Prinzipien der Kostendeckung und der revolvierenden Mittel beruht. Indem diese Prinzipien sowohl von der Logik des gewinnorientierten Wohnungsbaus als auch vom öffentlichen Wohnungsbau abweichen, nehmen GBVs eine besondere Rolle als Akteure des Dritten Sektors am österreichischen Wohnungsmarkt ein. In diesem Papier werden die wichtigsten Mechanismen und Grundsätze des gemeinnützigen Wohnbaus beschrieben, einschließlich der Art der Finanzierung, der Festlegung der Mieten, der in die Preiskalkulation einfließenden Komponenten und der Verwendung von revolvierenden Fonds zur Finanzierung des künftigen Baus von leistbaren Wohnungen. Außerdem werden die Auswirkungen des Geschäftsmodells der GBVs auf das Mietniveau erläutert und anhand einer kürzlich durchgeführten Studie die ökonomischen Auswirkungen aufgezeigt.
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Sheikh, Sonja, Iris Fischl, Vivien Lo, Thomas Stahlecker, Petra Wagner-Luptacik, and Simone Archut. Interimevaluierung von protec 2002+. Das Programm zur Förderung des Technologietransfer. KMU Forschung Austria, May 2006. http://dx.doi.org/10.22163/fteval.2006.170.

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Torres, Vidal, and Juan Sotomayor. Calibração das instabilidades e comportamento dos taludes da cava N4WS. ITV, 2020. http://dx.doi.org/10.29223/prod.tec.itv.mi.2020.42.torres.

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Bosshart, David, Karin Frick, Stephan Fetsch, and Holger Wildgrube. Das Ende des Konsums – Wenn Daten den Handel überflüssig machen. Gdi-verlag, Gottlieb Duttweiler Institute, 2019. http://dx.doi.org/10.59986/ctke6207.

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Bießlich, Susan, Sebastian von Engelhardt, Peter Kaufmann, Christiane Kerlen, Sonja Kind, Jakob Kofler, Anja Marcher, et al. Evaluation des nationalen Programms für Weltraum und Innovation. Iit – Institut für Innovation und Technik VDI/VDE-IT, March 2021. http://dx.doi.org/10.22163/fteval.2021.580.

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Mit dem Nationalen Programm für Weltraum und Innovation - Forschungs- und Entwicklungsvorhaben (NPWI) stärkt das deutsche Bundesministerium für Wirtschaft und Energie (BMWi) die Innovations- und Wettbewerbsfähigkeit des deutschen Raumfahrtinnovationsökosystems aus Forschung und Industrie. Orientierungsrahmen des NPWI ist die Raumfahrtstrategie der Bundesregierung „Für eine zukunftsfähige deutsche Raumfahrt“. Umgesetzt wird das Programm durch das DLR Raumfahrtmanagement (DLR-RFM). Für die hier vorliegende Evaluation des NPWI für 2011 bis 2018 beauftragte das BMWi das Institut für Innovation und Technik und seine Partner Kerlen Evaluation und KMU Forschung Austria. Analysiert und bewertet wurde, inwieweit das NPWI seine Ziele erreichte, welche Wirkungen es zeitigte und wie es wirtschaftlich umgesetzt wurde. Angesichts identifizierter Anpassungsbedarfe wurden Handlungsempfehlungen an das BMWi sowie das DLR-Raumfahrtmanagement gerichtet.
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Tangemann, Kirsten, and Siegfried Vössner. Das AplusB Programm 2002 – 2009: Ergebnisse aus der Analyse des Gründungsmonitorings. Quadris Consulting GmbH, September 2010. http://dx.doi.org/10.22163/fteval.2010.84.

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Machado Sánchez, Hugo, Eliane Gouveia de Morais Sanchez, and Hildenise Souza Santos. Qualidade de vida no trabalho dos docentes universitários das ciências exatas. Buenos Aires: siicsalud.com, June 2016. http://dx.doi.org/10.21840/siic/149035.

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Cordeiro, João Pedro. Os «quadros» como agentes estratégicos de desenvolvimento das organizações: contributos para uma análise das funções dos quadros superiores. DINÂMIA'CET-IUL, 2009. http://dx.doi.org/10.7749/dinamiacet-iul.wp.2009.84.

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